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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12508440
log Bayes Factor = 5.68351
Chromosome 4   position 62,487,133  (GRCh37) Explore rs12508440 on Ensembl!
Variant rs12508440 is part of Cluster X0269

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
I20-I25 Ischaemic heart diseases
0.999 0.001 0.000
Chapter VIII Diseases of the ear and mastoid process
0.998 0.002 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.997 0.003 0.000
E10-E14 Diabetes mellitus
0.990 0.010 0.000
Chapter XX External causes of morbidity and mortality
0.984 0.016 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.983 0.017 0.000
I25 Chronic ischaemic heart disease
0.981 0.019 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.980 0.020 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.980 0.020 0.000
H90-H95 Other disorders of ear
0.978 0.022 0.000
I20 Angina pectoris
0.973 0.027 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.973 0.027 0.000
E65-E68 Obesity and other hyperalimentation
0.972 0.028 0.000
I22 Subsequent myocardial infarction
0.968 0.032 0.000
E14 Unspecified diabetes mellitus
0.964 0.036 0.000
H65-H75 Diseases of middle ear and mastoid
0.960 0.040 0.000
I25.2 Old myocardial infarction
0.958 0.042 0.000
I95 Hypotension
0.955 0.045 0.000
M80-M85 Disorders of bone density and structure
0.953 0.047 0.000
I20.9 Angina pectoris, unspecified
0.952 0.048 0.000
S40-S49 Injuries to the shoulder and upper arm
0.952 0.048 0.000
E66 Obesity
0.952 0.048 0.000
Chapter V Mental and behavioural disorders
0.951 0.049 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.948 0.052 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.948 0.052 0.000
E14.9 Without complications
0.948 0.052 0.000
Chapter VII Diseases of the eye and adnexa
0.945 0.055 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.944 0.056 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.942 0.058 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.940 0.060 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.940 0.060 0.000
E66.9 Obesity, unspecified
0.938 0.062 0.000
M05-M14 Inflammatory polyarthropathies
0.936 0.064 0.000
Chapter I Certain infectious and parasitic diseases
0.932 0.068 0.000
H92 Otalgia and effusion of ear
0.931 0.069 0.000
T42.4 Benzodiazepines
0.921 0.079 0.000
H30-H36 Disorders of choroid and retina
0.921 0.079 0.000
H93 Other disorders of ear, not elsewhere classified
0.903 0.097 0.000
Chapter X Diseases of the respiratory system
0.902 0.098 0.000
M81 Osteoporosis without pathological fracture
0.894 0.106 0.000
E11 Non-insulin-dependent diabetes mellitus
0.893 0.107 0.000
H65 Nonsuppurative otitis media
0.888 0.112 0.000
F60-F69 Disorders of adult personality and behaviour
0.885 0.115 0.000
I95.8 Other hypotension
0.883 0.117 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.880 0.120 0.000
E50-E64 Other nutritional deficiencies
0.880 0.120 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.877 0.123 0.000
T51 Toxic effect of alcohol
0.876 0.124 0.000
V20-V29 Motorcycle rider injured in transport accident
0.874 0.126 0.000
J09-J18 Influenza and pneumonia
0.874 0.126 0.000
T79-T79 Certain early complications of trauma
0.872 0.128 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.872 0.128 0.000
H40-H42 Glaucoma
0.870 0.130 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.870 0.130 0.000
S40 Superficial injury of shoulder and upper arm
0.867 0.133 0.000
H53-H54 Visual disturbances and blindness
0.867 0.133 0.000
B95-B98 Bacterial, viral and other infectious agents
0.866 0.134 0.000
M81.9 Osteoporosis, unspecified
0.862 0.138 0.000
I95.1 Orthostatic hypotension
0.862 0.138 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.857 0.143 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.856 0.144 0.000
I99 Other and unspecified disorders of circulatory system
0.854 0.146 0.000
M70-M79 Other soft tissue disorders
0.853 0.147 0.000
M10 Gout
0.852 0.148 0.000
M80 Osteoporosis with pathological fracture
0.852 0.148 0.000
W00-W19 Falls
0.849 0.151 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.849 0.151 0.000
H34 Retinal vascular occlusions
0.846 0.154 0.000
Q80-Q89 Other congenital malformations
0.844 0.156 0.000
H36 Retinal disorders in diseases classified elsewhere
0.844 0.156 0.000
H93.1 Tinnitus
0.843 0.157 0.000
H80-H83 Diseases of inner ear
0.842 0.158 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.842 0.158 0.000
H54 Blindness and low vision
0.842 0.158 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.841 0.159 0.000
M11 Other crystal arthropathies
0.841 0.159 0.000
J40-J47 Chronic lower respiratory diseases
0.839 0.161 0.000
A30-A49 Other bacterial diseases
0.838 0.162 0.000
H92.1 Otorrhoea
0.837 0.163 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.837 0.163 0.000
H31 Other disorders of choroid
0.831 0.169 0.000
H54.4 Blindness, one eye
0.829 0.171 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.826 0.174 0.000
J44 Other chronic obstructive pulmonary disease
0.825 0.175 0.000
M60-M63 Disorders of muscles
0.824 0.176 0.000
E11.3 With ophthalmic complications
0.821 0.179 0.000
T56 Toxic effect of metals
0.819 0.181 0.000
H40 Glaucoma
0.817 0.183 0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters
0.816 0.184 0.000
F60 Specific personality disorders
0.815 0.185 0.000
M79.8 Other specified soft tissue disorders
0.815 0.185 0.000
I77 Other disorders of arteries and arterioles
0.813 0.187 0.000
F20 Schizophrenia
0.810 0.190 0.000
Q50-Q56 Congenital malformations of genital organs
0.809 0.190 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.809 0.191 0.000
F30-F39 Mood [affective] disorders
0.807 0.193 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.805 0.195 0.000
H40.9 Glaucoma, unspecified
0.802 0.198 0.000
M91-M94 Chondropathies
0.801 0.199 0.000
T51.9 Alcohol, unspecified
0.801 0.199 0.000
M05 Seropositive rheumatoid arthritis
0.800 0.200 0.000
I20.1 Angina pectoris with documented spasm
0.799 0.201 0.000
B99-B99 Other infectious diseases
0.799 0.201 0.000
J18 Pneumonia, organism unspecified
0.798 0.202 0.000
H65.3 Chronic mucoid otitis media
0.797 0.203 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.795 0.205 0.000
S46.0 Injury of tendon of the rotator cuff of shoulder
0.795 0.205 0.000
I20.0 Unstable angina
0.794 0.206 0.000
I24 Other acute ischaemic heart diseases
0.794 0.206 0.000
E13 Other specified diabetes mellitus
0.790 0.210 0.000
V80-V89 Other land transport accidents
0.789 0.211 0.000
H34.2 Other retinal artery occlusions
0.788 0.212 0.000
H36.0 Diabetic retinopathy
0.788 0.212 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.786 0.214 0.000
M10.9 Gout, unspecified
0.785 0.215 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.784 0.216 0.000
H69 Other disorders of Eustachian tube
0.782 0.218 0.000
H92.0 Otalgia
0.781 0.219 0.000
H71 Cholesteatoma of middle ear
0.781 0.219 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.779 0.221 0.000
V40-V49 Car occupant injured in transport accident
0.778 0.222 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.776 0.224 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.775 0.225 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.775 0.225 0.000
A40 Streptococcal septicaemia
0.774 0.226 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.774 0.226 0.000
M11.2 Other chondrocalcinosis
0.773 0.227 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.773 0.227 0.000
M40-M43 Deforming dorsopathies
0.772 0.228 0.000
S40.8 Other superficial injuries of shoulder and upper arm
0.771 0.229 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.771 0.229 0.000
E11.8 With unspecified complications
0.770 0.230 0.000
Q82 Other congenital malformations of skin
0.770 0.230 0.000
I25.3 Aneurysm of heart
0.769 0.231 0.000
M86-M90 Other osteopathies
0.768 0.232 0.000
I95.9 Hypotension, unspecified
0.768 0.232 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.767 0.233 0.000
B97.8 Other viral agents as the cause of diseases classified to other chapters
0.764 0.236 0.000
H92.2 Otorrhagia
0.763 0.237 0.000
H72 Perforation of tympanic membrane
0.762 0.238 0.000
H90 Conductive and sensorineural hearing loss
0.761 0.239 0.000
J43 Emphysema
0.758 0.242 0.000
J10 Influenza due to identified influenza virus
0.757 0.243 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.752 0.248 0.000
I25.4 Coronary artery aneurysm
0.751 0.249 0.000
F60.3 Emotionally unstable personality disorder
0.749 0.251 0.000
M10.96 Gout, unspecified (Lower leg)
0.749 0.251 0.000
F80-F89 Disorders of psychological development
0.748 0.252 0.000
S10-S19 Injuries to the neck
0.748 0.252 0.000
H55-H59 Other disorders of eye and adnexa
0.748 0.252 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.747 0.253 0.000
S40.0 Contusion of shoulder and upper arm
0.747 0.253 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.747 0.253 0.000
H10-H13 Disorders of conjunctiva
0.747 0.253 0.000
E10 Insulin-dependent diabetes mellitus
0.746 0.254 0.000
Y10-Y34 Event of undetermined intent
0.745 0.255 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.745 0.255 0.000
W50-W64 Exposure to animate mechanical forces
0.744 0.256 0.000
J17 Pneumonia in diseases classified elsewhere
0.743 0.257 0.000
F20.0 Paranoid schizophrenia
0.743 0.257 0.000
X60-X84 Intentional self-harm
0.742 0.258 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.741 0.259 0.000
M50-M54 Other dorsopathies
0.739 0.261 0.000
W08 Fall involving other furniture
0.736 0.264 0.000
B35-B49 Mycoses
0.736 0.264 0.000
H81 Disorders of vestibular function
0.736 0.264 0.000
V10-V19 Pedal cyclist injured in transport accident
0.735 0.265 0.000
A40.8 Other streptococcal septicaemia
0.734 0.266 0.000
H31.0 Chorioretinal scars
0.734 0.266 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.733 0.267 0.000
T56.8 Other metals
0.732 0.268 0.000
E55 Vitamin D deficiency
0.732 0.268 0.000
E11.6 With other specified complications
0.730 0.270 0.000
M79.1 Myalgia
0.730 0.270 0.000
M79.0 Rheumatism, unspecified
0.730 0.270 0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van
0.729 0.271 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.729 0.271 0.000
W20-W49 Exposure to inanimate mechanical forces
0.729 0.271 0.000
Y48 Anaesthetics and therapeutic gases
0.728 0.272 0.000
I72 Other aneurysm
0.726 0.274 0.000
E65 Localised adiposity
0.726 0.274 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.725 0.275 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.724 0.276 0.000
M11.26 Other chondrocalcinosis (Lower leg)
0.724 0.276 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.724 0.276 0.000
M80.0 Postmenopausal osteoporosis with pathological fracture
0.722 0.278 0.000
T51.0 Ethanol
0.722 0.278 0.000
S42 Fracture of shoulder and upper arm
0.722 0.278 0.000
F31 Bipolar affective disorder
0.722 0.278 0.000
E14.4 With neurological complications
0.722 0.278 0.000
M84 Disorders of continuity of bone
0.721 0.279 0.000
X50-X57 Overexertion, travel and privation
0.721 0.279 0.000
H65.9 Nonsuppurative otitis media, unspecified
0.721 0.279 0.000
J18.1 Lobar pneumonia, unspecified
0.721 0.279 0.000
I23 Certain current complications following acute myocardial infarction
0.720 0.280 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.719 0.281 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.716 0.283 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.716 0.284 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.715 0.285 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.715 0.285 0.000
E20-E35 Disorders of other endocrine glands
0.710 0.290 0.000
H70 Mastoiditis and related conditions
0.710 0.290 0.000
E12 Malnutrition-related diabetes mellitus
0.709 0.290 0.000
I78 Diseases of capillaries
0.708 0.292 0.000
M94 Other disorders of cartilage
0.708 0.292 0.000
I10-I15 Hypertensive diseases
0.707 0.293 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.706 0.293 0.000
Y00-Y09 Assault
0.706 0.294 0.000
H65.2 Chronic serous otitis media
0.706 0.294 0.000
Y35-Y36 Legal intervention and operations of war
0.706 0.294 0.000
X85-X99 Assault
0.706 0.294 0.000
X30-X39 Exposure to forces of nature
0.706 0.294 0.000
X00-X09 Exposure to smoke, fire and flames
0.706 0.294 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.706 0.294 0.000
W75-W84 Other accidental threats to breathing
0.706 0.294 0.000
W65-W74 Accidental drowning and submersion
0.706 0.294 0.000
V98-V99 Other and unspecified transport accidents
0.706 0.294 0.000
V95-V97 Air and space transport accidents
0.706 0.294 0.000
V90-V94 Water transport accidents
0.706 0.294 0.000
V70-V79 Bus occupant injured in transport accident
0.706 0.294 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.706 0.294 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.706 0.294 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.706 0.294 0.000
V01-V09 Pedestrian injured in transport accident
0.706 0.294 0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.705 0.295 0.000
H54.7 Unspecified visual loss
0.705 0.295 0.000
T36 Poisoning by systemic antibiotics
0.704 0.296 0.000
I25.6 Silent myocardial ischaemia
0.704 0.296 0.000
Y40 Systemic antibiotics
0.704 0.296 0.000
T58 Toxic effect of carbon monoxide
0.703 0.297 0.000
E53 Deficiency of other B group vitamins
0.703 0.297 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.703 0.297 0.000
B99 Other and unspecified infectious diseases
0.703 0.297 0.000
T33-T35 Frostbite
0.703 0.297 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.703 0.297 0.000
T79.7 Traumatic subcutaneous emphysema
0.701 0.299 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.701 0.299 0.000
V22 Motorcycle rider injured in collision with two- or three-wheeled motor vehicle
0.701 0.299 0.000
B65-B83 Helminthiases
0.701 0.299 0.000
H30 Chorioretinal inflammation
0.698 0.302 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.697 0.302 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.697 0.302 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.697 0.302 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.697 0.302 0.000
J46 Status asthmaticus
0.697 0.303 0.000
M79.5 Residual foreign body in soft tissue
0.697 0.303 0.000
X10-X19 Contact with heat and hot substances
0.697 0.303 0.000
E67 Other hyperalimentation
0.697 0.303 0.000
E68 Sequelae of hyperalimentation
0.697 0.303 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.696 0.304 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.695 0.305 0.000
H34.1 Central retinal artery occlusion
0.694 0.306 0.000
J18.8 Other pneumonia, organism unspecified
0.694 0.306 0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)
0.693 0.306 0.000
J43.9 Emphysema, unspecified
0.693 0.307 0.000
A15-A19 Tuberculosis
0.692 0.308 0.000
M62 Other disorders of muscle
0.692 0.308 0.000
E11.1 With ketoacidosis
0.692 0.308 0.000
E14.8 With unspecified complications
0.691 0.309 0.000
E14.7 With multiple complications
0.691 0.309 0.000
E14.6 With other specified complications
0.691 0.309 0.000
E14.5 With peripheral circulatory complications
0.691 0.309 0.000
E14.2 Withrenal complications
0.691 0.309 0.000
E14.1 With ketoacidosis
0.691 0.309 0.000
E14.0 With coma
0.691 0.309 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.691 0.309 0.000
A48 Other bacterial diseases, not elsewhere classified
0.690 0.310 0.000
M06 Other rheumatoid arthritis
0.689 0.311 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.688 0.311 0.000
H68 Eustachian salpingitis and obstruction
0.688 0.311 0.000
H67 Otitis media in diseases classified elsewhere
0.688 0.311 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.688 0.312 0.000
Q82.8 Other specified congenital malformations of skin
0.687 0.313 0.000
F64 Gender identity disorders
0.687 0.313 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.687 0.313 0.000
T00-T07 Injuries involving multiple body regions
0.687 0.313 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.686 0.314 0.000
V28 Motorcycle rider injured in noncollision transport accident
0.685 0.315 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.684 0.316 0.000
I95.2 Hypotension due to drugs
0.684 0.316 0.000
F30 Manic episode
0.684 0.316 0.000
M83 Adult osteomalacia
0.683 0.317 0.000
S48 Traumatic amputation of shoulder and upper arm
0.682 0.317 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.682 0.317 0.000
S44 Injury of nerves at shoulder and upper arm level
0.682 0.317 0.000
S47 Crushing injury of shoulder and upper arm
0.682 0.317 0.000
E66.1 Drug-induced obesity
0.682 0.318 0.000
E66.0 Obesity due to excess calories
0.682 0.318 0.000
H60-H62 Diseases of external ear
0.682 0.318 0.000
M00-M03 Infectious arthropathies
0.682 0.318 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.682 0.318 0.000
F70-F79 Mental retardation
0.682 0.318 0.000
T59 Toxic effect of other gases, fumes and vapours
0.680 0.319 0.000
E61 Deficiency of other nutrient elements
0.680 0.320 0.000
W17 Other fall from one level to another
0.680 0.320 0.000
M79.89 Other specified soft tissue disorders (Site unspecified)
0.680 0.320 0.000
T45.0 Antiallergic and antiemetic drugs
0.679 0.321 0.000
Q53 Undescended testicle
0.679 0.321 0.000
X20-X29 Contact with venomous animals and plants
0.678 0.321 0.000
I25.5 Ischaemic cardiomyopathy
0.677 0.322 0.000
I72.0 Aneurysm of carotid artery
0.677 0.323 0.000
M82 Osteoporosis in diseases classified elsewhere
0.677 0.323 0.000
Q35-Q37 Cleft lip and cleft palate
0.677 0.323 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.677 0.323 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.677 0.323 0.000
H93.8 Other specified disorders of ear
0.676 0.324 0.000
F99-F99 Unspecified mental disorder
0.676 0.324 0.000
J86 Pyothorax
0.676 0.324 0.000
F69 Unspecified disorder of adult personality and behaviour
0.676 0.324 0.000
T43.9 Psychotropic drug, unspecified
0.675 0.325 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.675 0.325 0.000
T43.6 Psychostimulants with abuse potential
0.675 0.325 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.675 0.325 0.000
B50-B64 Protozoal diseases
0.674 0.326 0.000
T65 Toxic effect of other and unspecified substances
0.674 0.326 0.000
T62 Toxic effect of other noxious substances eaten as food
0.674 0.326 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.674 0.326 0.000
T60 Toxic effect of pesticides
0.674 0.326 0.000
T57 Toxic effect of other inorganic substances
0.674 0.326 0.000
T54 Toxic effect of corrosive substances
0.674 0.326 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.674 0.326 0.000
T52 Toxic effect of organic solvents
0.674 0.326 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.674 0.326 0.000
T55 Toxic effect of soaps and detergents
0.674 0.326 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.674 0.326 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.674 0.326 0.000
T42.3 Barbiturates
0.674 0.326 0.000
T42.2 Succinimides and oxazolidinediones
0.674 0.326 0.000
T42.0 Hydantoin derivatives
0.674 0.326 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.674 0.326 0.000
H31.8 Other specified disorders of choroid
0.673 0.327 0.000
H74 Other disorders of middle ear and mastoid
0.673 0.327 0.000
H73 Other disorders of tympanic membrane
0.672 0.328 0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture
0.671 0.328 0.000
M12 Other specific arthropathies
0.671 0.329 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.671 0.329 0.000
M08 Juvenile arthritis
0.671 0.329 0.000
J20-J22 Other acute lower respiratory infections
0.671 0.329 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.668 0.331 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.668 0.331 0.000
A75-A79 Rickettsioses
0.668 0.331 0.000
A70-A74 Other diseases caused by chlamydiae
0.668 0.331 0.000
A65-A69 Other spirochaetal diseases
0.668 0.331 0.000
A20-A28 Certain zoonotic bacterial diseases
0.668 0.331 0.000
Q96 Turner's syndrome
0.668 0.331 0.000
M79.00 Rheumatism, unspecified (Multiple sites)
0.668 0.332 0.000
I95.0 Idiopathic hypotension
0.668 0.332 0.000
S43.0 Dislocation of shoulder joint
0.668 0.332 0.000
E16 Other disorders of pancreatic internal secretion
0.668 0.332 0.000
M51 Other intervertebral disk disorders
0.667 0.333 0.000
H69.9 Eustachian tube disorder, unspecified
0.666 0.334 0.000
H72.0 Central perforation of tympanic membrane
0.666 0.334 0.000
J18.0 Bronchopneumonia, unspecified
0.664 0.336 0.000
I05-I09 Chronic rheumatic heart diseases
0.664 0.336 0.000
T98 Sequelae of other and unspecified effects of external causes
0.664 0.336 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.664 0.336 0.000
S90-S99 Injuries to the ankle and foot
0.663 0.337 0.000
Q83 Congenital malformations of breast
0.663 0.337 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.662 0.338 0.000
M07 Psoriatic and enteropathic arthropathies
0.662 0.338 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.661 0.339 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.660 0.340 0.000
M81.98 Osteoporosis, unspecified (Other)
0.660 0.340 0.000
H81.0 Meniere's disease
0.660 0.340 0.000
F29 Unspecified nonorganic psychosis
0.660 0.340 0.000
Y54.3 Benzothiadiazine derivatives
0.658 0.342 0.000
F20.9 Schizophrenia, unspecified
0.658 0.342 0.000
T45.5 Anticoagulants
0.657 0.343 0.000
J17.0 Pneumonia in bacterial diseases classified elsewhere
0.657 0.343 0.000
W10 Fall on and from stairs and steps
0.656 0.344 0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.656 0.344 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.656 0.344 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.655 0.344 0.000
W08.0 Home
0.655 0.345 0.000
H40.1 Primary open-angle glaucoma
0.655 0.345 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.655 0.345 0.000
A80-A89 Viral infections of the central nervous system
0.654 0.345 0.000
J60-J70 Lung diseases due to external agents
0.654 0.346 0.000
Chapter XXII Codes for special purposes
0.654 0.346 0.000
M85 Other disorders of bone density and structure
0.653 0.347 0.000
H66 Suppurative and unspecified otitis media
0.653 0.347 0.000
J10.0 Influenza with pneumonia, influenza virus identified
0.652 0.348 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.652 0.348 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.652 0.348 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.651 0.349 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.650 0.349 0.000
F23 Acute and transient psychotic disorders
0.650 0.350 0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified
0.649 0.351 0.000
M89 Other disorders of bone
0.649 0.351 0.000
A49 Bacterial infection of unspecified site
0.648 0.352 0.000
I24.8 Other forms of acute ischaemic heart disease
0.648 0.352 0.000
H93.9 Disorder of ear, unspecified
0.648 0.352 0.000
H93.3 Disorders of acoustic nerve
0.648 0.352 0.000
H93.2 Other abnormal auditory perceptions
0.648 0.352 0.000
H93.0 Degenerative and vascular disorders of ear
0.648 0.352 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.647 0.352 0.000
E13.9 Without complications
0.647 0.353 0.000
I77.0 Arteriovenous fistula, acquired
0.645 0.355 0.000
S41 Open wound of shoulder and upper arm
0.645 0.355 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.645 0.355 0.000
I70 Atherosclerosis
0.644 0.356 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.643 0.357 0.000
Q00-Q07 Congenital malformations of the nervous system
0.642 0.357 0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)
0.642 0.358 0.000
F22 Persistent delusional disorders
0.642 0.358 0.000
M81.8 Other osteoporosis
0.641 0.359 0.000
M81.6 Localised osteoporosis [Lequesne]
0.641 0.359 0.000
M81.5 Idiopathic osteoporosis
0.641 0.359 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.641 0.359 0.000
M81.1 Postoophorectomy osteoporosis
0.641 0.359 0.000
M81.0 Postmenopausal osteoporosis
0.641 0.359 0.000
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances
0.641 0.359 0.000
E11.7 With multiple complications
0.640 0.359 0.000
T63 Toxic effect of contact with venomous animals
0.640 0.360 0.000
E11.0 With coma
0.639 0.361 0.000
F60.9 Personality disorder, unspecified
0.639 0.361 0.000
M10.0 Idiopathic gout
0.639 0.361 0.000
E66.8 Other obesity
0.638 0.362 0.000
B15-B19 Viral hepatitis
0.637 0.363 0.000
M79.80 Other specified soft tissue disorders (Multiple sites)
0.637 0.363 0.000
H65.1 Other acute nonsuppurative otitis media
0.636 0.364 0.000
H65.0 Acute serous otitis media
0.636 0.364 0.000
F68 Other disorders of adult personality and behaviour
0.635 0.365 0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation
0.635 0.365 0.000
F65 Disorders of sexual preference
0.635 0.365 0.000
F63 Habit and impulse disorders
0.635 0.365 0.000
F62 Enduring personality changes, not attributable to brain damage and disease
0.635 0.365 0.000
F61 Mixed and other personality disorders
0.635 0.365 0.000
M43 Other deforming dorsopathies
0.635 0.365 0.000
F39 Unspecified mood [affective] disorder
0.634 0.366 0.000
Y43 Primarily systemic agents
0.634 0.366 0.000
W11 Fall on and from ladder
0.634 0.366 0.000
H72.1 Attic perforation of tympanic membrane
0.634 0.366 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.634 0.366 0.000
I22.8 Subsequent myocardial infarction of other sites
0.633 0.367 0.000
T79.5 Traumatic anuria
0.633 0.367 0.000
Q54 Hypospadias
0.632 0.368 0.000
Y59 Other and unspecified vaccines and biological substances
0.631 0.369 0.000
Y58 Bacterial vaccines
0.631 0.369 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.631 0.369 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.631 0.369 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.631 0.369 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.631 0.369 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.631 0.369 0.000
E63 Other nutritional deficiencies
0.631 0.369 0.000
E56 Other vitamin deficiencies
0.631 0.369 0.000
E51 Thiamine deficiency
0.631 0.369 0.000
E50 Vitamin A deficiency
0.631 0.369 0.000
E60 Dietary zinc deficiency
0.631 0.369 0.000
E59 Dietary selenium deficiency
0.631 0.369 0.000
E58 Dietary calcium deficiency
0.631 0.369 0.000
E54 Ascorbic acid deficiency
0.631 0.369 0.000
E52 Niacin deficiency [pellagra]
0.631 0.369 0.000
A39 Meningococcal infection
0.631 0.369 0.000
Q82.5 Congenital nonneoplastic naevus
0.630 0.370 0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)
0.629 0.371 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.629 0.371 0.000
H90.2 Conductive hearing loss, unspecified
0.628 0.372 0.000
T51.8 Other alcohols
0.628 0.372 0.000
T51.3 Fusel oil
0.628 0.372 0.000
T51.2 2-Propanol
0.628 0.372 0.000
T51.1 Methanol
0.628 0.372 0.000
H33 Retinal detachments and breaks
0.627 0.373 0.000
V29 Motorcycle rider injured in other and unspecified transport accidents
0.627 0.373 0.000
V26 Motorcycle rider injured in collision with other nonmotor vehicle
0.627 0.373 0.000
V25 Motorcycle rider injured in collision with railway train or railway vehicle
0.627 0.373 0.000
V24 Motorcycle rider injured in collision with heavy transport vehicle or bus
0.627 0.373 0.000
V21 Motorcycle rider injured in collision with pedal cycle
0.627 0.373 0.000
V20 Motorcycle rider injured in collision with pedestrian or animal
0.627 0.373 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.626 0.373 0.000
J12 Viral pneumonia, not elsewhere classified
0.626 0.373 0.000
J09 Influenza due to certain identified influenza virus
0.626 0.373 0.000
W18 Other fall on same level
0.626 0.374 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.626 0.374 0.000
V23.4 Driver injured in traffic accident
0.626 0.374 0.000
E55.9 Vitamin D deficiency, unspecified
0.625 0.375 0.000
M79.2 Neuralgia and neuritis, unspecified
0.625 0.375 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.625 0.375 0.000
F28 Other nonorganic psychotic disorders
0.625 0.375 0.000
F24 Induced delusional disorder
0.625 0.375 0.000
F21 Schizotypal disorder
0.625 0.375 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.625 0.375 0.000
Y44 Agents primarily affecting blood constituents
0.625 0.375 0.000
M60 Myositis
0.625 0.375 0.000
V48 Car occupant injured in noncollision transport accident
0.625 0.375 0.000
M14 Arthropathies in other diseases classified elsewhere
0.624 0.376 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.624 0.376 0.000
H42 Glaucoma in diseases classified elsewhere
0.624 0.376 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.624 0.376 0.000
H11 Other disorders of conjunctiva
0.623 0.377 0.000
M10.90 Gout, unspecified (Multiple sites)
0.623 0.377 0.000
M51.8 Other specified intervertebral disk disorders
0.622 0.378 0.000
V27 Motorcycle rider injured in collision with fixed or stationary object
0.622 0.378 0.000
S40.7 Multiple superficial injuries of shoulder and upper arm
0.622 0.378 0.000
M81.2 Osteoporosis of disuse
0.621 0.379 0.000
M79.10 Myalgia (Multiple sites)
0.620 0.380 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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