TreeWAS – Variant ID: rs75059066

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter XX External causes of morbidity and mortality	0.999	0.001
Chapter X Diseases of the respiratory system	0.999	0.001
J33 Nasal polyp	0.999	0.001
J30-J39 Other diseases of upper respiratory tract	0.998	0.002
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.997	0.003
Chapter I Certain infectious and parasitic diseases	0.995	0.005
Chapter V Mental and behavioural disorders	0.994	0.006
B95-B98 Bacterial, viral and other infectious agents	0.993	0.007
J33.9 Nasal polyp, unspecified	0.993	0.007
Chapter IX Diseases of the circulatory system	0.993	0.007
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.991	0.009
J33.8 Other polyp of sinus	0.987	0.013
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.985	0.015
I60-I69 Cerebrovascular diseases	0.982	0.018
I27 Other pulmonary heart diseases	0.981	0.019
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.968	0.032
D60-D64 Aplastic and other anaemias	0.968	0.032
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.958	0.042
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.955	0.045
W20-W49 Exposure to inanimate mechanical forces	0.954	0.046
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.952	0.048
I69 Sequelae of cerebrovascular disease	0.951	0.049
F00-F09 Organic, including symptomatic, mental disorders	0.949	0.051
T36-T50 Poisoning by drugs, medicaments and biological substances	0.948	0.052
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.945	0.055
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.945	0.055
I27.9 Pulmonary heart disease, unspecified	0.942	0.058
D64 Other anaemias	0.934	0.066
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.932	0.068
Y95 Nosocomial condition	0.923	0.077
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.921	0.079
J80-J84 Other respiratory diseases principally affecting the interstitium	0.919	0.081
Q20-Q28 Congenital malformations of the circulatory system	0.918	0.082
J34 Other disorders of nose and nasal sinuses	0.917	0.083
I27.2 Other secondary pulmonary hypertension	0.917	0.083
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.916	0.084
J09-J18 Influenza and pneumonia	0.915	0.085
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.914	0.086
D55-D59 Haemolytic anaemias	0.913	0.087
J34.8 Other specified disorders of nose and nasal sinuses	0.911	0.089
D64.9 Anaemia, unspecified	0.909	0.091
I63 Cerebral infarction	0.908	0.092
T84.0 Mechanical complication of internal joint prosthesis	0.898	0.102
T66-T78 Other and unspecified effects of external causes	0.895	0.105
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters	0.895	0.105
T50.9 Other and unspecified drugs, medicaments and biological substances	0.893	0.107
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters	0.892	0.108
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.892	0.108
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.883	0.117
Y40 Systemic antibiotics	0.883	0.117
D63 Anaemia in chronic diseases classified elsewhere	0.881	0.119
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.881	0.119
I69.3 Sequelae of cerebral infarction	0.877	0.123
T81 Complications of procedures, not elsewhere classified	0.876	0.124
F05 Delirium, not induced by alcohol and other psychoactive substances	0.876	0.124
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters	0.872	0.128
F40-F48 Neurotic, stress-related and somatoform disorders	0.871	0.129
A65-A69 Other spirochaetal diseases	0.870	0.130
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters	0.861	0.139
J33.0 Polyp of nasal cavity	0.860	0.140
I27.0 Primary pulmonary hypertension	0.860	0.140
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters	0.859	0.141
D69 Purpura and other haemorrhagic conditions	0.857	0.143
T81.3 Disruption of operation wound, not elsewhere classified	0.843	0.157
F99-F99 Unspecified mental disorder	0.839	0.161
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.838	0.162
S70-S79 Injuries to the hip and thigh	0.837	0.163
Q60-Q64 Congenital malformations of the urinary system	0.832	0.168
I60 Subarachnoid haemorrhage	0.832	0.168
V40-V49 Car occupant injured in transport accident	0.830	0.170
Q23 Congenital malformations of aortic and mitral valves	0.830	0.170
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.829	0.171
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.827	0.173
W29 Contact with other powered hand tools and household machinery	0.827	0.173
D80-D89 Certain disorders involving the immune mechanism	0.827	0.173
I61 Intracerebral haemorrhage	0.826	0.174
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.825	0.175
F05.9 Delirium, unspecified	0.825	0.175
X58-X59 Accidental exposure to other and unspecified factors	0.824	0.176
F45 Somatoform disorders	0.822	0.178
D50-D53 Nutritional anaemias	0.820	0.180
F30-F39 Mood [affective] disorders	0.816	0.184
D69.3 Idiopathic thrombocytopenic purpura	0.814	0.186
I05-I09 Chronic rheumatic heart diseases	0.814	0.186
W00-W19 Falls	0.814	0.186
I69.1 Sequelae of intracerebral haemorrhage	0.812	0.188
Chapter XV Pregnancy, childbirth and the puerperium	0.810	0.190
Y44 Agents primarily affecting blood constituents	0.798	0.202
Q21 Congenital malformations of cardiac septa	0.798	0.202
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.797	0.203
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.797	0.203
T20-T25 Burns and corrosions of external body surface, specified by site	0.796	0.204
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters	0.794	0.206
D58 Other hereditary haemolytic anaemias	0.793	0.207
T83.0 Mechanical complication of urinary (indwelling) catheter	0.793	0.207
X60-X84 Intentional self-harm	0.792	0.208
F02 Dementia in other diseases classified elsewhere	0.792	0.208
O20-O29 Other maternal disorders predominantly related to pregnancy	0.789	0.211
V01-V09 Pedestrian injured in transport accident	0.788	0.212
F23 Acute and transient psychotic disorders	0.788	0.212
I27.8 Other specified pulmonary heart diseases	0.787	0.213
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.787	0.213
Y57 Other and unspecified drugs and medicaments	0.786	0.214
T68 Hypothermia	0.785	0.215
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.784	0.216
W50-W64 Exposure to animate mechanical forces	0.782	0.218
A69 Other spirochaetal infections	0.781	0.219
J15 Bacterial pneumonia, not elsewhere classified	0.781	0.219
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.777	0.223
D63.0 Anaemia in neoplastic disease	0.777	0.223
I69.0 Sequelae of subarachnoid haemorrhage	0.777	0.223
B50-B64 Protozoal diseases	0.776	0.224
W25 Contact with sharp glass	0.774	0.226
J82 Pulmonary eosinophilia, not elsewhere classified	0.772	0.228
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.771	0.229
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.770	0.230
F45.8 Other somatoform disorders	0.770	0.230
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.769	0.231
W75-W84 Other accidental threats to breathing	0.766	0.234
Y60-Y69 Misadventures to patients during surgical and medical care	0.766	0.234
J14 Pneumonia due to Haemophilus influenzae	0.765	0.235
Q23.1 Congenital insufficiency of aortic valve	0.764	0.236
Q61 Cystic kidney disease	0.763	0.237
F25 Schizoaffective disorders	0.763	0.237
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.763	0.237
W18 Other fall on same level	0.763	0.237
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.763	0.237
O20 Haemorrhage in early pregnancy	0.762	0.238
W27 Contact with nonpowered hand tool	0.762	0.238
I70-I79 Diseases of arteries, arterioles and capillaries	0.761	0.239
D59 Acquired haemolytic anaemia	0.759	0.241
J80 Adult respiratory distress syndrome	0.757	0.243
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.756	0.243
T84.1 Mechanical complication of internal fixation device of bones of limb	0.756	0.244
T78 Adverse effects, not elsewhere classified	0.755	0.245
I61.5 Intracerebral haemorrhage, intraventricular	0.750	0.250
I08 Multiple valve diseases	0.745	0.255
T36 Poisoning by systemic antibiotics	0.743	0.256
T81.9 Unspecified complication of procedure	0.743	0.257
D51 Vitamin B12 deficiency anaemia	0.743	0.257
Y53 Agents primarily affecting the gastro-intestinal system	0.743	0.257
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.742	0.258
B65-B83 Helminthiases	0.742	0.258
J90-J94 Other diseases of pleura	0.740	0.260
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.740	0.260
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.739	0.261
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.738	0.262
Y40.1 Cefalosporins and other -lactam antibiotics	0.737	0.263
Y40.8 Other systemic antibiotics	0.736	0.264
W29.9 Unspecified place	0.735	0.264
W49 Exposure to other and unspecified inanimate mechanical forces	0.735	0.265
B90-B94 Sequelae of infectious and parasitic diseases	0.735	0.265
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.734	0.266
D63.8 Anaemia in other chronic diseases classified elsewhere	0.734	0.266
A50-A64 Infections with a predominantly sexual mode of transmission	0.731	0.269
O00-O08 Pregnancy with abortive outcome	0.729	0.271
S70 Superficial injury of hip and thigh	0.729	0.271
Q21.1 Atrial septal defect	0.729	0.271
F99 Mental disorder, not otherwise specified	0.728	0.272
Q27 Other congenital malformations of peripheral vascular system	0.728	0.272
F60-F69 Disorders of adult personality and behaviour	0.727	0.273
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.726	0.274
I10-I15 Hypertensive diseases	0.725	0.275
W20 Struck by thrown, projected or falling object	0.724	0.276
T88 Other complications of surgical and medical care, not elsewhere classified	0.723	0.277
J81 Pulmonary oedema	0.720	0.280
F70-F79 Mental retardation	0.719	0.280
F23.9 Acute and transient psychotic disorder, unspecified	0.719	0.281
A00-A09 Intestinal infectious diseases	0.718	0.282
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.718	0.282
F03 Unspecified dementia	0.718	0.282
J13 Pneumonia due to Streptococcus pneumoniae	0.717	0.282
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
A69.9 Spirochaetal infection, unspecified	0.717	0.283
O20.0 Threatened abortion	0.716	0.284
Y35-Y36 Legal intervention and operations of war	0.716	0.284
Y10-Y34 Event of undetermined intent	0.716	0.284
X85-X99 Assault	0.716	0.284
X30-X39 Exposure to forces of nature	0.716	0.284
X10-X19 Contact with heat and hot substances	0.716	0.284
X00-X09 Exposure to smoke, fire and flames	0.716	0.284
W65-W74 Accidental drowning and submersion	0.716	0.284
V98-V99 Other and unspecified transport accidents	0.716	0.284
V95-V97 Air and space transport accidents	0.716	0.284
V90-V94 Water transport accidents	0.716	0.284
V70-V79 Bus occupant injured in transport accident	0.716	0.284
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.716	0.284
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.716	0.284
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.716	0.284
J33.1 Polypoid sinus degeneration	0.716	0.284
T15-T19 Effects of foreign body entering through natural orifice	0.715	0.285
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.715	0.285
Q38-Q45 Other congenital malformations of the digestive system	0.714	0.286
J18 Pneumonia, organism unspecified	0.714	0.286
B85-B89 Pediculosis, acariasis and other infestations	0.713	0.287
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.713	0.287
A75-A79 Rickettsioses	0.713	0.287
A70-A74 Other diseases caused by chlamydiae	0.713	0.287
A20-A28 Certain zoonotic bacterial diseases	0.713	0.287
A15-A19 Tuberculosis	0.713	0.287
Y41 Other systemic anti-infectives and antiparasitics	0.713	0.287
V43 Car occupant injured in collision with car, pick-up truck or van	0.713	0.287
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.712	0.287
W21 Striking against or struck by sports equipment	0.712	0.288
I00-I02 Acute rheumatic fever	0.712	0.288
J36 Peritonsillar abscess	0.712	0.288
X20-X29 Contact with venomous animals and plants	0.711	0.289
I72 Other aneurysm	0.708	0.292
J84 Other interstitial pulmonary diseases	0.708	0.292
W44 Foreign body entering into or through eye or natural orifice	0.708	0.292
Y40.3 Macrolides	0.708	0.292
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.707	0.293
F32 Depressive episode	0.707	0.293
D66 Hereditary factor VIII deficiency	0.707	0.293
J60-J70 Lung diseases due to external agents	0.707	0.293
X50-X57 Overexertion, travel and privation	0.706	0.294
J12 Viral pneumonia, not elsewhere classified	0.706	0.294
I28 Other diseases of pulmonary vessels	0.706	0.294
J00-J06 Acute upper respiratory infections	0.705	0.295
D61 Other aplastic anaemias	0.705	0.295
I68 Cerebrovascular disorders in diseases classified elsewhere	0.704	0.296
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.704	0.296
I60.8 Other subarachnoid haemorrhage	0.704	0.296
D80 Immunodeficiency with predominantly antibody defects	0.704	0.296
I27.1 Kyphoscoliotic heart disease	0.703	0.296
B99-B99 Other infectious diseases	0.703	0.297
S79 Other and unspecified injuries of hip and thigh	0.703	0.297
Y40.9 Systemic antibiotic, unspecified	0.702	0.297
W22 Striking against or struck by other objects	0.702	0.298
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.702	0.298
Y00-Y09 Assault	0.700	0.300
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.699	0.301
Y52 Agents primarily affecting the cardiovascular system	0.698	0.302
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters	0.696	0.304
V20-V29 Motorcycle rider injured in transport accident	0.695	0.305
I08.0 Disorders of both mitral and aortic valves	0.695	0.305
J32 Chronic sinusitis	0.695	0.305
D56 Thalassaemia	0.694	0.306
T33-T35 Frostbite	0.694	0.306
T26-T28 Burns and corrosions confined to eye and internal organs	0.694	0.306
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.694	0.306
J15.1 Pneumonia due to Pseudomonas	0.694	0.306
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.693	0.307
Y48 Anaesthetics and therapeutic gases	0.693	0.307
T00-T07 Injuries involving multiple body regions	0.687	0.313
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.687	0.313
Q35-Q37 Cleft lip and cleft palate	0.687	0.313
Q30-Q34 Congenital malformations of the respiratory system	0.687	0.313
S10-S19 Injuries to the neck	0.686	0.314
W18.3 Sports and athletics area	0.685	0.315
W46 Contact with hypodermic needle	0.684	0.316
W45 Foreign body or object entering through skin	0.684	0.316
W43 Exposure to vibration	0.684	0.316
W42 Exposure to noise	0.684	0.316
W41 Exposure to high-pressure jet	0.684	0.316
W40 Explosion of other materials	0.684	0.316
W39 Discharge of firework	0.684	0.316
W38 Explosion and rupture of other specified pressurised devices	0.684	0.316
W37 Explosion and rupture of pressurised tyre, pipe or hose	0.684	0.316
W36 Explosion and rupture of gas cylinder	0.684	0.316
W35 Explosion and rupture of boiler	0.684	0.316
W34 Discharge from other and unspecified firearms	0.684	0.316
W33 Rifle, shotgun and larger firearm discharge	0.684	0.316
W32 Handgun discharge	0.684	0.316
W31 Contact with other and unspecified machinery	0.684	0.316
W30 Contact with agricultural machinery	0.684	0.316
W28 Contact with powered lawn mower	0.684	0.316
W26 Contact with knife, sword or dagger	0.684	0.316
W24 Contact with lifting and transmission devices, not elsewhere classified	0.684	0.316
W23 Caught, crushed, jammed or pinched in or between objects	0.684	0.316
O02 Other abnormal products of conception	0.684	0.316
J37 Chronic laryngitis and laryngotracheitis	0.684	0.316
F80-F89 Disorders of psychological development	0.683	0.317
Y90 Evidence of alcohol involvement determined by blood alcohol level	0.682	0.317
Y98 Lifestyle-related condition	0.682	0.317
Y97 Environmental-pollution-related condition	0.682	0.317
Y96 Work-related condition	0.682	0.317
F42 Obsessive-compulsive disorder	0.681	0.319
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.680	0.320
F09 Unspecified organic or symptomatic mental disorder	0.680	0.320
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.680	0.320
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.680	0.320
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.680	0.320
T41 Poisoning by anaesthetics and therapeutic gases	0.680	0.320
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.680	0.320
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.679	0.321
Y40.0 Penicillins	0.679	0.321
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters	0.678	0.322
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters	0.678	0.322
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters	0.678	0.322
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.678	0.322
B20-B24 Human immunodeficiency virus [HIV] disease	0.675	0.325
F34 Persistent mood [affective] disorders	0.675	0.325
Q24 Other congenital malformations of heart	0.674	0.326
J30 Vasomotor and allergic rhinitis	0.674	0.326
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.674	0.326
O21 Excessive vomiting in pregnancy	0.674	0.326
I95-I99 Other and unspecified disorders of the circulatory system	0.673	0.327
T83.1 Mechanical complication of other urinary devices and implants	0.672	0.328
Q61.3 Polycystic kidney, unspecified	0.671	0.329
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.671	0.329
O20.9 Haemorrhage in early pregnancy, unspecified	0.670	0.330
D64.8 Other specified anaemias	0.669	0.331
D64.4 Congenital dyserythropoietic anaemia	0.669	0.331
D64.3 Other sideroblastic anaemias	0.669	0.331
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.669	0.331
D64.1 Secondary sideroblastic anaemia due to disease	0.669	0.331
D64.0 Hereditary sideroblastic anaemia	0.669	0.331
Y59 Other and unspecified vaccines and biological substances	0.668	0.331
Y58 Bacterial vaccines	0.668	0.331
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.668	0.331
Y50 Central nervous system stimulants, not elsewhere classified	0.668	0.331
Y47 Sedatives, hypnotics and antianxiety drugs	0.668	0.331
F00 Dementia in Alzheimer's disease	0.668	0.332
O02.1 Missed abortion	0.666	0.334
X59 Exposure to unspecified factor	0.665	0.335
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.665	0.335
D58.0 Hereditary spherocytosis	0.664	0.336
O23 Infections of genito-urinary tract in pregnancy	0.664	0.336
Y46 Antiepileptics and anti-Parkinsonism drugs	0.664	0.336
D69.5 Secondary thrombocytopenia	0.663	0.336
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.663	0.337
W18.5 Trade and service area	0.662	0.338
F45.9 Somatoform disorder, unspecified	0.661	0.338
O22 Venous complications in pregnancy	0.661	0.338
T70 Effects of air pressure and water pressure	0.661	0.339
F41 Other anxiety disorders	0.661	0.339
Y44.2 Anticoagulants	0.660	0.340
T75 Effects of other external causes	0.660	0.340
T87 Complications peculiar to reattachment and amputation	0.659	0.341
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.659	0.341
T81.1 Shock during or resulting from a procedure, not elsewhere classified	0.658	0.342
Q26 Congenital malformations of great veins	0.658	0.342
Q25 Congenital malformations of great arteries	0.658	0.342
Q22 Congenital malformations of pulmonary and tricuspid valves	0.658	0.342
Q20 Congenital malformations of cardiac chambers and connexions	0.658	0.342
O85-O92 Complications predominantly related to the puerperium	0.658	0.342
T50.8 Diagnostic agents	0.657	0.343
T50.7 Analeptics and opioid receptor antagonists	0.657	0.343
T50.6 Antidotes and chelating agents, not elsewhere classified	0.657	0.343
T50.5 Appetite depressants	0.657	0.343
T50.4 Drugs affecting uric acid metabolism	0.657	0.343
T50.3 Electrolytic, caloric and water-balance agents	0.657	0.343
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.657	0.343
T50.1 Loop [high-ceiling] diuretics	0.657	0.343
T50.0 Mineralocorticoids and their antagonists	0.657	0.343
F01 Vascular dementia	0.656	0.344
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.656	0.344
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.656	0.344
J09 Influenza due to certain identified influenza virus	0.656	0.344
D67 Hereditary factor IX deficiency	0.656	0.344
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.656	0.344
F02.0 Dementia in Pick's disease	0.655	0.344
I12 Hypertensive renal disease	0.656	0.344
D57 Sickle-cell disorders	0.655	0.345
D55 Anaemia due to enzyme disorders	0.655	0.345
A09 Diarrhoea and gastro-enteritis of presumed infectious origin	0.655	0.345
J17 Pneumonia in diseases classified elsewhere	0.654	0.346
W06 Fall involving bed	0.654	0.346
D69.4 Other primary thrombocytopenia	0.653	0.346
V80-V89 Other land transport accidents	0.652	0.347
B15-B19 Viral hepatitis	0.652	0.348
S80-S89 Injuries to the knee and lower leg	0.652	0.348
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.651	0.349
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.651	0.349
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.651	0.349
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.650	0.350
T42.1 Iminostilbenes	0.650	0.350
S40-S49 Injuries to the shoulder and upper arm	0.649	0.351
D59.1 Other autoimmune haemolytic anaemias	0.649	0.351
J39 Other diseases of upper respiratory tract	0.649	0.351
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.649	0.351
F25.9 Schizoaffective disorder, unspecified	0.649	0.351
Q28 Other congenital malformations of circulatory system	0.648	0.352
T80 Complications following infusion, transfusion and therapeutic injection	0.648	0.352
Q50-Q56 Congenital malformations of genital organs	0.648	0.352
W25.9 Unspecified place	0.645	0.354
D58.9 Hereditary haemolytic anaemia, unspecified	0.644	0.355
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.643	0.356
T47.1 Other antacids and anti-gastric-secretion drugs	0.643	0.357
I72.4 Aneurysm of artery of lower extremity	0.642	0.358
T74 Maltreatment syndromes	0.642	0.358
T73 Effects of other deprivation	0.642	0.358
T69 Other effects of reduced temperature	0.642	0.358
T67 Effects of heat and light	0.642	0.358
T71 Asphyxiation	0.642	0.358
T66 Unspecified effects of radiation	0.642	0.358
T83.3 Mechanical complication of intra-uterine contraceptive device	0.641	0.358
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.642	0.358
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.641	0.359
X68 Intentional self-poisoning by and exposure to pesticides	0.640	0.360
Y89 Sequelae of other external causes	0.640	0.360
T83.2 Mechanical complication of graft of urinary organ	0.639	0.361
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.639	0.361
X58 Exposure to other specified factors	0.639	0.361
T42.4 Benzodiazepines	0.637	0.363
T21 Burn and corrosion of trunk	0.637	0.363
V04 Pedestrian injured in collision with heavy transport vehicle or bus	0.636	0.363
Y57.5 X-ray contrast media	0.636	0.364
F02.8 Dementia in other specified diseases classified elsewhere	0.636	0.364
Q64 Other congenital malformations of urinary system	0.636	0.364
Y91 Evidence of alcohol involvement determined by level of intoxication	0.635	0.365
Q80-Q89 Other congenital malformations	0.635	0.365
Q00-Q07 Congenital malformations of the nervous system	0.634	0.366
T78.4 Allergy, unspecified	0.634	0.366
F32.3 Severe depressive episode with psychotic symptoms	0.634	0.366
F28 Other nonorganic psychotic disorders	0.633	0.367
F24 Induced delusional disorder	0.633	0.367
F21 Schizotypal disorder	0.633	0.367
Y40.7 Antifungal antibiotics, systemically used	0.633	0.367
Y40.6 Rifamycins	0.633	0.367
Y40.5 Aminoglycosides	0.633	0.367
Y40.4 Tetracyclines	0.633	0.367
Y40.2 Chloramphenicol group	0.633	0.367
D63.1 Anaemia in other chronic diseases classified elsewhere	0.632	0.368
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.632	0.368
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.632	0.368
T42.5 Mixed antiepileptics, not elsewhere classified	0.632	0.368
T42.3 Barbiturates	0.632	0.368
T42.2 Succinimides and oxazolidinediones	0.632	0.368
T42.0 Hydantoin derivatives	0.632	0.368
T43.5 Other and unspecified antipsychotics and neuroleptics	0.632	0.368
Y49 Psychotropic drugs, not elsewhere classified	0.632	0.368
B50 Plasmodium falciparum malaria	0.631	0.369
J91 Pleural effusion in conditions classified elsewhere	0.630	0.370
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.630	0.370
V43.9 Unspecified car occupant injured in traffic accident	0.629	0.371
T81.6 Acute reaction to foreign substance accidentally left during a procedure	0.628	0.371
F05.8 Other delirium	0.628	0.372
F05.1 Delirium superimposed on dementia	0.628	0.372
F22 Persistent delusional disorders	0.628	0.372
X40-X49 Accidental poisoning by and exposure to noxious substances	0.628	0.372
D52 Folate deficiency anaemia	0.628	0.372
F05.0 Delirium not superimposed on dementia, so described	0.626	0.374
I08.1 Disorders of both mitral and tricuspid valves	0.626	0.374
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.625	0.375
F48 Other neurotic disorders	0.625	0.375
F44 Dissociative [conversion] disorders	0.625	0.375
W27.6 Industrial and construction area	0.624	0.376
A68 Relapsing fevers	0.624	0.376
A67 Pinta [carate]	0.624	0.376
A66 Yaws	0.624	0.376
A65 Non-venereal syphilis	0.624	0.376
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters	0.624	0.376
T84.3 Mechanical complication of other bone devices, implants and grafts	0.622	0.377
J15.5 Pneumonia due to Escherichia coli	0.622	0.378
T78.0 Anaphylactic shock due to adverse food reaction	0.621	0.379
D69.0 Allergic purpura	0.620	0.379
A80-A89 Viral infections of the central nervous system	0.620	0.380
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.620	0.380
T88.7 Unspecified adverse effect of drug or medicament	0.620	0.380
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.619	0.381
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.619	0.381
Y57.8 Other drugs and medicaments	0.617	0.382
D80.1 Nonfamilial hypogammaglobulinaemia	0.616	0.384
D69.9 Haemorrhagic condition, unspecified	0.614	0.386
D69.8 Other specified haemorrhagic conditions	0.614	0.386
D69.2 Other nonthrombocytopenic purpura	0.614	0.386
D69.1 Qualitative platelet defects	0.614	0.386
T81.7 Vascular complications following a procedure, not elsewhere classified	0.614	0.386
T20 Burn and corrosion of head and neck	0.610	0.389
F29 Unspecified nonorganic psychosis	0.610	0.390
I65.0 Occlusion and stenosis of vertebral artery	0.609	0.391
F32.9 Depressive episode, unspecified	0.609	0.391
J18.9 Pneumonia, unspecified	0.608	0.392
Q61.9 Cystic kidney disease, unspecified	0.608	0.392
W94 Exposure to high and low air pressure and changes in air pressure	0.608	0.392
S79.9 Unspecified injury of hip and thigh	0.607	0.393
Y53.4 Other laxatives	0.607	0.393
A30-A49 Other bacterial diseases	0.607	0.393
W03 Other fall on same level due to collision with, or pushing by, another person	0.606	0.394
W55 Bitten or struck by other mammals	0.606	0.394
Q23.0 Congenital stenosis of aortic valve	0.606	0.394
V10-V19 Pedal cyclist injured in transport accident	0.605	0.394
I61.8 Other intracerebral haemorrhage	0.605	0.394
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.605	0.395
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.605	0.395
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.603	0.397
T09 Other injuries of spine and trunk, level unspecified	0.602	0.398
J15.9 Bacterial pneumonia, unspecified	0.602	0.398
W01 Fall on same level from slipping, tripping and stumbling	0.602	0.398
F25.0 Schizoaffective disorder, manic type	0.602	0.398
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.601	0.399
S78 Traumatic amputation of hip and thigh	0.600	0.400
S77 Crushing injury of hip and thigh	0.600	0.400
S76 Injury of muscle and tendon at hip and thigh level	0.600	0.400
S75 Injury of blood vessels at hip and thigh level	0.600	0.400
S74 Injury of nerves at hip and thigh level	0.600	0.400
S71 Open wound of hip and thigh	0.600	0.400
W79 Inhalation and ingestion of food causing obstruction of respiratory tract	0.599	0.401
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent	0.598	0.402
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters	0.598	0.402
F45.3 Somatoform autonomic dysfunction	0.598	0.402
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.598	0.402
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.597	0.403
V49 Car occupant injured in other and unspecified transport accidents	0.597	0.403
T36.0 Penicillins	0.597	0.403
I72.9 Aneurysm of unspecified site	0.597	0.403
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.596	0.403

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations