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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77665194
log Bayes Factor = 15.0844
Chromosome 18   position 12,455,794  (GRCh37) Explore rs77665194 on Ensembl!
Variant rs77665194 is part of Cluster X0210

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
O60-O75 Complications of labour and delivery
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
0.999 0.001 0.000
Chapter X Diseases of the respiratory system
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.997 0.003 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.996 0.004 0.000
E70-E90 Metabolic disorders
0.995 0.005 0.000
Chapter XXI Factors influencing health status and contact with health services
0.994 0.006 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.988 0.012 0.000
E10-E14 Diabetes mellitus
0.986 0.014 0.000
M05-M14 Inflammatory polyarthropathies
0.984 0.016 0.000
O70 Perineal laceration during delivery
0.979 0.021 0.000
J09-J18 Influenza and pneumonia
0.979 0.021 0.000
Z51 Other medical care
0.974 0.026 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.973 0.027 0.000
E10 Insulin-dependent diabetes mellitus
0.966 0.034 0.000
Chapter II Neoplasms
0.966 0.034 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.963 0.037 0.000
J18 Pneumonia, organism unspecified
0.961 0.039 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.961 0.039 0.000
Z51.5 Palliative care
0.960 0.040 0.000
O72 Postpartum haemorrhage
0.951 0.049 0.000
M13 Other arthritis
0.947 0.053 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.945 0.055 0.000
E10.9 Without complications
0.945 0.055 0.000
E83 Disorders of mineral metabolism
0.938 0.062 0.000
O70.1 Second degree perineal laceration during delivery
0.934 0.066 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.933 0.067 0.000
J90-J94 Other diseases of pleura
0.931 0.069 0.000
E20-E35 Disorders of other endocrine glands
0.930 0.070 0.000
S60-S69 Injuries to the wrist and hand
0.929 0.071 0.000
J18.9 Pneumonia, unspecified
0.926 0.074 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.923 0.077 0.000
Z43 Attention to artificial openings
0.919 0.081 0.000
Chapter XXII Codes for special purposes
0.917 0.083 0.000
Z51.1 Chemotherapy session for neoplasm
0.915 0.085 0.000
M13.9 Arthritis, unspecified
0.912 0.088 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.912 0.088 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.910 0.090 0.000
M20-M25 Other joint disorders
0.910 0.090 0.000
O70.0 First degree perineal laceration during delivery
0.904 0.096 0.000
O00-O08 Pregnancy with abortive outcome
0.897 0.103 0.000
E11 Non-insulin-dependent diabetes mellitus
0.897 0.103 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.896 0.104 0.000
E87.5 Hyperkalaemia
0.890 0.110 0.000
J00-J06 Acute upper respiratory infections
0.890 0.110 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.889 0.111 0.000
M06 Other rheumatoid arthritis
0.888 0.112 0.000
Y95 Nosocomial condition
0.886 0.114 0.000
Z45 Adjustment and management of implanted device
0.886 0.114 0.000
M80-M85 Disorders of bone density and structure
0.884 0.115 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.879 0.121 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.877 0.123 0.000
O72.1 Other immediate postpartum haemorrhage
0.876 0.124 0.000
M65-M68 Disorders of synovium and tendon
0.875 0.125 0.000
W20-W49 Exposure to inanimate mechanical forces
0.874 0.126 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.872 0.128 0.000
S20-S29 Injuries to the thorax
0.870 0.130 0.000
T81 Complications of procedures, not elsewhere classified
0.868 0.132 0.000
C15-C26 Malignant neoplasms of digestive organs
0.868 0.132 0.000
E87.7 Fluid overload
0.868 0.132 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.868 0.132 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.866 0.134 0.000
Y43 Primarily systemic agents
0.865 0.135 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.857 0.143 0.000
J30-J39 Other diseases of upper respiratory tract
0.853 0.147 0.000
J18.1 Lobar pneumonia, unspecified
0.851 0.149 0.000
S50-S59 Injuries to the elbow and forearm
0.847 0.153 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.845 0.155 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.844 0.156 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.844 0.156 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.842 0.158 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.840 0.160 0.000
Z51.8 Other specified medical care
0.839 0.161 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.834 0.166 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.834 0.166 0.000
S10-S19 Injuries to the neck
0.831 0.169 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.830 0.170 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.829 0.171 0.000
Z47 Other orthopaedic follow-up care
0.827 0.173 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.827 0.173 0.000
M70-M79 Other soft tissue disorders
0.825 0.175 0.000
M06.9 Rheumatoid arthritis, unspecified
0.824 0.176 0.000
C18 Malignant neoplasm of colon
0.821 0.179 0.000
E83.3 Disorders of phosphorus metabolism
0.820 0.180 0.000
M65 Synovitis and tenosynovitis
0.817 0.183 0.000
E11.9 Without complications
0.813 0.187 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.811 0.189 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.811 0.189 0.000
M84 Disorders of continuity of bone
0.810 0.190 0.000
X60-X84 Intentional self-harm
0.810 0.190 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.809 0.191 0.000
D70 Agranulocytosis
0.807 0.193 0.000
E89.0 Postprocedural hypothyroidism
0.806 0.194 0.000
O72.0 Third-stage haemorrhage
0.803 0.197 0.000
Z60 Problems related to social environment
0.803 0.197 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.802 0.197 0.000
J93 Pneumothorax
0.798 0.202 0.000
Chapter VIII Diseases of the ear and mastoid process
0.798 0.202 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.797 0.203 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.796 0.204 0.000
Z37 Outcome of delivery
0.795 0.205 0.000
E83.5 Disorders of calcium metabolism
0.795 0.205 0.000
M31 Other necrotising vasculopathies
0.794 0.206 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.794 0.206 0.000
O04 Medical abortion
0.791 0.209 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.787 0.213 0.000
E10.2 With renal complications
0.787 0.213 0.000
E23 Hypofunction and other disorders of pituitary gland
0.787 0.213 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.787 0.213 0.000
V10-V19 Pedal cyclist injured in transport accident
0.787 0.213 0.000
M05 Seropositive rheumatoid arthritis
0.786 0.214 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.785 0.215 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.783 0.217 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.783 0.217 0.000
Y83.6 Removal of other organ (partial) (total)
0.782 0.218 0.000
E83.4 Disorders of magnesium metabolism
0.782 0.218 0.000
O62 Abnormalities of forces of labour
0.781 0.219 0.000
M35 Other systemic involvement of connective tissue
0.774 0.226 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.773 0.227 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.772 0.228 0.000
Z45.2 Adjustment and management of vascular access device
0.771 0.229 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.770 0.230 0.000
Chapter V Mental and behavioural disorders
0.768 0.232 0.000
J95-J99 Other diseases of the respiratory system
0.767 0.233 0.000
Z43.2 Attention to ileostomy
0.766 0.234 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.766 0.234 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.765 0.235 0.000
Z43.3 Attention to colostomy
0.764 0.236 0.000
J91 Pleural effusion in conditions classified elsewhere
0.764 0.236 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.764 0.236 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.763 0.237 0.000
Y48 Anaesthetics and therapeutic gases
0.763 0.237 0.000
Z44 Fitting and adjustment of external prosthetic device
0.763 0.237 0.000
U80 Agent resistant to penicillin and related antibiotics
0.763 0.237 0.000
W25 Contact with sharp glass
0.762 0.238 0.000
J60-J70 Lung diseases due to external agents
0.760 0.239 0.000
E13 Other specified diabetes mellitus
0.760 0.240 0.000
J92 Pleural plaque
0.760 0.240 0.000
M07 Psoriatic and enteropathic arthropathies
0.759 0.241 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.758 0.242 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.758 0.242 0.000
M60-M63 Disorders of muscles
0.757 0.242 0.000
Z60.2 Living alone
0.758 0.242 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.757 0.243 0.000
M13.94 Arthritis, unspecified (Hand)
0.757 0.243 0.000
E27 Other disorders of adrenal gland
0.756 0.244 0.000
Z29 Need for other prophylactic measures
0.756 0.244 0.000
Z43.1 Attention to gastrostomy
0.754 0.246 0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified
0.754 0.246 0.000
Z37.0 Single live birth
0.754 0.246 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.753 0.247 0.000
S70-S79 Injuries to the hip and thigh
0.750 0.250 0.000
E88 Other metabolic disorders
0.750 0.250 0.000
Z40 Prophylactic surgery
0.749 0.251 0.000
T90 Sequelae of injuries of head
0.749 0.251 0.000
E28 Ovarian dysfunction
0.749 0.251 0.000
Z22 Carrier of infectious disease
0.748 0.252 0.000
M91-M94 Chondropathies
0.747 0.253 0.000
Y43.3 Other antineoplastic drugs
0.747 0.253 0.000
C01 Malignant neoplasm of base of tongue
0.746 0.253 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.745 0.255 0.000
Y83.3 Surgical operation with formation of external stoma
0.745 0.255 0.000
S62 Fracture at wrist and hand level
0.744 0.256 0.000
M22 Disorders of patella
0.744 0.256 0.000
Chapter VI Diseases of the nervous system
0.744 0.256 0.000
R50-R69 General symptoms and signs
0.744 0.256 0.000
M13.0 Polyarthritis, unspecified
0.744 0.256 0.000
S90-S99 Injuries to the ankle and foot
0.743 0.257 0.000
C77.3 Axillary and upper limb lymph nodes
0.743 0.257 0.000
Z51.9 Medical care, unspecified
0.743 0.257 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.743 0.257 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.741 0.259 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.741 0.259 0.000
C18.9 Colon, unspecified
0.740 0.260 0.000
O63 Long labour
0.738 0.262 0.000
J94 Other pleural conditions
0.736 0.264 0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level
0.735 0.265 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.735 0.265 0.000
S80-S89 Injuries to the knee and lower leg
0.734 0.266 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.732 0.268 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.731 0.269 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.730 0.270 0.000
E87.0 Hyperosmolality and hypernatraemia
0.729 0.271 0.000
O72.2 Delayed and secondary postpartum haemorrhage
0.729 0.271 0.000
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device
0.729 0.271 0.000
T79-T79 Certain early complications of trauma
0.728 0.272 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.728 0.272 0.000
C64-C68 Malignant neoplasms of urinary tract
0.726 0.274 0.000
Y52 Agents primarily affecting the cardiovascular system
0.726 0.274 0.000
M00-M03 Infectious arthropathies
0.726 0.274 0.000
Z51.0 Radiotherapy session
0.726 0.274 0.000
V80-V89 Other land transport accidents
0.725 0.275 0.000
C77.0 Lymph nodes of head, face and neck
0.725 0.275 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.725 0.275 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.723 0.277 0.000
R26 Abnormalities of gait and mobility
0.723 0.277 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.723 0.277 0.000
J18.0 Bronchopneumonia, unspecified
0.722 0.278 0.000
D73 Diseases of spleen
0.722 0.278 0.000
E86 Volume depletion
0.722 0.278 0.000
J84 Other interstitial pulmonary diseases
0.722 0.278 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.721 0.279 0.000
D72 Other disorders of white blood cells
0.719 0.281 0.000
O00 Ectopic pregnancy
0.718 0.282 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E40-E46 Malnutrition
0.717 0.283 0.000
O85-O92 Complications predominantly related to the puerperium
0.717 0.283 0.000
O74 Complications of anaesthesia during labour and delivery
0.717 0.283 0.000
O71 Other obstetric trauma
0.717 0.283 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.717 0.283 0.000
O66 Other obstructed labour
0.717 0.283 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.717 0.283 0.000
O61 Failed induction of labour
0.717 0.283 0.000
O60 Preterm delivery
0.717 0.283 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.716 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.716 0.283 0.000
Y10-Y34 Event of undetermined intent
0.716 0.283 0.000
Y00-Y09 Assault
0.716 0.283 0.000
X85-X99 Assault
0.716 0.283 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.716 0.283 0.000
X50-X57 Overexertion, travel and privation
0.716 0.283 0.000
X30-X39 Exposure to forces of nature
0.716 0.283 0.000
X20-X29 Contact with venomous animals and plants
0.716 0.283 0.000
X10-X19 Contact with heat and hot substances
0.716 0.283 0.000
X00-X09 Exposure to smoke, fire and flames
0.716 0.283 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.716 0.283 0.000
W75-W84 Other accidental threats to breathing
0.716 0.283 0.000
W65-W74 Accidental drowning and submersion
0.716 0.283 0.000
W50-W64 Exposure to animate mechanical forces
0.716 0.283 0.000
V98-V99 Other and unspecified transport accidents
0.716 0.283 0.000
V95-V97 Air and space transport accidents
0.716 0.283 0.000
V90-V94 Water transport accidents
0.716 0.283 0.000
V70-V79 Bus occupant injured in transport accident
0.716 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.716 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.716 0.283 0.000
V40-V49 Car occupant injured in transport accident
0.716 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.716 0.283 0.000
V01-V09 Pedestrian injured in transport accident
0.716 0.283 0.000
E87.3 Alkalosis
0.716 0.284 0.000
T33-T35 Frostbite
0.714 0.286 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.714 0.286 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.714 0.286 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.714 0.286 0.000
T00-T07 Injuries involving multiple body regions
0.714 0.286 0.000
E85 Amyloidosis
0.714 0.286 0.000
E84 Cystic fibrosis
0.714 0.286 0.000
E79 Disorders of purine and pyrimidine metabolism
0.714 0.286 0.000
E77 Disorders of glycoprotein metabolism
0.714 0.286 0.000
E76 Disorders of glycosaminoglycan metabolism
0.714 0.286 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.714 0.286 0.000
E74 Other disorders of carbohydrate metabolism
0.714 0.286 0.000
E73 Lactose intolerance
0.714 0.286 0.000
E72 Other disorders of amino-acid metabolism
0.714 0.286 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.714 0.286 0.000
E70 Disorders of aromatic amino-acid metabolism
0.714 0.286 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.714 0.286 0.000
Z54 Convalescence
0.713 0.287 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.712 0.287 0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress
0.712 0.288 0.000
O73 Retained placenta and membranes, without haemorrhage
0.712 0.288 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.709 0.290 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.709 0.291 0.000
S20 Superficial injury of thorax
0.709 0.291 0.000
Z52 Donors of organs and tissues
0.708 0.292 0.000
J00 Acute nasopharyngitis [common cold]
0.708 0.292 0.000
Y42.7 Androgens and anabolic congeners
0.707 0.293 0.000
E12 Malnutrition-related diabetes mellitus
0.707 0.293 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.706 0.293 0.000
Z41 Procedures for purposes other than remedying health state
0.706 0.294 0.000
M14 Arthropathies in other diseases classified elsewhere
0.705 0.294 0.000
M12 Other specific arthropathies
0.705 0.294 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.705 0.294 0.000
M08 Juvenile arthritis
0.705 0.294 0.000
Y84.0 Cardiac catheterisation
0.705 0.295 0.000
C04 Malignant neoplasm of floor of mouth
0.705 0.295 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.704 0.296 0.000
Y46.4 Iminostilbenes
0.703 0.297 0.000
Y43.0 Antiallergic and antiemetic drugs
0.703 0.297 0.000
C18.4 Transverse colon
0.702 0.297 0.000
O70.9 Perineal laceration during delivery, unspecified
0.702 0.298 0.000
O70.3 Fourth degree perineal laceration during delivery
0.702 0.298 0.000
J17 Pneumonia in diseases classified elsewhere
0.702 0.298 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.702 0.298 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.702 0.298 0.000
J12 Viral pneumonia, not elsewhere classified
0.702 0.298 0.000
J11 Influenza, virus not identified
0.702 0.298 0.000
J10 Influenza due to identified influenza virus
0.702 0.298 0.000
J14 Pneumonia due to Haemophilus influenzae
0.702 0.298 0.000
J09 Influenza due to certain identified influenza virus
0.702 0.298 0.000
M21 Other acquired deformities of limbs
0.701 0.299 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.701 0.299 0.000
J35 Chronic diseases of tonsils and adenoids
0.701 0.299 0.000
J93.9 Pneumothorax, unspecified
0.700 0.300 0.000
W00-W19 Falls
0.700 0.300 0.000
J02 Acute pharyngitis
0.700 0.300 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.699 0.301 0.000
Z43.6 Attention to other artificial openings of urinary tract
0.699 0.301 0.000
M35.3 Polymyalgia rheumatica
0.699 0.301 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.699 0.301 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.699 0.301 0.000
M34 Systemic sclerosis
0.698 0.301 0.000
Z51.6 Desensitisation to allergens
0.698 0.302 0.000
S52 Fracture of forearm
0.698 0.302 0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress
0.698 0.302 0.000
M11 Other crystal arthropathies
0.697 0.303 0.000
C21 Malignant neoplasm of anus and anal canal
0.697 0.303 0.000
E65-E68 Obesity and other hyperalimentation
0.695 0.305 0.000
O03 Spontaneous abortion
0.695 0.305 0.000
C10 Malignant neoplasm of oropharynx
0.694 0.305 0.000
S68 Traumatic amputation of wrist and hand
0.694 0.305 0.000
E89.2 Postprocedural hypoparathyroidism
0.694 0.306 0.000
E10.8 With unspecified complications
0.692 0.307 0.000
E10.7 With multiple complications
0.692 0.307 0.000
E10.6 With other specified complications
0.692 0.307 0.000
E10.5 With peripheral circulatory complications
0.692 0.307 0.000
E10.4 With neurological complications
0.692 0.307 0.000
E10.1 With ketoacidosis
0.692 0.307 0.000
E10.0 With coma
0.692 0.307 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.692 0.308 0.000
Y40 Systemic antibiotics
0.692 0.308 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.692 0.308 0.000
R56 Convulsions, not elsewhere classified
0.691 0.309 0.000
Y59 Other and unspecified vaccines and biological substances
0.690 0.310 0.000
Y58 Bacterial vaccines
0.690 0.310 0.000
Y57 Other and unspecified drugs and medicaments
0.690 0.310 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.690 0.310 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.690 0.310 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.690 0.310 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.690 0.310 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.690 0.310 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.690 0.310 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.690 0.310 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.690 0.310 0.000
J18.8 Other pneumonia, organism unspecified
0.689 0.311 0.000
J18.2 Hypostatic pneumonia, unspecified
0.689 0.311 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.689 0.311 0.000
E87.4 Mixed disorder of acid-base balance
0.689 0.311 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.689 0.311 0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.688 0.312 0.000
T91 Sequelae of injuries of neck and trunk
0.686 0.314 0.000
J38.7 Other diseases of larynx
0.686 0.314 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.685 0.315 0.000
E11.3 With ophthalmic complications
0.684 0.316 0.000
Chapter XI Diseases of the digestive system
0.684 0.316 0.000
V20-V29 Motorcycle rider injured in transport accident
0.683 0.317 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.682 0.318 0.000
W25.9 Unspecified place
0.682 0.318 0.000
J38.1 Polyp of vocal cord and larynx
0.682 0.318 0.000
O72.3 Postpartum coagulation defects
0.682 0.318 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.681 0.319 0.000
Chapter I Certain infectious and parasitic diseases
0.681 0.319 0.000
R25 Abnormal involuntary movements
0.681 0.319 0.000
Z49 Care involving dialysis
0.681 0.319 0.000
E11.1 With ketoacidosis
0.680 0.320 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.680 0.320 0.000
S63.6 Sprain and strain of finger(s)
0.679 0.321 0.000
M13.8 Other specified arthritis
0.679 0.321 0.000
M13.1 Monoarthritis, not elsewhere classified
0.679 0.321 0.000
E87.6 Hypokalaemia
0.679 0.321 0.000
O80-O84 Delivery
0.678 0.322 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.677 0.323 0.000
S29 Other and unspecified injuries of thorax
0.677 0.323 0.000
D00-D09 In situ neoplasms
0.677 0.323 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.677 0.323 0.000
S51 Open wound of forearm
0.676 0.324 0.000
J92.0 Pleural plaque with presence of asbestos
0.675 0.325 0.000
Z31 Procreative management
0.675 0.325 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.675 0.325 0.000
J06.9 Acute upper respiratory infection, unspecified
0.675 0.325 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.674 0.326 0.000
E10.3 With ophthalmic complications
0.674 0.326 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.674 0.326 0.000
C92 Myeloid leukaemia
0.673 0.327 0.000
T98 Sequelae of other and unspecified effects of external causes
0.673 0.327 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.673 0.327 0.000
E83.8 Other disorders of mineral metabolism
0.673 0.327 0.000
E83.2 Disorders of zinc metabolism
0.673 0.327 0.000
E83.0 Disorders of copper metabolism
0.673 0.327 0.000
M31.3 Wegener's granulomatosis
0.672 0.328 0.000
O20 Haemorrhage in early pregnancy
0.671 0.329 0.000
R23 Other skin changes
0.671 0.329 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.671 0.329 0.000
M65.3 Trigger finger
0.670 0.330 0.000
Z50 Care involving use of rehabilitation procedures
0.670 0.330 0.000
J04 Acute laryngitis and tracheitis
0.669 0.331 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.669 0.331 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.669 0.331 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.669 0.331 0.000
Y98 Lifestyle-related condition
0.669 0.331 0.000
Y97 Environmental-pollution-related condition
0.669 0.331 0.000
Y96 Work-related condition
0.669 0.331 0.000
C79 Secondary malignant neoplasm of other sites
0.668 0.332 0.000
M25 Other joint disorders, not elsewhere classified
0.668 0.332 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.667 0.333 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.667 0.333 0.000
E34 Other endocrine disorders
0.667 0.333 0.000
E32 Diseases of thymus
0.667 0.333 0.000
E31 Polyglandular dysfunction
0.667 0.333 0.000
E30 Disorders of puberty, not elsewhere classified
0.667 0.333 0.000
E29 Testicular dysfunction
0.667 0.333 0.000
E26 Hyperaldosteronism
0.667 0.333 0.000
E25 Adrenogenital disorders
0.667 0.333 0.000
E24 Cushing's syndrome
0.667 0.333 0.000
E20 Hypoparathyroidism
0.667 0.333 0.000
C18.3 Hepatic flexure
0.666 0.333 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.666 0.334 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.666 0.334 0.000
S40-S49 Injuries to the shoulder and upper arm
0.666 0.334 0.000
M86-M90 Other osteopathies
0.666 0.334 0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head
0.666 0.334 0.000
O04.4 Incomplete, without complication
0.666 0.334 0.000
S65 Injury of blood vessels at wrist and hand level
0.666 0.334 0.000
S60 Superficial injury of wrist and hand
0.666 0.334 0.000
J36 Peritonsillar abscess
0.666 0.334 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.665 0.335 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.665 0.335 0.000
D60-D64 Aplastic and other anaemias
0.664 0.336 0.000
S67 Crushing injury of wrist and hand
0.664 0.336 0.000
Z37.1 Single stillbirth
0.663 0.337 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.663 0.337 0.000
Z45.1 Adjustment and management of infusion pump
0.662 0.338 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.661 0.339 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.660 0.340 0.000
U80.0 Penicillin resistant agent
0.660 0.340 0.000
Z43.9 Attention to unspecified artificial opening
0.659 0.341 0.000
Z43.8 Attention to other artificial openings
0.659 0.341 0.000
Z43.7 Attention to artificial vagina
0.659 0.341 0.000
Z43.5 Attention to cyctostomy
0.659 0.341 0.000
Z43.4 Attention to other artificial openings of digestive tract
0.659 0.341 0.000
Z43.0 Attention to tracheostomy
0.659 0.341 0.000
Y83.0 Surgical operation with transplant of whole organ
0.658 0.342 0.000
W29 Contact with other powered hand tools and household machinery
0.658 0.342 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.658 0.342 0.000
W22 Striking against or struck by other objects
0.657 0.343 0.000
C25 Malignant neoplasm of pancreas
0.656 0.344 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.655 0.345 0.000
O04.9 Complete or unspecified, without complication
0.655 0.345 0.000
S12 Fracture of neck
0.655 0.345 0.000
M84.0 Malunion of fracture
0.654 0.346 0.000
Y83.8 Other surgical procedures
0.654 0.346 0.000
M13.98 Arthritis, unspecified (Other)
0.654 0.346 0.000
M13.93 Arthritis, unspecified (Forearm)
0.654 0.346 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.654 0.346 0.000
R56.8 Other and unspecified convulsions
0.654 0.346 0.000
T87 Complications peculiar to reattachment and amputation
0.654 0.346 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.653 0.346 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.652 0.347 0.000
O64.1 Obstructed labour due to breech presentation
0.652 0.348 0.000
D55-D59 Haemolytic anaemias
0.652 0.348 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.652 0.348 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.652 0.348 0.000
M33 Dermatopolymyositis
0.652 0.348 0.000
M32 Systemic lupus erythematosus
0.652 0.348 0.000
M30 Polyarteritis nodosa and related conditions
0.652 0.348 0.000
T92 Sequelae of injuries of upper limb
0.652 0.348 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.652 0.348 0.000
O70.2 Third degree perineal laceration during delivery
0.652 0.348 0.000
E11.2 With renal complications
0.651 0.349 0.000
S69 Other and unspecified injuries of wrist and hand
0.651 0.349 0.000
M77 Other enthesopathies
0.651 0.349 0.000
E22 Hyperfunction of pituitary gland
0.650 0.350 0.000
C45 Mesothelioma
0.650 0.350 0.000
J37 Chronic laryngitis and laryngotracheitis
0.650 0.350 0.000
M23 Internal derangement of knee
0.650 0.350 0.000
E83.1 Disorders of iron metabolism
0.649 0.350 0.000
Y43.4 Immunosuppressive agents
0.649 0.351 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.647 0.353 0.000
T66-T78 Other and unspecified effects of external causes
0.647 0.353 0.000
Y83.5 Amputation of limb(s)
0.646 0.354 0.000
M45-M49 Spondylopathies
0.645 0.354 0.000
R20 Disturbances of skin sensation
0.645 0.355 0.000
M75 Shoulder lesions
0.645 0.355 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.645 0.355 0.000
Z46 Fitting and adjustment of other devices
0.645 0.355 0.000
E21.3 Hyperparathyroidism, unspecified
0.645 0.355 0.000
T86 Failure and rejection of transplanted organs and tissues
0.644 0.356 0.000
O08 Complications following abortion and ectopic and molar pregnancy
0.643 0.357 0.000
O07 Failed attempted abortion
0.643 0.357 0.000
O06 Unspecified abortion
0.643 0.357 0.000
O05 Other abortion
0.643 0.357 0.000
O01 Hydatidiform mole
0.643 0.357 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.643 0.357 0.000
E11.8 With unspecified complications
0.643 0.357 0.000
E11.7 With multiple complications
0.643 0.357 0.000
E11.6 With other specified complications
0.643 0.357 0.000
E11.0 With coma
0.643 0.357 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.643 0.357 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.642 0.358 0.000
E89.8 Other postprocedural endocrine and metabolic disorders
0.642 0.358 0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.642 0.358 0.000
E89.5 Postprocedural testicular hypofunction
0.642 0.358 0.000
E89.4 Postprocedural ovarian failure
0.642 0.358 0.000
E89.3 Postprocedural hypopituitarism
0.642 0.358 0.000
E89.1 Postprocedural hypoinsulinaemia
0.642 0.358 0.000
Z22.3 Carrier of other specified bacterial diseases
0.642 0.358 0.000
M31.6 Other giant cell arteritis
0.641 0.359 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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