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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117873316
log Bayes Factor = 14.6834
Chromosome 8   position 135,652,254  (GRCh37) Explore rs117873316 on Ensembl!
Variant rs117873316 is part of Cluster X0156

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
0.997 0.003 0.000
K55-K64 Other diseases of intestines
0.995 0.005 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.995 0.005 0.000
Chapter XIV Diseases of the genitourinary system
0.994 0.006 0.000
Chapter X Diseases of the respiratory system
0.994 0.006 0.000
Chapter I Certain infectious and parasitic diseases
0.992 0.008 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.992 0.008 0.000
Chapter VII Diseases of the eye and adnexa
0.990 0.010 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.989 0.011 0.000
Chapter XXI Factors influencing health status and contact with health services
0.989 0.011 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.982 0.018 0.000
J40-J47 Chronic lower respiratory diseases
0.976 0.024 0.000
N81 Female genital prolapse
0.976 0.024 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.975 0.025 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.968 0.032 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.963 0.037 0.000
Y43 Primarily systemic agents
0.958 0.042 0.000
B95-B98 Bacterial, viral and other infectious agents
0.958 0.042 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.957 0.043 0.000
Chapter VI Diseases of the nervous system
0.957 0.043 0.000
J44 Other chronic obstructive pulmonary disease
0.955 0.045 0.000
H40-H42 Glaucoma
0.953 0.047 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.951 0.049 0.000
J00-J06 Acute upper respiratory infections
0.947 0.053 0.000
K57 Diverticular disease of intestine
0.945 0.055 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.945 0.055 0.000
K61 Abscess of anal and rectal regions
0.938 0.062 0.000
Y43.3 Other antineoplastic drugs
0.934 0.066 0.000
N94.6 Dysmenorrhoea, unspecified
0.930 0.070 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.928 0.072 0.000
H40 Glaucoma
0.926 0.074 0.000
W20-W49 Exposure to inanimate mechanical forces
0.924 0.076 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.921 0.079 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.920 0.080 0.000
K58 Irritable bowel syndrome
0.917 0.083 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.910 0.090 0.000
H30-H36 Disorders of choroid and retina
0.902 0.098 0.000
M50-M54 Other dorsopathies
0.901 0.099 0.000
K60 Fissure and fistula of anal and rectal regions
0.900 0.100 0.000
N81.6 Rectocele
0.899 0.101 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.898 0.102 0.000
Z87 Personal history of other diseases and conditions
0.897 0.103 0.000
N81.1 Cystocele
0.894 0.106 0.000
Z80 Family history of malignant neoplasm
0.893 0.107 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.893 0.107 0.000
R06 Abnormalities of breathing
0.891 0.109 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.885 0.115 0.000
A00-A09 Intestinal infectious diseases
0.884 0.116 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.883 0.117 0.000
W00-W19 Falls
0.881 0.119 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.877 0.123 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.870 0.130 0.000
N81.5 Vaginal enterocele
0.868 0.132 0.000
N10-N16 Renal tubulo-interstitial diseases
0.868 0.132 0.000
K58.9 Irritable bowel syndrome without diarrhoea
0.863 0.137 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.862 0.138 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.860 0.140 0.000
Z96 Presence of other functional implants
0.857 0.143 0.000
Chapter V Mental and behavioural disorders
0.854 0.146 0.000
Z60 Problems related to social environment
0.853 0.147 0.000
R07 Pain in throat and chest
0.852 0.148 0.000
H35 Other retinal disorders
0.850 0.150 0.000
R05 Cough
0.849 0.151 0.000
H40.1 Primary open-angle glaucoma
0.849 0.151 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.846 0.154 0.000
K61.3 Ischiorectal abscess
0.845 0.155 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.843 0.157 0.000
G40-G47 Episodic and paroxysmal disorders
0.843 0.157 0.000
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess
0.841 0.159 0.000
K60.1 Chronic anal fissure
0.840 0.160 0.000
J02 Acute pharyngitis
0.838 0.162 0.000
N89 Other noninflammatory disorders of vagina
0.838 0.162 0.000
R06.0 Dyspnoea
0.837 0.163 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.835 0.165 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.834 0.166 0.000
H43-H45 Disorders of vitreous body and globe
0.833 0.167 0.000
K59 Other functional intestinal disorders
0.832 0.168 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.832 0.168 0.000
M54 Dorsalgia
0.831 0.169 0.000
G90-G99 Other disorders of the nervous system
0.830 0.170 0.000
E65-E68 Obesity and other hyperalimentation
0.828 0.172 0.000
M51 Other intervertebral disk disorders
0.827 0.173 0.000
W25 Contact with sharp glass
0.826 0.174 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.825 0.175 0.000
H40.9 Glaucoma, unspecified
0.825 0.175 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.824 0.176 0.000
Z87.1 Personal history of diseases of the digestive system
0.824 0.176 0.000
K61.0 Anal abscess
0.820 0.180 0.000
J45 Asthma
0.820 0.180 0.000
K40-K46 Hernia
0.820 0.180 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.819 0.181 0.000
N60-N64 Disorders of breast
0.819 0.181 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.819 0.181 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.813 0.187 0.000
Z60.2 Living alone
0.813 0.187 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.812 0.188 0.000
Chapter VIII Diseases of the ear and mastoid process
0.806 0.194 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.805 0.195 0.000
N13 Obstructive and reflux uropathy
0.804 0.196 0.000
N85.0 Endometrial glandular hyperplasia
0.803 0.197 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.803 0.197 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.802 0.198 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.802 0.198 0.000
J03 Acute tonsillitis
0.801 0.199 0.000
R04 Haemorrhage from respiratory passages
0.799 0.201 0.000
Z80.0 Family history of malignant neoplasm of digestive organs
0.799 0.201 0.000
E66 Obesity
0.799 0.201 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.798 0.201 0.000
K57.3 Diverticular disease of large intestine without perforation or abscess
0.798 0.202 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.797 0.203 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.797 0.203 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.796 0.204 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.795 0.205 0.000
Y83.3 Surgical operation with formation of external stoma
0.792 0.208 0.000
Y83.8 Other surgical procedures
0.791 0.209 0.000
A30-A49 Other bacterial diseases
0.790 0.210 0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue
0.789 0.211 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.788 0.212 0.000
K81 Cholecystitis
0.788 0.212 0.000
N30-N39 Other diseases of urinary system
0.787 0.213 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.786 0.214 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.785 0.215 0.000
J00 Acute nasopharyngitis [common cold]
0.784 0.216 0.000
S40-S49 Injuries to the shoulder and upper arm
0.782 0.218 0.000
N80 Endometriosis
0.781 0.219 0.000
K50-K52 Noninfective enteritis and colitis
0.780 0.220 0.000
K42 Umbilical hernia
0.779 0.221 0.000
Z87.0 Personal history of diseases of the respiratory system
0.777 0.223 0.000
N94.3 Premenstrual tension syndrome
0.776 0.224 0.000
S90-S99 Injuries to the ankle and foot
0.776 0.224 0.000
R06.8 Other and unspecified abnormalities of breathing
0.776 0.224 0.000
N81.3 Complete uterovaginal prolapse
0.774 0.226 0.000
H25-H28 Disorders of lens
0.773 0.227 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.773 0.227 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.773 0.227 0.000
Y52 Agents primarily affecting the cardiovascular system
0.772 0.228 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.772 0.228 0.000
J30-J39 Other diseases of upper respiratory tract
0.772 0.228 0.000
Z93 Artificial opening status
0.771 0.229 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.771 0.229 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.771 0.229 0.000
M80-M85 Disorders of bone density and structure
0.770 0.230 0.000
N97 Female infertility
0.770 0.230 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.768 0.232 0.000
T66-T78 Other and unspecified effects of external causes
0.768 0.232 0.000
G20-G26 Extrapyramidal and movement disorders
0.767 0.233 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.766 0.234 0.000
W22 Striking against or struck by other objects
0.764 0.236 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.764 0.236 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.763 0.237 0.000
M54.9 Dorsalgia, unspecified
0.763 0.237 0.000
Y57 Other and unspecified drugs and medicaments
0.762 0.238 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.762 0.238 0.000
A04 Other bacterial intestinal infections
0.761 0.239 0.000
J02.9 Acute pharyngitis, unspecified
0.760 0.240 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.759 0.241 0.000
Z88.2 Personal history of allergy to sulphonamides
0.759 0.241 0.000
J43 Emphysema
0.759 0.241 0.000
H35.4 Peripheral retinal degeneration
0.759 0.241 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.758 0.242 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.758 0.242 0.000
S00-S09 Injuries to the head
0.758 0.242 0.000
N64 Other disorders of breast
0.757 0.243 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.757 0.243 0.000
W25.9 Unspecified place
0.756 0.244 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.756 0.244 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.755 0.245 0.000
K57.2 Diverticular disease of large intestine with perforation and abscess
0.755 0.245 0.000
S70-S79 Injuries to the hip and thigh
0.754 0.245 0.000
H40.2 Primary angle-closure glaucoma
0.754 0.246 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.754 0.246 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.753 0.247 0.000
E66.9 Obesity, unspecified
0.752 0.248 0.000
J09-J18 Influenza and pneumonia
0.752 0.248 0.000
Y83.4 Other reconstructive surgery
0.751 0.249 0.000
R20 Disturbances of skin sensation
0.751 0.249 0.000
B15-B19 Viral hepatitis
0.750 0.249 0.000
K42.9 Umbilical hernia without obstruction or gangrene
0.750 0.250 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.749 0.251 0.000
V10-V19 Pedal cyclist injured in transport accident
0.749 0.251 0.000
S80-S89 Injuries to the knee and lower leg
0.748 0.252 0.000
J46 Status asthmaticus
0.747 0.253 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.746 0.254 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.746 0.254 0.000
B35-B49 Mycoses
0.745 0.255 0.000
N85.9 Noninflammatory disorder of uterus, unspecified
0.743 0.257 0.000
Y83.6 Removal of other organ (partial) (total)
0.743 0.257 0.000
K56.2 Volvulus
0.742 0.258 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.740 0.259 0.000
R07.4 Chest pain, unspecified
0.739 0.261 0.000
K55 Vascular disorders of intestine
0.739 0.261 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.738 0.262 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.738 0.262 0.000
H10-H13 Disorders of conjunctiva
0.738 0.262 0.000
X60-X84 Intentional self-harm
0.737 0.263 0.000
Z80.8 Family history of malignant neoplasm of other organs or systems
0.737 0.263 0.000
Z04 Examination and observation for other reasons
0.736 0.264 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.736 0.264 0.000
N88 Other noninflammatory disorders of cervix uteri
0.736 0.264 0.000
M51.2 Other specified intervertebral disk displacement
0.735 0.265 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.734 0.266 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.733 0.267 0.000
Z96.6 Presence of orthopaedic joint implants
0.731 0.269 0.000
J45.0 Predominantly allergic asthma
0.730 0.270 0.000
N89.8 Other specified noninflammatory disorders of vagina
0.729 0.271 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.729 0.271 0.000
Y40 Systemic antibiotics
0.726 0.274 0.000
Z83 Family history of other specific disorders
0.726 0.274 0.000
N81.8 Other female genital prolapse
0.726 0.274 0.000
Z97 Presence of other devices
0.725 0.274 0.000
B25-B34 Other viral diseases
0.725 0.275 0.000
R21 Rash and other nonspecific skin eruption
0.724 0.276 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.724 0.276 0.000
H55-H59 Other disorders of eye and adnexa
0.723 0.277 0.000
G93 Other disorders of brain
0.723 0.277 0.000
M86-M90 Other osteopathies
0.722 0.278 0.000
N92 Excessive, frequent and irregular menstruation
0.721 0.279 0.000
Z96.7 Presence of other bone and tendon implants
0.721 0.279 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.720 0.280 0.000
S20-S29 Injuries to the thorax
0.719 0.281 0.000
H33 Retinal detachments and breaks
0.717 0.282 0.000
Chapter XXII Codes for special purposes
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.717 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.717 0.283 0.000
Y10-Y34 Event of undetermined intent
0.717 0.283 0.000
Y00-Y09 Assault
0.717 0.283 0.000
X85-X99 Assault
0.717 0.283 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.717 0.283 0.000
X50-X57 Overexertion, travel and privation
0.717 0.283 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.717 0.283 0.000
X30-X39 Exposure to forces of nature
0.717 0.283 0.000
X20-X29 Contact with venomous animals and plants
0.717 0.283 0.000
X10-X19 Contact with heat and hot substances
0.717 0.283 0.000
X00-X09 Exposure to smoke, fire and flames
0.717 0.283 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.717 0.283 0.000
W75-W84 Other accidental threats to breathing
0.717 0.283 0.000
W65-W74 Accidental drowning and submersion
0.717 0.283 0.000
W50-W64 Exposure to animate mechanical forces
0.717 0.283 0.000
V98-V99 Other and unspecified transport accidents
0.717 0.283 0.000
V95-V97 Air and space transport accidents
0.717 0.283 0.000
V90-V94 Water transport accidents
0.717 0.283 0.000
V80-V89 Other land transport accidents
0.717 0.283 0.000
V70-V79 Bus occupant injured in transport accident
0.717 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.717 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.717 0.283 0.000
V40-V49 Car occupant injured in transport accident
0.717 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.717 0.283 0.000
V20-V29 Motorcycle rider injured in transport accident
0.717 0.283 0.000
V01-V09 Pedestrian injured in transport accident
0.717 0.283 0.000
W19 Unspecified fall
0.715 0.285 0.000
J40 Bronchitis, not specified as acute or chronic
0.714 0.286 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.714 0.286 0.000
T79-T79 Certain early complications of trauma
0.713 0.286 0.000
T33-T35 Frostbite
0.713 0.286 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.713 0.286 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.713 0.286 0.000
T00-T07 Injuries involving multiple body regions
0.713 0.286 0.000
S10-S19 Injuries to the neck
0.713 0.286 0.000
N85.4 Malposition of uterus
0.713 0.287 0.000
K57.1 Diverticular disease of small intestine without perforation or abscess
0.713 0.287 0.000
K81.1 Chronic cholecystitis
0.713 0.287 0.000
R47-R49 Symptoms and signs involving speech and voice
0.713 0.287 0.000
N17-N19 Renal failure
0.712 0.288 0.000
Z94 Transplanted organ and tissue status
0.712 0.288 0.000
B99-B99 Other infectious diseases
0.712 0.288 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.712 0.288 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.712 0.288 0.000
B65-B83 Helminthiases
0.712 0.288 0.000
B50-B64 Protozoal diseases
0.712 0.288 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.712 0.288 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.712 0.288 0.000
A80-A89 Viral infections of the central nervous system
0.712 0.288 0.000
A75-A79 Rickettsioses
0.712 0.288 0.000
A70-A74 Other diseases caused by chlamydiae
0.712 0.288 0.000
A65-A69 Other spirochaetal diseases
0.712 0.288 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.712 0.288 0.000
A20-A28 Certain zoonotic bacterial diseases
0.712 0.288 0.000
A15-A19 Tuberculosis
0.712 0.288 0.000
Y59 Other and unspecified vaccines and biological substances
0.711 0.288 0.000
Y58 Bacterial vaccines
0.711 0.288 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.711 0.288 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.711 0.288 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.711 0.288 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.711 0.288 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.711 0.288 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.711 0.288 0.000
Y48 Anaesthetics and therapeutic gases
0.711 0.288 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.711 0.288 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.711 0.288 0.000
Y44 Agents primarily affecting blood constituents
0.711 0.288 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.711 0.288 0.000
Z80.9 Family history of malignant neoplasm, unspecified
0.711 0.289 0.000
D70 Agranulocytosis
0.711 0.289 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.710 0.290 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.710 0.290 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.710 0.290 0.000
N98 Complications associated with artificial fertilisation
0.709 0.291 0.000
N91 Absent, scanty and rare menstruation
0.709 0.291 0.000
N82 Fistulae involving female genital tract
0.709 0.291 0.000
N96 Habitual aborter
0.709 0.291 0.000
R04.2 Haemoptysis
0.707 0.293 0.000
G70-G73 Diseases of myoneural junction and muscle
0.706 0.294 0.000
Z30 Contraceptive management
0.704 0.296 0.000
N25-N29 Other disorders of kidney and ureter
0.704 0.296 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.704 0.296 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.704 0.296 0.000
N75 Diseases of Bartholin's gland
0.703 0.297 0.000
K85 Acute pancreatitis
0.703 0.297 0.000
H35.3 Degeneration of macula and posterior pole
0.702 0.297 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.702 0.298 0.000
N00-N08 Glomerular diseases
0.701 0.299 0.000
J41 Simple and mucopurulent chronic bronchitis
0.700 0.300 0.000
J42 Unspecified chronic bronchitis
0.700 0.300 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.700 0.300 0.000
N81.9 Female genital prolapse, unspecified
0.699 0.300 0.000
N81.0 Female urethrocele
0.699 0.300 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.698 0.302 0.000
Z36 Antenatal screening
0.698 0.302 0.000
E50-E64 Other nutritional deficiencies
0.698 0.302 0.000
W08 Fall involving other furniture
0.697 0.303 0.000
K65-K67 Diseases of peritoneum
0.697 0.303 0.000
H44 Disorders of globe
0.697 0.303 0.000
A04.8 Other specified bacterial intestinal infections
0.697 0.303 0.000
K50 Crohn's disease [regional enteritis]
0.697 0.303 0.000
J03.9 Acute tonsillitis, unspecified
0.696 0.304 0.000
E66.8 Other obesity
0.695 0.305 0.000
T87 Complications peculiar to reattachment and amputation
0.694 0.306 0.000
T86 Failure and rejection of transplanted organs and tissues
0.694 0.306 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.694 0.306 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.694 0.306 0.000
Y42.5 Other oestrogens and progestogens
0.693 0.307 0.000
R06.4 Hyperventilation
0.693 0.307 0.000
Z87.2 Personal history of diseases of the skin and subcutaneous tissue
0.692 0.308 0.000
Z01.6 Radiological examination, not elsewhere classified
0.692 0.308 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.691 0.309 0.000
K60.2 Anal fissure, unspecified
0.691 0.309 0.000
Y43.9 Primarily systemic agent, unspecified
0.687 0.313 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.687 0.313 0.000
Y43.6 Enzymes, not elsewhere classified
0.687 0.313 0.000
Y43.5 Acidifying and alkalising agents
0.687 0.313 0.000
Y43.4 Immunosuppressive agents
0.687 0.313 0.000
Y43.2 Antineoplastic natural products
0.687 0.313 0.000
Y43.1 Antineoplastic antimetabolites
0.687 0.313 0.000
Y43.0 Antiallergic and antiemetic drugs
0.687 0.313 0.000
R41.0 Disorientation, unspecified
0.687 0.313 0.000
Z80.5 Family history of malignant neoplasm of urinary tract
0.687 0.313 0.000
M51.8 Other specified intervertebral disk disorders
0.687 0.313 0.000
N94.9 Unspecified condition associated with female genital organs and menstrual cycle
0.686 0.313 0.000
N94.5 Secondary dysmenorrhoea
0.686 0.313 0.000
N94.4 Primary dysmenorrhoea
0.686 0.313 0.000
N94.2 Vaginismus
0.686 0.313 0.000
N94.0 Mittelschmerz
0.686 0.313 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.686 0.313 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.686 0.313 0.000
K56.6 Other and unspecified intestinal obstruction
0.686 0.314 0.000
K59.0 Constipation
0.686 0.314 0.000
G43 Migraine
0.685 0.315 0.000
W29 Contact with other powered hand tools and household machinery
0.684 0.316 0.000
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium
0.684 0.316 0.000
G47 Sleep disorders
0.683 0.317 0.000
H42 Glaucoma in diseases classified elsewhere
0.683 0.317 0.000
N81.4 Uterovaginal prolapse, unspecified
0.682 0.317 0.000
Z93.2 Ileostomy status
0.682 0.318 0.000
Z89 Acquired absence of limb
0.682 0.318 0.000
Z84 Family history of other conditions
0.682 0.318 0.000
Z81 Family history of mental and behavioural disorders
0.682 0.318 0.000
N10 Acute tubulo-interstitial nephritis
0.681 0.319 0.000
B97.8 Other viral agents as the cause of diseases classified to other chapters
0.681 0.319 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.680 0.320 0.000
D50-D53 Nutritional anaemias
0.680 0.320 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.679 0.320 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.679 0.321 0.000
J04 Acute laryngitis and tracheitis
0.679 0.321 0.000
J01 Acute sinusitis
0.679 0.321 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.679 0.321 0.000
R22.4 Localised swelling, mass and lump, lower limb
0.679 0.321 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.678 0.322 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.678 0.322 0.000
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess
0.678 0.322 0.000
K57.5 Diverticular disease of both small and large intestine without perforation or abscess
0.678 0.322 0.000
K57.4 Diverticular disease of both small and large intestine with perforation and abscess
0.678 0.322 0.000
K57.0 Diverticular disease of small intestine with perforation and abscess
0.678 0.322 0.000
Y83.5 Amputation of limb(s)
0.678 0.322 0.000
Y83.0 Surgical operation with transplant of whole organ
0.678 0.322 0.000
W07 Fall involving chair
0.678 0.322 0.000
H60-H62 Diseases of external ear
0.678 0.322 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.677 0.322 0.000
N39 Other disorders of urinary system
0.677 0.323 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.676 0.324 0.000
J30 Vasomotor and allergic rhinitis
0.676 0.324 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.675 0.325 0.000
K70-K77 Diseases of liver
0.674 0.326 0.000
G30-G32 Other degenerative diseases of the nervous system
0.673 0.326 0.000
R22.2 Localised swelling, mass and lump, trunk
0.673 0.327 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.673 0.327 0.000
K61.4 Intrasphincteric abscess
0.672 0.327 0.000
K61.2 Anorectal abscess
0.672 0.327 0.000
K61.1 Rectal abscess
0.672 0.327 0.000
Y83.9 Surgical procedure, unspecified
0.672 0.328 0.000
Z98 Other postsurgical states
0.672 0.328 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.671 0.329 0.000
W06 Fall involving bed
0.671 0.329 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.670 0.330 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.668 0.332 0.000
N99-N99 Other disorders of the genitourinary system
0.667 0.333 0.000
N94.1 Dyspareunia
0.667 0.333 0.000
H40.0 Glaucoma suspect
0.667 0.333 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.666 0.334 0.000
M91-M94 Chondropathies
0.665 0.334 0.000
M60-M63 Disorders of muscles
0.665 0.334 0.000
M00-M03 Infectious arthropathies
0.665 0.334 0.000
H35.8 Other specified retinal disorders
0.665 0.334 0.000
M40-M43 Deforming dorsopathies
0.665 0.335 0.000
K82 Other diseases of gallbladder
0.665 0.335 0.000
R22.0 Localised swelling, mass and lump, head
0.664 0.336 0.000
H40.8 Other glaucoma
0.664 0.336 0.000
H40.6 Glaucoma secondary to drugs
0.664 0.336 0.000
H40.5 Glaucoma secondary to other eye disorders
0.664 0.336 0.000
H40.4 Glaucoma secondary to eye inflammation
0.664 0.336 0.000
H40.3 Glaucoma secondary to eye trauma
0.664 0.336 0.000
M50 Cervical disk disorders
0.664 0.336 0.000
S50-S59 Injuries to the elbow and forearm
0.663 0.337 0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
0.663 0.337 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.662 0.337 0.000
M54.3 Sciatica
0.662 0.338 0.000
W49 Exposure to other and unspecified inanimate mechanical forces
0.662 0.338 0.000
W46 Contact with hypodermic needle
0.662 0.338 0.000
W45 Foreign body or object entering through skin
0.662 0.338 0.000
W44 Foreign body entering into or through eye or natural orifice
0.662 0.338 0.000
W43 Exposure to vibration
0.662 0.338 0.000
W42 Exposure to noise
0.662 0.338 0.000
W41 Exposure to high-pressure jet
0.662 0.338 0.000
W40 Explosion of other materials
0.662 0.338 0.000
W39 Discharge of firework
0.662 0.338 0.000
W38 Explosion and rupture of other specified pressurised devices
0.662 0.338 0.000
W37 Explosion and rupture of pressurised tyre, pipe or hose
0.662 0.338 0.000
W36 Explosion and rupture of gas cylinder
0.662 0.338 0.000
W35 Explosion and rupture of boiler
0.662 0.338 0.000
W34 Discharge from other and unspecified firearms
0.662 0.338 0.000
W33 Rifle, shotgun and larger firearm discharge
0.662 0.338 0.000
W32 Handgun discharge
0.662 0.338 0.000
W31 Contact with other and unspecified machinery
0.662 0.338 0.000
W30 Contact with agricultural machinery
0.662 0.338 0.000
W28 Contact with powered lawn mower
0.662 0.338 0.000
W27 Contact with nonpowered hand tool
0.662 0.338 0.000
W26 Contact with knife, sword or dagger
0.662 0.338 0.000
W24 Contact with lifting and transmission devices, not elsewhere classified
0.662 0.338 0.000
W23 Caught, crushed, jammed or pinched in or between objects
0.662 0.338 0.000
W21 Striking against or struck by sports equipment
0.662 0.338 0.000
W20 Struck by thrown, projected or falling object
0.662 0.338 0.000
K35-K38 Diseases of appendix
0.662 0.338 0.000
M20-M25 Other joint disorders
0.661 0.339 0.000
G44 Other headache syndromes
0.661 0.339 0.000
R23 Other skin changes
0.660 0.340 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.660 0.340 0.000
Z29 Need for other prophylactic measures
0.659 0.341 0.000
H25 Senile cataract
0.659 0.341 0.000
R26 Abnormalities of gait and mobility
0.659 0.341 0.000
Z96.8 Presence of other specified functional implants
0.659 0.341 0.000
R07.2 Precordial pain
0.658 0.342 0.000
N86 Erosion and ectropion of cervix uteri
0.657 0.343 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.656 0.344 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.654 0.346 0.000
N13.3 Other and unspecified hydronephrosis
0.654 0.346 0.000
Z04.8 Examination and observation for other specified reasons
0.653 0.347 0.000
Z65 Problems related to other psychosocial circumstances
0.652 0.347 0.000
Z64 Problems related to certain psychosocial circumstances
0.652 0.347 0.000
Z63 Other problems related to primary support group, including family circumstances
0.652 0.347 0.000
Z62 Other problems related to upbringing
0.652 0.347 0.000
Z61 Problems related to negative life events in childhood
0.652 0.347 0.000
Z59 Problems related to housing and economic circumstances
0.652 0.347 0.000
Z58 Problems related to physical environment
0.652 0.347 0.000
Z57 Occupational exposure to risk-factors
0.652 0.347 0.000
Z56 Problems related to employment and unemployment
0.652 0.347 0.000
Z55 Problems related to education and literacy
0.652 0.347 0.000
K58.0 Irritable bowel syndrome with diarrhoea
0.652 0.348 0.000
N64.5 Other signs and symptoms in breast
0.652 0.348 0.000
Z12 Special screening examination for neoplasms
0.651 0.349 0.000
W22.9 Unspecified place
0.650 0.350 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.650 0.350 0.000
R02 Gangrene, not elsewhere classified
0.650 0.350 0.000
R22.9 Localised swelling, mass and lump, unspecified
0.649 0.351 0.000
R25 Abnormal involuntary movements
0.649 0.351 0.000
Y42.7 Androgens and anabolic congeners
0.649 0.351 0.000
J60-J70 Lung diseases due to external agents
0.649 0.351 0.000
R01 Cardiac murmurs and other cardiac sounds
0.649 0.351 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.648 0.352 0.000
R09.0 Asphyxia
0.648 0.352 0.000
T81 Complications of procedures, not elsewhere classified
0.647 0.353 0.000
J36 Peritonsillar abscess
0.647 0.353 0.000
K43 Ventral hernia
0.647 0.353 0.000
H34 Retinal vascular occlusions
0.647 0.353 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.647 0.353 0.000
H31 Other disorders of choroid
0.647 0.353 0.000
H30 Chorioretinal inflammation
0.647 0.353 0.000
M53 Other dorsopathies, not elsewhere classified
0.646 0.354 0.000
J20-J22 Other acute lower respiratory infections
0.646 0.354 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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