TreeWAS – Variant ID: rs16899661

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Z88.0 Personal history of allergy to penicillin	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
K90.0 Coeliac disease	0.000	0.000	1.000
L40.9 Psoriasis, unspecified	1.000	0.000	0.000
L40 Psoriasis	1.000	0.000	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	1.000	0.000	0.000
L40-L45 Papulosquamous disorders	1.000	0.000	0.000
Chapter XX External causes of morbidity and mortality	0.999	0.001	0.000
Chapter V Mental and behavioural disorders	0.999	0.001	0.000
F30-F39 Mood [affective] disorders	0.995	0.005	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.992	0.008	0.000
F31 Bipolar affective disorder	0.991	0.009	0.000
Chapter II Neoplasms	0.988	0.012	0.000
C44.3 Skin of other and unspecified parts of face	0.988	0.012	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.986	0.014	0.000
C44 Other malignant neoplasms of skin	0.985	0.015	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.982	0.018	0.000
F31.9 Bipolar affective disorder, unspecified	0.971	0.029	0.000
Chapter I Certain infectious and parasitic diseases	0.962	0.038	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.958	0.042	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.957	0.043	0.000
W20-W49 Exposure to inanimate mechanical forces	0.948	0.052	0.000
L40.5 Arthropathic psoriasis	0.931	0.069	0.000
Chapter VII Diseases of the eye and adnexa	0.926	0.074	0.000
L20-L30 Dermatitis and eczema	0.925	0.075	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.919	0.081	0.000
A30-A49 Other bacterial diseases	0.915	0.085	0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.900	0.100	0.000
F33 Recurrent depressive disorder	0.898	0.102	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.892	0.108	0.000
H53-H54 Visual disturbances and blindness	0.885	0.115	0.000
F03 Unspecified dementia	0.882	0.118	0.000
W22 Striking against or struck by other objects	0.880	0.120	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.879	0.121	0.000
B25-B34 Other viral diseases	0.862	0.138	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.858	0.142	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.853	0.147	0.000
X20-X29 Contact with venomous animals and plants	0.849	0.151	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.848	0.152	0.000
L29 Pruritus	0.848	0.152	0.000
S80-S89 Injuries to the knee and lower leg	0.848	0.152	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.845	0.155	0.000
A49 Bacterial infection of unspecified site	0.844	0.156	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.844	0.156	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.843	0.157	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.842	0.158	0.000
H54 Blindness and low vision	0.842	0.158	0.000
B15-B19 Viral hepatitis	0.840	0.160	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.836	0.164	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.832	0.168	0.000
W22.9 Unspecified place	0.831	0.169	0.000
L57 Skin changes due to chronic exposure to nonionising radiation	0.828	0.172	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.828	0.172	0.000
C73 Malignant neoplasm of thyroid gland	0.823	0.177	0.000
H10-H13 Disorders of conjunctiva	0.822	0.178	0.000
Y52 Agents primarily affecting the cardiovascular system	0.821	0.179	0.000
C44.4 Skin of scalp and neck	0.820	0.180	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.813	0.187	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.811	0.188	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.808	0.192	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.807	0.193	0.000
C44.5 Skin of trunk	0.803	0.196	0.000
L29.0 Pruritus ani	0.800	0.200	0.000
F33.9 Recurrent depressive disorder, unspecified	0.799	0.201	0.000
H54.0 Blindness, both eyes	0.799	0.201	0.000
A49.0 Staphylococcal infection, unspecified	0.792	0.208	0.000
B99-B99 Other infectious diseases	0.792	0.208	0.000
L57.0 Actinic keratosis	0.791	0.209	0.000
F80-F89 Disorders of psychological development	0.791	0.209	0.000
V40-V49 Car occupant injured in transport accident	0.790	0.210	0.000
H55-H59 Other disorders of eye and adnexa	0.789	0.211	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.789	0.211	0.000
B34 Viral infection of unspecified site	0.789	0.211	0.000
H54.7 Unspecified visual loss	0.785	0.215	0.000
L40.0 Psoriasis vulgaris	0.783	0.217	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.783	0.217	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.781	0.219	0.000
S70-S79 Injuries to the hip and thigh	0.781	0.219	0.000
C51-C58 Malignant neoplasms of female genital organs	0.781	0.219	0.000
F34 Persistent mood [affective] disorders	0.780	0.220	0.000
Chapter VI Diseases of the nervous system	0.779	0.221	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.778	0.222	0.000
T79-T79 Certain early complications of trauma	0.777	0.223	0.000
Y40 Systemic antibiotics	0.774	0.226	0.000
Y44 Agents primarily affecting blood constituents	0.773	0.227	0.000
A40 Streptococcal septicaemia	0.771	0.229	0.000
X60-X84 Intentional self-harm	0.768	0.232	0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.766	0.234	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.765	0.235	0.000
S50-S59 Injuries to the elbow and forearm	0.764	0.235	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.764	0.236	0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.764	0.236	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.764	0.236	0.000
C64-C68 Malignant neoplasms of urinary tract	0.764	0.236	0.000
S40-S49 Injuries to the shoulder and upper arm	0.762	0.238	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.755	0.245	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.753	0.247	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.752	0.248	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.751	0.249	0.000
Y00-Y09 Assault	0.751	0.249	0.000
B50-B64 Protozoal diseases	0.749	0.251	0.000
W00-W19 Falls	0.748	0.252	0.000
A80-A89 Viral infections of the central nervous system	0.745	0.255	0.000
D45 Polycythaemia vera	0.743	0.257	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.743	0.257	0.000
X23 Contact with hornets, wasps and bees	0.741	0.259	0.000
W25 Contact with sharp glass	0.741	0.259	0.000
T63 Toxic effect of contact with venomous animals	0.740	0.260	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.739	0.261	0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.736	0.263	0.000
H57 Other disorders of eye and adnexa	0.736	0.264	0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.733	0.267	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.731	0.269	0.000
B65-B83 Helminthiases	0.730	0.270	0.000
F00 Dementia in Alzheimer's disease	0.728	0.272	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.727	0.273	0.000
F02 Dementia in other diseases classified elsewhere	0.727	0.273	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.727	0.273	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.726	0.274	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.726	0.274	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.724	0.276	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.723	0.277	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.723	0.277	0.000
W49 Exposure to other and unspecified inanimate mechanical forces	0.722	0.278	0.000
H11 Other disorders of conjunctiva	0.722	0.278	0.000
S10-S19 Injuries to the neck	0.722	0.278	0.000
T66-T78 Other and unspecified effects of external causes	0.721	0.278	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.721	0.279	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.721	0.279	0.000
D00-D09 In situ neoplasms	0.719	0.281	0.000
T39.0 Salicylates	0.719	0.281	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.719	0.281	0.000
C44.2 Skin of ear and external auricular canal	0.718	0.282	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.718	0.282	0.000
B34.9 Viral infection, unspecified	0.718	0.282	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
L40.8 Other psoriasis	0.717	0.283	0.000
L40.4 Guttate psoriasis	0.717	0.283	0.000
L40.3 Pustulosis palmaris et plantaris	0.717	0.283	0.000
L40.2 Acrodermatitis continua	0.717	0.283	0.000
L40.1 Generalised pustular psoriasis	0.717	0.283	0.000
L10-L14 Bullous disorders	0.717	0.283	0.000
L44 Other papulosquamous disorders	0.717	0.283	0.000
L41 Parapsoriasis	0.717	0.283	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.717	0.283	0.000
L42 Pityriasis rosea	0.717	0.283	0.000
F01 Vascular dementia	0.717	0.283	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.716	0.283	0.000
Y35-Y36 Legal intervention and operations of war	0.716	0.283	0.000
Y10-Y34 Event of undetermined intent	0.716	0.283	0.000
X85-X99 Assault	0.716	0.283	0.000
X50-X57 Overexertion, travel and privation	0.716	0.283	0.000
X30-X39 Exposure to forces of nature	0.716	0.283	0.000
X10-X19 Contact with heat and hot substances	0.716	0.283	0.000
X00-X09 Exposure to smoke, fire and flames	0.716	0.283	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.716	0.283	0.000
W75-W84 Other accidental threats to breathing	0.716	0.283	0.000
W65-W74 Accidental drowning and submersion	0.716	0.283	0.000
W50-W64 Exposure to animate mechanical forces	0.716	0.283	0.000
V98-V99 Other and unspecified transport accidents	0.716	0.283	0.000
V95-V97 Air and space transport accidents	0.716	0.283	0.000
V90-V94 Water transport accidents	0.716	0.283	0.000
V80-V89 Other land transport accidents	0.716	0.283	0.000
V70-V79 Bus occupant injured in transport accident	0.716	0.283	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.716	0.283	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.716	0.283	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.716	0.283	0.000
V01-V09 Pedestrian injured in transport accident	0.716	0.283	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.716	0.284	0.000
F70-F79 Mental retardation	0.716	0.284	0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.716	0.284	0.000
V20-V29 Motorcycle rider injured in transport accident	0.715	0.285	0.000
F38 Other mood [affective] disorders	0.714	0.286	0.000
F30 Manic episode	0.714	0.286	0.000
F39 Unspecified mood [affective] disorder	0.714	0.286	0.000
L28 Lichen simplex chronicus and prurigo	0.713	0.287	0.000
F05 Delirium, not induced by alcohol and other psychoactive substances	0.712	0.288	0.000
L27 Dermatitis due to substances taken internally	0.712	0.288	0.000
Y95 Nosocomial condition	0.712	0.288	0.000
T33-T35 Frostbite	0.711	0.289	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.711	0.289	0.000
T00-T07 Injuries involving multiple body regions	0.711	0.289	0.000
F31.8 Other bipolar affective disorders	0.710	0.290	0.000
F31.7 Bipolar affective disorder, currently in remission	0.710	0.290	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.710	0.290	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.710	0.290	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.710	0.290	0.000
C44.7 Skin of lower limb, including hip	0.709	0.291	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.709	0.291	0.000
H18 Other disorders of cornea	0.708	0.292	0.000
H53 Visual disturbances	0.707	0.293	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.707	0.293	0.000
C44.9 Malignant neoplasm of skin, unspecified	0.707	0.293	0.000
C44.8 Overlapping lesion of skin	0.707	0.293	0.000
W29 Contact with other powered hand tools and household machinery	0.705	0.295	0.000
Y42.7 Androgens and anabolic congeners	0.705	0.295	0.000
Y57 Other and unspecified drugs and medicaments	0.705	0.295	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.704	0.296	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.704	0.296	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.704	0.296	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.704	0.296	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.704	0.296	0.000
T36 Poisoning by systemic antibiotics	0.704	0.296	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.703	0.297	0.000
W44 Foreign body entering into or through eye or natural orifice	0.702	0.298	0.000
L60-L75 Disorders of skin appendages	0.699	0.301	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.698	0.302	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.698	0.302	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.696	0.304	0.000
G90-G99 Other disorders of the nervous system	0.696	0.304	0.000
B17 Other acute viral hepatitis	0.693	0.307	0.000
T45.0 Antiallergic and antiemetic drugs	0.691	0.309	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.690	0.310	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.690	0.310	0.000
A75-A79 Rickettsioses	0.690	0.310	0.000
A70-A74 Other diseases caused by chlamydiae	0.690	0.310	0.000
A65-A69 Other spirochaetal diseases	0.690	0.310	0.000
A20-A28 Certain zoonotic bacterial diseases	0.690	0.310	0.000
A15-A19 Tuberculosis	0.690	0.310	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.690	0.310	0.000
Y59 Other and unspecified vaccines and biological substances	0.687	0.313	0.000
Y58 Bacterial vaccines	0.687	0.313	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.687	0.313	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.687	0.313	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.687	0.313	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.687	0.313	0.000
Y48 Anaesthetics and therapeutic gases	0.687	0.313	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.687	0.313	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.687	0.313	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.686	0.314	0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.686	0.314	0.000
F09 Unspecified organic or symptomatic mental disorder	0.686	0.314	0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.686	0.314	0.000
Y84.2 Radiological procedure and radiotherapy	0.685	0.315	0.000
A48 Other bacterial diseases, not elsewhere classified	0.685	0.315	0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.684	0.316	0.000
C11 Malignant neoplasm of nasopharynx	0.684	0.316	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.682	0.318	0.000
S20-S29 Injuries to the thorax	0.681	0.319	0.000
C01 Malignant neoplasm of base of tongue	0.681	0.319	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.681	0.319	0.000
W46 Contact with hypodermic needle	0.680	0.320	0.000
W45 Foreign body or object entering through skin	0.680	0.320	0.000
W43 Exposure to vibration	0.680	0.320	0.000
W42 Exposure to noise	0.680	0.320	0.000
W41 Exposure to high-pressure jet	0.680	0.320	0.000
W40 Explosion of other materials	0.680	0.320	0.000
W39 Discharge of firework	0.680	0.320	0.000
W38 Explosion and rupture of other specified pressurised devices	0.680	0.320	0.000
W37 Explosion and rupture of pressurised tyre, pipe or hose	0.680	0.320	0.000
W36 Explosion and rupture of gas cylinder	0.680	0.320	0.000
W35 Explosion and rupture of boiler	0.680	0.320	0.000
W34 Discharge from other and unspecified firearms	0.680	0.320	0.000
W33 Rifle, shotgun and larger firearm discharge	0.680	0.320	0.000
W32 Handgun discharge	0.680	0.320	0.000
W31 Contact with other and unspecified machinery	0.680	0.320	0.000
W30 Contact with agricultural machinery	0.680	0.320	0.000
W28 Contact with powered lawn mower	0.680	0.320	0.000
W27 Contact with nonpowered hand tool	0.680	0.320	0.000
W26 Contact with knife, sword or dagger	0.680	0.320	0.000
W24 Contact with lifting and transmission devices, not elsewhere classified	0.680	0.320	0.000
W23 Caught, crushed, jammed or pinched in or between objects	0.680	0.320	0.000
W21 Striking against or struck by sports equipment	0.680	0.320	0.000
W20 Struck by thrown, projected or falling object	0.680	0.320	0.000
S82 Fracture of lower leg, including ankle	0.679	0.321	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.679	0.321	0.000
H15 Disorders of sclera	0.678	0.321	0.000
E10.9 Without complications	0.000	0.323	0.677
T63.4 Venom of other arthropods	0.676	0.324	0.000
F60-F69 Disorders of adult personality and behaviour	0.676	0.324	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.676	0.324	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.675	0.325	0.000
B18 Chronic viral hepatitis	0.675	0.325	0.000
Chapter XXII Codes for special purposes	0.673	0.326	0.000
S90-S99 Injuries to the ankle and foot	0.673	0.327	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.673	0.327	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.673	0.327	0.000
H57.1 Ocular pain	0.671	0.329	0.000
C09 Malignant neoplasm of tonsil	0.670	0.330	0.000
B99 Other and unspecified infectious diseases	0.669	0.331	0.000
Q60-Q64 Congenital malformations of the urinary system	0.668	0.332	0.000
S60-S69 Injuries to the wrist and hand	0.667	0.333	0.000
H17 Corneal scars and opacities	0.665	0.335	0.000
C53 Malignant neoplasm of cervix uteri	0.664	0.336	0.000
L25 Unspecified contact dermatitis	0.663	0.337	0.000
L24 Irritant contact dermatitis	0.663	0.337	0.000
L23 Allergic contact dermatitis	0.663	0.337	0.000
L21 Seborrhoeic dermatitis	0.663	0.337	0.000
L20 Atopic dermatitis	0.663	0.337	0.000
L26 Exfoliative dermatitis	0.663	0.337	0.000
L22 Diaper [napkin] dermatitis	0.663	0.337	0.000
Q50-Q56 Congenital malformations of genital organs	0.662	0.338	0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.661	0.339	0.000
A41 Other septicaemia	0.661	0.339	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.659	0.341	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.659	0.341	0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.659	0.341	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.659	0.341	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.657	0.343	0.000
A44 Bartonellosis	0.656	0.344	0.000
A43 Nocardiosis	0.656	0.344	0.000
A42 Actinomycosis	0.656	0.344	0.000
A39 Meningococcal infection	0.656	0.344	0.000
A37 Whooping cough	0.656	0.344	0.000
A36 Diphtheria	0.656	0.344	0.000
A32 Listeriosis	0.656	0.344	0.000
A31 Infection due to other mycobacteria	0.656	0.344	0.000
A30 Leprosy [Hansen's disease]	0.656	0.344	0.000
A46 Erysipelas	0.656	0.344	0.000
A38 Scarlet fever	0.656	0.344	0.000
A35 Other tetanus	0.656	0.344	0.000
A34 Obstetrical tetanus	0.656	0.344	0.000
A33 Tetanus neonatorum	0.656	0.344	0.000
Q80-Q89 Other congenital malformations	0.656	0.344	0.000
Y40.0 Penicillins	0.655	0.345	0.000
S80 Superficial injury of lower leg	0.655	0.345	0.000
Y60.0 During surgical operation	0.653	0.347	0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.653	0.347	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.653	0.347	0.000
L29.2 Pruritus vulvae	0.651	0.349	0.000
T42.4 Benzodiazepines	0.650	0.350	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.650	0.350	0.000
H10 Conjunctivitis	0.648	0.352	0.000
L30 Other dermatitis	0.647	0.353	0.000
S51 Open wound of forearm	0.647	0.353	0.000
G35 Multiple sclerosis	0.647	0.353	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.647	0.353	0.000
T46.1 Calcium-channel blockers	0.646	0.354	0.000
M05-M14 Inflammatory polyarthropathies	0.645	0.355	0.000
L59 Other disorders of skin and subcutaneous tissue related to radiation	0.645	0.355	0.000
L58 Radiodermatitis	0.645	0.355	0.000
L56 Other acute skin changes due to ultraviolet radiation	0.645	0.355	0.000
L55 Sunburn	0.645	0.355	0.000
D37.9 Digestive organ, unspecified	0.645	0.355	0.000
D06 Carcinoma in situ of cervix uteri	0.645	0.355	0.000
F33.8 Other recurrent depressive disorders	0.644	0.356	0.000
F33.4 Recurrent depressive disorder, currently in remission	0.644	0.356	0.000
F33.0 Recurrent depressive disorder, current episode mild	0.644	0.356	0.000
H20 Iridocyclitis	0.644	0.356	0.000
C50-C50 Malignant neoplasm of breast	0.643	0.357	0.000
D46 Myelodysplastic syndromes	0.643	0.357	0.000
S83.6 Sprain and strain of other and unspecified parts of knee	0.642	0.358	0.000
G30-G32 Other degenerative diseases of the nervous system	0.642	0.358	0.000
Y44.2 Anticoagulants	0.641	0.359	0.000
D37.1 Stomach	0.640	0.360	0.000
C75 Malignant neoplasm of other endocrine glands and related structures	0.640	0.360	0.000
C74 Malignant neoplasm of adrenal gland	0.640	0.360	0.000
V49 Car occupant injured in other and unspecified transport accidents	0.640	0.360	0.000
V10-V19 Pedal cyclist injured in transport accident	0.638	0.361	0.000
F99-F99 Unspecified mental disorder	0.637	0.363	0.000
B15 Acute hepatitis A	0.636	0.364	0.000
A40.1 Septicaemia due to streptococcus, group B	0.636	0.364	0.000
F40 Phobic anxiety disorders	0.635	0.365	0.000
X23.9 Unspecified place	0.634	0.366	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.633	0.366	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.632	0.368	0.000
T40.2 Other opioids	0.632	0.368	0.000
W22.8 Other specified place	0.631	0.369	0.000
W22.6 Industrial and construction area	0.631	0.369	0.000
W22.4 Street and highway	0.631	0.369	0.000
W22.0 Home	0.631	0.369	0.000
W22.7 Farm	0.631	0.369	0.000
W22.5 Trade and service area	0.631	0.369	0.000
W22.3 Sports and athletics area	0.631	0.369	0.000
W22.2 School, other institution and public administrative area	0.631	0.369	0.000
W22.1 Residential institution	0.631	0.369	0.000
A49.9 Bacterial infection, unspecified	0.630	0.369	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.630	0.370	0.000
Q35-Q37 Cleft lip and cleft palate	0.630	0.370	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.630	0.370	0.000
F81 Specific developmental disorders of scholastic skills	0.628	0.372	0.000
Y49.2 Other and unspecified antidepressants	0.626	0.374	0.000
F06.7 Mild cognitive disorder	0.626	0.374	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.626	0.374	0.000
F34.1 Dysthymia	0.625	0.375	0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.625	0.375	0.000
B25 Cytomegaloviral disease	0.625	0.375	0.000
B34.8 Other viral infections of unspecified site	0.623	0.376	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.623	0.377	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.623	0.377	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.622	0.378	0.000
S86 Injury of muscle and tendon at lower leg level	0.621	0.379	0.000
B33 Other viral diseases, not elsewhere classified	0.618	0.382	0.000
B30 Viral conjunctivitis	0.618	0.382	0.000
B27 Infectious mononucleosis	0.618	0.382	0.000
B26 Mumps	0.618	0.382	0.000
D37.4 Colon	0.618	0.382	0.000
C64 Malignant neoplasm of kidney, except renal pelvis	0.617	0.383	0.000
Y84.6 Urinary catheterisation	0.617	0.383	0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards	0.616	0.384	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.615	0.384	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.615	0.385	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.615	0.385	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.615	0.385	0.000
T42.3 Barbiturates	0.615	0.385	0.000
T42.2 Succinimides and oxazolidinediones	0.615	0.385	0.000
T42.1 Iminostilbenes	0.615	0.385	0.000
T42.0 Hydantoin derivatives	0.615	0.385	0.000
S82.2 Fracture of shaft of tibia	0.614	0.386	0.000
T43.2 Other and unspecified antidepressants	0.614	0.386	0.000
E10 Insulin-dependent diabetes mellitus	0.001	0.388	0.611
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.611	0.389	0.000
C13 Malignant neoplasm of hypopharynx	0.611	0.389	0.000
C10 Malignant neoplasm of oropharynx	0.611	0.389	0.000
C08 Malignant neoplasm of other and unspecified major salivary glands	0.611	0.389	0.000
C06 Malignant neoplasm of other and unspecified parts of mouth	0.611	0.389	0.000
C05 Malignant neoplasm of palate	0.611	0.389	0.000
C04 Malignant neoplasm of floor of mouth	0.611	0.389	0.000
C03 Malignant neoplasm of gum	0.611	0.389	0.000
C00 Malignant neoplasm of lip	0.611	0.389	0.000
C12 Malignant neoplasm of pyriform sinus	0.611	0.389	0.000
C07 Malignant neoplasm of parotid gland	0.611	0.389	0.000
S79 Other and unspecified injuries of hip and thigh	0.611	0.389	0.000
D47.2 Monoclonal gammopathy	0.611	0.389	0.000
X68 Intentional self-poisoning by and exposure to pesticides	0.610	0.390	0.000
Y40.3 Macrolides	0.609	0.391	0.000
D43.0 Brain, supratentorial	0.609	0.391	0.000
G99 Other disorders of nervous system in diseases classified elsewhere	0.609	0.391	0.000
X29 Contact with unspecified venomous animal or plant	0.609	0.391	0.000
X28 Contact with other specified venomous plants	0.609	0.391	0.000
X27 Contact with other specified venomous animals	0.609	0.391	0.000
X26 Contact with venomous marine animals and plants	0.609	0.391	0.000
X25 Contact with other specified venomous arthropods	0.609	0.391	0.000
X24 Contact with centipedes and venomous millipedes (tropical)	0.609	0.391	0.000
X22 Contact with scorpions	0.609	0.391	0.000
X21 Contact with venomous spiders	0.609	0.391	0.000
X20 Contact with venomous snakes and lizards	0.609	0.391	0.000
F22 Persistent delusional disorders	0.608	0.392	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.608	0.392	0.000
L29.8 Other pruritus	0.608	0.392	0.000
L29.3 Anogenital pruritus, unspecified	0.608	0.392	0.000
L29.1 Pruritus scroti	0.608	0.392	0.000
A49.8 Other bacterial infections of unspecified site	0.608	0.392	0.000
C71 Malignant neoplasm of brain	0.608	0.392	0.000
S88 Traumatic amputation of lower leg	0.608	0.392	0.000
S87 Crushing injury of lower leg	0.608	0.392	0.000
S85 Injury of blood vessels at lower leg level	0.608	0.392	0.000
S84 Injury of nerves at lower leg level	0.608	0.392	0.000
S70 Superficial injury of hip and thigh	0.608	0.392	0.000
H53.1 Subjective visual disturbances	0.607	0.392	0.000
T39.1 4-Aminophenol derivatives	0.607	0.393	0.000
Q23 Congenital malformations of aortic and mitral valves	0.607	0.393	0.000
A49.3 Mycoplasma infection, unspecified	0.605	0.394	0.000
A49.2 Haemophilus influenzae infection, unspecified	0.605	0.394	0.000
Y65 Other misadventures during surgical and medical care	0.605	0.395	0.000
Y64 Contaminated medical or biological substances	0.605	0.395	0.000
Y63 Failure in dosage during surgical and medical care	0.605	0.395	0.000
Y62 Failure of sterile precautions during surgical and medical care	0.605	0.395	0.000
Y61 Foreign object accidentally left in body during surgical and medical care	0.605	0.395	0.000
Y69 Unspecified misadventure during surgical and medical care	0.605	0.395	0.000
Y66 Nonadministration of surgical and medical care	0.605	0.395	0.000
H16 Keratitis	0.605	0.395	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.605	0.395	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.605	0.395	0.000
T39.4 Antirheumatics, not elsewhere classified	0.605	0.395	0.000
T39.2 Pyrazolone derivatives	0.605	0.395	0.000
C55 Malignant neoplasm of uterus, part unspecified	0.604	0.395	0.000
G37 Other demyelinating diseases of central nervous system	0.604	0.396	0.000
H54.6 Unqualified visual loss, one eye	0.604	0.396	0.000
H54.5 Low vision, one eye	0.604	0.396	0.000
H54.3 Unqualified visual loss, both eyes	0.604	0.396	0.000
H54.2 Low vision, both eyes	0.604	0.396	0.000
H54.1 Blindness, one eye, low vision, other eye	0.604	0.396	0.000
B19 Unspecified viral hepatitis	0.602	0.398	0.000
B16 Acute hepatitis B	0.602	0.398	0.000
Y42.5 Other oestrogens and progestogens	0.601	0.399	0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.601	0.399	0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.600	0.400	0.000
W17 Other fall from one level to another	0.598	0.402	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.598	0.402	0.000
S40 Superficial injury of shoulder and upper arm	0.598	0.402	0.000
C69 Malignant neoplasm of eye and adnexa	0.597	0.403	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.597	0.403	0.000
B50 Plasmodium falciparum malaria	0.597	0.403	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.596	0.403	0.000
Y91 Evidence of alcohol involvement determined by level of intoxication	0.596	0.403	0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level	0.596	0.403	0.000
Y98 Lifestyle-related condition	0.596	0.403	0.000
Y97 Environmental-pollution-related condition	0.596	0.403	0.000
Y96 Work-related condition	0.596	0.403	0.000
H18.2 Other corneal oedema	0.596	0.404	0.000
M05 Seropositive rheumatoid arthritis	0.596	0.404	0.000
S41 Open wound of shoulder and upper arm	0.595	0.405	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.594	0.406	0.000
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified	0.594	0.406	0.000
L57.5 Actinic granuloma	0.594	0.406	0.000
L57.4 Cutis laxa senilis	0.594	0.406	0.000
L57.3 Poikiloderma of Civatte	0.594	0.406	0.000
L57.2 Cutis rhomboidalis nuchae	0.594	0.406	0.000
L57.1 Actinic reticuloid	0.594	0.406	0.000
T65 Toxic effect of other and unspecified substances	0.593	0.406	0.000
T62 Toxic effect of other noxious substances eaten as food	0.593	0.406	0.000
T61 Toxic effect of noxious substances eaten as seafood	0.593	0.406	0.000
T60 Toxic effect of pesticides	0.593	0.406	0.000
T59 Toxic effect of other gases, fumes and vapours	0.593	0.406	0.000
T57 Toxic effect of other inorganic substances	0.593	0.406	0.000
T56 Toxic effect of metals	0.593	0.406	0.000
T54 Toxic effect of corrosive substances	0.593	0.406	0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.593	0.406	0.000
T52 Toxic effect of organic solvents	0.593	0.406	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations