TreeWAS – Variant ID: rs17394246

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
Chapter XV Pregnancy, childbirth and the puerperium	1.000	0.000	0.000
Chapter II Neoplasms	1.000	0.000	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	1.000	0.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	1.000	0.000	0.000
Chapter XX External causes of morbidity and mortality	0.999	0.001	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.999	0.001	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.997	0.003	0.000
E20-E35 Disorders of other endocrine glands	0.997	0.003	0.000
C34 Malignant neoplasm of bronchus and lung	0.994	0.006	0.000
T81 Complications of procedures, not elsewhere classified	0.993	0.007	0.000
Chapter IX Diseases of the circulatory system	0.992	0.008	0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.991	0.009	0.000
Chapter VI Diseases of the nervous system	0.991	0.009	0.000
S00-S09 Injuries to the head	0.990	0.010	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.990	0.010	0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.988	0.012	0.000
I60-I69 Cerebrovascular diseases	0.988	0.012	0.000
G90-G99 Other disorders of the nervous system	0.982	0.018	0.000
E70-E90 Metabolic disorders	0.981	0.019	0.000
Chapter XIV Diseases of the genitourinary system	0.980	0.020	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.979	0.021	0.000
E21.0 Primary hyperparathyroidism	0.977	0.023	0.000
Y83.2 Surgical operation with anastomosis, bypass or graft	0.976	0.024	0.000
C15-C26 Malignant neoplasms of digestive organs	0.974	0.026	0.000
S80-S89 Injuries to the knee and lower leg	0.972	0.028	0.000
M15-M19 Arthrosis	0.972	0.028	0.000
C34.9 Bronchus or lung, unspecified	0.971	0.029	0.000
Chapter I Certain infectious and parasitic diseases	0.968	0.032	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.967	0.033	0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.964	0.036	0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.964	0.036	0.000
E86 Volume depletion	0.957	0.043	0.000
Chapter X Diseases of the respiratory system	0.951	0.049	0.000
I10-I15 Hypertensive diseases	0.950	0.050	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.944	0.056	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.944	0.056	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.943	0.057	0.000
A00-A09 Intestinal infectious diseases	0.940	0.060	0.000
C34.1 Upper lobe, bronchus or lung	0.939	0.061	0.000
N00-N08 Glomerular diseases	0.938	0.062	0.000
I12 Hypertensive renal disease	0.938	0.062	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.934	0.066	0.000
I69 Sequelae of cerebrovascular disease	0.933	0.067	0.000
T84.0 Mechanical complication of internal joint prosthesis	0.933	0.067	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.929	0.071	0.000
G95 Other diseases of spinal cord	0.929	0.071	0.000
O32.1 Maternal care for breech presentation	0.928	0.072	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.922	0.078	0.000
Y83.1 Surgical operation with implant of artificial internal device	0.920	0.080	0.000
J09-J18 Influenza and pneumonia	0.920	0.080	0.000
I12.0 Hypertensive renal disease with renal failure	0.919	0.081	0.000
C18 Malignant neoplasm of colon	0.918	0.082	0.000
N20-N23 Urolithiasis	0.915	0.085	0.000
A04 Other bacterial intestinal infections	0.913	0.087	0.000
N60-N64 Disorders of breast	0.911	0.089	0.000
D45 Polycythaemia vera	0.911	0.089	0.000
S00 Superficial injury of head	0.908	0.092	0.000
M20-M25 Other joint disorders	0.905	0.095	0.000
I67 Other cerebrovascular diseases	0.904	0.096	0.000
O46.9 Antepartum haemorrhage, unspecified	0.904	0.096	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.904	0.096	0.000
M65-M68 Disorders of synovium and tendon	0.901	0.099	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.901	0.099	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.893	0.107	0.000
O60-O75 Complications of labour and delivery	0.893	0.107	0.000
M16 Coxarthrosis [arthrosis of hip]	0.891	0.109	0.000
S02 Fracture of skull and facial bones	0.891	0.109	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.890	0.110	0.000
S01 Open wound of head	0.889	0.111	0.000
M40-M43 Deforming dorsopathies	0.887	0.113	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.884	0.116	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.879	0.121	0.000
G99 Other disorders of nervous system in diseases classified elsewhere	0.879	0.121	0.000
Y95 Nosocomial condition	0.878	0.122	0.000
M45-M49 Spondylopathies	0.877	0.123	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.874	0.126	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.874	0.126	0.000
E21.3 Hyperparathyroidism, unspecified	0.873	0.127	0.000
G93 Other disorders of brain	0.870	0.129	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.870	0.130	0.000
A04.8 Other specified bacterial intestinal infections	0.870	0.130	0.000
C32 Malignant neoplasm of larynx	0.868	0.132	0.000
E27 Other disorders of adrenal gland	0.865	0.135	0.000
J90-J94 Other diseases of pleura	0.863	0.137	0.000
T81.9 Unspecified complication of procedure	0.863	0.137	0.000
E23 Hypofunction and other disorders of pituitary gland	0.861	0.139	0.000
M17 Gonarthrosis [arthrosis of knee]	0.861	0.139	0.000
Y52 Agents primarily affecting the cardiovascular system	0.855	0.145	0.000
M86-M90 Other osteopathies	0.854	0.146	0.000
N63 Unspecified lump in breast	0.854	0.146	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.852	0.148	0.000
S82 Fracture of lower leg, including ankle	0.851	0.149	0.000
C25 Malignant neoplasm of pancreas	0.850	0.150	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.848	0.152	0.000
J95-J99 Other diseases of the respiratory system	0.848	0.152	0.000
N02 Recurrent and persistent haematuria	0.847	0.153	0.000
J13 Pneumonia due to Streptococcus pneumoniae	0.845	0.155	0.000
O68 Labour and delivery complicated by foetal stress [distress]	0.845	0.155	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.844	0.156	0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.843	0.157	0.000
N25-N29 Other disorders of kidney and ureter	0.842	0.158	0.000
I67.8 Other specified cerebrovascular diseases	0.841	0.159	0.000
Y83.9 Surgical procedure, unspecified	0.840	0.160	0.000
T81.8 Other complications of procedures, not elsewhere classified	0.837	0.163	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.836	0.164	0.000
T81.4 Infection following a procedure, not elsewhere classified	0.834	0.166	0.000
S00.1 Contusion of eyelid and periocular area	0.833	0.167	0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.833	0.167	0.000
G81 Hemiplegia	0.832	0.168	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.831	0.169	0.000
M16.0 Primary coxarthrosis, bilateral	0.830	0.170	0.000
S40-S49 Injuries to the shoulder and upper arm	0.829	0.171	0.000
N20 Calculus of kidney and ureter	0.828	0.172	0.000
Chapter V Mental and behavioural disorders	0.827	0.173	0.000
M24 Other specific joint derangements	0.825	0.175	0.000
N03 Chronic nephritic syndrome	0.824	0.176	0.000
O45 Premature separation of placenta [abruptio placentae]	0.824	0.176	0.000
O41 Other disorders of amniotic fluid and membranes	0.823	0.176	0.000
C15 Malignant neoplasm of oesophagus	0.823	0.177	0.000
C18.7 Sigmoid colon	0.822	0.178	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.821	0.178	0.000
N30-N39 Other diseases of urinary system	0.820	0.180	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.820	0.180	0.000
M91-M94 Chondropathies	0.819	0.181	0.000
O36 Maternal care for other known or suspected foetal problems	0.819	0.181	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.816	0.184	0.000
X50-X57 Overexertion, travel and privation	0.815	0.185	0.000
M43 Other deforming dorsopathies	0.814	0.186	0.000
O40 Polyhydramnios	0.814	0.186	0.000
O43 Placental disorders	0.814	0.186	0.000
S50-S59 Injuries to the elbow and forearm	0.813	0.187	0.000
M17.1 Other primary gonarthrosis	0.811	0.189	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.807	0.193	0.000
I12.9 Hypertensive renal disease without renal failure	0.805	0.195	0.000
G99.2 Myelopathy in diseases classified elsewhere	0.805	0.195	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.803	0.197	0.000
G80 Infantile cerebral palsy	0.803	0.197	0.000
S82.1 Fracture of upper end of tibia	0.803	0.197	0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.799	0.201	0.000
E87.1 Hypo-osmolality and hyponatraemia	0.797	0.203	0.000
M80-M85 Disorders of bone density and structure	0.797	0.203	0.000
G95.9 Disease of spinal cord, unspecified	0.795	0.205	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.795	0.205	0.000
G20-G26 Extrapyramidal and movement disorders	0.793	0.207	0.000
S01.8 Open wound of other parts of head	0.793	0.207	0.000
A04.5 Campylobacter enteritis	0.790	0.210	0.000
C34.0 Main bronchus	0.788	0.212	0.000
A08 Viral and other specified intestinal infections	0.787	0.212	0.000
Y00-Y09 Assault	0.782	0.218	0.000
D10-D36 Benign neoplasms	0.782	0.218	0.000
N02.9 Unspecified	0.782	0.218	0.000
I26 Pulmonary embolism	0.782	0.218	0.000
S89 Other and unspecified injuries of lower leg	0.781	0.219	0.000
T86 Failure and rejection of transplanted organs and tissues	0.781	0.219	0.000
J15 Bacterial pneumonia, not elsewhere classified	0.780	0.220	0.000
J00-J06 Acute upper respiratory infections	0.779	0.221	0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.779	0.221	0.000
O30 Multiple gestation	0.778	0.222	0.000
N64 Other disorders of breast	0.777	0.223	0.000
N32 Other disorders of bladder	0.776	0.224	0.000
G95.0 Syringomyelia and syringobulbia	0.775	0.225	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.772	0.227	0.001
T36-T50 Poisoning by drugs, medicaments and biological substances	0.773	0.227	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.773	0.227	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.772	0.227	0.000
T93 Sequelae of injuries of lower limb	0.772	0.228	0.000
T84.1 Mechanical complication of internal fixation device of bones of limb	0.772	0.228	0.000
J18 Pneumonia, organism unspecified	0.771	0.229	0.000
S06 Intracranial injury	0.770	0.230	0.000
N23 Unspecified renal colic	0.770	0.230	0.000
M66 Spontaneous rupture of synovium and tendon	0.770	0.230	0.000
S02.4 Fracture of malar and maxillary bones	0.770	0.230	0.000
B15-B19 Viral hepatitis	0.769	0.231	0.000
S82.10 Fracture of upper end of tibia (closed)	0.768	0.232	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.768	0.232	0.000
G81.9 Hemiplegia, unspecified	0.767	0.233	0.000
S80 Superficial injury of lower leg	0.766	0.234	0.000
T87 Complications peculiar to reattachment and amputation	0.766	0.234	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.766	0.234	0.000
Chapter XXII Codes for special purposes	0.765	0.235	0.000
W50-W64 Exposure to animate mechanical forces	0.765	0.235	0.000
E23.0 Hypopituitarism	0.764	0.236	0.000
B35-B49 Mycoses	0.764	0.236	0.000
Y42.5 Other oestrogens and progestogens	0.764	0.236	0.000
N20.0 Calculus of kidney	0.763	0.237	0.000
G95.1 Vascular myelopathies	0.763	0.237	0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.761	0.239	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.760	0.239	0.000
E85 Amyloidosis	0.760	0.239	0.000
C32.9 Larynx, unspecified	0.759	0.241	0.000
M19 Other arthrosis	0.759	0.241	0.000
I95 Hypotension	0.757	0.243	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.757	0.243	0.000
I11 Hypertensive heart disease	0.757	0.243	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.757	0.243	0.000
E65-E68 Obesity and other hyperalimentation	0.757	0.243	0.000
E88 Other metabolic disorders	0.756	0.244	0.000
V20-V29 Motorcycle rider injured in transport accident	0.756	0.244	0.000
V80-V89 Other land transport accidents	0.755	0.245	0.000
S02.6 Fracture of mandible	0.754	0.245	0.000
E89.0 Postprocedural hypothyroidism	0.753	0.247	0.000
M18 Arthrosis of first carpometacarpal joint	0.753	0.247	0.000
M65 Synovitis and tenosynovitis	0.753	0.247	0.000
D23 Other benign neoplasms of skin	0.752	0.248	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.752	0.248	0.000
D36 Benign neoplasm of other and unspecified sites	0.752	0.248	0.000
M60-M63 Disorders of muscles	0.751	0.248	0.000
C34.3 Lower lobe, bronchus or lung	0.750	0.250	0.000
C18.9 Colon, unspecified	0.750	0.250	0.000
E89.2 Postprocedural hypoparathyroidism	0.750	0.250	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.749	0.251	0.000
M48 Other spondylopathies	0.747	0.253	0.000
S10-S19 Injuries to the neck	0.746	0.254	0.000
Q60-Q64 Congenital malformations of the urinary system	0.745	0.255	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.745	0.255	0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.744	0.255	0.000
S83.2 Tear of meniscus, current	0.744	0.256	0.000
Y83.3 Surgical operation with formation of external stoma	0.744	0.256	0.000
N32.9 Bladder disorder, unspecified	0.744	0.256	0.000
N28 Other disorders of kidney and ureter, not elsewhere classified	0.743	0.257	0.000
N03.9 Unspecified	0.743	0.257	0.000
J90 Pleural effusion, not elsewhere classified	0.743	0.257	0.000
M35 Other systemic involvement of connective tissue	0.742	0.258	0.000
Y83.8 Other surgical procedures	0.742	0.258	0.000
O26 Maternal care for other conditions predominantly related to pregnancy	0.741	0.259	0.000
O61 Failed induction of labour	0.741	0.259	0.000
J91 Pleural effusion in conditions classified elsewhere	0.741	0.259	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.741	0.259	0.000
O34.2 Maternal care due to uterine scar from previous surgery	0.740	0.260	0.000
M05-M14 Inflammatory polyarthropathies	0.740	0.260	0.000
C18.4 Transverse colon	0.739	0.261	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.739	0.261	0.000
S09 Other and unspecified injuries of head	0.739	0.261	0.000
T66-T78 Other and unspecified effects of external causes	0.738	0.261	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.738	0.262	0.000
M43.1 Spondylolisthesis	0.737	0.263	0.000
M21 Other acquired deformities of limbs	0.737	0.263	0.000
X20-X29 Contact with venomous animals and plants	0.736	0.264	0.000
Chapter VIII Diseases of the ear and mastoid process	0.736	0.264	0.000
G96 Other disorders of central nervous system	0.735	0.265	0.000
E22 Hyperfunction of pituitary gland	0.734	0.265	0.000
O32.0 Maternal care for unstable lie	0.734	0.266	0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.734	0.266	0.000
C25.0 Head of pancreas	0.733	0.267	0.000
O48 Prolonged pregnancy	0.733	0.267	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.733	0.267	0.000
I61 Intracerebral haemorrhage	0.732	0.268	0.000
S05 Injury of eye and orbit	0.732	0.268	0.000
S81 Open wound of lower leg	0.732	0.268	0.000
N61 Inflammatory disorders of breast	0.731	0.269	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.731	0.269	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.727	0.273	0.000
D36.1 Peripheral nerves and autonomic nervous system	0.727	0.273	0.000
C43 Malignant melanoma of skin	0.726	0.274	0.000
B07 Viral warts	0.726	0.274	0.000
M89 Other disorders of bone	0.725	0.275	0.000
M47 Spondylosis	0.724	0.276	0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.723	0.277	0.000
I62 Other nontraumatic intracranial haemorrhage	0.723	0.277	0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.723	0.277	0.000
J18.9 Pneumonia, unspecified	0.720	0.280	0.000
O47 False labour	0.720	0.280	0.000
E00-E07 Disorders of thyroid gland	0.720	0.280	0.000
T82.3 Mechanical complication of other vascular grafts	0.718	0.282	0.000
I27 Other pulmonary heart diseases	0.717	0.283	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.717	0.283	0.000
T33-T35 Frostbite	0.717	0.283	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.717	0.283	0.000
T00-T07 Injuries involving multiple body regions	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
O85-O92 Complications predominantly related to the puerperium	0.717	0.283	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.717	0.283	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.717	0.283	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.717	0.283	0.000
M00-M03 Infectious arthropathies	0.717	0.283	0.000
G80.9 Infantile cerebral palsy, unspecified	0.717	0.283	0.000
O44 Placenta praevia	0.717	0.283	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.717	0.283	0.000
O33 Maternal care for known or suspected disproportion	0.717	0.283	0.000
O31 Complications specific to multiple gestation	0.717	0.283	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.717	0.283	0.000
Y35-Y36 Legal intervention and operations of war	0.717	0.283	0.000
Y10-Y34 Event of undetermined intent	0.717	0.283	0.000
X85-X99 Assault	0.717	0.283	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.717	0.283	0.000
X30-X39 Exposure to forces of nature	0.717	0.283	0.000
X10-X19 Contact with heat and hot substances	0.717	0.283	0.000
X00-X09 Exposure to smoke, fire and flames	0.717	0.283	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.717	0.283	0.000
W75-W84 Other accidental threats to breathing	0.717	0.283	0.000
W65-W74 Accidental drowning and submersion	0.717	0.283	0.000
V98-V99 Other and unspecified transport accidents	0.717	0.283	0.000
V95-V97 Air and space transport accidents	0.717	0.283	0.000
V90-V94 Water transport accidents	0.717	0.283	0.000
V70-V79 Bus occupant injured in transport accident	0.717	0.283	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.717	0.283	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.717	0.283	0.000
V40-V49 Car occupant injured in transport accident	0.717	0.283	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.717	0.283	0.000
V01-V09 Pedestrian injured in transport accident	0.717	0.283	0.000
S01.0 Open wound of scalp	0.715	0.285	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.715	0.285	0.000
O62 Abnormalities of forces of labour	0.715	0.285	0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.715	0.285	0.000
C38 Malignant neoplasm of heart, mediastinum and pleura	0.715	0.285	0.000
C31 Malignant neoplasm of accessory sinuses	0.715	0.285	0.000
C30 Malignant neoplasm of nasal cavity and middle ear	0.715	0.285	0.000
C37 Malignant neoplasm of thymus	0.715	0.285	0.000
C33 Malignant neoplasm of trachea	0.715	0.285	0.000
Y83.0 Surgical operation with transplant of whole organ	0.715	0.285	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.715	0.285	0.000
E34 Other endocrine disorders	0.715	0.285	0.000
E32 Diseases of thymus	0.715	0.285	0.000
E31 Polyglandular dysfunction	0.715	0.285	0.000
E30 Disorders of puberty, not elsewhere classified	0.715	0.285	0.000
E28 Ovarian dysfunction	0.715	0.285	0.000
E26 Hyperaldosteronism	0.715	0.285	0.000
E25 Adrenogenital disorders	0.715	0.285	0.000
E24 Cushing's syndrome	0.715	0.285	0.000
E20 Hypoparathyroidism	0.715	0.285	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.714	0.286	0.000
T81.3 Disruption of operation wound, not elsewhere classified	0.714	0.286	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.714	0.286	0.000
N04 Nephrotic syndrome	0.714	0.286	0.000
J93 Pneumothorax	0.713	0.287	0.000
J95 Postprocedural respiratory disorders, not elsewhere classified	0.712	0.287	0.000
C34.8 Overlapping lesion of bronchus and lung	0.712	0.288	0.000
C34.2 Middle lobe, bronchus or lung	0.712	0.288	0.000
T81.7 Vascular complications following a procedure, not elsewhere classified	0.712	0.288	0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure	0.712	0.288	0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.712	0.288	0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified	0.712	0.288	0.000
I00-I02 Acute rheumatic fever	0.712	0.288	0.000
T90 Sequelae of injuries of head	0.712	0.288	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.711	0.289	0.000
S90-S99 Injuries to the ankle and foot	0.710	0.289	0.000
G70-G73 Diseases of myoneural junction and muscle	0.710	0.290	0.000
S08 Traumatic amputation of part of head	0.710	0.290	0.000
S07 Crushing injury of head	0.710	0.290	0.000
S04 Injury of cranial nerves	0.710	0.290	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.710	0.290	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.709	0.290	0.000
E21.4 Other specified disorders of parathyroid gland	0.709	0.290	0.000
E21.2 Other hyperparathyroidism	0.709	0.290	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.709	0.290	0.000
E29 Testicular dysfunction	0.709	0.291	0.000
D41.4 Bladder	0.709	0.291	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.709	0.291	0.000
Y83.5 Amputation of limb(s)	0.708	0.291	0.000
I69.3 Sequelae of cerebral infarction	0.708	0.292	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.708	0.292	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.708	0.292	0.000
D23.1 Skin of eyelid, including canthus	0.708	0.292	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.707	0.293	0.000
C18.6 Descending colon	0.707	0.293	0.000
A02 Other Salmonella infections	0.706	0.294	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.706	0.294	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.705	0.295	0.000
N99-N99 Other disorders of the genitourinary system	0.705	0.295	0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.705	0.295	0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.705	0.295	0.000
G94 Other disorders of brain in diseases classified elsewhere	0.704	0.296	0.000
G90 Disorders of autonomic nervous system	0.704	0.296	0.000
G98 Other disorders of nervous system, not elsewhere classified	0.704	0.296	0.000
G92 Toxic encephalopathy	0.704	0.296	0.000
J86 Pyothorax	0.704	0.296	0.000
S00.0 Superficial injury of scalp	0.704	0.296	0.000
E84 Cystic fibrosis	0.704	0.296	0.000
E79 Disorders of purine and pyrimidine metabolism	0.704	0.296	0.000
E77 Disorders of glycoprotein metabolism	0.704	0.296	0.000
E76 Disorders of glycosaminoglycan metabolism	0.704	0.296	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.704	0.296	0.000
E74 Other disorders of carbohydrate metabolism	0.704	0.296	0.000
E73 Lactose intolerance	0.704	0.296	0.000
E72 Other disorders of amino-acid metabolism	0.704	0.296	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.704	0.296	0.000
E70 Disorders of aromatic amino-acid metabolism	0.704	0.296	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.704	0.296	0.000
S83.6 Sprain and strain of other and unspecified parts of knee	0.704	0.296	0.000
M16.7 Other secondary coxarthrosis	0.703	0.297	0.000
N08 Glomerular disorders in diseases classified elsewhere	0.703	0.297	0.000
I67.2 Cerebral atherosclerosis	0.703	0.297	0.000
G95.2 Cord compression, unspecified	0.703	0.297	0.000
D46 Myelodysplastic syndromes	0.702	0.298	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.702	0.298	0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.702	0.298	0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.702	0.298	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.702	0.298	0.000
I67.9 Cerebrovascular disease, unspecified	0.701	0.299	0.000
S02.5 Fracture of tooth	0.700	0.299	0.000
S01.3 Open wound of ear	0.700	0.300	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.699	0.301	0.000
C21 Malignant neoplasm of anus and anal canal	0.699	0.301	0.000
C17 Malignant neoplasm of small intestine	0.699	0.301	0.000
C23 Malignant neoplasm of gallbladder	0.699	0.301	0.000
O45.9 Premature separation of placenta, unspecified	0.698	0.302	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.698	0.302	0.000
T79-T79 Certain early complications of trauma	0.698	0.302	0.000
N32.3 Diverticulum of bladder	0.697	0.303	0.000
S88 Traumatic amputation of lower leg	0.697	0.303	0.000
S87 Crushing injury of lower leg	0.697	0.303	0.000
S86 Injury of muscle and tendon at lower leg level	0.697	0.303	0.000
S85 Injury of blood vessels at lower leg level	0.697	0.303	0.000
S84 Injury of nerves at lower leg level	0.697	0.303	0.000
Y40 Systemic antibiotics	0.697	0.303	0.000
S01.9 Open wound of head, part unspecified	0.697	0.303	0.000
M15 Polyarthrosis	0.697	0.303	0.000
A80-A89 Viral infections of the central nervous system	0.696	0.304	0.000
G91 Hydrocephalus	0.696	0.304	0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.696	0.304	0.000
B99-B99 Other infectious diseases	0.694	0.306	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.694	0.306	0.000
B65-B83 Helminthiases	0.694	0.306	0.000
B50-B64 Protozoal diseases	0.694	0.306	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.694	0.306	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.694	0.306	0.000
A75-A79 Rickettsioses	0.694	0.306	0.000
A70-A74 Other diseases caused by chlamydiae	0.694	0.306	0.000
A65-A69 Other spirochaetal diseases	0.694	0.306	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.694	0.306	0.000
A20-A28 Certain zoonotic bacterial diseases	0.694	0.306	0.000
A15-A19 Tuberculosis	0.694	0.306	0.000
G93.1 Anoxic brain damage, not elsewhere classified	0.694	0.306	0.000
M25 Other joint disorders, not elsewhere classified	0.694	0.306	0.000
G93.0 Cerebral cysts	0.694	0.306	0.000
O32.9 Maternal care for malpresentation of foetus, unspecified	0.693	0.306	0.000
O32.8 Maternal care for other malpresentation of foetus	0.693	0.306	0.000
O32.6 Maternal care for compound presentation	0.693	0.306	0.000
O32.4 Maternal care for high head at term	0.693	0.306	0.000
O32.3 Maternal care for face, brow and chin presentation	0.693	0.306	0.000
O32.2 Maternal care for transverse and oblique lie	0.693	0.306	0.000
N28.9 Disorder of kidney and ureter, unspecified	0.692	0.308	0.000
N35 Urethral stricture	0.691	0.308	0.000
C18.5 Splenic flexure	0.691	0.309	0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.691	0.309	0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.691	0.309	0.000
T84.3 Mechanical complication of other bone devices, implants and grafts	0.691	0.309	0.000
G95.8 Other specified diseases of spinal cord	0.690	0.310	0.000
S00.3 Superficial injury of nose	0.690	0.310	0.000
M93 Other osteochondropathies	0.689	0.311	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.689	0.311	0.000
C26 Malignant neoplasm of other and ill-defined digestive organs	0.689	0.311	0.000
C18.3 Hepatic flexure	0.689	0.311	0.000
G93.9 Disorder of brain, unspecified	0.688	0.312	0.000
O23 Infections of genito-urinary tract in pregnancy	0.688	0.312	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.688	0.312	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.688	0.312	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.688	0.312	0.000
J99 Respiratory disorders in diseases classified elsewhere	0.688	0.312	0.000
I95.1 Orthostatic hypotension	0.687	0.313	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.686	0.314	0.000
X60-X84 Intentional self-harm	0.685	0.314	0.000
M16.3 Other dysplastic coxarthrosis	0.685	0.315	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.685	0.315	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.685	0.315	0.000
G30-G32 Other degenerative diseases of the nervous system	0.684	0.315	0.000
C15.5 Lower third of oesophagus	0.684	0.316	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.683	0.316	0.000
M46 Other inflammatory spondylopathies	0.683	0.317	0.000
X51 Travel and motion	0.682	0.317	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.682	0.318	0.000
A30-A49 Other bacterial diseases	0.682	0.318	0.000
I15 Secondary hypertension	0.681	0.319	0.000
I13 Hypertensive heart and renal disease	0.681	0.319	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.681	0.319	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.681	0.319	0.000
W00-W19 Falls	0.681	0.319	0.000
O41.0 Oligohydramnios	0.680	0.320	0.000
E27.9 Disorder of adrenal gland, unspecified	0.680	0.320	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.680	0.320	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.679	0.321	0.000
E40-E46 Malnutrition	0.679	0.321	0.000
V10-V19 Pedal cyclist injured in transport accident	0.679	0.321	0.000
O15 Eclampsia	0.677	0.323	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.677	0.323	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.677	0.323	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.677	0.323	0.000
O46.8 Other antepartum haemorrhage	0.677	0.323	0.000
O46.0 Antepartum haemorrhage with coagulation defect	0.677	0.323	0.000
Y59 Other and unspecified vaccines and biological substances	0.676	0.324	0.000
Y58 Bacterial vaccines	0.676	0.324	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.676	0.324	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.676	0.324	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.676	0.324	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.676	0.324	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.676	0.324	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.676	0.324	0.000
Y48 Anaesthetics and therapeutic gases	0.676	0.324	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.676	0.324	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.676	0.324	0.000
M66.0 Rupture of popliteal cyst	0.675	0.324	0.000
S20-S29 Injuries to the thorax	0.675	0.325	0.000
S00.9 Superficial injury of head, part unspecified	0.674	0.325	0.000
A07 Other protozoal intestinal diseases	0.674	0.326	0.000
A06 Amoebiasis	0.674	0.326	0.000
A05 Other bacterial foodborne intoxications	0.674	0.326	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations