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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs114122048
log Bayes Factor = 17.5378
Chromosome 5   position 167,787,265  (GRCh37) Explore rs114122048 on Ensembl!
Variant rs114122048 is part of Cluster X0210

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
E70-E90 Metabolic disorders
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
1.000 0.000 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.999 0.001 0.000
Y43 Primarily systemic agents
0.999 0.001 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.998 0.002 0.000
Y43.3 Other antineoplastic drugs
0.998 0.002 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.997 0.003 0.000
Chapter II Neoplasms
0.995 0.005 0.000
B95-B98 Bacterial, viral and other infectious agents
0.993 0.007 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.990 0.010 0.000
Chapter VII Diseases of the eye and adnexa
0.987 0.013 0.000
E86 Volume depletion
0.984 0.016 0.000
Chapter XIV Diseases of the genitourinary system
0.984 0.016 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.983 0.017 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.977 0.023 0.000
E10-E14 Diabetes mellitus
0.977 0.023 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.972 0.028 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.972 0.028 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.971 0.029 0.000
E87.7 Fluid overload
0.965 0.035 0.000
H04 Disorders of lachrymal system
0.964 0.036 0.000
D60-D64 Aplastic and other anaemias
0.964 0.036 0.000
N17-N19 Renal failure
0.964 0.036 0.000
A30-A49 Other bacterial diseases
0.963 0.037 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.959 0.041 0.000
E11 Non-insulin-dependent diabetes mellitus
0.953 0.047 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.945 0.055 0.000
Chapter VI Diseases of the nervous system
0.937 0.063 0.000
D70 Agranulocytosis
0.934 0.066 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.931 0.069 0.000
D64 Other anaemias
0.930 0.070 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.922 0.078 0.000
A41 Other septicaemia
0.922 0.078 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.921 0.079 0.000
E87.2 Acidosis
0.918 0.082 0.000
S40-S49 Injuries to the shoulder and upper arm
0.916 0.084 0.000
N10-N16 Renal tubulo-interstitial diseases
0.916 0.084 0.000
N18 Chronic renal failure
0.914 0.086 0.000
Chapter X Diseases of the respiratory system
0.909 0.091 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.908 0.092 0.000
M45-M49 Spondylopathies
0.906 0.094 0.000
D64.9 Anaemia, unspecified
0.905 0.095 0.000
B35-B49 Mycoses
0.904 0.096 0.000
E87.5 Hyperkalaemia
0.898 0.102 0.000
W20-W49 Exposure to inanimate mechanical forces
0.898 0.102 0.000
N00-N08 Glomerular diseases
0.897 0.103 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.895 0.105 0.000
E10 Insulin-dependent diabetes mellitus
0.894 0.106 0.000
M47 Spondylosis
0.892 0.108 0.000
N18.3 Chronic kidney disease, stage 3
0.891 0.109 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.890 0.110 0.000
S70-S79 Injuries to the hip and thigh
0.887 0.113 0.000
C91 Lymphoid leukaemia
0.883 0.117 0.000
E11.3 With ophthalmic complications
0.882 0.118 0.000
E11.2 With renal complications
0.882 0.118 0.000
B15-B19 Viral hepatitis
0.880 0.120 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.879 0.121 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.878 0.122 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.874 0.126 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.873 0.127 0.000
N13 Obstructive and reflux uropathy
0.872 0.128 0.000
J30-J39 Other diseases of upper respiratory tract
0.870 0.130 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.870 0.130 0.000
H04.9 Disorder of lachrymal system, unspecified
0.867 0.133 0.000
E16 Other disorders of pancreatic internal secretion
0.866 0.134 0.000
M70-M79 Other soft tissue disorders
0.865 0.135 0.000
A41.9 Septicaemia, unspecified
0.865 0.135 0.000
J00-J06 Acute upper respiratory infections
0.860 0.140 0.000
M05-M14 Inflammatory polyarthropathies
0.859 0.141 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.857 0.143 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.855 0.145 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.855 0.145 0.000
C64-C68 Malignant neoplasms of urinary tract
0.854 0.146 0.000
S20-S29 Injuries to the thorax
0.848 0.152 0.000
Chapter XXII Codes for special purposes
0.847 0.153 0.000
D45 Polycythaemia vera
0.847 0.153 0.000
W00-W19 Falls
0.845 0.155 0.000
X60-X84 Intentional self-harm
0.842 0.158 0.000
M47.9 Spondylosis, unspecified
0.841 0.159 0.000
S80-S89 Injuries to the knee and lower leg
0.838 0.162 0.000
H18 Other disorders of cornea
0.837 0.163 0.000
S10-S19 Injuries to the neck
0.836 0.164 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.836 0.164 0.000
H02 Other disorders of eyelid
0.836 0.164 0.000
D61 Other aplastic anaemias
0.833 0.167 0.000
D50-D53 Nutritional anaemias
0.832 0.168 0.000
B37 Candidiasis
0.831 0.169 0.000
G57 Mononeuropathies of lower limb
0.829 0.171 0.000
D73 Diseases of spleen
0.829 0.171 0.000
E16.2 Hypoglycaemia, unspecified
0.827 0.173 0.000
Y43.4 Immunosuppressive agents
0.825 0.175 0.000
J34 Other disorders of nose and nasal sinuses
0.825 0.175 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.824 0.176 0.000
E20-E35 Disorders of other endocrine glands
0.819 0.181 0.000
M86-M90 Other osteopathies
0.818 0.182 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.818 0.182 0.000
N19 Unspecified renal failure
0.817 0.183 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.817 0.183 0.000
H04.2 Epiphora
0.817 0.183 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.816 0.184 0.000
N17 Acute renal failure
0.814 0.186 0.000
N13.4 Hydroureter
0.813 0.187 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.812 0.188 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.812 0.188 0.000
H05 Disorders of orbit
0.811 0.189 0.000
E11.5 With peripheral circulatory complications
0.810 0.190 0.000
Y00-Y09 Assault
0.810 0.190 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.809 0.191 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.808 0.192 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.808 0.192 0.000
S40 Superficial injury of shoulder and upper arm
0.807 0.193 0.000
D46 Myelodysplastic syndromes
0.806 0.194 0.000
G90-G99 Other disorders of the nervous system
0.805 0.195 0.000
J34.2 Deviated nasal septum
0.803 0.197 0.000
M47.8 Other spondylosis
0.801 0.199 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.800 0.200 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.799 0.201 0.000
C92 Myeloid leukaemia
0.799 0.201 0.000
G82 Paraplegia and tetraplegia
0.798 0.202 0.000
N25-N29 Other disorders of kidney and ureter
0.794 0.206 0.000
H21 Other disorders of iris and ciliary body
0.793 0.207 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.793 0.207 0.000
H04.4 Chronic inflammation of lachrymal passages
0.789 0.211 0.000
B50-B64 Protozoal diseases
0.789 0.211 0.000
H04.3 Acute and unspecified inflammation of lachrymal passages
0.789 0.211 0.000
D48.1 Connective and other soft tissue
0.788 0.212 0.000
Y52 Agents primarily affecting the cardiovascular system
0.788 0.212 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.787 0.213 0.000
S81 Open wound of lower leg
0.787 0.213 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.785 0.215 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.785 0.215 0.000
V40-V49 Car occupant injured in transport accident
0.782 0.218 0.000
E80.4 Gilbert's syndrome
0.782 0.218 0.000
E65-E68 Obesity and other hyperalimentation
0.781 0.218 0.000
A40 Streptococcal septicaemia
0.781 0.219 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.779 0.220 0.000
S72 Fracture of femur
0.778 0.222 0.000
M06 Other rheumatoid arthritis
0.777 0.223 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.777 0.223 0.000
C81 Hodgkin's disease
0.776 0.224 0.000
T90 Sequelae of injuries of head
0.772 0.228 0.000
G57.6 Lesion of plantar nerve
0.771 0.229 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.767 0.233 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.767 0.233 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.767 0.233 0.000
D80-D89 Certain disorders involving the immune mechanism
0.766 0.234 0.000
Y42.7 Androgens and anabolic congeners
0.766 0.234 0.000
B18 Chronic viral hepatitis
0.766 0.234 0.000
N13.3 Other and unspecified hydronephrosis
0.765 0.235 0.000
H10-H13 Disorders of conjunctiva
0.765 0.235 0.000
H53-H54 Visual disturbances and blindness
0.764 0.235 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.761 0.239 0.000
J02 Acute pharyngitis
0.760 0.240 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.760 0.240 0.000
X20-X29 Contact with venomous animals and plants
0.759 0.241 0.000
C90.0 Multiple myeloma
0.759 0.241 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.758 0.242 0.000
J35 Chronic diseases of tonsils and adenoids
0.757 0.243 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.756 0.244 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.756 0.244 0.000
D48.5 Skin
0.756 0.244 0.000
E10.6 With other specified complications
0.754 0.245 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.753 0.247 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.752 0.247 0.000
H16 Keratitis
0.752 0.248 0.000
D75 Other diseases of blood and blood-forming organs
0.751 0.249 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.751 0.249 0.000
J00 Acute nasopharyngitis [common cold]
0.749 0.251 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.747 0.253 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.747 0.253 0.000
H04.1 Other disorders of lachrymal gland
0.747 0.253 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.747 0.253 0.000
T91 Sequelae of injuries of neck and trunk
0.746 0.253 0.000
T93 Sequelae of injuries of lower limb
0.746 0.254 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.745 0.255 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.744 0.256 0.000
Y42.5 Other oestrogens and progestogens
0.744 0.256 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.743 0.256 0.000
H02.0 Entropion and trichiasis of eyelid
0.743 0.257 0.000
E10.4 With neurological complications
0.741 0.259 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.741 0.259 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.740 0.259 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.740 0.260 0.000
C85.1 B-cell lymphoma, unspecified
0.739 0.261 0.000
D61.9 Aplastic anaemia, unspecified
0.739 0.261 0.000
E88 Other metabolic disorders
0.738 0.262 0.000
X50-X57 Overexertion, travel and privation
0.738 0.262 0.000
W21 Striking against or struck by sports equipment
0.738 0.262 0.000
D55-D59 Haemolytic anaemias
0.736 0.264 0.000
D69 Purpura and other haemorrhagic conditions
0.736 0.264 0.000
C83.0 Small cell (diffuse)
0.735 0.265 0.000
B25-B34 Other viral diseases
0.735 0.265 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.735 0.265 0.000
A49 Bacterial infection of unspecified site
0.735 0.265 0.000
B65-B83 Helminthiases
0.735 0.265 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.734 0.266 0.000
H17 Corneal scars and opacities
0.734 0.266 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.734 0.266 0.000
J36 Peritonsillar abscess
0.734 0.266 0.000
C67 Malignant neoplasm of bladder
0.733 0.267 0.000
N20-N23 Urolithiasis
0.733 0.267 0.000
C91.1 Chronic lymphocytic leukaemia
0.733 0.267 0.000
N02 Recurrent and persistent haematuria
0.732 0.268 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.731 0.269 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.731 0.269 0.000
W25 Contact with sharp glass
0.731 0.269 0.000
G82.2 Paraplegia, unspecified
0.729 0.271 0.000
H18.8 Other specified disorders of cornea
0.729 0.271 0.000
D51 Vitamin B12 deficiency anaemia
0.728 0.272 0.000
D68 Other coagulation defects
0.727 0.273 0.000
N10 Acute tubulo-interstitial nephritis
0.727 0.273 0.000
D73.0 Hyposplenism
0.726 0.274 0.000
S20 Superficial injury of thorax
0.725 0.275 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.725 0.275 0.000
Y57 Other and unspecified drugs and medicaments
0.724 0.276 0.000
E87.3 Alkalosis
0.723 0.277 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.723 0.277 0.000
C83.3 Large cell (diffuse)
0.723 0.277 0.000
Y40 Systemic antibiotics
0.722 0.278 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.720 0.280 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.720 0.280 0.000
N99-N99 Other disorders of the genitourinary system
0.719 0.281 0.000
N60-N64 Disorders of breast
0.718 0.282 0.000
C91.0 Acute lymphoblastic leukaemia
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.717 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.717 0.283 0.000
Y10-Y34 Event of undetermined intent
0.717 0.283 0.000
X85-X99 Assault
0.717 0.283 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.717 0.283 0.000
X30-X39 Exposure to forces of nature
0.717 0.283 0.000
X10-X19 Contact with heat and hot substances
0.717 0.283 0.000
X00-X09 Exposure to smoke, fire and flames
0.717 0.283 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.717 0.283 0.000
W75-W84 Other accidental threats to breathing
0.717 0.283 0.000
W65-W74 Accidental drowning and submersion
0.717 0.283 0.000
W50-W64 Exposure to animate mechanical forces
0.717 0.283 0.000
V98-V99 Other and unspecified transport accidents
0.717 0.283 0.000
V95-V97 Air and space transport accidents
0.717 0.283 0.000
V90-V94 Water transport accidents
0.717 0.283 0.000
V80-V89 Other land transport accidents
0.717 0.283 0.000
V70-V79 Bus occupant injured in transport accident
0.717 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.717 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.717 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.717 0.283 0.000
V01-V09 Pedestrian injured in transport accident
0.717 0.283 0.000
E10.9 Without complications
0.717 0.283 0.000
E85 Amyloidosis
0.717 0.283 0.000
E84 Cystic fibrosis
0.717 0.283 0.000
E79 Disorders of purine and pyrimidine metabolism
0.717 0.283 0.000
E77 Disorders of glycoprotein metabolism
0.717 0.283 0.000
E76 Disorders of glycosaminoglycan metabolism
0.717 0.283 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.717 0.283 0.000
E74 Other disorders of carbohydrate metabolism
0.717 0.283 0.000
E73 Lactose intolerance
0.717 0.283 0.000
E72 Other disorders of amino-acid metabolism
0.717 0.283 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.717 0.283 0.000
E70 Disorders of aromatic amino-acid metabolism
0.717 0.283 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.717 0.283 0.000
B99-B99 Other infectious diseases
0.717 0.283 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.717 0.283 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.717 0.283 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.717 0.283 0.000
A80-A89 Viral infections of the central nervous system
0.717 0.283 0.000
A75-A79 Rickettsioses
0.717 0.283 0.000
A70-A74 Other diseases caused by chlamydiae
0.717 0.283 0.000
A65-A69 Other spirochaetal diseases
0.717 0.283 0.000
A20-A28 Certain zoonotic bacterial diseases
0.717 0.283 0.000
A15-A19 Tuberculosis
0.717 0.283 0.000
Y59 Other and unspecified vaccines and biological substances
0.717 0.283 0.000
Y58 Bacterial vaccines
0.717 0.283 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.717 0.283 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.717 0.283 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.717 0.283 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.717 0.283 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.717 0.283 0.000
Y48 Anaesthetics and therapeutic gases
0.717 0.283 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.717 0.283 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.717 0.283 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.717 0.283 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.717 0.283 0.000
Y43.9 Primarily systemic agent, unspecified
0.716 0.284 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.716 0.284 0.000
Y43.6 Enzymes, not elsewhere classified
0.716 0.284 0.000
Y43.5 Acidifying and alkalising agents
0.716 0.284 0.000
Y43.2 Antineoplastic natural products
0.716 0.284 0.000
Y43.1 Antineoplastic antimetabolites
0.716 0.284 0.000
Y43.0 Antiallergic and antiemetic drugs
0.716 0.284 0.000
M47.2 Other spondylosis with radiculopathy
0.715 0.285 0.000
E87.4 Mixed disorder of acid-base balance
0.715 0.285 0.000
T33-T35 Frostbite
0.715 0.285 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.715 0.285 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.715 0.285 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.715 0.285 0.000
T00-T07 Injuries involving multiple body regions
0.715 0.285 0.000
M60-M63 Disorders of muscles
0.714 0.286 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.714 0.286 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.714 0.286 0.000
M20-M25 Other joint disorders
0.714 0.286 0.000
H20 Iridocyclitis
0.713 0.287 0.000
H02.8 Other specified disorders of eyelid
0.713 0.287 0.000
W44 Foreign body entering into or through eye or natural orifice
0.713 0.287 0.000
M72 Fibroblastic disorders
0.712 0.288 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.711 0.288 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.711 0.289 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.710 0.290 0.000
C95 Leukaemia of unspecified cell type
0.710 0.290 0.000
C94 Other leukaemias of specified cell type
0.710 0.290 0.000
C93 Monocytic leukaemia
0.710 0.290 0.000
C88 Malignant immunoproliferative diseases
0.710 0.290 0.000
C86 Other specified types of T/NK-cell lymphoma
0.710 0.290 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.710 0.290 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.710 0.290 0.000
N17.9 Acute renal failure, unspecified
0.707 0.293 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.706 0.294 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.705 0.294 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.705 0.295 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.705 0.295 0.000
Y44 Agents primarily affecting blood constituents
0.703 0.296 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.701 0.299 0.000
E12 Malnutrition-related diabetes mellitus
0.700 0.300 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.700 0.300 0.000
S70 Superficial injury of hip and thigh
0.699 0.301 0.000
H43-H45 Disorders of vitreous body and globe
0.699 0.301 0.000
W22 Striking against or struck by other objects
0.698 0.301 0.000
M71 Other bursopathies
0.698 0.302 0.000
D00-D09 In situ neoplasms
0.698 0.302 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.697 0.303 0.000
D74 Methaemoglobinaemia
0.697 0.303 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.697 0.303 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.697 0.303 0.000
T92 Sequelae of injuries of upper limb
0.697 0.303 0.000
H05.2 Exophthalmic conditions
0.697 0.303 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.696 0.304 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.696 0.304 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.696 0.304 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.696 0.304 0.000
S71 Open wound of hip and thigh
0.696 0.304 0.000
T98 Sequelae of other and unspecified effects of external causes
0.695 0.305 0.000
B15 Acute hepatitis A
0.694 0.306 0.000
M10 Gout
0.692 0.307 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.692 0.308 0.000
T17 Foreign body in respiratory tract
0.692 0.308 0.000
N76 Other inflammation of vagina and vulva
0.692 0.308 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.692 0.308 0.000
H04.8 Other disorders of lachrymal system
0.691 0.309 0.000
H04.6 Other changes in lachrymal passages
0.691 0.309 0.000
H04.0 Dacryoadenitis
0.691 0.309 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.691 0.309 0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis
0.691 0.309 0.000
S46.0 Injury of tendon of the rotator cuff of shoulder
0.691 0.309 0.000
A48 Other bacterial diseases, not elsewhere classified
0.690 0.309 0.000
A44 Bartonellosis
0.690 0.309 0.000
A43 Nocardiosis
0.690 0.309 0.000
A42 Actinomycosis
0.690 0.309 0.000
A39 Meningococcal infection
0.690 0.309 0.000
A37 Whooping cough
0.690 0.309 0.000
A36 Diphtheria
0.690 0.309 0.000
A32 Listeriosis
0.690 0.309 0.000
A31 Infection due to other mycobacteria
0.690 0.309 0.000
A30 Leprosy [Hansen's disease]
0.690 0.309 0.000
A38 Scarlet fever
0.690 0.309 0.000
A35 Other tetanus
0.690 0.309 0.000
A34 Obstetrical tetanus
0.690 0.309 0.000
A33 Tetanus neonatorum
0.690 0.309 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.690 0.310 0.000
C91.4 Hairy-cell leukaemia
0.690 0.310 0.000
T79-T79 Certain early complications of trauma
0.690 0.310 0.000
E11.4 With neurological complications
0.690 0.310 0.000
J02.9 Acute pharyngitis, unspecified
0.689 0.311 0.000
C73 Malignant neoplasm of thyroid gland
0.689 0.311 0.000
H18.2 Other corneal oedema
0.689 0.311 0.000
B37.2 Candidiasis of skin and nail
0.688 0.312 0.000
D46.9 Myelodysplastic syndrome, unspecified
0.688 0.312 0.000
G58 Other mononeuropathies
0.688 0.312 0.000
M14 Arthropathies in other diseases classified elsewhere
0.688 0.312 0.000
M00-M03 Infectious arthropathies
0.688 0.312 0.000
X68 Intentional self-poisoning by and exposure to pesticides
0.687 0.313 0.000
S11 Open wound of neck
0.687 0.313 0.000
N03 Chronic nephritic syndrome
0.685 0.315 0.000
M91-M94 Chondropathies
0.684 0.316 0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified
0.684 0.316 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.684 0.316 0.000
E11.8 With unspecified complications
0.683 0.317 0.000
E11.7 With multiple complications
0.683 0.317 0.000
E11.6 With other specified complications
0.683 0.317 0.000
E11.1 With ketoacidosis
0.683 0.317 0.000
E11.0 With coma
0.683 0.317 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.683 0.317 0.000
H02.6 Xanthelasma of eyelid
0.683 0.317 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.683 0.317 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.683 0.317 0.000
E13 Other specified diabetes mellitus
0.682 0.318 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.682 0.318 0.000
S90-S99 Injuries to the ankle and foot
0.681 0.319 0.000
M47.1 Other spondylosis with myelopathy
0.681 0.319 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.681 0.319 0.000
N72 Inflammatory disease of cervix uteri
0.681 0.319 0.000
V20-V29 Motorcycle rider injured in transport accident
0.680 0.320 0.000
G57.3 Lesion of lateral popliteal nerve
0.679 0.320 0.000
N18.4 Chronic kidney disease, stage 4
0.679 0.321 0.000
S80 Superficial injury of lower leg
0.679 0.321 0.000
N18.2 Chronic kidney disease, stage 2
0.678 0.321 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.678 0.322 0.000
M89 Other disorders of bone
0.678 0.322 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.677 0.323 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.677 0.323 0.000
H15 Disorders of sclera
0.677 0.323 0.000
Y86 Sequelae of other accidents
0.677 0.323 0.000
E10.2 With renal complications
0.677 0.323 0.000
M80-M85 Disorders of bone density and structure
0.676 0.324 0.000
J09-J18 Influenza and pneumonia
0.676 0.324 0.000
N20 Calculus of kidney and ureter
0.676 0.324 0.000
E50-E64 Other nutritional deficiencies
0.676 0.324 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.676 0.324 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.676 0.324 0.000
B37.3 Candidiasis of vulva and vagina
0.675 0.325 0.000
H02.1 Ectropion of eyelid
0.674 0.326 0.000
C92.0 Acute myeloid leukaemia
0.674 0.326 0.000
Y04 Assault by bodily force
0.674 0.326 0.000
T66-T78 Other and unspecified effects of external causes
0.673 0.326 0.000
X78 Intentional self-harm by sharp object
0.673 0.327 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.672 0.328 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.671 0.329 0.000
C50-C50 Malignant neoplasm of breast
0.671 0.329 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.670 0.330 0.000
S81.9 Open wound of lower leg, part unspecified
0.668 0.332 0.000
S81.0 Open wound of knee
0.668 0.332 0.000
T95 Sequelae of burns, corrosions and frostbite
0.668 0.332 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.668 0.332 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.668 0.332 0.000
J60-J70 Lung diseases due to external agents
0.667 0.333 0.000
J35.1 Hypertrophy of tonsils
0.667 0.333 0.000
D64.8 Other specified anaemias
0.667 0.333 0.000
D64.4 Congenital dyserythropoietic anaemia
0.667 0.333 0.000
D64.3 Other sideroblastic anaemias
0.667 0.333 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.667 0.333 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.667 0.333 0.000
D64.0 Hereditary sideroblastic anaemia
0.667 0.333 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.666 0.334 0.000
G70-G73 Diseases of myoneural junction and muscle
0.666 0.334 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.664 0.336 0.000
B37.8 Candidiasis of other sites
0.664 0.336 0.000
N60 Benign mammary dysplasia
0.664 0.336 0.000
Y88 Sequelae of surgical and medical care as external cause
0.663 0.337 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.662 0.338 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.662 0.338 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.662 0.338 0.000
E15 Nondiabetic hypoglycaemic coma
0.661 0.339 0.000
S81.8 Open wound of other parts of lower leg
0.661 0.339 0.000
A41.4 Septicaemia due to anaerobes
0.661 0.339 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.661 0.339 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.661 0.339 0.000
B35 Dermatophytosis
0.661 0.339 0.000
S40.8 Other superficial injuries of shoulder and upper arm
0.661 0.339 0.000
S72.2 Subtrochanteric fracture
0.659 0.340 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.659 0.341 0.000
H21.0 Hyphaema
0.659 0.341 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.658 0.341 0.000
C45 Mesothelioma
0.658 0.342 0.000
W07 Fall involving chair
0.658 0.342 0.000
J04 Acute laryngitis and tracheitis
0.657 0.342 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.657 0.343 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.657 0.343 0.000
S48 Traumatic amputation of shoulder and upper arm
0.657 0.343 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.657 0.343 0.000
S44 Injury of nerves at shoulder and upper arm level
0.657 0.343 0.000
S41 Open wound of shoulder and upper arm
0.657 0.343 0.000
S47 Crushing injury of shoulder and upper arm
0.657 0.343 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.656 0.343 0.000
N15 Other renal tubulo-interstitial diseases
0.656 0.343 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.656 0.343 0.000
N11 Chronic tubulo-interstitial nephritis
0.656 0.343 0.000
H54 Blindness and low vision
0.656 0.344 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.656 0.344 0.000
M06.0 Seronegative rheumatoid arthritis
0.656 0.344 0.000
N18.8 Other chronic renal failure
0.655 0.344 0.000
N18.1 Chronic kidney disease, stage 1
0.655 0.344 0.000
E40-E46 Malnutrition
0.655 0.345 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.655 0.345 0.000
M05 Seropositive rheumatoid arthritis
0.654 0.346 0.000
J37 Chronic laryngitis and laryngotracheitis
0.654 0.346 0.000
A46 Erysipelas
0.653 0.347 0.000
M40-M43 Deforming dorsopathies
0.653 0.347 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.652 0.348 0.000
Y42.9 Other and unspecified hormone antagonists
0.651 0.349 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.651 0.349 0.000
Y42.4 Oral contraceptives
0.651 0.349 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.651 0.349 0.000
Y42.2 Antithyroid drugs
0.651 0.349 0.000
Y42.1 Thyroid hormones and substitutes
0.651 0.349 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.651 0.349 0.000
G95 Other diseases of spinal cord
0.651 0.349 0.000
A40.0 Septicaemia due to streptococcus, group A
0.651 0.349 0.000
H55-H59 Other disorders of eye and adnexa
0.650 0.349 0.000
M49 Spondylopathies in diseases classified elsewhere
0.650 0.350 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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