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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs74203920
log Bayes Factor = 13.9618
Chromosome 21   position 45,714,294  (GRCh37) Explore rs74203920 on Ensembl!
Variant rs74203920 is part of Cluster X0154

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
Chapter VIII Diseases of the ear and mastoid process
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter II Neoplasms
0.999 0.001 0.000
H90-H95 Other disorders of ear
0.994 0.006 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.994 0.006 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.991 0.009 0.000
D00-D09 In situ neoplasms
0.984 0.016 0.000
O60-O75 Complications of labour and delivery
0.982 0.018 0.000
Chapter XIV Diseases of the genitourinary system
0.979 0.021 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.978 0.022 0.000
H65-H75 Diseases of middle ear and mastoid
0.972 0.028 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.965 0.035 0.000
Chapter V Mental and behavioural disorders
0.964 0.036 0.000
W00-W19 Falls
0.963 0.037 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.955 0.045 0.000
C51-C58 Malignant neoplasms of female genital organs
0.951 0.049 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.948 0.052 0.000
H91 Other hearing loss
0.947 0.053 0.000
H90 Conductive and sensorineural hearing loss
0.944 0.056 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.941 0.059 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.941 0.059 0.000
T81 Complications of procedures, not elsewhere classified
0.935 0.065 0.000
N73 Other female pelvic inflammatory diseases
0.933 0.067 0.000
W19 Unspecified fall
0.931 0.069 0.000
D10-D36 Benign neoplasms
0.925 0.075 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.924 0.076 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.924 0.076 0.000
Y83.6 Removal of other organ (partial) (total)
0.923 0.077 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.922 0.078 0.000
H91.9 Hearing loss, unspecified
0.913 0.087 0.000
W19.9 Unspecified place
0.912 0.088 0.000
D05 Carcinoma in situ of breast
0.912 0.088 0.000
Chapter VII Diseases of the eye and adnexa
0.912 0.088 0.000
D25 Leiomyoma of uterus
0.911 0.089 0.000
N30-N39 Other diseases of urinary system
0.911 0.089 0.000
N73.6 Female pelvic peritoneal adhesions
0.910 0.090 0.000
M05-M14 Inflammatory polyarthropathies
0.910 0.090 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.906 0.094 0.000
Chapter XI Diseases of the digestive system
0.905 0.095 0.000
K55-K64 Other diseases of intestines
0.902 0.098 0.000
D25.0 Submucous leiomyoma of uterus
0.900 0.100 0.000
N39 Other disorders of urinary system
0.899 0.101 0.000
K62 Other diseases of anus and rectum
0.896 0.104 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.895 0.105 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.894 0.106 0.000
T66-T78 Other and unspecified effects of external causes
0.892 0.108 0.000
H90.5 Sensorineural hearing loss, unspecified
0.892 0.108 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.886 0.114 0.000
O70 Perineal laceration during delivery
0.886 0.114 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.886 0.114 0.000
M06 Other rheumatoid arthritis
0.883 0.117 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.882 0.118 0.000
S60-S69 Injuries to the wrist and hand
0.878 0.122 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.870 0.130 0.000
Y86 Sequelae of other accidents
0.869 0.131 0.000
Chapter IX Diseases of the circulatory system
0.869 0.131 0.000
K62.1 Rectal polyp
0.869 0.131 0.000
H80-H83 Diseases of inner ear
0.868 0.132 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.867 0.133 0.000
Y83.3 Surgical operation with formation of external stoma
0.862 0.138 0.000
H92 Otalgia and effusion of ear
0.861 0.139 0.000
H66 Suppurative and unspecified otitis media
0.861 0.139 0.000
M06.9 Rheumatoid arthritis, unspecified
0.857 0.143 0.000
O70.0 First degree perineal laceration during delivery
0.852 0.148 0.000
K63 Other diseases of intestine
0.850 0.150 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.848 0.152 0.000
C54 Malignant neoplasm of corpus uteri
0.848 0.152 0.000
N00-N08 Glomerular diseases
0.847 0.153 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.847 0.153 0.000
Chapter XXII Codes for special purposes
0.844 0.156 0.000
Chapter X Diseases of the respiratory system
0.843 0.157 0.000
H65 Nonsuppurative otitis media
0.842 0.158 0.000
C64-C68 Malignant neoplasms of urinary tract
0.840 0.160 0.000
D04 Carcinoma in situ of skin
0.835 0.165 0.000
N39.3 Stress incontinence
0.832 0.168 0.000
F30-F39 Mood [affective] disorders
0.831 0.169 0.000
D13.1 Stomach
0.825 0.175 0.000
S20-S29 Injuries to the thorax
0.824 0.176 0.000
K62.8 Other specified diseases of anus and rectum
0.816 0.184 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.810 0.190 0.000
N39.9 Disorder of urinary system, unspecified
0.807 0.193 0.000
F99-F99 Unspecified mental disorder
0.806 0.194 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.804 0.196 0.000
H72 Perforation of tympanic membrane
0.801 0.199 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.801 0.199 0.000
K63.8 Other specified diseases of intestine
0.800 0.200 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.800 0.200 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.799 0.201 0.000
D24 Benign neoplasm of breast
0.798 0.202 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.795 0.205 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.793 0.207 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.791 0.209 0.000
S90-S99 Injuries to the ankle and foot
0.790 0.210 0.000
K70-K77 Diseases of liver
0.789 0.211 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.789 0.211 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.788 0.212 0.000
N20-N23 Urolithiasis
0.785 0.215 0.000
T93 Sequelae of injuries of lower limb
0.785 0.215 0.000
N10-N16 Renal tubulo-interstitial diseases
0.785 0.215 0.000
T78 Adverse effects, not elsewhere classified
0.785 0.215 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.783 0.217 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.781 0.219 0.000
O36 Maternal care for other known or suspected foetal problems
0.780 0.220 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.780 0.220 0.000
C79 Secondary malignant neoplasm of other sites
0.779 0.221 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.779 0.221 0.000
D03 Melanoma in situ
0.777 0.223 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.777 0.223 0.000
Y95 Nosocomial condition
0.777 0.223 0.000
C54.1 Endometrium
0.774 0.226 0.000
Y88 Sequelae of surgical and medical care as external cause
0.772 0.228 0.000
N39.4 Other specified urinary incontinence
0.770 0.230 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.768 0.232 0.000
H73 Other disorders of tympanic membrane
0.767 0.233 0.000
D06 Carcinoma in situ of cervix uteri
0.767 0.233 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.767 0.233 0.000
M20-M25 Other joint disorders
0.766 0.234 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.765 0.235 0.000
F60-F69 Disorders of adult personality and behaviour
0.764 0.236 0.000
M10 Gout
0.761 0.239 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.760 0.240 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.760 0.240 0.000
O41 Other disorders of amniotic fluid and membranes
0.759 0.241 0.000
H74 Other disorders of middle ear and mastoid
0.757 0.243 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.755 0.245 0.000
Y85 Sequelae of transport accidents
0.753 0.247 0.000
I05-I09 Chronic rheumatic heart diseases
0.753 0.247 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.753 0.247 0.000
S80-S89 Injuries to the knee and lower leg
0.752 0.248 0.000
M80-M85 Disorders of bone density and structure
0.751 0.249 0.000
K61 Abscess of anal and rectal regions
0.751 0.249 0.000
H30-H36 Disorders of choroid and retina
0.750 0.250 0.000
D07.5 Prostate
0.749 0.251 0.000
N73.9 Female pelvic inflammatory disease, unspecified
0.749 0.251 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.749 0.251 0.000
M45-M49 Spondylopathies
0.748 0.252 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.748 0.252 0.000
S40-S49 Injuries to the shoulder and upper arm
0.747 0.253 0.000
C53 Malignant neoplasm of cervix uteri
0.744 0.256 0.000
O44 Placenta praevia
0.743 0.257 0.000
C56 Malignant neoplasm of ovary
0.742 0.258 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.741 0.258 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.741 0.258 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.741 0.259 0.000
N76 Other inflammation of vagina and vulva
0.739 0.261 0.000
O48 Prolonged pregnancy
0.739 0.261 0.000
J90-J94 Other diseases of pleura
0.738 0.262 0.000
S61 Open wound of wrist and hand
0.738 0.262 0.000
H92.0 Otalgia
0.737 0.263 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.736 0.264 0.000
M86-M90 Other osteopathies
0.736 0.264 0.000
D45 Polycythaemia vera
0.736 0.264 0.000
F80-F89 Disorders of psychological development
0.736 0.264 0.000
N39.8 Other specified disorders of urinary system
0.735 0.265 0.000
Chapter I Certain infectious and parasitic diseases
0.735 0.265 0.000
J60-J70 Lung diseases due to external agents
0.734 0.266 0.000
H66.9 Otitis media, unspecified
0.734 0.266 0.000
H81 Disorders of vestibular function
0.733 0.267 0.000
T79-T79 Certain early complications of trauma
0.732 0.268 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.732 0.268 0.000
D25.2 Subserosal leiomyoma of uterus
0.730 0.270 0.000
F32 Depressive episode
0.728 0.272 0.000
J95-J99 Other diseases of the respiratory system
0.726 0.274 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.726 0.274 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.726 0.274 0.000
H93 Other disorders of ear, not elsewhere classified
0.724 0.276 0.000
H90.2 Conductive hearing loss, unspecified
0.723 0.277 0.000
W20-W49 Exposure to inanimate mechanical forces
0.723 0.277 0.000
N30 Cystitis
0.721 0.279 0.000
H65.3 Chronic mucoid otitis media
0.721 0.279 0.000
H90.3 Sensorineural hearing loss, bilateral
0.720 0.280 0.000
Chapter XXI Factors influencing health status and contact with health services
0.719 0.281 0.000
K63.2 Fistula of intestine
0.719 0.281 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.718 0.282 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.717 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.717 0.283 0.000
Y10-Y34 Event of undetermined intent
0.717 0.283 0.000
Y00-Y09 Assault
0.717 0.283 0.000
X85-X99 Assault
0.717 0.283 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.717 0.283 0.000
X50-X57 Overexertion, travel and privation
0.717 0.283 0.000
X30-X39 Exposure to forces of nature
0.717 0.283 0.000
X20-X29 Contact with venomous animals and plants
0.717 0.283 0.000
X10-X19 Contact with heat and hot substances
0.717 0.283 0.000
X00-X09 Exposure to smoke, fire and flames
0.717 0.283 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.717 0.283 0.000
W75-W84 Other accidental threats to breathing
0.717 0.283 0.000
W65-W74 Accidental drowning and submersion
0.717 0.283 0.000
W50-W64 Exposure to animate mechanical forces
0.717 0.283 0.000
V98-V99 Other and unspecified transport accidents
0.717 0.283 0.000
V95-V97 Air and space transport accidents
0.717 0.283 0.000
V90-V94 Water transport accidents
0.717 0.283 0.000
V80-V89 Other land transport accidents
0.717 0.283 0.000
V70-V79 Bus occupant injured in transport accident
0.717 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.717 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.717 0.283 0.000
V40-V49 Car occupant injured in transport accident
0.717 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.717 0.283 0.000
V01-V09 Pedestrian injured in transport accident
0.717 0.283 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.716 0.284 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.284 0.000
W10 Fall on and from stairs and steps
0.716 0.284 0.000
Y40 Systemic antibiotics
0.716 0.284 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.715 0.285 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.714 0.286 0.000
V20-V29 Motorcycle rider injured in transport accident
0.713 0.286 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.713 0.287 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.713 0.287 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.713 0.287 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.713 0.287 0.000
O85-O92 Complications predominantly related to the puerperium
0.712 0.287 0.000
C67 Malignant neoplasm of bladder
0.712 0.288 0.000
T68 Hypothermia
0.712 0.288 0.000
S70-S79 Injuries to the hip and thigh
0.711 0.288 0.000
N99-N99 Other disorders of the genitourinary system
0.711 0.289 0.000
T87 Complications peculiar to reattachment and amputation
0.710 0.290 0.000
T86 Failure and rejection of transplanted organs and tissues
0.710 0.290 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.710 0.290 0.000
N60-N64 Disorders of breast
0.710 0.290 0.000
W07 Fall involving chair
0.709 0.291 0.000
H66.3 Other chronic suppurative otitis media
0.708 0.292 0.000
O62 Abnormalities of forces of labour
0.708 0.292 0.000
T78.3 Angioneurotic oedema
0.708 0.292 0.000
H80 Otosclerosis
0.707 0.292 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.707 0.293 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.707 0.293 0.000
N23 Unspecified renal colic
0.707 0.293 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.707 0.293 0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified
0.707 0.293 0.000
I10-I15 Hypertensive diseases
0.707 0.293 0.000
H33 Retinal detachments and breaks
0.707 0.293 0.000
N71 Inflammatory disease of uterus, except cervix
0.706 0.294 0.000
H60-H62 Diseases of external ear
0.706 0.294 0.000
O63 Long labour
0.706 0.294 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.706 0.294 0.000
D09 Carcinoma in situ of other and unspecified sites
0.705 0.295 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.705 0.295 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.705 0.295 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.705 0.295 0.000
K62.5 Haemorrhage of anus and rectum
0.705 0.295 0.000
Y83.9 Surgical procedure, unspecified
0.705 0.295 0.000
D47.2 Monoclonal gammopathy
0.704 0.296 0.000
O74 Complications of anaesthesia during labour and delivery
0.704 0.296 0.000
O73 Retained placenta and membranes, without haemorrhage
0.704 0.296 0.000
O71 Other obstetric trauma
0.704 0.296 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.704 0.296 0.000
O66 Other obstructed labour
0.704 0.296 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.704 0.296 0.000
O61 Failed induction of labour
0.704 0.296 0.000
O60 Preterm delivery
0.704 0.296 0.000
T90 Sequelae of injuries of head
0.704 0.296 0.000
Y52 Agents primarily affecting the cardiovascular system
0.700 0.300 0.000
K70 Alcoholic liver disease
0.700 0.300 0.000
Y42.5 Other oestrogens and progestogens
0.700 0.300 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.700 0.300 0.000
K62.0 Anal polyp
0.700 0.300 0.000
X60-X84 Intentional self-harm
0.699 0.301 0.000
O72 Postpartum haemorrhage
0.699 0.301 0.000
M23 Internal derangement of knee
0.698 0.302 0.000
N13 Obstructive and reflux uropathy
0.698 0.302 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.697 0.303 0.000
H70 Mastoiditis and related conditions
0.697 0.303 0.000
H69 Other disorders of Eustachian tube
0.697 0.303 0.000
H68 Eustachian salpingitis and obstruction
0.697 0.303 0.000
H67 Otitis media in diseases classified elsewhere
0.697 0.303 0.000
K65-K67 Diseases of peritoneum
0.696 0.304 0.000
M06.0 Seronegative rheumatoid arthritis
0.695 0.305 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.694 0.306 0.000
F99 Mental disorder, not otherwise specified
0.693 0.307 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.693 0.307 0.000
S64 Injury of nerves at wrist and hand level
0.693 0.307 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.692 0.308 0.000
L60-L75 Disorders of skin appendages
0.692 0.308 0.000
Y83.5 Amputation of limb(s)
0.692 0.308 0.000
Y83.0 Surgical operation with transplant of whole organ
0.692 0.308 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.692 0.308 0.000
Y83.4 Other reconstructive surgery
0.692 0.308 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.691 0.309 0.000
F70-F79 Mental retardation
0.691 0.309 0.000
W18 Other fall on same level
0.690 0.310 0.000
W17 Other fall from one level to another
0.690 0.310 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.690 0.310 0.000
W15 Fall from cliff
0.690 0.310 0.000
W14 Fall from tree
0.690 0.310 0.000
W13 Fall from, out of or through building or structure
0.690 0.310 0.000
W12 Fall on and from scaffolding
0.690 0.310 0.000
W11 Fall on and from ladder
0.690 0.310 0.000
W09 Fall involving playground equipment
0.690 0.310 0.000
W08 Fall involving other furniture
0.690 0.310 0.000
W06 Fall involving bed
0.690 0.310 0.000
W05 Fall involving wheelchair
0.690 0.310 0.000
W04 Fall while being carried or supported by other persons
0.690 0.310 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.690 0.310 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.690 0.310 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.690 0.310 0.000
W00 Fall on same level involving ice and snow
0.690 0.310 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.690 0.310 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.689 0.311 0.000
H25-H28 Disorders of lens
0.687 0.313 0.000
M91-M94 Chondropathies
0.687 0.313 0.000
H71 Cholesteatoma of middle ear
0.686 0.314 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.685 0.315 0.000
H40-H42 Glaucoma
0.685 0.315 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.683 0.317 0.000
I26 Pulmonary embolism
0.683 0.317 0.000
N04 Nephrotic syndrome
0.682 0.318 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.682 0.318 0.000
C51 Malignant neoplasm of vulva
0.682 0.318 0.000
C58 Malignant neoplasm of placenta
0.682 0.318 0.000
C52 Malignant neoplasm of vagina
0.682 0.318 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.682 0.318 0.000
H55-H59 Other disorders of eye and adnexa
0.682 0.318 0.000
N72 Inflammatory disease of cervix uteri
0.682 0.318 0.000
D04.5 Skin of trunk
0.681 0.319 0.000
H10-H13 Disorders of conjunctiva
0.680 0.320 0.000
Y89 Sequelae of other external causes
0.679 0.320 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.679 0.320 0.000
H91.8 Other specified hearing loss
0.679 0.321 0.000
H91.3 Deaf mutism, not elsewhere classified
0.679 0.321 0.000
H91.2 Sudden idiopathic hearing loss
0.679 0.321 0.000
H91.1 Presbycusis
0.679 0.321 0.000
H91.0 Ototoxic hearing loss
0.679 0.321 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.679 0.321 0.000
V10-V19 Pedal cyclist injured in transport accident
0.678 0.322 0.000
O42 Premature rupture of membranes
0.677 0.323 0.000
K62.6 Ulcer of anus and rectum
0.677 0.323 0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified
0.677 0.323 0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.677 0.323 0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral
0.677 0.323 0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.677 0.323 0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
0.677 0.323 0.000
H90.0 Conductive hearing loss, bilateral
0.677 0.323 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.677 0.323 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.677 0.323 0.000
Z37 Outcome of delivery
0.676 0.324 0.000
H33.3 Retinal breaks without detachment
0.676 0.324 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.676 0.324 0.000
K62.9 Disease of anus and rectum, unspecified
0.675 0.325 0.000
D10 Benign neoplasm of mouth and pharynx
0.675 0.325 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.674 0.325 0.000
M60-M63 Disorders of muscles
0.674 0.325 0.000
M00-M03 Infectious arthropathies
0.674 0.325 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.674 0.326 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.674 0.326 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.674 0.326 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.674 0.326 0.000
H92.1 Otorrhoea
0.674 0.326 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.673 0.327 0.000
D04.7 Skin of lower limb, including hip
0.672 0.328 0.000
T81.9 Unspecified complication of procedure
0.670 0.329 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.670 0.329 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.670 0.329 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.670 0.329 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.670 0.329 0.000
F03 Unspecified dementia
0.670 0.330 0.000
S62 Fracture at wrist and hand level
0.670 0.330 0.000
M40-M43 Deforming dorsopathies
0.669 0.331 0.000
Y44 Agents primarily affecting blood constituents
0.669 0.331 0.000
I27 Other pulmonary heart diseases
0.669 0.331 0.000
Z37.0 Single live birth
0.669 0.331 0.000
N73.8 Other specified female pelvic inflammatory diseases
0.669 0.331 0.000
N73.5 Female pelvic peritonitis, unspecified
0.669 0.331 0.000
N73.4 Female chronic pelvic peritonitis
0.669 0.331 0.000
N73.3 Female acute pelvic peritonitis
0.669 0.331 0.000
N73.2 Unspecified parametritis and pelvic cellulitis
0.669 0.331 0.000
N73.1 Chronic parametritis and pelvic cellulitis
0.669 0.331 0.000
N73.0 Acute parametritis and pelvic cellulitis
0.669 0.331 0.000
W19.8 Other specified place
0.668 0.332 0.000
W19.5 Trade and service area
0.668 0.332 0.000
W19.0 Home
0.668 0.332 0.000
W19.7 Farm
0.668 0.332 0.000
W19.6 Industrial and construction area
0.668 0.332 0.000
W19.3 Sports and athletics area
0.668 0.332 0.000
W19.1 Residential institution
0.668 0.332 0.000
N36 Other disorders of urethra
0.667 0.332 0.000
N05 Unspecified nephritic syndrome
0.667 0.333 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.667 0.333 0.000
N75 Diseases of Bartholin's gland
0.666 0.334 0.000
B95-B98 Bacterial, viral and other infectious agents
0.666 0.334 0.000
M70-M79 Other soft tissue disorders
0.666 0.334 0.000
M05 Seropositive rheumatoid arthritis
0.665 0.334 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.664 0.336 0.000
S00-S09 Injuries to the head
0.664 0.336 0.000
T92 Sequelae of injuries of upper limb
0.663 0.337 0.000
N02 Recurrent and persistent haematuria
0.663 0.337 0.000
D31 Benign neoplasm of eye and adnexa
0.663 0.337 0.000
D30 Benign neoplasm of urinary organs
0.663 0.337 0.000
D29 Benign neoplasm of male genital organs
0.663 0.337 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.663 0.337 0.000
D26 Other benign neoplasms of uterus
0.663 0.337 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.663 0.337 0.000
D19 Benign neoplasm of mesothelial tissue
0.663 0.337 0.000
D16 Benign neoplasm of bone and articular cartilage
0.663 0.337 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.663 0.337 0.000
D34 Benign neoplasm of thyroid gland
0.663 0.337 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.663 0.337 0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress
0.662 0.337 0.000
O45 Premature separation of placenta [abruptio placentae]
0.662 0.338 0.000
O43 Placental disorders
0.662 0.338 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.662 0.338 0.000
O33 Maternal care for known or suspected disproportion
0.662 0.338 0.000
O31 Complications specific to multiple gestation
0.662 0.338 0.000
O40 Polyhydramnios
0.662 0.338 0.000
N17-N19 Renal failure
0.661 0.339 0.000
K35-K38 Diseases of appendix
0.660 0.339 0.000
O30 Multiple gestation
0.660 0.340 0.000
I12 Hypertensive renal disease
0.660 0.340 0.000
S67 Crushing injury of wrist and hand
0.660 0.340 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.660 0.340 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.659 0.341 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.659 0.341 0.000
C97 Malignant neoplasms of independent (primary) multiple sites
0.659 0.341 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.658 0.342 0.000
K63.1 Perforation of intestine (nontraumatic)
0.658 0.342 0.000
D36 Benign neoplasm of other and unspecified sites
0.658 0.342 0.000
H65.9 Nonsuppurative otitis media, unspecified
0.658 0.342 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.657 0.343 0.000
M07 Psoriatic and enteropathic arthropathies
0.656 0.344 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.656 0.344 0.000
O00-O08 Pregnancy with abortive outcome
0.655 0.345 0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head
0.655 0.345 0.000
K62.3 Rectal prolapse
0.654 0.346 0.000
M10.9 Gout, unspecified
0.654 0.346 0.000
O36.5 Maternal care for poor foetal growth
0.654 0.346 0.000
D05.7 Other carcinoma in situ of breast
0.654 0.346 0.000
D05.0 Lobular carcinoma in situ
0.654 0.346 0.000
I08 Multiple valve diseases
0.654 0.346 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.654 0.346 0.000
N37 Urethral disorders in diseases classified elsewhere
0.653 0.347 0.000
N34 Urethritis and urethral syndrome
0.653 0.347 0.000
N33 Bladder disorders in diseases classified elsewhere
0.653 0.347 0.000
M14 Arthropathies in other diseases classified elsewhere
0.652 0.347 0.000
M12 Other specific arthropathies
0.652 0.347 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.652 0.347 0.000
M08 Juvenile arthritis
0.652 0.347 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.652 0.348 0.000
M45 Ankylosing spondylitis
0.652 0.348 0.000
W19.2 School, other institution and public administrative area
0.650 0.350 0.000
Y59 Other and unspecified vaccines and biological substances
0.650 0.350 0.000
Y58 Bacterial vaccines
0.650 0.350 0.000
Y57 Other and unspecified drugs and medicaments
0.650 0.350 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.650 0.350 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.650 0.350 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.650 0.350 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.650 0.350 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.650 0.350 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.650 0.350 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.650 0.350 0.000
Y48 Anaesthetics and therapeutic gases
0.650 0.350 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.650 0.350 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.650 0.350 0.000
N70 Salpingitis and oophoritis
0.649 0.350 0.000
J98 Other respiratory disorders
0.649 0.351 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.647 0.353 0.000
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure
0.646 0.354 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.646 0.354 0.000
I84 Haemorrhoids
0.645 0.355 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.644 0.356 0.000
N39.2 Orthostatic proteinuria, unspecified
0.644 0.356 0.000
N39.1 Persistent proteinuria, unspecified
0.644 0.356 0.000
S50-S59 Injuries to the elbow and forearm
0.644 0.356 0.000
H02 Other disorders of eyelid
0.644 0.356 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.643 0.357 0.000
K55 Vascular disorders of intestine
0.643 0.357 0.000
K62.2 Anal prolapse
0.642 0.357 0.000
D03.5 Melanoma in situ of trunk
0.642 0.358 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.642 0.358 0.000
W19.4 Street and highway
0.642 0.358 0.000
J69 Pneumonitis due to solids and liquids
0.642 0.358 0.000
F32.9 Depressive episode, unspecified
0.642 0.358 0.000
T98 Sequelae of other and unspecified effects of external causes
0.641 0.359 0.000
T95 Sequelae of burns, corrosions and frostbite
0.641 0.359 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.641 0.359 0.000
T91 Sequelae of injuries of neck and trunk
0.641 0.359 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.641 0.359 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.641 0.359 0.000
O41.0 Oligohydramnios
0.641 0.359 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.640 0.360 0.000
S92 Fracture of foot, except ankle
0.640 0.360 0.000
J90 Pleural effusion, not elsewhere classified
0.640 0.360 0.000
T75 Effects of other external causes
0.640 0.360 0.000
T74 Maltreatment syndromes
0.640 0.360 0.000
T73 Effects of other deprivation
0.640 0.360 0.000
T70 Effects of air pressure and water pressure
0.640 0.360 0.000
T69 Other effects of reduced temperature
0.640 0.360 0.000
T67 Effects of heat and light
0.640 0.360 0.000
T71 Asphyxiation
0.640 0.360 0.000
T66 Unspecified effects of radiation
0.640 0.360 0.000
H72.0 Central perforation of tympanic membrane
0.639 0.361 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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