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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3117582
log Bayes Factor = 377.466
Chromosome 6   position 31,620,520  (GRCh37) Explore rs3117582 on Ensembl!
Variant rs3117582 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
D64.9 Anaemia, unspecified
1.000 0.000 0.000
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
E10.3 With ophthalmic complications
1.000 0.000 0.000
E16.2 Hypoglycaemia, unspecified
1.000 0.000 0.000
H36.0 Diabetic retinopathy
1.000 0.000 0.000
J45.9 Asthma, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
M35.0 Sicca syndrome [Sjogren]
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E14 Unspecified diabetes mellitus
1.000 0.000 0.000
E11 Non-insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
J44 Other chronic obstructive pulmonary disease
1.000 0.000 0.000
R31 Unspecified haematuria
0.000 0.000 1.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
1.000 0.000 0.000
H30-H36 Disorders of choroid and retina
1.000 0.000 0.000
J40-J47 Chronic lower respiratory diseases
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
E10.1 With ketoacidosis
1.000 0.000 0.000
K90 Intestinal malabsorption
1.000 0.000 0.000
M35 Other systemic involvement of connective tissue
1.000 0.000 0.000
G50-G59 Nerve, nerve root and plexus disorders
1.000 0.000 0.000
K70-K77 Diseases of liver
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
D60-D64 Aplastic and other anaemias
1.000 0.000 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
1.000 0.000 0.000
E89.0 Postprocedural hypothyroidism
1.000 0.000 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
1.000 0.000 0.000
K75 Other inflammatory liver diseases
1.000 0.000 0.000
N00-N08 Glomerular diseases
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
D64 Other anaemias
1.000 0.000 0.000
E16 Other disorders of pancreatic internal secretion
1.000 0.000 0.000
H36 Retinal disorders in diseases classified elsewhere
1.000 0.000 0.000
D50-D53 Nutritional anaemias
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
E27.1 Primary adrenocortical insufficiency
1.000 0.000 0.000
J45 Asthma
1.000 0.000 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
1.000 0.000 0.000
E14.3 With ophthalmic complications
1.000 0.000 0.000
D69 Purpura and other haemorrhagic conditions
1.000 0.000 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
0.983 0.000 0.017
Chapter II Neoplasms
1.000 0.000 0.000
E20-E35 Disorders of other endocrine glands
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
I73 Other peripheral vascular diseases
1.000 0.000 0.000
M20.1 Hallux valgus (acquired)
0.000 0.000 1.000
D50 Iron deficiency anaemia
1.000 0.000 0.000
G56 Mononeuropathies of upper limb
1.000 0.000 0.000
G56.0 Carpal tunnel syndrome
1.000 0.000 0.000
K75.4 Autoimmune hepatitis
1.000 0.000 0.000
E27 Other disorders of adrenal gland
1.000 0.000 0.000
D69.6 Thrombocytopenia, unspecified
0.999 0.001 0.000
B35-B49 Mycoses
0.999 0.001 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.999 0.001 0.000
Chapter XX External causes of morbidity and mortality
0.999 0.001 0.000
N04 Nephrotic syndrome
0.999 0.001 0.000
M15-M19 Arthrosis
0.999 0.001 0.000
K90-K93 Other diseases of the digestive system
0.999 0.001 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.999 0.001 0.000
E11.3 With ophthalmic complications
0.999 0.001 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.999 0.001 0.000
D50.9 Iron deficiency anaemia, unspecified
0.999 0.001 0.000
B37 Candidiasis
0.999 0.001 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.999 0.001 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.999 0.001 0.000
E70-E90 Metabolic disorders
0.999 0.001 0.000
Chapter VI Diseases of the nervous system
0.999 0.001 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.998 0.002 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.998 0.002 0.000
D70 Agranulocytosis
0.998 0.002 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.998 0.002 0.000
N04.9 Unspecified
0.998 0.002 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.998 0.002 0.000
E11.9 Without complications
0.997 0.003 0.000
M18 Arthrosis of first carpometacarpal joint
0.997 0.003 0.000
C83.3 Large cell (diffuse)
0.996 0.004 0.000
C15-C26 Malignant neoplasms of digestive organs
0.995 0.005 0.000
I73.0 Raynaud's syndrome
0.995 0.005 0.000
I74 Arterial embolism and thrombosis
0.995 0.005 0.000
B37.8 Candidiasis of other sites
0.995 0.005 0.000
E10.2 With renal complications
0.994 0.006 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.994 0.006 0.000
K90.9 Intestinal malabsorption, unspecified
0.994 0.006 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.993 0.007 0.000
N18 Chronic renal failure
0.993 0.007 0.000
N05 Unspecified nephritic syndrome
0.992 0.008 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.992 0.008 0.000
N17-N19 Renal failure
0.990 0.008 0.001
I73.9 Peripheral vascular disease, unspecified
0.991 0.009 0.000
E14.9 Without complications
0.991 0.009 0.000
D80-D89 Certain disorders involving the immune mechanism
0.991 0.009 0.000
M24 Other specific joint derangements
0.991 0.009 0.000
E10.4 With neurological complications
0.990 0.010 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.990 0.010 0.000
H34 Retinal vascular occlusions
0.989 0.011 0.000
I77 Other disorders of arteries and arterioles
0.988 0.012 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.987 0.013 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.986 0.014 0.000
C85.1 B-cell lymphoma, unspecified
0.986 0.014 0.000
E50-E64 Other nutritional deficiencies
0.986 0.014 0.000
H06.2 Dysthyroid exophthalmos
0.985 0.015 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.984 0.016 0.000
C91 Lymphoid leukaemia
0.982 0.018 0.000
C20 Malignant neoplasm of rectum
0.981 0.019 0.000
N18.9 Chronic renal failure, unspecified
0.981 0.019 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.980 0.020 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.978 0.022 0.000
K75.8 Other specified inflammatory liver diseases
0.978 0.022 0.000
L10-L14 Bullous disorders
0.975 0.025 0.000
K73 Chronic hepatitis, not elsewhere classified
0.975 0.025 0.000
K50-K52 Noninfective enteritis and colitis
0.447 0.025 0.527
R30-R39 Symptoms and signs involving the urinary system
0.000 0.027 0.973
B37.9 Candidiasis, unspecified
0.972 0.028 0.000
H34.8 Other retinal vascular occlusions
0.971 0.029 0.000
M17 Gonarthrosis [arthrosis of knee]
0.971 0.029 0.000
R30 Pain associated with micturition
0.000 0.030 0.970
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.970 0.030 0.000
R30.0 Dysuria
0.000 0.030 0.970
I60-I69 Cerebrovascular diseases
0.968 0.032 0.000
N05.2 Diffuse membranous glomerulonephritis
0.968 0.032 0.000
E06 Thyroiditis
0.966 0.034 0.000
H25-H28 Disorders of lens
0.965 0.035 0.000
M20 Acquired deformities of fingers and toes
0.001 0.036 0.963
E53 Deficiency of other B group vitamins
0.964 0.036 0.000
I77.1 Stricture of artery
0.963 0.037 0.000
I63 Cerebral infarction
0.963 0.037 0.000
N18.3 Chronic kidney disease, stage 3
0.962 0.038 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.961 0.039 0.000
C81 Hodgkin's disease
0.960 0.040 0.000
D61 Other aplastic anaemias
0.960 0.040 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.959 0.041 0.000
L13 Other bullous disorders
0.959 0.041 0.000
D51 Vitamin B12 deficiency anaemia
0.957 0.043 0.000
W00-W19 Falls
0.957 0.043 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.955 0.045 0.000
L50-L54 Urticaria and erythema
0.955 0.045 0.000
D86 Sarcoidosis
0.955 0.045 0.000
A30-A49 Other bacterial diseases
0.953 0.047 0.000
M17.1 Other primary gonarthrosis
0.953 0.047 0.000
H43-H45 Disorders of vitreous body and globe
0.953 0.047 0.000
C91.1 Chronic lymphocytic leukaemia
0.952 0.048 0.000
W19 Unspecified fall
0.952 0.048 0.000
E11.5 With peripheral circulatory complications
0.951 0.049 0.000
M20.5 Other deformities of toe(s) (acquired)
0.000 0.050 0.950
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.949 0.051 0.000
L13.0 Dermatitis herpetiformis
0.948 0.052 0.000
E53.8 Deficiency of other specified B group vitamins
0.948 0.052 0.000
H26 Other cataract
0.946 0.054 0.000
H26.9 Cataract, unspecified
0.943 0.057 0.000
G51 Facial nerve disorders
0.942 0.058 0.000
C16 Malignant neoplasm of stomach
0.941 0.059 0.000
A41 Other septicaemia
0.941 0.059 0.000
J46 Status asthmaticus
0.941 0.059 0.000
J90-J94 Other diseases of pleura
0.940 0.060 0.000
E06.3 Autoimmune thyroiditis
0.940 0.060 0.000
M34 Systemic sclerosis
0.940 0.060 0.000
W19.9 Unspecified place
0.938 0.062 0.000
A41.9 Septicaemia, unspecified
0.937 0.063 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.936 0.064 0.000
K73.2 Chronic active hepatitis, not elsewhere classified
0.935 0.065 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.935 0.065 0.000
Y42.7 Androgens and anabolic congeners
0.934 0.066 0.000
M24.1 Other articular cartilage disorders
0.933 0.067 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.932 0.068 0.000
H43 Disorders of vitreous body
0.932 0.068 0.000
E11.1 With ketoacidosis
0.929 0.071 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.928 0.072 0.000
H05 Disorders of orbit
0.927 0.073 0.000
B25-B34 Other viral diseases
0.926 0.074 0.000
L20-L30 Dermatitis and eczema
0.926 0.074 0.000
M80-M85 Disorders of bone density and structure
0.925 0.075 0.000
D61.9 Aplastic anaemia, unspecified
0.925 0.075 0.000
D50.8 Other iron deficiency anaemias
0.922 0.078 0.000
N18.0 End-stage renal disease
0.920 0.080 0.000
D86.9 Sarcoidosis, unspecified
0.919 0.081 0.000
H35 Other retinal disorders
0.919 0.081 0.000
M86-M90 Other osteopathies
0.919 0.081 0.000
J90 Pleural effusion, not elsewhere classified
0.919 0.081 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.919 0.081 0.000
V20-V29 Motorcycle rider injured in transport accident
0.918 0.082 0.000
H43.1 Vitreous haemorrhage
0.918 0.082 0.000
L94 Other localised connective tissue disorders
0.917 0.083 0.000
R35 Polyuria
0.000 0.084 0.916
L52 Erythema nodosum
0.915 0.085 0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.000 0.085 0.915
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.914 0.086 0.000
M60-M63 Disorders of muscles
0.913 0.087 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.912 0.088 0.000
Y43 Primarily systemic agents
0.911 0.089 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.910 0.090 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.910 0.090 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.905 0.095 0.000
I77.6 Arteritis, unspecified
0.904 0.096 0.000
D80 Immunodeficiency with predominantly antibody defects
0.903 0.097 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.902 0.098 0.000
N18.4 Chronic kidney disease, stage 4
0.900 0.100 0.000
D55-D59 Haemolytic anaemias
0.898 0.102 0.000
K74 Fibrosis and cirrhosis of liver
0.896 0.104 0.000
M15 Polyarthrosis
0.896 0.104 0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.895 0.105 0.000
N17 Acute renal failure
0.894 0.106 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.894 0.106 0.000
C04 Malignant neoplasm of floor of mouth
0.894 0.106 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.893 0.107 0.000
H35.8 Other specified retinal disorders
0.892 0.108 0.000
L28 Lichen simplex chronicus and prurigo
0.890 0.110 0.000
D69.4 Other primary thrombocytopenia
0.890 0.110 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.889 0.111 0.000
B25 Cytomegaloviral disease
0.885 0.115 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.885 0.115 0.000
G59.0 Diabetic mononeuropathy
0.884 0.116 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.883 0.117 0.000
L92.0 Granuloma annulare
0.881 0.119 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.880 0.120 0.000
M32 Systemic lupus erythematosus
0.880 0.120 0.000
I63.8 Other cerebral infarction
0.880 0.120 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.878 0.122 0.000
V40-V49 Car occupant injured in transport accident
0.877 0.123 0.000
C92 Myeloid leukaemia
0.877 0.123 0.000
B07 Viral warts
0.876 0.124 0.000
M35.3 Polymyalgia rheumatica
0.876 0.124 0.000
M86 Osteomyelitis
0.876 0.124 0.000
H30 Chorioretinal inflammation
0.872 0.128 0.000
G51.0 Bell's palsy
0.872 0.128 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.872 0.128 0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue
0.871 0.129 0.000
Y42.2 Antithyroid drugs
0.869 0.131 0.000
C81.9 Hodgkin's disease, unspecified
0.868 0.132 0.000
Y43.3 Other antineoplastic drugs
0.868 0.132 0.000
C81.1 Nodular sclerosis
0.866 0.134 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.866 0.134 0.000
A63.0 Anogenital (venereal) warts
0.866 0.134 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.865 0.135 0.000
E10.0 With coma
0.864 0.136 0.000
J84 Other interstitial pulmonary diseases
0.864 0.136 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.863 0.137 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.861 0.138 0.000
B37.0 Candidal stomatitis
0.861 0.139 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.861 0.139 0.000
L93 Lupus erythematosus
0.861 0.139 0.000
E88 Other metabolic disorders
0.860 0.140 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.860 0.140 0.000
J84.9 Interstitial pulmonary disease, unspecified
0.860 0.140 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.859 0.141 0.000
I65.2 Occlusion and stenosis of carotid artery
0.859 0.141 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.858 0.142 0.000
E14.8 With unspecified complications
0.858 0.142 0.000
C88 Malignant immunoproliferative diseases
0.857 0.143 0.000
B25.9 Cytomegaloviral disease, unspecified
0.856 0.144 0.000
N08.5 Glomerular disorders in systemic connective tissue disorders
0.856 0.144 0.000
G51.9 Disorder of facial nerve, unspecified
0.856 0.144 0.000
L28.0 Lichen simplex chronicus
0.854 0.146 0.000
W20-W49 Exposure to inanimate mechanical forces
0.853 0.147 0.000
I10-I15 Hypertensive diseases
0.853 0.147 0.000
K73.9 Chronic hepatitis, unspecified
0.852 0.148 0.000
C07 Malignant neoplasm of parotid gland
0.852 0.148 0.000
D69.2 Other nonthrombocytopenic purpura
0.852 0.148 0.000
M17.0 Primary gonarthrosis, bilateral
0.851 0.149 0.000
D73 Diseases of spleen
0.851 0.149 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.849 0.151 0.000
C16.9 Stomach, unspecified
0.848 0.152 0.000
C83.0 Small cell (diffuse)
0.847 0.152 0.000
K72 Hepatic failure, not elsewhere classified
0.847 0.153 0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)
0.847 0.153 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.846 0.154 0.000
C23 Malignant neoplasm of gallbladder
0.845 0.155 0.000
M21 Other acquired deformities of limbs
0.845 0.155 0.000
N05.1 Focal and segmental glomerular lesions
0.844 0.156 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.842 0.158 0.000
E10.5 With peripheral circulatory complications
0.842 0.158 0.000
E14.1 With ketoacidosis
0.841 0.159 0.000
H05.2 Exophthalmic conditions
0.840 0.160 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.839 0.161 0.000
Q43 Other congenital malformations of intestine
0.839 0.161 0.000
K74.6 Other and unspecified cirrhosis of liver
0.839 0.161 0.000
N04.2 Diffuse membranous glomerulonephritis
0.838 0.162 0.000
I74.8 Embolism and thrombosis of other arteries
0.835 0.165 0.000
J33 Nasal polyp
0.834 0.166 0.000
N05.9 Unspecified
0.834 0.166 0.000
M24.11 Other articular cartilage disorders (Shoulder region)
0.833 0.167 0.000
E55 Vitamin D deficiency
0.832 0.168 0.000
J33.0 Polyp of nasal cavity
0.830 0.170 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.830 0.170 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.830 0.170 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.829 0.171 0.000
W19.2 School, other institution and public administrative area
0.829 0.171 0.000
G30-G32 Other degenerative diseases of the nervous system
0.829 0.171 0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van
0.828 0.172 0.000
E10.8 With unspecified complications
0.827 0.173 0.000
J30-J39 Other diseases of upper respiratory tract
0.826 0.174 0.000
I05-I09 Chronic rheumatic heart diseases
0.825 0.175 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.823 0.177 0.000
E07 Other disorders of thyroid
0.821 0.179 0.000
H34.2 Other retinal artery occlusions
0.820 0.180 0.000
G55.3 Nerve root and plexus compressions in other dorsopathies
0.819 0.181 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.819 0.181 0.000
C83.7 Burkitt's tumour
0.819 0.181 0.000
I12 Hypertensive renal disease
0.818 0.182 0.000
M86.9 Osteomyelitis, unspecified
0.817 0.183 0.000
M81 Osteoporosis without pathological fracture
0.817 0.183 0.000
M80 Osteoporosis with pathological fracture
0.816 0.183 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.816 0.184 0.000
C02.9 Tongue, unspecified
0.815 0.185 0.000
E10.7 With multiple complications
0.814 0.186 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.814 0.186 0.000
G56.1 Other lesions of median nerve
0.814 0.186 0.000
W50-W64 Exposure to animate mechanical forces
0.813 0.187 0.000
N04.1 Focal and segmental glomerular lesions
0.812 0.187 0.000
J33.9 Nasal polyp, unspecified
0.813 0.187 0.000
G52 Disorders of other cranial nerves
0.812 0.188 0.000
C91.9 Lymphoid leukaemia, unspecified
0.811 0.189 0.000
J43 Emphysema
0.809 0.190 0.000
H02 Other disorders of eyelid
0.809 0.191 0.000
C91.0 Acute lymphoblastic leukaemia
0.809 0.191 0.000
Chapter VIII Diseases of the ear and mastoid process
0.809 0.191 0.000
B44 Aspergillosis
0.808 0.192 0.000
H26.1 Traumatic cataract
0.807 0.193 0.000
D86.3 Sarcoidosis of skin
0.807 0.193 0.000
B02 Zoster [herpes zoster]
0.807 0.193 0.000
D50.1 Sideropenic dysphagia
0.806 0.194 0.000
E14.2 Withrenal complications
0.805 0.194 0.000
R04.0 Epistaxis
0.000 0.195 0.805
G70-G73 Diseases of myoneural junction and muscle
0.805 0.195 0.000
M35.1 Other overlap syndromes
0.804 0.196 0.000
B00 Herpesviral [herpes simplex] infections
0.804 0.196 0.000
E31 Polyglandular dysfunction
0.802 0.198 0.000
C25 Malignant neoplasm of pancreas
0.800 0.200 0.000
C83.1 Small cleaved cell (diffuse)
0.799 0.201 0.000
E10.6 With other specified complications
0.799 0.201 0.000
D59 Acquired haemolytic anaemia
0.799 0.201 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.799 0.201 0.000
N17.9 Acute renal failure, unspecified
0.798 0.202 0.000
M60 Myositis
0.798 0.202 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.798 0.202 0.000
M34.0 Progressive systemic sclerosis
0.798 0.202 0.000
E51 Thiamine deficiency
0.796 0.204 0.000
B37.7 Candidal septicaemia
0.796 0.204 0.000
W19.3 Sports and athletics area
0.795 0.205 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.795 0.205 0.000
J60-J70 Lung diseases due to external agents
0.793 0.207 0.000
M20.3 Other deformity of hallux (acquired)
0.000 0.207 0.793
D00-D09 In situ neoplasms
0.793 0.207 0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.792 0.208 0.000
I12.9 Hypertensive renal disease without renal failure
0.792 0.208 0.000
Y52 Agents primarily affecting the cardiovascular system
0.791 0.209 0.000
K75.3 Granulomatous hepatitis, not elsewhere classified
0.790 0.210 0.000
E73 Lactose intolerance
0.789 0.211 0.000
G55.0 Nerve root and plexus compressions in neoplastic disease
0.788 0.212 0.000
M24.5 Contracture of joint
0.788 0.212 0.000
M34.1 CR(E)ST syndrome
0.788 0.212 0.000
C15 Malignant neoplasm of oesophagus
0.787 0.213 0.000
H00.1 Chalazion
0.000 0.213 0.787
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.787 0.213 0.000
M35.7 Hypermobility syndrome
0.786 0.214 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.785 0.215 0.000
H31 Other disorders of choroid
0.783 0.217 0.000
K35-K38 Diseases of appendix
0.783 0.217 0.000
L50 Urticaria
0.783 0.217 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.783 0.217 0.000
H27 Other disorders of lens
0.782 0.218 0.000
D83 Common variable immunodeficiency
0.782 0.218 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.781 0.219 0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.781 0.219 0.000
G56.4 Causalgia
0.781 0.219 0.000
H30.9 Chorioretinal inflammation, unspecified
0.781 0.219 0.000
C04.0 Anterior floor of mouth
0.781 0.219 0.000
J92 Pleural plaque
0.780 0.220 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.779 0.221 0.000
L08 Other local infections of skin and subcutaneous tissue
0.779 0.221 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.779 0.221 0.000
H35.2 Other proliferative retinopathy
0.778 0.222 0.000
M33 Dermatopolymyositis
0.777 0.223 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.000 0.223 0.777
X10-X19 Contact with heat and hot substances
0.777 0.223 0.000
I71 Aortic aneurysm and dissection
0.776 0.224 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.776 0.224 0.000
C34 Malignant neoplasm of bronchus and lung
0.773 0.227 0.000
M21.0 Valgus deformity, not elsewhere classified
0.773 0.227 0.000
C05 Malignant neoplasm of palate
0.773 0.227 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.773 0.227 0.000
D69.5 Secondary thrombocytopenia
0.773 0.227 0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.772 0.228 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.772 0.228 0.000
M62 Other disorders of muscle
0.772 0.228 0.000
D64.8 Other specified anaemias
0.772 0.228 0.000
H02.5 Other disorders affecting eyelid function
0.771 0.229 0.000
E03.8 Other specified hypothyroidism
0.771 0.229 0.000
E24 Cushing's syndrome
0.771 0.229 0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.770 0.230 0.000
E14.5 With peripheral circulatory complications
0.769 0.231 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.769 0.231 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.768 0.232 0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)
0.768 0.232 0.000
M00-M03 Infectious arthropathies
0.768 0.232 0.000
Y54.4 Loop [high-ceiling] diuretics
0.767 0.233 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.767 0.233 0.000
H60-H62 Diseases of external ear
0.767 0.233 0.000
E11.8 With unspecified complications
0.767 0.233 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.766 0.234 0.000
H34.1 Central retinal artery occlusion
0.766 0.234 0.000
M24.6 Ankylosis of joint
0.766 0.234 0.000
D04 Carcinoma in situ of skin
0.765 0.235 0.000
L94.0 Localised scleroderma [morphea]
0.765 0.235 0.000
N25-N29 Other disorders of kidney and ureter
0.759 0.236 0.005
L93.0 Discoid lupus erythematosus
0.763 0.237 0.000
L94.9 Localised connective tissue disorder, unspecified
0.763 0.237 0.000
V23.4 Driver injured in traffic accident
0.763 0.237 0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.762 0.238 0.000
Q00-Q07 Congenital malformations of the nervous system
0.761 0.239 0.000
D69.9 Haemorrhagic condition, unspecified
0.761 0.239 0.000
M24.2 Disorder of ligament
0.761 0.239 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.760 0.240 0.000
C92.0 Acute myeloid leukaemia
0.759 0.241 0.000
L83 Acanthosis nigricans
0.758 0.242 0.000
H43.8 Other disorders of vitreous body
0.758 0.242 0.000
H35.4 Peripheral retinal degeneration
0.757 0.243 0.000
M34.8 Other forms of systemic sclerosis
0.757 0.243 0.000
E11.2 With renal complications
0.757 0.243 0.000
E22 Hyperfunction of pituitary gland
0.757 0.243 0.000
L40-L45 Papulosquamous disorders
0.755 0.243 0.002
H02.0 Entropion and trichiasis of eyelid
0.757 0.243 0.000
C04.9 Floor of mouth, unspecified
0.756 0.243 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.757 0.243 0.000
C16.6 Greater curvature of stomach, unspecified
0.756 0.243 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.756 0.244 0.000
D80.1 Nonfamilial hypogammaglobulinaemia
0.756 0.244 0.000
W05 Fall involving wheelchair
0.756 0.244 0.000
V90-V94 Water transport accidents
0.755 0.245 0.000
H05.8 Other disorders of orbit
0.755 0.245 0.000
C16.8 Overlapping lesion of stomach
0.755 0.245 0.000
M20.4 Other hammer toe(s) (acquired)
0.000 0.246 0.754
H04 Disorders of lachrymal system
0.754 0.246 0.000
I62 Other nontraumatic intracranial haemorrhage
0.754 0.246 0.000
D72 Other disorders of white blood cells
0.753 0.247 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.753 0.247 0.000
N03 Chronic nephritic syndrome
0.752 0.248 0.000
Y54.5 Other diuretics
0.751 0.249 0.000
M24.0 Loose body in joint
0.750 0.250 0.000
K90.8 Other intestinal malabsorption
0.750 0.250 0.000
L95.8 Other vasculitis limited to skin
0.750 0.250 0.000
I77.8 Other specified disorders of arteries and arterioles
0.749 0.251 0.000
I77.2 Rupture of artery
0.749 0.251 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.749 0.251 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.749 0.251 0.000
M17.5 Other secondary gonarthrosis
0.748 0.252 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.748 0.252 0.000
B36 Other superficial mycoses
0.747 0.253 0.000
G56.9 Mononeuropathy of upper limb, unspecified
0.747 0.253 0.000
R39 Other symptoms and signs involving the urinary system
0.000 0.253 0.747
Q44.6 Cystic disease of liver
0.747 0.253 0.000
B15-B19 Viral hepatitis
0.745 0.255 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.745 0.255 0.000
C10 Malignant neoplasm of oropharynx
0.745 0.255 0.000
D73.5 Infarction of spleen
0.744 0.256 0.000
V01-V09 Pedestrian injured in transport accident
0.744 0.256 0.000
M15.4 Erosive (osteo)arthrosis
0.743 0.257 0.000
E20 Hypoparathyroidism
0.743 0.257 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.743 0.257 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.743 0.257 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.743 0.257 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.743 0.257 0.000
C03 Malignant neoplasm of gum
0.743 0.257 0.000
Q60-Q64 Congenital malformations of the urinary system
0.742 0.258 0.000
M81.9 Osteoporosis, unspecified
0.741 0.259 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.741 0.259 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.740 0.260 0.000
A15-A19 Tuberculosis
0.739 0.261 0.000
L81 Other disorders of pigmentation
0.737 0.263 0.000
A65-A69 Other spirochaetal diseases
0.736 0.264 0.000
N18.1 Chronic kidney disease, stage 1
0.736 0.264 0.000
D53 Other nutritional anaemias
0.736 0.264 0.000
E28 Ovarian dysfunction
0.736 0.264 0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)
0.734 0.266 0.000
L27 Dermatitis due to substances taken internally
0.734 0.266 0.000
N18.8 Other chronic renal failure
0.733 0.267 0.000
C34.3 Lower lobe, bronchus or lung
0.733 0.267 0.000
K72.0 Acute and subacute hepatic failure
0.733 0.267 0.000
E23 Hypofunction and other disorders of pituitary gland
0.733 0.267 0.000
I65.0 Occlusion and stenosis of vertebral artery
0.733 0.267 0.000
M34.9 Systemic sclerosis, unspecified
0.733 0.267 0.000
D61.1 Drug-induced aplastic anaemia
0.732 0.268 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.731 0.269 0.000
E21.3 Hyperparathyroidism, unspecified
0.731 0.269 0.000
B37.2 Candidiasis of skin and nail
0.730 0.270 0.000
N18.5 Chronic kidney disease, stage 5
0.729 0.271 0.000
Q50-Q56 Congenital malformations of genital organs
0.729 0.271 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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