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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant cluster associations

Hospitalization Episode Statistics (HES)

Cluster X0053
log Bayes Factor = 218.825
contains 12 variants:
rs114218990
lBF = 11.793
Chr 1 : 48,501,029
rs12496072
lBF = 7.122
Chr 3 : 55,985,751
Affx-52367455
lBF = 8.854
Chr 5 : 43,543,259
rs12777
lBF = 7.664
Chr 5 : 131,671,662
rs116577322
lBF = 9.370
Chr 5 : 132,850,336
rs75158997
lBF = 16.314
Chr 7 : 33,796,970
rs75323949
lBF = 6.248
Chr 8 : 69,545,445
rs7386241
lBF = 16.888
Chr 8 : 139,240,856
rs34390775
lBF = 10.871
Chr 9 : 140,702,339
rs72850953
lBF = 8.103
Chr11 : 1,771,871
rs11021370
lBF = 5.869
Chr11 : 95,726,855
rs34265079
lBF = 11.149
Chr19 : 28,577,342
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
1.000 0.000 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
1.000 0.000 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
1.000 0.000 0.000
A30-A49 Other bacterial diseases
1.000 0.000 0.000
C15-C26 Malignant neoplasms of digestive organs
1.000 0.000 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
M80-M85 Disorders of bone density and structure
1.000 0.000 0.000
M86-M90 Other osteopathies
1.000 0.000 0.000
S60-S69 Injuries to the wrist and hand
1.000 0.000 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
1.000 0.000 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
1.000 0.000 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
1.000 0.000 0.000
Z70-Z76 Persons encountering health services in other circumstances
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
1.000 0.000 0.000
M25 Other joint disorders, not elsewhere classified
1.000 0.000 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
A41 Other septicaemia
1.000 0.000 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
1.000 0.000 0.000
Y43 Primarily systemic agents
1.000 0.000 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
1.000 0.000 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
1.000 0.000 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
1.000 0.000 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
1.000 0.000 0.000
D70-D77 Other diseases of blood and blood-forming organs
1.000 0.000 0.000
G90-G99 Other disorders of the nervous system
1.000 0.000 0.000
I95-I99 Other and unspecified disorders of the circulatory system
1.000 0.000 0.000
M89 Other disorders of bone
1.000 0.000 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
1.000 0.000 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
1.000 0.000 0.000
M24 Other specific joint derangements
1.000 0.000 0.000
T43.2 Other and unspecified antidepressants
1.000 0.000 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
1.000 0.000 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
1.000 0.000 0.000
M60-M63 Disorders of muscles
1.000 0.000 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
M62.8 Other specified disorders of muscle
1.000 0.000 0.000
T91 Sequelae of injuries of neck and trunk
0.999 0.001 0.000
M62 Other disorders of muscle
0.999 0.001 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.999 0.001 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.999 0.001 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.999 0.001 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.999 0.001 0.000
C21 Malignant neoplasm of anus and anal canal
0.999 0.001 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.999 0.001 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.999 0.001 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.999 0.001 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.999 0.001 0.000
C78.2 Secondary malignant neoplasm of pleura
0.999 0.001 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.999 0.001 0.000
W00-W19 Falls
0.999 0.001 0.000
M84 Disorders of continuity of bone
0.999 0.001 0.000
M89.8 Other specified disorders of bone
0.999 0.001 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.999 0.001 0.000
R45 Symptoms and signs involving emotional state
0.998 0.002 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.998 0.002 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.998 0.002 0.000
Y43.3 Other antineoplastic drugs
0.998 0.002 0.000
C51-C58 Malignant neoplasms of female genital organs
0.998 0.002 0.000
W20-W49 Exposure to inanimate mechanical forces
0.998 0.002 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.998 0.002 0.000
S64 Injury of nerves at wrist and hand level
0.997 0.003 0.000
D75 Other diseases of blood and blood-forming organs
0.997 0.003 0.000
R20 Disturbances of skin sensation
0.997 0.003 0.000
A40 Streptococcal septicaemia
0.997 0.003 0.000
M85 Other disorders of bone density and structure
0.997 0.003 0.000
F30-F39 Mood [affective] disorders
0.997 0.003 0.000
T39.1 4-Aminophenol derivatives
0.997 0.003 0.000
G70-G73 Diseases of myoneural junction and muscle
0.997 0.003 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.997 0.003 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.997 0.003 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.997 0.003 0.000
S50-S59 Injuries to the elbow and forearm
0.997 0.003 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.997 0.003 0.000
R23 Other skin changes
0.997 0.003 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.996 0.004 0.000
B35-B49 Mycoses
0.996 0.004 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.996 0.004 0.000
G95 Other diseases of spinal cord
0.996 0.004 0.000
Z63 Other problems related to primary support group, including family circumstances
0.996 0.004 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.996 0.004 0.000
S32 Fracture of lumbar spine and pelvis
0.996 0.004 0.000
M70-M79 Other soft tissue disorders
0.995 0.005 0.000
Z75 Problems related to medical facilities and other health care
0.995 0.005 0.000
T51 Toxic effect of alcohol
0.995 0.005 0.000
H18 Other disorders of cornea
0.995 0.005 0.000
W19 Unspecified fall
0.995 0.005 0.000
D80-D89 Certain disorders involving the immune mechanism
0.995 0.005 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.994 0.006 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.994 0.006 0.000
Z51.3 Blood transfusion without reported diagnosis
0.994 0.006 0.000
Z51 Other medical care
0.994 0.006 0.000
T51.0 Ethanol
0.993 0.007 0.000
Q80-Q89 Other congenital malformations
0.993 0.007 0.000
K70-K77 Diseases of liver
0.993 0.007 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.993 0.007 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.993 0.007 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.993 0.007 0.000
C92 Myeloid leukaemia
0.992 0.008 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.992 0.008 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.991 0.009 0.000
O85-O92 Complications predominantly related to the puerperium
0.991 0.009 0.000
R29.6 Tendency to fall, not elsewhere classified
0.991 0.009 0.000
H30-H36 Disorders of choroid and retina
0.990 0.010 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.990 0.010 0.000
Z76 Persons encountering health services in other circumstances
0.989 0.011 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.989 0.011 0.000
G71 Primary disorders of muscles
0.989 0.011 0.000
C17 Malignant neoplasm of small intestine
0.989 0.011 0.000
I05-I09 Chronic rheumatic heart diseases
0.988 0.012 0.000
S90-S99 Injuries to the ankle and foot
0.988 0.012 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.988 0.012 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.988 0.012 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.988 0.012 0.000
L20-L30 Dermatitis and eczema
0.987 0.013 0.000
M21 Other acquired deformities of limbs
0.987 0.013 0.000
I85 Oesophageal varices
0.987 0.013 0.000
K73 Chronic hepatitis, not elsewhere classified
0.987 0.013 0.000
T91.3 Sequelae of injury of spinal cord
0.987 0.013 0.000
K74 Fibrosis and cirrhosis of liver
0.987 0.013 0.000
C21.1 Anal canal
0.987 0.013 0.000
S61 Open wound of wrist and hand
0.987 0.013 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.986 0.014 0.000
W50-W64 Exposure to animate mechanical forces
0.986 0.014 0.000
R23.8 Other and unspecified skin changes
0.986 0.014 0.000
O24 Diabetes mellitus in pregnancy
0.986 0.014 0.000
M25.8 Other specified joint disorders
0.986 0.014 0.000
R25 Abnormal involuntary movements
0.986 0.014 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.985 0.015 0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)
0.985 0.015 0.000
E20-E35 Disorders of other endocrine glands
0.985 0.015 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.984 0.016 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.984 0.016 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.984 0.016 0.000
B00 Herpesviral [herpes simplex] infections
0.984 0.016 0.000
C45 Mesothelioma
0.984 0.016 0.000
G95.8 Other specified diseases of spinal cord
0.983 0.017 0.000
C21.0 Anus, unspecified
0.983 0.017 0.000
Z74 Problems related to care-provider dependency
0.983 0.017 0.000
W19.3 Sports and athletics area
0.983 0.017 0.000
D80 Immunodeficiency with predominantly antibody defects
0.983 0.017 0.000
F33 Recurrent depressive disorder
0.982 0.018 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.982 0.018 0.000
E00-E07 Disorders of thyroid gland
0.982 0.018 0.000
R25.8 Other and unspecified abnormal involuntary movements
0.981 0.019 0.000
S10-S19 Injuries to the neck
0.981 0.019 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.981 0.019 0.000
Z45 Adjustment and management of implanted device
0.981 0.019 0.000
R73 Elevated blood glucose level
0.981 0.019 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.981 0.019 0.000
C81 Hodgkin's disease
0.980 0.020 0.000
Q60-Q64 Congenital malformations of the urinary system
0.980 0.020 0.000
T23 Burn and corrosion of wrist and hand
0.980 0.020 0.000
M25.7 Osteophyte
0.980 0.020 0.000
K75 Other inflammatory liver diseases
0.980 0.020 0.000
Y43.4 Immunosuppressive agents
0.980 0.020 0.000
F30 Manic episode
0.979 0.021 0.000
F02 Dementia in other diseases classified elsewhere
0.979 0.021 0.000
B15-B19 Viral hepatitis
0.979 0.021 0.000
H31 Other disorders of choroid
0.979 0.021 0.000
H33 Retinal detachments and breaks
0.979 0.021 0.000
M62.80 Other specified disorders of muscle (Multiple sites)
0.978 0.022 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.977 0.023 0.000
R20.2 Paraesthesia of skin
0.977 0.023 0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems
0.976 0.024 0.000
O21 Excessive vomiting in pregnancy
0.976 0.024 0.000
M89.87 Other specified disorders of bone (Ankle and foot)
0.976 0.024 0.000
M62.89 Other specified disorders of muscle (Site unspecified)
0.976 0.024 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.976 0.024 0.000
Z45.2 Adjustment and management of vascular access device
0.975 0.025 0.000
Q76 Congenital malformations of spine and bony thorax
0.975 0.025 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.975 0.025 0.000
M85.8 Other specified disorders of bone density and structure
0.975 0.025 0.000
G60 Hereditary and idiopathic neuropathy
0.974 0.026 0.000
R45.1 Restlessness and agitation
0.974 0.026 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.974 0.026 0.000
D80.1 Nonfamilial hypogammaglobulinaemia
0.974 0.026 0.000
T79-T79 Certain early complications of trauma
0.974 0.026 0.000
M80 Osteoporosis with pathological fracture
0.974 0.026 0.000
D73 Diseases of spleen
0.974 0.026 0.000
R23.1 Pallor
0.973 0.027 0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more
0.973 0.027 0.000
O32.2 Maternal care for transverse and oblique lie
0.973 0.027 0.000
R94 Abnormal results of function studies
0.972 0.028 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.972 0.028 0.000
Z56 Problems related to employment and unemployment
0.972 0.028 0.000
K70 Alcoholic liver disease
0.972 0.028 0.000
G30-G32 Other degenerative diseases of the nervous system
0.971 0.029 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.971 0.029 0.000
C78.0 Secondary malignant neoplasm of lung
0.971 0.029 0.000
L50-L54 Urticaria and erythema
0.970 0.030 0.000
I82 Other venous embolism and thrombosis
0.970 0.030 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.970 0.030 0.000
X60-X84 Intentional self-harm
0.969 0.031 0.000
H33.3 Retinal breaks without detachment
0.969 0.031 0.000
I85.9 Oesophageal varices without bleeding
0.969 0.031 0.000
H25-H28 Disorders of lens
0.968 0.032 0.000
H46 Optic neuritis
0.968 0.032 0.000
G83 Other paralytic syndromes
0.968 0.032 0.000
C92.0 Acute myeloid leukaemia
0.966 0.034 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.966 0.034 0.000
O12.0 Gestational oedema
0.966 0.034 0.000
M85.0 Fibrous dysplasia (monostotic)
0.966 0.034 0.000
R77 Other abnormalities of plasma proteins
0.966 0.034 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.966 0.034 0.000
W19.1 Residential institution
0.965 0.035 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.965 0.035 0.000
M25.3 Other instability of joint
0.965 0.035 0.000
T46.1 Calcium-channel blockers
0.965 0.035 0.000
H18.9 Disorder of cornea, unspecified
0.965 0.035 0.000
Q87.4 Marfan's syndrome
0.964 0.036 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.964 0.036 0.000
E27 Other disorders of adrenal gland
0.964 0.036 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.964 0.036 0.000
S56 Injury of muscle and tendon at forearm level
0.963 0.037 0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
0.963 0.037 0.000
I05 Rheumatic mitral valve diseases
0.963 0.037 0.000
G51 Facial nerve disorders
0.963 0.037 0.000
M90 Osteopathies in diseases classified elsewhere
0.963 0.037 0.000
X58 Exposure to other specified factors
0.963 0.037 0.000
Q50-Q56 Congenital malformations of genital organs
0.962 0.038 0.000
R94.5 Abnormal results of liver function studies
0.962 0.038 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.962 0.038 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.962 0.038 0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium
0.961 0.039 0.000
M25.74 Osteophyte (Hand)
0.961 0.039 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.961 0.039 0.000
B02 Zoster [herpes zoster]
0.961 0.039 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.961 0.039 0.000
Z63.0 Problems in relationship with spouse or partner
0.961 0.039 0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level
0.961 0.039 0.000
R40 Somnolence, stupor and coma
0.960 0.040 0.000
G82 Paraplegia and tetraplegia
0.960 0.040 0.000
R71 Abnormality of red blood cells
0.960 0.040 0.000
H31.0 Chorioretinal scars
0.959 0.041 0.000
M21.2 Flexion deformity
0.959 0.041 0.000
I72 Other aneurysm
0.959 0.041 0.000
Z73 Problems related to life-management difficulty
0.958 0.042 0.000
G71.1 Myotonic disorders
0.958 0.042 0.000
R73.0 Abnormal glucose tolerance test
0.958 0.042 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.958 0.042 0.000
M89.86 Other specified disorders of bone (Lower leg)
0.958 0.042 0.000
I86 Varicose veins of other sites
0.957 0.043 0.000
Z75.3 Unavailability and inaccessibility of health-care facilities
0.957 0.043 0.000
T40.6 Other and unspecified narcotics
0.957 0.043 0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
0.957 0.043 0.000
Y57 Other and unspecified drugs and medicaments
0.957 0.043 0.000
T23.0 Burn of unspecified degree of wrist and hand
0.956 0.044 0.000
T92 Sequelae of injuries of upper limb
0.956 0.044 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.956 0.044 0.000
S32.5 Fracture of pubis
0.956 0.044 0.000
R47-R49 Symptoms and signs involving speech and voice
0.956 0.044 0.000
T45.5 Anticoagulants
0.956 0.044 0.000
S92 Fracture of foot, except ankle
0.955 0.045 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.955 0.045 0.000
B35 Dermatophytosis
0.955 0.045 0.000
K73.2 Chronic active hepatitis, not elsewhere classified
0.955 0.045 0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level
0.955 0.045 0.000
Z76.8 Persons encountering health services in other specified circumstances
0.955 0.045 0.000
X20-X29 Contact with venomous animals and plants
0.955 0.045 0.000
I60-I69 Cerebrovascular diseases
0.954 0.046 0.000
B91 Sequelae of poliomyelitis
0.954 0.046 0.000
O44 Placenta praevia
0.954 0.046 0.000
A40.3 Septicaemia due to Streptococcus pneumoniae
0.954 0.046 0.000
C49.2 Connective and soft tissue of lower limb, including hip
0.954 0.046 0.000
M45-M49 Spondylopathies
0.952 0.048 0.000
M91-M94 Chondropathies
0.952 0.048 0.000
H27 Other disorders of lens
0.950 0.050 0.000
M82 Osteoporosis in diseases classified elsewhere
0.950 0.050 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.950 0.050 0.000
R45.2 Unhappiness
0.950 0.050 0.000
B49 Unspecified mycosis
0.949 0.051 0.000
A40.0 Septicaemia due to streptococcus, group A
0.949 0.051 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.949 0.051 0.000
S64.2 Injury of radial nerve at wrist and hand level
0.949 0.051 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.949 0.051 0.000
K73.9 Chronic hepatitis, unspecified
0.949 0.051 0.000
K74.6 Other and unspecified cirrhosis of liver
0.948 0.052 0.000
S61.1 Open wound of finger(s) with damage to nail
0.948 0.052 0.000
G60.0 Hereditary motor and sensory neuropathy
0.948 0.052 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.947 0.053 0.000
G95.1 Vascular myelopathies
0.947 0.053 0.000
M65-M68 Disorders of synovium and tendon
0.947 0.053 0.000
B35.1 Tinea unguium
0.946 0.054 0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent
0.946 0.054 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.946 0.054 0.000
S31 Open wound of abdomen, lower back and pelvis
0.945 0.055 0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)
0.945 0.055 0.000
Q12 Congenital lens malformations
0.945 0.055 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.944 0.056 0.000
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)
0.944 0.056 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.944 0.056 0.000
X58.9 Unspecified place
0.944 0.056 0.000
I82.9 Embolism and thrombosis of unspecified vein
0.944 0.056 0.000
T91.8 Sequelae of other specified injuries of neck and trunk
0.944 0.056 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.944 0.056 0.000
F02.3 Dementia in Parkinson's disease
0.944 0.056 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.943 0.057 0.000
C91 Lymphoid leukaemia
0.943 0.057 0.000
B01 Varicella [chickenpox]
0.943 0.057 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.942 0.058 0.000
C02.9 Tongue, unspecified
0.942 0.058 0.000
O14.0 Moderate preeclampsia
0.941 0.059 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.941 0.059 0.000
C16 Malignant neoplasm of stomach
0.941 0.059 0.000
D75.1 Secondary polycythaemia
0.941 0.059 0.000
C17.2 Ileum
0.941 0.059 0.000
V40-V49 Car occupant injured in transport accident
0.940 0.060 0.000
C45.9 Mesothelioma, unspecified
0.940 0.060 0.000
Y42.7 Androgens and anabolic congeners
0.940 0.060 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.940 0.060 0.000
H33.2 Serous retinal detachment
0.940 0.060 0.000
C53 Malignant neoplasm of cervix uteri
0.940 0.060 0.000
E06 Thyroiditis
0.940 0.060 0.000
O21.0 Mild hyperemesis gravidarum
0.940 0.060 0.000
E07 Other disorders of thyroid
0.939 0.061 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.939 0.061 0.000
O40 Polyhydramnios
0.939 0.061 0.000
C81.9 Hodgkin's disease, unspecified
0.939 0.061 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.938 0.062 0.000
R17 Unspecified jaundice
0.938 0.062 0.000
D75.2 Essential thrombocytosis
0.938 0.062 0.000
Z56.0 Unemployment, unspecified
0.938 0.062 0.000
M80.5 Idiopathic osteoporosis with pathological fracture
0.938 0.062 0.000
E03 Other hypothyroidism
0.937 0.063 0.000
S64.3 Injury of digital nerve of thumb
0.937 0.063 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.937 0.063 0.000
Q76.0 Spina bifida occulta
0.937 0.063 0.000
T66-T78 Other and unspecified effects of external causes
0.937 0.063 0.000
S32.1 Fracture of sacrum
0.936 0.064 0.000
M90.7 Fracture of bone in neoplastic disease
0.936 0.064 0.000
O32.4 Maternal care for high head at term
0.935 0.065 0.000
M24.5 Contracture of joint
0.935 0.065 0.000
I86.8 Varicose veins of other specified sites
0.935 0.065 0.000
Z73.9 Problem related to life-management difficulty, unspecified
0.935 0.065 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.935 0.065 0.000
W19.2 School, other institution and public administrative area
0.935 0.065 0.000
I27 Other pulmonary heart diseases
0.935 0.065 0.000
B44 Aspergillosis
0.935 0.065 0.000
R49 Voice disturbances
0.935 0.065 0.000
R45.8 Other symptoms and signs involving emotional state
0.934 0.066 0.000
M81 Osteoporosis without pathological fracture
0.933 0.067 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.933 0.067 0.000
L51 Erythema multiforme
0.933 0.067 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.932 0.068 0.000
K70.9 Alcoholic liver disease, unspecified
0.932 0.068 0.000
I97.1 Other functional disturbances following cardiac surgery
0.931 0.069 0.000
M87 Osteonecrosis
0.930 0.070 0.000
A46 Erysipelas
0.930 0.070 0.000
Q82 Other congenital malformations of skin
0.930 0.070 0.000
C48.1 Specified parts of peritoneum
0.930 0.070 0.000
G90 Disorders of autonomic nervous system
0.929 0.071 0.000
G72 Other myopathies
0.929 0.071 0.000
K75.4 Autoimmune hepatitis
0.929 0.071 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.929 0.071 0.000
E34 Other endocrine disorders
0.929 0.071 0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)
0.928 0.072 0.000
Q51 Congenital malformations of uterus and cervix
0.928 0.072 0.000
S32.50 Fracture of pubis (closed)
0.928 0.072 0.000
Z76.9 Persons encountering health services in unspecified circumstances
0.928 0.072 0.000
D75.9 Disease of blood and blood-forming organs, unspecified
0.927 0.073 0.000
C92.1 Chronic myeloid leukaemia
0.927 0.073 0.000
H18.1 Bullous keratopathy
0.926 0.074 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.926 0.074 0.000
E03.8 Other specified hypothyroidism
0.925 0.075 0.000
M85.80 Other specified disorders of bone density and structure (Multiple sites)
0.925 0.075 0.000
R21 Rash and other nonspecific skin eruption
0.925 0.075 0.000
K70.0 Alcoholic fatty liver
0.925 0.075 0.000
C23 Malignant neoplasm of gallbladder
0.925 0.075 0.000
L29 Pruritus
0.924 0.076 0.000
T40.4 Other synthetic narcotics
0.924 0.076 0.000
S52 Fracture of forearm
0.923 0.077 0.000
F01 Vascular dementia
0.923 0.077 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.923 0.077 0.000
M25.84 Other specified joint disorders (Hand)
0.923 0.077 0.000
W55 Bitten or struck by other mammals
0.923 0.077 0.000
X23 Contact with hornets, wasps and bees
0.922 0.078 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.922 0.078 0.000
R46 Symptoms and signs involving appearance and behaviour
0.922 0.078 0.000
G51.9 Disorder of facial nerve, unspecified
0.922 0.078 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.922 0.078 0.000
G54 Nerve root and plexus disorders
0.922 0.078 0.000
S65 Injury of blood vessels at wrist and hand level
0.921 0.079 0.000
S66.8 Injury of other muscles and tendons at wrist and hand level
0.921 0.079 0.000
B25-B34 Other viral diseases
0.921 0.079 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.921 0.079 0.000
T45.0 Antiallergic and antiemetic drugs
0.921 0.079 0.000
D73.8 Other diseases of spleen
0.920 0.080 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.920 0.080 0.000
Y43.1 Antineoplastic antimetabolites
0.919 0.081 0.000
E27.8 Other specified disorders of adrenal gland
0.919 0.081 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.919 0.081 0.000
L21 Seborrhoeic dermatitis
0.919 0.081 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.919 0.081 0.000
W50 Hit, struck, kicked, twisted, bitten or scratched by another person
0.918 0.082 0.000
C25 Malignant neoplasm of pancreas
0.918 0.082 0.000
Q12.0 Congenital cataract
0.918 0.082 0.000
M25.9 Joint disorder, unspecified
0.918 0.082 0.000
R77.8 Other specified abnormalities of plasma proteins
0.918 0.082 0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
0.917 0.083 0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)
0.917 0.083 0.000
Z74.2 Need for assistance at home and no other household member able to render care
0.917 0.083 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.916 0.084 0.000
O87 Venous complications in the puerperium
0.916 0.084 0.000
W21 Striking against or struck by sports equipment
0.916 0.084 0.000
Y57.5 X-ray contrast media
0.915 0.085 0.000
Z58 Problems related to physical environment
0.915 0.085 0.000
O90 Complications of the puerperium, not elsewhere classified
0.915 0.085 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.915 0.085 0.000
I69 Sequelae of cerebrovascular disease
0.915 0.085 0.000
Z75.8 Other problems related to medical facilities and other health care
0.915 0.085 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.915 0.085 0.000
T20 Burn and corrosion of head and neck
0.915 0.085 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.914 0.086 0.000
M82.1 Osteoporosis in endocrine disorders
0.914 0.086 0.000
G95.0 Syringomyelia and syringobulbia
0.913 0.087 0.000
Chapter X Diseases of the respiratory system
0.913 0.087 0.000
C84.5 Other and unspecified T-cell lymphomas
0.913 0.087 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.913 0.087 0.000
O44.0 Placenta praevia specified as without haemorrhage
0.912 0.088 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.912 0.088 0.000
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)
0.912 0.088 0.000
I97.2 Postmastectomy lymphoedema syndrome
0.912 0.088 0.000
L52 Erythema nodosum
0.912 0.088 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.912 0.088 0.000
F30.9 Manic episode, unspecified
0.912 0.088 0.000
G71.0 Muscular dystrophy
0.911 0.089 0.000
G91 Hydrocephalus
0.911 0.089 0.000
B02.3 Zoster ocular disease
0.911 0.089 0.000
G80 Infantile cerebral palsy
0.910 0.090 0.000
I82.2 Embolism and thrombosis of vena cava
0.910 0.090 0.000
B16 Acute hepatitis B
0.910 0.090 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.910 0.090 0.000
S68 Traumatic amputation of wrist and hand
0.910 0.090 0.000
J95-J99 Other diseases of the respiratory system
0.909 0.091 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.907 0.093 0.000
X59 Exposure to unspecified factor
0.906 0.094 0.000
M25.34 Other instability of joint (Hand)
0.904 0.096 0.000
F02.8 Dementia in other specified diseases classified elsewhere
0.904 0.096 0.000
C57.0 Fallopian tube
0.904 0.096 0.000
T87 Complications peculiar to reattachment and amputation
0.904 0.096 0.000
A39 Meningococcal infection
0.904 0.096 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.903 0.097 0.000
B50-B64 Protozoal diseases
0.903 0.097 0.000
B01.9 Varicella without complications
0.903 0.097 0.000
A40.9 Streptococcal septicaemia, unspecified
0.902 0.098 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.902 0.098 0.000
C54 Malignant neoplasm of corpus uteri
0.902 0.098 0.000
R23.0 Cyanosis
0.902 0.098 0.000
Q00-Q07 Congenital malformations of the nervous system
0.902 0.098 0.000
Z74.8 Other problems related to care-provider dependency
0.902 0.098 0.000
Z46 Fitting and adjustment of other devices
0.901 0.099 0.000
C24.1 Ampulla of Vater
0.901 0.099 0.000
B02.2 Zoster with other nervous system involvement
0.900 0.100 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.900 0.100 0.000
M00-M03 Infectious arthropathies
0.900 0.100 0.000
H27.0 Aphakia
0.900 0.100 0.000
R82 Other abnormal findings in urine
0.900 0.100 0.000
S64.0 Injury of ulnar nerve at wrist and hand level
0.900 0.100 0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.900 0.100 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.899 0.101 0.000
M40-M43 Deforming dorsopathies
0.899 0.101 0.000
M24.2 Disorder of ligament
0.899 0.101 0.000
I07 Rheumatic tricuspid valve diseases
0.899 0.101 0.000
M21.0 Valgus deformity, not elsewhere classified
0.899 0.101 0.000
O60-O75 Complications of labour and delivery
0.898 0.102 0.000
L51.9 Erythema multiforme, unspecified
0.898 0.102 0.000
G20-G26 Extrapyramidal and movement disorders
0.897 0.103 0.000
J09-J18 Influenza and pneumonia
0.897 0.103 0.000
X68 Intentional self-poisoning by and exposure to pesticides
0.897 0.103 0.000
S13.4 Sprain and strain of cervical spine
0.897 0.103 0.000
K74.5 Biliary cirrhosis, unspecified
0.896 0.104 0.000
I27.0 Primary pulmonary hypertension
0.896 0.104 0.000
Q65 Congenital deformities of hip
0.895 0.105 0.000
S32.10 Fracture of sacrum (closed)
0.894 0.106 0.000
I62 Other nontraumatic intracranial haemorrhage
0.894 0.106 0.000
Z74.1 Need for assistance with personal care
0.894 0.106 0.000
I10-I15 Hypertensive diseases
0.894 0.106 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.894 0.106 0.000
C17.0 Duodenum
0.893 0.107 0.000
T86 Failure and rejection of transplanted organs and tissues
0.893 0.107 0.000
M70.2 Olecranon bursitis
0.892 0.108 0.000
X78 Intentional self-harm by sharp object
0.892 0.108 0.000
M21.26 Flexion deformity (Lower leg)
0.892 0.108 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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