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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs11090206
log Bayes Factor = 13.1737
Chromosome 22   position 20,881,678  (GRCh37) Explore rs11090206 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
M20-M25 Other joint disorders
0.999 0.001 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.999 0.001 0.000
Chapter XX External causes of morbidity and mortality
0.999 0.001 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.998 0.002 0.000
F41 Other anxiety disorders
0.997 0.003 0.000
E10-E14 Diabetes mellitus
0.995 0.005 0.000
Chapter VII Diseases of the eye and adnexa
0.994 0.006 0.000
F30-F39 Mood [affective] disorders
0.994 0.006 0.000
W00-W19 Falls
0.992 0.008 0.000
F41.9 Anxiety disorder, unspecified
0.992 0.008 0.000
M20 Acquired deformities of fingers and toes
0.991 0.009 0.000
E10 Insulin-dependent diabetes mellitus
0.990 0.010 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.988 0.012 0.000
H53-H54 Visual disturbances and blindness
0.988 0.012 0.000
W19 Unspecified fall
0.986 0.014 0.000
F32 Depressive episode
0.986 0.014 0.000
S50-S59 Injuries to the elbow and forearm
0.982 0.018 0.000
H53 Visual disturbances
0.980 0.020 0.000
F32.9 Depressive episode, unspecified
0.978 0.022 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.978 0.022 0.000
W19.9 Unspecified place
0.978 0.022 0.000
H30-H36 Disorders of choroid and retina
0.974 0.026 0.000
H53.8 Other visual disturbances
0.973 0.027 0.000
M25 Other joint disorders, not elsewhere classified
0.972 0.028 0.000
M65-M68 Disorders of synovium and tendon
0.964 0.036 0.000
M25.5 Pain in joint
0.962 0.038 0.000
F41.2 Mixed anxiety and depressive disorder
0.961 0.039 0.000
E10.9 Without complications
0.961 0.039 0.000
S52 Fracture of forearm
0.960 0.040 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.953 0.047 0.000
M25.51 Pain in joint (Shoulder region)
0.945 0.055 0.000
M20.1 Hallux valgus (acquired)
0.943 0.057 0.000
S40-S49 Injuries to the shoulder and upper arm
0.926 0.074 0.000
H35 Other retinal disorders
0.925 0.075 0.000
M65 Synovitis and tenosynovitis
0.919 0.081 0.000
E20-E35 Disorders of other endocrine glands
0.919 0.081 0.000
T39.1 4-Aminophenol derivatives
0.919 0.081 0.000
S52.6 Fracture of lower end of both ulna and radius
0.908 0.092 0.000
M20.4 Other hammer toe(s) (acquired)
0.905 0.095 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.897 0.103 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.895 0.105 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.887 0.113 0.000
E70-E90 Metabolic disorders
0.885 0.115 0.000
W19.2 School, other institution and public administrative area
0.885 0.115 0.000
S60-S69 Injuries to the wrist and hand
0.884 0.116 0.000
E10.4 With neurological complications
0.883 0.117 0.000
M24 Other specific joint derangements
0.882 0.118 0.000
M45-M49 Spondylopathies
0.881 0.119 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.873 0.127 0.000
E14 Unspecified diabetes mellitus
0.871 0.129 0.000
S52.60 Fracture of lower end of both ulna and radius (closed)
0.871 0.129 0.000
X60-X84 Intentional self-harm
0.866 0.134 0.000
F33 Recurrent depressive disorder
0.865 0.135 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.853 0.147 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.852 0.148 0.000
M86-M90 Other osteopathies
0.849 0.151 0.000
H53.9 Visual disturbance, unspecified
0.847 0.153 0.000
M65.3 Trigger finger
0.844 0.156 0.000
M20.2 Hallux rigidus
0.843 0.157 0.000
M25.56 Pain in joint (Lower leg)
0.840 0.160 0.000
H35.3 Degeneration of macula and posterior pole
0.834 0.166 0.000
M50-M54 Other dorsopathies
0.833 0.167 0.000
E83 Disorders of mineral metabolism
0.832 0.168 0.000
H34 Retinal vascular occlusions
0.831 0.169 0.000
H54 Blindness and low vision
0.831 0.169 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.831 0.169 0.000
H53.1 Subjective visual disturbances
0.825 0.175 0.000
S52.0 Fracture of upper end of ulna
0.824 0.176 0.000
S70-S79 Injuries to the hip and thigh
0.824 0.176 0.000
S52.8 Fracture of other parts of forearm
0.824 0.176 0.000
S00-S09 Injuries to the head
0.822 0.178 0.000
F60-F69 Disorders of adult personality and behaviour
0.822 0.178 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.815 0.185 0.000
E14.9 Without complications
0.815 0.185 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.814 0.186 0.000
H33 Retinal detachments and breaks
0.811 0.189 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.811 0.189 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.810 0.190 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.807 0.193 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.806 0.194 0.000
M67 Other disorders of synovium and tendon
0.806 0.194 0.000
M20.3 Other deformity of hallux (acquired)
0.805 0.195 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.805 0.195 0.000
Y42.5 Other oestrogens and progestogens
0.803 0.197 0.000
M31 Other necrotising vasculopathies
0.802 0.198 0.000
T43.2 Other and unspecified antidepressants
0.802 0.198 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.800 0.200 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.795 0.205 0.000
S52.1 Fracture of upper end of radius
0.794 0.206 0.000
E10.5 With peripheral circulatory complications
0.793 0.207 0.000
S10-S19 Injuries to the neck
0.790 0.210 0.000
M65.34 Trigger finger-Hand
0.790 0.210 0.000
M54 Dorsalgia
0.790 0.210 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.788 0.212 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.788 0.212 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.786 0.214 0.000
S20-S29 Injuries to the thorax
0.786 0.214 0.000
W17 Other fall from one level to another
0.784 0.216 0.000
F43 Reaction to severe stress, and adjustment disorders
0.782 0.218 0.000
E10.2 With renal complications
0.780 0.220 0.000
T42.4 Benzodiazepines
0.779 0.221 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.778 0.222 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.777 0.223 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.777 0.223 0.000
S90-S99 Injuries to the ankle and foot
0.776 0.224 0.000
M60-M63 Disorders of muscles
0.776 0.224 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.776 0.224 0.000
T79-T79 Certain early complications of trauma
0.775 0.225 0.000
M25.52 Pain in joint (Upper arm)
0.774 0.226 0.000
E10.1 With ketoacidosis
0.773 0.227 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.773 0.227 0.000
S01 Open wound of head
0.769 0.231 0.000
W19.3 Sports and athletics area
0.767 0.233 0.000
S56 Injury of muscle and tendon at forearm level
0.767 0.233 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.766 0.234 0.000
E83.1 Disorders of iron metabolism
0.766 0.234 0.000
S51 Open wound of forearm
0.766 0.234 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.766 0.234 0.000
M40-M43 Deforming dorsopathies
0.764 0.235 0.000
M46 Other inflammatory spondylopathies
0.763 0.237 0.000
E13 Other specified diabetes mellitus
0.762 0.238 0.000
Y52 Agents primarily affecting the cardiovascular system
0.760 0.240 0.000
M80-M85 Disorders of bone density and structure
0.757 0.243 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.755 0.245 0.000
V10-V19 Pedal cyclist injured in transport accident
0.754 0.246 0.000
Y65 Other misadventures during surgical and medical care
0.754 0.246 0.000
F80-F89 Disorders of psychological development
0.753 0.247 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.752 0.247 0.000
S61 Open wound of wrist and hand
0.752 0.248 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.751 0.248 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.751 0.249 0.000
E10.3 With ophthalmic complications
0.751 0.249 0.000
H35.4 Peripheral retinal degeneration
0.750 0.250 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.748 0.252 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.748 0.252 0.000
Chapter XXII Codes for special purposes
0.746 0.253 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.747 0.253 0.000
H55-H59 Other disorders of eye and adnexa
0.746 0.254 0.000
X78 Intentional self-harm by sharp object
0.746 0.254 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.744 0.256 0.000
M25.8 Other specified joint disorders
0.744 0.256 0.000
H35.5 Hereditary retinal dystrophy
0.744 0.256 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.743 0.256 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.743 0.257 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.742 0.258 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.741 0.259 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.740 0.260 0.000
M21 Other acquired deformities of limbs
0.736 0.264 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.735 0.265 0.000
S40 Superficial injury of shoulder and upper arm
0.735 0.265 0.000
M20.5 Other deformities of toe(s) (acquired)
0.734 0.266 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.733 0.267 0.000
E88 Other metabolic disorders
0.731 0.269 0.000
M91-M94 Chondropathies
0.730 0.270 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.730 0.270 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.730 0.270 0.000
F42 Obsessive-compulsive disorder
0.730 0.270 0.000
S52.00 Fracture of upper end of ulna (closed)
0.727 0.273 0.000
T39.0 Salicylates
0.727 0.273 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.727 0.273 0.000
E21.3 Hyperparathyroidism, unspecified
0.726 0.274 0.000
S52.80 Fracture of other parts of forearm (closed)
0.726 0.274 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.724 0.276 0.000
M24.1 Other articular cartilage disorders
0.724 0.276 0.000
L57.0 Actinic keratosis
0.722 0.278 0.000
Y45.1 Salicylates
0.721 0.279 0.000
H36 Retinal disorders in diseases classified elsewhere
0.720 0.280 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.719 0.281 0.000
E27 Other disorders of adrenal gland
0.719 0.281 0.000
S43.0 Dislocation of shoulder joint
0.718 0.282 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.717 0.283 0.000
F70-F79 Mental retardation
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.716 0.283 0.000
M34 Systemic sclerosis
0.716 0.283 0.000
M33 Dermatopolymyositis
0.716 0.283 0.000
M32 Systemic lupus erythematosus
0.716 0.283 0.000
M30 Polyarteritis nodosa and related conditions
0.716 0.283 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.716 0.283 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.716 0.283 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.716 0.283 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.716 0.283 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.716 0.283 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.716 0.283 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.716 0.283 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.716 0.283 0.000
T36 Poisoning by systemic antibiotics
0.716 0.283 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.716 0.284 0.000
Y35-Y36 Legal intervention and operations of war
0.716 0.284 0.000
Y10-Y34 Event of undetermined intent
0.716 0.284 0.000
Y00-Y09 Assault
0.716 0.284 0.000
X85-X99 Assault
0.716 0.284 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.716 0.284 0.000
X50-X57 Overexertion, travel and privation
0.716 0.284 0.000
X30-X39 Exposure to forces of nature
0.716 0.284 0.000
X20-X29 Contact with venomous animals and plants
0.716 0.284 0.000
X10-X19 Contact with heat and hot substances
0.716 0.284 0.000
X00-X09 Exposure to smoke, fire and flames
0.716 0.284 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.716 0.284 0.000
W75-W84 Other accidental threats to breathing
0.716 0.284 0.000
W65-W74 Accidental drowning and submersion
0.716 0.284 0.000
W50-W64 Exposure to animate mechanical forces
0.716 0.284 0.000
V98-V99 Other and unspecified transport accidents
0.716 0.284 0.000
V95-V97 Air and space transport accidents
0.716 0.284 0.000
V90-V94 Water transport accidents
0.716 0.284 0.000
V70-V79 Bus occupant injured in transport accident
0.716 0.284 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.716 0.284 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.716 0.284 0.000
V40-V49 Car occupant injured in transport accident
0.716 0.284 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.716 0.284 0.000
V01-V09 Pedestrian injured in transport accident
0.716 0.284 0.000
F48 Other neurotic disorders
0.716 0.284 0.000
F44 Dissociative [conversion] disorders
0.716 0.284 0.000
W08 Fall involving other furniture
0.715 0.285 0.000
F41.8 Other specified anxiety disorders
0.715 0.285 0.000
F41.3 Other mixed anxiety disorders
0.715 0.285 0.000
M05-M14 Inflammatory polyarthropathies
0.715 0.285 0.000
F33.0 Recurrent depressive disorder, current episode mild
0.715 0.285 0.000
M25.59 Pain in joint (Site unspecified)
0.714 0.285 0.000
E12 Malnutrition-related diabetes mellitus
0.714 0.286 0.000
F38 Other mood [affective] disorders
0.713 0.287 0.000
F34 Persistent mood [affective] disorders
0.713 0.287 0.000
F30 Manic episode
0.713 0.287 0.000
F39 Unspecified mood [affective] disorder
0.713 0.287 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.712 0.288 0.000
W18 Other fall on same level
0.711 0.289 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.711 0.289 0.000
W15 Fall from cliff
0.711 0.289 0.000
W14 Fall from tree
0.711 0.289 0.000
W12 Fall on and from scaffolding
0.711 0.289 0.000
W11 Fall on and from ladder
0.711 0.289 0.000
W09 Fall involving playground equipment
0.711 0.289 0.000
W05 Fall involving wheelchair
0.711 0.289 0.000
W04 Fall while being carried or supported by other persons
0.711 0.289 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.711 0.289 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.711 0.289 0.000
W00 Fall on same level involving ice and snow
0.711 0.289 0.000
V80-V89 Other land transport accidents
0.711 0.289 0.000
F32.1 Moderate depressive episode
0.710 0.290 0.000
H33.2 Serous retinal detachment
0.710 0.290 0.000
E10.8 With unspecified complications
0.710 0.290 0.000
E10.7 With multiple complications
0.710 0.290 0.000
E10.6 With other specified complications
0.710 0.290 0.000
E10.0 With coma
0.710 0.290 0.000
M48 Other spondylopathies
0.710 0.290 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.709 0.291 0.000
M25.57 Pain in joint (Ankle and foot)
0.709 0.291 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.709 0.291 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.708 0.291 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.708 0.291 0.000
T39.4 Antirheumatics, not elsewhere classified
0.708 0.291 0.000
T39.2 Pyrazolone derivatives
0.708 0.291 0.000
W19.8 Other specified place
0.707 0.293 0.000
W19.5 Trade and service area
0.707 0.293 0.000
W19.0 Home
0.707 0.293 0.000
W19.7 Farm
0.707 0.293 0.000
W19.6 Industrial and construction area
0.707 0.293 0.000
W19.1 Residential institution
0.707 0.293 0.000
F32.8 Other depressive episodes
0.707 0.293 0.000
S42 Fracture of shoulder and upper arm
0.705 0.295 0.000
W10 Fall on and from stairs and steps
0.704 0.296 0.000
S59 Other and unspecified injuries of forearm
0.704 0.296 0.000
S58 Traumatic amputation of forearm
0.704 0.296 0.000
S57 Crushing injury of forearm
0.704 0.296 0.000
S55 Injury of blood vessels at forearm level
0.704 0.296 0.000
S54 Injury of nerves at forearm level
0.704 0.296 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.704 0.296 0.000
H53.6 Night blindness
0.703 0.297 0.000
H53.5 Colour vision deficiencies
0.703 0.297 0.000
H53.3 Other disorders of binocular vision
0.703 0.297 0.000
S01.0 Open wound of scalp
0.703 0.297 0.000
Y59 Other and unspecified vaccines and biological substances
0.701 0.299 0.000
Y58 Bacterial vaccines
0.701 0.299 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.701 0.299 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.701 0.299 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.701 0.299 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.701 0.299 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.701 0.299 0.000
Y48 Anaesthetics and therapeutic gases
0.701 0.299 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.701 0.299 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.701 0.299 0.000
M70-M79 Other soft tissue disorders
0.701 0.299 0.000
S50 Superficial injury of forearm
0.700 0.300 0.000
Chapter VIII Diseases of the ear and mastoid process
0.700 0.300 0.000
S60 Superficial injury of wrist and hand
0.699 0.301 0.000
E34 Other endocrine disorders
0.699 0.301 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.699 0.301 0.000
H31 Other disorders of choroid
0.699 0.301 0.000
H30 Chorioretinal inflammation
0.699 0.301 0.000
W13 Fall from, out of or through building or structure
0.698 0.302 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.698 0.302 0.000
Y44 Agents primarily affecting blood constituents
0.697 0.303 0.000
M25.9 Joint disorder, unspecified
0.697 0.303 0.000
M25.3 Other instability of joint
0.697 0.303 0.000
M25.2 Flail joint
0.697 0.303 0.000
M25.1 Fistula of joint
0.697 0.303 0.000
M25.0 Haemarthrosis
0.697 0.303 0.000
M89 Other disorders of bone
0.696 0.304 0.000
S72 Fracture of femur
0.696 0.304 0.000
H35.8 Other specified retinal disorders
0.694 0.305 0.000
F60 Specific personality disorders
0.694 0.306 0.000
H34.2 Other retinal artery occlusions
0.694 0.306 0.000
V20-V29 Motorcycle rider injured in transport accident
0.692 0.308 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.691 0.309 0.000
M66 Spontaneous rupture of synovium and tendon
0.691 0.309 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.691 0.309 0.000
M87 Osteonecrosis
0.691 0.309 0.000
M25.58 Pain in joint (Other)
0.689 0.311 0.000
E83.5 Disorders of calcium metabolism
0.689 0.311 0.000
W06 Fall involving bed
0.689 0.311 0.000
S52.9 Fracture of forearm, part unspecified
0.688 0.312 0.000
S52.7 Multiple fractures of forearm
0.688 0.312 0.000
S52.4 Fracture of shafts of both ulna and radius
0.688 0.312 0.000
S52.3 Fracture of shaft of radius
0.688 0.312 0.000
S52.2 Fracture of shaft of ulna
0.688 0.312 0.000
E21.0 Primary hyperparathyroidism
0.688 0.312 0.000
M54.9 Dorsalgia, unspecified
0.687 0.313 0.000
M35 Other systemic involvement of connective tissue
0.687 0.313 0.000
Y57 Other and unspecified drugs and medicaments
0.686 0.314 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.685 0.315 0.000
H43-H45 Disorders of vitreous body and globe
0.685 0.315 0.000
Y40 Systemic antibiotics
0.684 0.316 0.000
M67.8 Other specified disorders of synovium and tendon
0.683 0.317 0.000
F32.0 Mild depressive episode
0.682 0.318 0.000
E40-E46 Malnutrition
0.682 0.318 0.000
Y43 Primarily systemic agents
0.682 0.318 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.681 0.319 0.000
E80.4 Gilbert's syndrome
0.680 0.320 0.000
S61.8 Open wound of other parts of wrist and hand
0.679 0.321 0.000
X68 Intentional self-poisoning by and exposure to pesticides
0.679 0.321 0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.678 0.322 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.678 0.322 0.000
E22 Hyperfunction of pituitary gland
0.678 0.322 0.000
E28 Ovarian dysfunction
0.678 0.322 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.677 0.322 0.000
E00-E07 Disorders of thyroid gland
0.677 0.323 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.676 0.324 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.675 0.325 0.000
M22 Disorders of patella
0.675 0.325 0.000
S52.10 Fracture of upper end of radius (closed)
0.675 0.325 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.674 0.325 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.673 0.327 0.000
F31 Bipolar affective disorder
0.673 0.327 0.000
H35.6 Retinal haemorrhage
0.672 0.328 0.000
H54.4 Blindness, one eye
0.672 0.328 0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)
0.671 0.329 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.671 0.329 0.000
S69 Other and unspecified injuries of wrist and hand
0.670 0.330 0.000
E29 Testicular dysfunction
0.670 0.330 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.670 0.330 0.000
H35.0 Background retinopathy and retinal vascular changes
0.669 0.331 0.000
T40.4 Other synthetic narcotics
0.667 0.333 0.000
F41.1 Generalised anxiety disorder
0.666 0.334 0.000
S48 Traumatic amputation of shoulder and upper arm
0.664 0.336 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.664 0.336 0.000
S44 Injury of nerves at shoulder and upper arm level
0.664 0.336 0.000
S41 Open wound of shoulder and upper arm
0.664 0.336 0.000
S47 Crushing injury of shoulder and upper arm
0.664 0.336 0.000
H35.9 Retinal disorder, unspecified
0.663 0.337 0.000
H35.7 Separation of retinal layers
0.663 0.337 0.000
H35.2 Other proliferative retinopathy
0.663 0.337 0.000
H35.1 Retinopathy of prematurity
0.663 0.337 0.000
W07 Fall involving chair
0.663 0.337 0.000
Y54.5 Other diuretics
0.662 0.337 0.000
Chapter I Certain infectious and parasitic diseases
0.660 0.340 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.659 0.341 0.000
M65.8 Other synovitis and tenosynovitis
0.659 0.341 0.000
M65.2 Calcific tendinitis
0.659 0.341 0.000
M65.1 Other infective (teno)synovitis
0.659 0.341 0.000
M65.0 Abscess of tendon sheath
0.659 0.341 0.000
X78.0 Home
0.659 0.341 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.659 0.341 0.000
E32 Diseases of thymus
0.659 0.341 0.000
E31 Polyglandular dysfunction
0.659 0.341 0.000
E30 Disorders of puberty, not elsewhere classified
0.659 0.341 0.000
E26 Hyperaldosteronism
0.659 0.341 0.000
E25 Adrenogenital disorders
0.659 0.341 0.000
E24 Cushing's syndrome
0.659 0.341 0.000
E20 Hypoparathyroidism
0.659 0.341 0.000
Y45.0 Opioids and related analgesics
0.659 0.341 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.658 0.342 0.000
M20.0 Deformity of finger(s)
0.657 0.343 0.000
H54.0 Blindness, both eyes
0.656 0.344 0.000
H34.8 Other retinal vascular occlusions
0.656 0.344 0.000
Y65.4 Failure to introduce or to remove other tube or instrument
0.654 0.346 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.652 0.348 0.000
H53.0 Amblyopia ex anopsia
0.651 0.348 0.000
S52.61 Fracture of lower end of both ulna and radius (open)
0.651 0.349 0.000
T51 Toxic effect of alcohol
0.648 0.352 0.000
E11 Non-insulin-dependent diabetes mellitus
0.647 0.353 0.000
M90 Osteopathies in diseases classified elsewhere
0.646 0.353 0.000
S36 Injury of intra-abdominal organs
0.646 0.354 0.000
E83.4 Disorders of magnesium metabolism
0.646 0.354 0.000
M24.0 Loose body in joint
0.645 0.355 0.000
E50-E64 Other nutritional deficiencies
0.644 0.356 0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)
0.644 0.356 0.000
Y42.9 Other and unspecified hormone antagonists
0.643 0.356 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.643 0.356 0.000
Y42.4 Oral contraceptives
0.643 0.356 0.000
Y42.2 Antithyroid drugs
0.643 0.356 0.000
Y42.1 Thyroid hormones and substitutes
0.643 0.356 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.643 0.356 0.000
F33.9 Recurrent depressive disorder, unspecified
0.643 0.357 0.000
T43.9 Psychotropic drug, unspecified
0.642 0.358 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.642 0.358 0.000
T43.6 Psychostimulants with abuse potential
0.642 0.358 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.642 0.358 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.642 0.358 0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.641 0.358 0.000
T92 Sequelae of injuries of upper limb
0.640 0.360 0.000
M11 Other crystal arthropathies
0.639 0.361 0.000
F99-F99 Unspecified mental disorder
0.636 0.363 0.000
T66-T78 Other and unspecified effects of external causes
0.636 0.364 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.636 0.364 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.636 0.364 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.636 0.364 0.000
T42.3 Barbiturates
0.636 0.364 0.000
T42.2 Succinimides and oxazolidinediones
0.636 0.364 0.000
T42.1 Iminostilbenes
0.636 0.364 0.000
T42.0 Hydantoin derivatives
0.636 0.364 0.000
Y54.3 Benzothiadiazine derivatives
0.636 0.364 0.000
W17.4 Street and highway
0.636 0.364 0.000
E85 Amyloidosis
0.634 0.365 0.000
E84 Cystic fibrosis
0.634 0.365 0.000
E79 Disorders of purine and pyrimidine metabolism
0.634 0.365 0.000
E77 Disorders of glycoprotein metabolism
0.634 0.365 0.000
E76 Disorders of glycosaminoglycan metabolism
0.634 0.365 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.634 0.365 0.000
E74 Other disorders of carbohydrate metabolism
0.634 0.365 0.000
E73 Lactose intolerance
0.634 0.365 0.000
E72 Other disorders of amino-acid metabolism
0.634 0.365 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.634 0.365 0.000
E70 Disorders of aromatic amino-acid metabolism
0.634 0.365 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.634 0.365 0.000
F45 Somatoform disorders
0.634 0.366 0.000
S65 Injury of blood vessels at wrist and hand level
0.633 0.366 0.000
S11 Open wound of neck
0.633 0.367 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.633 0.367 0.000
M24.9 Joint derangement, unspecified
0.633 0.367 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.633 0.367 0.000
M24.7 Protrusio acetabuli
0.633 0.367 0.000
M24.6 Ankylosis of joint
0.633 0.367 0.000
M24.5 Contracture of joint
0.633 0.367 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.633 0.367 0.000
M24.2 Disorder of ligament
0.633 0.367 0.000
M49 Spondylopathies in diseases classified elsewhere
0.632 0.368 0.000
M54.8 Other dorsalgia
0.632 0.368 0.000
M41 Scoliosis
0.631 0.369 0.000
F23 Acute and transient psychotic disorders
0.631 0.369 0.000
Q80-Q89 Other congenital malformations
0.629 0.370 0.000
M45 Ankylosing spondylitis
0.629 0.371 0.000
S01.8 Open wound of other parts of head
0.628 0.372 0.000
S67 Crushing injury of wrist and hand
0.627 0.373 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.626 0.374 0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified
0.626 0.374 0.000
Y45.8 Other analgesics and antipyretics
0.626 0.374 0.000
Y45.5 4-Aminophenol derivatives
0.626 0.374 0.000
Y45.4 Antirheumatics
0.626 0.374 0.000
Y45.2 Propionic acid derivatives
0.626 0.374 0.000
M54.2 Cervicalgia
0.625 0.375 0.000
M54.4 Lumbago with sciatica
0.625 0.375 0.000
S68 Traumatic amputation of wrist and hand
0.625 0.375 0.000
M25.50 Pain in joint (Multiple sites)
0.625 0.375 0.000
M31.6 Other giant cell arteritis
0.625 0.375 0.000
E14.8 With unspecified complications
0.624 0.376 0.000
E14.7 With multiple complications
0.624 0.376 0.000
E14.6 With other specified complications
0.624 0.376 0.000
E14.5 With peripheral circulatory complications
0.624 0.376 0.000
E14.4 With neurological complications
0.624 0.376 0.000
E14.2 Withrenal complications
0.624 0.376 0.000
E14.1 With ketoacidosis
0.624 0.376 0.000
E14.0 With coma
0.624 0.376 0.000
M47 Spondylosis
0.624 0.376 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.624 0.376 0.000
S72.1 Pertrochanteric fracture
0.624 0.376 0.000
S09 Other and unspecified injuries of head
0.622 0.378 0.000
M31.3 Wegener's granulomatosis
0.622 0.378 0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level
0.621 0.379 0.000
X84 Intentional self-harm by unspecified means
0.621 0.379 0.000
X83 Intentional self-harm by other specified means
0.621 0.379 0.000
X82 Intentional self-harm by crashing of motor vehicle
0.621 0.379 0.000
X81 Intentional self-harm by jumping or lying before moving object
0.621 0.379 0.000
X80 Intentional self-harm by jumping from a high place
0.621 0.379 0.000
X79 Intentional self-harm by blunt object
0.621 0.379 0.000
X77 Intentional self-harm by steam, hot vapours and hot objects
0.621 0.379 0.000
X76 Intentional self-harm by smoke, fire and flames
0.621 0.379 0.000
X75 Intentional self-harm by explosive material
0.621 0.379 0.000
X74 Intentional self-harm by other and unspecified firearm discharge
0.621 0.379 0.000
X73 Intentional self-harm by rifle, shotgun and larger firearm discharge
0.621 0.379 0.000
X72 Intentional self-harm by handgun discharge
0.621 0.379 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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