TreeWAS – Variant ID: rs16918683

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
# Top node	1.000	0.000	0.000
Chapter XIV Diseases of the genitourinary system	1.000	0.000	0.000
N17-N19 Renal failure	0.999	0.001	0.000
Chapter XX External causes of morbidity and mortality	0.999	0.001	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.998	0.002	0.000
Chapter VIII Diseases of the ear and mastoid process	0.997	0.003	0.000
H80-H83 Diseases of inner ear	0.996	0.004	0.000
Chapter I Certain infectious and parasitic diseases	0.996	0.004	0.000
H81 Disorders of vestibular function	0.986	0.014	0.000
N18 Chronic renal failure	0.984	0.016	0.000
B95-B98 Bacterial, viral and other infectious agents	0.984	0.016	0.000
N19 Unspecified renal failure	0.983	0.017	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.983	0.017	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.981	0.019	0.000
N18.9 Chronic renal failure, unspecified	0.973	0.027	0.000
H83 Other diseases of inner ear	0.972	0.028	0.000
Y95 Nosocomial condition	0.972	0.028	0.000
Chapter XXI Factors influencing health status and contact with health services	0.971	0.029	0.000
Z40-Z54 Persons encountering health services for specific procedures and health care	0.970	0.030	0.000
Z45.0 Adjustment and management of cardiac pacemaker	0.968	0.032	0.000
Z45 Adjustment and management of implanted device	0.968	0.032	0.000
S40-S49 Injuries to the shoulder and upper arm	0.962	0.038	0.000
H81.0 Meniere's disease	0.960	0.040	0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.957	0.043	0.000
H83.0 Labyrinthitis	0.955	0.045	0.000
Z50 Care involving use of rehabilitation procedures	0.953	0.047	0.000
N10-N16 Renal tubulo-interstitial diseases	0.950	0.050	0.000
N00-N08 Glomerular diseases	0.947	0.053	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.942	0.058	0.000
N17 Acute renal failure	0.938	0.062	0.000
S10-S19 Injuries to the neck	0.936	0.064	0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.935	0.065	0.000
H81.1 Benign paroxysmal vertigo	0.933	0.067	0.000
S42 Fracture of shoulder and upper arm	0.932	0.068	0.000
Z50.2 Alcohol rehabilitation	0.930	0.070	0.000
A00-A09 Intestinal infectious diseases	0.930	0.070	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.922	0.078	0.000
N25-N29 Other disorders of kidney and ureter	0.918	0.082	0.000
D50-D53 Nutritional anaemias	0.914	0.086	0.000
N02 Recurrent and persistent haematuria	0.909	0.091	0.000
Chapter II Neoplasms	0.907	0.093	0.000
D50 Iron deficiency anaemia	0.906	0.094	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.902	0.098	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.901	0.099	0.000
A04 Other bacterial intestinal infections	0.901	0.099	0.000
Chapter XXII Codes for special purposes	0.899	0.101	0.000
S42.0 Fracture of clavicle	0.897	0.103	0.000
N17.9 Acute renal failure, unspecified	0.896	0.104	0.000
Y57 Other and unspecified drugs and medicaments	0.894	0.106	0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.893	0.107	0.000
N10 Acute tubulo-interstitial nephritis	0.892	0.108	0.000
B97 Viral agents as the cause of diseases classified to other chapters	0.887	0.113	0.000
H60-H62 Diseases of external ear	0.885	0.115	0.000
N02.9 Unspecified	0.884	0.116	0.000
A04.7 Enterocolitis due to Clostridium difficile	0.877	0.123	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.875	0.125	0.000
S70-S79 Injuries to the hip and thigh	0.874	0.125	0.000
N18.4 Chronic kidney disease, stage 4	0.873	0.127	0.000
D50.8 Other iron deficiency anaemias	0.873	0.127	0.000
S42.00 Fracture of clavicle (closed)	0.872	0.128	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.870	0.130	0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified	0.865	0.135	0.000
C51-C58 Malignant neoplasms of female genital organs	0.863	0.137	0.000
Z54 Convalescence	0.861	0.139	0.000
S42.2 Fracture of upper end of humerus	0.859	0.141	0.000
D50.9 Iron deficiency anaemia, unspecified	0.859	0.141	0.000
Y52 Agents primarily affecting the cardiovascular system	0.858	0.142	0.000
Z45.8 Adjustment and management of other implanted devices	0.857	0.143	0.000
Z49 Care involving dialysis	0.855	0.145	0.000
Z50.8 Care involving use of rehabilitation procedures	0.852	0.148	0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.849	0.151	0.000
N20-N23 Urolithiasis	0.847	0.153	0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.843	0.157	0.000
Y43 Primarily systemic agents	0.841	0.159	0.000
A30-A49 Other bacterial diseases	0.839	0.161	0.000
S70 Superficial injury of hip and thigh	0.838	0.162	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.837	0.163	0.000
D00-D09 In situ neoplasms	0.832	0.168	0.000
N28 Other disorders of kidney and ureter, not elsewhere classified	0.830	0.170	0.000
C15-C26 Malignant neoplasms of digestive organs	0.829	0.171	0.000
S31 Open wound of abdomen, lower back and pelvis	0.828	0.172	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.828	0.172	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.826	0.174	0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters	0.824	0.176	0.000
S10 Superficial injury of neck	0.820	0.180	0.000
Z22 Carrier of infectious disease	0.813	0.187	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.810	0.190	0.000
D04 Carcinoma in situ of skin	0.810	0.190	0.000
S42.20 Fracture of upper end of humerus (closed)	0.806	0.194	0.000
N18.5 Chronic kidney disease, stage 5	0.806	0.194	0.000
C56 Malignant neoplasm of ovary	0.806	0.194	0.000
Y48 Anaesthetics and therapeutic gases	0.805	0.194	0.000
X60-X84 Intentional self-harm	0.805	0.195	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.801	0.199	0.000
B35-B49 Mycoses	0.800	0.200	0.000
N11 Chronic tubulo-interstitial nephritis	0.798	0.202	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.798	0.202	0.000
S40 Superficial injury of shoulder and upper arm	0.794	0.206	0.000
Chapter V Mental and behavioural disorders	0.793	0.207	0.000
Z22.3 Carrier of other specified bacterial diseases	0.793	0.207	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.793	0.207	0.000
Z58 Problems related to physical environment	0.792	0.208	0.000
Z49.0 Preparatory care for dialysis	0.791	0.209	0.000
N28.1 Cyst of kidney, acquired	0.787	0.213	0.000
Z56 Problems related to employment and unemployment	0.786	0.214	0.000
Y10-Y34 Event of undetermined intent	0.785	0.215	0.000
Z54.0 Convalescence following surgery	0.783	0.217	0.000
S14 Injury of nerves and spinal cord at neck level	0.782	0.218	0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters	0.782	0.218	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.782	0.218	0.000
Z46 Fitting and adjustment of other devices	0.780	0.220	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.778	0.222	0.000
W50-W64 Exposure to animate mechanical forces	0.778	0.222	0.000
B97.8 Other viral agents as the cause of diseases classified to other chapters	0.777	0.223	0.000
D04.3 Skin of other and unspecified parts of face	0.774	0.226	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.774	0.226	0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters	0.773	0.227	0.000
N13 Obstructive and reflux uropathy	0.769	0.231	0.000
S12 Fracture of neck	0.769	0.231	0.000
S70.0 Contusion of hip	0.767	0.233	0.000
A05 Other bacterial foodborne intoxications	0.767	0.233	0.000
Y43.3 Other antineoplastic drugs	0.767	0.233	0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters	0.767	0.233	0.000
H60 Otitis externa	0.766	0.234	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.766	0.234	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.766	0.234	0.000
N18.8 Other chronic renal failure	0.764	0.235	0.000
T79-T79 Certain early complications of trauma	0.764	0.236	0.000
N26 Unspecified contracted kidney	0.762	0.238	0.000
S41 Open wound of shoulder and upper arm	0.761	0.239	0.000
S20-S29 Injuries to the thorax	0.760	0.240	0.000
D51 Vitamin B12 deficiency anaemia	0.759	0.241	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.759	0.241	0.000
Y57.9 Drug or medicament, unspecified	0.758	0.242	0.000
Y57.5 X-ray contrast media	0.756	0.243	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.754	0.246	0.000
C25 Malignant neoplasm of pancreas	0.754	0.246	0.000
N20 Calculus of kidney and ureter	0.753	0.247	0.000
S19 Other and unspecified injuries of neck	0.753	0.247	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.751	0.249	0.000
S32 Fracture of lumbar spine and pelvis	0.751	0.249	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.750	0.250	0.000
X10-X19 Contact with heat and hot substances	0.748	0.252	0.000
N15 Other renal tubulo-interstitial diseases	0.746	0.254	0.000
S70.9 Superficial injury of hip and thigh, unspecified	0.746	0.254	0.000
A04.4 Other intestinal Escherichia coli infections	0.744	0.256	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.740	0.260	0.000
S10.9 Superficial injury of neck, part unspecified	0.737	0.263	0.000
Z50.4 Psychotherapy, not elsewhere classified	0.735	0.264	0.000
U51 Admission status on psychiatric patients	0.735	0.265	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.734	0.266	0.000
S36 Injury of intra-abdominal organs	0.734	0.266	0.000
B65-B83 Helminthiases	0.732	0.267	0.000
B50-B64 Protozoal diseases	0.732	0.268	0.000
S49.9 Unspecified injury of shoulder and upper arm	0.732	0.268	0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters	0.730	0.270	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.728	0.272	0.000
A49 Bacterial infection of unspecified site	0.727	0.273	0.000
Z44 Fitting and adjustment of external prosthetic device	0.727	0.273	0.000
Y00-Y09 Assault	0.727	0.273	0.000
Y40 Systemic antibiotics	0.726	0.274	0.000
C51 Malignant neoplasm of vulva	0.722	0.278	0.000
Z63 Other problems related to primary support group, including family circumstances	0.721	0.279	0.000
N08 Glomerular disorders in diseases classified elsewhere	0.717	0.283	0.000
C16 Malignant neoplasm of stomach	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
Y35-Y36 Legal intervention and operations of war	0.716	0.284	0.000
X85-X99 Assault	0.716	0.284	0.000
X30-X39 Exposure to forces of nature	0.716	0.284	0.000
X00-X09 Exposure to smoke, fire and flames	0.716	0.284	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.716	0.284	0.000
W75-W84 Other accidental threats to breathing	0.716	0.284	0.000
W65-W74 Accidental drowning and submersion	0.716	0.284	0.000
V98-V99 Other and unspecified transport accidents	0.716	0.284	0.000
V95-V97 Air and space transport accidents	0.716	0.284	0.000
V90-V94 Water transport accidents	0.716	0.284	0.000
V70-V79 Bus occupant injured in transport accident	0.716	0.284	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.716	0.284	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.716	0.284	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.716	0.284	0.000
V01-V09 Pedestrian injured in transport accident	0.716	0.284	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.716	0.284	0.000
H80 Otosclerosis	0.715	0.285	0.000
Y59 Other and unspecified vaccines and biological substances	0.715	0.285	0.000
Y58 Bacterial vaccines	0.715	0.285	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.715	0.285	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.715	0.285	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.715	0.285	0.000
U80 Agent resistant to penicillin and related antibiotics	0.715	0.285	0.000
H82 Vertiginous syndromes in diseases classified elsewhere	0.714	0.286	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.714	0.286	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.714	0.286	0.000
A75-A79 Rickettsioses	0.714	0.286	0.000
A70-A74 Other diseases caused by chlamydiae	0.714	0.286	0.000
A65-A69 Other spirochaetal diseases	0.714	0.286	0.000
A20-A28 Certain zoonotic bacterial diseases	0.714	0.286	0.000
A15-A19 Tuberculosis	0.714	0.286	0.000
H61 Other disorders of external ear	0.714	0.286	0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters	0.714	0.286	0.000
Y54.4 Loop [high-ceiling] diuretics	0.713	0.287	0.000
V80-V89 Other land transport accidents	0.713	0.287	0.000
S80-S89 Injuries to the knee and lower leg	0.712	0.288	0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters	0.711	0.288	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.711	0.289	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.710	0.289	0.000
B99-B99 Other infectious diseases	0.710	0.290	0.000
N03 Chronic nephritic syndrome	0.709	0.291	0.000
Y54.5 Other diuretics	0.709	0.291	0.000
D53 Other nutritional anaemias	0.708	0.292	0.000
H81.9 Disorder of vestibular function, unspecified	0.707	0.293	0.000
H81.8 Other disorders of vestibular function	0.707	0.293	0.000
H81.4 Vertigo of central origin	0.707	0.293	0.000
H81.3 Other peripheral vertigo	0.707	0.293	0.000
N18.1 Chronic kidney disease, stage 1	0.706	0.294	0.000
C64-C68 Malignant neoplasms of urinary tract	0.705	0.295	0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level	0.704	0.295	0.000
Y98 Lifestyle-related condition	0.704	0.295	0.000
Y97 Environmental-pollution-related condition	0.704	0.295	0.000
Y96 Work-related condition	0.704	0.295	0.000
N05 Unspecified nephritic syndrome	0.704	0.296	0.000
T33-T35 Frostbite	0.703	0.297	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.703	0.297	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.703	0.297	0.000
S31.1 Open wound of abdominal wall	0.703	0.297	0.000
R00.1 Bradycardia, unspecified	0.701	0.299	0.000
Z52 Donors of organs and tissues	0.700	0.300	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.700	0.300	0.000
R00 Abnormalities of heart beat	0.697	0.303	0.000
H83.9 Disease of inner ear, unspecified	0.697	0.303	0.000
H83.8 Other specified diseases of inner ear	0.697	0.303	0.000
H83.3 Noise effects on inner ear	0.697	0.303	0.000
H83.2 Labyrinthine dysfunction	0.697	0.303	0.000
H83.1 Labyrinthine fistula	0.697	0.303	0.000
T00-T07 Injuries involving multiple body regions	0.696	0.303	0.000
Y49.2 Other and unspecified antidepressants	0.696	0.304	0.000
T18 Foreign body in alimentary tract	0.694	0.306	0.000
Z45.9 Adjustment and management of unspecified implanted device	0.694	0.306	0.000
Z45.3 Adjustment and management of implanted hearing device	0.694	0.306	0.000
S31.8 Open wound of other and unspecified parts of abdomen	0.693	0.307	0.000
S48 Traumatic amputation of shoulder and upper arm	0.690	0.310	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.690	0.310	0.000
S44 Injury of nerves at shoulder and upper arm level	0.690	0.310	0.000
S47 Crushing injury of shoulder and upper arm	0.690	0.310	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.690	0.310	0.000
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.690	0.310	0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.690	0.310	0.000
D04.4 Skin of scalp and neck	0.689	0.311	0.000
C54 Malignant neoplasm of corpus uteri	0.688	0.312	0.000
V10-V19 Pedal cyclist injured in transport accident	0.687	0.313	0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.686	0.314	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.686	0.314	0.000
V20-V29 Motorcycle rider injured in transport accident	0.686	0.314	0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.686	0.314	0.000
Z59 Problems related to housing and economic circumstances	0.684	0.316	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.683	0.317	0.000
Z50.6 Orthoptic training	0.683	0.317	0.000
Z50.3 Drug rehabilitation	0.683	0.317	0.000
H60.9 Otitis externa, unspecified	0.682	0.318	0.000
N21 Calculus of lower urinary tract	0.681	0.319	0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.681	0.319	0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.681	0.319	0.000
Y52.1 Calcium-channel blockers	0.681	0.319	0.000
Y91 Evidence of alcohol involvement determined by level of intoxication	0.681	0.319	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.680	0.320	0.000
N07 Hereditary nephropathy, not elsewhere classified	0.679	0.321	0.000
N06 Isolated proteinuria with specified morphological lesion	0.679	0.321	0.000
N01 Rapidly progressive nephritic syndrome	0.679	0.321	0.000
N00 Acute nephritic syndrome	0.679	0.321	0.000
S42.9 Fracture of shoulder girdle, part unspecified	0.678	0.322	0.000
X20-X29 Contact with venomous animals and plants	0.678	0.322	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.676	0.324	0.000
Q00-Q07 Congenital malformations of the nervous system	0.676	0.324	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.675	0.325	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.675	0.325	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.675	0.325	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.675	0.325	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.675	0.325	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.675	0.325	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.675	0.325	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.675	0.325	0.000
Y51.0 Anticholinesterase agents	0.675	0.325	0.000
N18.0 End-stage renal disease	0.675	0.325	0.000
Y54.3 Benzothiadiazine derivatives	0.675	0.325	0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters	0.674	0.326	0.000
Z58.1 Exposure to air pollution	0.672	0.328	0.000
N17.8 Other acute renal failure	0.672	0.328	0.000
N17.2 Acute renal failure with medullary necrosis	0.672	0.328	0.000
N17.1 Acute renal failure with acute cortical necrosis	0.672	0.328	0.000
C34 Malignant neoplasm of bronchus and lung	0.672	0.328	0.000
S14.1 Other and unspecified injuries of cervical spinal cord	0.672	0.328	0.000
S17 Crushing injury of neck	0.671	0.329	0.000
S15 Injury of blood vessels at neck level	0.671	0.329	0.000
S11 Open wound of neck	0.671	0.329	0.000
S18 Traumatic amputation at neck level	0.671	0.329	0.000
S16 Injury of muscle and tendon at neck level	0.671	0.329	0.000
Z64 Problems related to certain psychosocial circumstances	0.670	0.330	0.000
Z40 Prophylactic surgery	0.669	0.331	0.000
S50-S59 Injuries to the elbow and forearm	0.669	0.331	0.000
S42.8 Fracture of other parts of shoulder and upper arm	0.669	0.331	0.000
S42.7 Multiple fractures of clavicle, scapula and humerus	0.669	0.331	0.000
A80-A89 Viral infections of the central nervous system	0.668	0.332	0.000
Y48.3 Local anaesthetics	0.668	0.332	0.000
T14 Injury of unspecified body region	0.668	0.332	0.000
S37 Injury of urinary and pelvic organs	0.667	0.332	0.000
Q60-Q64 Congenital malformations of the urinary system	0.667	0.333	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.667	0.333	0.000
A07 Other protozoal intestinal diseases	0.666	0.333	0.000
A06 Amoebiasis	0.666	0.333	0.000
A03 Shigellosis	0.666	0.333	0.000
A01 Typhoid and paratyphoid fevers	0.666	0.333	0.000
A00 Cholera	0.666	0.333	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.665	0.335	0.000
Z46.8 Fitting and adjustment of other specified devices	0.665	0.335	0.000
A40 Streptococcal septicaemia	0.665	0.335	0.000
Z47 Other orthopaedic follow-up care	0.665	0.335	0.000
V40-V49 Car occupant injured in transport accident	0.663	0.337	0.000
R03 Abnormal blood-pressure reading, without diagnosis	0.662	0.338	0.000
B37 Candidiasis	0.660	0.340	0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere	0.658	0.342	0.000
N27 Small kidney of unknown cause	0.658	0.342	0.000
N17.0 Acute renal failure with tubular necrosis	0.657	0.343	0.000
R73 Elevated blood glucose level	0.657	0.343	0.000
X78 Intentional self-harm by sharp object	0.657	0.343	0.000
F80-F89 Disorders of psychological development	0.656	0.343	0.000
C30 Malignant neoplasm of nasal cavity and middle ear	0.656	0.344	0.000
Z58.8 Other problems related to physical environment	0.655	0.345	0.000
Z56.6 Other physical and mental strain related to work	0.655	0.345	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.655	0.345	0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.655	0.345	0.000
N28.0 Ischaemia and infarction of kidney	0.654	0.346	0.000
Z56.0 Unemployment, unspecified	0.654	0.346	0.000
U51.0 Not Previously admitted to a psyciatric hospital	0.654	0.346	0.000
C16.0 Cardia	0.654	0.346	0.000
S71 Open wound of hip and thigh	0.652	0.348	0.000
N02.7 Diffuse crescentic glomerulonephritis	0.651	0.348	0.000
N02.6 Dense deposit disease	0.651	0.348	0.000
N02.5 Diffuse mesangiocapillary glomerulonephritis	0.651	0.348	0.000
N02.4 Diffuse endocapillary proliferative glomerulonephritis	0.651	0.348	0.000
N02.3 Diffuse mesangial proliferative glomerulonephritis	0.651	0.348	0.000
N02.2 Diffuse membranous glomerulonephritis	0.651	0.348	0.000
N02.1 Focal and segmental glomerular lesions	0.651	0.348	0.000
N02.0 Minor glomerular abnormality	0.651	0.348	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.651	0.349	0.000
A05.9 Bacterial foodborne intoxication, unspecified	0.651	0.349	0.000
B07 Viral warts	0.651	0.349	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.650	0.349	0.000
C80 Malignant neoplasm without specification of site	0.650	0.350	0.000
A02 Other Salmonella infections	0.650	0.350	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.650	0.350	0.000
D50.1 Sideropenic dysphagia	0.650	0.350	0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.649	0.351	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.649	0.351	0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.648	0.352	0.000
B49 Unspecified mycosis	0.648	0.352	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.646	0.353	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.646	0.353	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.646	0.353	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.646	0.353	0.000
A04.9 Bacterial intestinal infection, unspecified	0.646	0.354	0.000
A04.6 Enteritis due to Yersinia enterocolitica	0.646	0.354	0.000
A04.3 Enterohaemorrhagic Escherichia coli infection	0.646	0.354	0.000
A04.2 Enteroinvasive Escherichia coli infection	0.646	0.354	0.000
A04.1 Enterotoxigenic Escherichia coli infection	0.646	0.354	0.000
A04.0 Enteropathogenic Escherichia coli infection	0.646	0.354	0.000
C50-C50 Malignant neoplasm of breast	0.646	0.354	0.000
F06.7 Mild cognitive disorder	0.645	0.355	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.645	0.355	0.000
C55 Malignant neoplasm of uterus, part unspecified	0.645	0.355	0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.645	0.355	0.000
S40.0 Contusion of shoulder and upper arm	0.644	0.356	0.000
R03.1 Nonspecific low blood-pressure reading	0.644	0.356	0.000
S42.01 Fracture of clavicle (open)	0.643	0.357	0.000
Z45.1 Adjustment and management of infusion pump	0.643	0.357	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.643	0.357	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.643	0.357	0.000
Y57.8 Other drugs and medicaments	0.641	0.359	0.000
Y57.7 Vitamins, not elsewhere classified	0.641	0.359	0.000
Y57.6 Other diagnostic agents	0.641	0.359	0.000
Y57.4 Pharmaceutical excipients	0.641	0.359	0.000
Y57.3 Alcohol deterrents	0.641	0.359	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.641	0.359	0.000
Y57.1 Lipotropic drugs	0.641	0.359	0.000
Y57.0 Appetite depressants [anorectics]	0.641	0.359	0.000
C57 Malignant neoplasm of other and unspecified female genital organs	0.641	0.359	0.000
S12.7 Multiple fractures of cervical spine	0.641	0.359	0.000
D03 Melanoma in situ	0.641	0.359	0.000
Z65 Problems related to other psychosocial circumstances	0.641	0.359	0.000
Z62 Other problems related to upbringing	0.641	0.359	0.000
Z61 Problems related to negative life events in childhood	0.641	0.359	0.000
Z55 Problems related to education and literacy	0.641	0.359	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.640	0.360	0.000
S80 Superficial injury of lower leg	0.639	0.361	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.636	0.362	0.002
T18.1 Foreign body in oesophagus	0.637	0.363	0.000
B97.6 Parvovirus as the cause of diseases classified to other chapters	0.636	0.364	0.000
B97.5 Reovirus as the cause of diseases classified to other chapters	0.636	0.364	0.000
B97.4 Respiratory synctial virus as the cause of diseases classified to other chapters	0.636	0.364	0.000
B97.3 Retrovirus as the cause of diseases classified to other chapters	0.636	0.364	0.000
B97.2 Coronavirus as the cause of diseases classified to other chapters	0.636	0.364	0.000
B97.1 Enterovirus as the cause of diseases classified to other chapters	0.636	0.364	0.000
B97.0 Adenovirus as the cause of diseases classified to other chapters	0.636	0.364	0.000
U81 Agent resistant to vancomycin and related antibiotics	0.636	0.364	0.000
F60-F69 Disorders of adult personality and behaviour	0.636	0.364	0.000
X50-X57 Overexertion, travel and privation	0.635	0.364	0.000
S31.0 Open wound of lower back and pelvis	0.635	0.365	0.000
S42.3 Fracture of shaft of humerus	0.635	0.365	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.634	0.366	0.000
Z46.6 Fitting and adjustment of urinary device	0.634	0.366	0.000
R73.9 Hyperglycaemia, unspecified	0.633	0.367	0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters	0.632	0.368	0.000
C21 Malignant neoplasm of anus and anal canal	0.632	0.368	0.000
Q43 Other congenital malformations of intestine	0.631	0.369	0.000
Y28 Contact with sharp object, undetermined intent	0.631	0.369	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.629	0.371	0.000
N25 Disorders resulting from impaired renal tubular function	0.629	0.371	0.000
D04.6 Skin of upper limb, including shoulder	0.628	0.372	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.628	0.372	0.000
Y54.9 Mineral salts, not elsewhere classified	0.627	0.372	0.000
Y54.8 Agents affecting uric acid metabolism	0.627	0.372	0.000
Y54.7 Agents affecting calcification	0.627	0.372	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.627	0.372	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.627	0.372	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.627	0.372	0.000
Y54.0 Mineralocorticoids	0.627	0.372	0.000
S78 Traumatic amputation of hip and thigh	0.627	0.373	0.000
S77 Crushing injury of hip and thigh	0.627	0.373	0.000
S76 Injury of muscle and tendon at hip and thigh level	0.627	0.373	0.000
S75 Injury of blood vessels at hip and thigh level	0.627	0.373	0.000
S74 Injury of nerves at hip and thigh level	0.627	0.373	0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.627	0.373	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.627	0.373	0.000
Z49.2 Other dialysis	0.625	0.374	0.000
C20 Malignant neoplasm of rectum	0.625	0.375	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.625	0.375	0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system	0.624	0.376	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.624	0.376	0.000
Q35-Q37 Cleft lip and cleft palate	0.624	0.376	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.624	0.376	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.622	0.378	0.000
C07 Malignant neoplasm of parotid gland	0.622	0.378	0.000
S19.9 Unspecified injury of neck	0.621	0.379	0.000
S20 Superficial injury of thorax	0.621	0.379	0.000
S31.4 Open wound of vagina and vulva	0.621	0.379	0.000
C51.9 Vulva, unspecified	0.621	0.379	0.000
S32.5 Fracture of pubis	0.620	0.380	0.000
Z22.1 Carrier of other intestinal infectious diseases	0.620	0.380	0.000
Y53.4 Other laxatives	0.619	0.381	0.000
W55 Bitten or struck by other mammals	0.619	0.381	0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters	0.619	0.381	0.000
C58 Malignant neoplasm of placenta	0.618	0.381	0.000
C52 Malignant neoplasm of vagina	0.618	0.381	0.000
Z54.9 Convalescence following unspecified treatment	0.617	0.382	0.000
Z54.8 Convalescence following other treatment	0.617	0.382	0.000
Z54.7 Convalescence following combined treatment	0.617	0.382	0.000
Z54.4 Convalescence following treatment of fracture	0.617	0.382	0.000
Z54.3 Convalescence following psychotherapy	0.617	0.382	0.000
Z54.2 Convalescence following chemotherapy	0.617	0.382	0.000
Z54.1 Convalescence following radiotherapy	0.617	0.382	0.000
R00.2 Palpitations	0.617	0.383	0.000
S41.1 Open wound of upper arm	0.617	0.383	0.000
C23 Malignant neoplasm of gallbladder	0.617	0.383	0.000
R74 Abnormal serum enzyme levels	0.616	0.384	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.616	0.384	0.000
N02.8 Other	0.616	0.384	0.000
S42.21 Fracture of upper end of humerus (open)	0.616	0.384	0.000
A04.5 Campylobacter enteritis	0.616	0.384	0.000
B37.4 Candidiasis of other urogenital sites	0.615	0.384	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.615	0.385	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.615	0.385	0.000
Y52.7 Peripheral vasodilators	0.615	0.385	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.615	0.385	0.000
D07 Carcinoma in situ of other and unspecified genital organs	0.615	0.385	0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.615	0.385	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.615	0.385	0.000
D04.2 Skin of ear and external auricular canal	0.614	0.386	0.000
S70.1 Contusion of thigh	0.613	0.387	0.000
S36.1 Injury of liver or gallbladder	0.613	0.387	0.000
Z43 Attention to artificial openings	0.612	0.388	0.000
H81.2 Vestibular neuronitis	0.612	0.388	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.611	0.388	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.611	0.389	0.000
F03 Unspecified dementia	0.611	0.389	0.000
A49.8 Other bacterial infections of unspecified site	0.610	0.390	0.000
Y44 Agents primarily affecting blood constituents	0.609	0.391	0.000
Z46.3 Fitting and adjustment of dental prosthetic device	0.609	0.391	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.609	0.391	0.000
Z28 Immunisation not carried out	0.608	0.391	0.000
Z27 Need for immunisation against combinations of infectious diseases	0.608	0.391	0.000
Z26 Need for immunisation against other single infectious diseases	0.608	0.391	0.000
Z25 Need for immunisation against other single viral diseases	0.608	0.391	0.000
Z24 Need for immunisation against certain single viral diseases	0.608	0.391	0.000
Z23 Need for immunisation against single bacterial diseases	0.608	0.391	0.000
Z20 Contact with and exposure to communicable diseases	0.608	0.391	0.000
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status	0.608	0.391	0.000
N22 Calculus of urinary tract in diseases classified elsewhere	0.608	0.392	0.000
B01 Varicella [chickenpox]	0.607	0.392	0.000
N20.0 Calculus of kidney	0.607	0.393	0.000
C66 Malignant neoplasm of ureter	0.607	0.393	0.000
Y49.5 Other antipsychotics and neuroleptics	0.607	0.393	0.000
C26 Malignant neoplasm of other and ill-defined digestive organs	0.607	0.393	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations