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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs72759465
log Bayes Factor = 7.31467
Chromosome 1   position 244,867,747  (GRCh37) Explore rs72759465 on Ensembl!
Variant rs72759465 is part of Cluster X0020

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
I25.8 Other forms of chronic ischaemic heart disease
1.000 0.000 0.000
# Top node
0.999 0.001 0.000
Chapter X Diseases of the respiratory system
0.996 0.004 0.000
I35 Nonrheumatic aortic valve disorders
0.993 0.007 0.000
I25.2 Old myocardial infarction
0.991 0.009 0.000
Chapter II Neoplasms
0.977 0.023 0.000
I45 Other conduction disorders
0.972 0.028 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.972 0.028 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.967 0.033 0.000
J09-J18 Influenza and pneumonia
0.966 0.034 0.000
I51 Complications and ill-defined descriptions of heart disease
0.960 0.040 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.952 0.048 0.000
C79 Secondary malignant neoplasm of other sites
0.952 0.048 0.000
J18 Pneumonia, organism unspecified
0.947 0.053 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.940 0.060 0.000
C92 Myeloid leukaemia
0.937 0.063 0.000
I35.0 Aortic (valve) stenosis
0.936 0.064 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.934 0.066 0.000
J00-J06 Acute upper respiratory infections
0.933 0.067 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.933 0.067 0.000
Chapter XX External causes of morbidity and mortality
0.930 0.070 0.000
I45.1 Other and unspecified right bundle-branch block
0.925 0.075 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.921 0.079 0.000
I35.1 Aortic (valve) insufficiency
0.921 0.079 0.000
I51.8 Other ill-defined heart diseases
0.915 0.085 0.000
J30-J39 Other diseases of upper respiratory tract
0.908 0.092 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.903 0.097 0.000
J34 Other disorders of nose and nasal sinuses
0.902 0.098 0.000
I27 Other pulmonary heart diseases
0.889 0.111 0.000
I44 Atrioventricular and left bundle-branch block
0.881 0.119 0.000
J34.2 Deviated nasal septum
0.880 0.120 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.879 0.121 0.000
I74 Arterial embolism and thrombosis
0.877 0.123 0.000
I51.4 Myocarditis, unspecified
0.875 0.125 0.000
C79.2 Secondary malignant neoplasm of skin
0.874 0.126 0.000
J95-J99 Other diseases of the respiratory system
0.874 0.126 0.000
S40-S49 Injuries to the shoulder and upper arm
0.873 0.127 0.000
Chapter I Certain infectious and parasitic diseases
0.868 0.132 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.867 0.133 0.000
J00 Acute nasopharyngitis [common cold]
0.864 0.136 0.000
J20-J22 Other acute lower respiratory infections
0.864 0.136 0.000
J18.1 Lobar pneumonia, unspecified
0.862 0.138 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.861 0.139 0.000
S20-S29 Injuries to the thorax
0.860 0.140 0.000
I50 Heart failure
0.859 0.141 0.000
I27.2 Other secondary pulmonary hypertension
0.859 0.141 0.000
C64-C68 Malignant neoplasms of urinary tract
0.859 0.141 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.857 0.143 0.000
C92.0 Acute myeloid leukaemia
0.857 0.143 0.000
J18.9 Pneumonia, unspecified
0.854 0.146 0.000
J34.3 Hypertrophy of nasal turbinates
0.854 0.146 0.000
I22 Subsequent myocardial infarction
0.853 0.147 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.851 0.149 0.000
I44.2 Atrioventricular block, complete
0.849 0.151 0.000
I45.8 Other specified conduction disorders
0.844 0.156 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.843 0.157 0.000
Chapter XXII Codes for special purposes
0.836 0.164 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.836 0.164 0.000
I25.5 Ischaemic cardiomyopathy
0.834 0.166 0.000
C92.1 Chronic myeloid leukaemia
0.826 0.174 0.000
A30-A49 Other bacterial diseases
0.824 0.176 0.000
J18.0 Bronchopneumonia, unspecified
0.821 0.179 0.000
S50-S59 Injuries to the elbow and forearm
0.820 0.180 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.819 0.181 0.000
I10-I15 Hypertensive diseases
0.818 0.182 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.812 0.188 0.000
C67 Malignant neoplasm of bladder
0.811 0.189 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.804 0.196 0.000
I36 Nonrheumatic tricuspid valve disorders
0.801 0.199 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.799 0.201 0.000
I49 Other cardiac arrhythmias
0.797 0.203 0.000
S90-S99 Injuries to the ankle and foot
0.794 0.206 0.000
T92 Sequelae of injuries of upper limb
0.792 0.208 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.792 0.208 0.000
I35.9 Aortic valve disorder, unspecified
0.791 0.209 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.790 0.210 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.788 0.212 0.000
I50.0 Congestive heart failure
0.788 0.212 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.787 0.213 0.000
J98 Other respiratory disorders
0.784 0.216 0.000
W00-W19 Falls
0.784 0.216 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.781 0.219 0.000
J06.9 Acute upper respiratory infection, unspecified
0.778 0.222 0.000
C51-C58 Malignant neoplasms of female genital organs
0.775 0.225 0.000
Q60-Q64 Congenital malformations of the urinary system
0.771 0.229 0.000
I12 Hypertensive renal disease
0.770 0.230 0.000
I60-I69 Cerebrovascular diseases
0.768 0.232 0.000
I47 Paroxysmal tachycardia
0.768 0.232 0.000
V20-V29 Motorcycle rider injured in transport accident
0.767 0.233 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.767 0.233 0.000
C92.4 Acute promyelocytic leukaemia
0.766 0.233 0.000
I78 Diseases of capillaries
0.765 0.235 0.000
A80-A89 Viral infections of the central nervous system
0.765 0.235 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.764 0.236 0.000
S31 Open wound of abdomen, lower back and pelvis
0.759 0.241 0.000
I51.0 Cardiac septal defect, acquired
0.759 0.241 0.000
Chapter VI Diseases of the nervous system
0.758 0.242 0.000
I45.2 Bifascicular block
0.757 0.243 0.000
I45.3 Trifascicular block
0.757 0.243 0.000
A41 Other septicaemia
0.756 0.244 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.755 0.245 0.000
J98.4 Other disorders of lung
0.754 0.246 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.754 0.246 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.753 0.247 0.000
I33 Acute and subacute endocarditis
0.752 0.248 0.000
I24 Other acute ischaemic heart diseases
0.751 0.249 0.000
E50-E64 Other nutritional deficiencies
0.751 0.249 0.000
I38 Endocarditis, valve unspecified
0.751 0.249 0.000
S27 Injury of other and unspecified intrathoracic organs
0.751 0.249 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.747 0.253 0.000
Y10-Y34 Event of undetermined intent
0.747 0.253 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.746 0.254 0.000
J22 Unspecified acute lower respiratory infection
0.746 0.254 0.000
Q00-Q07 Congenital malformations of the nervous system
0.745 0.255 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.744 0.256 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.743 0.257 0.000
I45.4 Nonspecific intraventricular block
0.743 0.257 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.741 0.259 0.000
I49.9 Cardiac arrhythmia, unspecified
0.738 0.262 0.000
S40 Superficial injury of shoulder and upper arm
0.737 0.263 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.735 0.265 0.000
S70-S79 Injuries to the hip and thigh
0.734 0.266 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.734 0.266 0.000
E20-E35 Disorders of other endocrine glands
0.733 0.267 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.732 0.268 0.000
I27.8 Other specified pulmonary heart diseases
0.730 0.270 0.000
I73 Other peripheral vascular diseases
0.729 0.271 0.000
J81 Pulmonary oedema
0.728 0.272 0.000
I71 Aortic aneurysm and dissection
0.727 0.273 0.000
J14 Pneumonia due to Haemophilus influenzae
0.724 0.276 0.000
C91 Lymphoid leukaemia
0.723 0.277 0.000
C85.1 B-cell lymphoma, unspecified
0.722 0.278 0.000
I12.0 Hypertensive renal disease with renal failure
0.721 0.279 0.000
I72 Other aneurysm
0.721 0.279 0.000
C07 Malignant neoplasm of parotid gland
0.720 0.280 0.000
C82.0 Small cleaved cell, follicular
0.718 0.282 0.000
X20-X29 Contact with venomous animals and plants
0.718 0.282 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.716 0.284 0.000
I44.3 Other and unspecified atrioventricular block
0.716 0.284 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.715 0.285 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.714 0.286 0.000
M86-M90 Other osteopathies
0.714 0.286 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.713 0.287 0.000
X60-X84 Intentional self-harm
0.713 0.287 0.000
Q50-Q56 Congenital malformations of genital organs
0.712 0.288 0.000
S29 Other and unspecified injuries of thorax
0.712 0.288 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.711 0.289 0.000
T00-T07 Injuries involving multiple body regions
0.709 0.291 0.000
E55 Vitamin D deficiency
0.707 0.293 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.706 0.294 0.000
I51.6 Cardiovascular disease, unspecified
0.704 0.296 0.000
V40-V49 Car occupant injured in transport accident
0.704 0.296 0.000
J01 Acute sinusitis
0.704 0.296 0.000
I45.5 Other specified heart block
0.702 0.298 0.000
T91 Sequelae of injuries of neck and trunk
0.701 0.299 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.701 0.299 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.700 0.300 0.000
C67.3 Anterior wall of bladder
0.700 0.300 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.698 0.302 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.698 0.302 0.000
G90-G99 Other disorders of the nervous system
0.698 0.302 0.000
Y00-Y09 Assault
0.698 0.302 0.000
S43.0 Dislocation of shoulder joint
0.697 0.303 0.000
I45.0 Right fascicular block
0.697 0.303 0.000
T33-T35 Frostbite
0.697 0.303 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.697 0.303 0.000
I25.1 Atherosclerotic heart disease
0.696 0.304 0.000
M40-M43 Deforming dorsopathies
0.695 0.305 0.000
I25.3 Aneurysm of heart
0.695 0.305 0.000
W50-W64 Exposure to animate mechanical forces
0.694 0.306 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.693 0.306 0.000
C95 Leukaemia of unspecified cell type
0.693 0.306 0.000
C94 Other leukaemias of specified cell type
0.693 0.306 0.000
C93 Monocytic leukaemia
0.693 0.306 0.000
C88 Malignant immunoproliferative diseases
0.693 0.306 0.000
C86 Other specified types of T/NK-cell lymphoma
0.693 0.306 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.693 0.306 0.000
C04 Malignant neoplasm of floor of mouth
0.693 0.306 0.000
J17 Pneumonia in diseases classified elsewhere
0.693 0.307 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.693 0.307 0.000
J12 Viral pneumonia, not elsewhere classified
0.693 0.307 0.000
J09 Influenza due to certain identified influenza virus
0.693 0.307 0.000
J11 Influenza, virus not identified
0.692 0.308 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.692 0.308 0.000
T92.1 Sequelae of fracture of arm
0.691 0.309 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.691 0.309 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.689 0.311 0.000
I51.5 Myocardial degeneration
0.688 0.312 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.688 0.312 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.688 0.312 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.688 0.312 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.686 0.314 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.683 0.317 0.000
C67.6 Ureteric orifice
0.682 0.317 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.682 0.317 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.682 0.317 0.000
I47.2 Ventricular tachycardia
0.682 0.318 0.000
C79.6 Secondary malignant neoplasm of ovary
0.681 0.318 0.000
A40 Streptococcal septicaemia
0.681 0.319 0.000
I70 Atherosclerosis
0.681 0.319 0.000
I44.6 Other and unspecified fascicular block
0.681 0.319 0.000
C67.4 Posterior wall of bladder
0.681 0.319 0.000
A46 Erysipelas
0.680 0.320 0.000
S41 Open wound of shoulder and upper arm
0.680 0.320 0.000
J18.8 Other pneumonia, organism unspecified
0.679 0.321 0.000
J18.2 Hypostatic pneumonia, unspecified
0.679 0.321 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.679 0.321 0.000
I49.4 Other and unspecified premature depolarisation
0.678 0.322 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.676 0.324 0.000
S10-S19 Injuries to the neck
0.676 0.324 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.675 0.325 0.000
E55.9 Vitamin D deficiency, unspecified
0.675 0.325 0.000
J10 Influenza due to identified influenza virus
0.674 0.325 0.000
I67 Other cerebrovascular diseases
0.674 0.326 0.000
S27.0 Traumatic pneumothorax
0.674 0.326 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.673 0.327 0.000
S43.4 Sprain and strain of shoulder joint
0.673 0.327 0.000
B65-B83 Helminthiases
0.672 0.328 0.000
C92.9 Myeloid leukaemia, unspecified
0.672 0.328 0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia
0.672 0.328 0.000
C92.7 Other myeloid leukaemia
0.672 0.328 0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality
0.672 0.328 0.000
C92.5 Acute myelomonocytic leukaemia
0.672 0.328 0.000
C92.3 Myeloid sarcoma
0.672 0.328 0.000
C92.2 Subacute myeloid leukaemia
0.672 0.328 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.671 0.329 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.670 0.330 0.000
Y84.0 Cardiac catheterisation
0.670 0.330 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.669 0.331 0.000
X50-X57 Overexertion, travel and privation
0.669 0.331 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.669 0.331 0.000
Q35-Q37 Cleft lip and cleft palate
0.669 0.331 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.669 0.331 0.000
J20 Acute bronchitis
0.667 0.333 0.000
Y35-Y36 Legal intervention and operations of war
0.667 0.333 0.000
X85-X99 Assault
0.667 0.333 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.667 0.333 0.000
X30-X39 Exposure to forces of nature
0.667 0.333 0.000
X10-X19 Contact with heat and hot substances
0.667 0.333 0.000
X00-X09 Exposure to smoke, fire and flames
0.667 0.333 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.667 0.333 0.000
W75-W84 Other accidental threats to breathing
0.667 0.333 0.000
W65-W74 Accidental drowning and submersion
0.667 0.333 0.000
V98-V99 Other and unspecified transport accidents
0.667 0.333 0.000
V95-V97 Air and space transport accidents
0.667 0.333 0.000
V90-V94 Water transport accidents
0.667 0.333 0.000
V70-V79 Bus occupant injured in transport accident
0.667 0.333 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.667 0.333 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.667 0.333 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.667 0.333 0.000
V01-V09 Pedestrian injured in transport accident
0.667 0.333 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.667 0.333 0.000
M43 Other deforming dorsopathies
0.665 0.335 0.000
C53 Malignant neoplasm of cervix uteri
0.664 0.336 0.000
I73.9 Peripheral vascular disease, unspecified
0.663 0.337 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.662 0.338 0.000
E23 Hypofunction and other disorders of pituitary gland
0.662 0.338 0.000
V80-V89 Other land transport accidents
0.662 0.338 0.000
I74.8 Embolism and thrombosis of other arteries
0.661 0.339 0.000
I28 Other diseases of pulmonary vessels
0.661 0.339 0.000
I46 Cardiac arrest
0.660 0.340 0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.658 0.341 0.000
G95 Other diseases of spinal cord
0.658 0.342 0.000
C66 Malignant neoplasm of ureter
0.658 0.342 0.000
I34 Nonrheumatic mitral valve disorders
0.658 0.342 0.000
S51 Open wound of forearm
0.657 0.343 0.000
T92.2 Sequelae of fracture at wrist and hand level
0.656 0.344 0.000
Q61 Cystic kidney disease
0.655 0.345 0.000
J37 Chronic laryngitis and laryngotracheitis
0.655 0.345 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.655 0.345 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.655 0.345 0.000
S91 Open wound of ankle and foot
0.653 0.347 0.000
T79-T79 Certain early complications of trauma
0.652 0.348 0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van
0.651 0.349 0.000
C80 Malignant neoplasm without specification of site
0.650 0.350 0.000
B35-B49 Mycoses
0.650 0.350 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.649 0.351 0.000
Y95 Nosocomial condition
0.649 0.351 0.000
I50.1 Left ventricular failure
0.649 0.351 0.000
E00-E07 Disorders of thyroid gland
0.648 0.352 0.000
J34.1 Cyst and mucocele of nose and nasal sinus
0.647 0.353 0.000
J34.0 Abscess, furuncle and carbuncle of nose
0.647 0.353 0.000
S31.8 Open wound of other and unspecified parts of abdomen
0.646 0.354 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.646 0.354 0.000
T14 Injury of unspecified body region
0.645 0.354 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.645 0.355 0.000
W18 Other fall on same level
0.644 0.356 0.000
Q43 Other congenital malformations of intestine
0.643 0.357 0.000
A86 Unspecified viral encephalitis
0.643 0.357 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.642 0.358 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.640 0.360 0.000
T20 Burn and corrosion of head and neck
0.640 0.360 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.640 0.360 0.000
I05-I09 Chronic rheumatic heart diseases
0.638 0.362 0.000
I61 Intracerebral haemorrhage
0.638 0.362 0.000
B99-B99 Other infectious diseases
0.638 0.362 0.000
I27.1 Kyphoscoliotic heart disease
0.637 0.363 0.000
E10-E14 Diabetes mellitus
0.637 0.363 0.000
M43.1 Spondylolisthesis
0.636 0.364 0.000
Q80-Q89 Other congenital malformations
0.636 0.364 0.000
S92 Fracture of foot, except ankle
0.636 0.364 0.000
M90 Osteopathies in diseases classified elsewhere
0.635 0.364 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.633 0.366 0.000
S60-S69 Injuries to the wrist and hand
0.633 0.367 0.000
A87 Viral meningitis
0.633 0.367 0.000
S20 Superficial injury of thorax
0.632 0.368 0.000
S54 Injury of nerves at forearm level
0.632 0.368 0.000
I44.5 Left posterior fascicular block
0.632 0.368 0.000
I44.4 Left anterior fascicular block
0.632 0.368 0.000
C67.8 Overlapping lesion of bladder
0.630 0.370 0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.630 0.370 0.000
C82.6 Cutaneous follicle centre lymphoma
0.630 0.370 0.000
C82.5 Diffuse follicle centre lymphoma
0.630 0.370 0.000
C82.4 Follicular lymphoma grade IIIb
0.630 0.370 0.000
C82.3 Follicular lymphoma grade IIIa
0.630 0.370 0.000
C82.2 Large cell, follicular
0.630 0.370 0.000
C82.1 Mixed small cleaved and large cell, follicular
0.630 0.370 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.629 0.371 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.629 0.371 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.629 0.371 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.629 0.371 0.000
T13 Other injuries of lower limb, level unspecified
0.628 0.372 0.000
I27.0 Primary pulmonary hypertension
0.627 0.372 0.000
M60-M63 Disorders of muscles
0.627 0.373 0.000
J04 Acute laryngitis and tracheitis
0.627 0.373 0.000
J96 Respiratory failure, not elsewhere classified
0.627 0.373 0.000
S56 Injury of muscle and tendon at forearm level
0.626 0.373 0.000
J02 Acute pharyngitis
0.626 0.374 0.000
S48 Traumatic amputation of shoulder and upper arm
0.626 0.374 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.626 0.374 0.000
S44 Injury of nerves at shoulder and upper arm level
0.626 0.374 0.000
S47 Crushing injury of shoulder and upper arm
0.626 0.374 0.000
I78.1 Naevus, nonneoplastic
0.625 0.375 0.000
W19 Unspecified fall
0.624 0.376 0.000
U80 Agent resistant to penicillin and related antibiotics
0.623 0.377 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.622 0.377 0.000
B50-B64 Protozoal diseases
0.622 0.377 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.622 0.377 0.000
A75-A79 Rickettsioses
0.622 0.377 0.000
A70-A74 Other diseases caused by chlamydiae
0.622 0.377 0.000
A65-A69 Other spirochaetal diseases
0.622 0.377 0.000
A20-A28 Certain zoonotic bacterial diseases
0.622 0.377 0.000
A15-A19 Tuberculosis
0.622 0.377 0.000
C67.1 Dome of bladder
0.622 0.378 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.622 0.378 0.000
B15-B19 Viral hepatitis
0.620 0.379 0.000
I51.9 Heart disease, unspecified
0.620 0.380 0.000
S31.4 Open wound of vagina and vulva
0.620 0.380 0.000
C15-C26 Malignant neoplasms of digestive organs
0.620 0.380 0.000
J21 Acute bronchiolitis
0.619 0.381 0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)
0.619 0.381 0.000
I22.8 Subsequent myocardial infarction of other sites
0.619 0.381 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.619 0.381 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.618 0.382 0.000
J80 Adult respiratory distress syndrome
0.618 0.382 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.617 0.383 0.000
S37 Injury of urinary and pelvic organs
0.617 0.383 0.000
S36 Injury of intra-abdominal organs
0.617 0.383 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.617 0.383 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.617 0.383 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.617 0.383 0.000
Y84.4 Aspiration of fluid
0.617 0.383 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.617 0.383 0.000
S26 Injury of heart
0.617 0.383 0.000
S25 Injury of blood vessels of thorax
0.617 0.383 0.000
S24 Injury of nerves and spinal cord at thorax level
0.617 0.383 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.617 0.383 0.000
S21 Open wound of thorax
0.617 0.383 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.617 0.383 0.000
I12.9 Hypertensive renal disease without renal failure
0.617 0.383 0.000
T11 Other injuries of upper limb, level unspecified
0.616 0.384 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.616 0.384 0.000
S70 Superficial injury of hip and thigh
0.616 0.384 0.000
Q07 Other congenital malformations of nervous system
0.615 0.385 0.000
Y28 Contact with sharp object, undetermined intent
0.615 0.385 0.000
C56 Malignant neoplasm of ovary
0.615 0.385 0.000
T98 Sequelae of other and unspecified effects of external causes
0.615 0.385 0.000
T95 Sequelae of burns, corrosions and frostbite
0.615 0.385 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.615 0.385 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.615 0.385 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.615 0.385 0.000
A41.9 Septicaemia, unspecified
0.614 0.386 0.000
G40-G47 Episodic and paroxysmal disorders
0.613 0.387 0.000
I69 Sequelae of cerebrovascular disease
0.613 0.387 0.000
I71.0 Dissection of aorta [any part]
0.612 0.388 0.000
J60-J70 Lung diseases due to external agents
0.611 0.388 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.610 0.390 0.000
C13 Malignant neoplasm of hypopharynx
0.610 0.390 0.000
C11 Malignant neoplasm of nasopharynx
0.610 0.390 0.000
C10 Malignant neoplasm of oropharynx
0.610 0.390 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.610 0.390 0.000
C06 Malignant neoplasm of other and unspecified parts of mouth
0.610 0.390 0.000
C05 Malignant neoplasm of palate
0.610 0.390 0.000
C03 Malignant neoplasm of gum
0.610 0.390 0.000
C00 Malignant neoplasm of lip
0.610 0.390 0.000
C12 Malignant neoplasm of pyriform sinus
0.610 0.390 0.000
S40.0 Contusion of shoulder and upper arm
0.610 0.390 0.000
I74.5 Embolism and thrombosis of iliac artery
0.610 0.390 0.000
C81 Hodgkin's disease
0.609 0.391 0.000
I45.9 Conduction disorder, unspecified
0.609 0.391 0.000
J98.6 Disorders of diaphragm
0.609 0.391 0.000
T87 Complications peculiar to reattachment and amputation
0.607 0.393 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.606 0.394 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.606 0.394 0.000
C65 Malignant neoplasm of renal pelvis
0.606 0.394 0.000
S29.9 Unspecified injury of thorax
0.605 0.395 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.605 0.395 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.605 0.395 0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb
0.604 0.396 0.000
J06.8 Other acute upper respiratory infections of multiple sites
0.604 0.396 0.000
J06.0 Acute laryngopharyngitis
0.604 0.396 0.000
A48 Other bacterial diseases, not elsewhere classified
0.604 0.396 0.000
C67.5 Bladder neck
0.604 0.396 0.000
M86 Osteomyelitis
0.602 0.398 0.000
M43.16 Spondylolisthesis (Lumbar region)
0.602 0.398 0.000
T23 Burn and corrosion of wrist and hand
0.601 0.399 0.000
Y84.1 Kidney dialysis
0.601 0.399 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.600 0.400 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.599 0.400 0.000
G90 Disorders of autonomic nervous system
0.599 0.401 0.000
S50 Superficial injury of forearm
0.597 0.403 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.597 0.403 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.597 0.403 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.597 0.403 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.596 0.404 0.000
C73 Malignant neoplasm of thyroid gland
0.596 0.404 0.000
E65-E68 Obesity and other hyperalimentation
0.595 0.405 0.000
I45.6 Preexcitation syndrome
0.594 0.406 0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb
0.594 0.406 0.000
M89 Other disorders of bone
0.592 0.408 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.591 0.409 0.000
A44 Bartonellosis
0.591 0.409 0.000
A43 Nocardiosis
0.591 0.409 0.000
A42 Actinomycosis
0.591 0.409 0.000
A39 Meningococcal infection
0.591 0.409 0.000
A37 Whooping cough
0.591 0.409 0.000
A36 Diphtheria
0.591 0.409 0.000
A32 Listeriosis
0.591 0.409 0.000
A31 Infection due to other mycobacteria
0.591 0.409 0.000
A30 Leprosy [Hansen's disease]
0.591 0.409 0.000
A38 Scarlet fever
0.591 0.409 0.000
A35 Other tetanus
0.591 0.409 0.000
A34 Obstetrical tetanus
0.591 0.409 0.000
A33 Tetanus neonatorum
0.591 0.409 0.000
S99 Other and unspecified injuries of ankle and foot
0.590 0.410 0.000
I35.8 Other aortic valve disorders
0.590 0.410 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.589 0.410 0.000
I27.9 Pulmonary heart disease, unspecified
0.589 0.411 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.589 0.411 0.000
J15.7 Pneumonia due to Mycoplasma pneumoniae
0.589 0.411 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.588 0.412 0.000
E23.0 Hypopituitarism
0.588 0.412 0.000
S59 Other and unspecified injuries of forearm
0.588 0.412 0.000
S58 Traumatic amputation of forearm
0.588 0.412 0.000
S57 Crushing injury of forearm
0.588 0.412 0.000
S55 Injury of blood vessels at forearm level
0.588 0.412 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.588 0.412 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.588 0.412 0.000
I13 Hypertensive heart and renal disease
0.586 0.413 0.000
G95.2 Cord compression, unspecified
0.586 0.414 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.585 0.415 0.000
S80-S89 Injuries to the knee and lower leg
0.585 0.415 0.000
S43.1 Dislocation of acromioclavicular joint
0.585 0.415 0.000
E07 Other disorders of thyroid
0.585 0.415 0.000
C53.9 Cervix uteri, unspecified
0.585 0.415 0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.583 0.416 0.000
E28 Ovarian dysfunction
0.583 0.417 0.000
T09 Other injuries of spine and trunk, level unspecified
0.582 0.417 0.000
T12.X1 Fracture of lower limb, level unspecified (open)
0.582 0.417 0.000
T12.X0 Fracture of lower limb, level unspecified (closed)
0.582 0.417 0.000
T12 Fracture of lower limb, level unspecified
0.582 0.417 0.000
T10.X1 Fracture of upper limb, level unspecified (open)
0.582 0.417 0.000
T10.X0 Fracture of upper limb, level unspecified (closed)
0.582 0.417 0.000
T10 Fracture of upper limb, level unspecified
0.582 0.417 0.000
T08.X1 Fracture of spine, level unspecified (open)
0.582 0.417 0.000
T08.X0 Fracture of spine, level unspecified (closed)
0.582 0.417 0.000
T08 Fracture of spine, level unspecified
0.582 0.417 0.000
W10 Fall on and from stairs and steps
0.582 0.418 0.000
C67.7 Urachus
0.581 0.418 0.000
C67.0 Trigone of bladder
0.581 0.418 0.000
Q65 Congenital deformities of hip
0.581 0.419 0.000
C04.9 Floor of mouth, unspecified
0.580 0.419 0.000
S52 Fracture of forearm
0.580 0.420 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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