TreeWAS – Variant ID: rs74343026

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter XX External causes of morbidity and mortality	1.000	0.000
Chapter II Neoplasms	0.998	0.002
Chapter VI Diseases of the nervous system	0.998	0.002
Chapter XIV Diseases of the genitourinary system	0.996	0.004
Chapter XV Pregnancy, childbirth and the puerperium	0.993	0.007
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.993	0.007
Chapter X Diseases of the respiratory system	0.992	0.008
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.988	0.012
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.988	0.012
J20-J22 Other acute lower respiratory infections	0.987	0.013
C50-C50 Malignant neoplasm of breast	0.987	0.013
N17-N19 Renal failure	0.985	0.015
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.985	0.015
J22 Unspecified acute lower respiratory infection	0.980	0.020
C50 Malignant neoplasm of breast	0.979	0.021
W00-W19 Falls	0.977	0.023
G50-G59 Nerve, nerve root and plexus disorders	0.974	0.026
G40-G47 Episodic and paroxysmal disorders	0.973	0.027
G47 Sleep disorders	0.971	0.029
N60-N64 Disorders of breast	0.969	0.031
G47.3 Sleep apnoea	0.961	0.039
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.961	0.039
C34 Malignant neoplasm of bronchus and lung	0.959	0.041
G90-G99 Other disorders of the nervous system	0.959	0.041
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.954	0.046
D70-D77 Other diseases of blood and blood-forming organs	0.952	0.048
C50.9 Breast, unspecified	0.950	0.050
O60-O75 Complications of labour and delivery	0.949	0.051
O94-O99 Other obstetric conditions, not elsewhere classified	0.947	0.053
O72 Postpartum haemorrhage	0.946	0.054
C50.2 Upper-inner quadrant of breast	0.946	0.054
W19 Unspecified fall	0.943	0.057
N20-N23 Urolithiasis	0.941	0.059
O72.1 Other immediate postpartum haemorrhage	0.929	0.071
N00-N08 Glomerular diseases	0.927	0.073
N17 Acute renal failure	0.923	0.076
Chapter I Certain infectious and parasitic diseases	0.921	0.079
Y95 Nosocomial condition	0.921	0.079
C34.9 Bronchus or lung, unspecified	0.921	0.079
N60 Benign mammary dysplasia	0.920	0.080
J09-J18 Influenza and pneumonia	0.917	0.083
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.914	0.086
W19.9 Unspecified place	0.912	0.088
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.911	0.089
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.909	0.091
N18 Chronic renal failure	0.908	0.092
G58 Other mononeuropathies	0.902	0.098
D68 Other coagulation defects	0.899	0.101
N20 Calculus of kidney and ureter	0.898	0.102
Y51 Drugs primarily affecting the autonomic nervous system	0.896	0.104
J00-J06 Acute upper respiratory infections	0.895	0.105
O72.2 Delayed and secondary postpartum haemorrhage	0.892	0.108
D70 Agranulocytosis	0.891	0.109
A30-A49 Other bacterial diseases	0.887	0.113
C32 Malignant neoplasm of larynx	0.886	0.114
C83 Diffuse non-Hodgkin's lymphoma	0.882	0.118
N17.9 Acute renal failure, unspecified	0.881	0.119
G93 Other disorders of brain	0.876	0.124
W17 Other fall from one level to another	0.875	0.125
N10-N16 Renal tubulo-interstitial diseases	0.875	0.125
C34.3 Lower lobe, bronchus or lung	0.874	0.126
Y48 Anaesthetics and therapeutic gases	0.872	0.128
G57 Mononeuropathies of lower limb	0.870	0.130
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.863	0.137
C81 Hodgkin's disease	0.862	0.138
D75 Other diseases of blood and blood-forming organs	0.856	0.144
N18.2 Chronic kidney disease, stage 2	0.856	0.144
G00-G09 Inflammatory diseases of the central nervous system	0.855	0.145
N19 Unspecified renal failure	0.853	0.147
C51-C58 Malignant neoplasms of female genital organs	0.853	0.147
A41 Other septicaemia	0.852	0.148
D68.9 Coagulation defect, unspecified	0.852	0.148
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.850	0.150
D66 Hereditary factor VIII deficiency	0.848	0.152
J86 Pyothorax	0.847	0.153
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.846	0.154
C91 Lymphoid leukaemia	0.845	0.155
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.844	0.156
G58.9 Mononeuropathy, unspecified	0.841	0.159
G90 Disorders of autonomic nervous system	0.837	0.163
N20.2 Calculus of kidney with calculus of ureter	0.837	0.163
J13 Pneumonia due to Streptococcus pneumoniae	0.836	0.164
N63 Unspecified lump in breast	0.835	0.165
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.832	0.168
N61 Inflammatory disorders of breast	0.828	0.172
N60.1 Diffuse cystic mastopathy	0.824	0.176
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.821	0.179
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.821	0.179
G47.0 Disorders of initiating and maintaining sleep [insomnias]	0.819	0.181
V80-V89 Other land transport accidents	0.819	0.181
J17 Pneumonia in diseases classified elsewhere	0.816	0.184
N60.8 Other benign mammary dysplasias	0.816	0.184
G93.9 Disorder of brain, unspecified	0.814	0.186
O80-O84 Delivery	0.813	0.187
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.813	0.187
N13 Obstructive and reflux uropathy	0.812	0.188
C90 Multiple myeloma and malignant plasma cell neoplasms	0.811	0.189
Y43 Primarily systemic agents	0.810	0.190
J20 Acute bronchitis	0.809	0.190
G96 Other disorders of central nervous system	0.809	0.191
G57.6 Lesion of plantar nerve	0.805	0.195
J01 Acute sinusitis	0.800	0.200
W07 Fall involving chair	0.800	0.200
W13 Fall from, out of or through building or structure	0.798	0.202
Y44 Agents primarily affecting blood constituents	0.798	0.202
N21 Calculus of lower urinary tract	0.795	0.205
G95 Other diseases of spinal cord	0.795	0.205
C30 Malignant neoplasm of nasal cavity and middle ear	0.794	0.206
Q20-Q28 Congenital malformations of the circulatory system	0.794	0.206
W19.1 Residential institution	0.794	0.206
G93.3 Postviral fatigue syndrome	0.791	0.209
N62 Hypertrophy of breast	0.789	0.211
N20.1 Calculus of ureter	0.788	0.212
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.787	0.213
B50-B64 Protozoal diseases	0.787	0.213
A41.1 Septicaemia due to other specified staphylococcus	0.786	0.214
O73 Retained placenta and membranes, without haemorrhage	0.784	0.216
C32.0 Glottis	0.783	0.217
N18.5 Chronic kidney disease, stage 5	0.783	0.217
N60.9 Benign mammary dysplasia, unspecified	0.781	0.219
Q50-Q56 Congenital malformations of genital organs	0.779	0.221
Y00-Y09 Assault	0.778	0.222
G59 Mononeuropathy in diseases classified elsewhere	0.778	0.222
J03 Acute tonsillitis	0.777	0.223
Y52 Agents primarily affecting the cardiovascular system	0.777	0.223
D80-D89 Certain disorders involving the immune mechanism	0.777	0.223
C88 Malignant immunoproliferative diseases	0.776	0.224
J15 Bacterial pneumonia, not elsewhere classified	0.774	0.226
C92 Myeloid leukaemia	0.772	0.228
C49 Malignant neoplasm of other connective and soft tissue	0.771	0.229
J80-J84 Other respiratory diseases principally affecting the interstitium	0.770	0.230
C50.4 Upper-outer quadrant of breast	0.770	0.230
Y48.2 Other and unspecified general anaesthetics	0.770	0.230
D75.1 Secondary polycythaemia	0.769	0.231
J86.9 Pyothorax without fistula	0.766	0.234
N02 Recurrent and persistent haematuria	0.765	0.235
Y41 Other systemic anti-infectives and antiparasitics	0.765	0.235
N18.3 Chronic kidney disease, stage 3	0.764	0.236
C50.8 Overlapping lesion of breast	0.760	0.240
A41.9 Septicaemia, unspecified	0.760	0.240
W17.4 Street and highway	0.759	0.241
N03 Chronic nephritic syndrome	0.758	0.242
D69 Purpura and other haemorrhagic conditions	0.758	0.242
G54 Nerve root and plexus disorders	0.757	0.243
O72.0 Third-stage haemorrhage	0.756	0.244
C91.1 Chronic lymphocytic leukaemia	0.755	0.245
D68.8 Other specified coagulation defects	0.755	0.245
X60-X84 Intentional self-harm	0.754	0.246
V01-V09 Pedestrian injured in transport accident	0.753	0.247
G47.9 Sleep disorder, unspecified	0.753	0.247
O85-O92 Complications predominantly related to the puerperium	0.753	0.247
X58-X59 Accidental exposure to other and unspecified factors	0.753	0.247
W19.3 Sports and athletics area	0.753	0.247
O75 Other complications of labour and delivery, not elsewhere classified	0.748	0.252
G47.1 Disorders of excessive somnolence [hypersomnias]	0.748	0.252
G47.8 Other sleep disorders	0.748	0.252
O61 Failed induction of labour	0.748	0.252
J21 Acute bronchiolitis	0.746	0.254
A15-A19 Tuberculosis	0.746	0.254
C34.1 Upper lobe, bronchus or lung	0.746	0.254
Y47 Sedatives, hypnotics and antianxiety drugs	0.746	0.254
W10 Fall on and from stairs and steps	0.745	0.255
B20-B24 Human immunodeficiency virus [HIV] disease	0.745	0.255
W50-W64 Exposure to animate mechanical forces	0.745	0.255
C71 Malignant neoplasm of brain	0.744	0.256
N13.8 Other obstructive and reflux uropathy	0.744	0.256
N04 Nephrotic syndrome	0.743	0.257
C81.9 Hodgkin's disease, unspecified	0.742	0.257
J11 Influenza, virus not identified	0.739	0.261
Y46 Antiepileptics and anti-Parkinsonism drugs	0.735	0.264
G70-G73 Diseases of myoneural junction and muscle	0.735	0.265
G50 Disorders of trigeminal nerve	0.734	0.266
G47.4 Narcolepsy and cataplexy	0.734	0.266
G06 Intracranial and intraspinal abscess and granuloma	0.734	0.266
J01.9 Acute sinusitis, unspecified	0.733	0.267
A41.0 Septicaemia due to Staphylococcus aureus	0.732	0.268
C50.5 Lower-outer quadrant of breast	0.728	0.272
Y60-Y69 Misadventures to patients during surgical and medical care	0.728	0.272
W20-W49 Exposure to inanimate mechanical forces	0.728	0.272
G95.2 Cord compression, unspecified	0.728	0.272
N20.9 Urinary calculus, unspecified	0.727	0.273
J17.3 Pneumonia in parasitic diseases	0.726	0.274
G90.2 Horner's syndrome	0.725	0.275
N05 Unspecified nephritic syndrome	0.725	0.275
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.722	0.277
C83.0 Small cell (diffuse)	0.721	0.278
V40-V49 Car occupant injured in transport accident	0.721	0.279
W17.5 Trade and service area	0.720	0.279
B35-B49 Mycoses	0.720	0.280
W07.0 Home	0.720	0.280
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.718	0.282
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
Y35-Y36 Legal intervention and operations of war	0.717	0.283
Y10-Y34 Event of undetermined intent	0.717	0.283
X85-X99 Assault	0.717	0.283
X30-X39 Exposure to forces of nature	0.717	0.283
X10-X19 Contact with heat and hot substances	0.717	0.283
X00-X09 Exposure to smoke, fire and flames	0.717	0.283
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.717	0.283
W75-W84 Other accidental threats to breathing	0.717	0.283
W65-W74 Accidental drowning and submersion	0.717	0.283
V98-V99 Other and unspecified transport accidents	0.717	0.283
V95-V97 Air and space transport accidents	0.717	0.283
V90-V94 Water transport accidents	0.717	0.283
V70-V79 Bus occupant injured in transport accident	0.717	0.283
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.717	0.283
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.717	0.283
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.717	0.283
C40-C41 Malignant neoplasms of bone and articular cartilage	0.716	0.284
X40-X49 Accidental poisoning by and exposure to noxious substances	0.715	0.284
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.715	0.285
G56 Mononeuropathies of upper limb	0.714	0.286
Q38-Q45 Other congenital malformations of the digestive system	0.713	0.287
J86.0 Pyothorax with fistula	0.712	0.288
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.712	0.288
C95 Leukaemia of unspecified cell type	0.712	0.288
C94 Other leukaemias of specified cell type	0.712	0.288
C93 Monocytic leukaemia	0.712	0.288
C86 Other specified types of T/NK-cell lymphoma	0.712	0.288
C84 Peripheral and cutaneous T-cell lymphomas	0.712	0.288
O71 Other obstetric trauma	0.710	0.289
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.710	0.290
G44 Other headache syndromes	0.710	0.290
C32.9 Larynx, unspecified	0.710	0.290
J02 Acute pharyngitis	0.709	0.290
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.708	0.291
C38 Malignant neoplasm of heart, mediastinum and pleura	0.708	0.291
C31 Malignant neoplasm of accessory sinuses	0.708	0.291
C37 Malignant neoplasm of thymus	0.708	0.291
C33 Malignant neoplasm of trachea	0.708	0.291
D75.2 Essential thrombocytosis	0.708	0.292
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.708	0.292
A65-A69 Other spirochaetal diseases	0.707	0.292
C55 Malignant neoplasm of uterus, part unspecified	0.707	0.293
X50-X57 Overexertion, travel and privation	0.707	0.293
Y59 Other and unspecified vaccines and biological substances	0.706	0.294
Y58 Bacterial vaccines	0.706	0.294
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.706	0.294
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.706	0.294
Y53 Agents primarily affecting the gastro-intestinal system	0.706	0.294
Y50 Central nervous system stimulants, not elsewhere classified	0.706	0.294
V20-V29 Motorcycle rider injured in transport accident	0.703	0.297
B65-B83 Helminthiases	0.703	0.297
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.703	0.297
C50.6 Axillary tail of breast	0.702	0.298
Y42.0 Glucocorticoids and synthetic analogs	0.702	0.298
G53 Cranial nerve disorders in diseases classified elsewhere	0.700	0.300
W16 Diving or jumping into water causing injury other than drowning or submersion	0.700	0.300
W15 Fall from cliff	0.700	0.300
W14 Fall from tree	0.700	0.300
W12 Fall on and from scaffolding	0.700	0.300
W11 Fall on and from ladder	0.700	0.300
W09 Fall involving playground equipment	0.700	0.300
W05 Fall involving wheelchair	0.700	0.300
W04 Fall while being carried or supported by other persons	0.700	0.300
W03 Other fall on same level due to collision with, or pushing by, another person	0.700	0.300
W01 Fall on same level from slipping, tripping and stumbling	0.700	0.300
W00 Fall on same level involving ice and snow	0.700	0.300
G52 Disorders of other cranial nerves	0.698	0.301
G46 Vascular syndromes of brain in cerebrovascular diseases	0.698	0.302
G47.2 Disorders of the sleep-wake schedule	0.696	0.304
O20-O29 Other maternal disorders predominantly related to pregnancy	0.695	0.305
Y49 Psychotropic drugs, not elsewhere classified	0.695	0.305
J03.9 Acute tonsillitis, unspecified	0.693	0.307
C83.3 Large cell (diffuse)	0.693	0.307
N08 Glomerular disorders in diseases classified elsewhere	0.693	0.307
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.692	0.308
D73 Diseases of spleen	0.691	0.308
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.692	0.308
A49 Bacterial infection of unspecified site	0.691	0.309
B59 Pneumocystosis	0.691	0.309
D67 Hereditary factor IX deficiency	0.689	0.311
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.689	0.311
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified	0.689	0.311
G58.8 Other specified mononeuropathies	0.689	0.311
C34.8 Overlapping lesion of bronchus and lung	0.688	0.312
G41 Status epilepticus	0.687	0.312
G94 Other disorders of brain in diseases classified elsewhere	0.687	0.312
G98 Other disorders of nervous system, not elsewhere classified	0.687	0.312
G92 Toxic encephalopathy	0.687	0.312
N11 Chronic tubulo-interstitial nephritis	0.686	0.314
G96.0 Cerebrospinal fluid leak	0.684	0.316
N18.8 Other chronic renal failure	0.684	0.316
Y91 Evidence of alcohol involvement determined by level of intoxication	0.684	0.316
Y90 Evidence of alcohol involvement determined by blood alcohol level	0.684	0.316
Y98 Lifestyle-related condition	0.684	0.316
Y97 Environmental-pollution-related condition	0.684	0.316
Y96 Work-related condition	0.684	0.316
N60.0 Solitary cyst of breast	0.683	0.317
D74 Methaemoglobinaemia	0.682	0.318
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.682	0.318
D71 Functional disorders of polymorphonuclear neutrophils	0.682	0.318
J20.9 Acute bronchitis, unspecified	0.682	0.318
D68.6 Other Thrombophilia	0.681	0.319
A46 Erysipelas	0.681	0.319
O74 Complications of anaesthesia during labour and delivery	0.680	0.319
O65 Obstructed labour due to maternal pelvic abnormality	0.680	0.319
O60 Preterm delivery	0.680	0.319
Q28 Other congenital malformations of circulatory system	0.680	0.320
G57.3 Lesion of lateral popliteal nerve	0.680	0.320
Q80-Q89 Other congenital malformations	0.679	0.321
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.679	0.321
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.679	0.321
O97 Death from sequelae of direct obstetric causes	0.679	0.321
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.679	0.321
O95 Obstetric death of unspecified cause	0.679	0.321
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.679	0.321
O72.3 Postpartum coagulation defects	0.678	0.321
O66 Other obstructed labour	0.678	0.322
Y42.7 Androgens and anabolic congeners	0.678	0.322
Y48.4 Anaesthetic, unspecified	0.677	0.323
C90.0 Multiple myeloma	0.677	0.323
O82 Single delivery by Caesarean section	0.677	0.323
W19.8 Other specified place	0.676	0.324
W19.5 Trade and service area	0.676	0.324
W19.0 Home	0.676	0.324
W19.7 Farm	0.676	0.324
W19.6 Industrial and construction area	0.676	0.324
O64 Obstructed labour due to malposition and malpresentation of foetus	0.676	0.324
G91 Hydrocephalus	0.675	0.325
J85 Abscess of lung and mediastinum	0.675	0.325
Y43.4 Immunosuppressive agents	0.675	0.325
N22 Calculus of urinary tract in diseases classified elsewhere	0.674	0.325
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.673	0.326
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.673	0.326
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.671	0.328
C85.1 B-cell lymphoma, unspecified	0.671	0.329
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.671	0.329
C81.1 Nodular sclerosis	0.671	0.329
W13.9 Unspecified place	0.671	0.329
C49.2 Connective and soft tissue of lower limb, including hip	0.669	0.331
N60.4 Mammary duct ectasia	0.669	0.331
G01 Meningitis in bacterial diseases classified elsewhere	0.668	0.332
D55-D59 Haemolytic anaemias	0.667	0.333
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.666	0.334
N07 Hereditary nephropathy, not elsewhere classified	0.664	0.336
N06 Isolated proteinuria with specified morphological lesion	0.664	0.336
N01 Rapidly progressive nephritic syndrome	0.664	0.336
N00 Acute nephritic syndrome	0.664	0.336
N13.7 Vesicoureteral-reflux-associated uropathy	0.662	0.338
N17.8 Other acute renal failure	0.662	0.338
N17.2 Acute renal failure with medullary necrosis	0.662	0.338
N17.1 Acute renal failure with acute cortical necrosis	0.662	0.338
N21.0 Calculus in bladder	0.662	0.338
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.662	0.338
G93.4 Encephalopathy, unspecified	0.661	0.339
C56 Malignant neoplasm of ovary	0.660	0.340
B85-B89 Pediculosis, acariasis and other infestations	0.660	0.340
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.660	0.340
A75-A79 Rickettsioses	0.660	0.340
A70-A74 Other diseases caused by chlamydiae	0.660	0.340
A20-A28 Certain zoonotic bacterial diseases	0.660	0.340
X20-X29 Contact with venomous animals and plants	0.659	0.340
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.657	0.343
J12 Viral pneumonia, not elsewhere classified	0.657	0.343
J09 Influenza due to certain identified influenza virus	0.657	0.343
G09 Sequelae of inflammatory diseases of central nervous system	0.657	0.343
C64-C68 Malignant neoplasms of urinary tract	0.656	0.344
B15-B19 Viral hepatitis	0.656	0.344
G90.9 Disorder of autonomic nervous system, unspecified	0.656	0.344
D68.0 Von Willebrand's disease	0.656	0.344
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.655	0.345
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.655	0.345
C30.0 Nasal cavity	0.655	0.345
C51 Malignant neoplasm of vulva	0.653	0.347
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.653	0.347
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.652	0.348
J15.7 Pneumonia due to Mycoplasma pneumoniae	0.652	0.348
D60-D64 Aplastic and other anaemias	0.652	0.348
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.651	0.348
Q35-Q37 Cleft lip and cleft palate	0.651	0.348
Q30-Q34 Congenital malformations of the respiratory system	0.651	0.348
N17.0 Acute renal failure with tubular necrosis	0.651	0.349
N18.1 Chronic kidney disease, stage 1	0.651	0.349
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.651	0.349
D72 Other disorders of white blood cells	0.651	0.349
O81 Single delivery by forceps and vacuum extractor	0.649	0.351
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.649	0.351
B99-B99 Other infectious diseases	0.647	0.353
G58.7 Mononeuritis multiplex	0.647	0.353
G58.0 Intercostal neuropathy	0.647	0.353
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.647	0.353
C57 Malignant neoplasm of other and unspecified female genital organs	0.646	0.354
D86 Sarcoidosis	0.646	0.354
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.645	0.355
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.645	0.355
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.645	0.355
D68.4 Acquired coagulation factor deficiency	0.644	0.355
D68.1 Hereditary factor XI deficiency	0.644	0.355
W19.4 Street and highway	0.644	0.356
B90-B94 Sequelae of infectious and parasitic diseases	0.644	0.356
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.643	0.356
C82.2 Large cell, follicular	0.643	0.357
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.642	0.358
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.642	0.358
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.642	0.358
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.642	0.358
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.642	0.358
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.642	0.358
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.642	0.358
Y51.1 Other parasympathomimetics [cholinergics]	0.642	0.358
Y51.0 Anticholinesterase agents	0.642	0.358
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.642	0.358
Q00-Q07 Congenital malformations of the nervous system	0.641	0.359
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.640	0.360
B25-B34 Other viral diseases	0.639	0.360
J17.2 Pneumonia in mycoses	0.638	0.362
N13.9 Obstructive and reflux uropathy, unspecified	0.638	0.362
G59.0 Diabetic mononeuropathy	0.637	0.363
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.637	0.363
N03.9 Unspecified	0.637	0.363
A44 Bartonellosis	0.636	0.364
A43 Nocardiosis	0.636	0.364
A42 Actinomycosis	0.636	0.364
A39 Meningococcal infection	0.636	0.364
A37 Whooping cough	0.636	0.364
A36 Diphtheria	0.636	0.364
A32 Listeriosis	0.636	0.364
A31 Infection due to other mycobacteria	0.636	0.364
A30 Leprosy [Hansen's disease]	0.636	0.364
A38 Scarlet fever	0.636	0.364
A35 Other tetanus	0.636	0.364
A34 Obstetrical tetanus	0.636	0.364
A33 Tetanus neonatorum	0.636	0.364
O16 Unspecified maternal hypertension	0.636	0.364
C32.8 Overlapping lesion of larynx	0.635	0.364
C32.3 Laryngeal cartilage	0.635	0.364
C32.2 Subglottis	0.635	0.364
C32.1 Supraglottis	0.635	0.364
G80-G83 Cerebral palsy and other paralytic syndromes	0.635	0.365
N60.2 Fibroadenosis of breast	0.635	0.365
A80-A89 Viral infections of the central nervous system	0.634	0.365
R06 Abnormalities of breathing	0.633	0.367
C83.7 Burkitt's tumour	0.632	0.368
C83.6 Undifferentiated (diffuse)	0.632	0.368
C83.5 Lymphoblastic (diffuse)	0.632	0.368
C83.4 Immunoblastic (diffuse)	0.632	0.368
C83.2 Mixed small and large cell (diffuse)	0.632	0.368
C83.1 Small cleaved cell (diffuse)	0.632	0.368
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.632	0.368
Y43.1 Antineoplastic antimetabolites	0.630	0.370
J05 Acute obstructive laryngitis [croup] and epiglottitis	0.630	0.370
O85 Puerperal sepsis	0.630	0.370
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.629	0.371
Q27 Other congenital malformations of peripheral vascular system	0.629	0.371
A40 Streptococcal septicaemia	0.628	0.372
J04 Acute laryngitis and tracheitis	0.628	0.372
D75.8 Other specified diseases of blood and blood-forming organs	0.628	0.372
G93.7 Reye's syndrome	0.628	0.372
G93.5 Compression of brain	0.628	0.372
W17.9 Unspecified place	0.627	0.372
W17.8 Other specified place	0.627	0.372
W17.0 Home	0.627	0.372
W17.7 Farm	0.627	0.372
W17.6 Industrial and construction area	0.627	0.372
W17.3 Sports and athletics area	0.627	0.372
W17.2 School, other institution and public administrative area	0.627	0.372
W17.1 Residential institution	0.627	0.372
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.627	0.373
N15 Other renal tubulo-interstitial diseases	0.627	0.373
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.627	0.373
G45 Transient cerebral ischaemic attacks and related syndromes	0.627	0.373
J15.1 Pneumonia due to Pseudomonas	0.626	0.374
G06.1 Intraspinal abscess and granuloma	0.625	0.375
Y48.5 Therapeutic gases	0.625	0.375
Y48.1 Parenteral anaesthetics	0.625	0.375
Y48.0 Inhaled anaesthetics	0.625	0.375
C71.9 Brain, unspecified	0.625	0.375
G57.9 Mononeuropathy of lower limb, unspecified	0.623	0.376
G57.5 Tarsal tunnel syndrome	0.623	0.376
G57.4 Lesion of medial popliteal nerve	0.623	0.376
G57.2 Lesion of femoral nerve	0.623	0.376
G57.1 Meralgia paraesthetica	0.623	0.376
G57.0 Lesion of sciatic nerve	0.623	0.376
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.623	0.377
Y48.3 Local anaesthetics	0.623	0.377
N02.9 Unspecified	0.623	0.377
G51 Facial nerve disorders	0.622	0.378
A16 Respiratory tuberculosis, not confirmed bacteriologically or histologically	0.621	0.379
C88.0 Waldenstrom's macroglobulinaemia	0.621	0.379
W02 Fall involving ice-skates, skis, roller-skates or skateboards	0.620	0.380
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.620	0.380
Y04 Assault by bodily force	0.619	0.380
B37 Candidiasis	0.619	0.381
A48 Other bacterial diseases, not elsewhere classified	0.619	0.381
Y40 Systemic antibiotics	0.619	0.381
G30-G32 Other degenerative diseases of the nervous system	0.619	0.381
B24 Unspecified human immunodeficiency virus [HIV] disease	0.619	0.381
R06.0 Dyspnoea	0.619	0.381
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system	0.619	0.381
C46 Kaposi's sarcoma	0.619	0.381
C92.4 Acute promyelocytic leukaemia	0.618	0.381
C81.7 Other Hodgkin's disease	0.618	0.382
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.618	0.382
C81.3 Lymphocytic depletion	0.618	0.382
C81.2 Mixed cellularity	0.618	0.382
C81.0 Lymphocytic predominance	0.618	0.382
Y42.5 Other oestrogens and progestogens	0.617	0.383
J84 Other interstitial pulmonary diseases	0.617	0.383

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations