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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12910916
log Bayes Factor = 24.3202
Chromosome 15   position 47,675,655  (GRCh37) Explore rs12910916 on Ensembl!
Variant rs12910916 is part of Cluster X0332

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
F10-F19 Mental and behavioural disorders due to psychoactive substance use
1.000 0.000 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
N18 Chronic renal failure
0.999 0.001 0.000
N17-N19 Renal failure
0.999 0.001 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.999 0.001 0.000
F17.1 Harmful use
0.999 0.001 0.000
Chapter XIV Diseases of the genitourinary system
0.999 0.001 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.999 0.001 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.999 0.001 0.000
Z72.0 Tobacco use
0.998 0.002 0.000
F60-F69 Disorders of adult personality and behaviour
0.997 0.003 0.000
S70-S79 Injuries to the hip and thigh
0.997 0.003 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.996 0.004 0.000
F60 Specific personality disorders
0.996 0.004 0.000
N18.9 Chronic renal failure, unspecified
0.994 0.006 0.000
N18.4 Chronic kidney disease, stage 4
0.993 0.007 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.992 0.008 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.990 0.010 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.988 0.012 0.000
M65-M68 Disorders of synovium and tendon
0.988 0.012 0.000
F60.3 Emotionally unstable personality disorder
0.987 0.013 0.000
T43.2 Other and unspecified antidepressants
0.986 0.014 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.986 0.014 0.000
M05-M14 Inflammatory polyarthropathies
0.983 0.017 0.000
T51 Toxic effect of alcohol
0.983 0.017 0.000
B95-B98 Bacterial, viral and other infectious agents
0.982 0.018 0.000
Chapter I Certain infectious and parasitic diseases
0.981 0.019 0.000
F30-F39 Mood [affective] disorders
0.981 0.019 0.000
Z72 Problems related to lifestyle
0.977 0.023 0.000
M65 Synovitis and tenosynovitis
0.976 0.024 0.000
S70 Superficial injury of hip and thigh
0.975 0.025 0.000
N25-N29 Other disorders of kidney and ureter
0.975 0.025 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.975 0.025 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.975 0.025 0.000
F10.0 Acute intoxication
0.974 0.026 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.974 0.026 0.000
M06 Other rheumatoid arthritis
0.973 0.027 0.000
F33 Recurrent depressive disorder
0.973 0.027 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.973 0.027 0.000
R20 Disturbances of skin sensation
0.971 0.029 0.000
S10-S19 Injuries to the neck
0.971 0.029 0.000
F60.9 Personality disorder, unspecified
0.969 0.031 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.969 0.031 0.000
M50-M54 Other dorsopathies
0.968 0.032 0.000
S72 Fracture of femur
0.966 0.034 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.966 0.034 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.964 0.036 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.964 0.036 0.000
W50-W64 Exposure to animate mechanical forces
0.964 0.036 0.000
R20.2 Paraesthesia of skin
0.963 0.037 0.000
N18.5 Chronic kidney disease, stage 5
0.963 0.037 0.000
M54 Dorsalgia
0.961 0.039 0.000
W20-W49 Exposure to inanimate mechanical forces
0.959 0.041 0.000
T51.9 Alcohol, unspecified
0.952 0.048 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.949 0.051 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.948 0.052 0.000
F10.2 Dependence syndrome
0.948 0.052 0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.947 0.053 0.000
S70.9 Superficial injury of hip and thigh, unspecified
0.945 0.055 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.944 0.056 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.940 0.060 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.938 0.062 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.935 0.065 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.933 0.067 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.932 0.068 0.000
N26 Unspecified contracted kidney
0.929 0.071 0.000
M06.0 Seronegative rheumatoid arthritis
0.929 0.071 0.000
R21 Rash and other nonspecific skin eruption
0.926 0.074 0.000
Chapter XXI Factors influencing health status and contact with health services
0.926 0.074 0.000
M54.5 Low back pain
0.924 0.076 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.923 0.077 0.000
M54.56 Low back pain (Lumbar region)
0.922 0.078 0.000
R85 Abnormal findings in specimens from digestive organs and abdominal cavity
0.922 0.078 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.922 0.078 0.000
M06.3 Rheumatoid nodule
0.921 0.079 0.000
T51.0 Ethanol
0.920 0.080 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.920 0.080 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.918 0.082 0.000
T18 Foreign body in alimentary tract
0.917 0.083 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.916 0.084 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.913 0.087 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.909 0.091 0.000
M54.4 Lumbago with sciatica
0.909 0.091 0.000
M54.9 Dorsalgia, unspecified
0.906 0.094 0.000
N25 Disorders resulting from impaired renal tubular function
0.903 0.097 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.900 0.100 0.000
W00-W19 Falls
0.895 0.105 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.892 0.108 0.000
W44 Foreign body entering into or through eye or natural orifice
0.891 0.109 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.891 0.109 0.000
M66 Spontaneous rupture of synovium and tendon
0.890 0.110 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.889 0.111 0.000
R85.5 Abnormal microbiological findings
0.889 0.111 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.888 0.112 0.000
F10.4 Withdrawal state with delirium
0.888 0.112 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.888 0.112 0.000
S71 Open wound of hip and thigh
0.886 0.114 0.000
T18.1 Foreign body in oesophagus
0.885 0.115 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.882 0.118 0.000
X50-X57 Overexertion, travel and privation
0.882 0.118 0.000
N18.8 Other chronic renal failure
0.881 0.119 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.881 0.119 0.000
F25 Schizoaffective disorders
0.879 0.121 0.000
M80-M85 Disorders of bone density and structure
0.876 0.124 0.000
M91-M94 Chondropathies
0.876 0.124 0.000
S72.4 Fracture of lower end of femur
0.875 0.125 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.875 0.125 0.000
F10.3 Withdrawal state
0.874 0.126 0.000
W50 Hit, struck, kicked, twisted, bitten or scratched by another person
0.874 0.126 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.873 0.127 0.000
W22 Striking against or struck by other objects
0.873 0.127 0.000
N19 Unspecified renal failure
0.873 0.127 0.000
Z75 Problems related to medical facilities and other health care
0.869 0.131 0.000
Q80-Q89 Other congenital malformations
0.867 0.133 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.866 0.134 0.000
Z71.1 Person with feared complaint in whom no diagnosis is made
0.864 0.136 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.863 0.137 0.000
A30-A49 Other bacterial diseases
0.861 0.139 0.000
S72.3 Fracture of shaft of femur
0.861 0.139 0.000
F32 Depressive episode
0.860 0.140 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.860 0.140 0.000
S11 Open wound of neck
0.857 0.143 0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)
0.856 0.144 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.851 0.149 0.000
T42.4 Benzodiazepines
0.851 0.149 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.850 0.150 0.000
W51 Striking against or bumped into by another person
0.848 0.152 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.847 0.153 0.000
T43.6 Psychostimulants with abuse potential
0.846 0.154 0.000
M94 Other disorders of cartilage
0.846 0.154 0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.845 0.155 0.000
T00-T07 Injuries involving multiple body regions
0.844 0.156 0.000
W44.0 Home
0.843 0.157 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.841 0.159 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.841 0.159 0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.840 0.160 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.836 0.164 0.000
X10-X19 Contact with heat and hot substances
0.834 0.166 0.000
M05 Seropositive rheumatoid arthritis
0.832 0.168 0.000
R85.7 Abnormal histological findings
0.831 0.169 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.830 0.170 0.000
S70.1 Contusion of thigh
0.829 0.171 0.000
M60-M63 Disorders of muscles
0.829 0.171 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.826 0.174 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.824 0.176 0.000
X00-X09 Exposure to smoke, fire and flames
0.823 0.177 0.000
Q00-Q07 Congenital malformations of the nervous system
0.821 0.179 0.000
W45 Foreign body or object entering through skin
0.821 0.179 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.821 0.179 0.000
M70-M79 Other soft tissue disorders
0.821 0.179 0.000
F17.3 Withdrawal state
0.819 0.181 0.000
N30-N39 Other diseases of urinary system
0.819 0.181 0.000
Y43 Primarily systemic agents
0.818 0.182 0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)
0.817 0.183 0.000
F25.1 Schizoaffective disorder, depressive type
0.817 0.183 0.000
F20 Schizophrenia
0.817 0.183 0.000
N39 Other disorders of urinary system
0.816 0.184 0.000
W57 Bitten or stung by non-venomous insect and other non-venomous arthropods
0.816 0.184 0.000
T85.2 Mechanical complication of intraocular lens
0.815 0.185 0.000
T46.1 Calcium-channel blockers
0.815 0.185 0.000
V40-V49 Car occupant injured in transport accident
0.815 0.185 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.815 0.185 0.000
B65-B83 Helminthiases
0.814 0.186 0.000
N25.8 Other disorders resulting from impaired renal tubular function
0.813 0.187 0.000
W10 Fall on and from stairs and steps
0.812 0.188 0.000
M86-M90 Other osteopathies
0.810 0.190 0.000
R41.3 Other amnesia
0.810 0.190 0.000
Y43.3 Other antineoplastic drugs
0.809 0.191 0.000
S72.2 Subtrochanteric fracture
0.809 0.191 0.000
Q60-Q64 Congenital malformations of the urinary system
0.808 0.192 0.000
S71.1 Open wound of thigh
0.807 0.193 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.806 0.194 0.000
N39.0 Urinary tract infection, site not specified
0.806 0.194 0.000
X60-X84 Intentional self-harm
0.804 0.195 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.802 0.198 0.000
M81 Osteoporosis without pathological fracture
0.802 0.198 0.000
X50 Overexertion and strenuous or repetitive movements
0.800 0.200 0.000
F32.9 Depressive episode, unspecified
0.798 0.202 0.000
M66.2 Spontaneous rupture of extensor tendons
0.797 0.203 0.000
N39.3 Stress incontinence
0.796 0.204 0.000
N27 Small kidney of unknown cause
0.796 0.204 0.000
F33.9 Recurrent depressive disorder, unspecified
0.795 0.205 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.794 0.206 0.000
Z75.5 Holiday relief care
0.794 0.206 0.000
F38 Other mood [affective] disorders
0.793 0.207 0.000
S10 Superficial injury of neck
0.792 0.208 0.000
R41.1 Anterograde amnesia
0.792 0.208 0.000
M94.8 Other specified disorders of cartilage
0.792 0.208 0.000
F60.6 Anxious [avoidant] personality disorder
0.791 0.209 0.000
T25 Burn and corrosion of ankle and foot
0.790 0.210 0.000
S72.40 Fracture of lower end of femur (closed)
0.789 0.211 0.000
V10-V19 Pedal cyclist injured in transport accident
0.788 0.212 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.788 0.212 0.000
V95-V97 Air and space transport accidents
0.786 0.214 0.000
S72.30 Fracture of shaft of femur (closed)
0.785 0.215 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.783 0.217 0.000
S72.0 Fracture of neck of femur
0.783 0.217 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.780 0.220 0.000
Z71.3 Dietary counselling and surveillance
0.779 0.221 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.779 0.221 0.000
T59 Toxic effect of other gases, fumes and vapours
0.778 0.222 0.000
T56 Toxic effect of metals
0.778 0.222 0.000
F33.0 Recurrent depressive disorder, current episode mild
0.776 0.224 0.000
Y00-Y09 Assault
0.775 0.225 0.000
Z71.6 Tobacco abuse counselling
0.775 0.225 0.000
W50.9 Unspecified place
0.774 0.226 0.000
W22.9 Unspecified place
0.774 0.226 0.000
M06.9 Rheumatoid arthritis, unspecified
0.773 0.227 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.773 0.227 0.000
X41.9 Unspecified place
0.772 0.228 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.772 0.228 0.000
N00-N08 Glomerular diseases
0.772 0.228 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.772 0.228 0.000
S19 Other and unspecified injuries of neck
0.770 0.230 0.000
M06.34 Rheumatoid nodule (Hand)
0.770 0.230 0.000
W11 Fall on and from ladder
0.769 0.231 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.769 0.231 0.000
T15 Foreign body on external eye
0.769 0.231 0.000
N60-N64 Disorders of breast
0.768 0.232 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.767 0.233 0.000
A20-A28 Certain zoonotic bacterial diseases
0.767 0.233 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.767 0.233 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.766 0.234 0.000
S70.8 Other superficial injuries of hip and thigh
0.765 0.235 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.764 0.236 0.000
M13 Other arthritis
0.764 0.236 0.000
R46 Symptoms and signs involving appearance and behaviour
0.763 0.237 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.763 0.237 0.000
X47 Accidental poisoning by and exposure to other gases and vapours
0.762 0.238 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.762 0.238 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.762 0.238 0.000
T66-T78 Other and unspecified effects of external causes
0.761 0.239 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.761 0.239 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.760 0.240 0.000
M94.88 Other specified disorders of cartilage (Other)
0.759 0.241 0.000
Q82 Other congenital malformations of skin
0.759 0.241 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.759 0.241 0.000
T62 Toxic effect of other noxious substances eaten as food
0.757 0.243 0.000
N25.9 Disorder resulting from impaired renal tubular function, unspecified
0.757 0.243 0.000
S11.9 Open wound of neck, part unspecified
0.755 0.245 0.000
F34 Persistent mood [affective] disorders
0.754 0.246 0.000
W49 Exposure to other and unspecified inanimate mechanical forces
0.752 0.247 0.000
W75-W84 Other accidental threats to breathing
0.751 0.249 0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.749 0.251 0.000
W10.4 Street and highway
0.749 0.251 0.000
M54.6 Pain in thoracic spine
0.749 0.251 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.748 0.252 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.747 0.253 0.000
Z71.4 Alcohol abuse counselling and surveillance
0.746 0.254 0.000
F20.9 Schizophrenia, unspecified
0.746 0.254 0.000
W24 Contact with lifting and transmission devices, not elsewhere classified
0.745 0.255 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.744 0.256 0.000
T42.0 Hydantoin derivatives
0.743 0.257 0.000
Q07 Other congenital malformations of nervous system
0.743 0.257 0.000
Z72.9 Problem related to lifestyle, unspecified
0.742 0.257 0.000
S14 Injury of nerves and spinal cord at neck level
0.742 0.258 0.000
A49 Bacterial infection of unspecified site
0.742 0.258 0.000
W51.9 Unspecified place
0.740 0.260 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.740 0.260 0.000
R89 Abnormal findings in specimens from other organs, systems and tissues
0.738 0.262 0.000
V70-V79 Bus occupant injured in transport accident
0.735 0.265 0.000
T50.4 Drugs affecting uric acid metabolism
0.734 0.266 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.734 0.266 0.000
R27 Other lack of coordination
0.734 0.266 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.733 0.267 0.000
Y52 Agents primarily affecting the cardiovascular system
0.733 0.267 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.732 0.268 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.732 0.268 0.000
X43 Accidental poisoning by and exposure to other drugs acting on the autonomic nervous system
0.732 0.268 0.000
F10.1 Harmful use
0.730 0.270 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.729 0.270 0.000
F99-F99 Unspecified mental disorder
0.729 0.271 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.729 0.271 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.729 0.271 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.728 0.272 0.000
M08 Juvenile arthritis
0.727 0.273 0.000
S72.8 Fractures of other parts of femur
0.726 0.274 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.726 0.274 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.726 0.274 0.000
F25.0 Schizoaffective disorder, manic type
0.726 0.274 0.000
M66.24 Spontaneous rupture of extensor tendons (Hand)
0.724 0.276 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.723 0.277 0.000
F10.9 Unspecified mental and behavioural disorder
0.723 0.277 0.000
Z72.1 Alcohol use
0.723 0.277 0.000
T65 Toxic effect of other and unspecified substances
0.720 0.280 0.000
A40 Streptococcal septicaemia
0.720 0.280 0.000
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand
0.720 0.280 0.000
T21 Burn and corrosion of trunk
0.720 0.280 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.719 0.281 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.719 0.281 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.717 0.283 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.717 0.283 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.717 0.283 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.717 0.283 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.717 0.283 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.717 0.283 0.000
Y10-Y34 Event of undetermined intent
0.717 0.283 0.000
X85-X99 Assault
0.717 0.283 0.000
X30-X39 Exposure to forces of nature
0.717 0.283 0.000
W65-W74 Accidental drowning and submersion
0.717 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.717 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.717 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.717 0.283 0.000
Chapter XXII Codes for special purposes
0.717 0.283 0.000
F17.9 Unspecified mental and behavioural disorder
0.716 0.283 0.000
F17.8 Other mental and behavioural disorders
0.716 0.283 0.000
F17.7 Residual and late-onset psychotic disorder
0.716 0.283 0.000
F17.6 Amnesic syndrome
0.716 0.283 0.000
F17.5 Psychotic disorder
0.716 0.283 0.000
F17.4 Withdrawal state with delirium
0.716 0.283 0.000
F17.0 Acute intoxication
0.716 0.283 0.000
W50.8 Other specified place
0.716 0.284 0.000
Q85 Phakomatoses, not elsewhere classified
0.716 0.284 0.000
Z75.1 Person awaiting admission to adequate facility elsewhere
0.716 0.284 0.000
T22.1 Burn of first degree of shoulder and upper limb, except wrist and hand
0.716 0.284 0.000
F10.8 Other mental and behavioural disorders
0.716 0.284 0.000
F10.7 Residual and late-onset psychotic disorder
0.716 0.284 0.000
F32.0 Mild depressive episode
0.716 0.284 0.000
T43.9 Psychotropic drug, unspecified
0.716 0.284 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.716 0.284 0.000
R86 Abnormal findings in specimens from male genital organs
0.716 0.284 0.000
V20-V29 Motorcycle rider injured in transport accident
0.716 0.284 0.000
F68 Other disorders of adult personality and behaviour
0.715 0.285 0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation
0.715 0.285 0.000
F65 Disorders of sexual preference
0.715 0.285 0.000
F63 Habit and impulse disorders
0.715 0.285 0.000
F62 Enduring personality changes, not attributable to brain damage and disease
0.715 0.285 0.000
F61 Mixed and other personality disorders
0.715 0.285 0.000
S78 Traumatic amputation of hip and thigh
0.715 0.285 0.000
S77 Crushing injury of hip and thigh
0.715 0.285 0.000
S75 Injury of blood vessels at hip and thigh level
0.715 0.285 0.000
S74 Injury of nerves at hip and thigh level
0.715 0.285 0.000
M14 Arthropathies in other diseases classified elsewhere
0.715 0.285 0.000
M87 Osteonecrosis
0.714 0.286 0.000
W15 Fall from cliff
0.714 0.286 0.000
F60.8 Other specific personality disorders
0.714 0.286 0.000
F60.4 Histrionic personality disorder
0.714 0.286 0.000
F60.2 Dissocial personality disorder
0.714 0.286 0.000
F60.1 Schizoid personality disorder
0.714 0.286 0.000
F60.0 Paranoid personality disorder
0.714 0.286 0.000
Z76 Persons encountering health services in other circumstances
0.713 0.287 0.000
V90-V94 Water transport accidents
0.712 0.288 0.000
X50.4 Street and highway
0.712 0.288 0.000
T23 Burn and corrosion of wrist and hand
0.712 0.288 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.711 0.289 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.711 0.289 0.000
T60 Toxic effect of pesticides
0.711 0.289 0.000
T57 Toxic effect of other inorganic substances
0.711 0.289 0.000
T54 Toxic effect of corrosive substances
0.711 0.289 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.711 0.289 0.000
T52 Toxic effect of organic solvents
0.711 0.289 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.711 0.289 0.000
T55 Toxic effect of soaps and detergents
0.711 0.289 0.000
T58 Toxic effect of carbon monoxide
0.711 0.289 0.000
F70-F79 Mental retardation
0.709 0.291 0.000
R20.1 Hypoaesthesia of skin
0.709 0.291 0.000
A31 Infection due to other mycobacteria
0.709 0.291 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.709 0.291 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.709 0.291 0.000
M66.3 Spontaneous rupture of flexor tendons
0.709 0.291 0.000
T86 Failure and rejection of transplanted organs and tissues
0.709 0.291 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.708 0.292 0.000
N18.0 End-stage renal disease
0.708 0.292 0.000
T18.5 Foreign body in anus and rectum
0.706 0.293 0.000
S13.6 Sprain and strain of joints and ligaments of other and unspecified parts of neck
0.706 0.294 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.705 0.295 0.000
W18 Other fall on same level
0.705 0.295 0.000
T51.8 Other alcohols
0.704 0.295 0.000
T51.3 Fusel oil
0.704 0.295 0.000
T51.2 2-Propanol
0.704 0.295 0.000
T51.1 Methanol
0.704 0.295 0.000
M70.6 Trochanteric bursitis
0.704 0.296 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.704 0.296 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.703 0.296 0.000
A75-A79 Rickettsioses
0.703 0.296 0.000
A70-A74 Other diseases caused by chlamydiae
0.703 0.296 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.703 0.297 0.000
T36 Poisoning by systemic antibiotics
0.703 0.297 0.000
N64 Other disorders of breast
0.701 0.299 0.000
Z72.6 Gambling and betting
0.701 0.299 0.000
Z72.5 High-risk sexual behaviour
0.701 0.299 0.000
Z72.4 Inappropriate diet and eating habits
0.701 0.299 0.000
Z72.3 Lack of physical exercise
0.701 0.299 0.000
M94.9 Disorder of cartilage, unspecified
0.700 0.300 0.000
M80 Osteoporosis with pathological fracture
0.700 0.300 0.000
M12 Other specific arthropathies
0.700 0.300 0.000
M65.2 Calcific tendinitis
0.700 0.300 0.000
M65.0 Abscess of tendon sheath
0.700 0.300 0.000
S70.7 Multiple superficial injuries of hip and thigh
0.699 0.301 0.000
Q35-Q37 Cleft lip and cleft palate
0.699 0.301 0.000
V98-V99 Other and unspecified transport accidents
0.699 0.301 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.699 0.301 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.699 0.301 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.699 0.301 0.000
T42.3 Barbiturates
0.699 0.301 0.000
T42.2 Succinimides and oxazolidinediones
0.699 0.301 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.698 0.302 0.000
M06.8 Other specified rheumatoid arthritis
0.698 0.302 0.000
M06.2 Rheumatoid bursitis
0.698 0.302 0.000
M06.1 Adult-onset Still's disease
0.698 0.302 0.000
F25.9 Schizoaffective disorder, unspecified
0.698 0.302 0.000
F33.8 Other recurrent depressive disorders
0.698 0.302 0.000
F33.4 Recurrent depressive disorder, currently in remission
0.698 0.302 0.000
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)
0.697 0.302 0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)
0.697 0.302 0.000
R83 Abnormal findings in cerebrospinal fluid
0.697 0.303 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.697 0.303 0.000
S00-S09 Injuries to the head
0.697 0.303 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.696 0.303 0.000
S17 Crushing injury of neck
0.696 0.304 0.000
S15 Injury of blood vessels at neck level
0.696 0.304 0.000
S18 Traumatic amputation at neck level
0.696 0.304 0.000
S16 Injury of muscle and tendon at neck level
0.696 0.304 0.000
F11 Mental and behavioural disorders due to use of opioids
0.696 0.304 0.000
M54.54 Low back pain-Thoracic
0.696 0.304 0.000
S13.4 Sprain and strain of cervical spine
0.696 0.304 0.000
S72.20 Subtrochanteric fracture (closed)
0.695 0.304 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.695 0.305 0.000
N10-N16 Renal tubulo-interstitial diseases
0.695 0.305 0.000
M54.1 Radiculopathy
0.695 0.305 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.694 0.305 0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere
0.694 0.306 0.000
X45 Accidental poisoning by and exposure to alcohol
0.694 0.306 0.000
F10.5 Psychotic disorder
0.694 0.306 0.000
X44 Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
0.693 0.306 0.000
R20.3 Hyperaesthesia
0.693 0.307 0.000
Q76 Congenital malformations of spine and bony thorax
0.693 0.307 0.000
S72.7 Multiple fractures of femur
0.693 0.307 0.000
N27.1 Small kidney, bilateral
0.693 0.307 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.693 0.307 0.000
F12.1 Harmful use
0.692 0.307 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.692 0.308 0.000
W45.8 Other specified place
0.692 0.308 0.000
R20.0 Anaesthesia of skin
0.692 0.308 0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified
0.692 0.308 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.691 0.309 0.000
T50.7 Analeptics and opioid receptor antagonists
0.691 0.309 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.691 0.309 0.000
T50.5 Appetite depressants
0.691 0.309 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.691 0.309 0.000
T50.1 Loop [high-ceiling] diuretics
0.691 0.309 0.000
T50.0 Mineralocorticoids and their antagonists
0.691 0.309 0.000
N17 Acute renal failure
0.691 0.309 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.691 0.309 0.000
W64 Exposure to other and unspecified animate mechanical forces
0.691 0.309 0.000
W59 Bitten or crushed by other reptiles
0.691 0.309 0.000
W58 Bitten or struck by crocodile or alligator
0.691 0.309 0.000
W56 Contact with marine animal
0.691 0.309 0.000
W54 Bitten or struck by dog
0.691 0.309 0.000
W53 Bitten by rat
0.691 0.309 0.000
W52 Crushed, pushed and stepped on by crowd or human stampede
0.691 0.309 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.691 0.309 0.000
X10 Contact with hot drinks, food, fats and cooking oils
0.691 0.309 0.000
W23 Caught, crushed, jammed or pinched in or between objects
0.690 0.310 0.000
T79-T79 Certain early complications of trauma
0.690 0.310 0.000
M54.0 Panniculitis affecting regions of neck and back
0.689 0.311 0.000
W19 Unspecified fall
0.689 0.311 0.000
M54.8 Other dorsalgia
0.688 0.312 0.000
Q66 Congenital deformities of feet
0.688 0.312 0.000
M81.2 Osteoporosis of disuse
0.687 0.313 0.000
W46 Contact with hypodermic needle
0.687 0.313 0.000
W43 Exposure to vibration
0.687 0.313 0.000
W42 Exposure to noise
0.687 0.313 0.000
W41 Exposure to high-pressure jet
0.687 0.313 0.000
W40 Explosion of other materials
0.687 0.313 0.000
W39 Discharge of firework
0.687 0.313 0.000
W38 Explosion and rupture of other specified pressurised devices
0.687 0.313 0.000
W37 Explosion and rupture of pressurised tyre, pipe or hose
0.687 0.313 0.000
W36 Explosion and rupture of gas cylinder
0.687 0.313 0.000
W35 Explosion and rupture of boiler
0.687 0.313 0.000
W34 Discharge from other and unspecified firearms
0.687 0.313 0.000
W33 Rifle, shotgun and larger firearm discharge
0.687 0.313 0.000
W32 Handgun discharge
0.687 0.313 0.000
W31 Contact with other and unspecified machinery
0.687 0.313 0.000
W30 Contact with agricultural machinery
0.687 0.313 0.000
W26 Contact with knife, sword or dagger
0.687 0.313 0.000
Q07.0 Arnold-Chiari syndrome
0.687 0.313 0.000
B99-B99 Other infectious diseases
0.687 0.313 0.000
T16 Foreign body in ear
0.686 0.314 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.686 0.314 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.685 0.315 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.685 0.315 0.000
F20.5 Residual schizophrenia
0.685 0.315 0.000
S72.41 Fracture of lower end of femur (open)
0.684 0.316 0.000
T50.8 Diagnostic agents
0.683 0.316 0.000
M79.6 Pain in limb
0.682 0.318 0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system
0.682 0.318 0.000
S00 Superficial injury of head
0.681 0.319 0.000
T87 Complications peculiar to reattachment and amputation
0.681 0.319 0.000
T18.9 Foreign body in alimentary tract, part unspecified
0.681 0.319 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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