TreeWAS – Variant ID: rs62373900

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
Chapter VII Diseases of the eye and adnexa	1.000	0.000	0.000
M50-M54 Other dorsopathies	1.000	0.000	0.000
Chapter VI Diseases of the nervous system	1.000	0.000	0.000
Chapter XX External causes of morbidity and mortality	1.000	0.000	0.000
M45-M49 Spondylopathies	0.998	0.002	0.000
H40-H42 Glaucoma	0.998	0.002	0.000
H40 Glaucoma	0.997	0.003	0.000
M50 Cervical disk disorders	0.994	0.006	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.992	0.008	0.000
M54 Dorsalgia	0.990	0.010	0.000
M65-M68 Disorders of synovium and tendon	0.986	0.014	0.000
M50.1 Cervical disk disorder with radiculopathy	0.985	0.015	0.000
M48 Other spondylopathies	0.978	0.022	0.000
H40.2 Primary angle-closure glaucoma	0.971	0.029	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.969	0.031	0.000
M67 Other disorders of synovium and tendon	0.963	0.037	0.000
M54.9 Dorsalgia, unspecified	0.960	0.040	0.000
S20-S29 Injuries to the thorax	0.959	0.041	0.000
G40-G47 Episodic and paroxysmal disorders	0.959	0.041	0.000
M48.0 Spinal stenosis	0.958	0.042	0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.956	0.044	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.954	0.046	0.000
G40 Epilepsy	0.950	0.050	0.000
M45 Ankylosing spondylitis	0.939	0.061	0.000
H40.1 Primary open-angle glaucoma	0.938	0.062	0.000
M67.8 Other specified disorders of synovium and tendon	0.934	0.066	0.000
H25-H28 Disorders of lens	0.929	0.071	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.927	0.073	0.000
X60-X84 Intentional self-harm	0.922	0.078	0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.921	0.079	0.000
Y83.8 Other surgical procedures	0.919	0.081	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.919	0.081	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.919	0.081	0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.916	0.084	0.000
M54.3 Sciatica	0.915	0.085	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.914	0.086	0.000
Chapter V Mental and behavioural disorders	0.913	0.087	0.000
D50-D53 Nutritional anaemias	0.912	0.088	0.000
M54.99 Dorsalgia, unspecified (Site unspecified)	0.910	0.090	0.000
M47 Spondylosis	0.909	0.091	0.000
H40.0 Glaucoma suspect	0.908	0.092	0.000
G90-G99 Other disorders of the nervous system	0.907	0.093	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.907	0.093	0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.906	0.094	0.000
G55.2 Nerve root and plexus compressions in spondylosis	0.905	0.095	0.000
M48.02 Spinal stenosis (Cervical region)	0.903	0.097	0.000
H40.9 Glaucoma, unspecified	0.891	0.109	0.000
G20-G26 Extrapyramidal and movement disorders	0.889	0.111	0.000
Q50-Q56 Congenital malformations of genital organs	0.882	0.118	0.000
M54.39 Sciatica (Site unspecified)	0.880	0.120	0.000
D80-D89 Certain disorders involving the immune mechanism	0.879	0.121	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.878	0.122	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.877	0.123	0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.875	0.125	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.875	0.125	0.000
M48.06 Spinal stenosis (Lumbar region)	0.872	0.128	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.869	0.131	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.868	0.132	0.000
M86-M90 Other osteopathies	0.868	0.132	0.000
D50 Iron deficiency anaemia	0.868	0.132	0.000
M65 Synovitis and tenosynovitis	0.866	0.134	0.000
G55.3 Nerve root and plexus compressions in other dorsopathies	0.862	0.138	0.000
S10-S19 Injuries to the neck	0.861	0.139	0.000
H25 Senile cataract	0.860	0.140	0.000
D50.9 Iron deficiency anaemia, unspecified	0.859	0.141	0.000
G40.9 Epilepsy, unspecified	0.853	0.147	0.000
T91 Sequelae of injuries of neck and trunk	0.851	0.149	0.000
S90-S99 Injuries to the ankle and foot	0.851	0.149	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.851	0.149	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.850	0.150	0.000
D60-D64 Aplastic and other anaemias	0.850	0.150	0.000
V40-V49 Car occupant injured in transport accident	0.849	0.151	0.000
M50.0 Cervical disk disorder with myelopathy	0.844	0.156	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.839	0.161	0.000
H53-H54 Visual disturbances and blindness	0.838	0.162	0.000
G20 Parkinson's disease	0.837	0.163	0.000
F41 Other anxiety disorders	0.837	0.163	0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)	0.834	0.166	0.000
S22.0 Fracture of thoracic vertebra	0.833	0.167	0.000
M47.2 Other spondylosis with radiculopathy	0.831	0.169	0.000
G82 Paraplegia and tetraplegia	0.829	0.171	0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.828	0.171	0.000
F41.2 Mixed anxiety and depressive disorder	0.828	0.172	0.000
H25.9 Senile cataract, unspecified	0.822	0.178	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.818	0.182	0.000
M65.9 Synovitis and tenosynovitis, unspecified	0.817	0.183	0.000
T51 Toxic effect of alcohol	0.816	0.184	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.815	0.185	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.813	0.187	0.000
M67.1 Other contracture of tendon (sheath)	0.812	0.188	0.000
T58 Toxic effect of carbon monoxide	0.811	0.189	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.808	0.192	0.000
W00-W19 Falls	0.808	0.192	0.000
H30-H36 Disorders of choroid and retina	0.807	0.193	0.000
H47 Other disorders of optic [2nd] nerve and visual pathways	0.806	0.194	0.000
M54.4 Lumbago with sciatica	0.804	0.196	0.000
S27 Injury of other and unspecified intrathoracic organs	0.800	0.200	0.000
H36 Retinal disorders in diseases classified elsewhere	0.799	0.201	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.799	0.201	0.000
H36.0 Diabetic retinopathy	0.795	0.205	0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.793	0.207	0.000
V10-V19 Pedal cyclist injured in transport accident	0.790	0.210	0.000
M54.1 Radiculopathy	0.789	0.211	0.000
X67 Intentional self-poisoning by and exposure to other gases and vapours	0.789	0.211	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.787	0.213	0.000
Q60-Q64 Congenital malformations of the urinary system	0.785	0.215	0.000
M48.5 Collapsed vertebra, not elsewhere classified	0.785	0.215	0.000
T79-T79 Certain early complications of trauma	0.781	0.219	0.000
X50-X57 Overexertion, travel and privation	0.780	0.220	0.000
X68 Intentional self-poisoning by and exposure to pesticides	0.776	0.224	0.000
Chapter I Certain infectious and parasitic diseases	0.774	0.226	0.000
F20 Schizophrenia	0.773	0.227	0.000
M53 Other dorsopathies, not elsewhere classified	0.772	0.228	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.771	0.229	0.000
X20-X29 Contact with venomous animals and plants	0.771	0.229	0.000
M50.2 Other cervical disk displacement	0.768	0.232	0.000
M48.09 Spinal stenosis (Site unspecified)	0.767	0.233	0.000
M47.9 Spondylosis, unspecified	0.765	0.235	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.765	0.235	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.764	0.236	0.000
M60-M63 Disorders of muscles	0.763	0.237	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.762	0.238	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.761	0.239	0.000
V20-V29 Motorcycle rider injured in transport accident	0.761	0.239	0.000
Q54 Hypospadias	0.761	0.239	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.760	0.240	0.000
H02 Other disorders of eyelid	0.759	0.241	0.000
V80-V89 Other land transport accidents	0.758	0.242	0.000
M80-M85 Disorders of bone density and structure	0.756	0.244	0.000
S22.4 Multiple fractures of ribs	0.756	0.244	0.000
Q80-Q89 Other congenital malformations	0.755	0.245	0.000
G83 Other paralytic syndromes	0.754	0.246	0.000
M46 Other inflammatory spondylopathies	0.752	0.248	0.000
M40-M43 Deforming dorsopathies	0.751	0.249	0.000
H05 Disorders of orbit	0.750	0.250	0.000
S60-S69 Injuries to the wrist and hand	0.749	0.251	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.748	0.252	0.000
G91 Hydrocephalus	0.748	0.252	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.748	0.252	0.000
T90 Sequelae of injuries of head	0.748	0.252	0.000
F20.9 Schizophrenia, unspecified	0.747	0.253	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.747	0.253	0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere	0.747	0.253	0.000
S22.1 Multiple fractures of thoracic spine	0.747	0.253	0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.746	0.254	0.000
A30-A49 Other bacterial diseases	0.745	0.255	0.000
S22.5 Flail chest	0.745	0.255	0.000
S12 Fracture of neck	0.745	0.255	0.000
W50-W64 Exposure to animate mechanical forces	0.742	0.258	0.000
H40.8 Other glaucoma	0.741	0.259	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.740	0.260	0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.739	0.261	0.000
H53 Visual disturbances	0.738	0.262	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.737	0.262	0.000
M51 Other intervertebral disk disorders	0.737	0.263	0.000
D80 Immunodeficiency with predominantly antibody defects	0.736	0.264	0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.736	0.264	0.000
T17 Foreign body in respiratory tract	0.733	0.267	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.732	0.268	0.000
G99 Other disorders of nervous system in diseases classified elsewhere	0.732	0.268	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.731	0.269	0.000
G98 Other disorders of nervous system, not elsewhere classified	0.731	0.269	0.000
M91-M94 Chondropathies	0.731	0.269	0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified	0.729	0.271	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.728	0.272	0.000
G62 Other polyneuropathies	0.727	0.273	0.000
D55-D59 Haemolytic anaemias	0.727	0.273	0.000
Y57 Other and unspecified drugs and medicaments	0.726	0.274	0.000
H50 Other strabismus	0.726	0.274	0.000
D53 Other nutritional anaemias	0.725	0.275	0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.725	0.275	0.000
G44 Other headache syndromes	0.725	0.275	0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)	0.724	0.276	0.000
X59 Exposure to unspecified factor	0.723	0.277	0.000
T00-T07 Injuries involving multiple body regions	0.723	0.277	0.000
G94 Other disorders of brain in diseases classified elsewhere	0.723	0.277	0.000
H02.0 Entropion and trichiasis of eyelid	0.722	0.278	0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system	0.721	0.279	0.000
G82.2 Paraplegia, unspecified	0.720	0.280	0.000
M49 Spondylopathies in diseases classified elsewhere	0.717	0.282	0.000
G97.1 Other reaction to spinal and lumbar puncture	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
W20-W49 Exposure to inanimate mechanical forces	0.717	0.283	0.000
Y35-Y36 Legal intervention and operations of war	0.717	0.283	0.000
Y10-Y34 Event of undetermined intent	0.717	0.283	0.000
Y00-Y09 Assault	0.717	0.283	0.000
X85-X99 Assault	0.717	0.283	0.000
X30-X39 Exposure to forces of nature	0.717	0.283	0.000
X10-X19 Contact with heat and hot substances	0.717	0.283	0.000
X00-X09 Exposure to smoke, fire and flames	0.717	0.283	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.717	0.283	0.000
W75-W84 Other accidental threats to breathing	0.717	0.283	0.000
W65-W74 Accidental drowning and submersion	0.717	0.283	0.000
V98-V99 Other and unspecified transport accidents	0.717	0.283	0.000
V95-V97 Air and space transport accidents	0.717	0.283	0.000
V90-V94 Water transport accidents	0.717	0.283	0.000
V70-V79 Bus occupant injured in transport accident	0.717	0.283	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.717	0.283	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.717	0.283	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.717	0.283	0.000
V01-V09 Pedestrian injured in transport accident	0.717	0.283	0.000
H42 Glaucoma in diseases classified elsewhere	0.716	0.284	0.000
T51.9 Alcohol, unspecified	0.716	0.284	0.000
S50-S59 Injuries to the elbow and forearm	0.716	0.284	0.000
H40.6 Glaucoma secondary to drugs	0.715	0.285	0.000
H40.4 Glaucoma secondary to eye inflammation	0.715	0.285	0.000
H40.3 Glaucoma secondary to eye trauma	0.715	0.285	0.000
S92 Fracture of foot, except ankle	0.715	0.285	0.000
S27.2 Traumatic heamopneumothorax	0.714	0.286	0.000
T91.1 Sequelae of fracture of spine	0.714	0.286	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.714	0.286	0.000
D62 Acute posthaemorrhagic anaemia	0.714	0.286	0.000
M50.9 Cervical disk disorder, unspecified	0.712	0.288	0.000
M50.8 Other cervical disk disorders	0.712	0.288	0.000
D64 Other anaemias	0.712	0.288	0.000
Q51 Congenital malformations of uterus and cervix	0.712	0.288	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.712	0.288	0.000
T33-T35 Frostbite	0.711	0.288	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.711	0.288	0.000
H27 Other disorders of lens	0.711	0.289	0.000
Y83.9 Surgical procedure, unspecified	0.710	0.290	0.000
M54.8 Other dorsalgia	0.710	0.290	0.000
M54.0 Panniculitis affecting regions of neck and back	0.710	0.290	0.000
Y52 Agents primarily affecting the cardiovascular system	0.710	0.290	0.000
H04 Disorders of lachrymal system	0.709	0.291	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.709	0.291	0.000
F03 Unspecified dementia	0.707	0.293	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.707	0.293	0.000
G41 Status epilepticus	0.707	0.293	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.707	0.293	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.707	0.293	0.000
M00-M03 Infectious arthropathies	0.706	0.294	0.000
G82.4 Spastic tetraplegia	0.705	0.295	0.000
G59 Mononeuropathy in diseases classified elsewhere	0.705	0.295	0.000
S20 Superficial injury of thorax	0.703	0.297	0.000
M48.9 Spondylopathy, unspecified	0.701	0.298	0.000
M48.8 Other specified spondylopathies	0.701	0.298	0.000
M48.4 Fatigue fracture of vertebra	0.701	0.298	0.000
M48.3 Traumatic spondylopathy	0.701	0.298	0.000
M48.2 Kissing spine	0.701	0.298	0.000
M48.1 Ankylosing hyperostosis [Forestier]	0.701	0.298	0.000
M88 Paget's disease of bone [osteitis deformans]	0.701	0.299	0.000
Q61 Cystic kidney disease	0.700	0.300	0.000
H25.8 Other senile cataract	0.699	0.301	0.000
H26 Other cataract	0.698	0.302	0.000
F80-F89 Disorders of psychological development	0.698	0.302	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.697	0.303	0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.697	0.303	0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)	0.696	0.304	0.000
D84 Other immunodeficiencies	0.695	0.305	0.000
S22.3 Fracture of rib	0.694	0.306	0.000
H25.1 Senile nuclear cataract	0.694	0.306	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.692	0.307	0.000
T91.3 Sequelae of injury of spinal cord	0.692	0.308	0.000
M67.9 Disorder of synovium and tendon, unspecified	0.690	0.310	0.000
M67.4 Ganglion	0.690	0.310	0.000
M67.3 Transient synovitis	0.690	0.310	0.000
M67.2 Synovial hypertrophy, not elsewhere classified	0.690	0.310	0.000
M67.0 Short Achilles tendon (acquired)	0.690	0.310	0.000
V49 Car occupant injured in other and unspecified transport accidents	0.689	0.311	0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)	0.688	0.311	0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)	0.688	0.311	0.000
M54.92 Dorsalgia, unspecified (Cervical region)	0.688	0.311	0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)	0.688	0.311	0.000
Q00-Q07 Congenital malformations of the nervous system	0.687	0.312	0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.687	0.312	0.000
S26 Injury of heart	0.687	0.312	0.000
S25 Injury of blood vessels of thorax	0.687	0.312	0.000
S24 Injury of nerves and spinal cord at thorax level	0.687	0.312	0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.687	0.312	0.000
S21 Open wound of thorax	0.687	0.312	0.000
G46 Vascular syndromes of brain in cerebrovascular diseases	0.687	0.313	0.000
M66 Spontaneous rupture of synovium and tendon	0.687	0.313	0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.687	0.313	0.000
M48.05 Spinal stenosis (Thoracolumbar region)	0.687	0.313	0.000
M48.04 Spinal stenosis (Thoracic region)	0.687	0.313	0.000
M48.03 Spinal stenosis (Cervicothoracic region)	0.687	0.313	0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.687	0.313	0.000
V48 Car occupant injured in noncollision transport accident	0.686	0.314	0.000
W06 Fall involving bed	0.685	0.315	0.000
M86 Osteomyelitis	0.685	0.315	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.684	0.316	0.000
Q35-Q37 Cleft lip and cleft palate	0.684	0.316	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.684	0.316	0.000
Chapter XXII Codes for special purposes	0.683	0.316	0.000
M54.5 Low back pain	0.683	0.317	0.000
F60-F69 Disorders of adult personality and behaviour	0.681	0.319	0.000
G40.7 Petit mal, unspecified, without grand mal seizures	0.681	0.319	0.000
G40.5 Special epileptic syndromes	0.681	0.319	0.000
G40.4 Other generalised epilepsy and epileptic syndromes	0.681	0.319	0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.681	0.319	0.000
M54.6 Pain in thoracic spine	0.681	0.319	0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)	0.679	0.321	0.000
H01 Other inflammation of eyelid	0.679	0.321	0.000
H47.2 Optic atrophy	0.678	0.322	0.000
M48.07 Spinal stenosis (Lumbosacral region)	0.678	0.322	0.000
M65.8 Other synovitis and tenosynovitis	0.675	0.325	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.675	0.325	0.000
A41 Other septicaemia	0.675	0.325	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.673	0.327	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.673	0.327	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.673	0.327	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.673	0.327	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.673	0.327	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.673	0.327	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.673	0.327	0.000
X78 Intentional self-harm by sharp object	0.672	0.328	0.000
X68.9 Unspecified place	0.672	0.328	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.671	0.329	0.000
S90 Superficial injury of ankle and foot	0.671	0.329	0.000
T91.9 Sequelae of unspecified injury of neck and trunk	0.671	0.329	0.000
M54.46 Lumbago with sciatica (Lumbar region)	0.671	0.329	0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)	0.669	0.331	0.000
T90.9 Sequelae of unspecified injury of head	0.669	0.331	0.000
F45 Somatoform disorders	0.668	0.332	0.000
H47.0 Disorders of optic nerve, not elsewhere classified	0.667	0.333	0.000
D52 Folate deficiency anaemia	0.667	0.333	0.000
S14 Injury of nerves and spinal cord at neck level	0.667	0.333	0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.667	0.333	0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere	0.666	0.334	0.000
G00 Bacterial meningitis, not elsewhere classified	0.666	0.334	0.000
F43 Reaction to severe stress, and adjustment disorders	0.666	0.334	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.665	0.335	0.000
G52 Disorders of other cranial nerves	0.665	0.335	0.000
Y83.4 Other reconstructive surgery	0.664	0.336	0.000
H53.0 Amblyopia ex anopsia	0.663	0.337	0.000
X84 Intentional self-harm by unspecified means	0.661	0.339	0.000
X83 Intentional self-harm by other specified means	0.661	0.339	0.000
X82 Intentional self-harm by crashing of motor vehicle	0.661	0.339	0.000
X81 Intentional self-harm by jumping or lying before moving object	0.661	0.339	0.000
X80 Intentional self-harm by jumping from a high place	0.661	0.339	0.000
X79 Intentional self-harm by blunt object	0.661	0.339	0.000
X77 Intentional self-harm by steam, hot vapours and hot objects	0.661	0.339	0.000
X76 Intentional self-harm by smoke, fire and flames	0.661	0.339	0.000
X75 Intentional self-harm by explosive material	0.661	0.339	0.000
X74 Intentional self-harm by other and unspecified firearm discharge	0.661	0.339	0.000
X73 Intentional self-harm by rifle, shotgun and larger firearm discharge	0.661	0.339	0.000
X72 Intentional self-harm by handgun discharge	0.661	0.339	0.000
X71 Intentional self-harm by drowning and submersion	0.661	0.339	0.000
X70 Intentional self-harm by hanging, strangulation and suffocation	0.661	0.339	0.000
X69 Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances	0.661	0.339	0.000
X66 Intentional self-poisoning by and exposure to organic solvents and halogenated hydrocarbons and their vapours	0.661	0.339	0.000
X65 Intentional self-poisoning by and exposure to alcohol	0.661	0.339	0.000
X64 Intentional self-poisoning by and exposure to other and unspecified drugs, medicaments and biological substances	0.661	0.339	0.000
X61 Intentional self-poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified	0.661	0.339	0.000
X60 Intentional self-poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics	0.661	0.339	0.000
T92 Sequelae of injuries of upper limb	0.659	0.340	0.000
S22.9 Fracture of bony thorax, part unspecified	0.659	0.341	0.000
S22.8 Fracture of other parts of bony thorax	0.659	0.341	0.000
T98 Sequelae of other and unspecified effects of external causes	0.659	0.341	0.000
T95 Sequelae of burns, corrosions and frostbite	0.659	0.341	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.659	0.341	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.659	0.341	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.659	0.341	0.000
S29 Other and unspecified injuries of thorax	0.659	0.341	0.000
T91.2 Sequelae of other fracture of thorax and pelvis	0.658	0.342	0.000
Y44 Agents primarily affecting blood constituents	0.657	0.343	0.000
X67.0 Home	0.656	0.344	0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.656	0.344	0.000
M54.35 Sciatica (Thoracolumbar region)	0.656	0.344	0.000
M54.34 Sciatica-Thoracic	0.656	0.344	0.000
M54.33 Sciatica-Cervicothoracic	0.656	0.344	0.000
M54.32 Sciatica-Cervical	0.656	0.344	0.000
M54.31 Sciatica-Occipit-atl-axl	0.656	0.344	0.000
M54.30 Sciatica (Multiple sites in spine)	0.656	0.344	0.000
T65 Toxic effect of other and unspecified substances	0.655	0.345	0.000
T62 Toxic effect of other noxious substances eaten as food	0.655	0.345	0.000
T61 Toxic effect of noxious substances eaten as seafood	0.655	0.345	0.000
T60 Toxic effect of pesticides	0.655	0.345	0.000
T57 Toxic effect of other inorganic substances	0.655	0.345	0.000
T56 Toxic effect of metals	0.655	0.345	0.000
T54 Toxic effect of corrosive substances	0.655	0.345	0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.655	0.345	0.000
T52 Toxic effect of organic solvents	0.655	0.345	0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.655	0.345	0.000
T55 Toxic effect of soaps and detergents	0.655	0.345	0.000
G96 Other disorders of central nervous system	0.655	0.345	0.000
M87 Osteonecrosis	0.655	0.345	0.000
M80 Osteoporosis with pathological fracture	0.655	0.345	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.655	0.345	0.000
F70-F79 Mental retardation	0.655	0.345	0.000
T51.0 Ethanol	0.654	0.346	0.000
G80 Infantile cerebral palsy	0.654	0.346	0.000
H02.6 Xanthelasma of eyelid	0.654	0.346	0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.653	0.347	0.000
M50.3 Other cervical disk degeneration	0.653	0.347	0.000
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.653	0.347	0.000
G45 Transient cerebral ischaemic attacks and related syndromes	0.653	0.347	0.000
M47.0 Anterior spinal and vertebral artery compression syndromes	0.652	0.348	0.000
G90 Disorders of autonomic nervous system	0.652	0.348	0.000
X41.9 Unspecified place	0.651	0.349	0.000
G92 Toxic encephalopathy	0.650	0.349	0.000
X58 Exposure to other specified factors	0.650	0.349	0.000
M90 Osteopathies in diseases classified elsewhere	0.650	0.350	0.000
M54.12 Radiculopathy (Cervical region)	0.650	0.350	0.000
Y84.6 Urinary catheterisation	0.649	0.351	0.000
H49 Paralytic strabismus	0.649	0.351	0.000
G50 Disorders of trigeminal nerve	0.649	0.351	0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders	0.648	0.352	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.647	0.353	0.000
S91 Open wound of ankle and foot	0.645	0.354	0.000
Y84.0 Cardiac catheterisation	0.645	0.355	0.000
Y48 Anaesthetics and therapeutic gases	0.645	0.355	0.000
M48.00 Spinal stenosis (Multiple sites in spine)	0.644	0.356	0.000
S19 Other and unspecified injuries of neck	0.643	0.357	0.000
G99.2 Myelopathy in diseases classified elsewhere	0.643	0.357	0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.643	0.357	0.000
X47 Accidental poisoning by and exposure to other gases and vapours	0.643	0.357	0.000
W08 Fall involving other furniture	0.642	0.358	0.000
S12.7 Multiple fractures of cervical spine	0.642	0.358	0.000
T18 Foreign body in alimentary tract	0.641	0.359	0.000
S70-S79 Injuries to the hip and thigh	0.640	0.359	0.000
G70-G73 Diseases of myoneural junction and muscle	0.640	0.360	0.000
S68 Traumatic amputation of wrist and hand	0.640	0.360	0.000
S22.40 Multiple fractures of ribs (closed)	0.638	0.362	0.000
G53 Cranial nerve disorders in diseases classified elsewhere	0.638	0.362	0.000
T91.8 Sequelae of other specified injuries of neck and trunk	0.638	0.362	0.000
G23 Other degenerative diseases of basal ganglia	0.637	0.363	0.000
G21 Secondary Parkinsonism	0.637	0.363	0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.637	0.363	0.000
G22 Parkinsonism in diseases classified elsewhere	0.637	0.363	0.000
M47.1 Other spondylosis with myelopathy	0.635	0.365	0.000
Y83.5 Amputation of limb(s)	0.634	0.365	0.000
M54.94 Dorsalgia, unspecified (Thoracic region)	0.634	0.366	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.634	0.366	0.000
Q54.9 Hypospadias, unspecified	0.633	0.366	0.000
A49 Bacterial infection of unspecified site	0.633	0.367	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.633	0.367	0.000
Q55 Other congenital malformations of male genital organs	0.633	0.367	0.000
Q53 Undescended testicle	0.633	0.367	0.000
Q52 Other congenital malformations of female genitalia	0.633	0.367	0.000
V18 Pedal cyclist injured in noncollision transport accident	0.632	0.367	0.000
H47.1 Papilloedema, unspecified	0.632	0.368	0.000
H05.0 Acute inflammation of orbit	0.631	0.369	0.000
S64 Injury of nerves at wrist and hand level	0.631	0.369	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.631	0.369	0.000
T11 Other injuries of upper limb, level unspecified	0.630	0.370	0.000
D83 Common variable immunodeficiency	0.630	0.370	0.000
D82 Immunodeficiency associated with other major defects	0.630	0.370	0.000
D81 Combined immunodeficiencies	0.630	0.370	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.630	0.370	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.630	0.370	0.000
H03 Disorders of eyelid in diseases classified elsewhere	0.630	0.370	0.000
X67.9 Unspecified place	0.629	0.371	0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere	0.628	0.371	0.000
H02.1 Ectropion of eyelid	0.628	0.372	0.000
M89 Other disorders of bone	0.628	0.372	0.000
W17 Other fall from one level to another	0.627	0.373	0.000
H50.1 Divergent concomitant strabismus	0.627	0.373	0.000
G82.5 Tetraplegia, unspecified	0.627	0.373	0.000
G95 Other diseases of spinal cord	0.627	0.373	0.000
B15-B19 Viral hepatitis	0.627	0.373	0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)	0.626	0.374	0.000
G30-G32 Other degenerative diseases of the nervous system	0.624	0.375	0.001
Y57.5 X-ray contrast media	0.624	0.376	0.000
G62.9 Polyneuropathy, unspecified	0.624	0.376	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.624	0.376	0.000
M54.17 Radiculopathy (Lumbosacral region)	0.624	0.376	0.000
Y59 Other and unspecified vaccines and biological substances	0.623	0.377	0.000
Y58 Bacterial vaccines	0.623	0.377	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.623	0.377	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.623	0.377	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.623	0.377	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.623	0.377	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.623	0.377	0.000
S22.10 Multiple fractures of thoracic spine (closed)	0.623	0.377	0.000
X50 Overexertion and strenuous or repetitive movements	0.623	0.377	0.000
F48 Other neurotic disorders	0.623	0.377	0.000
F44 Dissociative [conversion] disorders	0.623	0.377	0.000
G40.8 Other epilepsy	0.622	0.377	0.000
D50.1 Sideropenic dysphagia	0.622	0.378	0.000
H43-H45 Disorders of vitreous body and globe	0.621	0.378	0.000
M65.2 Calcific tendinitis	0.621	0.379	0.000
M65.1 Other infective (teno)synovitis	0.621	0.379	0.000
M65.0 Abscess of tendon sheath	0.621	0.379	0.000
G04 Encephalitis, myelitis and encephalomyelitis	0.621	0.379	0.000
G62.8 Other specified polyneuropathies	0.621	0.379	0.000
F20.0 Paranoid schizophrenia	0.620	0.380	0.000
S22.50 Flail chest (closed)	0.620	0.380	0.000
W01 Fall on same level from slipping, tripping and stumbling	0.619	0.381	0.000
W05 Fall involving wheelchair	0.619	0.381	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.617	0.382	0.000
S17 Crushing injury of neck	0.617	0.383	0.000
S15 Injury of blood vessels at neck level	0.617	0.383	0.000
S11 Open wound of neck	0.617	0.383	0.000
S18 Traumatic amputation at neck level	0.617	0.383	0.000
S16 Injury of muscle and tendon at neck level	0.617	0.383	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.617	0.383	0.000
H25.2 Senile cataract, morgagnian type	0.617	0.383	0.000
T66-T78 Other and unspecified effects of external causes	0.616	0.384	0.000
G83.1 Monoplegia of lower limb	0.616	0.384	0.000
G54 Nerve root and plexus disorders	0.615	0.385	0.000
M54.59 Low back pain (Site unspecified)	0.614	0.386	0.000
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)	0.614	0.386	0.000
Y40 Systemic antibiotics	0.614	0.386	0.000
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.613	0.387	0.000
M54.37 Sciatica (Lumbosacral region)	0.613	0.387	0.000
W03 Other fall on same level due to collision with, or pushing by, another person	0.613	0.387	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations