TreeWAS – Variant ID: rs34390775

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter II Neoplasms	1.000	0.000
# Top node	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
Chapter VI Diseases of the nervous system	1.000	0.000
C15-C26 Malignant neoplasms of digestive organs	1.000	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.999	0.001
T36-T50 Poisoning by drugs, medicaments and biological substances	0.999	0.001
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.999	0.001
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.997	0.003
G90-G99 Other disorders of the nervous system	0.994	0.006
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.992	0.008
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.990	0.010
D10-D36 Benign neoplasms	0.989	0.011
S60-S69 Injuries to the wrist and hand	0.987	0.013
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.983	0.017
C19 Malignant neoplasm of rectosigmoid junction	0.981	0.019
G93 Other disorders of brain	0.980	0.020
D12.5 Sigmoid colon	0.979	0.021
R20 Disturbances of skin sensation	0.977	0.023
M20-M25 Other joint disorders	0.977	0.023
C83 Diffuse non-Hodgkin's lymphoma	0.976	0.024
C16 Malignant neoplasm of stomach	0.968	0.032
M25 Other joint disorders, not elsewhere classified	0.966	0.034
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.966	0.034
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.965	0.035
R20.8 Other and unspecified disturbances of skin sensation	0.952	0.048
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.951	0.049
M25.5 Pain in joint	0.949	0.051
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.944	0.056
C83.3 Large cell (diffuse)	0.943	0.057
D10 Benign neoplasm of mouth and pharynx	0.941	0.059
C20 Malignant neoplasm of rectum	0.935	0.065
G40-G47 Episodic and paroxysmal disorders	0.932	0.068
M70-M79 Other soft tissue disorders	0.926	0.074
M24 Other specific joint derangements	0.925	0.075
D12.4 Descending colon	0.925	0.075
G40 Epilepsy	0.922	0.078
C16.0 Cardia	0.919	0.081
M25.55 Pain in joint (Pelvic region and thigh)	0.918	0.082
M80-M85 Disorders of bone density and structure	0.917	0.083
G40.9 Epilepsy, unspecified	0.914	0.086
S64 Injury of nerves at wrist and hand level	0.912	0.088
G50-G59 Nerve, nerve root and plexus disorders	0.904	0.096
M75 Shoulder lesions	0.903	0.097
S66 Injury of muscle and tendon at wrist and hand level	0.902	0.098
G93.3 Postviral fatigue syndrome	0.898	0.102
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.893	0.107
T42.4 Benzodiazepines	0.892	0.108
S61 Open wound of wrist and hand	0.890	0.110
T39.1 4-Aminophenol derivatives	0.889	0.111
Chapter V Mental and behavioural disorders	0.887	0.113
C81 Hodgkin's disease	0.886	0.114
M25.56 Pain in joint (Lower leg)	0.884	0.116
R22.2 Localised swelling, mass and lump, trunk	0.880	0.120
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.879	0.121
G70-G73 Diseases of myoneural junction and muscle	0.873	0.127
M50-M54 Other dorsopathies	0.870	0.130
Chapter XX External causes of morbidity and mortality	0.869	0.131
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.867	0.133
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.865	0.134
R22.4 Localised swelling, mass and lump, lower limb	0.863	0.137
R50-R69 General symptoms and signs	0.861	0.139
C85.1 B-cell lymphoma, unspecified	0.856	0.144
R20.2 Paraesthesia of skin	0.853	0.147
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.853	0.147
M75.5 Bursitis of shoulder	0.852	0.148
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.852	0.148
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.849	0.151
G93.0 Cerebral cysts	0.849	0.151
R22.1 Localised swelling, mass and lump, neck	0.846	0.154
G91 Hydrocephalus	0.843	0.157
S20-S29 Injuries to the thorax	0.843	0.157
D10.3 Other and unspecified parts of mouth	0.842	0.158
S64.2 Injury of radial nerve at wrist and hand level	0.837	0.163
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.836	0.164
Chapter I Certain infectious and parasitic diseases	0.836	0.164
C15 Malignant neoplasm of oesophagus	0.834	0.166
M50 Cervical disk disorders	0.833	0.167
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.833	0.167
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.830	0.170
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.830	0.170
D10.1 Tongue	0.827	0.173
M84 Disorders of continuity of bone	0.823	0.177
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.822	0.178
G20-G26 Extrapyramidal and movement disorders	0.821	0.179
M24.1 Other articular cartilage disorders	0.820	0.180
G93.6 Cerebral oedema	0.820	0.180
D00-D09 In situ neoplasms	0.819	0.181
M25.59 Pain in joint (Site unspecified)	0.818	0.182
R02 Gangrene, not elsewhere classified	0.814	0.186
S65 Injury of blood vessels at wrist and hand level	0.813	0.187
S61.9 Open wound of wrist and hand, part unspecified	0.813	0.187
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.812	0.188
C21 Malignant neoplasm of anus and anal canal	0.812	0.188
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.810	0.190
S10-S19 Injuries to the neck	0.809	0.191
M40-M43 Deforming dorsopathies	0.809	0.191
M75.1 Rotator cuff syndrome	0.807	0.193
T79-T79 Certain early complications of trauma	0.802	0.198
C26 Malignant neoplasm of other and ill-defined digestive organs	0.800	0.200
T39.0 Salicylates	0.800	0.200
D28 Benign neoplasm of other and unspecified female genital organs	0.799	0.201
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.799	0.201
R63 Symptoms and signs concerning food and fluid intake	0.799	0.201
S30 Superficial injury of abdomen, lower back and pelvis	0.798	0.201
S61.1 Open wound of finger(s) with damage to nail	0.796	0.204
C91 Lymphoid leukaemia	0.794	0.205
F20 Schizophrenia	0.794	0.206
M25.3 Other instability of joint	0.792	0.208
R87 Abnormal findings in specimens from female genital organs	0.791	0.209
D12.6 Colon, unspecified	0.791	0.209
C83.0 Small cell (diffuse)	0.790	0.210
C92 Myeloid leukaemia	0.790	0.210
M25.8 Other specified joint disorders	0.789	0.211
M25.53 Pain in joint (Forearm)	0.788	0.212
G95 Other diseases of spinal cord	0.787	0.213
C16.9 Stomach, unspecified	0.787	0.213
T20-T25 Burns and corrosions of external body surface, specified by site	0.787	0.213
M65-M68 Disorders of synovium and tendon	0.786	0.214
D04 Carcinoma in situ of skin	0.786	0.214
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.784	0.216
G93.4 Encephalopathy, unspecified	0.783	0.217
G94 Other disorders of brain in diseases classified elsewhere	0.783	0.217
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.781	0.219
R63.0 Anorexia	0.779	0.221
R60 Oedema, not elsewhere classified	0.779	0.221
M60-M63 Disorders of muscles	0.778	0.222
M32 Systemic lupus erythematosus	0.777	0.223
M24.4 Recurrent dislocation and subluxation of joint	0.776	0.224
C16.5 Lesser curvature of stomach, unspecified	0.775	0.225
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.774	0.226
D32 Benign neoplasm of meninges	0.773	0.227
B25-B34 Other viral diseases	0.770	0.230
C90 Multiple myeloma and malignant plasma cell neoplasms	0.769	0.231
M50.2 Other cervical disk displacement	0.768	0.232
M45-M49 Spondylopathies	0.767	0.233
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.767	0.233
D36 Benign neoplasm of other and unspecified sites	0.766	0.234
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.766	0.234
M84.1 Nonunion of fracture [pseudarthrosis]	0.766	0.234
G59 Mononeuropathy in diseases classified elsewhere	0.765	0.235
S70-S79 Injuries to the hip and thigh	0.765	0.235
S62 Fracture at wrist and hand level	0.763	0.237
G00-G09 Inflammatory diseases of the central nervous system	0.762	0.238
D12.8 Rectum	0.760	0.240
G90 Disorders of autonomic nervous system	0.759	0.241
G30-G32 Other degenerative diseases of the nervous system	0.758	0.242
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.757	0.243
R04 Haemorrhage from respiratory passages	0.757	0.243
M25.7 Osteophyte	0.757	0.243
G93.8 Other specified disorders of brain	0.756	0.244
C83.1 Small cleaved cell (diffuse)	0.756	0.244
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.756	0.244
D26 Other benign neoplasms of uterus	0.756	0.244
C81.9 Hodgkin's disease, unspecified	0.756	0.244
G57 Mononeuropathies of lower limb	0.755	0.245
D30 Benign neoplasm of urinary organs	0.754	0.246
M25.52 Pain in joint (Upper arm)	0.754	0.246
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.754	0.246
A30-A49 Other bacterial diseases	0.751	0.249
G93.1 Anoxic brain damage, not elsewhere classified	0.750	0.250
G24 Dystonia	0.750	0.250
D12.1 Appendix	0.749	0.251
M91-M94 Chondropathies	0.746	0.254
Chapter IV Endocrine, nutritional and metabolic diseases	0.746	0.254
C23 Malignant neoplasm of gallbladder	0.745	0.255
C17 Malignant neoplasm of small intestine	0.743	0.257
G70 Myasthenia gravis and other myoneural disorders	0.741	0.259
Chapter XV Pregnancy, childbirth and the puerperium	0.739	0.261
D16 Benign neoplasm of bone and articular cartilage	0.739	0.261
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.739	0.261
M80 Osteoporosis with pathological fracture	0.739	0.261
R54 Senility	0.739	0.261
R87.6 Abnormal cytological findings	0.738	0.262
M75.3 Calcific tendinitis of shoulder	0.738	0.262
D29 Benign neoplasm of male genital organs	0.738	0.262
M30 Polyarteritis nodosa and related conditions	0.736	0.264
S32 Fracture of lumbar spine and pelvis	0.732	0.268
F20.9 Schizophrenia, unspecified	0.731	0.269
C81.1 Nodular sclerosis	0.730	0.270
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems	0.730	0.270
M75.2 Bicipital tendinitis	0.729	0.271
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.729	0.271
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.728	0.272
R80 Isolated proteinuria	0.727	0.273
T46 Poisoning by agents primarily affecting the cardiovascular system	0.724	0.276
S30.0 Contusion of lower back and pelvis	0.724	0.276
D10.0 Lip	0.724	0.276
G93.9 Disorder of brain, unspecified	0.723	0.277
E10-E14 Diabetes mellitus	0.723	0.277
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.722	0.278
G96 Other disorders of central nervous system	0.721	0.278
D12.9 Anus and anal canal	0.721	0.279
M24.8 Other specific joint derangements, not elsewhere classified	0.719	0.281
D22 Melanocytic naevi	0.718	0.282
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.718	0.282
G45 Transient cerebral ischaemic attacks and related syndromes	0.718	0.282
M25.0 Haemarthrosis	0.718	0.282
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.717	0.283
C40-C41 Malignant neoplasms of bone and articular cartilage	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.717	0.283
T40.6 Other and unspecified narcotics	0.716	0.284
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.716	0.284
C95 Leukaemia of unspecified cell type	0.716	0.284
C94 Other leukaemias of specified cell type	0.716	0.284
C93 Monocytic leukaemia	0.716	0.284
C88 Malignant immunoproliferative diseases	0.716	0.284
C86 Other specified types of T/NK-cell lymphoma	0.716	0.284
C84 Peripheral and cutaneous T-cell lymphomas	0.716	0.284
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.716	0.284
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.716	0.284
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.716	0.284
T41 Poisoning by anaesthetics and therapeutic gases	0.716	0.284
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.716	0.284
T36 Poisoning by systemic antibiotics	0.716	0.284
R61 Hyperhidrosis	0.716	0.284
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.715	0.284
D04.5 Skin of trunk	0.715	0.285
D34 Benign neoplasm of thyroid gland	0.715	0.285
R95-R99 Ill-defined and unknown causes of mortality	0.715	0.285
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.714	0.286
R82 Other abnormal findings in urine	0.714	0.286
T31 Burns classified according to extent of body surface involved	0.714	0.286
G98 Other disorders of nervous system, not elsewhere classified	0.713	0.287
G92 Toxic encephalopathy	0.713	0.287
M50.3 Other cervical disk degeneration	0.712	0.288
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.712	0.288
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.710	0.290
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.710	0.290
T39.4 Antirheumatics, not elsewhere classified	0.710	0.290
T39.2 Pyrazolone derivatives	0.710	0.290
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.709	0.291
D31 Benign neoplasm of eye and adnexa	0.709	0.291
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.709	0.291
D19 Benign neoplasm of mesothelial tissue	0.709	0.291
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.709	0.291
C07 Malignant neoplasm of parotid gland	0.708	0.292
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.707	0.293
S67 Crushing injury of wrist and hand	0.707	0.293
R04.0 Epistaxis	0.707	0.293
D14 Benign neoplasm of middle ear and respiratory system	0.707	0.293
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.705	0.295
G51 Facial nerve disorders	0.704	0.296
M77 Other enthesopathies	0.704	0.296
M24.16 Other articular cartilage disorders (Lower leg)	0.703	0.297
G93.7 Reye's syndrome	0.703	0.297
G93.5 Compression of brain	0.703	0.297
G93.2 Benign intracranial hypertension	0.703	0.297
S64.4 Injury of digital nerve of other finger	0.702	0.298
R23 Other skin changes	0.701	0.299
T80 Complications following infusion, transfusion and therapeutic injection	0.701	0.299
M47 Spondylosis	0.701	0.299
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.701	0.299
G91.0 Communicating hydrocephalus	0.700	0.299
X20-X29 Contact with venomous animals and plants	0.700	0.300
R20.3 Hyperaesthesia	0.700	0.300
R20.1 Hypoaesthesia of skin	0.700	0.300
R20.0 Anaesthesia of skin	0.700	0.300
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.700	0.300
M33 Dermatopolymyositis	0.700	0.300
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.700	0.300
C83.7 Burkitt's tumour	0.700	0.300
C83.6 Undifferentiated (diffuse)	0.700	0.300
C83.5 Lymphoblastic (diffuse)	0.700	0.300
C83.4 Immunoblastic (diffuse)	0.700	0.300
C83.2 Mixed small and large cell (diffuse)	0.700	0.300
B34 Viral infection of unspecified site	0.700	0.300
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.699	0.301
R68 Other general symptoms and signs	0.698	0.302
G54 Nerve root and plexus disorders	0.697	0.303
S68 Traumatic amputation of wrist and hand	0.697	0.303
F99-F99 Unspecified mental disorder	0.696	0.304
D11 Benign neoplasm of major salivary glands	0.695	0.305
M24.0 Loose body in joint	0.695	0.305
D17 Benign lipomatous neoplasm	0.695	0.305
M00-M03 Infectious arthropathies	0.694	0.306
C16.8 Overlapping lesion of stomach	0.694	0.306
C16.6 Greater curvature of stomach, unspecified	0.694	0.306
C16.4 Pylorus	0.694	0.306
C16.3 Pyloric antrum	0.694	0.306
C16.2 Body of stomach	0.694	0.306
C16.1 Fundus of stomach	0.694	0.306
M25.2 Flail joint	0.693	0.307
M25.1 Fistula of joint	0.693	0.307
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.693	0.307
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.693	0.307
T42.5 Mixed antiepileptics, not elsewhere classified	0.693	0.307
T42.3 Barbiturates	0.693	0.307
T42.2 Succinimides and oxazolidinediones	0.693	0.307
T42.1 Iminostilbenes	0.693	0.307
T42.0 Hydantoin derivatives	0.693	0.307
S64.3 Injury of digital nerve of thumb	0.692	0.308
T86 Failure and rejection of transplanted organs and tissues	0.690	0.310
R60.0 Localised oedema	0.690	0.310
S65.1 Injury of radial artery at wrist and hand level	0.688	0.312
M24.2 Disorder of ligament	0.688	0.312
M25.6 Stiffness of joint, not elsewhere classified	0.688	0.312
R09.0 Asphyxia	0.687	0.313
M86-M90 Other osteopathies	0.687	0.313
M81 Osteoporosis without pathological fracture	0.687	0.313
G56 Mononeuropathies of upper limb	0.687	0.313
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.686	0.313
M75.9 Shoulder lesion, unspecified	0.686	0.314
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.685	0.315
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.685	0.315
Q80-Q89 Other congenital malformations	0.684	0.316
G71 Primary disorders of muscles	0.683	0.317
S27 Injury of other and unspecified intrathoracic organs	0.682	0.318
R22.7 Localised swelling, mass and lump, multiple sites	0.681	0.318
F60-F69 Disorders of adult personality and behaviour	0.681	0.319
M25.58 Pain in joint (Other)	0.681	0.319
O47 False labour	0.680	0.320
X58-X59 Accidental exposure to other and unspecified factors	0.679	0.321
G50 Disorders of trigeminal nerve	0.679	0.321
E11 Non-insulin-dependent diabetes mellitus	0.679	0.321
F22 Persistent delusional disorders	0.678	0.322
C21.1 Anal canal	0.678	0.322
C15.9 Oesophagus, unspecified	0.677	0.323
C85.7 Other specified types of non-Hodgkin's lymphoma	0.676	0.323
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.676	0.323
C85.0 Lymphosarcoma	0.676	0.323
M25.86 Other specified joint disorders (Lower leg)	0.675	0.325
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.675	0.325
D10.9 Pharynx, unspecified	0.675	0.325
D10.7 Hypopharynx	0.675	0.325
D10.6 Nasopharynx	0.675	0.325
D10.5 Other parts of oropharynx	0.675	0.325
D10.4 Tonsil	0.675	0.325
D10.2 Floor of mouth	0.675	0.325
Chapter X Diseases of the respiratory system	0.675	0.325
M82 Osteoporosis in diseases classified elsewhere	0.674	0.326
M25.54 Pain in joint (Hand)	0.674	0.326
M47.8 Other spondylosis	0.674	0.326
G57.8 Other mononeuropathies of lower limb	0.673	0.327
R56 Convulsions, not elsewhere classified	0.673	0.327
E20-E35 Disorders of other endocrine glands	0.672	0.328
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.669	0.330
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.669	0.331
G58 Other mononeuropathies	0.669	0.331
M34 Systemic sclerosis	0.669	0.331
G99 Other disorders of nervous system in diseases classified elsewhere	0.668	0.331
G46 Vascular syndromes of brain in cerebrovascular diseases	0.668	0.332
D04.3 Skin of other and unspecified parts of face	0.668	0.332
R59 Enlarged lymph nodes	0.667	0.333
G59.0 Diabetic mononeuropathy	0.667	0.333
M25.31 Other instability of joint (Shoulder region)	0.666	0.334
C09 Malignant neoplasm of tonsil	0.666	0.334
J95-J99 Other diseases of the respiratory system	0.666	0.334
R19 Other symptoms and signs involving the digestive system and abdomen	0.665	0.335
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.665	0.335
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.664	0.335
M47.82 Other spondylosis (Cervical region)	0.665	0.335
T66-T78 Other and unspecified effects of external causes	0.664	0.336
M22 Disorders of patella	0.664	0.336
S61.7 Multiple open wounds of wrist and hand	0.664	0.336
M76 Enthesopathies of lower limb, excluding foot	0.664	0.336
M73 Soft tissue disorders in diseases classified elsewhere	0.664	0.336
G91.9 Hydrocephalus, unspecified	0.663	0.337
M24.9 Joint derangement, unspecified	0.663	0.337
M24.7 Protrusio acetabuli	0.663	0.337
M24.6 Ankylosis of joint	0.663	0.337
M24.5 Contracture of joint	0.663	0.337
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.663	0.337
R72 Abnormality of white blood cells, not elsewhere classified	0.662	0.338
G40.8 Other epilepsy	0.661	0.339
G40.7 Petit mal, unspecified, without grand mal seizures	0.661	0.339
G40.5 Special epileptic syndromes	0.661	0.339
G40.4 Other generalised epilepsy and epileptic syndromes	0.661	0.339
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.661	0.339
M25.9 Joint disorder, unspecified	0.661	0.339
T79 Certain early complications of trauma, not elsewhere classified	0.661	0.339
J98 Other respiratory disorders	0.661	0.339
B90-B94 Sequelae of infectious and parasitic diseases	0.660	0.340
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.660	0.340
C92.1 Chronic myeloid leukaemia	0.659	0.341
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.659	0.341
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.658	0.342
M83 Adult osteomalacia	0.658	0.342
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.658	0.342
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.657	0.343
D04.7 Skin of lower limb, including hip	0.657	0.343
S69 Other and unspecified injuries of wrist and hand	0.657	0.343
C26.0 Intestinal tract, part unspecified	0.657	0.343
M25.71 Osteophyte (Shoulder region)	0.657	0.343
C15.5 Lower third of oesophagus	0.656	0.344
T85 Complications of other internal prosthetic devices, implants and grafts	0.655	0.345
F23 Acute and transient psychotic disorders	0.655	0.345
R58 Haemorrhage, not elsewhere classified	0.655	0.345
J98.1 Pulmonary collapse	0.655	0.345
D22.6 Melanocytic naevi of upper limb, including shoulder	0.655	0.345
X40-X49 Accidental poisoning by and exposure to noxious substances	0.654	0.345
S64.9 Injury of unspecified nerve at wrist and hand level	0.654	0.346
S64.8 Injury of other nerves at wrist and hand level	0.654	0.346
S64.7 Injury of multiple nerves at wrist and hand level	0.654	0.346
S64.1 Injury of median nerve at wrist and hand level	0.654	0.346
D12.0 Caecum	0.653	0.347
M66 Spontaneous rupture of synovium and tendon	0.652	0.348
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.652	0.348
G41 Status epilepticus	0.651	0.349
F25 Schizoaffective disorders	0.650	0.349
G72 Other myopathies	0.650	0.350
G35-G37 Demyelinating diseases of the central nervous system	0.650	0.350
S20 Superficial injury of thorax	0.649	0.351
Y41 Other systemic anti-infectives and antiparasitics	0.649	0.351
Y44 Agents primarily affecting blood constituents	0.649	0.351
Q20-Q28 Congenital malformations of the circulatory system	0.649	0.351
B34.9 Viral infection, unspecified	0.649	0.351
A00-A09 Intestinal infectious diseases	0.649	0.351
C91.1 Chronic lymphocytic leukaemia	0.648	0.352
G53 Cranial nerve disorders in diseases classified elsewhere	0.648	0.352
G52 Disorders of other cranial nerves	0.648	0.352
M75.8 Other shoulder lesions	0.648	0.352
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.648	0.352
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.647	0.353
R22.3 Localised swelling, mass and lump, upper limb	0.647	0.353
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.647	0.353
G70.0 Myasthenia gravis	0.647	0.353
S66.8 Injury of other muscles and tendons at wrist and hand level	0.647	0.353
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.647	0.353
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.647	0.353
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.647	0.353
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.647	0.353
F20.0 Paranoid schizophrenia	0.646	0.353
T51 Toxic effect of alcohol	0.646	0.353
Y52 Agents primarily affecting the cardiovascular system	0.646	0.354
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.646	0.354
Chapter VII Diseases of the eye and adnexa	0.646	0.354
O20-O29 Other maternal disorders predominantly related to pregnancy	0.645	0.355
S64.0 Injury of ulnar nerve at wrist and hand level	0.643	0.357
O42 Premature rupture of membranes	0.643	0.357
R19.5 Other fecal abnormalities	0.642	0.358
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.641	0.359
O47.1 False labour at or after 37 completed weeks of gestation	0.641	0.359
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.640	0.360
S37 Injury of urinary and pelvic organs	0.640	0.360
S36 Injury of intra-abdominal organs	0.640	0.360
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.640	0.360
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.640	0.360
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.640	0.360
S31 Open wound of abdomen, lower back and pelvis	0.640	0.360
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.640	0.360
G24.5 Blepharospasm	0.640	0.360
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.639	0.361
D21 Other benign neoplasms of connective and other soft tissue	0.639	0.361
M43 Other deforming dorsopathies	0.639	0.361
R21 Rash and other nonspecific skin eruption	0.638	0.362
S22 Fracture of rib(s), sternum and thoracic spine	0.638	0.362
T15-T19 Effects of foreign body entering through natural orifice	0.637	0.363
M71 Other bursopathies	0.637	0.363
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.637	0.363
M21 Other acquired deformities of limbs	0.636	0.364
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.636	0.364
F80-F89 Disorders of psychological development	0.636	0.364
F70-F79 Mental retardation	0.636	0.364
F29 Unspecified nonorganic psychosis	0.636	0.364
M85 Other disorders of bone density and structure	0.635	0.365
C81.7 Other Hodgkin's disease	0.635	0.365
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.635	0.365
C81.3 Lymphocytic depletion	0.635	0.365
C81.2 Mixed cellularity	0.635	0.365
C81.0 Lymphocytic predominance	0.635	0.365
M32.1 Systemic lupus erythematosus with organ or system involvement	0.634	0.366
T20 Burn and corrosion of head and neck	0.634	0.366
R09.3 Abnormal sputum	0.633	0.367
M31 Other necrotising vasculopathies	0.633	0.367
R74 Abnormal serum enzyme levels	0.633	0.367
D28.1 Vagina	0.633	0.367
M50.0 Cervical disk disorder with myelopathy	0.632	0.368
G95.0 Syringomyelia and syringobulbia	0.632	0.368
D23 Other benign neoplasms of skin	0.632	0.368
R09.1 Pleurisy	0.632	0.368
G45.4 Transient global amnesia	0.632	0.368
V40-V49 Car occupant injured in transport accident	0.632	0.368
M70 Soft tissue disorders related to use, overuse and pressure	0.631	0.369
R22.9 Localised swelling, mass and lump, unspecified	0.631	0.369
G94.1 Hydrocephalus in neoplastic disease	0.631	0.369
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.631	0.369
Y51 Drugs primarily affecting the autonomic nervous system	0.630	0.370
D37-D48 Neoplasms of uncertain or unknown behaviour	0.629	0.371
T31.0 Burns involving less than 10% of body surface	0.628	0.372
Chapter VIII Diseases of the ear and mastoid process	0.627	0.372
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.627	0.373
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.627	0.373
S19 Other and unspecified injuries of neck	0.627	0.373
B15-B19 Viral hepatitis	0.626	0.373
G95.9 Disease of spinal cord, unspecified	0.626	0.374
D35 Benign neoplasm of other and unspecified endocrine glands	0.626	0.374
B25 Cytomegaloviral disease	0.626	0.374
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere	0.626	0.374
E11.9 Without complications	0.626	0.374
R17 Unspecified jaundice	0.626	0.374
M41 Scoliosis	0.625	0.375
C01 Malignant neoplasm of base of tongue	0.625	0.375
Y35-Y36 Legal intervention and operations of war	0.623	0.377
Y10-Y34 Event of undetermined intent	0.623	0.377
Y00-Y09 Assault	0.623	0.377

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations