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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17028048
log Bayes Factor = 11.7118
Chromosome 1   position 112,129,736  (GRCh37) Explore rs17028048 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
M70-M79 Other soft tissue disorders
0.999 0.001 0.000
G30-G32 Other degenerative diseases of the nervous system
0.994 0.006 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.992 0.008 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.990 0.010 0.000
W00-W19 Falls
0.987 0.013 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.986 0.014 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.983 0.017 0.000
M50-M54 Other dorsopathies
0.982 0.018 0.000
S20-S29 Injuries to the thorax
0.981 0.019 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.980 0.020 0.000
F30-F39 Mood [affective] disorders
0.977 0.023 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.975 0.025 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.972 0.028 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.965 0.035 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.964 0.036 0.000
M79.0 Rheumatism, unspecified
0.961 0.039 0.000
M54 Dorsalgia
0.955 0.045 0.000
M40-M43 Deforming dorsopathies
0.954 0.046 0.000
S00-S09 Injuries to the head
0.953 0.047 0.000
G30 Alzheimer's disease
0.953 0.047 0.000
W19 Unspecified fall
0.951 0.049 0.000
F00 Dementia in Alzheimer's disease
0.948 0.052 0.000
M45-M49 Spondylopathies
0.947 0.053 0.000
G35 Multiple sclerosis
0.942 0.058 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.938 0.062 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.938 0.062 0.000
M54.9 Dorsalgia, unspecified
0.931 0.069 0.000
S06 Intracranial injury
0.928 0.072 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.928 0.072 0.000
G62 Other polyneuropathies
0.928 0.072 0.000
G70-G73 Diseases of myoneural junction and muscle
0.927 0.073 0.000
W20-W49 Exposure to inanimate mechanical forces
0.926 0.074 0.000
G37 Other demyelinating diseases of central nervous system
0.923 0.077 0.000
F60-F69 Disorders of adult personality and behaviour
0.923 0.077 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.919 0.081 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.918 0.082 0.000
F00.9 Dementia in Alzheimer's disease, unspecified
0.917 0.083 0.000
M79.6 Pain in limb
0.914 0.086 0.000
M80-M85 Disorders of bone density and structure
0.912 0.088 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.912 0.088 0.000
S70-S79 Injuries to the hip and thigh
0.911 0.089 0.000
G30.9 Alzheimer's disease, unspecified
0.911 0.089 0.000
G62.9 Polyneuropathy, unspecified
0.911 0.089 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.910 0.090 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.909 0.091 0.000
W19.2 School, other institution and public administrative area
0.908 0.092 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.907 0.093 0.000
S27 Injury of other and unspecified intrathoracic organs
0.906 0.094 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.906 0.094 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.904 0.096 0.000
M86-M90 Other osteopathies
0.903 0.097 0.000
M79.00 Rheumatism, unspecified (Multiple sites)
0.903 0.097 0.000
G71 Primary disorders of muscles
0.895 0.105 0.000
F03 Unspecified dementia
0.893 0.107 0.000
S10-S19 Injuries to the neck
0.893 0.107 0.000
M77 Other enthesopathies
0.893 0.107 0.000
M70.6 Trochanteric bursitis
0.892 0.108 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.890 0.110 0.000
T14 Injury of unspecified body region
0.889 0.111 0.000
M47 Spondylosis
0.888 0.112 0.000
F02 Dementia in other diseases classified elsewhere
0.887 0.113 0.000
S06.5 Traumatic subdural haemorrhage
0.886 0.114 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.886 0.114 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.879 0.121 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.867 0.133 0.000
F33 Recurrent depressive disorder
0.864 0.136 0.000
M47.9 Spondylosis, unspecified
0.862 0.138 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.860 0.140 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.860 0.140 0.000
M70.65 Trochanteric bursitis-Pelvic/Thigh
0.860 0.140 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.859 0.141 0.000
S22.4 Multiple fractures of ribs
0.857 0.143 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.857 0.143 0.000
M79.7 Fibromyalgia
0.857 0.143 0.000
S90-S99 Injuries to the ankle and foot
0.856 0.144 0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)
0.856 0.144 0.000
F99-F99 Unspecified mental disorder
0.856 0.144 0.000
M41 Scoliosis
0.855 0.145 0.000
G31.8 Other specified degenerative diseases of nervous system
0.853 0.147 0.000
W06 Fall involving bed
0.852 0.148 0.000
F60 Specific personality disorders
0.852 0.148 0.000
T14.0 Superficial injury of unspecified body region
0.850 0.150 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.849 0.151 0.000
M43 Other deforming dorsopathies
0.846 0.154 0.000
M77.4 Metatarsalgia
0.846 0.154 0.000
W22 Striking against or struck by other objects
0.845 0.155 0.000
F31 Bipolar affective disorder
0.844 0.156 0.000
S00 Superficial injury of head
0.843 0.157 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.841 0.159 0.000
F23 Acute and transient psychotic disorders
0.836 0.164 0.000
M54.1 Radiculopathy
0.836 0.164 0.000
M79.64 Pain in limb (Hand)
0.834 0.166 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.831 0.169 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.828 0.172 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.828 0.172 0.000
Y45.1 Salicylates
0.826 0.174 0.000
G71.1 Myotonic disorders
0.823 0.177 0.000
S22.40 Multiple fractures of ribs (closed)
0.822 0.178 0.000
V20-V29 Motorcycle rider injured in transport accident
0.821 0.178 0.000
S20 Superficial injury of thorax
0.821 0.179 0.000
M84 Disorders of continuity of bone
0.821 0.179 0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft
0.820 0.180 0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract
0.819 0.181 0.000
F32 Depressive episode
0.819 0.181 0.000
M20-M25 Other joint disorders
0.818 0.182 0.000
F25 Schizoaffective disorders
0.815 0.185 0.000
S72 Fracture of femur
0.813 0.186 0.000
M77.47 Metatarsalgia-Ankle/Foot
0.813 0.187 0.000
Y45.0 Opioids and related analgesics
0.812 0.188 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.811 0.188 0.000
M46 Other inflammatory spondylopathies
0.808 0.192 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.806 0.194 0.000
M25.51 Pain in joint (Shoulder region)
0.806 0.194 0.000
M53 Other dorsopathies, not elsewhere classified
0.804 0.196 0.000
M25 Other joint disorders, not elsewhere classified
0.803 0.197 0.000
M25.5 Pain in joint
0.803 0.197 0.000
Y48 Anaesthetics and therapeutic gases
0.802 0.198 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.800 0.200 0.000
W14 Fall from tree
0.799 0.201 0.000
G20-G26 Extrapyramidal and movement disorders
0.797 0.202 0.000
W17 Other fall from one level to another
0.797 0.203 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.796 0.204 0.000
G71.0 Muscular dystrophy
0.794 0.206 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.793 0.207 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.792 0.208 0.000
M79.67 Pain in limb (Ankle and foot)
0.789 0.211 0.000
Y86 Sequelae of other accidents
0.788 0.212 0.000
S27.0 Traumatic pneumothorax
0.787 0.213 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.787 0.213 0.000
S06.3 Focal brain injury
0.784 0.216 0.000
M79.63 Pain in limb (Forearm)
0.783 0.217 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.781 0.218 0.000
F01 Vascular dementia
0.780 0.220 0.000
W44 Foreign body entering into or through eye or natural orifice
0.780 0.220 0.000
M50 Cervical disk disorders
0.779 0.221 0.000
S72.0 Fracture of neck of femur
0.778 0.221 0.000
W45 Foreign body or object entering through skin
0.778 0.222 0.000
G90-G99 Other disorders of the nervous system
0.778 0.222 0.000
T79-T79 Certain early complications of trauma
0.776 0.224 0.000
T39.1 4-Aminophenol derivatives
0.776 0.224 0.000
X60-X84 Intentional self-harm
0.774 0.226 0.000
M25.56 Pain in joint (Lower leg)
0.773 0.227 0.000
W19.4 Street and highway
0.773 0.227 0.000
V10-V19 Pedal cyclist injured in transport accident
0.768 0.232 0.000
F30 Manic episode
0.768 0.232 0.000
M90 Osteopathies in diseases classified elsewhere
0.768 0.232 0.000
S27.1 Traumatic haemothorax
0.767 0.233 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.766 0.234 0.000
M79.9 Soft tissue disorder, unspecified
0.765 0.235 0.000
W22.9 Unspecified place
0.765 0.235 0.000
G30.0 Alzheimer's disease with early onset
0.763 0.237 0.000
M79.60 Pain in limb (Multiple sites)
0.763 0.237 0.000
X50-X57 Overexertion, travel and privation
0.762 0.238 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.762 0.238 0.000
F02.8 Dementia in other specified diseases classified elsewhere
0.762 0.238 0.000
M79.70 Fibromyalgia (Multiple sites)
0.761 0.239 0.000
G63.2 Diabetic polyneuropathy
0.759 0.241 0.000
M80 Osteoporosis with pathological fracture
0.757 0.243 0.000
W19.9 Unspecified place
0.757 0.243 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.757 0.243 0.000
W06.0 Home
0.756 0.244 0.000
M00-M03 Infectious arthropathies
0.754 0.246 0.000
S72.00 Fracture of neck of femur (closed)
0.754 0.246 0.000
F99 Mental disorder, not otherwise specified
0.753 0.247 0.000
F39 Unspecified mood [affective] disorder
0.752 0.248 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.752 0.248 0.000
Y45.8 Other analgesics and antipyretics
0.750 0.250 0.000
M47.2 Other spondylosis with radiculopathy
0.750 0.250 0.000
S00.1 Contusion of eyelid and periocular area
0.750 0.250 0.000
M34 Systemic sclerosis
0.749 0.251 0.000
M79.08 Rheumatism, unspecified (Other)
0.748 0.252 0.000
T11 Other injuries of upper limb, level unspecified
0.747 0.253 0.000
M54.19 Radiculopathy (Site unspecified)
0.747 0.253 0.000
S40-S49 Injuries to the shoulder and upper arm
0.747 0.253 0.000
W11 Fall on and from ladder
0.746 0.254 0.000
T00-T07 Injuries involving multiple body regions
0.746 0.254 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.746 0.254 0.000
T66-T78 Other and unspecified effects of external causes
0.745 0.255 0.000
M41.9 Scoliosis, unspecified
0.745 0.255 0.000
S12 Fracture of neck
0.744 0.256 0.000
M79.1 Myalgia
0.744 0.256 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.743 0.257 0.000
G31.0 Circumscribed brain atrophy
0.743 0.257 0.000
T39.0 Salicylates
0.743 0.257 0.000
T87 Complications peculiar to reattachment and amputation
0.741 0.258 0.000
S27.3 Other injuries of lung
0.740 0.260 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.740 0.260 0.000
S21 Open wound of thorax
0.737 0.263 0.000
F33.0 Recurrent depressive disorder, current episode mild
0.736 0.264 0.000
F23.9 Acute and transient psychotic disorder, unspecified
0.736 0.264 0.000
W08 Fall involving other furniture
0.735 0.265 0.000
W18 Other fall on same level
0.735 0.265 0.000
F34 Persistent mood [affective] disorders
0.735 0.265 0.000
F69 Unspecified disorder of adult personality and behaviour
0.734 0.266 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.734 0.266 0.000
G60 Hereditary and idiopathic neuropathy
0.734 0.266 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.733 0.267 0.000
W13 Fall from, out of or through building or structure
0.733 0.267 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.733 0.267 0.000
S06.2 Diffuse brain injury
0.732 0.268 0.000
F60.8 Other specific personality disorders
0.729 0.271 0.000
M54.2 Cervicalgia
0.729 0.271 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.729 0.271 0.000
S02 Fracture of skull and facial bones
0.729 0.271 0.000
W28 Contact with powered lawn mower
0.728 0.271 0.000
M82 Osteoporosis in diseases classified elsewhere
0.728 0.272 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.727 0.272 0.000
E20-E35 Disorders of other endocrine glands
0.727 0.273 0.000
M40 Kyphosis and lordosis
0.727 0.273 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.726 0.274 0.000
F60.3 Emotionally unstable personality disorder
0.725 0.275 0.000
M71 Other bursopathies
0.724 0.276 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.724 0.276 0.000
Y45.2 Propionic acid derivatives
0.724 0.276 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.723 0.277 0.000
W05 Fall involving wheelchair
0.723 0.277 0.000
M43.1 Spondylolisthesis
0.723 0.277 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.719 0.281 0.000
M54.8 Other dorsalgia
0.719 0.281 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.717 0.283 0.000
F70-F79 Mental retardation
0.717 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.717 0.283 0.000
Y10-Y34 Event of undetermined intent
0.717 0.283 0.000
X85-X99 Assault
0.717 0.283 0.000
X30-X39 Exposure to forces of nature
0.717 0.283 0.000
X00-X09 Exposure to smoke, fire and flames
0.717 0.283 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.717 0.283 0.000
W75-W84 Other accidental threats to breathing
0.717 0.283 0.000
W65-W74 Accidental drowning and submersion
0.717 0.283 0.000
V98-V99 Other and unspecified transport accidents
0.717 0.283 0.000
V95-V97 Air and space transport accidents
0.717 0.283 0.000
V90-V94 Water transport accidents
0.717 0.283 0.000
V70-V79 Bus occupant injured in transport accident
0.717 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.717 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.717 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.717 0.283 0.000
V01-V09 Pedestrian injured in transport accident
0.717 0.283 0.000
G61 Inflammatory polyneuropathy
0.717 0.283 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.716 0.284 0.000
Y00-Y09 Assault
0.716 0.284 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.716 0.284 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.714 0.286 0.000
S19 Other and unspecified injuries of neck
0.713 0.287 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.713 0.287 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.712 0.288 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.712 0.288 0.000
M79.3 Panniculitis, unspecified
0.711 0.289 0.000
M76 Enthesopathies of lower limb, excluding foot
0.711 0.289 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.710 0.290 0.000
F09 Unspecified organic or symptomatic mental disorder
0.710 0.290 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.710 0.290 0.000
S90 Superficial injury of ankle and foot
0.710 0.290 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.709 0.291 0.000
M79.2 Neuralgia and neuritis, unspecified
0.709 0.291 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.708 0.292 0.000
W15 Fall from cliff
0.708 0.292 0.000
W12 Fall on and from scaffolding
0.708 0.292 0.000
W09 Fall involving playground equipment
0.708 0.292 0.000
W04 Fall while being carried or supported by other persons
0.708 0.292 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.708 0.292 0.000
W00 Fall on same level involving ice and snow
0.708 0.292 0.000
T25 Burn and corrosion of ankle and foot
0.707 0.293 0.000
G36 Other acute disseminated demyelination
0.707 0.293 0.000
M89 Other disorders of bone
0.706 0.294 0.000
M87 Osteonecrosis
0.706 0.294 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.705 0.295 0.000
M85 Other disorders of bone density and structure
0.704 0.296 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.704 0.296 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.703 0.297 0.000
S26 Injury of heart
0.703 0.297 0.000
S25 Injury of blood vessels of thorax
0.703 0.297 0.000
S24 Injury of nerves and spinal cord at thorax level
0.703 0.297 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.703 0.297 0.000
S06.0 Concussion
0.703 0.297 0.000
Y59 Other and unspecified vaccines and biological substances
0.703 0.297 0.000
Y58 Bacterial vaccines
0.703 0.297 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.703 0.297 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.703 0.297 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.702 0.298 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.702 0.298 0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)
0.702 0.298 0.000
V40-V49 Car occupant injured in transport accident
0.702 0.298 0.000
F20 Schizophrenia
0.702 0.298 0.000
M60-M63 Disorders of muscles
0.702 0.298 0.000
W29 Contact with other powered hand tools and household machinery
0.702 0.298 0.000
E22 Hyperfunction of pituitary gland
0.701 0.299 0.000
M41.8 Other forms of scoliosis
0.700 0.299 0.000
F38 Other mood [affective] disorders
0.700 0.300 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.700 0.300 0.000
S22.2 Fracture of sternum
0.700 0.300 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.700 0.300 0.000
M54.3 Sciatica
0.700 0.300 0.000
G64 Other disorders of peripheral nervous system
0.699 0.301 0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)
0.699 0.301 0.000
F02.3 Dementia in Parkinson's disease
0.699 0.301 0.000
Y40 Systemic antibiotics
0.698 0.302 0.000
M50.2 Other cervical disk displacement
0.698 0.302 0.000
M79.62 Pain in limb (Upper arm)
0.697 0.303 0.000
T83.2 Mechanical complication of graft of urinary organ
0.697 0.303 0.000
F80-F89 Disorders of psychological development
0.696 0.303 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.694 0.306 0.000
S00.0 Superficial injury of scalp
0.694 0.306 0.000
Q80-Q89 Other congenital malformations
0.694 0.306 0.000
Y49.0 Tricyclic and tetracyclic antidepressants
0.693 0.307 0.000
E10-E14 Diabetes mellitus
0.693 0.307 0.000
M25.57 Pain in joint (Ankle and foot)
0.692 0.308 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.692 0.308 0.000
F25.9 Schizoaffective disorder, unspecified
0.692 0.308 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.692 0.308 0.000
X20-X29 Contact with venomous animals and plants
0.692 0.308 0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified
0.692 0.308 0.000
Y45.5 4-Aminophenol derivatives
0.692 0.308 0.000
Y45.4 Antirheumatics
0.692 0.308 0.000
M79.61 Pain in limb (Shoulder region)
0.692 0.308 0.000
M79.8 Other specified soft tissue disorders
0.691 0.308 0.000
G31.1 Senile degeneration of brain, not elsewhere classified
0.691 0.309 0.000
W19.1 Residential institution
0.691 0.309 0.000
M51 Other intervertebral disk disorders
0.691 0.309 0.000
F02.0 Dementia in Pick's disease
0.690 0.310 0.000
S20.2 Contusion of thorax
0.690 0.310 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.690 0.310 0.000
G71.3 Mitochondrial myopathy, not elsewhere classified
0.690 0.310 0.000
M79.07 Rheumatism, unspecified (Ankle and foot)
0.689 0.311 0.000
M79.06 Rheumatism, unspecified (Lower leg)
0.689 0.311 0.000
M79.05 Rheumatism, unspecified (Pelvic region and thigh)
0.689 0.311 0.000
M79.04 Rheumatism, unspecified (Hand)
0.689 0.311 0.000
M79.03 Rheumatism, unspecified (Forearm)
0.689 0.311 0.000
M79.02 Rheumatism, unspecified (Upper arm)
0.689 0.311 0.000
M79.01 Rheumatism, unspecified (Shoulder region)
0.689 0.311 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.688 0.311 0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)
0.688 0.312 0.000
S06.8 Other intracranial injuries
0.688 0.312 0.000
X10-X19 Contact with heat and hot substances
0.688 0.312 0.000
T20 Burn and corrosion of head and neck
0.687 0.312 0.000
M43.0 Spondylolysis
0.687 0.313 0.000
M54.0 Panniculitis affecting regions of neck and back
0.685 0.315 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.684 0.316 0.000
M42 Spinal osteochondrosis
0.684 0.316 0.000
T23 Burn and corrosion of wrist and hand
0.684 0.316 0.000
S08 Traumatic amputation of part of head
0.683 0.317 0.000
S07 Crushing injury of head
0.683 0.317 0.000
S04 Injury of cranial nerves
0.683 0.317 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.683 0.317 0.000
G30.8 Other Alzheimer's disease
0.683 0.317 0.000
G30.1 Alzheimer's disease with late onset
0.683 0.317 0.000
M88 Paget's disease of bone [osteitis deformans]
0.683 0.317 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.682 0.318 0.000
F23.0 Acute polymorphic psychotic disorder without symptoms of schizophrenia
0.682 0.318 0.000
W19.8 Other specified place
0.681 0.318 0.000
W19.5 Trade and service area
0.681 0.318 0.000
W19.0 Home
0.681 0.318 0.000
W19.7 Farm
0.681 0.318 0.000
W19.6 Industrial and construction area
0.681 0.318 0.000
M25.9 Joint disorder, unspecified
0.681 0.319 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.681 0.319 0.000
M70.4 Prepatellar bursitis
0.681 0.319 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.681 0.319 0.000
M75 Shoulder lesions
0.681 0.319 0.000
M70.5 Other bursitis of knee
0.680 0.320 0.000
Y54.3 Benzothiadiazine derivatives
0.680 0.320 0.000
S06.30 Focal brain injury (without open intracranial wound)
0.680 0.320 0.000
F00.2 Dementia in Alzheimer's disease, atypical or mixed type
0.679 0.320 0.000
F00.1 Dementia in Alzheimer's disease with late onset
0.679 0.320 0.000
F00.0 Dementia in Alzheimer's disease with early onset
0.679 0.320 0.000
V28 Motorcycle rider injured in noncollision transport accident
0.679 0.321 0.000
T21 Burn and corrosion of trunk
0.679 0.321 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.678 0.322 0.000
S22.1 Multiple fractures of thoracic spine
0.678 0.322 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.678 0.322 0.000
M53.3 Sacrococcygeal disorders, not elsewhere classified
0.677 0.323 0.000
F32.0 Mild depressive episode
0.677 0.323 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.676 0.324 0.000
S06.9 Intracranial injury, unspecified
0.676 0.324 0.000
M49 Spondylopathies in diseases classified elsewhere
0.675 0.324 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.675 0.325 0.000
W44.0 Home
0.675 0.325 0.000
T09 Other injuries of spine and trunk, level unspecified
0.673 0.327 0.000
T12.X1 Fracture of lower limb, level unspecified (open)
0.673 0.327 0.000
T12.X0 Fracture of lower limb, level unspecified (closed)
0.673 0.327 0.000
T12 Fracture of lower limb, level unspecified
0.673 0.327 0.000
T10.X1 Fracture of upper limb, level unspecified (open)
0.673 0.327 0.000
T10.X0 Fracture of upper limb, level unspecified (closed)
0.673 0.327 0.000
T10 Fracture of upper limb, level unspecified
0.673 0.327 0.000
T08.X1 Fracture of spine, level unspecified (open)
0.673 0.327 0.000
T08.X0 Fracture of spine, level unspecified (closed)
0.673 0.327 0.000
T08 Fracture of spine, level unspecified
0.673 0.327 0.000
M70.9 Unspecified soft tissue disorder related to use, overuse and pressure
0.673 0.327 0.000
M70.8 Other soft tissue disorders related to use, overuse and pressure
0.673 0.327 0.000
M70.7 Other bursitis of hip
0.673 0.327 0.000
M70.3 Other bursitis of elbow
0.673 0.327 0.000
M70.1 Bursitis of hand
0.673 0.327 0.000
M70.0 Chronic crepitant synovitis of hand and wrist
0.673 0.327 0.000
M70.2 Olecranon bursitis
0.673 0.327 0.000
W45.8 Other specified place
0.672 0.328 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.672 0.328 0.000
F60.7 Dependent personality disorder
0.672 0.328 0.000
Y49.5 Other antipsychotics and neuroleptics
0.671 0.329 0.000
S00.8 Superficial injury of other parts of head
0.671 0.329 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.671 0.329 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.669 0.331 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.668 0.332 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.668 0.332 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.668 0.332 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.668 0.332 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.668 0.332 0.000
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)
0.667 0.333 0.000
V80-V89 Other land transport accidents
0.667 0.333 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.667 0.333 0.000
S22.0 Fracture of thoracic vertebra
0.666 0.334 0.000
S06.7 Intracranial injury with prolonged coma
0.666 0.334 0.000
S06.1 Traumatic cerebral oedema
0.666 0.334 0.000
F28 Other nonorganic psychotic disorders
0.665 0.335 0.000
F24 Induced delusional disorder
0.665 0.335 0.000
F21 Schizotypal disorder
0.665 0.335 0.000
G62.2 Polyneuropathy due to other toxic agents
0.665 0.335 0.000
G62.1 Alcoholic polyneuropathy
0.665 0.335 0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.664 0.335 0.000
W14.9 Unspecified place
0.664 0.336 0.000
W46 Contact with hypodermic needle
0.664 0.336 0.000
W43 Exposure to vibration
0.664 0.336 0.000
W42 Exposure to noise
0.664 0.336 0.000
W41 Exposure to high-pressure jet
0.664 0.336 0.000
W40 Explosion of other materials
0.664 0.336 0.000
W39 Discharge of firework
0.664 0.336 0.000
W38 Explosion and rupture of other specified pressurised devices
0.664 0.336 0.000
W37 Explosion and rupture of pressurised tyre, pipe or hose
0.664 0.336 0.000
W36 Explosion and rupture of gas cylinder
0.664 0.336 0.000
W35 Explosion and rupture of boiler
0.664 0.336 0.000
W34 Discharge from other and unspecified firearms
0.664 0.336 0.000
W33 Rifle, shotgun and larger firearm discharge
0.664 0.336 0.000
W32 Handgun discharge
0.664 0.336 0.000
W31 Contact with other and unspecified machinery
0.664 0.336 0.000
W30 Contact with agricultural machinery
0.664 0.336 0.000
W27 Contact with nonpowered hand tool
0.664 0.336 0.000
W26 Contact with knife, sword or dagger
0.664 0.336 0.000
W24 Contact with lifting and transmission devices, not elsewhere classified
0.664 0.336 0.000
W23 Caught, crushed, jammed or pinched in or between objects
0.664 0.336 0.000
M34.9 Systemic sclerosis, unspecified
0.663 0.337 0.000
S22.5 Flail chest
0.663 0.337 0.000
M24 Other specific joint derangements
0.662 0.338 0.000
G37.8 Other specified demyelinating diseases of central nervous system
0.662 0.338 0.000
G37.5 Concentric sclerosis [Balo]
0.662 0.338 0.000
G37.4 Subacute necrotising myelitis
0.662 0.338 0.000
G37.2 Central pontine myelinolysis
0.662 0.338 0.000
G37.1 Central demyelination of corpus callosum
0.662 0.338 0.000
G37.0 Diffuse sclerosis
0.662 0.338 0.000
F68 Other disorders of adult personality and behaviour
0.662 0.338 0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation
0.662 0.338 0.000
F65 Disorders of sexual preference
0.662 0.338 0.000
F63 Habit and impulse disorders
0.662 0.338 0.000
F62 Enduring personality changes, not attributable to brain damage and disease
0.662 0.338 0.000
F61 Mixed and other personality disorders
0.662 0.338 0.000
F25.1 Schizoaffective disorder, depressive type
0.662 0.338 0.000
W17.4 Street and highway
0.661 0.339 0.000
Q50-Q56 Congenital malformations of genital organs
0.661 0.339 0.000
M48 Other spondylopathies
0.660 0.340 0.000
M25.4 Effusion of joint
0.660 0.340 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.660 0.340 0.000
S11 Open wound of neck
0.660 0.340 0.000
Q60-Q64 Congenital malformations of the urinary system
0.659 0.341 0.000
W50-W64 Exposure to animate mechanical forces
0.659 0.341 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.658 0.342 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.658 0.342 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.658 0.342 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.658 0.342 0.000
T36 Poisoning by systemic antibiotics
0.658 0.342 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.657 0.343 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.656 0.344 0.000
M79.68 Pain in limb (Other)
0.655 0.345 0.000
T14.1 Open wound of unspecified body region
0.655 0.345 0.000
W22.3 Sports and athletics area
0.655 0.345 0.000
S20.1 Other and unspecified superficial injuries of breast
0.655 0.345 0.000
M32 Systemic lupus erythematosus
0.654 0.346 0.000
M83 Adult osteomalacia
0.654 0.346 0.000
M77.9 Enthesopathy, unspecified
0.654 0.346 0.000
M41.96 Scoliosis, unspecified (Lumbar region)
0.654 0.346 0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)
0.654 0.346 0.000
S78 Traumatic amputation of hip and thigh
0.653 0.346 0.000
S77 Crushing injury of hip and thigh
0.653 0.346 0.000
S75 Injury of blood vessels at hip and thigh level
0.653 0.346 0.000
S74 Injury of nerves at hip and thigh level
0.653 0.346 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.653 0.347 0.000
M84.8 Other disorders of continuity of bone
0.653 0.347 0.000
W20 Struck by thrown, projected or falling object
0.652 0.347 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.652 0.348 0.000
T39.4 Antirheumatics, not elsewhere classified
0.652 0.348 0.000
T39.2 Pyrazolone derivatives
0.652 0.348 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.651 0.349 0.000
T86 Failure and rejection of transplanted organs and tissues
0.651 0.349 0.000
S22.9 Fracture of bony thorax, part unspecified
0.650 0.350 0.000
S22.8 Fracture of other parts of bony thorax
0.650 0.350 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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