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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs75158997
log Bayes Factor = 16.3135
Chromosome 7   position 33,796,970  (GRCh37) Explore rs75158997 on Ensembl!
Variant rs75158997 is part of Cluster X0053

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
Chapter I Certain infectious and parasitic diseases
0.999 0.001 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.999 0.001 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.998 0.002 0.000
Chapter XX External causes of morbidity and mortality
0.997 0.003 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.997 0.003 0.000
S00-S09 Injuries to the head
0.995 0.005 0.000
Chapter VI Diseases of the nervous system
0.992 0.008 0.000
C15-C26 Malignant neoplasms of digestive organs
0.990 0.010 0.000
Chapter XXI Factors influencing health status and contact with health services
0.988 0.012 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.987 0.013 0.000
Z51 Other medical care
0.985 0.015 0.000
C78.2 Secondary malignant neoplasm of pleura
0.982 0.018 0.000
I51 Complications and ill-defined descriptions of heart disease
0.979 0.021 0.000
B95-B98 Bacterial, viral and other infectious agents
0.969 0.031 0.000
I34 Nonrheumatic mitral valve disorders
0.969 0.031 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.967 0.033 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.966 0.034 0.000
A30-A49 Other bacterial diseases
0.966 0.034 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.964 0.036 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.955 0.045 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.954 0.046 0.000
S06 Intracranial injury
0.954 0.046 0.000
S09 Other and unspecified injuries of head
0.953 0.047 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.952 0.048 0.000
Z45 Adjustment and management of implanted device
0.948 0.052 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.946 0.054 0.000
C78.0 Secondary malignant neoplasm of lung
0.945 0.055 0.000
Z51.1 Chemotherapy session for neoplasm
0.935 0.065 0.000
I34.0 Mitral (valve) insufficiency
0.935 0.065 0.000
R26 Abnormalities of gait and mobility
0.933 0.067 0.000
S50-S59 Injuries to the elbow and forearm
0.933 0.067 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.932 0.068 0.000
A41 Other septicaemia
0.930 0.070 0.000
I05-I09 Chronic rheumatic heart diseases
0.929 0.071 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.928 0.072 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.927 0.073 0.000
I51.9 Heart disease, unspecified
0.927 0.073 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.926 0.074 0.000
I51.8 Other ill-defined heart diseases
0.923 0.077 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.922 0.078 0.000
S60-S69 Injuries to the wrist and hand
0.920 0.080 0.000
S09.9 Unspecified injury of head
0.918 0.082 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.918 0.082 0.000
Y83.6 Removal of other organ (partial) (total)
0.916 0.084 0.000
R87 Abnormal findings in specimens from female genital organs
0.914 0.086 0.000
I47 Paroxysmal tachycardia
0.914 0.086 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.914 0.086 0.000
I45 Other conduction disorders
0.913 0.087 0.000
A00-A09 Intestinal infectious diseases
0.910 0.090 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.909 0.091 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.906 0.094 0.000
Z51.8 Other specified medical care
0.905 0.095 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.903 0.097 0.000
S51 Open wound of forearm
0.898 0.102 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.898 0.102 0.000
Y40 Systemic antibiotics
0.897 0.103 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.895 0.105 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.895 0.105 0.000
C18 Malignant neoplasm of colon
0.892 0.108 0.000
I42 Cardiomyopathy
0.889 0.111 0.000
Z40 Prophylactic surgery
0.886 0.114 0.000
G90-G99 Other disorders of the nervous system
0.886 0.114 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.884 0.116 0.000
Chapter XXII Codes for special purposes
0.884 0.116 0.000
Z51.5 Palliative care
0.883 0.117 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.883 0.117 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.883 0.117 0.000
Z45.2 Adjustment and management of vascular access device
0.879 0.121 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.879 0.121 0.000
S06.5 Traumatic subdural haemorrhage
0.872 0.128 0.000
I27 Other pulmonary heart diseases
0.870 0.130 0.000
D68 Other coagulation defects
0.869 0.131 0.000
Z51.3 Blood transfusion without reported diagnosis
0.865 0.135 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.865 0.135 0.000
C25 Malignant neoplasm of pancreas
0.860 0.140 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.857 0.143 0.000
Y44 Agents primarily affecting blood constituents
0.856 0.144 0.000
I47.1 Supraventricular tachycardia
0.855 0.145 0.000
D46 Myelodysplastic syndromes
0.855 0.145 0.000
C73 Malignant neoplasm of thyroid gland
0.852 0.148 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.851 0.149 0.000
C78.7 Secondary malignant neoplasm of liver
0.850 0.150 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.848 0.152 0.000
I50 Heart failure
0.848 0.152 0.000
R73 Elevated blood glucose level
0.845 0.155 0.000
R21 Rash and other nonspecific skin eruption
0.844 0.156 0.000
C80 Malignant neoplasm without specification of site
0.842 0.158 0.000
Q50-Q56 Congenital malformations of genital organs
0.841 0.159 0.000
R87.6 Abnormal cytological findings
0.841 0.159 0.000
Z54 Convalescence
0.840 0.160 0.000
C21 Malignant neoplasm of anus and anal canal
0.838 0.162 0.000
I31 Other diseases of pericardium
0.838 0.162 0.000
I46 Cardiac arrest
0.837 0.163 0.000
A04 Other bacterial intestinal infections
0.836 0.164 0.000
S62 Fracture at wrist and hand level
0.835 0.165 0.000
D69 Purpura and other haemorrhagic conditions
0.829 0.170 0.000
I05 Rheumatic mitral valve diseases
0.824 0.176 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.822 0.178 0.000
C45 Mesothelioma
0.822 0.178 0.000
G60 Hereditary and idiopathic neuropathy
0.821 0.179 0.000
C16 Malignant neoplasm of stomach
0.821 0.179 0.000
D45 Polycythaemia vera
0.820 0.180 0.000
G61 Inflammatory polyneuropathy
0.820 0.180 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.816 0.184 0.000
S05 Injury of eye and orbit
0.814 0.186 0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms
0.814 0.186 0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)
0.813 0.186 0.000
Y83.5 Amputation of limb(s)
0.813 0.187 0.000
G62 Other polyneuropathies
0.813 0.187 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.811 0.189 0.000
D75 Other diseases of blood and blood-forming organs
0.810 0.190 0.000
R12 Heartburn
0.809 0.191 0.000
W20-W49 Exposure to inanimate mechanical forces
0.808 0.192 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.808 0.192 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.808 0.192 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.807 0.193 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.806 0.194 0.000
G30-G32 Other degenerative diseases of the nervous system
0.805 0.195 0.000
S06.8 Other intracranial injuries
0.805 0.195 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.804 0.196 0.000
D46.9 Myelodysplastic syndrome, unspecified
0.804 0.196 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.803 0.197 0.000
I45.1 Other and unspecified right bundle-branch block
0.802 0.198 0.000
A40 Streptococcal septicaemia
0.801 0.199 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.800 0.200 0.000
I51.4 Myocarditis, unspecified
0.797 0.203 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.796 0.204 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.796 0.204 0.000
B15-B19 Viral hepatitis
0.796 0.204 0.000
W50-W64 Exposure to animate mechanical forces
0.795 0.205 0.000
V10-V19 Pedal cyclist injured in transport accident
0.795 0.205 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.794 0.206 0.000
S67 Crushing injury of wrist and hand
0.794 0.206 0.000
R73.9 Hyperglycaemia, unspecified
0.794 0.206 0.000
S01 Open wound of head
0.791 0.209 0.000
C18.2 Ascending colon
0.788 0.211 0.000
C18.0 Caecum
0.788 0.212 0.000
S10-S19 Injuries to the neck
0.787 0.212 0.000
Q60-Q64 Congenital malformations of the urinary system
0.787 0.213 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.787 0.213 0.000
R23 Other skin changes
0.786 0.214 0.000
Y44.2 Anticoagulants
0.785 0.215 0.000
G93 Other disorders of brain
0.785 0.215 0.000
Chapter V Mental and behavioural disorders
0.783 0.217 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.781 0.218 0.000
D68.9 Coagulation defect, unspecified
0.781 0.219 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.779 0.221 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.778 0.222 0.000
I31.9 Disease of pericardium, unspecified
0.777 0.223 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.777 0.223 0.000
I34.1 Mitral (valve) prolapse
0.777 0.223 0.000
B99-B99 Other infectious diseases
0.776 0.224 0.000
Z41 Procedures for purposes other than remedying health state
0.776 0.224 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.775 0.224 0.000
S90-S99 Injuries to the ankle and foot
0.775 0.225 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.775 0.225 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.774 0.226 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.774 0.226 0.000
I27.0 Primary pulmonary hypertension
0.772 0.228 0.000
A39 Meningococcal infection
0.771 0.229 0.000
A04.8 Other specified bacterial intestinal infections
0.770 0.230 0.000
S51.0 Open wound of elbow
0.770 0.230 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.769 0.231 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.769 0.231 0.000
Y40.9 Systemic antibiotic, unspecified
0.769 0.231 0.000
C97 Malignant neoplasms of independent (primary) multiple sites
0.767 0.232 0.000
Z51.0 Radiotherapy session
0.766 0.234 0.000
Y83.0 Surgical operation with transplant of whole organ
0.766 0.234 0.000
S51.8 Open wound of other parts of forearm
0.764 0.236 0.000
R87.7 Abnormal histological findings
0.764 0.236 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.764 0.236 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.763 0.237 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.763 0.237 0.000
T66-T78 Other and unspecified effects of external causes
0.762 0.238 0.000
X60-X84 Intentional self-harm
0.762 0.238 0.000
S51.9 Open wound of forearm, part unspecified
0.760 0.240 0.000
Q80-Q89 Other congenital malformations
0.759 0.241 0.000
D80-D89 Certain disorders involving the immune mechanism
0.759 0.241 0.000
Y40.3 Macrolides
0.758 0.242 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.757 0.242 0.000
S02 Fracture of skull and facial bones
0.757 0.243 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.757 0.243 0.000
R74 Abnormal serum enzyme levels
0.757 0.243 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.756 0.244 0.000
C80.9 Malignant neoplasm, unspecified
0.756 0.244 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.755 0.245 0.000
C15 Malignant neoplasm of oesophagus
0.754 0.245 0.000
I30 Acute pericarditis
0.753 0.247 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.753 0.247 0.000
C23 Malignant neoplasm of gallbladder
0.752 0.248 0.000
Z44 Fitting and adjustment of external prosthetic device
0.752 0.248 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.751 0.249 0.000
I42.2 Other hypertrophic cardiomyopathy
0.750 0.250 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.749 0.250 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.749 0.251 0.000
C17 Malignant neoplasm of small intestine
0.748 0.252 0.000
X50-X57 Overexertion, travel and privation
0.748 0.252 0.000
I46.0 Cardiac arrest with successful resuscitation
0.748 0.252 0.000
T93 Sequelae of injuries of lower limb
0.748 0.252 0.000
R87.9 Unspecified abnormal finding
0.748 0.252 0.000
I47.0 Reentry ventricular arrhythmia
0.748 0.252 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.747 0.252 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.747 0.253 0.000
I07 Rheumatic tricuspid valve diseases
0.747 0.253 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.746 0.253 0.000
I08 Multiple valve diseases
0.746 0.254 0.000
R45 Symptoms and signs involving emotional state
0.745 0.254 0.000
I45.4 Nonspecific intraventricular block
0.744 0.256 0.000
S62.6 Fracture of other finger
0.743 0.257 0.000
Q51 Congenital malformations of uterus and cervix
0.743 0.257 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.743 0.257 0.000
S06.3 Focal brain injury
0.742 0.258 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.741 0.259 0.000
E00-E07 Disorders of thyroid gland
0.741 0.259 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.740 0.260 0.000
R71 Abnormality of red blood cells
0.740 0.260 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.739 0.261 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.739 0.261 0.000
T91 Sequelae of injuries of neck and trunk
0.739 0.261 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.738 0.262 0.000
S06.9 Intracranial injury, unspecified
0.738 0.262 0.000
I37 Pulmonary valve disorders
0.737 0.263 0.000
I51.0 Cardiac septal defect, acquired
0.736 0.264 0.000
I50.9 Heart failure, unspecified
0.736 0.264 0.000
Z54.0 Convalescence following surgery
0.735 0.265 0.000
G70-G73 Diseases of myoneural junction and muscle
0.735 0.265 0.000
T79-T79 Certain early complications of trauma
0.735 0.265 0.000
C51-C58 Malignant neoplasms of female genital organs
0.734 0.266 0.000
Y40.0 Penicillins
0.733 0.267 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.733 0.267 0.000
D70 Agranulocytosis
0.733 0.267 0.000
R85 Abnormal findings in specimens from digestive organs and abdominal cavity
0.730 0.270 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.730 0.270 0.000
Y57 Other and unspecified drugs and medicaments
0.729 0.270 0.000
R17 Unspecified jaundice
0.728 0.272 0.000
Z46 Fitting and adjustment of other devices
0.727 0.273 0.000
Z45.1 Adjustment and management of infusion pump
0.727 0.273 0.000
A08 Viral and other specified intestinal infections
0.727 0.273 0.000
Y52 Agents primarily affecting the cardiovascular system
0.727 0.273 0.000
C45.9 Mesothelioma, unspecified
0.727 0.273 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.725 0.275 0.000
S51.7 Multiple open wounds of forearm
0.725 0.275 0.000
G91 Hydrocephalus
0.723 0.277 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.723 0.277 0.000
G40-G47 Episodic and paroxysmal disorders
0.723 0.277 0.000
R41.3 Other amnesia
0.722 0.278 0.000
Z43 Attention to artificial openings
0.721 0.279 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.721 0.279 0.000
Y84.0 Cardiac catheterisation
0.721 0.279 0.000
R25 Abnormal involuntary movements
0.721 0.279 0.000
D75.1 Secondary polycythaemia
0.721 0.279 0.000
X20-X29 Contact with venomous animals and plants
0.720 0.280 0.000
R26.3 Immobility
0.720 0.280 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.720 0.280 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.720 0.280 0.000
C50-C50 Malignant neoplasm of breast
0.720 0.280 0.000
I45.8 Other specified conduction disorders
0.719 0.281 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.719 0.281 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.718 0.282 0.000
D69.6 Thrombocytopenia, unspecified
0.718 0.282 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
S09.8 Other specified injuries of head
0.717 0.283 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.716 0.284 0.000
B65-B83 Helminthiases
0.716 0.284 0.000
B50-B64 Protozoal diseases
0.716 0.284 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.716 0.284 0.000
A75-A79 Rickettsioses
0.716 0.284 0.000
A70-A74 Other diseases caused by chlamydiae
0.716 0.284 0.000
A65-A69 Other spirochaetal diseases
0.716 0.284 0.000
A20-A28 Certain zoonotic bacterial diseases
0.716 0.284 0.000
A15-A19 Tuberculosis
0.716 0.284 0.000
Y42.7 Androgens and anabolic congeners
0.716 0.284 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.716 0.284 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.716 0.284 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.716 0.284 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.715 0.285 0.000
S64 Injury of nerves at wrist and hand level
0.715 0.285 0.000
Y35-Y36 Legal intervention and operations of war
0.715 0.285 0.000
Y10-Y34 Event of undetermined intent
0.715 0.285 0.000
Y00-Y09 Assault
0.715 0.285 0.000
X85-X99 Assault
0.715 0.285 0.000
X30-X39 Exposure to forces of nature
0.715 0.285 0.000
X10-X19 Contact with heat and hot substances
0.715 0.285 0.000
X00-X09 Exposure to smoke, fire and flames
0.715 0.285 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.715 0.285 0.000
W75-W84 Other accidental threats to breathing
0.715 0.285 0.000
W65-W74 Accidental drowning and submersion
0.715 0.285 0.000
V98-V99 Other and unspecified transport accidents
0.715 0.285 0.000
V95-V97 Air and space transport accidents
0.715 0.285 0.000
V90-V94 Water transport accidents
0.715 0.285 0.000
V70-V79 Bus occupant injured in transport accident
0.715 0.285 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.715 0.285 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.715 0.285 0.000
V40-V49 Car occupant injured in transport accident
0.715 0.285 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.715 0.285 0.000
V01-V09 Pedestrian injured in transport accident
0.715 0.285 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.715 0.285 0.000
I38 Endocarditis, valve unspecified
0.715 0.285 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.714 0.286 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.714 0.286 0.000
S08 Traumatic amputation of part of head
0.713 0.287 0.000
S07 Crushing injury of head
0.713 0.287 0.000
S04 Injury of cranial nerves
0.713 0.287 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.713 0.287 0.000
R26.2 Difficulty in walking, not elsewhere classified
0.712 0.288 0.000
S06.4 Epidural haemorrhage
0.712 0.288 0.000
C25.2 Tail of pancreas
0.711 0.289 0.000
C25.9 Pancreas, unspecified
0.711 0.289 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.710 0.290 0.000
C18.6 Descending colon
0.709 0.291 0.000
G62.9 Polyneuropathy, unspecified
0.709 0.291 0.000
T87 Complications peculiar to reattachment and amputation
0.709 0.291 0.000
Z49 Care involving dialysis
0.708 0.291 0.000
Q00-Q07 Congenital malformations of the nervous system
0.708 0.292 0.000
I36 Nonrheumatic tricuspid valve disorders
0.707 0.293 0.000
R47-R49 Symptoms and signs involving speech and voice
0.707 0.293 0.000
S62.5 Fracture of thumb
0.706 0.294 0.000
Z51.6 Desensitisation to allergens
0.706 0.294 0.000
I42.6 Alcoholic cardiomyopathy
0.705 0.294 0.000
I45.9 Conduction disorder, unspecified
0.705 0.295 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.704 0.296 0.000
S67.0 Crushing injury of thumb and other finger(s)
0.704 0.296 0.000
I51.6 Cardiovascular disease, unspecified
0.702 0.298 0.000
I51.5 Myocardial degeneration
0.702 0.298 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.702 0.298 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.702 0.298 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.702 0.298 0.000
S70-S79 Injuries to the hip and thigh
0.701 0.299 0.000
S06.2 Diffuse brain injury
0.701 0.299 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.700 0.300 0.000
B25-B34 Other viral diseases
0.699 0.300 0.000
G61.0 Guillain-Barre syndrome
0.699 0.301 0.000
S06.80 Other intracranial injuries (without open intracranial wound)
0.698 0.302 0.000
R23.8 Other and unspecified skin changes
0.697 0.303 0.000
I27.9 Pulmonary heart disease, unspecified
0.696 0.304 0.000
I05.1 Rheumatic mitral insufficiency
0.695 0.304 0.000
Z45.8 Adjustment and management of other implanted devices
0.695 0.305 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.695 0.305 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.695 0.305 0.000
R27 Other lack of coordination
0.694 0.306 0.000
S62.61 Fracture of other finger (open)
0.694 0.306 0.000
I27.2 Other secondary pulmonary hypertension
0.694 0.306 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.693 0.307 0.000
A48 Other bacterial diseases, not elsewhere classified
0.693 0.307 0.000
A44 Bartonellosis
0.693 0.307 0.000
A43 Nocardiosis
0.693 0.307 0.000
A42 Actinomycosis
0.693 0.307 0.000
A37 Whooping cough
0.693 0.307 0.000
A36 Diphtheria
0.693 0.307 0.000
A32 Listeriosis
0.693 0.307 0.000
A31 Infection due to other mycobacteria
0.693 0.307 0.000
A30 Leprosy [Hansen's disease]
0.693 0.307 0.000
A38 Scarlet fever
0.693 0.307 0.000
A35 Other tetanus
0.693 0.307 0.000
A34 Obstetrical tetanus
0.693 0.307 0.000
A33 Tetanus neonatorum
0.693 0.307 0.000
C21.1 Anal canal
0.692 0.308 0.000
I05.9 Mitral valve disease, unspecified
0.688 0.312 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.688 0.312 0.000
R43 Disturbances of smell and taste
0.687 0.313 0.000
R26.0 Ataxic gait
0.686 0.314 0.000
Z51.9 Medical care, unspecified
0.685 0.315 0.000
D68.8 Other specified coagulation defects
0.685 0.315 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.685 0.315 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.685 0.315 0.000
Q35-Q37 Cleft lip and cleft palate
0.685 0.315 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.685 0.315 0.000
Y59 Other and unspecified vaccines and biological substances
0.684 0.316 0.000
Y58 Bacterial vaccines
0.684 0.316 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.684 0.316 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.684 0.316 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.684 0.316 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.684 0.316 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.684 0.316 0.000
Y48 Anaesthetics and therapeutic gases
0.684 0.316 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.684 0.316 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.684 0.316 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.684 0.316 0.000
S06.7 Intracranial injury with prolonged coma
0.684 0.316 0.000
S06.1 Traumatic cerebral oedema
0.684 0.316 0.000
S09.7 Multiple injuries of head
0.683 0.317 0.000
S09.2 Traumatic rupture of ear drum
0.683 0.317 0.000
S09.1 Injury of muscle and tendon of head
0.683 0.317 0.000
S09.0 Injury of blood vessels of head, not elsewhere classified
0.683 0.317 0.000
G03 Meningitis due to other and unspecified causes
0.683 0.317 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.683 0.317 0.000
R89 Abnormal findings in specimens from other organs, systems and tissues
0.683 0.317 0.000
R84 Abnormal findings in specimens from respiratory organs and thorax
0.683 0.317 0.000
R83 Abnormal findings in cerebrospinal fluid
0.683 0.317 0.000
A40.3 Septicaemia due to Streptococcus pneumoniae
0.683 0.317 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.683 0.317 0.000
G93.3 Postviral fatigue syndrome
0.683 0.317 0.000
R86 Abnormal findings in specimens from male genital organs
0.682 0.318 0.000
I50.1 Left ventricular failure
0.682 0.318 0.000
E04 Other non-toxic goitre
0.681 0.318 0.000
D68.2 Hereditary deficiency of other clotting factors
0.681 0.319 0.000
G60.0 Hereditary motor and sensory neuropathy
0.680 0.320 0.000
V20-V29 Motorcycle rider injured in transport accident
0.680 0.320 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.680 0.320 0.000
Z45.9 Adjustment and management of unspecified implanted device
0.680 0.320 0.000
Z45.3 Adjustment and management of implanted hearing device
0.680 0.320 0.000
I44 Atrioventricular and left bundle-branch block
0.679 0.321 0.000
Q54 Hypospadias
0.679 0.321 0.000
G64 Other disorders of peripheral nervous system
0.678 0.322 0.000
I26 Pulmonary embolism
0.678 0.322 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.678 0.322 0.000
D55-D59 Haemolytic anaemias
0.677 0.323 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.677 0.323 0.000
A80-A89 Viral infections of the central nervous system
0.676 0.324 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.675 0.324 0.000
S20-S29 Injuries to the thorax
0.675 0.325 0.000
T90 Sequelae of injuries of head
0.675 0.325 0.000
R76 Other abnormal immunological findings in serum
0.675 0.325 0.000
D69.5 Secondary thrombocytopenia
0.674 0.326 0.000
G60.8 Other hereditary and idiopathic neuropathies
0.674 0.326 0.000
I27.8 Other specified pulmonary heart diseases
0.673 0.327 0.000
Y84.1 Kidney dialysis
0.673 0.327 0.000
Q51.3 Bicornate uterus
0.673 0.327 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.671 0.329 0.000
V80-V89 Other land transport accidents
0.670 0.329 0.000
A41.8 Other specified septicaemia
0.669 0.330 0.000
R26.1 Paralytic gait
0.669 0.331 0.000
G80 Infantile cerebral palsy
0.669 0.331 0.000
S59 Other and unspecified injuries of forearm
0.669 0.331 0.000
S58 Traumatic amputation of forearm
0.669 0.331 0.000
S57 Crushing injury of forearm
0.669 0.331 0.000
S56 Injury of muscle and tendon at forearm level
0.669 0.331 0.000
S55 Injury of blood vessels at forearm level
0.669 0.331 0.000
S54 Injury of nerves at forearm level
0.669 0.331 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.669 0.331 0.000
D67 Hereditary factor IX deficiency
0.668 0.331 0.000
D66 Hereditary factor VIII deficiency
0.668 0.331 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.668 0.331 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.668 0.332 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.668 0.332 0.000
C18.1 Appendix
0.668 0.332 0.000
A41.4 Septicaemia due to anaerobes
0.667 0.333 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.667 0.333 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.667 0.333 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.666 0.334 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.666 0.334 0.000
I09 Other rheumatic heart diseases
0.666 0.334 0.000
I06 Rheumatic aortic valve diseases
0.666 0.334 0.000
R94 Abnormal results of function studies
0.666 0.334 0.000
G90 Disorders of autonomic nervous system
0.666 0.334 0.000
X58 Exposure to other specified factors
0.666 0.334 0.000
G95 Other diseases of spinal cord
0.665 0.335 0.000
Y40.8 Other systemic antibiotics
0.665 0.335 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.665 0.335 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.665 0.335 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.665 0.335 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.665 0.335 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.664 0.336 0.000
D75.9 Disease of blood and blood-forming organs, unspecified
0.664 0.336 0.000
I28 Other diseases of pulmonary vessels
0.664 0.336 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.663 0.337 0.000
C21.0 Anus, unspecified
0.663 0.337 0.000
D68.6 Other Thrombophilia
0.662 0.338 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.661 0.339 0.000
R77 Other abnormalities of plasma proteins
0.661 0.339 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.661 0.339 0.000
Z72 Problems related to lifestyle
0.661 0.339 0.000
Z42 Follow-up care involving plastic surgery
0.661 0.339 0.000
C60-C63 Malignant neoplasms of male genital organs
0.661 0.339 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.661 0.339 0.000
S65 Injury of blood vessels at wrist and hand level
0.660 0.340 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.660 0.340 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.659 0.340 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.659 0.340 0.000
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system
0.658 0.342 0.000
C46 Kaposi's sarcoma
0.658 0.342 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.658 0.342 0.000
Z29 Need for other prophylactic measures
0.656 0.344 0.000
R87.8 Other abnormal findings
0.655 0.344 0.000
R87.5 Abnormal microbiological findings
0.655 0.344 0.000
R87.4 Abnormal immunological findings
0.655 0.344 0.000
R87.3 Abnormal level of substances chiefly nonmedicinal as to source
0.655 0.344 0.000
R87.2 Abnormal level of other drugs, medicaments and biological substances
0.655 0.344 0.000
R87.1 Abnormal level of hormones
0.655 0.344 0.000
R87.0 Abnormal level of enzymes
0.655 0.344 0.000
C75 Malignant neoplasm of other endocrine glands and related structures
0.655 0.345 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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