TreeWAS – Variant ID: rs12777

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Chapter II Neoplasms	1.000	0.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.999	0.001	0.000
D10-D36 Benign neoplasms	0.999	0.001	0.000
C15-C26 Malignant neoplasms of digestive organs	0.998	0.002	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.997	0.003	0.000
Chapter XX External causes of morbidity and mortality	0.996	0.004	0.000
C18 Malignant neoplasm of colon	0.996	0.004	0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.992	0.008	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.991	0.009	0.000
D12.3 Transverse colon	0.987	0.013	0.000
S60-S69 Injuries to the wrist and hand	0.986	0.014	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.985	0.015	0.000
D12.5 Sigmoid colon	0.984	0.016	0.000
C50-C50 Malignant neoplasm of breast	0.984	0.016	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.977	0.023	0.000
S61 Open wound of wrist and hand	0.977	0.023	0.000
C50 Malignant neoplasm of breast	0.973	0.027	0.000
C77.3 Axillary and upper limb lymph nodes	0.969	0.031	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.969	0.031	0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.968	0.032	0.000
S61.0 Open wound of finger(s) without damage to nail	0.968	0.032	0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.960	0.040	0.000
C18.7 Sigmoid colon	0.958	0.042	0.000
T43.2 Other and unspecified antidepressants	0.952	0.048	0.000
C77.2 Intra-abdominal lymph nodes	0.949	0.051	0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.948	0.052	0.000
C50.4 Upper-outer quadrant of breast	0.947	0.053	0.000
Y43 Primarily systemic agents	0.940	0.060	0.000
R93 Abnormal findings on diagnostic imaging of other body structures	0.940	0.060	0.000
W20-W49 Exposure to inanimate mechanical forces	0.938	0.062	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.932	0.068	0.000
C77.9 Lymph node, unspecified	0.931	0.069	0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.931	0.069	0.000
C50.9 Breast, unspecified	0.930	0.070	0.000
C18.0 Caecum	0.929	0.071	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.926	0.074	0.000
D32 Benign neoplasm of meninges	0.926	0.074	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.925	0.075	0.000
C51-C58 Malignant neoplasms of female genital organs	0.924	0.076	0.000
D12.8 Rectum	0.919	0.081	0.000
R79 Other abnormal findings of blood chemistry	0.916	0.084	0.000
R26 Abnormalities of gait and mobility	0.906	0.094	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.905	0.095	0.000
R79.8 Other specified abnormal findings of blood chemistry	0.899	0.101	0.000
Y43.3 Other antineoplastic drugs	0.897	0.103	0.000
D18 Haemangioma and lymphangioma, any site	0.892	0.108	0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract	0.890	0.110	0.000
C18.9 Colon, unspecified	0.880	0.120	0.000
R73 Elevated blood glucose level	0.877	0.123	0.000
S40-S49 Injuries to the shoulder and upper arm	0.874	0.126	0.000
R26.8 Other and unspecified abnormalities of gait and mobility	0.872	0.128	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.872	0.128	0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.870	0.130	0.000
C54 Malignant neoplasm of corpus uteri	0.868	0.132	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.865	0.135	0.000
Chapter VII Diseases of the eye and adnexa	0.863	0.137	0.000
T66-T78 Other and unspecified effects of external causes	0.853	0.147	0.000
D12.4 Descending colon	0.849	0.151	0.000
T91 Sequelae of injuries of neck and trunk	0.848	0.152	0.000
S70-S79 Injuries to the hip and thigh	0.847	0.153	0.000
H43-H45 Disorders of vitreous body and globe	0.847	0.153	0.000
D16 Benign neoplasm of bone and articular cartilage	0.845	0.155	0.000
D32.0 Cerebral meninges	0.842	0.158	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.838	0.162	0.000
H43 Disorders of vitreous body	0.837	0.163	0.000
W29 Contact with other powered hand tools and household machinery	0.837	0.163	0.000
R94 Abnormal results of function studies	0.836	0.164	0.000
D34 Benign neoplasm of thyroid gland	0.835	0.165	0.000
S80-S89 Injuries to the knee and lower leg	0.835	0.165	0.000
W00-W19 Falls	0.834	0.165	0.000
D12.2 Ascending colon	0.834	0.166	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.834	0.166	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.831	0.169	0.000
C54.1 Endometrium	0.829	0.171	0.000
S10-S19 Injuries to the neck	0.823	0.177	0.000
S50-S59 Injuries to the elbow and forearm	0.823	0.177	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.821	0.179	0.000
C78.7 Secondary malignant neoplasm of liver	0.821	0.179	0.000
Chapter I Certain infectious and parasitic diseases	0.821	0.179	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.820	0.180	0.000
V10-V19 Pedal cyclist injured in transport accident	0.813	0.187	0.000
C23 Malignant neoplasm of gallbladder	0.811	0.189	0.000
C18.5 Splenic flexure	0.811	0.189	0.000
T92 Sequelae of injuries of upper limb	0.810	0.190	0.000
W50-W64 Exposure to animate mechanical forces	0.807	0.193	0.000
C78.2 Secondary malignant neoplasm of pleura	0.807	0.193	0.000
C77.8 Lymph nodes of multiple regions	0.806	0.194	0.000
S61.9 Open wound of wrist and hand, part unspecified	0.801	0.199	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.800	0.200	0.000
C18.6 Descending colon	0.800	0.200	0.000
D33 Benign neoplasm of brain and other parts of central nervous system	0.799	0.201	0.000
C50.1 Central portion of breast	0.799	0.201	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.799	0.201	0.000
C53 Malignant neoplasm of cervix uteri	0.798	0.202	0.000
R73.9 Hyperglycaemia, unspecified	0.796	0.204	0.000
Y40 Systemic antibiotics	0.792	0.208	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.791	0.209	0.000
D18.0 Haemangioma, any site	0.786	0.214	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.784	0.216	0.000
D36 Benign neoplasm of other and unspecified sites	0.782	0.218	0.000
C24.1 Ampulla of Vater	0.782	0.218	0.000
H43.8 Other disorders of vitreous body	0.780	0.220	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.779	0.221	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.776	0.224	0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.774	0.226	0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.774	0.226	0.000
C77.4 Inguinal and lower limb lymph nodes	0.773	0.227	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.771	0.229	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.770	0.230	0.000
Chapter V Mental and behavioural disorders	0.770	0.230	0.000
C21 Malignant neoplasm of anus and anal canal	0.766	0.234	0.000
H43.1 Vitreous haemorrhage	0.766	0.234	0.000
D24 Benign neoplasm of breast	0.765	0.235	0.000
W29.9 Unspecified place	0.765	0.235	0.000
D32.9 Meninges, unspecified	0.762	0.238	0.000
W22 Striking against or struck by other objects	0.762	0.238	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.761	0.239	0.000
S61.7 Multiple open wounds of wrist and hand	0.758	0.242	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.757	0.243	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.756	0.243	0.000
Y43.1 Antineoplastic antimetabolites	0.756	0.244	0.000
S90-S99 Injuries to the ankle and foot	0.755	0.245	0.000
T91.8 Sequelae of other specified injuries of neck and trunk	0.754	0.246	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.753	0.247	0.000
R90 Abnormal findings on diagnostic imaging of central nervous system	0.753	0.247	0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system	0.750	0.250	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.747	0.253	0.000
R47-R49 Symptoms and signs involving speech and voice	0.746	0.254	0.000
Y45.0 Opioids and related analgesics	0.746	0.254	0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.745	0.255	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.743	0.257	0.000
Y52 Agents primarily affecting the cardiovascular system	0.743	0.257	0.000
S64 Injury of nerves at wrist and hand level	0.742	0.258	0.000
C18.3 Hepatic flexure	0.742	0.258	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.742	0.258	0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.742	0.258	0.000
D26 Other benign neoplasms of uterus	0.740	0.260	0.000
C18.4 Transverse colon	0.740	0.260	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.739	0.261	0.000
H43.3 Other vitreous opacities	0.736	0.264	0.000
D12.0 Caecum	0.736	0.264	0.000
W49 Exposure to other and unspecified inanimate mechanical forces	0.735	0.265	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.733	0.267	0.000
V40-V49 Car occupant injured in transport accident	0.732	0.268	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.730	0.270	0.000
D10 Benign neoplasm of mouth and pharynx	0.729	0.271	0.000
Y00-Y09 Assault	0.728	0.272	0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum	0.726	0.274	0.000
A00-A09 Intestinal infectious diseases	0.726	0.274	0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.724	0.276	0.000
R23 Other skin changes	0.723	0.277	0.000
Chapter XXII Codes for special purposes	0.722	0.278	0.000
R26.3 Immobility	0.722	0.278	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.719	0.281	0.000
R77 Other abnormalities of plasma proteins	0.719	0.281	0.000
R94.5 Abnormal results of liver function studies	0.718	0.282	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.717	0.283	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.717	0.283	0.000
T33-T35 Frostbite	0.717	0.283	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283	0.000
T00-T07 Injuries involving multiple body regions	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.717	0.283	0.000
D12.9 Anus and anal canal	0.716	0.284	0.000
D12.1 Appendix	0.716	0.284	0.000
D31 Benign neoplasm of eye and adnexa	0.716	0.284	0.000
D30 Benign neoplasm of urinary organs	0.716	0.284	0.000
D29 Benign neoplasm of male genital organs	0.716	0.284	0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.716	0.284	0.000
D19 Benign neoplasm of mesothelial tissue	0.716	0.284	0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.716	0.284	0.000
R27 Other lack of coordination	0.716	0.284	0.000
C17 Malignant neoplasm of small intestine	0.716	0.284	0.000
R21 Rash and other nonspecific skin eruption	0.715	0.285	0.000
C76 Malignant neoplasm of other and ill-defined sites	0.715	0.285	0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.714	0.286	0.000
Y35-Y36 Legal intervention and operations of war	0.714	0.286	0.000
Y10-Y34 Event of undetermined intent	0.714	0.286	0.000
X85-X99 Assault	0.714	0.286	0.000
X50-X57 Overexertion, travel and privation	0.714	0.286	0.000
X30-X39 Exposure to forces of nature	0.714	0.286	0.000
X10-X19 Contact with heat and hot substances	0.714	0.286	0.000
X00-X09 Exposure to smoke, fire and flames	0.714	0.286	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.714	0.286	0.000
W75-W84 Other accidental threats to breathing	0.714	0.286	0.000
W65-W74 Accidental drowning and submersion	0.714	0.286	0.000
V98-V99 Other and unspecified transport accidents	0.714	0.286	0.000
V95-V97 Air and space transport accidents	0.714	0.286	0.000
V90-V94 Water transport accidents	0.714	0.286	0.000
V70-V79 Bus occupant injured in transport accident	0.714	0.286	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.714	0.286	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.714	0.286	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.714	0.286	0.000
V01-V09 Pedestrian injured in transport accident	0.714	0.286	0.000
C18.8 Overlapping lesion of colon	0.714	0.286	0.000
W25 Contact with sharp glass	0.713	0.287	0.000
R25 Abnormal involuntary movements	0.713	0.287	0.000
V80-V89 Other land transport accidents	0.712	0.288	0.000
S43.0 Dislocation of shoulder joint	0.711	0.289	0.000
V20-V29 Motorcycle rider injured in transport accident	0.711	0.289	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.710	0.290	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.710	0.290	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.710	0.290	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.710	0.290	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.710	0.290	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.710	0.290	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.710	0.290	0.000
T36 Poisoning by systemic antibiotics	0.710	0.290	0.000
C53.9 Cervix uteri, unspecified	0.708	0.292	0.000
D18.1 Lymphangioma, any site	0.708	0.292	0.000
S81 Open wound of lower leg	0.708	0.292	0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures	0.707	0.293	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.707	0.293	0.000
S65 Injury of blood vessels at wrist and hand level	0.707	0.293	0.000
C78.4 Secondary malignant neoplasm of small intestine	0.706	0.294	0.000
R95-R99 Ill-defined and unknown causes of mortality	0.706	0.294	0.000
S50 Superficial injury of forearm	0.705	0.295	0.000
C81 Hodgkin's disease	0.704	0.296	0.000
S62 Fracture at wrist and hand level	0.703	0.297	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.703	0.297	0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity	0.702	0.298	0.000
C34 Malignant neoplasm of bronchus and lung	0.702	0.298	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.700	0.299	0.001
Y59 Other and unspecified vaccines and biological substances	0.701	0.299	0.000
Y58 Bacterial vaccines	0.701	0.299	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.701	0.299	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.701	0.299	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.701	0.299	0.000
Y48 Anaesthetics and therapeutic gases	0.701	0.299	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.701	0.299	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.701	0.299	0.000
T93 Sequelae of injuries of lower limb	0.701	0.299	0.000
X20-X29 Contact with venomous animals and plants	0.701	0.299	0.000
Y43.4 Immunosuppressive agents	0.700	0.300	0.000
S67 Crushing injury of wrist and hand	0.699	0.301	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.698	0.302	0.000
T91.1 Sequelae of fracture of spine	0.698	0.302	0.000
C50.6 Axillary tail of breast	0.697	0.303	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.696	0.304	0.000
X60-X84 Intentional self-harm	0.696	0.304	0.000
A04 Other bacterial intestinal infections	0.695	0.305	0.000
S80 Superficial injury of lower leg	0.695	0.305	0.000
T43.9 Psychotropic drug, unspecified	0.695	0.305	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.695	0.305	0.000
T43.6 Psychostimulants with abuse potential	0.695	0.305	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.695	0.305	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.695	0.305	0.000
W20 Struck by thrown, projected or falling object	0.695	0.305	0.000
R92 Abnormal findings on diagnostic imaging of breast	0.694	0.306	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.693	0.307	0.000
R71 Abnormality of red blood cells	0.693	0.307	0.000
R73.0 Abnormal glucose tolerance test	0.692	0.308	0.000
T92.1 Sequelae of fracture of arm	0.692	0.308	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.689	0.311	0.000
R78 Findings of drugs and other substances, not normally found in blood	0.689	0.311	0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]	0.689	0.311	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.688	0.312	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.688	0.312	0.000
C18.1 Appendix	0.687	0.313	0.000
H10-H13 Disorders of conjunctiva	0.686	0.314	0.000
S79 Other and unspecified injuries of hip and thigh	0.685	0.315	0.000
D16.4 Bones of skull and face	0.685	0.315	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.684	0.316	0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract	0.683	0.317	0.000
R82 Other abnormal findings in urine	0.683	0.317	0.000
V18 Pedal cyclist injured in noncollision transport accident	0.682	0.318	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.682	0.318	0.000
Q50-Q56 Congenital malformations of genital organs	0.681	0.319	0.000
R94.4 Abnormal results of kidney function studies	0.681	0.319	0.000
D16.3 Short bones of lower limb	0.680	0.319	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.680	0.320	0.000
T75 Effects of other external causes	0.678	0.322	0.000
T78 Adverse effects, not elsewhere classified	0.676	0.324	0.000
S72 Fracture of femur	0.675	0.325	0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.675	0.325	0.000
R72 Abnormality of white blood cells, not elsewhere classified	0.675	0.325	0.000
R74 Abnormal serum enzyme levels	0.674	0.326	0.000
C50.3 Lower-inner quadrant of breast	0.674	0.326	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.674	0.326	0.000
Y43.9 Primarily systemic agent, unspecified	0.674	0.326	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.674	0.326	0.000
Y43.6 Enzymes, not elsewhere classified	0.674	0.326	0.000
Y43.5 Acidifying and alkalising agents	0.674	0.326	0.000
Y43.2 Antineoplastic natural products	0.674	0.326	0.000
Y43.0 Antiallergic and antiemetic drugs	0.674	0.326	0.000
R93.6 Abnormal findings on diagnostic imaging of limbs	0.674	0.326	0.000
C55 Malignant neoplasm of uterus, part unspecified	0.673	0.327	0.000
R91 Abnormal findings on diagnostic imaging of lung	0.673	0.327	0.000
W46 Contact with hypodermic needle	0.672	0.327	0.000
W45 Foreign body or object entering through skin	0.672	0.327	0.000
W43 Exposure to vibration	0.672	0.327	0.000
W42 Exposure to noise	0.672	0.327	0.000
W41 Exposure to high-pressure jet	0.672	0.327	0.000
W40 Explosion of other materials	0.672	0.327	0.000
W39 Discharge of firework	0.672	0.327	0.000
W38 Explosion and rupture of other specified pressurised devices	0.672	0.327	0.000
W37 Explosion and rupture of pressurised tyre, pipe or hose	0.672	0.327	0.000
W36 Explosion and rupture of gas cylinder	0.672	0.327	0.000
W35 Explosion and rupture of boiler	0.672	0.327	0.000
W34 Discharge from other and unspecified firearms	0.672	0.327	0.000
W33 Rifle, shotgun and larger firearm discharge	0.672	0.327	0.000
W32 Handgun discharge	0.672	0.327	0.000
W31 Contact with other and unspecified machinery	0.672	0.327	0.000
W30 Contact with agricultural machinery	0.672	0.327	0.000
W28 Contact with powered lawn mower	0.672	0.327	0.000
W27 Contact with nonpowered hand tool	0.672	0.327	0.000
W26 Contact with knife, sword or dagger	0.672	0.327	0.000
W24 Contact with lifting and transmission devices, not elsewhere classified	0.672	0.327	0.000
W23 Caught, crushed, jammed or pinched in or between objects	0.672	0.327	0.000
W21 Striking against or struck by sports equipment	0.672	0.327	0.000
M86-M90 Other osteopathies	0.669	0.330	0.001
C92 Myeloid leukaemia	0.669	0.331	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.668	0.332	0.000
T39.4 Antirheumatics, not elsewhere classified	0.668	0.332	0.000
T39.2 Pyrazolone derivatives	0.668	0.332	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.668	0.332	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.668	0.332	0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.667	0.332	0.000
C78.1 Secondary malignant neoplasm of mediastinum	0.667	0.332	0.000
M80-M85 Disorders of bone density and structure	0.666	0.334	0.000
D21 Other benign neoplasms of connective and other soft tissue	0.665	0.335	0.000
T98 Sequelae of other and unspecified effects of external causes	0.664	0.336	0.000
T95 Sequelae of burns, corrosions and frostbite	0.664	0.336	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.664	0.336	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.664	0.336	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.664	0.336	0.000
S68 Traumatic amputation of wrist and hand	0.664	0.336	0.000
D32.1 Spinal meninges	0.664	0.336	0.000
D11 Benign neoplasm of major salivary glands	0.663	0.336	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.664	0.336	0.000
T92.2 Sequelae of fracture at wrist and hand level	0.663	0.337	0.000
C57 Malignant neoplasm of other and unspecified female genital organs	0.662	0.337	0.000
C58 Malignant neoplasm of placenta	0.662	0.337	0.000
C52 Malignant neoplasm of vagina	0.662	0.337	0.000
W44 Foreign body entering into or through eye or natural orifice	0.662	0.338	0.000
R79.0 Abnormal level of blood mineral	0.662	0.338	0.000
S61.1 Open wound of finger(s) with damage to nail	0.662	0.338	0.000
C79 Secondary malignant neoplasm of other sites	0.662	0.338	0.000
A04.8 Other specified bacterial intestinal infections	0.662	0.338	0.000
W07 Fall involving chair	0.661	0.339	0.000
D28 Benign neoplasm of other and unspecified female genital organs	0.661	0.339	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.660	0.340	0.000
S71 Open wound of hip and thigh	0.660	0.340	0.000
C26 Malignant neoplasm of other and ill-defined digestive organs	0.659	0.341	0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified	0.659	0.341	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.658	0.342	0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.657	0.343	0.000
Y54.3 Benzothiadiazine derivatives	0.657	0.343	0.000
A15-A19 Tuberculosis	0.657	0.343	0.000
D33.3 Cranial nerves	0.656	0.344	0.000
S14 Injury of nerves and spinal cord at neck level	0.656	0.344	0.000
R26.0 Ataxic gait	0.656	0.344	0.000
W08 Fall involving other furniture	0.656	0.344	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.654	0.345	0.000
T68 Hypothermia	0.653	0.347	0.000
S64.3 Injury of digital nerve of thumb	0.651	0.349	0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs	0.650	0.350	0.000
R29.6 Tendency to fall, not elsewhere classified	0.650	0.350	0.000
W55 Bitten or struck by other mammals	0.650	0.350	0.000
C18.2 Ascending colon	0.650	0.350	0.000
R26.1 Paralytic gait	0.649	0.350	0.000
C34.3 Lower lobe, bronchus or lung	0.648	0.352	0.000
Y40.8 Other systemic antibiotics	0.647	0.353	0.000
S81.0 Open wound of knee	0.647	0.353	0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.646	0.354	0.000
T79-T79 Certain early complications of trauma	0.646	0.354	0.000
C22.1 Intrahepatic bile duct carcinoma	0.645	0.355	0.000
S61.8 Open wound of other parts of wrist and hand	0.643	0.357	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.642	0.358	0.000
Chapter XXI Factors influencing health status and contact with health services	0.642	0.358	0.000
C50.5 Lower-outer quadrant of breast	0.641	0.359	0.000
D35 Benign neoplasm of other and unspecified endocrine glands	0.641	0.359	0.000
T14 Injury of unspecified body region	0.640	0.359	0.000
W18 Other fall on same level	0.640	0.360	0.000
A80-A89 Viral infections of the central nervous system	0.639	0.360	0.000
R23.8 Other and unspecified skin changes	0.639	0.361	0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.639	0.361	0.000
Chapter VIII Diseases of the ear and mastoid process	0.637	0.363	0.000
S80.8 Other superficial injuries of lower leg	0.637	0.363	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.637	0.363	0.000
Y40.3 Macrolides	0.636	0.364	0.000
R20 Disturbances of skin sensation	0.635	0.365	0.000
W22.9 Unspecified place	0.635	0.365	0.000
Y45.2 Propionic acid derivatives	0.635	0.365	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.633	0.367	0.000
H18 Other disorders of cornea	0.632	0.368	0.000
D14 Benign neoplasm of middle ear and respiratory system	0.632	0.368	0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.632	0.368	0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.632	0.368	0.000
T39.0 Salicylates	0.631	0.368	0.000
C50.0 Nipple and areola	0.630	0.370	0.000
B50-B64 Protozoal diseases	0.628	0.372	0.000
A04.7 Enterocolitis due to Clostridium difficile	0.627	0.373	0.000
C51 Malignant neoplasm of vulva	0.627	0.373	0.000
S48 Traumatic amputation of shoulder and upper arm	0.627	0.373	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.627	0.373	0.000
S44 Injury of nerves at shoulder and upper arm level	0.627	0.373	0.000
S41 Open wound of shoulder and upper arm	0.627	0.373	0.000
S47 Crushing injury of shoulder and upper arm	0.627	0.373	0.000
C24.9 Biliary tract, unspecified	0.625	0.375	0.000
C24.8 Overlapping lesion of biliary tract	0.625	0.375	0.000
C24.0 Extrahepatic bile duct	0.625	0.375	0.000
D36.1 Peripheral nerves and autonomic nervous system	0.625	0.375	0.000
M89 Other disorders of bone	0.624	0.376	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.624	0.376	0.000
H55-H59 Other disorders of eye and adnexa	0.624	0.376	0.000
C54.9 Corpus uteri, unspecified	0.623	0.377	0.000
C54.8 Overlapping lesion of corpus uteri	0.623	0.377	0.000
C54.3 Fundus uteri	0.623	0.377	0.000
C54.2 Myometrium	0.623	0.377	0.000
C54.0 Isthmus uteri	0.623	0.377	0.000
S56 Injury of muscle and tendon at forearm level	0.622	0.378	0.000
C91 Lymphoid leukaemia	0.622	0.378	0.000
Y49.5 Other antipsychotics and neuroleptics	0.621	0.379	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.620	0.380	0.000
Y45.8 Other analgesics and antipyretics	0.620	0.380	0.000
Y45.5 4-Aminophenol derivatives	0.620	0.380	0.000
Y45.4 Antirheumatics	0.620	0.380	0.000
S50.9 Superficial injury of forearm, unspecified	0.620	0.380	0.000
T91.3 Sequelae of injury of spinal cord	0.620	0.380	0.000
S69 Other and unspecified injuries of wrist and hand	0.620	0.380	0.000
W19 Unspecified fall	0.620	0.380	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.620	0.380	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.619	0.381	0.000
H52 Disorders of refraction and accommodation	0.617	0.383	0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.617	0.383	0.000
H40-H42 Glaucoma	0.616	0.384	0.000
Z45 Adjustment and management of implanted device	0.615	0.385	0.000
M84 Disorders of continuity of bone	0.614	0.385	0.000
Y57 Other and unspecified drugs and medicaments	0.614	0.386	0.000
C88 Malignant immunoproliferative diseases	0.613	0.387	0.000
Z40-Z54 Persons encountering health services for specific procedures and health care	0.612	0.388	0.000
T74 Maltreatment syndromes	0.611	0.388	0.000
T73 Effects of other deprivation	0.611	0.388	0.000
T70 Effects of air pressure and water pressure	0.611	0.388	0.000
T69 Other effects of reduced temperature	0.611	0.388	0.000
T67 Effects of heat and light	0.611	0.388	0.000
T71 Asphyxiation	0.611	0.388	0.000
T66 Unspecified effects of radiation	0.611	0.388	0.000
W50 Hit, struck, kicked, twisted, bitten or scratched by another person	0.611	0.389	0.000
C25 Malignant neoplasm of pancreas	0.611	0.389	0.000
Y45.1 Salicylates	0.610	0.389	0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.608	0.392	0.000
T91.9 Sequelae of unspecified injury of neck and trunk	0.608	0.392	0.000
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.608	0.392	0.000
T91.4 Sequelae of injury of intrathoracic organs	0.608	0.392	0.000
T91.2 Sequelae of other fracture of thorax and pelvis	0.608	0.392	0.000
T91.0 Sequelae of superficial injury and open wound of neck and trunk	0.608	0.392	0.000
C50.2 Upper-inner quadrant of breast	0.608	0.392	0.000
S78 Traumatic amputation of hip and thigh	0.607	0.392	0.000
S77 Crushing injury of hip and thigh	0.607	0.392	0.000
S76 Injury of muscle and tendon at hip and thigh level	0.607	0.392	0.000
S75 Injury of blood vessels at hip and thigh level	0.607	0.392	0.000
S74 Injury of nerves at hip and thigh level	0.607	0.392	0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.607	0.392	0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.607	0.393	0.000
S60 Superficial injury of wrist and hand	0.606	0.394	0.000
D16.9 Bone and articular cartilage, unspecified	0.606	0.394	0.000
D16.8 Pelvic bones, sacrum and coccyx	0.606	0.394	0.000
D16.7 Ribs, sternum and clavicle	0.606	0.394	0.000
D16.6 Vertebral column	0.606	0.394	0.000
D16.5 Lower jaw bone	0.606	0.394	0.000
D16.2 Long bones of lower limb	0.606	0.394	0.000
D16.1 Short bones of upper limb	0.606	0.394	0.000
D16.0 Scapula and long bones of upper limb	0.606	0.394	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.605	0.395	0.000
W13 Fall from, out of or through building or structure	0.604	0.395	0.000
S20-S29 Injuries to the thorax	0.604	0.396	0.000
T58 Toxic effect of carbon monoxide	0.603	0.396	0.000
W10 Fall on and from stairs and steps	0.603	0.397	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.602	0.398	0.000
S66.8 Injury of other muscles and tendons at wrist and hand level	0.601	0.399	0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.601	0.399	0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.601	0.399	0.000
H43.9 Disorder of vitreous body, unspecified	0.600	0.400	0.000
H43.2 Crystalline deposits in vitreous body	0.600	0.400	0.000
H43.0 Vitreous prolapse	0.600	0.400	0.000
W29.8 Other specified place	0.600	0.400	0.000
W29.6 Industrial and construction area	0.600	0.400	0.000
W29.0 Home	0.600	0.400	0.000
W29.7 Farm	0.600	0.400	0.000
W29.5 Trade and service area	0.600	0.400	0.000
W29.4 Street and highway	0.600	0.400	0.000
W29.3 Sports and athletics area	0.600	0.400	0.000
W29.2 School, other institution and public administrative area	0.600	0.400	0.000
W29.1 Residential institution	0.600	0.400	0.000
R94.8 Abnormal results of function studies of other organs and systems	0.600	0.400	0.000
R94.7 Abnormal results of other endocrine function studies	0.600	0.400	0.000
R94.6 Abnormal results of thyroid function studies	0.600	0.400	0.000
R94.2 Abnormal results of pulmonary function studies	0.600	0.400	0.000
R94.1 Abnormal results of function studies of peripheral nervous system and special senses	0.600	0.400	0.000
R94.0 Abnormal results of function studies of central nervous system	0.600	0.400	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.599	0.400	0.000
R49 Voice disturbances	0.599	0.401	0.000
C21.0 Anus, unspecified	0.599	0.401	0.000
D12.7 Rectosigmoid junction	0.598	0.401	0.000
S88 Traumatic amputation of lower leg	0.598	0.401	0.000
S87 Crushing injury of lower leg	0.598	0.401	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations