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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs7558007
log Bayes Factor = 7.10506
Chromosome 2   position 58,350,504  (GRCh37) Explore rs7558007 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Z92 Personal history of medical treatment
0.999 0.001 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.998 0.002 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.997 0.003 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.995 0.005 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.994 0.006 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.992 0.008 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.991 0.009 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.987 0.013 0.000
E70-E90 Metabolic disorders
0.986 0.014 0.000
Chapter IX Diseases of the circulatory system
0.984 0.016 0.000
I50 Heart failure
0.977 0.023 0.000
E83 Disorders of mineral metabolism
0.975 0.025 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.975 0.025 0.000
I30-I52 Other forms of heart disease
0.974 0.026 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.973 0.027 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.972 0.028 0.000
I50.0 Congestive heart failure
0.972 0.028 0.000
E20-E35 Disorders of other endocrine glands
0.969 0.031 0.000
Z90.5 Acquired absence of kidney
0.963 0.037 0.000
Z80 Family history of malignant neoplasm
0.958 0.042 0.000
I20-I25 Ischaemic heart diseases
0.955 0.045 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.955 0.045 0.000
Y83.3 Surgical operation with formation of external stoma
0.953 0.047 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.952 0.048 0.000
I25 Chronic ischaemic heart disease
0.952 0.048 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.949 0.051 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.949 0.051 0.000
Z42 Follow-up care involving plastic surgery
0.946 0.054 0.000
E83.5 Disorders of calcium metabolism
0.941 0.059 0.000
E00-E07 Disorders of thyroid gland
0.941 0.059 0.000
I50.9 Heart failure, unspecified
0.939 0.061 0.000
Z42.1 Follow-up care involving plastic surgery of breast
0.938 0.062 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.937 0.063 0.000
Z83 Family history of other specific disorders
0.935 0.065 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.933 0.067 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.931 0.069 0.000
Y43 Primarily systemic agents
0.927 0.073 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.927 0.073 0.000
E27 Other disorders of adrenal gland
0.925 0.075 0.000
I05-I09 Chronic rheumatic heart diseases
0.925 0.075 0.000
Z80.9 Family history of malignant neoplasm, unspecified
0.923 0.077 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.922 0.078 0.000
Z80.3 Family history of malignant neoplasm of breast
0.917 0.083 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.915 0.085 0.000
S70-S79 Injuries to the hip and thigh
0.911 0.089 0.000
S40-S49 Injuries to the shoulder and upper arm
0.907 0.093 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.906 0.094 0.000
D69 Purpura and other haemorrhagic conditions
0.904 0.096 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.902 0.098 0.000
I50.1 Left ventricular failure
0.902 0.098 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.902 0.098 0.000
E04 Other non-toxic goitre
0.898 0.102 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.895 0.105 0.000
E87.5 Hyperkalaemia
0.895 0.105 0.000
Z57 Occupational exposure to risk-factors
0.895 0.105 0.000
Z83.3 Family history of diabetes mellitus
0.892 0.108 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.886 0.114 0.000
I08 Multiple valve diseases
0.883 0.117 0.000
D69.6 Thrombocytopenia, unspecified
0.882 0.118 0.000
E40-E46 Malnutrition
0.881 0.119 0.000
E83.1 Disorders of iron metabolism
0.880 0.120 0.000
E87.0 Hyperosmolality and hypernatraemia
0.879 0.121 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.879 0.121 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.877 0.123 0.000
Z42.0 Follow-up care involving plastic surgery of head and neck
0.876 0.124 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.872 0.128 0.000
S72 Fracture of femur
0.872 0.128 0.000
E27.1 Primary adrenocortical insufficiency
0.871 0.129 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
0.870 0.130 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.870 0.130 0.000
I31 Other diseases of pericardium
0.867 0.133 0.000
Y43.3 Other antineoplastic drugs
0.866 0.134 0.000
Z40 Prophylactic surgery
0.865 0.135 0.000
Chapter XXII Codes for special purposes
0.863 0.137 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.863 0.137 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.863 0.137 0.000
I08.0 Disorders of both mitral and aortic valves
0.857 0.143 0.000
E83.4 Disorders of magnesium metabolism
0.854 0.146 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.853 0.147 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.850 0.150 0.000
Z88.5 Personal history of allergy to narcotic agent
0.844 0.156 0.000
Z90.0 Acquired absence of part of head and neck
0.844 0.156 0.000
Y45.0 Opioids and related analgesics
0.839 0.161 0.000
S72.0 Fracture of neck of femur
0.839 0.161 0.000
Chapter VIII Diseases of the ear and mastoid process
0.836 0.164 0.000
E88 Other metabolic disorders
0.835 0.165 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.835 0.165 0.000
V10-V19 Pedal cyclist injured in transport accident
0.833 0.166 0.000
E04.9 Non-toxic goitre, unspecified
0.832 0.168 0.000
S10-S19 Injuries to the neck
0.831 0.169 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.829 0.171 0.000
Z57.5 Occupational exposure to toxic agents in other industries
0.827 0.173 0.000
E04.2 Non-toxic multinodular goitre
0.826 0.174 0.000
T66-T78 Other and unspecified effects of external causes
0.823 0.177 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.821 0.179 0.000
Z97 Presence of other devices
0.819 0.181 0.000
E22 Hyperfunction of pituitary gland
0.818 0.182 0.000
H65-H75 Diseases of middle ear and mastoid
0.817 0.183 0.000
S72.00 Fracture of neck of femur (closed)
0.816 0.184 0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms
0.814 0.186 0.000
Z83.4 Family history of other endocrine, nutritional and metabolic diseases
0.811 0.189 0.000
E50-E64 Other nutritional deficiencies
0.805 0.195 0.000
Z88.6 Personal history of allergy to analgesic agent
0.803 0.197 0.000
Y60.0 During surgical operation
0.802 0.198 0.000
Z93 Artificial opening status
0.800 0.200 0.000
I34 Nonrheumatic mitral valve disorders
0.800 0.200 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.800 0.200 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.796 0.204 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.796 0.204 0.000
E46 Unspecified protein-energy malnutrition
0.796 0.204 0.000
Z44 Fitting and adjustment of external prosthetic device
0.795 0.205 0.000
I36 Nonrheumatic tricuspid valve disorders
0.792 0.208 0.000
Z90.8 Acquired absence of other organs
0.792 0.208 0.000
E16 Other disorders of pancreatic internal secretion
0.789 0.211 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.788 0.212 0.000
Z97.4 Presence of external hearing-aid
0.786 0.214 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.786 0.214 0.000
E06 Thyroiditis
0.784 0.216 0.000
V40-V49 Car occupant injured in transport accident
0.784 0.216 0.000
Y43.4 Immunosuppressive agents
0.782 0.218 0.000
Z58 Problems related to physical environment
0.779 0.221 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.776 0.224 0.000
Chapter I Certain infectious and parasitic diseases
0.776 0.224 0.000
W50-W64 Exposure to animate mechanical forces
0.774 0.226 0.000
T80.2 Infections following infusion, transfusion and therapeutic injection
0.774 0.226 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.773 0.227 0.000
I31.3 Pericardial effusion (noninflammatory)
0.772 0.228 0.000
E23 Hypofunction and other disorders of pituitary gland
0.770 0.230 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.768 0.232 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.767 0.232 0.000
Z41 Procedures for purposes other than remedying health state
0.767 0.233 0.000
Z84 Family history of other conditions
0.767 0.233 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.767 0.233 0.000
I24 Other acute ischaemic heart diseases
0.766 0.234 0.000
Z90.3 Acquired absence of part of stomach
0.766 0.234 0.000
Y00-Y09 Assault
0.766 0.234 0.000
Z63 Other problems related to primary support group, including family circumstances
0.765 0.235 0.000
Y42.5 Other oestrogens and progestogens
0.765 0.235 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.761 0.239 0.000
T79-T79 Certain early complications of trauma
0.760 0.240 0.000
Z90.1 Acquired absence of breast(s)
0.759 0.241 0.000
S72.3 Fracture of shaft of femur
0.758 0.242 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.758 0.242 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.757 0.243 0.000
Z49 Care involving dialysis
0.755 0.245 0.000
S40 Superficial injury of shoulder and upper arm
0.755 0.245 0.000
Y60.4 During endoscopic examination
0.753 0.247 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.752 0.248 0.000
I33 Acute and subacute endocarditis
0.752 0.248 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.750 0.250 0.000
I38 Endocarditis, valve unspecified
0.748 0.252 0.000
Y83.9 Surgical procedure, unspecified
0.748 0.252 0.000
W00-W19 Falls
0.748 0.252 0.000
D55-D59 Haemolytic anaemias
0.748 0.252 0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection
0.747 0.253 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.746 0.253 0.000
Q60-Q64 Congenital malformations of the urinary system
0.746 0.254 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.746 0.254 0.000
S41 Open wound of shoulder and upper arm
0.745 0.255 0.000
H73 Other disorders of tympanic membrane
0.745 0.255 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.745 0.255 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.744 0.256 0.000
E27.2 Addisonian crisis
0.743 0.257 0.000
Z43 Attention to artificial openings
0.741 0.259 0.000
Z59 Problems related to housing and economic circumstances
0.741 0.259 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.741 0.259 0.000
Z80.5 Family history of malignant neoplasm of urinary tract
0.740 0.260 0.000
Z92.0 Personal history of contraception
0.739 0.261 0.000
E24 Cushing's syndrome
0.736 0.263 0.000
H66 Suppurative and unspecified otitis media
0.735 0.265 0.000
H74 Other disorders of middle ear and mastoid
0.733 0.267 0.000
I07 Rheumatic tricuspid valve diseases
0.732 0.268 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.731 0.269 0.000
I08.9 Multiple valve disease, unspecified
0.730 0.270 0.000
V80-V89 Other land transport accidents
0.730 0.270 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.729 0.271 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.727 0.273 0.000
Y84.6 Urinary catheterisation
0.727 0.273 0.000
E16.2 Hypoglycaemia, unspecified
0.726 0.274 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.724 0.276 0.000
Q80-Q89 Other congenital malformations
0.723 0.277 0.000
X60-X84 Intentional self-harm
0.723 0.277 0.000
Z56 Problems related to employment and unemployment
0.722 0.278 0.000
Z92.8 Personal history of other medical treatment
0.722 0.278 0.000
D69.4 Other primary thrombocytopenia
0.722 0.278 0.000
Z57.3 Occupational exposure to other air contaminants
0.722 0.278 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.721 0.279 0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft
0.720 0.280 0.000
X20-X29 Contact with venomous animals and plants
0.720 0.280 0.000
S42 Fracture of shoulder and upper arm
0.718 0.282 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.718 0.282 0.000
Z85 Personal history of malignant neoplasm
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.717 0.283 0.000
Y10-Y34 Event of undetermined intent
0.717 0.283 0.000
X85-X99 Assault
0.717 0.283 0.000
X30-X39 Exposure to forces of nature
0.717 0.283 0.000
X00-X09 Exposure to smoke, fire and flames
0.717 0.283 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.717 0.283 0.000
W75-W84 Other accidental threats to breathing
0.717 0.283 0.000
W65-W74 Accidental drowning and submersion
0.717 0.283 0.000
V98-V99 Other and unspecified transport accidents
0.717 0.283 0.000
V95-V97 Air and space transport accidents
0.717 0.283 0.000
V90-V94 Water transport accidents
0.717 0.283 0.000
V70-V79 Bus occupant injured in transport accident
0.717 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.717 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.717 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.717 0.283 0.000
V01-V09 Pedestrian injured in transport accident
0.717 0.283 0.000
Z92.9 Personal history of medical treatment, unspecified
0.716 0.284 0.000
Z92.5 Personal history of rehabilitation measures
0.716 0.284 0.000
E26 Hyperaldosteronism
0.716 0.284 0.000
Z42.9 Follow-up care involving plastic surgery, unspecified
0.716 0.284 0.000
T33-T35 Frostbite
0.715 0.285 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.715 0.285 0.000
T00-T07 Injuries involving multiple body regions
0.715 0.285 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.714 0.286 0.000
E28 Ovarian dysfunction
0.714 0.286 0.000
E34 Other endocrine disorders
0.709 0.291 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.708 0.292 0.000
T78 Adverse effects, not elsewhere classified
0.708 0.292 0.000
E84 Cystic fibrosis
0.707 0.293 0.000
E79 Disorders of purine and pyrimidine metabolism
0.707 0.293 0.000
E77 Disorders of glycoprotein metabolism
0.707 0.293 0.000
E76 Disorders of glycosaminoglycan metabolism
0.707 0.293 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.707 0.293 0.000
E72 Other disorders of amino-acid metabolism
0.707 0.293 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.707 0.293 0.000
E70 Disorders of aromatic amino-acid metabolism
0.707 0.293 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.707 0.293 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.707 0.293 0.000
I00-I02 Acute rheumatic fever
0.706 0.294 0.000
T82.3 Mechanical complication of other vascular grafts
0.705 0.295 0.000
Z93.2 Ileostomy status
0.703 0.297 0.000
Z88.2 Personal history of allergy to sulphonamides
0.703 0.297 0.000
X10-X19 Contact with heat and hot substances
0.702 0.298 0.000
Y65 Other misadventures during surgical and medical care
0.701 0.299 0.000
D66 Hereditary factor VIII deficiency
0.701 0.299 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.700 0.300 0.000
B02 Zoster [herpes zoster]
0.700 0.300 0.000
S46.0 Injury of tendon of the rotator cuff of shoulder
0.700 0.300 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.699 0.301 0.000
E83.8 Other disorders of mineral metabolism
0.699 0.301 0.000
E83.2 Disorders of zinc metabolism
0.699 0.301 0.000
E83.0 Disorders of copper metabolism
0.699 0.301 0.000
Y59 Other and unspecified vaccines and biological substances
0.699 0.301 0.000
Y58 Bacterial vaccines
0.699 0.301 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.699 0.301 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.699 0.301 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.699 0.301 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.699 0.301 0.000
Z81 Family history of mental and behavioural disorders
0.699 0.301 0.000
I52 Other heart disorders in diseases classified elsewhere
0.698 0.302 0.000
I48 Atrial fibrillation and flutter
0.698 0.302 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.698 0.302 0.000
I41 Myocarditis in diseases classified elsewhere
0.698 0.302 0.000
I40 Acute myocarditis
0.698 0.302 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.698 0.302 0.000
I32 Pericarditis in diseases classified elsewhere
0.698 0.302 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.697 0.302 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.697 0.303 0.000
E89.0 Postprocedural hypothyroidism
0.696 0.304 0.000
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs
0.695 0.305 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.695 0.305 0.000
E32 Diseases of thymus
0.695 0.305 0.000
E31 Polyglandular dysfunction
0.695 0.305 0.000
E30 Disorders of puberty, not elsewhere classified
0.695 0.305 0.000
E25 Adrenogenital disorders
0.695 0.305 0.000
H73.8 Other specified disorders of tympanic membrane
0.694 0.306 0.000
I37 Pulmonary valve disorders
0.692 0.308 0.000
I31.0 Chronic adhesive pericarditis
0.691 0.308 0.000
E55 Vitamin D deficiency
0.692 0.308 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.690 0.310 0.000
S19 Other and unspecified injuries of neck
0.688 0.312 0.000
Y83.5 Amputation of limb(s)
0.687 0.313 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.687 0.313 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.687 0.313 0.000
T14 Injury of unspecified body region
0.686 0.314 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.686 0.314 0.000
U89 Agent resistant to other and unspecified antibiotics
0.686 0.314 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.685 0.315 0.000
Z94 Transplanted organ and tissue status
0.685 0.315 0.000
I23 Certain current complications following acute myocardial infarction
0.685 0.315 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.685 0.315 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.685 0.315 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.683 0.317 0.000
Z80.4 Family history of malignant neoplasm of genital organs
0.683 0.317 0.000
Y45.1 Salicylates
0.683 0.317 0.000
Z65 Problems related to other psychosocial circumstances
0.683 0.317 0.000
Z64 Problems related to certain psychosocial circumstances
0.683 0.317 0.000
Z62 Other problems related to upbringing
0.683 0.317 0.000
Z61 Problems related to negative life events in childhood
0.683 0.317 0.000
Z55 Problems related to education and literacy
0.683 0.317 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.683 0.317 0.000
I25.6 Silent myocardial ischaemia
0.683 0.317 0.000
T86 Failure and rejection of transplanted organs and tissues
0.682 0.318 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.681 0.319 0.000
S20-S29 Injuries to the thorax
0.680 0.320 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.679 0.321 0.000
Z42.8 Follow-up care involving plastic surgery of other body part
0.678 0.322 0.000
Z42.4 Follow-up care involving plastic surgery of lower extremity
0.678 0.322 0.000
D60-D64 Aplastic and other anaemias
0.678 0.322 0.000
S72.30 Fracture of shaft of femur (closed)
0.676 0.323 0.000
E04.0 Non-toxic diffuse goitre
0.675 0.325 0.000
I25.4 Coronary artery aneurysm
0.675 0.325 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.674 0.326 0.000
E00 Congenital iodine-deficiency syndrome
0.674 0.326 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.674 0.326 0.000
Y48 Anaesthetics and therapeutic gases
0.674 0.326 0.000
B02.9 Zoster without complication
0.674 0.326 0.000
I09 Other rheumatic heart diseases
0.672 0.328 0.000
E74 Other disorders of carbohydrate metabolism
0.671 0.328 0.000
Z57.2 Occupational exposure to dust
0.671 0.329 0.000
Z83.6 Family history of diseases of the respiratory system
0.671 0.329 0.000
Z83.2 Family history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.671 0.329 0.000
Z83.1 Family history of other infectious and parasitic diseases
0.671 0.329 0.000
Z83.0 Family history of human immunodeficiency virus [HIV]
0.671 0.329 0.000
Z43.2 Attention to ileostomy
0.670 0.330 0.000
U88 Agent resistant to multiple antibiotics
0.669 0.331 0.000
Y64 Contaminated medical or biological substances
0.669 0.331 0.000
Y63 Failure in dosage during surgical and medical care
0.669 0.331 0.000
Y62 Failure of sterile precautions during surgical and medical care
0.669 0.331 0.000
Y61 Foreign object accidentally left in body during surgical and medical care
0.669 0.331 0.000
Y69 Unspecified misadventure during surgical and medical care
0.669 0.331 0.000
Y66 Nonadministration of surgical and medical care
0.669 0.331 0.000
Y45.5 4-Aminophenol derivatives
0.669 0.331 0.000
Z80.6 Family history of leukaemia
0.669 0.331 0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics
0.667 0.333 0.000
Z42.3 Follow-up care involving plastic surgery of upper extremity
0.666 0.334 0.000
Z44.8 Fitting and adjustment of other external prosthetic devices
0.666 0.334 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.665 0.335 0.000
E06.9 Thyroiditis, unspecified
0.665 0.335 0.000
Y43.9 Primarily systemic agent, unspecified
0.665 0.335 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.665 0.335 0.000
Y43.6 Enzymes, not elsewhere classified
0.665 0.335 0.000
Y43.5 Acidifying and alkalising agents
0.665 0.335 0.000
Y43.2 Antineoplastic natural products
0.665 0.335 0.000
Y43.0 Antiallergic and antiemetic drugs
0.665 0.335 0.000
T83.2 Mechanical complication of graft of urinary organ
0.664 0.335 0.000
E27.9 Disorder of adrenal gland, unspecified
0.664 0.336 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.664 0.336 0.000
E27.5 Adrenomedullary hyperfunction
0.663 0.336 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.663 0.336 0.000
E27.0 Other adrenocortical overactivity
0.663 0.336 0.000
I06 Rheumatic aortic valve diseases
0.663 0.337 0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.662 0.338 0.000
H66.3 Other chronic suppurative otitis media
0.662 0.338 0.000
T20 Burn and corrosion of head and neck
0.662 0.338 0.000
E73 Lactose intolerance
0.661 0.338 0.000
E20 Hypoparathyroidism
0.661 0.339 0.000
E87.4 Mixed disorder of acid-base balance
0.661 0.339 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.661 0.339 0.000
I34.0 Mitral (valve) insufficiency
0.661 0.339 0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract
0.660 0.339 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.659 0.341 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.658 0.341 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.658 0.342 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.658 0.342 0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen
0.658 0.342 0.000
E85 Amyloidosis
0.657 0.343 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.657 0.343 0.000
D67 Hereditary factor IX deficiency
0.656 0.344 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.656 0.344 0.000
Y43.1 Antineoplastic antimetabolites
0.655 0.345 0.000
S78 Traumatic amputation of hip and thigh
0.653 0.346 0.000
S77 Crushing injury of hip and thigh
0.653 0.346 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.653 0.346 0.000
S75 Injury of blood vessels at hip and thigh level
0.653 0.346 0.000
S74 Injury of nerves at hip and thigh level
0.653 0.346 0.000
S14 Injury of nerves and spinal cord at neck level
0.653 0.347 0.000
Y83.4 Other reconstructive surgery
0.653 0.347 0.000
S70 Superficial injury of hip and thigh
0.652 0.348 0.000
I47 Paroxysmal tachycardia
0.652 0.348 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.652 0.348 0.000
T87 Complications peculiar to reattachment and amputation
0.651 0.349 0.000
S48 Traumatic amputation of shoulder and upper arm
0.650 0.349 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.650 0.349 0.000
S44 Injury of nerves at shoulder and upper arm level
0.650 0.349 0.000
S47 Crushing injury of shoulder and upper arm
0.650 0.349 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.650 0.350 0.000
Z93.9 Artificial opening status, unspecified
0.650 0.350 0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified
0.649 0.350 0.000
Y45.8 Other analgesics and antipyretics
0.649 0.350 0.000
Y45.4 Antirheumatics
0.649 0.350 0.000
D69.5 Secondary thrombocytopenia
0.649 0.351 0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
0.648 0.352 0.000
D69.8 Other specified haemorrhagic conditions
0.648 0.352 0.000
D69.2 Other nonthrombocytopenic purpura
0.648 0.352 0.000
D69.1 Qualitative platelet defects
0.648 0.352 0.000
D69.0 Allergic purpura
0.648 0.352 0.000
T82.1 Mechanical complication of cardiac electronic device
0.648 0.352 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.647 0.353 0.000
Z91.8 Personal history of other specified risk-factors, not elsewhere classified
0.647 0.353 0.000
Z91.7 Personal history of female genital mutilation
0.647 0.353 0.000
Z91.4 Personal history of psychological trauma, not elsewhere classified
0.647 0.353 0.000
Z91.3 Personal history of unhealthy sleep-wake schedule
0.647 0.353 0.000
Z91.2 Personal history of poor personal hygiene
0.647 0.353 0.000
X50-X57 Overexertion, travel and privation
0.646 0.353 0.000
Z54 Convalescence
0.646 0.354 0.000
H71 Cholesteatoma of middle ear
0.646 0.354 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.645 0.355 0.000
Y44 Agents primarily affecting blood constituents
0.645 0.355 0.000
H74.0 Tympanosclerosis
0.644 0.356 0.000
S72.4 Fracture of lower end of femur
0.644 0.356 0.000
E04.8 Other specified non-toxic goitre
0.644 0.356 0.000
A65-A69 Other spirochaetal diseases
0.644 0.356 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.643 0.357 0.000
I73 Other peripheral vascular diseases
0.643 0.357 0.000
E87.3 Alkalosis
0.642 0.357 0.000
T63 Toxic effect of contact with venomous animals
0.642 0.358 0.000
W06 Fall involving bed
0.642 0.358 0.000
I42 Cardiomyopathy
0.642 0.358 0.000
T80.9 Unspecified complication following infusion, transfusion and therapeutic injection
0.642 0.358 0.000
T80.6 Other serum reactions
0.642 0.358 0.000
T80.5 Anaphylactic shock due to serum
0.642 0.358 0.000
T80.4 Rh incompatibility reaction
0.642 0.358 0.000
T80.3 ABO incompatibility reaction
0.642 0.358 0.000
T80.1 Vascular complications following infusion, transfusion and therapeutic injection
0.642 0.358 0.000
T80.0 Air embolism following infusion, transfusion and therapeutic injection
0.642 0.358 0.000
I25.5 Ischaemic cardiomyopathy
0.642 0.358 0.000
Z57.9 Occupational exposure to unspecified risk-factor
0.641 0.358 0.000
Z57.8 Occupational exposure to other risk-factors
0.641 0.358 0.000
Z57.7 Occupational exposure to vibration
0.641 0.358 0.000
Z57.6 Occupational exposure to extreme temperature
0.641 0.358 0.000
Z57.4 Occupational exposure to toxic agents in agriculture
0.641 0.358 0.000
Z57.1 Occupational exposure to radiation
0.641 0.358 0.000
Z57.0 Occupational exposure to noise
0.641 0.358 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.641 0.359 0.000
Z48 Other surgical follow-up care
0.638 0.362 0.000
E89.2 Postprocedural hypoparathyroidism
0.638 0.362 0.000
Z58.5 Exposure to other pollution
0.637 0.362 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.637 0.363 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.637 0.363 0.000
V20-V29 Motorcycle rider injured in transport accident
0.636 0.363 0.000
Y45.2 Propionic acid derivatives
0.636 0.364 0.000
Z92.3 Personal history of irradiation
0.634 0.366 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.634 0.366 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.634 0.366 0.000
D69.9 Haemorrhagic condition, unspecified
0.633 0.366 0.000
S40.8 Other superficial injuries of shoulder and upper arm
0.633 0.367 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.633 0.367 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.633 0.367 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.631 0.368 0.000
E45 Retarded development following protein-energy malnutrition
0.631 0.368 0.000
E43 Unspecified severe protein-energy malnutrition
0.631 0.368 0.000
E42 Marasmic kwashiorkor
0.631 0.368 0.000
E41 Nutritional marasmus
0.631 0.368 0.000
E40 Kwashiorkor
0.631 0.368 0.000
Z52 Donors of organs and tissues
0.631 0.369 0.000
Z49.1 Extracorporeal dialysis
0.631 0.369 0.000
Y57 Other and unspecified drugs and medicaments
0.631 0.369 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.630 0.370 0.000
Y60.9 During unspecified surgical and medical care
0.630 0.370 0.000
Y60.8 During other surgical and medical care
0.630 0.370 0.000
Y60.7 During administration of enema
0.630 0.370 0.000
Y60.6 During aspiration, puncture and other catheterisation
0.630 0.370 0.000
Y60.5 During heart catheterisation
0.630 0.370 0.000
Y60.3 During injection or immunisation
0.630 0.370 0.000
Y60.2 During kidney dialysis or other perfusion
0.630 0.370 0.000
Y60.1 During infusion or transfusion
0.630 0.370 0.000
T78.4 Allergy, unspecified
0.630 0.370 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.630 0.370 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.630 0.370 0.000
T17 Foreign body in respiratory tract
0.629 0.371 0.000
E15 Nondiabetic hypoglycaemic coma
0.629 0.371 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.625 0.374 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.625 0.375 0.000
Q35-Q37 Cleft lip and cleft palate
0.625 0.375 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.625 0.375 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.625 0.375 0.000
S72.9 Fracture of femur, part unspecified
0.625 0.375 0.000
S72.8 Fractures of other parts of femur
0.625 0.375 0.000
S72.7 Multiple fractures of femur
0.625 0.375 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.625 0.375 0.000
V19 Pedal cyclist injured in other and unspecified transport accidents
0.623 0.377 0.000
Z63.8 Other specified problems related to primary support group
0.622 0.378 0.000
I31.8 Other specified diseases of pericardium
0.621 0.379 0.000
I31.2 Haemopericardium, not elsewhere classified
0.621 0.379 0.000
I31.1 Chronic constrictive pericarditis
0.621 0.379 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.621 0.379 0.000
Z40.9 Prophylactic surgery, unspecified
0.620 0.380 0.000
I71 Aortic aneurysm and dissection
0.620 0.380 0.000
Y42.9 Other and unspecified hormone antagonists
0.619 0.381 0.000
Y42.4 Oral contraceptives
0.619 0.381 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.619 0.381 0.000
Y42.2 Antithyroid drugs
0.619 0.381 0.000
Y42.1 Thyroid hormones and substitutes
0.619 0.381 0.000
E29 Testicular dysfunction
0.618 0.382 0.000
I73.0 Raynaud's syndrome
0.618 0.382 0.000
S41.1 Open wound of upper arm
0.618 0.382 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.618 0.382 0.000
S71 Open wound of hip and thigh
0.617 0.382 0.000
W60 Contact with plant thorns and spines and sharp leaves
0.616 0.384 0.000
Z46 Fitting and adjustment of other devices
0.616 0.384 0.000
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues
0.615 0.385 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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