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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs59552706
log Bayes Factor = 7.80425
Chromosome 20   position 10,714,315  (GRCh37) Explore rs59552706 on Ensembl!
Variant rs59552706 is part of Cluster X0061

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.998 0.002 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.996 0.004 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.988 0.012 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.985 0.015 0.000
Chapter V Mental and behavioural disorders
0.975 0.025 0.000
M80-M85 Disorders of bone density and structure
0.974 0.026 0.000
M86-M90 Other osteopathies
0.972 0.028 0.000
I10 Essential (primary) hypertension
0.972 0.028 0.000
M45-M49 Spondylopathies
0.967 0.033 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.958 0.042 0.000
I10-I15 Hypertensive diseases
0.954 0.046 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.954 0.046 0.000
Chapter VIII Diseases of the ear and mastoid process
0.954 0.046 0.000
Chapter VI Diseases of the nervous system
0.952 0.048 0.000
S90-S99 Injuries to the ankle and foot
0.950 0.050 0.000
Chapter IX Diseases of the circulatory system
0.949 0.051 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.946 0.054 0.000
S32 Fracture of lumbar spine and pelvis
0.943 0.057 0.000
S70-S79 Injuries to the hip and thigh
0.937 0.063 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.937 0.063 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.930 0.070 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.927 0.073 0.000
M45 Ankylosing spondylitis
0.927 0.073 0.000
M46 Other inflammatory spondylopathies
0.927 0.073 0.000
Chapter I Certain infectious and parasitic diseases
0.925 0.075 0.000
H80-H83 Diseases of inner ear
0.924 0.076 0.000
M65-M68 Disorders of synovium and tendon
0.921 0.079 0.000
G20-G26 Extrapyramidal and movement disorders
0.918 0.082 0.000
Y45.0 Opioids and related analgesics
0.916 0.084 0.000
M89 Other disorders of bone
0.914 0.086 0.000
T40.2 Other opioids
0.913 0.087 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.913 0.087 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.912 0.088 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.911 0.089 0.000
W00-W19 Falls
0.910 0.090 0.000
H81 Disorders of vestibular function
0.899 0.101 0.000
O26.8 Other specified pregnancy-related conditions
0.899 0.101 0.000
M67 Other disorders of synovium and tendon
0.894 0.106 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.892 0.108 0.000
A30-A49 Other bacterial diseases
0.891 0.109 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.891 0.109 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.887 0.113 0.000
S80-S89 Injuries to the knee and lower leg
0.887 0.113 0.000
F60-F69 Disorders of adult personality and behaviour
0.886 0.114 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.884 0.116 0.000
Y40 Systemic antibiotics
0.884 0.116 0.000
G20 Parkinson's disease
0.882 0.118 0.000
M84 Disorders of continuity of bone
0.881 0.119 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.876 0.124 0.000
H81.1 Benign paroxysmal vertigo
0.875 0.125 0.000
T23 Burn and corrosion of wrist and hand
0.873 0.127 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.868 0.132 0.000
M81 Osteoporosis without pathological fracture
0.868 0.132 0.000
X60-X84 Intentional self-harm
0.867 0.133 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.865 0.135 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.865 0.135 0.000
A41 Other septicaemia
0.862 0.138 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.859 0.141 0.000
M67.8 Other specified disorders of synovium and tendon
0.854 0.146 0.000
M60-M63 Disorders of muscles
0.846 0.154 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.845 0.155 0.000
I89.0 Lymphoedema, not elsewhere classified
0.844 0.156 0.000
A41.9 Septicaemia, unspecified
0.843 0.157 0.000
F41 Other anxiety disorders
0.842 0.158 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.836 0.164 0.000
W18 Other fall on same level
0.835 0.165 0.000
S90 Superficial injury of ankle and foot
0.834 0.166 0.000
M89.8 Other specified disorders of bone
0.833 0.167 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.830 0.170 0.000
O24 Diabetes mellitus in pregnancy
0.828 0.172 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.824 0.176 0.000
F60 Specific personality disorders
0.822 0.178 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.821 0.179 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.819 0.181 0.000
F41.9 Anxiety disorder, unspecified
0.819 0.181 0.000
S92 Fracture of foot, except ankle
0.819 0.181 0.000
T40.6 Other and unspecified narcotics
0.813 0.187 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.812 0.188 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.812 0.188 0.000
G30-G32 Other degenerative diseases of the nervous system
0.810 0.190 0.000
M80 Osteoporosis with pathological fracture
0.808 0.192 0.000
M87 Osteonecrosis
0.806 0.193 0.000
H90-H95 Other disorders of ear
0.800 0.200 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.799 0.201 0.000
M90 Osteopathies in diseases classified elsewhere
0.798 0.202 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.797 0.203 0.000
I82 Other venous embolism and thrombosis
0.796 0.204 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.793 0.207 0.000
S72 Fracture of femur
0.793 0.207 0.000
S79 Other and unspecified injuries of hip and thigh
0.793 0.207 0.000
H60-H62 Diseases of external ear
0.792 0.208 0.000
T92 Sequelae of injuries of upper limb
0.790 0.210 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.786 0.213 0.000
I81 Portal vein thrombosis
0.786 0.214 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.785 0.215 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.785 0.215 0.000
W50-W64 Exposure to animate mechanical forces
0.784 0.216 0.000
T93 Sequelae of injuries of lower limb
0.783 0.217 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.783 0.217 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.781 0.219 0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis
0.781 0.219 0.000
Y45.1 Salicylates
0.781 0.219 0.000
S32.0 Fracture of lumbar vertebra
0.780 0.220 0.000
W07 Fall involving chair
0.780 0.220 0.000
Y40.0 Penicillins
0.778 0.222 0.000
T66-T78 Other and unspecified effects of external causes
0.776 0.224 0.000
Y52 Agents primarily affecting the cardiovascular system
0.776 0.224 0.000
E20-E35 Disorders of other endocrine glands
0.775 0.225 0.000
T23.0 Burn of unspecified degree of wrist and hand
0.773 0.227 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.773 0.227 0.000
S32.3 Fracture of ilium
0.772 0.228 0.000
V95-V97 Air and space transport accidents
0.771 0.229 0.000
O23 Infections of genito-urinary tract in pregnancy
0.771 0.229 0.000
S32.1 Fracture of sacrum
0.769 0.231 0.000
Y45.5 4-Aminophenol derivatives
0.769 0.231 0.000
S32.7 Multiple fractures of lumbar spine and pelvis
0.769 0.231 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.769 0.231 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.766 0.234 0.000
M70-M79 Other soft tissue disorders
0.766 0.234 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.765 0.235 0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)
0.765 0.235 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.764 0.236 0.000
Q80-Q89 Other congenital malformations
0.764 0.236 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.764 0.236 0.000
X20-X29 Contact with venomous animals and plants
0.763 0.237 0.000
S80 Superficial injury of lower leg
0.763 0.237 0.000
M00-M03 Infectious arthropathies
0.763 0.237 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.762 0.238 0.000
T23.3 Burn of third degree of wrist and hand
0.762 0.238 0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)
0.760 0.240 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.759 0.241 0.000
V80-V89 Other land transport accidents
0.759 0.241 0.000
G35 Multiple sclerosis
0.758 0.242 0.000
T20 Burn and corrosion of head and neck
0.757 0.243 0.000
T18 Foreign body in alimentary tract
0.756 0.244 0.000
B99-B99 Other infectious diseases
0.756 0.244 0.000
E27 Other disorders of adrenal gland
0.756 0.244 0.000
S71 Open wound of hip and thigh
0.756 0.244 0.000
M85 Other disorders of bone density and structure
0.755 0.245 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.755 0.245 0.000
S99 Other and unspecified injuries of ankle and foot
0.753 0.247 0.000
T90 Sequelae of injuries of head
0.751 0.249 0.000
V20-V29 Motorcycle rider injured in transport accident
0.749 0.251 0.000
W10 Fall on and from stairs and steps
0.749 0.251 0.000
M81.4 Drug-induced osteoporosis
0.749 0.251 0.000
M46.3 Infection of intervertebral disk (pyogenic)
0.748 0.252 0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.747 0.253 0.000
V40-V49 Car occupant injured in transport accident
0.746 0.254 0.000
O21 Excessive vomiting in pregnancy
0.746 0.254 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.745 0.255 0.000
T36 Poisoning by systemic antibiotics
0.745 0.255 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.743 0.257 0.000
M67.2 Synovial hypertrophy, not elsewhere classified
0.743 0.257 0.000
B35-B49 Mycoses
0.743 0.257 0.000
G24 Dystonia
0.742 0.258 0.000
S31 Open wound of abdomen, lower back and pelvis
0.741 0.259 0.000
I11 Hypertensive heart disease
0.740 0.260 0.000
F70-F79 Mental retardation
0.738 0.262 0.000
S32.5 Fracture of pubis
0.738 0.262 0.000
M62 Other disorders of muscle
0.737 0.263 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.736 0.264 0.000
M89.9 Disorder of bone, unspecified
0.735 0.265 0.000
Q60-Q64 Congenital malformations of the urinary system
0.733 0.267 0.000
I82.8 Embolism and thrombosis of other specified veins
0.733 0.267 0.000
F41.1 Generalised anxiety disorder
0.733 0.267 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.732 0.268 0.000
F44 Dissociative [conversion] disorders
0.732 0.268 0.000
T16 Foreign body in ear
0.731 0.269 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.731 0.269 0.000
M88 Paget's disease of bone [osteitis deformans]
0.731 0.269 0.000
Y48 Anaesthetics and therapeutic gases
0.731 0.269 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.731 0.269 0.000
I83 Varicose veins of lower extremities
0.729 0.271 0.000
Y53.1 Other antacids and anti-gastric-secretion drugs
0.728 0.272 0.000
W18.3 Sports and athletics area
0.727 0.272 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.726 0.274 0.000
Y00-Y09 Assault
0.725 0.275 0.000
T14 Injury of unspecified body region
0.725 0.275 0.000
F48 Other neurotic disorders
0.725 0.275 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.725 0.275 0.000
F60.3 Emotionally unstable personality disorder
0.725 0.275 0.000
Q00-Q07 Congenital malformations of the nervous system
0.724 0.276 0.000
F06.7 Mild cognitive disorder
0.724 0.276 0.000
M81.9 Osteoporosis, unspecified
0.724 0.276 0.000
S36 Injury of intra-abdominal organs
0.723 0.277 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.723 0.277 0.000
Y54.7 Agents affecting calcification
0.723 0.277 0.000
M89.0 Algoneurodystrophy
0.723 0.277 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.719 0.281 0.000
T95 Sequelae of burns, corrosions and frostbite
0.719 0.281 0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.718 0.282 0.000
T92.1 Sequelae of fracture of arm
0.718 0.282 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.717 0.282 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
B15-B19 Viral hepatitis
0.717 0.283 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.717 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.717 0.283 0.000
Y10-Y34 Event of undetermined intent
0.717 0.283 0.000
X85-X99 Assault
0.717 0.283 0.000
X30-X39 Exposure to forces of nature
0.717 0.283 0.000
X00-X09 Exposure to smoke, fire and flames
0.717 0.283 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.717 0.283 0.000
W75-W84 Other accidental threats to breathing
0.717 0.283 0.000
W65-W74 Accidental drowning and submersion
0.717 0.283 0.000
V98-V99 Other and unspecified transport accidents
0.717 0.283 0.000
V90-V94 Water transport accidents
0.717 0.283 0.000
V70-V79 Bus occupant injured in transport accident
0.717 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.717 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.717 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.717 0.283 0.000
V01-V09 Pedestrian injured in transport accident
0.717 0.283 0.000
W18.1 Residential institution
0.715 0.285 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.715 0.285 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.714 0.286 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.714 0.286 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.714 0.286 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.714 0.286 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.714 0.286 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.713 0.287 0.000
S32.4 Fracture of acetabulum
0.713 0.287 0.000
S86 Injury of muscle and tendon at lower leg level
0.713 0.287 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.712 0.288 0.000
H81.9 Disorder of vestibular function, unspecified
0.711 0.289 0.000
Y88 Sequelae of surgical and medical care as external cause
0.711 0.289 0.000
T47.1 Other antacids and anti-gastric-secretion drugs
0.711 0.289 0.000
M89.86 Other specified disorders of bone (Lower leg)
0.710 0.290 0.000
X10-X19 Contact with heat and hot substances
0.710 0.290 0.000
T91 Sequelae of injuries of neck and trunk
0.709 0.291 0.000
X68 Intentional self-poisoning by and exposure to pesticides
0.709 0.291 0.000
S39.8 Other specified injuries of abdomen, lower back and pelvis
0.709 0.291 0.000
Y59 Other and unspecified vaccines and biological substances
0.708 0.292 0.000
Y58 Bacterial vaccines
0.708 0.292 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.708 0.292 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.708 0.292 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.708 0.292 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.708 0.292 0.000
B50-B64 Protozoal diseases
0.708 0.292 0.000
H93 Other disorders of ear, not elsewhere classified
0.707 0.293 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.706 0.294 0.000
S37 Injury of urinary and pelvic organs
0.706 0.294 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.706 0.294 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.706 0.294 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.706 0.294 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.705 0.295 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.705 0.295 0.000
Y57 Other and unspecified drugs and medicaments
0.704 0.295 0.000
T21 Burn and corrosion of trunk
0.703 0.297 0.000
M84.4 Pathological fracture, not elsewhere classified
0.703 0.297 0.000
S10-S19 Injuries to the neck
0.703 0.297 0.000
F80-F89 Disorders of psychological development
0.703 0.297 0.000
I83.1 Varicose veins of lower extremities with inflammation
0.702 0.298 0.000
S90.3 Contusion of other and unspecified parts of foot
0.702 0.298 0.000
G70-G73 Diseases of myoneural junction and muscle
0.701 0.299 0.000
H92 Otalgia and effusion of ear
0.701 0.299 0.000
M86 Osteomyelitis
0.701 0.299 0.000
Y52.1 Calcium-channel blockers
0.700 0.300 0.000
A15-A19 Tuberculosis
0.699 0.301 0.000
M91-M94 Chondropathies
0.699 0.301 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.699 0.301 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.699 0.301 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.698 0.302 0.000
M83 Adult osteomalacia
0.698 0.302 0.000
O24.4 Diabetes mellitus arising in pregnancy
0.697 0.303 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.697 0.303 0.000
Y40.3 Macrolides
0.696 0.304 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.696 0.304 0.000
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)
0.696 0.304 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.695 0.304 0.000
F40 Phobic anxiety disorders
0.695 0.305 0.000
B94 Sequelae of other and unspecified infectious and parasitic diseases
0.694 0.306 0.000
M49 Spondylopathies in diseases classified elsewhere
0.693 0.307 0.000
O22 Venous complications in pregnancy
0.693 0.307 0.000
H83 Other diseases of inner ear
0.693 0.307 0.000
M82 Osteoporosis in diseases classified elsewhere
0.690 0.310 0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.690 0.310 0.000
S79.9 Unspecified injury of hip and thigh
0.689 0.311 0.000
Y54.8 Agents affecting uric acid metabolism
0.689 0.311 0.000
B44 Aspergillosis
0.688 0.312 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.687 0.313 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.687 0.313 0.000
T40.8 Lysergide [LSD]
0.687 0.313 0.000
T40.7 Cannabis (derivatives)
0.687 0.313 0.000
T40.5 Cocaine
0.687 0.313 0.000
T40.3 Methadone
0.687 0.313 0.000
T40.1 Heroin
0.687 0.313 0.000
T40.0 Opium
0.687 0.313 0.000
V10-V19 Pedal cyclist injured in transport accident
0.685 0.314 0.000
M67.1 Other contracture of tendon (sheath)
0.685 0.314 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.685 0.315 0.000
Y45.8 Other analgesics and antipyretics
0.685 0.315 0.000
M84.0 Malunion of fracture
0.684 0.316 0.000
I13 Hypertensive heart and renal disease
0.684 0.316 0.000
F45 Somatoform disorders
0.684 0.316 0.000
A65-A69 Other spirochaetal diseases
0.684 0.316 0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified
0.684 0.316 0.000
Y45.4 Antirheumatics
0.684 0.316 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.684 0.316 0.000
A39 Meningococcal infection
0.684 0.316 0.000
X45 Accidental poisoning by and exposure to alcohol
0.684 0.316 0.000
Y95 Nosocomial condition
0.682 0.318 0.000
S98 Traumatic amputation of ankle and foot
0.681 0.319 0.000
S97 Crushing injury of ankle and foot
0.681 0.319 0.000
S95 Injury of blood vessels at ankle and foot level
0.681 0.319 0.000
S94 Injury of nerves at ankle and foot level
0.681 0.319 0.000
I00-I02 Acute rheumatic fever
0.680 0.320 0.000
E23 Hypofunction and other disorders of pituitary gland
0.679 0.321 0.000
T25 Burn and corrosion of ankle and foot
0.678 0.322 0.000
S90.9 Superficial injury of ankle and foot, unspecified
0.678 0.322 0.000
T31 Burns classified according to extent of body surface involved
0.677 0.323 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.677 0.323 0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)
0.676 0.324 0.000
S32.2 Fracture of coccyx
0.676 0.324 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.676 0.324 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.676 0.324 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.674 0.325 0.000
B65-B83 Helminthiases
0.674 0.326 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.674 0.326 0.000
M90.7 Fracture of bone in neoplastic disease
0.674 0.326 0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent
0.673 0.327 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.673 0.327 0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)
0.672 0.327 0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis
0.672 0.328 0.000
S78 Traumatic amputation of hip and thigh
0.672 0.328 0.000
S77 Crushing injury of hip and thigh
0.672 0.328 0.000
S75 Injury of blood vessels at hip and thigh level
0.672 0.328 0.000
S74 Injury of nerves at hip and thigh level
0.672 0.328 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.672 0.328 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.672 0.328 0.000
Y40.8 Other systemic antibiotics
0.671 0.329 0.000
H61 Other disorders of external ear
0.671 0.329 0.000
S72.4 Fracture of lower end of femur
0.669 0.331 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.669 0.331 0.000
S82 Fracture of lower leg, including ankle
0.669 0.331 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.668 0.331 0.000
W07.0 Home
0.668 0.332 0.000
F60.9 Personality disorder, unspecified
0.668 0.332 0.000
M87.9 Osteonecrosis, unspecified
0.667 0.333 0.000
O29 Complications of anaesthesia during pregnancy
0.665 0.335 0.000
O28 Abnormal findings on antenatal screening of mother
0.665 0.335 0.000
O25 Malnutrition in pregnancy
0.665 0.335 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.665 0.335 0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.665 0.335 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.665 0.335 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.665 0.335 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.665 0.335 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.665 0.335 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.665 0.335 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.665 0.335 0.000
M46.8 Other specified inflammatory spondylopathies
0.664 0.335 0.000
M46.5 Other infective spondylopathies
0.664 0.335 0.000
M46.2 Osteomyelitis of vertebra
0.664 0.335 0.000
M46.1 Sacro-iliitis, not elsewhere classified
0.664 0.335 0.000
M46.0 Spinal enthesopathy
0.664 0.335 0.000
O26.9 Pregnancy-related condition, unspecified
0.664 0.336 0.000
S32.00 Fracture of lumbar vertebra (closed)
0.663 0.337 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.663 0.337 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.663 0.337 0.000
A75-A79 Rickettsioses
0.663 0.337 0.000
A70-A74 Other diseases caused by chlamydiae
0.663 0.337 0.000
A20-A28 Certain zoonotic bacterial diseases
0.663 0.337 0.000
M81.40 Drug-induced osteoporosis (Multiple sites)
0.663 0.337 0.000
A48 Other bacterial diseases, not elsewhere classified
0.662 0.338 0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
0.662 0.338 0.000
H80 Otosclerosis
0.662 0.338 0.000
H82 Vertiginous syndromes in diseases classified elsewhere
0.662 0.338 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.661 0.339 0.000
G25 Other extrapyramidal and movement disorders
0.661 0.339 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.661 0.339 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.660 0.339 0.000
Y40.9 Systemic antibiotic, unspecified
0.660 0.340 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.659 0.341 0.000
M62.8 Other specified disorders of muscle
0.659 0.341 0.000
Q50-Q56 Congenital malformations of genital organs
0.658 0.341 0.000
G23 Other degenerative diseases of basal ganglia
0.658 0.342 0.000
G21 Secondary Parkinsonism
0.658 0.342 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.658 0.342 0.000
G22 Parkinsonism in diseases classified elsewhere
0.658 0.342 0.000
H81.2 Vestibular neuronitis
0.658 0.342 0.000
F60.7 Dependent personality disorder
0.657 0.343 0.000
T11 Other injuries of upper limb, level unspecified
0.657 0.343 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.656 0.344 0.000
X47 Accidental poisoning by and exposure to other gases and vapours
0.656 0.344 0.000
M89.6 Osteopathy after poliomyelitis
0.655 0.345 0.000
M89.5 Osteolysis
0.655 0.345 0.000
M89.4 Other hypertrophic osteo-arthropathy
0.655 0.345 0.000
M89.3 Hypertrophy of bone
0.655 0.345 0.000
M89.2 Other disorders of bone development and growth
0.655 0.345 0.000
M89.1 Epiphyseal arrest
0.655 0.345 0.000
T43.2 Other and unspecified antidepressants
0.654 0.346 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.654 0.346 0.000
Q35-Q37 Cleft lip and cleft palate
0.654 0.346 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.654 0.346 0.000
Y54.3 Benzothiadiazine derivatives
0.653 0.347 0.000
M89.87 Other specified disorders of bone (Ankle and foot)
0.653 0.347 0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium
0.653 0.347 0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium
0.653 0.347 0.000
O26.5 Maternal hypotension syndrome
0.653 0.347 0.000
O26.4 Herpes gestationis
0.653 0.347 0.000
O26.3 Retained intra-uterine contraceptive device in pregnancy
0.653 0.347 0.000
O26.2 Pregnancy care of habitual aborter
0.653 0.347 0.000
O26.1 Low weight gain in pregnancy
0.653 0.347 0.000
O26.0 Excessive weight gain in pregnancy
0.653 0.347 0.000
W06 Fall involving bed
0.653 0.347 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.653 0.347 0.000
W15 Fall from cliff
0.653 0.347 0.000
W14 Fall from tree
0.653 0.347 0.000
W12 Fall on and from scaffolding
0.653 0.347 0.000
W11 Fall on and from ladder
0.653 0.347 0.000
W09 Fall involving playground equipment
0.653 0.347 0.000
W05 Fall involving wheelchair
0.653 0.347 0.000
W04 Fall while being carried or supported by other persons
0.653 0.347 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.653 0.347 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.653 0.347 0.000
W00 Fall on same level involving ice and snow
0.653 0.347 0.000
M89.81 Other specified disorders of bone (Shoulder region)
0.652 0.348 0.000
F99-F99 Unspecified mental disorder
0.651 0.349 0.000
S92.0 Fracture of calcaneus
0.651 0.349 0.000
W08 Fall involving other furniture
0.651 0.349 0.000
I05-I09 Chronic rheumatic heart diseases
0.651 0.349 0.000
X50-X57 Overexertion, travel and privation
0.650 0.350 0.000
E27.1 Primary adrenocortical insufficiency
0.650 0.350 0.000
S32.30 Fracture of ilium (closed)
0.649 0.351 0.000
T40.4 Other synthetic narcotics
0.649 0.351 0.000
O23.4 Unspecified infection of urinary tract in pregnancy
0.649 0.351 0.000
A49 Bacterial infection of unspecified site
0.646 0.354 0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system
0.646 0.354 0.000
H81.8 Other disorders of vestibular function
0.645 0.355 0.000
H81.4 Vertigo of central origin
0.645 0.355 0.000
H81.3 Other peripheral vertigo
0.645 0.355 0.000
S32.10 Fracture of sacrum (closed)
0.645 0.355 0.000
S32.70 Multiple fractures of lumbar spine and pelvis (closed)
0.644 0.356 0.000
M71 Other bursopathies
0.644 0.356 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.643 0.356 0.000
S92.4 Fracture of great toe
0.643 0.356 0.000
Y76 Obstetric and gynaecological devices associated with adverse incidents
0.642 0.358 0.000
G80 Infantile cerebral palsy
0.642 0.358 0.000
S90.0 Contusion of ankle
0.642 0.358 0.000
M67.9 Disorder of synovium and tendon, unspecified
0.641 0.359 0.000
M67.4 Ganglion
0.641 0.359 0.000
M67.3 Transient synovitis
0.641 0.359 0.000
M67.0 Short Achilles tendon (acquired)
0.641 0.359 0.000
H93.1 Tinnitus
0.640 0.360 0.000
T93.0 Sequelae of open wound of lower limb
0.640 0.360 0.000
T92.8 Sequelae of other specified injuries of upper limb
0.639 0.361 0.000
G82 Paraplegia and tetraplegia
0.639 0.361 0.000
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)
0.639 0.361 0.000
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)
0.639 0.361 0.000
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)
0.639 0.361 0.000
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)
0.639 0.361 0.000
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)
0.639 0.361 0.000
A44 Bartonellosis
0.639 0.361 0.000
A43 Nocardiosis
0.639 0.361 0.000
A42 Actinomycosis
0.639 0.361 0.000
A37 Whooping cough
0.639 0.361 0.000
A36 Diphtheria
0.639 0.361 0.000
A32 Listeriosis
0.639 0.361 0.000
A31 Infection due to other mycobacteria
0.639 0.361 0.000
A30 Leprosy [Hansen's disease]
0.639 0.361 0.000
A38 Scarlet fever
0.639 0.361 0.000
A35 Other tetanus
0.639 0.361 0.000
A34 Obstetrical tetanus
0.639 0.361 0.000
A33 Tetanus neonatorum
0.639 0.361 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.638 0.362 0.000
S30.1 Contusion of abdominal wall
0.638 0.362 0.000
I15 Secondary hypertension
0.637 0.363 0.000
A46 Erysipelas
0.636 0.364 0.000
H81.0 Meniere's disease
0.636 0.364 0.000
T43.9 Psychotropic drug, unspecified
0.636 0.364 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.636 0.364 0.000
T43.6 Psychostimulants with abuse potential
0.636 0.364 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.636 0.364 0.000
S88 Traumatic amputation of lower leg
0.636 0.364 0.000
S87 Crushing injury of lower leg
0.636 0.364 0.000
S85 Injury of blood vessels at lower leg level
0.636 0.364 0.000
S84 Injury of nerves at lower leg level
0.636 0.364 0.000
O24.9 Diabetes mellitus in pregnancy, unspecified
0.636 0.364 0.000
B99 Other and unspecified infectious diseases
0.635 0.365 0.000
F68 Other disorders of adult personality and behaviour
0.635 0.365 0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation
0.635 0.365 0.000
F65 Disorders of sexual preference
0.635 0.365 0.000
F64 Gender identity disorders
0.635 0.365 0.000
F63 Habit and impulse disorders
0.635 0.365 0.000
F62 Enduring personality changes, not attributable to brain damage and disease
0.635 0.365 0.000
F69 Unspecified disorder of adult personality and behaviour
0.635 0.365 0.000
F61 Mixed and other personality disorders
0.635 0.365 0.000
S39.7 Other multiple injuries of abdomen, lower back and pelvis
0.634 0.366 0.000
S39.6 Injury of intra-abdominal organ(s) with pelvic organ(s)
0.634 0.366 0.000
S39.0 Injury of muscle and tendon of abdomen, lower back and pelvis
0.634 0.366 0.000
Y40.7 Antifungal antibiotics, systemically used
0.634 0.366 0.000
Y40.6 Rifamycins
0.634 0.366 0.000
Y40.5 Aminoglycosides
0.634 0.366 0.000
Y40.4 Tetracyclines
0.634 0.366 0.000
Y40.2 Chloramphenicol group
0.634 0.366 0.000
T42.4 Benzodiazepines
0.634 0.366 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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