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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs61907580
log Bayes Factor = 11.682
Chromosome 11   position 126,979,429  (GRCh37) Explore rs61907580 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
N17-N19 Renal failure
1.000 0.000 0.000
N17 Acute renal failure
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
0.999 0.001 0.000
N17.9 Acute renal failure, unspecified
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
N10-N16 Renal tubulo-interstitial diseases
0.998 0.002 0.000
N13 Obstructive and reflux uropathy
0.996 0.004 0.000
M20-M25 Other joint disorders
0.996 0.004 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.996 0.004 0.000
D10-D36 Benign neoplasms
0.995 0.005 0.000
D25 Leiomyoma of uterus
0.992 0.008 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.992 0.008 0.000
M25 Other joint disorders, not elsewhere classified
0.987 0.013 0.000
D25.9 Leiomyoma of uterus, unspecified
0.986 0.014 0.000
N18 Chronic renal failure
0.985 0.015 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.982 0.018 0.000
Chapter I Certain infectious and parasitic diseases
0.980 0.020 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.969 0.031 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.965 0.035 0.000
N13.3 Other and unspecified hydronephrosis
0.965 0.035 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.963 0.037 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.962 0.038 0.000
N18.9 Chronic renal failure, unspecified
0.956 0.044 0.000
D27 Benign neoplasm of ovary
0.949 0.051 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.943 0.057 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.943 0.057 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.943 0.057 0.000
A00-A09 Intestinal infectious diseases
0.940 0.060 0.000
M86-M90 Other osteopathies
0.938 0.062 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.934 0.066 0.000
O60-O75 Complications of labour and delivery
0.933 0.067 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.928 0.072 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.921 0.079 0.000
M25.5 Pain in joint
0.915 0.085 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.912 0.088 0.000
A30-A49 Other bacterial diseases
0.911 0.089 0.000
D18 Haemangioma and lymphangioma, any site
0.908 0.092 0.000
Chapter XXII Codes for special purposes
0.901 0.099 0.000
Y43 Primarily systemic agents
0.900 0.100 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.898 0.102 0.000
C83.3 Large cell (diffuse)
0.897 0.103 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.894 0.106 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.891 0.109 0.000
A04 Other bacterial intestinal infections
0.890 0.110 0.000
M22 Disorders of patella
0.889 0.111 0.000
M25.4 Effusion of joint
0.885 0.115 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.885 0.115 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.883 0.117 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.883 0.117 0.000
M24 Other specific joint derangements
0.878 0.122 0.000
D11 Benign neoplasm of major salivary glands
0.874 0.126 0.000
D25.2 Subserosal leiomyoma of uterus
0.871 0.129 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.870 0.130 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.866 0.134 0.000
E70-E90 Metabolic disorders
0.866 0.134 0.000
D25.0 Submucous leiomyoma of uterus
0.865 0.135 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.864 0.136 0.000
E86 Volume depletion
0.858 0.142 0.000
B35-B49 Mycoses
0.854 0.146 0.000
A08 Viral and other specified intestinal infections
0.854 0.146 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.852 0.148 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.852 0.148 0.000
C15-C26 Malignant neoplasms of digestive organs
0.851 0.149 0.000
M21 Other acquired deformities of limbs
0.849 0.151 0.000
Y52 Agents primarily affecting the cardiovascular system
0.849 0.151 0.000
N00-N08 Glomerular diseases
0.848 0.152 0.000
C01 Malignant neoplasm of base of tongue
0.847 0.153 0.000
D18.0 Haemangioma, any site
0.846 0.154 0.000
Chapter VIII Diseases of the ear and mastoid process
0.844 0.156 0.000
M87 Osteonecrosis
0.844 0.156 0.000
M25.8 Other specified joint disorders
0.844 0.156 0.000
N18.0 End-stage renal disease
0.844 0.156 0.000
C64-C68 Malignant neoplasms of urinary tract
0.843 0.157 0.000
M31 Other necrotising vasculopathies
0.841 0.159 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.841 0.159 0.000
N18.8 Other chronic renal failure
0.840 0.160 0.000
N18.5 Chronic kidney disease, stage 5
0.839 0.161 0.000
Y86 Sequelae of other accidents
0.839 0.161 0.000
T91 Sequelae of injuries of neck and trunk
0.838 0.162 0.000
M25.46 Effusion of joint (Lower leg)
0.836 0.164 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.836 0.164 0.000
T92 Sequelae of injuries of upper limb
0.835 0.165 0.000
Y42.5 Other oestrogens and progestogens
0.835 0.165 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.832 0.168 0.000
M25.7 Osteophyte
0.831 0.169 0.000
Y95 Nosocomial condition
0.829 0.171 0.000
A49 Bacterial infection of unspecified site
0.828 0.172 0.000
O69.2 Labour and delivery complicated by other cord entanglement
0.827 0.173 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.826 0.174 0.000
M91-M94 Chondropathies
0.825 0.175 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.824 0.176 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.824 0.176 0.000
D35.1 Parathyroid gland
0.823 0.177 0.000
M30 Polyarteritis nodosa and related conditions
0.822 0.178 0.000
T90 Sequelae of injuries of head
0.821 0.179 0.000
N10 Acute tubulo-interstitial nephritis
0.817 0.183 0.000
M40-M43 Deforming dorsopathies
0.816 0.184 0.000
A08.1 Acute gastro-enteropathy due to Norwalk agent
0.815 0.185 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.814 0.186 0.000
T66-T78 Other and unspecified effects of external causes
0.813 0.187 0.000
M88 Paget's disease of bone [osteitis deformans]
0.811 0.188 0.000
M25.51 Pain in joint (Shoulder region)
0.811 0.189 0.000
S40-S49 Injuries to the shoulder and upper arm
0.811 0.189 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.810 0.190 0.000
Y43.3 Other antineoplastic drugs
0.808 0.192 0.000
E00-E07 Disorders of thyroid gland
0.807 0.193 0.000
Y40 Systemic antibiotics
0.803 0.196 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.802 0.198 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.802 0.198 0.000
D36 Benign neoplasm of other and unspecified sites
0.801 0.199 0.000
Y48 Anaesthetics and therapeutic gases
0.800 0.200 0.000
A04.5 Campylobacter enteritis
0.799 0.201 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.798 0.202 0.000
V40-V49 Car occupant injured in transport accident
0.798 0.202 0.000
T98 Sequelae of other and unspecified effects of external causes
0.797 0.203 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.796 0.204 0.000
D41.4 Bladder
0.794 0.206 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.793 0.207 0.000
D32 Benign neoplasm of meninges
0.793 0.207 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.792 0.208 0.000
C02.9 Tongue, unspecified
0.792 0.208 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.791 0.209 0.000
N13.4 Hydroureter
0.790 0.210 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.790 0.210 0.000
W50-W64 Exposure to animate mechanical forces
0.789 0.211 0.000
D11.0 Parotid gland
0.787 0.213 0.000
B50-B64 Protozoal diseases
0.786 0.214 0.000
D37.4 Colon
0.784 0.216 0.000
N13.8 Other obstructive and reflux uropathy
0.784 0.216 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.784 0.216 0.000
M22.2 Patellofemoral disorders
0.783 0.217 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.782 0.218 0.000
M60-M63 Disorders of muscles
0.782 0.218 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.781 0.219 0.000
N11 Chronic tubulo-interstitial nephritis
0.780 0.220 0.000
O20 Haemorrhage in early pregnancy
0.779 0.221 0.000
M34 Systemic sclerosis
0.778 0.222 0.000
C06 Malignant neoplasm of other and unspecified parts of mouth
0.777 0.223 0.000
M87.9 Osteonecrosis, unspecified
0.776 0.224 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.776 0.224 0.000
M25.56 Pain in joint (Lower leg)
0.776 0.224 0.000
N30-N39 Other diseases of urinary system
0.776 0.224 0.000
Chapter VII Diseases of the eye and adnexa
0.775 0.225 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.774 0.226 0.000
Q50-Q56 Congenital malformations of genital organs
0.773 0.227 0.000
M50-M54 Other dorsopathies
0.772 0.228 0.000
U80 Agent resistant to penicillin and related antibiotics
0.769 0.231 0.000
M21.3 Wrist or foot drop (acquired)
0.769 0.231 0.000
M70-M79 Other soft tissue disorders
0.765 0.235 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.765 0.235 0.000
M45-M49 Spondylopathies
0.765 0.235 0.000
H65-H75 Diseases of middle ear and mastoid
0.764 0.236 0.000
T93 Sequelae of injuries of lower limb
0.764 0.236 0.000
X60-X84 Intentional self-harm
0.763 0.237 0.000
M25.3 Other instability of joint
0.763 0.237 0.000
T79-T79 Certain early complications of trauma
0.761 0.239 0.000
X50-X57 Overexertion, travel and privation
0.759 0.241 0.000
N13.6 Pyonephrosis
0.758 0.242 0.000
D37.7 Other digestive organs
0.758 0.242 0.000
C65 Malignant neoplasm of renal pelvis
0.757 0.242 0.000
E20-E35 Disorders of other endocrine glands
0.757 0.243 0.000
A04.7 Enterocolitis due to Clostridium difficile
0.756 0.243 0.000
E40-E46 Malnutrition
0.755 0.245 0.000
W20-W49 Exposure to inanimate mechanical forces
0.753 0.247 0.000
Y00-Y09 Assault
0.752 0.247 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.752 0.248 0.000
D14.1 Larynx
0.750 0.250 0.000
M22.4 Chondromalacia patellae
0.747 0.253 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.745 0.254 0.000
O61 Failed induction of labour
0.745 0.255 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.745 0.255 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.745 0.255 0.000
X10-X19 Contact with heat and hot substances
0.744 0.256 0.000
S90-S99 Injuries to the ankle and foot
0.743 0.257 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.741 0.259 0.000
O85-O92 Complications predominantly related to the puerperium
0.741 0.259 0.000
W00-W19 Falls
0.741 0.259 0.000
S32 Fracture of lumbar spine and pelvis
0.740 0.260 0.000
H53-H54 Visual disturbances and blindness
0.740 0.260 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.739 0.260 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.739 0.261 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.738 0.262 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.738 0.262 0.000
Y57 Other and unspecified drugs and medicaments
0.736 0.264 0.000
V10-V19 Pedal cyclist injured in transport accident
0.734 0.266 0.000
M25.76 Osteophyte (Lower leg)
0.734 0.266 0.000
O75.7 Vaginal delivery following previous Caesarean section
0.734 0.266 0.000
N30 Cystitis
0.734 0.266 0.000
S70-S79 Injuries to the hip and thigh
0.733 0.267 0.000
C21 Malignant neoplasm of anus and anal canal
0.733 0.267 0.000
T14 Injury of unspecified body region
0.732 0.268 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.731 0.269 0.000
M00-M03 Infectious arthropathies
0.731 0.269 0.000
C07 Malignant neoplasm of parotid gland
0.730 0.269 0.000
C04 Malignant neoplasm of floor of mouth
0.730 0.270 0.000
Y89 Sequelae of other external causes
0.729 0.271 0.000
T90.5 Sequelae of intracranial injury
0.729 0.271 0.000
Y43.4 Immunosuppressive agents
0.729 0.271 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.728 0.271 0.000
D41.2 Ureter
0.728 0.272 0.000
X20-X29 Contact with venomous animals and plants
0.728 0.272 0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)
0.728 0.272 0.000
M90 Osteopathies in diseases classified elsewhere
0.728 0.272 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.725 0.275 0.000
D37.5 Rectum
0.725 0.275 0.000
Y44 Agents primarily affecting blood constituents
0.724 0.275 0.000
Q80-Q89 Other congenital malformations
0.724 0.276 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.724 0.276 0.000
M80-M85 Disorders of bone density and structure
0.723 0.277 0.000
C88 Malignant immunoproliferative diseases
0.723 0.277 0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb
0.723 0.277 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.723 0.277 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.723 0.277 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.722 0.278 0.000
M88.9 Paget's disease of bone, unspecified
0.721 0.279 0.000
O75.0 Maternal distress during labour and delivery
0.720 0.280 0.000
B35 Dermatophytosis
0.719 0.281 0.000
N05 Unspecified nephritic syndrome
0.718 0.282 0.000
Q00-Q07 Congenital malformations of the nervous system
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.717 0.283 0.000
N17.8 Other acute renal failure
0.717 0.283 0.000
N17.2 Acute renal failure with medullary necrosis
0.717 0.283 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.717 0.283 0.000
N17.0 Acute renal failure with tubular necrosis
0.717 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.717 0.283 0.000
Y10-Y34 Event of undetermined intent
0.717 0.283 0.000
X85-X99 Assault
0.717 0.283 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.717 0.283 0.000
X30-X39 Exposure to forces of nature
0.717 0.283 0.000
X00-X09 Exposure to smoke, fire and flames
0.717 0.283 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.717 0.283 0.000
W75-W84 Other accidental threats to breathing
0.717 0.283 0.000
W65-W74 Accidental drowning and submersion
0.717 0.283 0.000
V98-V99 Other and unspecified transport accidents
0.717 0.283 0.000
V95-V97 Air and space transport accidents
0.717 0.283 0.000
V90-V94 Water transport accidents
0.717 0.283 0.000
V70-V79 Bus occupant injured in transport accident
0.717 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.717 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.717 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.717 0.283 0.000
V01-V09 Pedestrian injured in transport accident
0.717 0.283 0.000
D43.0 Brain, supratentorial
0.716 0.284 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.716 0.284 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.716 0.284 0.000
M25.50 Pain in joint (Multiple sites)
0.715 0.285 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.715 0.285 0.000
N15 Other renal tubulo-interstitial diseases
0.715 0.285 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.715 0.285 0.000
A41 Other septicaemia
0.714 0.286 0.000
H65 Nonsuppurative otitis media
0.714 0.286 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.714 0.286 0.000
T78 Adverse effects, not elsewhere classified
0.714 0.286 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.714 0.286 0.000
M33 Dermatopolymyositis
0.714 0.286 0.000
M32 Systemic lupus erythematosus
0.714 0.286 0.000
Y59 Other and unspecified vaccines and biological substances
0.714 0.286 0.000
Y58 Bacterial vaccines
0.714 0.286 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.714 0.286 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.714 0.286 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.714 0.286 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.714 0.286 0.000
M25.9 Joint disorder, unspecified
0.714 0.286 0.000
D31 Benign neoplasm of eye and adnexa
0.713 0.287 0.000
D29 Benign neoplasm of male genital organs
0.713 0.287 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.713 0.287 0.000
D19 Benign neoplasm of mesothelial tissue
0.713 0.287 0.000
D16 Benign neoplasm of bone and articular cartilage
0.713 0.287 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.713 0.287 0.000
H53 Visual disturbances
0.713 0.287 0.000
T33-T35 Frostbite
0.711 0.289 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.711 0.289 0.000
T00-T07 Injuries involving multiple body regions
0.711 0.289 0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)
0.711 0.289 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.711 0.289 0.000
T91.3 Sequelae of injury of spinal cord
0.711 0.289 0.000
D36.7 Other specified sites
0.710 0.290 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.710 0.290 0.000
N25-N29 Other disorders of kidney and ureter
0.710 0.290 0.000
A48 Other bacterial diseases, not elsewhere classified
0.710 0.290 0.000
O72 Postpartum haemorrhage
0.709 0.291 0.000
M25.2 Flail joint
0.707 0.292 0.000
M25.1 Fistula of joint
0.707 0.292 0.000
M25.0 Haemarthrosis
0.707 0.292 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.706 0.293 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.706 0.294 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.706 0.294 0.000
N18.1 Chronic kidney disease, stage 1
0.706 0.294 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.706 0.294 0.000
D48.1 Connective and other soft tissue
0.705 0.295 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.704 0.295 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.704 0.295 0.000
C10 Malignant neoplasm of oropharynx
0.704 0.296 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.703 0.297 0.000
B99-B99 Other infectious diseases
0.702 0.297 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.702 0.297 0.000
B65-B83 Helminthiases
0.702 0.297 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.702 0.297 0.000
A75-A79 Rickettsioses
0.702 0.297 0.000
A70-A74 Other diseases caused by chlamydiae
0.702 0.297 0.000
A65-A69 Other spirochaetal diseases
0.702 0.297 0.000
A20-A28 Certain zoonotic bacterial diseases
0.702 0.297 0.000
A15-A19 Tuberculosis
0.702 0.297 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.702 0.298 0.000
A04.8 Other specified bacterial intestinal infections
0.702 0.298 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.702 0.298 0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics
0.702 0.298 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.701 0.299 0.000
M25.52 Pain in joint (Upper arm)
0.701 0.299 0.000
O69.1 Labour and delivery complicated by cord around neck, with compression
0.700 0.300 0.000
N30.2 Other chronic cystitis
0.700 0.300 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.700 0.300 0.000
A49.0 Staphylococcal infection, unspecified
0.699 0.301 0.000
C85.1 B-cell lymphoma, unspecified
0.697 0.302 0.000
U80.8 Agent resistant to other penicillin-related antibiotic
0.696 0.304 0.000
N03 Chronic nephritic syndrome
0.696 0.304 0.000
D37.6 Liver, gallbladder and bile ducts
0.696 0.304 0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes
0.696 0.304 0.000
D30 Benign neoplasm of urinary organs
0.696 0.304 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.696 0.304 0.000
T95 Sequelae of burns, corrosions and frostbite
0.695 0.305 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.695 0.305 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.695 0.305 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.695 0.305 0.000
M24.0 Loose body in joint
0.693 0.307 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.693 0.307 0.000
S00-S09 Injuries to the head
0.693 0.307 0.000
D33.2 Brain, unspecified
0.692 0.308 0.000
A80-A89 Viral infections of the central nervous system
0.692 0.308 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.692 0.308 0.000
C13 Malignant neoplasm of hypopharynx
0.692 0.308 0.000
C11 Malignant neoplasm of nasopharynx
0.692 0.308 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.692 0.308 0.000
C05 Malignant neoplasm of palate
0.692 0.308 0.000
C03 Malignant neoplasm of gum
0.692 0.308 0.000
C00 Malignant neoplasm of lip
0.692 0.308 0.000
C12 Malignant neoplasm of pyriform sinus
0.692 0.308 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.691 0.308 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.691 0.309 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.691 0.309 0.000
C95 Leukaemia of unspecified cell type
0.691 0.309 0.000
C94 Other leukaemias of specified cell type
0.691 0.309 0.000
C93 Monocytic leukaemia
0.691 0.309 0.000
C86 Other specified types of T/NK-cell lymphoma
0.691 0.309 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.689 0.311 0.000
M45 Ankylosing spondylitis
0.688 0.312 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.687 0.313 0.000
D32.0 Cerebral meninges
0.687 0.313 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.686 0.314 0.000
H60-H62 Diseases of external ear
0.686 0.314 0.000
O62 Abnormalities of forces of labour
0.684 0.316 0.000
B36 Other superficial mycoses
0.684 0.316 0.000
O20.9 Haemorrhage in early pregnancy, unspecified
0.683 0.317 0.000
C51-C58 Malignant neoplasms of female genital organs
0.683 0.317 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.682 0.318 0.000
M77 Other enthesopathies
0.682 0.318 0.000
S41 Open wound of shoulder and upper arm
0.680 0.320 0.000
M25.81 Other specified joint disorders (Shoulder region)
0.680 0.320 0.000
M24.2 Disorder of ligament
0.680 0.320 0.000
E04 Other non-toxic goitre
0.679 0.321 0.000
M25.72 Osteophyte (Upper arm)
0.679 0.321 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.678 0.322 0.000
D46 Myelodysplastic syndromes
0.678 0.322 0.000
U80.1 Methicillin resistant agent
0.677 0.323 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.677 0.323 0.000
C20 Malignant neoplasm of rectum
0.677 0.323 0.000
O66 Other obstructed labour
0.676 0.324 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.676 0.324 0.000
Q35-Q37 Cleft lip and cleft palate
0.676 0.324 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.676 0.324 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.676 0.324 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.676 0.324 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.676 0.324 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.676 0.324 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.676 0.324 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.676 0.324 0.000
T36 Poisoning by systemic antibiotics
0.676 0.324 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.675 0.325 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.675 0.325 0.000
H53.9 Visual disturbance, unspecified
0.674 0.326 0.000
M25.87 Other specified joint disorders (Ankle and foot)
0.674 0.326 0.000
O71 Other obstetric trauma
0.674 0.326 0.000
A07 Other protozoal intestinal diseases
0.674 0.326 0.000
A06 Amoebiasis
0.674 0.326 0.000
A05 Other bacterial foodborne intoxications
0.674 0.326 0.000
A03 Shigellosis
0.674 0.326 0.000
A02 Other Salmonella infections
0.674 0.326 0.000
A01 Typhoid and paratyphoid fevers
0.674 0.326 0.000
A00 Cholera
0.674 0.326 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.674 0.326 0.000
T98.1 Sequelae of other and unspecified effects of external causes
0.674 0.326 0.000
D00-D09 In situ neoplasms
0.673 0.327 0.000
C83.0 Small cell (diffuse)
0.672 0.327 0.000
T42.4 Benzodiazepines
0.672 0.328 0.000
C83.7 Burkitt's tumour
0.670 0.330 0.000
C83.6 Undifferentiated (diffuse)
0.670 0.330 0.000
C83.5 Lymphoblastic (diffuse)
0.670 0.330 0.000
C83.4 Immunoblastic (diffuse)
0.670 0.330 0.000
C83.2 Mixed small and large cell (diffuse)
0.670 0.330 0.000
C83.1 Small cleaved cell (diffuse)
0.670 0.330 0.000
M25.53 Pain in joint (Forearm)
0.670 0.330 0.000
C91 Lymphoid leukaemia
0.669 0.331 0.000
O74 Complications of anaesthesia during labour and delivery
0.669 0.331 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.669 0.331 0.000
O60 Preterm delivery
0.669 0.331 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.669 0.331 0.000
M43 Other deforming dorsopathies
0.669 0.331 0.000
M89 Other disorders of bone
0.669 0.331 0.000
S80-S89 Injuries to the knee and lower leg
0.668 0.332 0.000
C71 Malignant neoplasm of brain
0.668 0.332 0.000
Y42.9 Other and unspecified hormone antagonists
0.665 0.335 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.665 0.335 0.000
Y42.4 Oral contraceptives
0.665 0.335 0.000
Y42.2 Antithyroid drugs
0.665 0.335 0.000
Y42.1 Thyroid hormones and substitutes
0.665 0.335 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.665 0.335 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.665 0.335 0.000
H53.0 Amblyopia ex anopsia
0.664 0.336 0.000
T40.2 Other opioids
0.664 0.336 0.000
M30.0 Polyarteritis nodosa
0.664 0.336 0.000
C17 Malignant neoplasm of small intestine
0.664 0.336 0.000
M24.1 Other articular cartilage disorders
0.663 0.337 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.663 0.337 0.000
O20.0 Threatened abortion
0.663 0.337 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.663 0.337 0.000
M25.45 Effusion of joint (Pelvic region and thigh)
0.662 0.337 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.662 0.338 0.000
Y40.9 Systemic antibiotic, unspecified
0.661 0.339 0.000
Y48.2 Other and unspecified general anaesthetics
0.661 0.339 0.000
O69.8 Labour and delivery complicated by other cord complications
0.659 0.341 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.659 0.341 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.659 0.341 0.000
A49.8 Other bacterial infections of unspecified site
0.658 0.342 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.658 0.342 0.000
Y52.1 Calcium-channel blockers
0.658 0.342 0.000
M94 Other disorders of cartilage
0.657 0.343 0.000
M25.58 Pain in joint (Other)
0.656 0.344 0.000
M88.90 Paget's disease of bone, unspecified (Multiple sites)
0.656 0.344 0.000
C02.1 Border of tongue
0.655 0.344 0.000
M31.6 Other giant cell arteritis
0.655 0.344 0.000
D37.9 Digestive organ, unspecified
0.654 0.346 0.000
D37.3 Appendix
0.654 0.346 0.000
D37.2 Small intestine
0.654 0.346 0.000
A44 Bartonellosis
0.653 0.347 0.000
A43 Nocardiosis
0.653 0.347 0.000
A42 Actinomycosis
0.653 0.347 0.000
A40 Streptococcal septicaemia
0.653 0.347 0.000
A39 Meningococcal infection
0.653 0.347 0.000
A37 Whooping cough
0.653 0.347 0.000
A36 Diphtheria
0.653 0.347 0.000
A32 Listeriosis
0.653 0.347 0.000
A31 Infection due to other mycobacteria
0.653 0.347 0.000
A30 Leprosy [Hansen's disease]
0.653 0.347 0.000
A46 Erysipelas
0.653 0.347 0.000
A38 Scarlet fever
0.653 0.347 0.000
A35 Other tetanus
0.653 0.347 0.000
A34 Obstetrical tetanus
0.653 0.347 0.000
A33 Tetanus neonatorum
0.653 0.347 0.000
S32.4 Fracture of acetabulum
0.653 0.347 0.000
B49 Unspecified mycosis
0.651 0.348 0.000
D18.1 Lymphangioma, any site
0.651 0.349 0.000
H65.2 Chronic serous otitis media
0.651 0.349 0.000
O24 Diabetes mellitus in pregnancy
0.651 0.349 0.000
T11 Other injuries of upper limb, level unspecified
0.650 0.350 0.000
M54 Dorsalgia
0.650 0.350 0.000
Y40.8 Other systemic antibiotics
0.649 0.351 0.000
Y46.4 Iminostilbenes
0.648 0.352 0.000
V80-V89 Other land transport accidents
0.648 0.352 0.000
T91.8 Sequelae of other specified injuries of neck and trunk
0.647 0.353 0.000
B59 Pneumocystosis
0.647 0.353 0.000
V20-V29 Motorcycle rider injured in transport accident
0.646 0.353 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.646 0.353 0.000
O75.8 Other specified complications of labour and delivery
0.646 0.354 0.000
D37.1 Stomach
0.646 0.354 0.000
Y43.9 Primarily systemic agent, unspecified
0.645 0.355 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.645 0.355 0.000
Y43.6 Enzymes, not elsewhere classified
0.645 0.355 0.000
Y43.5 Acidifying and alkalising agents
0.645 0.355 0.000
Y43.2 Antineoplastic natural products
0.645 0.355 0.000
Y43.0 Antiallergic and antiemetic drugs
0.645 0.355 0.000
A49.1 Streptococcal infection, unspecified
0.645 0.355 0.000
N99-N99 Other disorders of the genitourinary system
0.645 0.355 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.644 0.356 0.000
Y98 Lifestyle-related condition
0.644 0.356 0.000
Y97 Environmental-pollution-related condition
0.644 0.356 0.000
Y96 Work-related condition
0.644 0.356 0.000
T78.3 Angioneurotic oedema
0.644 0.356 0.000
D10 Benign neoplasm of mouth and pharynx
0.644 0.356 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.643 0.357 0.000
S05 Injury of eye and orbit
0.643 0.357 0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.643 0.357 0.000
D48.0 Bone and articular cartilage
0.643 0.357 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.642 0.358 0.000
T14.1 Open wound of unspecified body region
0.642 0.358 0.000
D35.2 Pituitary gland
0.642 0.358 0.000
C06.2 Retromolar area
0.642 0.358 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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