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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs75564153
log Bayes Factor = 12.9648
Chromosome 4   position 126,393,692  (GRCh37) Explore rs75564153 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
0.999 0.001 0.000
Chapter II Neoplasms
0.999 0.001 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.998 0.002 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.998 0.002 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.998 0.002 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.994 0.006 0.000
E10-E14 Diabetes mellitus
0.990 0.010 0.000
E14 Unspecified diabetes mellitus
0.988 0.012 0.000
E14.9 Without complications
0.986 0.014 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.978 0.022 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.971 0.029 0.000
S20-S29 Injuries to the thorax
0.971 0.029 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.967 0.033 0.000
S00-S09 Injuries to the head
0.967 0.033 0.000
E20-E35 Disorders of other endocrine glands
0.966 0.034 0.000
C50-C50 Malignant neoplasm of breast
0.964 0.036 0.000
O47 False labour
0.963 0.037 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.959 0.041 0.000
C64-C68 Malignant neoplasms of urinary tract
0.953 0.047 0.000
Chapter VII Diseases of the eye and adnexa
0.951 0.049 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.947 0.053 0.000
E70-E90 Metabolic disorders
0.946 0.054 0.000
C34 Malignant neoplasm of bronchus and lung
0.941 0.059 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.940 0.060 0.000
Y43 Primarily systemic agents
0.939 0.061 0.000
C50 Malignant neoplasm of breast
0.939 0.061 0.000
S01 Open wound of head
0.934 0.066 0.000
D00-D09 In situ neoplasms
0.933 0.067 0.000
T43.2 Other and unspecified antidepressants
0.932 0.068 0.000
E83 Disorders of mineral metabolism
0.929 0.071 0.000
Chapter VI Diseases of the nervous system
0.924 0.076 0.000
M80-M85 Disorders of bone density and structure
0.919 0.081 0.000
S01.8 Open wound of other parts of head
0.910 0.090 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.908 0.092 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.903 0.097 0.000
E83.5 Disorders of calcium metabolism
0.903 0.097 0.000
Chapter I Certain infectious and parasitic diseases
0.897 0.103 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.893 0.107 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.891 0.109 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.891 0.109 0.000
Y43.3 Other antineoplastic drugs
0.890 0.110 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.888 0.112 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.888 0.112 0.000
H53-H54 Visual disturbances and blindness
0.888 0.112 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.887 0.113 0.000
M70-M79 Other soft tissue disorders
0.885 0.115 0.000
Chapter V Mental and behavioural disorders
0.879 0.121 0.000
D04 Carcinoma in situ of skin
0.878 0.122 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.876 0.123 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.876 0.124 0.000
M81 Osteoporosis without pathological fracture
0.874 0.126 0.000
C50.2 Upper-inner quadrant of breast
0.874 0.126 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.872 0.128 0.000
C34.1 Upper lobe, bronchus or lung
0.872 0.128 0.000
O47.0 False labour before 37 completed weeks of gestation
0.869 0.131 0.000
C67 Malignant neoplasm of bladder
0.868 0.132 0.000
M45-M49 Spondylopathies
0.868 0.132 0.000
E83.1 Disorders of iron metabolism
0.866 0.134 0.000
G90-G99 Other disorders of the nervous system
0.865 0.135 0.000
H53 Visual disturbances
0.863 0.137 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.863 0.137 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.862 0.138 0.000
O43 Placental disorders
0.857 0.143 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.856 0.144 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.854 0.146 0.000
H30-H36 Disorders of choroid and retina
0.852 0.148 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.852 0.148 0.000
Chapter XXII Codes for special purposes
0.849 0.151 0.000
C34.3 Lower lobe, bronchus or lung
0.848 0.152 0.000
S27 Injury of other and unspecified intrathoracic organs
0.843 0.157 0.000
T90 Sequelae of injuries of head
0.842 0.158 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.841 0.159 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.839 0.161 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.839 0.161 0.000
C50.9 Breast, unspecified
0.839 0.161 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.838 0.162 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.837 0.163 0.000
Y40 Systemic antibiotics
0.837 0.163 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.836 0.164 0.000
E27 Other disorders of adrenal gland
0.836 0.164 0.000
H53.8 Other visual disturbances
0.836 0.164 0.000
O30 Multiple gestation
0.835 0.165 0.000
T43.6 Psychostimulants with abuse potential
0.835 0.165 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.834 0.166 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.834 0.166 0.000
S22.3 Fracture of rib
0.833 0.167 0.000
D04.3 Skin of other and unspecified parts of face
0.832 0.168 0.000
G40-G47 Episodic and paroxysmal disorders
0.823 0.177 0.000
S22.0 Fracture of thoracic vertebra
0.823 0.177 0.000
H40-H42 Glaucoma
0.821 0.179 0.000
M81.9 Osteoporosis, unspecified
0.820 0.180 0.000
X60-X84 Intentional self-harm
0.815 0.185 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.815 0.185 0.000
Y95 Nosocomial condition
0.814 0.186 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.813 0.187 0.000
M45 Ankylosing spondylitis
0.813 0.187 0.000
T81 Complications of procedures, not elsewhere classified
0.813 0.187 0.000
G30-G32 Other degenerative diseases of the nervous system
0.813 0.187 0.000
S00 Superficial injury of head
0.812 0.188 0.000
Chapter VIII Diseases of the ear and mastoid process
0.808 0.192 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.807 0.193 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.806 0.194 0.000
S01.7 Multiple open wounds of head
0.806 0.194 0.000
S22.2 Fracture of sternum
0.806 0.194 0.000
H55-H59 Other disorders of eye and adnexa
0.806 0.194 0.000
M79.1 Myalgia
0.800 0.199 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.799 0.201 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.798 0.202 0.000
M86-M90 Other osteopathies
0.797 0.203 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.796 0.204 0.000
G93 Other disorders of brain
0.796 0.204 0.000
O34.3 Maternal care for cervical incompetence
0.795 0.205 0.000
C50.3 Lower-inner quadrant of breast
0.795 0.205 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.792 0.208 0.000
T42.4 Benzodiazepines
0.791 0.209 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.791 0.209 0.000
T51 Toxic effect of alcohol
0.790 0.210 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.787 0.212 0.000
E13 Other specified diabetes mellitus
0.786 0.214 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.783 0.217 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.782 0.218 0.000
Y57 Other and unspecified drugs and medicaments
0.781 0.219 0.000
E16 Other disorders of pancreatic internal secretion
0.781 0.219 0.000
Y48 Anaesthetics and therapeutic gases
0.781 0.219 0.000
X50-X57 Overexertion, travel and privation
0.780 0.220 0.000
E23 Hypofunction and other disorders of pituitary gland
0.780 0.220 0.000
Y84.8 Other medical procedures
0.776 0.224 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.776 0.224 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.775 0.225 0.000
E86 Volume depletion
0.774 0.226 0.000
S40-S49 Injuries to the shoulder and upper arm
0.773 0.227 0.000
E34 Other endocrine disorders
0.771 0.229 0.000
D06 Carcinoma in situ of cervix uteri
0.770 0.230 0.000
T91 Sequelae of injuries of neck and trunk
0.770 0.230 0.000
S90-S99 Injuries to the ankle and foot
0.769 0.231 0.000
C51-C58 Malignant neoplasms of female genital organs
0.768 0.232 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.768 0.232 0.000
C65 Malignant neoplasm of renal pelvis
0.767 0.233 0.000
S02 Fracture of skull and facial bones
0.767 0.233 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.766 0.234 0.000
H34 Retinal vascular occlusions
0.766 0.234 0.000
F99-F99 Unspecified mental disorder
0.765 0.235 0.000
W50-W64 Exposure to animate mechanical forces
0.765 0.235 0.000
T92 Sequelae of injuries of upper limb
0.764 0.236 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.762 0.237 0.000
O42 Premature rupture of membranes
0.762 0.238 0.000
M79.8 Other specified soft tissue disorders
0.761 0.239 0.000
O40 Polyhydramnios
0.760 0.240 0.000
S01.9 Open wound of head, part unspecified
0.759 0.241 0.000
O34.7 Maternal care for abnormality of vulva and perineum
0.759 0.241 0.000
E21.0 Primary hyperparathyroidism
0.758 0.242 0.000
E26 Hyperaldosteronism
0.758 0.242 0.000
C50.0 Nipple and areola
0.758 0.242 0.000
O32.1 Maternal care for breech presentation
0.757 0.243 0.000
Y40.0 Penicillins
0.757 0.243 0.000
O43.8 Other placental disorders
0.757 0.243 0.000
H10-H13 Disorders of conjunctiva
0.756 0.244 0.000
S22.30 Fracture of rib (closed)
0.756 0.244 0.000
Chapter IX Diseases of the circulatory system
0.756 0.244 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.756 0.244 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.756 0.244 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.754 0.246 0.000
V40-V49 Car occupant injured in transport accident
0.754 0.246 0.000
I50.0 Congestive heart failure
0.754 0.246 0.000
S10-S19 Injuries to the neck
0.754 0.246 0.000
W00-W19 Falls
0.754 0.246 0.000
S05 Injury of eye and orbit
0.754 0.246 0.000
O34.8 Maternal care for other abnormalities of pelvic organs
0.753 0.247 0.000
I50 Heart failure
0.753 0.247 0.000
S01.4 Open wound of cheek and temporomandibular area
0.753 0.247 0.000
O85-O92 Complications predominantly related to the puerperium
0.752 0.248 0.000
I30-I52 Other forms of heart disease
0.751 0.249 0.000
M60-M63 Disorders of muscles
0.751 0.249 0.000
T86 Failure and rejection of transplanted organs and tissues
0.750 0.250 0.000
C80 Malignant neoplasm without specification of site
0.750 0.250 0.000
M72 Fibroblastic disorders
0.750 0.250 0.000
F00 Dementia in Alzheimer's disease
0.747 0.253 0.000
M91-M94 Chondropathies
0.746 0.254 0.000
B91 Sequelae of poliomyelitis
0.743 0.257 0.000
O48 Prolonged pregnancy
0.742 0.258 0.000
E00-E07 Disorders of thyroid gland
0.741 0.259 0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more
0.740 0.260 0.000
O41 Other disorders of amniotic fluid and membranes
0.740 0.260 0.000
C34.2 Middle lobe, bronchus or lung
0.740 0.260 0.000
B02 Zoster [herpes zoster]
0.740 0.260 0.000
G93.8 Other specified disorders of brain
0.740 0.260 0.000
S22.00 Fracture of thoracic vertebra (closed)
0.740 0.260 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.739 0.261 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.737 0.263 0.000
D03 Melanoma in situ
0.737 0.263 0.000
C67.4 Posterior wall of bladder
0.736 0.264 0.000
C32 Malignant neoplasm of larynx
0.735 0.265 0.000
H53.1 Subjective visual disturbances
0.733 0.267 0.000
G47 Sleep disorders
0.732 0.268 0.000
B00 Herpesviral [herpes simplex] infections
0.732 0.268 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.732 0.268 0.000
X20-X29 Contact with venomous animals and plants
0.732 0.268 0.000
T66-T78 Other and unspecified effects of external causes
0.731 0.269 0.000
E22 Hyperfunction of pituitary gland
0.730 0.270 0.000
D45 Polycythaemia vera
0.729 0.271 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.728 0.272 0.000
V80-V89 Other land transport accidents
0.728 0.272 0.000
B65-B83 Helminthiases
0.727 0.272 0.000
H40 Glaucoma
0.727 0.273 0.000
H53.0 Amblyopia ex anopsia
0.727 0.273 0.000
S01.3 Open wound of ear
0.725 0.275 0.000
A65-A69 Other spirochaetal diseases
0.725 0.275 0.000
T79-T79 Certain early complications of trauma
0.725 0.275 0.000
C66 Malignant neoplasm of ureter
0.724 0.275 0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.724 0.276 0.000
T93 Sequelae of injuries of lower limb
0.724 0.276 0.000
M81.4 Drug-induced osteoporosis
0.723 0.277 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.723 0.277 0.000
Y43.4 Immunosuppressive agents
0.722 0.278 0.000
C67.1 Dome of bladder
0.722 0.278 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.721 0.279 0.000
O44 Placenta praevia
0.721 0.279 0.000
T40.4 Other synthetic narcotics
0.720 0.280 0.000
O30.0 Twin pregnancy
0.719 0.281 0.000
T90.2 Sequelae of fracture of skull and facial bones
0.718 0.282 0.000
G95 Other diseases of spinal cord
0.718 0.282 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.718 0.282 0.000
M50-M54 Other dorsopathies
0.717 0.283 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.717 0.283 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.717 0.283 0.000
M79.10 Myalgia (Multiple sites)
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.717 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.717 0.283 0.000
Y10-Y34 Event of undetermined intent
0.717 0.283 0.000
Y00-Y09 Assault
0.717 0.283 0.000
X85-X99 Assault
0.717 0.283 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.717 0.283 0.000
X30-X39 Exposure to forces of nature
0.717 0.283 0.000
X10-X19 Contact with heat and hot substances
0.717 0.283 0.000
X00-X09 Exposure to smoke, fire and flames
0.717 0.283 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.717 0.283 0.000
W75-W84 Other accidental threats to breathing
0.717 0.283 0.000
W65-W74 Accidental drowning and submersion
0.717 0.283 0.000
V98-V99 Other and unspecified transport accidents
0.717 0.283 0.000
V95-V97 Air and space transport accidents
0.717 0.283 0.000
V90-V94 Water transport accidents
0.717 0.283 0.000
V70-V79 Bus occupant injured in transport accident
0.717 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.717 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.717 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.717 0.283 0.000
V01-V09 Pedestrian injured in transport accident
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.716 0.284 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.284 0.000
E16.2 Hypoglycaemia, unspecified
0.716 0.284 0.000
I49 Other cardiac arrhythmias
0.716 0.284 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.716 0.284 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.716 0.284 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.716 0.284 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.716 0.284 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.716 0.284 0.000
T36 Poisoning by systemic antibiotics
0.716 0.284 0.000
O45 Premature separation of placenta [abruptio placentae]
0.715 0.285 0.000
O33 Maternal care for known or suspected disproportion
0.715 0.285 0.000
O31 Complications specific to multiple gestation
0.715 0.285 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.714 0.286 0.000
Y84.2 Radiological procedure and radiotherapy
0.713 0.287 0.000
G30 Alzheimer's disease
0.713 0.287 0.000
Y59 Other and unspecified vaccines and biological substances
0.713 0.287 0.000
Y58 Bacterial vaccines
0.713 0.287 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.713 0.287 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.713 0.287 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.713 0.287 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.713 0.287 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.713 0.287 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.713 0.287 0.000
T90.4 Sequelae of injury of eye and orbit
0.712 0.288 0.000
E14.3 With ophthalmic complications
0.712 0.288 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.711 0.289 0.000
O35.8 Maternal care for other (suspected) foetal abnormality and damage
0.710 0.290 0.000
D46 Myelodysplastic syndromes
0.710 0.290 0.000
E12 Malnutrition-related diabetes mellitus
0.710 0.290 0.000
S22.20 Fracture of sternum (closed)
0.710 0.290 0.000
C34.9 Bronchus or lung, unspecified
0.709 0.291 0.000
G43 Migraine
0.709 0.291 0.000
E14.8 With unspecified complications
0.708 0.292 0.000
E14.7 With multiple complications
0.708 0.292 0.000
E14.6 With other specified complications
0.708 0.292 0.000
E14.5 With peripheral circulatory complications
0.708 0.292 0.000
E14.4 With neurological complications
0.708 0.292 0.000
E14.2 Withrenal complications
0.708 0.292 0.000
E14.1 With ketoacidosis
0.708 0.292 0.000
E14.0 With coma
0.708 0.292 0.000
E85 Amyloidosis
0.708 0.292 0.000
I50.9 Heart failure, unspecified
0.706 0.294 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.706 0.294 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.705 0.295 0.000
C67.2 Lateral wall of bladder
0.705 0.295 0.000
O20 Haemorrhage in early pregnancy
0.704 0.296 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.704 0.296 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.702 0.298 0.000
I47 Paroxysmal tachycardia
0.702 0.298 0.000
I05-I09 Chronic rheumatic heart diseases
0.702 0.298 0.000
Y84.0 Cardiac catheterisation
0.702 0.298 0.000
T43.9 Psychotropic drug, unspecified
0.701 0.299 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.701 0.299 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.701 0.299 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.701 0.299 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.701 0.299 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.698 0.301 0.000
M81.98 Osteoporosis, unspecified (Other)
0.698 0.302 0.000
H40.1 Primary open-angle glaucoma
0.698 0.302 0.000
S27.3 Other injuries of lung
0.697 0.303 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.697 0.303 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.696 0.304 0.000
S26 Injury of heart
0.696 0.304 0.000
S25 Injury of blood vessels of thorax
0.696 0.304 0.000
S24 Injury of nerves and spinal cord at thorax level
0.696 0.304 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.696 0.304 0.000
S21 Open wound of thorax
0.696 0.304 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.695 0.305 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.693 0.306 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.693 0.306 0.000
C31 Malignant neoplasm of accessory sinuses
0.693 0.306 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.693 0.306 0.000
C37 Malignant neoplasm of thymus
0.693 0.306 0.000
C33 Malignant neoplasm of trachea
0.693 0.306 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.693 0.306 0.000
S08 Traumatic amputation of part of head
0.693 0.307 0.000
S07 Crushing injury of head
0.693 0.307 0.000
S04 Injury of cranial nerves
0.693 0.307 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.693 0.307 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.693 0.307 0.000
E32 Diseases of thymus
0.693 0.307 0.000
E31 Polyglandular dysfunction
0.693 0.307 0.000
E30 Disorders of puberty, not elsewhere classified
0.693 0.307 0.000
E25 Adrenogenital disorders
0.693 0.307 0.000
E24 Cushing's syndrome
0.693 0.307 0.000
E20 Hypoparathyroidism
0.693 0.307 0.000
T39.0 Salicylates
0.693 0.307 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.692 0.308 0.000
H34.8 Other retinal vascular occlusions
0.692 0.308 0.000
S22.4 Multiple fractures of ribs
0.691 0.309 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.691 0.309 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.690 0.310 0.000
T58 Toxic effect of carbon monoxide
0.690 0.310 0.000
V20-V29 Motorcycle rider injured in transport accident
0.689 0.311 0.000
E21.3 Hyperparathyroidism, unspecified
0.689 0.311 0.000
M79.19 Myalgia (Site unspecified)
0.688 0.312 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.688 0.312 0.000
M85 Other disorders of bone density and structure
0.688 0.312 0.000
T51.0 Ethanol
0.688 0.312 0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified
0.688 0.312 0.000
O34.6 Maternal care for abnormality of vagina
0.688 0.312 0.000
O34.5 Maternal care for other abnormalities of gravid uterus
0.688 0.312 0.000
O34.4 Maternal care for other abnormalities of cervix
0.688 0.312 0.000
O34.0 Maternal care for congenital malformation of uterus
0.688 0.312 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.687 0.313 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.686 0.314 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.686 0.314 0.000
I49.3 Ventricular premature depolarisation
0.686 0.314 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.684 0.316 0.000
S29 Other and unspecified injuries of thorax
0.684 0.316 0.000
F99 Mental disorder, not otherwise specified
0.683 0.316 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.683 0.317 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.683 0.317 0.000
G47.9 Sleep disorder, unspecified
0.682 0.318 0.000
C67.3 Anterior wall of bladder
0.681 0.319 0.000
H33 Retinal detachments and breaks
0.681 0.319 0.000
I08 Multiple valve diseases
0.681 0.319 0.000
Q00-Q07 Congenital malformations of the nervous system
0.681 0.319 0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system
0.679 0.321 0.000
Y43.1 Antineoplastic antimetabolites
0.679 0.321 0.000
M84 Disorders of continuity of bone
0.679 0.321 0.000
T98 Sequelae of other and unspecified effects of external causes
0.679 0.321 0.000
T95 Sequelae of burns, corrosions and frostbite
0.679 0.321 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.679 0.321 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.679 0.321 0.000
M89 Other disorders of bone
0.679 0.321 0.000
Y44 Agents primarily affecting blood constituents
0.679 0.321 0.000
E84 Cystic fibrosis
0.678 0.322 0.000
E79 Disorders of purine and pyrimidine metabolism
0.678 0.322 0.000
E77 Disorders of glycoprotein metabolism
0.678 0.322 0.000
E76 Disorders of glycosaminoglycan metabolism
0.678 0.322 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.678 0.322 0.000
E74 Other disorders of carbohydrate metabolism
0.678 0.322 0.000
E73 Lactose intolerance
0.678 0.322 0.000
E72 Other disorders of amino-acid metabolism
0.678 0.322 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.678 0.322 0.000
E70 Disorders of aromatic amino-acid metabolism
0.678 0.322 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.678 0.322 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.678 0.322 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.677 0.323 0.000
M00-M03 Infectious arthropathies
0.676 0.323 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.676 0.324 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.675 0.325 0.000
C34.8 Overlapping lesion of bronchus and lung
0.674 0.325 0.000
S22.9 Fracture of bony thorax, part unspecified
0.674 0.326 0.000
S22.8 Fracture of other parts of bony thorax
0.674 0.326 0.000
S22.5 Flail chest
0.674 0.326 0.000
S22.1 Multiple fractures of thoracic spine
0.674 0.326 0.000
Y42.7 Androgens and anabolic congeners
0.674 0.326 0.000
Y43.9 Primarily systemic agent, unspecified
0.673 0.326 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.673 0.326 0.000
Y43.6 Enzymes, not elsewhere classified
0.673 0.326 0.000
Y43.5 Acidifying and alkalising agents
0.673 0.326 0.000
Y43.2 Antineoplastic natural products
0.673 0.326 0.000
Y43.0 Antiallergic and antiemetic drugs
0.673 0.326 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.673 0.327 0.000
C50.6 Axillary tail of breast
0.673 0.327 0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours
0.672 0.328 0.000
C78.2 Secondary malignant neoplasm of pleura
0.671 0.329 0.000
W18 Other fall on same level
0.671 0.329 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.669 0.330 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.669 0.331 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.669 0.331 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.669 0.331 0.000
E40-E46 Malnutrition
0.669 0.331 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.668 0.332 0.000
F00.9 Dementia in Alzheimer's disease, unspecified
0.667 0.333 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.667 0.333 0.000
B15-B19 Viral hepatitis
0.667 0.333 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.666 0.334 0.000
E83.8 Other disorders of mineral metabolism
0.666 0.334 0.000
E83.2 Disorders of zinc metabolism
0.666 0.334 0.000
E83.0 Disorders of copper metabolism
0.666 0.334 0.000
M82 Osteoporosis in diseases classified elsewhere
0.666 0.334 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.666 0.334 0.000
I47.1 Supraventricular tachycardia
0.666 0.334 0.000
E27.2 Addisonian crisis
0.665 0.335 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.664 0.336 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.664 0.336 0.000
G96 Other disorders of central nervous system
0.664 0.336 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.663 0.337 0.000
H65-H75 Diseases of middle ear and mastoid
0.662 0.338 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.660 0.340 0.000
M40-M43 Deforming dorsopathies
0.660 0.340 0.000
E23.2 Diabetes insipidus
0.659 0.341 0.000
M83 Adult osteomalacia
0.659 0.341 0.000
E88 Other metabolic disorders
0.659 0.341 0.000
C50.8 Overlapping lesion of breast
0.659 0.341 0.000
D09 Carcinoma in situ of other and unspecified sites
0.658 0.342 0.000
M79.83 Other specified soft tissue disorders (Forearm)
0.658 0.342 0.000
V10-V19 Pedal cyclist injured in transport accident
0.658 0.342 0.000
C50.1 Central portion of breast
0.658 0.342 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.657 0.343 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.657 0.343 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.657 0.343 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.656 0.343 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.656 0.344 0.000
S27.2 Traumatic heamopneumothorax
0.654 0.346 0.000
Q50-Q56 Congenital malformations of genital organs
0.654 0.346 0.000
D06.9 Cervix, unspecified
0.654 0.346 0.000
T18 Foreign body in alimentary tract
0.653 0.346 0.000
M80 Osteoporosis with pathological fracture
0.653 0.347 0.000
H35 Other retinal disorders
0.653 0.347 0.000
D04.6 Skin of upper limb, including shoulder
0.653 0.347 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.653 0.347 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.652 0.348 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.651 0.349 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.651 0.349 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.651 0.349 0.000
T42.3 Barbiturates
0.651 0.349 0.000
T42.2 Succinimides and oxazolidinediones
0.651 0.349 0.000
T42.1 Iminostilbenes
0.651 0.349 0.000
T42.0 Hydantoin derivatives
0.651 0.349 0.000
S06 Intracranial injury
0.651 0.349 0.000
O32.8 Maternal care for other malpresentation of foetus
0.650 0.350 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.650 0.350 0.000
H57 Other disorders of eye and adnexa
0.649 0.351 0.000
T21 Burn and corrosion of trunk
0.649 0.351 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.647 0.353 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.647 0.353 0.000
Y45.1 Salicylates
0.647 0.353 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.646 0.354 0.000
D04.7 Skin of lower limb, including hip
0.646 0.354 0.000
M49 Spondylopathies in diseases classified elsewhere
0.646 0.354 0.000
T23 Burn and corrosion of wrist and hand
0.644 0.356 0.000
C67.5 Bladder neck
0.644 0.356 0.000
O34.1 Maternal care for tumour of corpus uteri
0.643 0.356 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.643 0.357 0.000
B50-B64 Protozoal diseases
0.643 0.357 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.643 0.357 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.643 0.357 0.000
A75-A79 Rickettsioses
0.643 0.357 0.000
A70-A74 Other diseases caused by chlamydiae
0.643 0.357 0.000
A20-A28 Certain zoonotic bacterial diseases
0.643 0.357 0.000
A15-A19 Tuberculosis
0.643 0.357 0.000
M79.16 Myalgia (Lower leg)
0.643 0.357 0.000
H31 Other disorders of choroid
0.642 0.358 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.642 0.358 0.000
S01.2 Open wound of nose
0.641 0.359 0.000
E13.9 Without complications
0.639 0.361 0.000
O47.9 False labour, unspecified
0.639 0.361 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.639 0.361 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.639 0.361 0.000
Y98 Lifestyle-related condition
0.639 0.361 0.000
Y97 Environmental-pollution-related condition
0.639 0.361 0.000
Y96 Work-related condition
0.639 0.361 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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