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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs116495174
log Bayes Factor = 16.6303
Chromosome 5   position 92,005,876  (GRCh37) Explore rs116495174 on Ensembl!
Variant rs116495174 is part of Cluster X0124

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
0.999 0.001 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.999 0.001 0.000
Chapter X Diseases of the respiratory system
0.999 0.001 0.000
I95 Hypotension
0.997 0.003 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.991 0.009 0.000
I95.9 Hypotension, unspecified
0.988 0.012 0.000
N17-N19 Renal failure
0.988 0.012 0.000
R50-R69 General symptoms and signs
0.988 0.012 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.987 0.013 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.986 0.014 0.000
N30-N39 Other diseases of urinary system
0.985 0.015 0.000
Chapter I Certain infectious and parasitic diseases
0.984 0.016 0.000
N40-N51 Diseases of male genital organs
0.980 0.020 0.000
Chapter XXI Factors influencing health status and contact with health services
0.978 0.022 0.000
R55 Syncope and collapse
0.978 0.022 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.972 0.028 0.000
Chapter VII Diseases of the eye and adnexa
0.966 0.034 0.000
T81 Complications of procedures, not elsewhere classified
0.965 0.035 0.000
J09-J18 Influenza and pneumonia
0.958 0.042 0.000
N18 Chronic renal failure
0.955 0.045 0.000
I30-I52 Other forms of heart disease
0.955 0.045 0.000
J90-J94 Other diseases of pleura
0.954 0.046 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.950 0.050 0.000
I95.1 Orthostatic hypotension
0.947 0.053 0.000
N18.9 Chronic renal failure, unspecified
0.939 0.061 0.000
J40-J47 Chronic lower respiratory diseases
0.933 0.067 0.000
N40 Hyperplasia of prostate
0.930 0.070 0.000
N30 Cystitis
0.929 0.071 0.000
R59 Enlarged lymph nodes
0.926 0.074 0.000
S80-S89 Injuries to the knee and lower leg
0.926 0.074 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.924 0.076 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.917 0.083 0.000
J44 Other chronic obstructive pulmonary disease
0.916 0.084 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.916 0.084 0.000
Y83.8 Other surgical procedures
0.913 0.087 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.912 0.088 0.000
I60-I69 Cerebrovascular diseases
0.912 0.088 0.000
I34 Nonrheumatic mitral valve disorders
0.910 0.090 0.000
N10-N16 Renal tubulo-interstitial diseases
0.905 0.095 0.000
J18 Pneumonia, organism unspecified
0.905 0.095 0.000
B95-B98 Bacterial, viral and other infectious agents
0.905 0.095 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.905 0.095 0.000
S00-S09 Injuries to the head
0.903 0.097 0.000
N17 Acute renal failure
0.902 0.098 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.899 0.101 0.000
H02 Other disorders of eyelid
0.895 0.105 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.887 0.113 0.000
E70-E90 Metabolic disorders
0.885 0.115 0.000
S20-S29 Injuries to the thorax
0.883 0.117 0.000
R59.0 Localised enlarged lymph nodes
0.881 0.119 0.000
I27 Other pulmonary heart diseases
0.880 0.120 0.000
J18.1 Lobar pneumonia, unspecified
0.880 0.120 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.876 0.124 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.876 0.124 0.000
Y83.6 Removal of other organ (partial) (total)
0.876 0.124 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.871 0.129 0.000
I47 Paroxysmal tachycardia
0.865 0.135 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.865 0.135 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.865 0.135 0.000
I34.0 Mitral (valve) insufficiency
0.864 0.136 0.000
N50 Other disorders of male genital organs
0.859 0.141 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.859 0.141 0.000
J94 Other pleural conditions
0.858 0.142 0.000
N30.2 Other chronic cystitis
0.857 0.143 0.000
Chapter XXII Codes for special purposes
0.855 0.144 0.000
R56 Convulsions, not elsewhere classified
0.855 0.145 0.000
I27.0 Primary pulmonary hypertension
0.855 0.145 0.000
H25-H28 Disorders of lens
0.854 0.146 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.853 0.147 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.851 0.149 0.000
I99 Other and unspecified disorders of circulatory system
0.849 0.151 0.000
Y83.9 Surgical procedure, unspecified
0.844 0.156 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.843 0.156 0.000
I60 Subarachnoid haemorrhage
0.843 0.157 0.000
R52 Pain, not elsewhere classified
0.841 0.159 0.000
N00-N08 Glomerular diseases
0.841 0.159 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.840 0.160 0.000
I67 Other cerebrovascular diseases
0.838 0.162 0.000
Chapter V Mental and behavioural disorders
0.837 0.163 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.837 0.163 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.837 0.163 0.000
A00-A09 Intestinal infectious diseases
0.835 0.165 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.831 0.169 0.000
Z13 Special screening examination for other diseases and disorders
0.831 0.169 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.829 0.171 0.000
W00-W19 Falls
0.828 0.172 0.000
H02.9 Disorder of eyelid, unspecified
0.825 0.175 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.825 0.175 0.000
Chapter VI Diseases of the nervous system
0.825 0.175 0.000
Y83.4 Other reconstructive surgery
0.824 0.176 0.000
E86 Volume depletion
0.823 0.177 0.000
N32 Other disorders of bladder
0.822 0.178 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.822 0.178 0.000
N35 Urethral stricture
0.821 0.179 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.820 0.180 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.818 0.182 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.818 0.182 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.818 0.182 0.000
I05-I09 Chronic rheumatic heart diseases
0.818 0.182 0.000
N45 Orchitis and epididymitis
0.816 0.184 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.816 0.184 0.000
A30-A49 Other bacterial diseases
0.813 0.187 0.000
J92 Pleural plaque
0.811 0.189 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.810 0.190 0.000
N17.9 Acute renal failure, unspecified
0.808 0.192 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.807 0.193 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.806 0.194 0.000
J93 Pneumothorax
0.805 0.195 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.803 0.197 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.802 0.198 0.000
S90-S99 Injuries to the ankle and foot
0.802 0.198 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.799 0.201 0.000
R60 Oedema, not elsewhere classified
0.798 0.201 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.796 0.204 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.794 0.206 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.794 0.206 0.000
J00-J06 Acute upper respiratory infections
0.793 0.207 0.000
S02 Fracture of skull and facial bones
0.792 0.208 0.000
X60-X84 Intentional self-harm
0.792 0.208 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.791 0.209 0.000
J95-J99 Other diseases of the respiratory system
0.791 0.209 0.000
N48 Other disorders of penis
0.790 0.210 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.790 0.210 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.789 0.211 0.000
S06 Intracranial injury
0.788 0.212 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.787 0.213 0.000
N18.4 Chronic kidney disease, stage 4
0.786 0.214 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.786 0.214 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.786 0.214 0.000
N30.8 Other cystitis
0.785 0.215 0.000
I42 Cardiomyopathy
0.785 0.215 0.000
H02.4 Ptosis of eyelid
0.784 0.216 0.000
N31.8 Other neuromuscular dysfunction of bladder
0.784 0.216 0.000
J43 Emphysema
0.784 0.216 0.000
M05-M14 Inflammatory polyarthropathies
0.782 0.218 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.780 0.220 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.777 0.223 0.000
J30-J39 Other diseases of upper respiratory tract
0.776 0.224 0.000
S82 Fracture of lower leg, including ankle
0.775 0.225 0.000
R57 Shock, not elsewhere classified
0.774 0.226 0.000
I67.9 Cerebrovascular disease, unspecified
0.774 0.226 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.773 0.227 0.000
E20-E35 Disorders of other endocrine glands
0.773 0.227 0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm
0.771 0.228 0.000
Z75 Problems related to medical facilities and other health care
0.771 0.229 0.000
J60-J70 Lung diseases due to external agents
0.771 0.229 0.000
H10-H13 Disorders of conjunctiva
0.771 0.229 0.000
N50.8 Other specified disorders of male genital organs
0.770 0.230 0.000
I31 Other diseases of pericardium
0.770 0.230 0.000
S40-S49 Injuries to the shoulder and upper arm
0.769 0.231 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.767 0.232 0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.765 0.235 0.000
N19 Unspecified renal failure
0.762 0.238 0.000
Z00.0 General medical examination
0.761 0.239 0.000
R56.8 Other and unspecified convulsions
0.761 0.239 0.000
B15-B19 Viral hepatitis
0.760 0.240 0.000
E87.5 Hyperkalaemia
0.758 0.242 0.000
A04 Other bacterial intestinal infections
0.758 0.242 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.758 0.242 0.000
M70-M79 Other soft tissue disorders
0.757 0.243 0.000
H55-H59 Other disorders of eye and adnexa
0.757 0.243 0.000
Z01.8 Other specified special examinations
0.757 0.243 0.000
R68 Other general symptoms and signs
0.756 0.243 0.000
B35-B49 Mycoses
0.755 0.244 0.000
S70-S79 Injuries to the hip and thigh
0.755 0.245 0.000
I47.1 Supraventricular tachycardia
0.753 0.247 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.752 0.248 0.000
Chapter VIII Diseases of the ear and mastoid process
0.752 0.248 0.000
J18.0 Bronchopneumonia, unspecified
0.751 0.249 0.000
R20 Disturbances of skin sensation
0.750 0.250 0.000
J11 Influenza, virus not identified
0.747 0.253 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.746 0.254 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.746 0.254 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.746 0.254 0.000
S00 Superficial injury of head
0.744 0.256 0.000
R52.1 Chronic intractable pain
0.743 0.257 0.000
B25-B34 Other viral diseases
0.743 0.257 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.742 0.258 0.000
H26 Other cataract
0.738 0.262 0.000
Z03.8 Observation for other suspected diseases and conditions
0.737 0.263 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.735 0.265 0.000
Y40 Systemic antibiotics
0.734 0.266 0.000
N17.0 Acute renal failure with tubular necrosis
0.733 0.267 0.000
S86 Injury of muscle and tendon at lower leg level
0.733 0.267 0.000
N20-N23 Urolithiasis
0.733 0.267 0.000
V10-V19 Pedal cyclist injured in transport accident
0.733 0.267 0.000
I34.1 Mitral (valve) prolapse
0.733 0.267 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.732 0.268 0.000
J94.2 Haemothorax
0.732 0.268 0.000
T79-T79 Certain early complications of trauma
0.732 0.268 0.000
V20-V29 Motorcycle rider injured in transport accident
0.731 0.269 0.000
H05 Disorders of orbit
0.730 0.270 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.729 0.270 0.000
H01 Other inflammation of eyelid
0.729 0.271 0.000
S29 Other and unspecified injuries of thorax
0.728 0.272 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.728 0.272 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.727 0.273 0.000
Z36 Antenatal screening
0.726 0.274 0.000
H53-H54 Visual disturbances and blindness
0.726 0.274 0.000
N36 Other disorders of urethra
0.726 0.274 0.000
J94.8 Other specified pleural conditions
0.725 0.275 0.000
Y84.6 Urinary catheterisation
0.724 0.276 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.723 0.276 0.000
R23 Other skin changes
0.723 0.277 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.723 0.277 0.000
S50-S59 Injuries to the elbow and forearm
0.722 0.278 0.000
G30-G32 Other degenerative diseases of the nervous system
0.721 0.279 0.000
I45 Other conduction disorders
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.716 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.716 0.283 0.000
Y10-Y34 Event of undetermined intent
0.716 0.283 0.000
Y00-Y09 Assault
0.716 0.283 0.000
X85-X99 Assault
0.716 0.283 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.716 0.283 0.000
X50-X57 Overexertion, travel and privation
0.716 0.283 0.000
X30-X39 Exposure to forces of nature
0.716 0.283 0.000
X20-X29 Contact with venomous animals and plants
0.716 0.283 0.000
X10-X19 Contact with heat and hot substances
0.716 0.283 0.000
X00-X09 Exposure to smoke, fire and flames
0.716 0.283 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.716 0.283 0.000
W75-W84 Other accidental threats to breathing
0.716 0.283 0.000
W65-W74 Accidental drowning and submersion
0.716 0.283 0.000
W50-W64 Exposure to animate mechanical forces
0.716 0.283 0.000
V98-V99 Other and unspecified transport accidents
0.716 0.283 0.000
V95-V97 Air and space transport accidents
0.716 0.283 0.000
V90-V94 Water transport accidents
0.716 0.283 0.000
V80-V89 Other land transport accidents
0.716 0.283 0.000
V70-V79 Bus occupant injured in transport accident
0.716 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.716 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.716 0.283 0.000
V40-V49 Car occupant injured in transport accident
0.716 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.716 0.283 0.000
V01-V09 Pedestrian injured in transport accident
0.716 0.283 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.716 0.284 0.000
Z71.8 Other specified counselling
0.716 0.284 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.716 0.284 0.000
N41 Inflammatory diseases of prostate
0.716 0.284 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.716 0.284 0.000
N02 Recurrent and persistent haematuria
0.716 0.284 0.000
N11 Chronic tubulo-interstitial nephritis
0.715 0.285 0.000
J42 Unspecified chronic bronchitis
0.715 0.285 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.715 0.285 0.000
I95.8 Other hypotension
0.715 0.285 0.000
I95.2 Hypotension due to drugs
0.715 0.285 0.000
I95.0 Idiopathic hypotension
0.715 0.285 0.000
T66-T78 Other and unspecified effects of external causes
0.715 0.285 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.714 0.286 0.000
E87.2 Acidosis
0.713 0.287 0.000
A04.8 Other specified bacterial intestinal infections
0.712 0.288 0.000
N42 Other disorders of prostate
0.712 0.288 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.711 0.288 0.000
I44 Atrioventricular and left bundle-branch block
0.711 0.289 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.710 0.289 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.709 0.291 0.000
R59.1 Generalised enlarged lymph nodes
0.708 0.291 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.708 0.292 0.000
R62 Lack of expected normal physiological development
0.708 0.292 0.000
R64 Cachexia
0.708 0.292 0.000
R58 Haemorrhage, not elsewhere classified
0.708 0.292 0.000
Y57 Other and unspecified drugs and medicaments
0.708 0.292 0.000
I38 Endocarditis, valve unspecified
0.707 0.293 0.000
T87 Complications peculiar to reattachment and amputation
0.707 0.293 0.000
T86 Failure and rejection of transplanted organs and tissues
0.707 0.293 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.707 0.293 0.000
N37 Urethral disorders in diseases classified elsewhere
0.706 0.294 0.000
N34 Urethritis and urethral syndrome
0.706 0.294 0.000
N33 Bladder disorders in diseases classified elsewhere
0.706 0.294 0.000
B99-B99 Other infectious diseases
0.706 0.294 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.706 0.294 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.706 0.294 0.000
B65-B83 Helminthiases
0.706 0.294 0.000
B50-B64 Protozoal diseases
0.706 0.294 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.706 0.294 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.706 0.294 0.000
A80-A89 Viral infections of the central nervous system
0.706 0.294 0.000
A75-A79 Rickettsioses
0.706 0.294 0.000
A70-A74 Other diseases caused by chlamydiae
0.706 0.294 0.000
A65-A69 Other spirochaetal diseases
0.706 0.294 0.000
A20-A28 Certain zoonotic bacterial diseases
0.706 0.294 0.000
A15-A19 Tuberculosis
0.706 0.294 0.000
N18.2 Chronic kidney disease, stage 2
0.705 0.295 0.000
E40-E46 Malnutrition
0.704 0.296 0.000
N35.9 Urethral stricture, unspecified
0.704 0.296 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.703 0.297 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.703 0.297 0.000
I86 Varicose veins of other sites
0.703 0.297 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.703 0.297 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.703 0.297 0.000
N46 Male infertility
0.703 0.297 0.000
N44 Torsion of testis
0.703 0.297 0.000
R51 Headache
0.702 0.298 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.700 0.300 0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.699 0.301 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.698 0.301 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.697 0.302 0.000
Y83.5 Amputation of limb(s)
0.697 0.303 0.000
Y83.0 Surgical operation with transplant of whole organ
0.697 0.303 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.697 0.303 0.000
E83 Disorders of mineral metabolism
0.697 0.303 0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
0.696 0.304 0.000
I83 Varicose veins of lower extremities
0.696 0.304 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.695 0.305 0.000
J93.9 Pneumothorax, unspecified
0.695 0.305 0.000
R53 Malaise and fatigue
0.694 0.305 0.000
H50 Other strabismus
0.693 0.307 0.000
N50.0 Atrophy of testis
0.692 0.308 0.000
W08 Fall involving other furniture
0.692 0.308 0.000
T81.9 Unspecified complication of procedure
0.692 0.308 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.692 0.308 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.692 0.308 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.692 0.308 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.692 0.308 0.000
G90-G99 Other disorders of the nervous system
0.692 0.308 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.691 0.309 0.000
S81 Open wound of lower leg
0.690 0.309 0.000
Z71.6 Tobacco abuse counselling
0.690 0.310 0.000
Y83.3 Surgical operation with formation of external stoma
0.689 0.311 0.000
Y95 Nosocomial condition
0.689 0.311 0.000
J46 Status asthmaticus
0.688 0.311 0.000
M15-M19 Arthrosis
0.688 0.312 0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
0.687 0.313 0.000
H02.0 Entropion and trichiasis of eyelid
0.687 0.313 0.000
Z74 Problems related to care-provider dependency
0.687 0.313 0.000
J17 Pneumonia in diseases classified elsewhere
0.687 0.313 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.687 0.313 0.000
J12 Viral pneumonia, not elsewhere classified
0.687 0.313 0.000
J10 Influenza due to identified influenza virus
0.687 0.313 0.000
J14 Pneumonia due to Haemophilus influenzae
0.687 0.313 0.000
J09 Influenza due to certain identified influenza virus
0.687 0.313 0.000
I81 Portal vein thrombosis
0.687 0.313 0.000
Z22 Carrier of infectious disease
0.686 0.314 0.000
H25 Senile cataract
0.686 0.314 0.000
N32.1 Vesicointestinal fistula
0.686 0.314 0.000
N18.8 Other chronic renal failure
0.685 0.315 0.000
N18.1 Chronic kidney disease, stage 1
0.685 0.315 0.000
I52 Other heart disorders in diseases classified elsewhere
0.684 0.315 0.000
I48 Atrial fibrillation and flutter
0.684 0.315 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.684 0.315 0.000
I41 Myocarditis in diseases classified elsewhere
0.684 0.315 0.000
I40 Acute myocarditis
0.684 0.315 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.684 0.315 0.000
I37 Pulmonary valve disorders
0.684 0.315 0.000
I36 Nonrheumatic tricuspid valve disorders
0.684 0.315 0.000
I32 Pericarditis in diseases classified elsewhere
0.684 0.315 0.000
I30 Acute pericarditis
0.684 0.315 0.000
N30.9 Cystitis, unspecified
0.684 0.316 0.000
N32.8 Other specified disorders of bladder
0.684 0.316 0.000
J91 Pleural effusion in conditions classified elsewhere
0.684 0.316 0.000
S60-S69 Injuries to the wrist and hand
0.684 0.316 0.000
J92.9 Pleural plaque without asbestos
0.683 0.317 0.000
R54 Senility
0.683 0.317 0.000
Z10 Routine general health check-up of defined subpopulation
0.681 0.319 0.000
R79 Other abnormal findings of blood chemistry
0.681 0.319 0.000
I67.1 Cerebral aneurysm, nonruptured
0.680 0.320 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.679 0.321 0.000
J43.9 Emphysema, unspecified
0.677 0.323 0.000
S02.1 Fracture of base of skull
0.676 0.324 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.676 0.324 0.000
E88 Other metabolic disorders
0.676 0.324 0.000
Z13.6 Special screening examination for cardiovascular disorders
0.676 0.324 0.000
N99-N99 Other disorders of the genitourinary system
0.675 0.325 0.000
R60.0 Localised oedema
0.675 0.325 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.674 0.326 0.000
H02.6 Xanthelasma of eyelid
0.672 0.327 0.000
I87 Other disorders of veins
0.672 0.327 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.672 0.328 0.000
E87.3 Alkalosis
0.672 0.328 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.672 0.328 0.000
B02 Zoster [herpes zoster]
0.672 0.328 0.000
F30-F39 Mood [affective] disorders
0.671 0.329 0.000
R22.2 Localised swelling, mass and lump, trunk
0.671 0.329 0.000
E87.6 Hypokalaemia
0.671 0.329 0.000
N32.3 Diverticulum of bladder
0.670 0.329 0.000
M45-M49 Spondylopathies
0.670 0.330 0.000
Z75.1 Person awaiting admission to adequate facility elsewhere
0.670 0.330 0.000
I33 Acute and subacute endocarditis
0.669 0.330 0.000
M86-M90 Other osteopathies
0.669 0.330 0.000
R22.4 Localised swelling, mass and lump, lower limb
0.669 0.331 0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified
0.669 0.331 0.000
J35 Chronic diseases of tonsils and adenoids
0.669 0.331 0.000
J41 Simple and mucopurulent chronic bronchitis
0.669 0.331 0.000
R25 Abnormal involuntary movements
0.669 0.331 0.000
M06 Other rheumatoid arthritis
0.669 0.331 0.000
J00 Acute nasopharyngitis [common cold]
0.669 0.331 0.000
R47-R49 Symptoms and signs involving speech and voice
0.668 0.332 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.668 0.332 0.000
N18.0 End-stage renal disease
0.667 0.332 0.000
N18.5 Chronic kidney disease, stage 5
0.667 0.333 0.000
M80-M85 Disorders of bone density and structure
0.667 0.333 0.000
S91 Open wound of ankle and foot
0.667 0.333 0.000
J34 Other disorders of nose and nasal sinuses
0.666 0.334 0.000
H02.8 Other specified disorders of eyelid
0.666 0.334 0.000
R27 Other lack of coordination
0.666 0.334 0.000
W20-W49 Exposure to inanimate mechanical forces
0.666 0.334 0.000
N30.4 Irradiation cystitis
0.666 0.334 0.000
N30.1 Interstitial cystitis (chronic)
0.666 0.334 0.000
N30.0 Acute cystitis
0.666 0.334 0.000
S89 Other and unspecified injuries of lower leg
0.664 0.336 0.000
S88 Traumatic amputation of lower leg
0.664 0.336 0.000
S87 Crushing injury of lower leg
0.664 0.336 0.000
S85 Injury of blood vessels at lower leg level
0.664 0.336 0.000
S84 Injury of nerves at lower leg level
0.664 0.336 0.000
I62 Other nontraumatic intracranial haemorrhage
0.663 0.337 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.663 0.337 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.663 0.337 0.000
S06.5 Traumatic subdural haemorrhage
0.662 0.338 0.000
N48.8 Other specified disorders of penis
0.662 0.338 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.662 0.338 0.000
H02.5 Other disorders affecting eyelid function
0.661 0.339 0.000
I61 Intracerebral haemorrhage
0.661 0.339 0.000
Z03.9 Observation for suspected disease or condition, unspecified
0.660 0.339 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.660 0.340 0.000
Z36.8 Other antenatal screening
0.660 0.340 0.000
R22.9 Localised swelling, mass and lump, unspecified
0.658 0.342 0.000
T91 Sequelae of injuries of neck and trunk
0.658 0.342 0.000
I28 Other diseases of pulmonary vessels
0.657 0.342 0.000
S82.6 Fracture of lateral malleolus
0.656 0.344 0.000
F80-F89 Disorders of psychological development
0.656 0.344 0.000
I82 Other venous embolism and thrombosis
0.655 0.345 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.654 0.346 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.654 0.346 0.000
Z76 Persons encountering health services in other circumstances
0.654 0.346 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.654 0.346 0.000
J98 Other respiratory disorders
0.653 0.346 0.000
H00 Hordeolum and chalazion
0.653 0.347 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.653 0.347 0.000
J15.2 Pneumonia due to staphylococcus
0.653 0.347 0.000
Z35 Supervision of high-risk pregnancy
0.653 0.347 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.653 0.347 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.653 0.347 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.653 0.347 0.000
Z01.4 Gynaecological examination (general)(routine)
0.653 0.347 0.000
S82.2 Fracture of shaft of tibia
0.653 0.347 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.652 0.348 0.000
Y60.0 During surgical operation
0.652 0.348 0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm
0.652 0.348 0.000
A46 Erysipelas
0.651 0.349 0.000
J04 Acute laryngitis and tracheitis
0.651 0.349 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.649 0.351 0.000
N15 Other renal tubulo-interstitial diseases
0.649 0.351 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.649 0.351 0.000
N10 Acute tubulo-interstitial nephritis
0.649 0.351 0.000
J18.8 Other pneumonia, organism unspecified
0.649 0.351 0.000
J18.2 Hypostatic pneumonia, unspecified
0.649 0.351 0.000
S20 Superficial injury of thorax
0.649 0.351 0.000
J90 Pleural effusion, not elsewhere classified
0.649 0.351 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.648 0.351 0.000
S08 Traumatic amputation of part of head
0.647 0.352 0.000
S07 Crushing injury of head
0.647 0.352 0.000
S05 Injury of eye and orbit
0.647 0.352 0.000
S04 Injury of cranial nerves
0.647 0.352 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.647 0.352 0.000
J20-J22 Other acute lower respiratory infections
0.647 0.352 0.000
N17.8 Other acute renal failure
0.646 0.353 0.000
N17.2 Acute renal failure with medullary necrosis
0.646 0.353 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.646 0.353 0.000
M75 Shoulder lesions
0.645 0.355 0.000
W07 Fall involving chair
0.645 0.355 0.000
H25.8 Other senile cataract
0.644 0.356 0.000
U51 Admission status on psychiatric patients
0.643 0.357 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.643 0.357 0.000
A40 Streptococcal septicaemia
0.643 0.357 0.000
I46 Cardiac arrest
0.642 0.358 0.000
H02.7 Other degenerative disorders of eyelid and periocular area
0.642 0.358 0.000
H02.2 Lagophthalmos
0.642 0.358 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.642 0.358 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.641 0.359 0.000
Z72 Problems related to lifestyle
0.641 0.359 0.000
R52.2 Other chronic pain
0.640 0.360 0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.640 0.360 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.640 0.360 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.640 0.360 0.000
N30.3 Trigonitis
0.640 0.360 0.000
J37 Chronic laryngitis and laryngotracheitis
0.639 0.361 0.000
X78 Intentional self-harm by sharp object
0.638 0.362 0.000
H49 Paralytic strabismus
0.638 0.362 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.637 0.363 0.000
I44.7 Left bundle-branch block, unspecified
0.637 0.363 0.000
I47.2 Ventricular tachycardia
0.636 0.363 0.000
R26 Abnormalities of gait and mobility
0.636 0.364 0.000
Y59 Other and unspecified vaccines and biological substances
0.636 0.364 0.000
Y58 Bacterial vaccines
0.636 0.364 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.636 0.364 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.636 0.364 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.636 0.364 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.636 0.364 0.000
Y52 Agents primarily affecting the cardiovascular system
0.636 0.364 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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