TreeWAS – Variant ID: rs1799964

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K90.0 Coeliac disease	0.000	0.000	1.000
L40.9 Psoriasis, unspecified	1.000	0.000	0.000
E11 Non-insulin-dependent diabetes mellitus	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
L40 Psoriasis	1.000	0.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
Chapter V Mental and behavioural disorders	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
E78.0 Pure hypercholesterolaemia	1.000	0.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000	0.000
E11.9 Without complications	1.000	0.000	0.000
L40-L45 Papulosquamous disorders	1.000	0.000	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	1.000	0.000	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	1.000	0.000	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	1.000	0.000	0.000
H65-H75 Diseases of middle ear and mastoid	1.000	0.000	0.000
Chapter VIII Diseases of the ear and mastoid process	1.000	0.000	0.000
E70-E90 Metabolic disorders	1.000	0.000	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.999	0.001	0.000
E10.9 Without complications	0.999	0.001	0.000
F30-F39 Mood [affective] disorders	0.999	0.001	0.000
H71 Cholesteatoma of middle ear	0.999	0.001	0.000
E11.3 With ophthalmic complications	0.998	0.002	0.000
F41 Other anxiety disorders	0.998	0.002	0.000
L40.5 Arthropathic psoriasis	0.998	0.002	0.000
L00-L08 Infections of the skin and subcutaneous tissue	0.997	0.003	0.000
E10.3 With ophthalmic complications	0.993	0.007	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.987	0.013	0.000
F30 Manic episode	0.986	0.014	0.000
F60-F69 Disorders of adult personality and behaviour	0.984	0.016	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.982	0.018	0.000
I10 Essential (primary) hypertension	0.981	0.019	0.000
T85 Complications of other internal prosthetic devices, implants and grafts	0.980	0.020	0.000
F33 Recurrent depressive disorder	0.980	0.020	0.000
L05 Pilonidal cyst	0.978	0.022	0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.977	0.023	0.000
F41.2 Mixed anxiety and depressive disorder	0.977	0.023	0.000
E10.4 With neurological complications	0.973	0.027	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.972	0.028	0.000
F60 Specific personality disorders	0.971	0.029	0.000
T88.7 Unspecified adverse effect of drug or medicament	0.965	0.035	0.000
Chapter XX External causes of morbidity and mortality	0.963	0.037	0.000
L03 Cellulitis	0.961	0.039	0.000
F30.0 Hypomania	0.958	0.042	0.000
L03.3 Cellulitis of trunk	0.958	0.042	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.958	0.042	0.000
F41.9 Anxiety disorder, unspecified	0.956	0.044	0.000
L05.0 Pilonidal cyst with abscess	0.955	0.045	0.000
E20-E35 Disorders of other endocrine glands	0.955	0.045	0.000
F33.9 Recurrent depressive disorder, unspecified	0.948	0.052	0.000
I10-I15 Hypertensive diseases	0.945	0.055	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.944	0.056	0.000
E10.1 With ketoacidosis	0.943	0.057	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.943	0.057	0.000
Chapter IX Diseases of the circulatory system	0.941	0.059	0.000
E10.5 With peripheral circulatory complications	0.939	0.061	0.000
F60.9 Personality disorder, unspecified	0.938	0.062	0.000
K50 Crohn's disease [regional enteritis]	0.934	0.066	0.000
K50.9 Crohn's disease, unspecified	0.934	0.066	0.000
F41.1 Generalised anxiety disorder	0.934	0.066	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.931	0.069	0.000
H66 Suppurative and unspecified otitis media	0.930	0.070	0.000
E21.3 Hyperparathyroidism, unspecified	0.929	0.071	0.000
H72 Perforation of tympanic membrane	0.929	0.071	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.917	0.083	0.000
H73 Other disorders of tympanic membrane	0.913	0.087	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.910	0.090	0.000
S32 Fracture of lumbar spine and pelvis	0.905	0.095	0.000
H66.3 Other chronic suppurative otitis media	0.905	0.095	0.000
F45 Somatoform disorders	0.904	0.096	0.000
E11.4 With neurological complications	0.904	0.096	0.000
F43 Reaction to severe stress, and adjustment disorders	0.903	0.097	0.000
L40.0 Psoriasis vulgaris	0.903	0.097	0.000
F60.3 Emotionally unstable personality disorder	0.901	0.099	0.000
K50-K52 Noninfective enteritis and colitis	0.900	0.100	0.000
E14 Unspecified diabetes mellitus	0.899	0.101	0.000
S40-S49 Injuries to the shoulder and upper arm	0.898	0.102	0.000
T36 Poisoning by systemic antibiotics	0.897	0.103	0.000
T42.4 Benzodiazepines	0.896	0.104	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.894	0.106	0.000
Chapter XI Diseases of the digestive system	0.891	0.109	0.000
E85 Amyloidosis	0.888	0.111	0.000
H90-H95 Other disorders of ear	0.888	0.112	0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.888	0.112	0.000
K90-K93 Other diseases of the digestive system	0.882	0.113	0.004
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.885	0.115	0.000
F32 Depressive episode	0.884	0.116	0.000
F30.9 Manic episode, unspecified	0.883	0.117	0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.882	0.118	0.000
Y57 Other and unspecified drugs and medicaments	0.882	0.118	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.881	0.119	0.000
F01 Vascular dementia	0.879	0.121	0.000
W00-W19 Falls	0.873	0.127	0.000
H72.0 Central perforation of tympanic membrane	0.872	0.128	0.000
T66-T78 Other and unspecified effects of external causes	0.872	0.128	0.000
T50.8 Diagnostic agents	0.872	0.128	0.000
F44 Dissociative [conversion] disorders	0.871	0.129	0.000
V10-V19 Pedal cyclist injured in transport accident	0.871	0.129	0.000
K50.0 Crohn's disease of small intestine	0.871	0.129	0.000
E10.8 With unspecified complications	0.869	0.131	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.867	0.133	0.000
S32.4 Fracture of acetabulum	0.866	0.134	0.000
L02 Cutaneous abscess, furuncle and carbuncle	0.865	0.135	0.000
W50-W64 Exposure to animate mechanical forces	0.865	0.135	0.000
F43.0 Acute stress reaction	0.863	0.137	0.000
K50.8 Other Crohn's disease	0.862	0.138	0.000
F80-F89 Disorders of psychological development	0.861	0.139	0.000
S90-S99 Injuries to the ankle and foot	0.860	0.140	0.000
E50-E64 Other nutritional deficiencies	0.858	0.142	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.856	0.144	0.000
H73.8 Other specified disorders of tympanic membrane	0.852	0.148	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.852	0.148	0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.852	0.148	0.000
E88 Other metabolic disorders	0.851	0.149	0.000
E11.6 With other specified complications	0.849	0.151	0.000
F45.8 Other somatoform disorders	0.849	0.151	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.847	0.153	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.847	0.153	0.000
S32.40 Fracture of acetabulum (closed)	0.839	0.161	0.000
F32.2 Severe depressive episode without psychotic symptoms	0.837	0.163	0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.834	0.166	0.000
E11.2 With renal complications	0.834	0.166	0.000
F01.9 Vascular dementia, unspecified	0.834	0.166	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.833	0.167	0.000
Y40 Systemic antibiotics	0.833	0.167	0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.832	0.168	0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.831	0.169	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.827	0.173	0.000
K91.0 Vomiting following gastro-intestinal surgery	0.826	0.174	0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.825	0.175	0.000
T36.0 Penicillins	0.823	0.177	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.823	0.177	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.823	0.177	0.000
E89.1 Postprocedural hypoinsulinaemia	0.819	0.181	0.000
H92 Otalgia and effusion of ear	0.819	0.181	0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.816	0.184	0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck	0.816	0.184	0.000
L05.9 Pilonidal cyst without abscess	0.816	0.184	0.000
W20-W49 Exposure to inanimate mechanical forces	0.815	0.185	0.000
F17 Mental and behavioural disorders due to use of tobacco	0.813	0.187	0.000
Y57.9 Drug or medicament, unspecified	0.812	0.188	0.000
L43 Lichen planus	0.810	0.190	0.000
F17.1 Harmful use	0.810	0.190	0.000
Y10-Y34 Event of undetermined intent	0.808	0.192	0.000
I05-I09 Chronic rheumatic heart diseases	0.808	0.192	0.000
Y59 Other and unspecified vaccines and biological substances	0.807	0.193	0.000
E61 Deficiency of other nutrient elements	0.806	0.194	0.000
E11.0 With coma	0.805	0.194	0.000
F33.0 Recurrent depressive disorder, current episode mild	0.805	0.195	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.804	0.195	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.803	0.197	0.000
F32.9 Depressive episode, unspecified	0.802	0.198	0.000
L40.8 Other psoriasis	0.801	0.199	0.000
T78 Adverse effects, not elsewhere classified	0.801	0.199	0.000
H93 Other disorders of ear, not elsewhere classified	0.800	0.200	0.000
L04 Acute lymphadenitis	0.798	0.202	0.000
T42.1 Iminostilbenes	0.798	0.202	0.000
L42 Pityriasis rosea	0.796	0.204	0.000
E89.3 Postprocedural hypopituitarism	0.793	0.207	0.000
E65-E68 Obesity and other hyperalimentation	0.790	0.210	0.000
F60.5 Anankastic personality disorder	0.788	0.212	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.786	0.214	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.785	0.215	0.000
Y57.8 Other drugs and medicaments	0.784	0.216	0.000
K50.1 Crohn's disease of large intestine	0.783	0.217	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.783	0.217	0.000
X50-X57 Overexertion, travel and privation	0.779	0.221	0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb	0.778	0.222	0.000
V18 Pedal cyclist injured in noncollision transport accident	0.777	0.223	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.776	0.224	0.000
E61.1 Iron deficiency	0.775	0.225	0.000
F84 Pervasive developmental disorders	0.774	0.226	0.000
E20 Hypoparathyroidism	0.771	0.229	0.000
I20-I25 Ischaemic heart diseases	0.771	0.229	0.000
S42 Fracture of shoulder and upper arm	0.771	0.229	0.000
E79 Disorders of purine and pyrimidine metabolism	0.771	0.229	0.000
E10.6 With other specified complications	0.769	0.231	0.000
Y00-Y09 Assault	0.768	0.232	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.767	0.233	0.000
T00-T07 Injuries involving multiple body regions	0.766	0.233	0.000
E78.6 Lipoprotein deficiency	0.766	0.234	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.766	0.234	0.000
F41.3 Other mixed anxiety disorders	0.766	0.234	0.000
T88.4 Failed or difficult intubation	0.765	0.235	0.000
E10.0 With coma	0.764	0.236	0.000
E26 Hyperaldosteronism	0.762	0.238	0.000
S40 Superficial injury of shoulder and upper arm	0.761	0.239	0.000
L40.1 Generalised pustular psoriasis	0.759	0.240	0.000
V70-V79 Bus occupant injured in transport accident	0.758	0.242	0.000
H93.9 Disorder of ear, unspecified	0.758	0.242	0.000
K90 Intestinal malabsorption	0.118	0.242	0.641
H92.1 Otorrhoea	0.757	0.243	0.000
E85.9 Amyloidosis, unspecified	0.757	0.243	0.000
T88.9 Complication of surgical and medical care, unspecified	0.756	0.244	0.000
F34 Persistent mood [affective] disorders	0.756	0.244	0.000
E28 Ovarian dysfunction	0.755	0.245	0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.754	0.246	0.000
S43.0 Dislocation of shoulder joint	0.754	0.246	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.751	0.249	0.000
T88.2 Shock due to anaesthesia	0.751	0.249	0.000
S37 Injury of urinary and pelvic organs	0.751	0.249	0.000
T11 Other injuries of upper limb, level unspecified	0.750	0.250	0.000
T50.4 Drugs affecting uric acid metabolism	0.749	0.251	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.748	0.252	0.000
W15 Fall from cliff	0.747	0.253	0.000
H72.8 Other perforations of tympanic membrane	0.746	0.254	0.000
E21.2 Other hyperparathyroidism	0.746	0.254	0.000
H66.4 Suppurative otitis media, unspecified	0.745	0.255	0.000
W17 Other fall from one level to another	0.745	0.255	0.000
W75-W84 Other accidental threats to breathing	0.744	0.256	0.000
E11.1 With ketoacidosis	0.744	0.256	0.000
Y40.0 Penicillins	0.744	0.256	0.000
E14.8 With unspecified complications	0.743	0.257	0.000
F06.7 Mild cognitive disorder	0.742	0.258	0.000
S39.8 Other specified injuries of abdomen, lower back and pelvis	0.741	0.259	0.000
V98-V99 Other and unspecified transport accidents	0.741	0.259	0.000
E21.4 Other specified disorders of parathyroid gland	0.741	0.259	0.000
E14.4 With neurological complications	0.740	0.260	0.000
L40.3 Pustulosis palmaris et plantaris	0.740	0.260	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.739	0.261	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.736	0.263	0.000
W08 Fall involving other furniture	0.735	0.265	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.734	0.266	0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.734	0.266	0.000
F69 Unspecified disorder of adult personality and behaviour	0.734	0.266	0.000
E65 Localised adiposity	0.733	0.267	0.000
Y59.3 Immunoglobulin	0.733	0.267	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.732	0.268	0.000
L43.8 Other lichen planus	0.732	0.268	0.000
E74 Other disorders of carbohydrate metabolism	0.732	0.268	0.000
V90-V94 Water transport accidents	0.732	0.268	0.000
F30.2 Mania with psychotic symptoms	0.730	0.269	0.000
F39 Unspecified mood [affective] disorder	0.730	0.270	0.000
S42.1 Fracture of scapula	0.729	0.271	0.000
S97 Crushing injury of ankle and foot	0.729	0.271	0.000
T87 Complications peculiar to reattachment and amputation	0.729	0.271	0.000
E89.2 Postprocedural hypoparathyroidism	0.728	0.272	0.000
F62 Enduring personality changes, not attributable to brain damage and disease	0.728	0.272	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.728	0.272	0.000
F99-F99 Unspecified mental disorder	0.727	0.273	0.000
Q80-Q89 Other congenital malformations	0.727	0.273	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.727	0.273	0.000
V01-V09 Pedestrian injured in transport accident	0.726	0.274	0.000
Y57.6 Other diagnostic agents	0.725	0.275	0.000
W55 Bitten or struck by other mammals	0.724	0.276	0.000
T78.3 Angioneurotic oedema	0.724	0.276	0.000
W03 Other fall on same level due to collision with, or pushing by, another person	0.723	0.277	0.000
K91.9 Postprocedural disorder of digestive system, unspecified	0.723	0.277	0.000
X00-X09 Exposure to smoke, fire and flames	0.723	0.277	0.000
Q21 Congenital malformations of cardiac septa	0.722	0.278	0.000
V95-V97 Air and space transport accidents	0.722	0.278	0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.721	0.279	0.000
Y52 Agents primarily affecting the cardiovascular system	0.719	0.281	0.000
S32.1 Fracture of sacrum	0.719	0.281	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.719	0.281	0.000
I24 Other acute ischaemic heart diseases	0.718	0.282	0.000
L03.8 Cellulitis of other sites	0.718	0.282	0.000
E10.7 With multiple complications	0.717	0.283	0.000
E11.7 With multiple complications	0.717	0.283	0.000
L40.4 Guttate psoriasis	0.717	0.283	0.000
L40.2 Acrodermatitis continua	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
W60 Contact with plant thorns and spines and sharp leaves	0.717	0.283	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
T33-T35 Frostbite	0.717	0.283	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.717	0.283	0.000
L44 Other papulosquamous disorders	0.717	0.283	0.000
L41 Parapsoriasis	0.717	0.283	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.717	0.283	0.000
H72.2 Other marginal perforations of tympanic membrane	0.717	0.283	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.717	0.283	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.717	0.283	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.717	0.283	0.000
H68 Eustachian salpingitis and obstruction	0.717	0.283	0.000
H67 Otitis media in diseases classified elsewhere	0.717	0.283	0.000
E77 Disorders of glycoprotein metabolism	0.717	0.283	0.000
E76 Disorders of glycosaminoglycan metabolism	0.717	0.283	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.717	0.283	0.000
E72 Other disorders of amino-acid metabolism	0.717	0.283	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.717	0.283	0.000
E70 Disorders of aromatic amino-acid metabolism	0.717	0.283	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.717	0.283	0.000
E78.3 Hyperchylomicronaemia	0.716	0.284	0.000
F38 Other mood [affective] disorders	0.716	0.284	0.000
F41.8 Other specified anxiety disorders	0.716	0.284	0.000
F44.9 Dissociative [conversion] disorder, unspecified	0.716	0.284	0.000
I20 Angina pectoris	0.716	0.284	0.000
T78.1 Other adverse food reactions, not elsewhere classified	0.715	0.285	0.000
E84 Cystic fibrosis	0.715	0.285	0.000
L01 Impetigo	0.715	0.285	0.000
L00 Staphylococcal scalded skin syndrome	0.715	0.285	0.000
E11.5 With peripheral circulatory complications	0.714	0.286	0.000
I05 Rheumatic mitral valve diseases	0.714	0.286	0.000
F02 Dementia in other diseases classified elsewhere	0.712	0.288	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.710	0.290	0.000
K52 Other non-infective gastro-enteritis and colitis	0.710	0.290	0.000
E25 Adrenogenital disorders	0.710	0.290	0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.709	0.291	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.708	0.292	0.000
F30.8 Other manic episodes	0.707	0.293	0.000
F30.1 Mania without psychotic symptoms	0.707	0.293	0.000
E89.4 Postprocedural ovarian failure	0.707	0.293	0.000
S92 Fracture of foot, except ankle	0.707	0.293	0.000
W50 Hit, struck, kicked, twisted, bitten or scratched by another person	0.707	0.293	0.000
T70 Effects of air pressure and water pressure	0.706	0.293	0.000
I20.0 Unstable angina	0.707	0.293	0.000
Q25 Congenital malformations of great arteries	0.706	0.294	0.000
F68 Other disorders of adult personality and behaviour	0.705	0.295	0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation	0.705	0.295	0.000
F65 Disorders of sexual preference	0.705	0.295	0.000
F63 Habit and impulse disorders	0.705	0.295	0.000
F61 Mixed and other personality disorders	0.705	0.295	0.000
T88.3 Malignant hyperthermia due to anaesthesis	0.704	0.296	0.000
T88.1 Other complications following immunisation, not elsewhere classified	0.704	0.296	0.000
T88.0 Infection following immunisation	0.704	0.296	0.000
S31 Open wound of abdomen, lower back and pelvis	0.704	0.296	0.000
T42.0 Hydantoin derivatives	0.704	0.296	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.703	0.296	0.000
E51 Thiamine deficiency	0.703	0.297	0.000
E85.3 Secondary systemic amyloidosis	0.703	0.297	0.000
F43.2 Adjustment disorders	0.703	0.297	0.000
F84.5 Asperger's syndrome	0.703	0.297	0.000
F33.8 Other recurrent depressive disorders	0.702	0.297	0.000
F33.4 Recurrent depressive disorder, currently in remission	0.702	0.297	0.000
S42.10 Fracture of scapula (closed)	0.700	0.300	0.000
V14 Pedal cyclist injured in collision with heavy transport vehicle or bus	0.699	0.301	0.000
F44.0 Dissociative amnesia	0.698	0.302	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.698	0.302	0.000
Y28 Contact with sharp object, undetermined intent	0.697	0.303	0.000
T50.7 Analeptics and opioid receptor antagonists	0.697	0.303	0.000
T50.5 Appetite depressants	0.697	0.303	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.697	0.303	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.697	0.303	0.000
T50.1 Loop [high-ceiling] diuretics	0.697	0.303	0.000
T50.0 Mineralocorticoids and their antagonists	0.697	0.303	0.000
S32.3 Fracture of ilium	0.697	0.303	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.697	0.303	0.000
F60.8 Other specific personality disorders	0.696	0.304	0.000
F60.4 Histrionic personality disorder	0.696	0.304	0.000
F60.2 Dissocial personality disorder	0.696	0.304	0.000
F60.1 Schizoid personality disorder	0.696	0.304	0.000
F60.0 Paranoid personality disorder	0.696	0.304	0.000
I24.8 Other forms of acute ischaemic heart disease	0.696	0.304	0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.696	0.304	0.000
T79-T79 Certain early complications of trauma	0.696	0.304	0.000
T14 Injury of unspecified body region	0.696	0.304	0.000
H74 Other disorders of middle ear and mastoid	0.695	0.305	0.000
E14.9 Without complications	0.695	0.305	0.000
E86 Volume depletion	0.694	0.306	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.694	0.306	0.000
W05 Fall involving wheelchair	0.694	0.306	0.000
W13 Fall from, out of or through building or structure	0.693	0.307	0.000
F45.9 Somatoform disorder, unspecified	0.693	0.307	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.693	0.307	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.692	0.308	0.000
Y35-Y36 Legal intervention and operations of war	0.691	0.309	0.000
X85-X99 Assault	0.691	0.309	0.000
X30-X39 Exposure to forces of nature	0.691	0.309	0.000
W65-W74 Accidental drowning and submersion	0.691	0.309	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.691	0.309	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.691	0.309	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.691	0.309	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.690	0.310	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.690	0.310	0.000
F70-F79 Mental retardation	0.689	0.311	0.000
K52.1 Toxic gastro-enteritis and colitis	0.688	0.312	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.687	0.313	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.686	0.313	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.686	0.313	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.686	0.313	0.000
Y58 Bacterial vaccines	0.686	0.314	0.000
E14.6 With other specified complications	0.685	0.314	0.000
F42 Obsessive-compulsive disorder	0.685	0.315	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.684	0.316	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.684	0.316	0.000
E32 Diseases of thymus	0.684	0.316	0.000
E31 Polyglandular dysfunction	0.684	0.316	0.000
E30 Disorders of puberty, not elsewhere classified	0.684	0.316	0.000
H60-H62 Diseases of external ear	0.684	0.316	0.000
K91.1 Postgastric surgery syndromes	0.684	0.316	0.000
X60-X84 Intentional self-harm	0.684	0.316	0.000
E85.4 Organ-limited amyloidosis	0.682	0.318	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.681	0.319	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.681	0.319	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.679	0.321	0.000
I13 Hypertensive heart and renal disease	0.677	0.323	0.000
E78.8 Other disorders of lipoprotein metabolism	0.677	0.323	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.677	0.323	0.000
T42.3 Barbiturates	0.677	0.323	0.000
T42.2 Succinimides and oxazolidinediones	0.677	0.323	0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.677	0.323	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.676	0.324	0.000
I00-I02 Acute rheumatic fever	0.674	0.326	0.000
L02.0 Cutaneous abscess, furuncle and carbuncle of face	0.674	0.326	0.000
F32.8 Other depressive episodes	0.674	0.326	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.673	0.327	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.673	0.327	0.000
F51 Nonorganic sleep disorders	0.672	0.328	0.000
F01.1 Multi-infarct dementia	0.672	0.328	0.000
L03.9 Cellulitis, unspecified	0.672	0.328	0.000
Y44 Agents primarily affecting blood constituents	0.671	0.329	0.000
F64 Gender identity disorders	0.670	0.329	0.000
S00-S09 Injuries to the head	0.671	0.329	0.000
T78.9 Adverse effect, unspecified	0.668	0.331	0.000
E14.5 With peripheral circulatory complications	0.668	0.332	0.000
E88.1 Lipodystrophy, not elsewhere classified	0.668	0.332	0.000
H70 Mastoiditis and related conditions	0.668	0.332	0.000
F09 Unspecified organic or symptomatic mental disorder	0.668	0.332	0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.668	0.332	0.000
Y46.2 Hydantoin derivatives	0.668	0.332	0.000
T43.2 Other and unspecified antidepressants	0.667	0.333	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.667	0.333	0.000
E23 Hypofunction and other disorders of pituitary gland	0.666	0.334	0.000
W26 Contact with knife, sword or dagger	0.666	0.334	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.666	0.334	0.000
T40.5 Cocaine	0.665	0.335	0.000
W01 Fall on same level from slipping, tripping and stumbling	0.665	0.335	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.664	0.336	0.000
T38.1 Thyroid hormones and substitutes	0.662	0.338	0.000
H72.1 Attic perforation of tympanic membrane	0.661	0.338	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.661	0.339	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.661	0.339	0.000
F80 Specific developmental disorders of speech and language	0.660	0.340	0.000
H93.2 Other abnormal auditory perceptions	0.660	0.340	0.000
T47.0 Histamine H(2)-receptor antagonists	0.659	0.341	0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.658	0.342	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.658	0.342	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.658	0.342	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.658	0.342	0.000
E89.5 Postprocedural testicular hypofunction	0.658	0.342	0.000
W09 Fall involving playground equipment	0.657	0.342	0.000
E78.1 Pure hyperglyceridaemia	0.656	0.343	0.000
E73 Lactose intolerance	0.656	0.344	0.000
W15.9 Unspecified place	0.655	0.344	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.655	0.345	0.000
T40.1 Heroin	0.655	0.345	0.000
H73.1 Chronic myringitis	0.654	0.345	0.000
H73.0 Acute myringitis	0.654	0.345	0.000
W14 Fall from tree	0.653	0.347	0.000
E28.2 Polycystic ovarian syndrome	0.653	0.347	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.652	0.347	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.652	0.347	0.000
S33.2 Dislocation of sacro-iliac and sacrococcygeal joint	0.652	0.348	0.000
S02 Fracture of skull and facial bones	0.652	0.348	0.000
T71 Asphyxiation	0.650	0.349	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.650	0.350	0.000
S36 Injury of intra-abdominal organs	0.650	0.350	0.000
Y40.4 Tetracyclines	0.650	0.350	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.649	0.351	0.000
I15 Secondary hypertension	0.649	0.351	0.000
F44.5 Dissociative convulsions	0.649	0.351	0.000
S32.2 Fracture of coccyx	0.649	0.351	0.000
E88.8 Other specified metabolic disorders	0.649	0.351	0.000
F45.4 Persistent somatoform pain disorder	0.648	0.352	0.000
F45.1 Undifferentiated somatoform disorder	0.648	0.352	0.000
S43.1 Dislocation of acromioclavicular joint	0.648	0.352	0.000
F00 Dementia in Alzheimer's disease	0.648	0.352	0.000
Q21.1 Atrial septal defect	0.648	0.352	0.000
F43.8 Other reactions to severe stress	0.647	0.352	0.000
W00 Fall on same level involving ice and snow	0.647	0.353	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.646	0.354	0.000
E14.7 With multiple complications	0.644	0.356	0.000
E14.2 Withrenal complications	0.644	0.356	0.000
E14.0 With coma	0.644	0.356	0.000
S48 Traumatic amputation of shoulder and upper arm	0.644	0.356	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.644	0.356	0.000
S44 Injury of nerves at shoulder and upper arm level	0.644	0.356	0.000
S47 Crushing injury of shoulder and upper arm	0.644	0.356	0.000
F06.8 Other specified mental disorders due to brain damage and dysfunction and to physical disease	0.643	0.356	0.000
K91.5 Postcholecystectomy syndrome	0.643	0.357	0.000
T36.9 Systemic antibiotic, unspecified	0.643	0.357	0.000
T36.8 Other systemic antibiotics	0.643	0.357	0.000
T36.7 Antifungal antibiotics, systemically used	0.643	0.357	0.000
T36.6 Rifamycins	0.643	0.357	0.000
T36.5 Aminoglycosides	0.643	0.357	0.000
T36.4 Tetracyclines	0.643	0.357	0.000
T36.3 Macrolides	0.643	0.357	0.000
T36.2 Chloramphenicol group	0.643	0.357	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.643	0.357	0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.643	0.357	0.000
T11.1 Open wound of upper limb, level unspecified	0.643	0.357	0.000
W29 Contact with other powered hand tools and household machinery	0.643	0.357	0.000
W17.6 Industrial and construction area	0.641	0.359	0.000
S33.1 Dislocation of lumbar vertebra	0.641	0.359	0.000
I09 Other rheumatic heart diseases	0.641	0.359	0.000
S32.5 Fracture of pubis	0.641	0.359	0.000
E20.9 Hypoparathyroidism, unspecified	0.640	0.360	0.000
S42.4 Fracture of lower end of humerus	0.640	0.360	0.000
E10.2 With renal complications	0.639	0.360	0.000
L04.1 Acute lymphadenitis of trunk	0.639	0.361	0.000
V18.3 Person injured while boarding or alighting	0.639	0.361	0.000
F44.4 Dissociative motor disorders	0.638	0.362	0.000
Y40.7 Antifungal antibiotics, systemically used	0.638	0.362	0.000
E85.8 Other amyloidosis	0.637	0.363	0.000
E85.2 Heredofamilial amyloidosis, unspecified	0.637	0.363	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.637	0.363	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.637	0.363	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations