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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2250422
log Bayes Factor = 11.7971
Chromosome 17   position 48,351,018  (GRCh37) Explore rs2250422 on Ensembl!
Variant rs2250422 is part of Cluster X0133

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
M05-M14 Inflammatory polyarthropathies
1.000 0.000 0.000
A30-A49 Other bacterial diseases
0.999 0.001 0.000
M06 Other rheumatoid arthritis
0.999 0.001 0.000
Chapter XX External causes of morbidity and mortality
0.999 0.001 0.000
M06.9 Rheumatoid arthritis, unspecified
0.997 0.003 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.997 0.003 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.997 0.003 0.000
Chapter V Mental and behavioural disorders
0.995 0.005 0.000
F30-F39 Mood [affective] disorders
0.995 0.005 0.000
A41 Other septicaemia
0.993 0.007 0.000
F31 Bipolar affective disorder
0.990 0.010 0.000
Chapter X Diseases of the respiratory system
0.988 0.012 0.000
O60-O75 Complications of labour and delivery
0.988 0.012 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.986 0.014 0.000
M45-M49 Spondylopathies
0.976 0.024 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.976 0.024 0.000
F32 Depressive episode
0.964 0.036 0.000
S00-S09 Injuries to the head
0.963 0.037 0.000
O63 Long labour
0.961 0.039 0.000
A41.9 Septicaemia, unspecified
0.961 0.039 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.958 0.042 0.000
A49 Bacterial infection of unspecified site
0.951 0.049 0.000
S09 Other and unspecified injuries of head
0.941 0.059 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.941 0.059 0.000
F32.1 Moderate depressive episode
0.940 0.060 0.000
O63.1 Prolonged second stage (of labour)
0.932 0.068 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.932 0.068 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.930 0.070 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.929 0.071 0.000
M45 Ankylosing spondylitis
0.928 0.072 0.000
S09.9 Unspecified injury of head
0.927 0.073 0.000
Chapter II Neoplasms
0.925 0.075 0.000
C15-C26 Malignant neoplasms of digestive organs
0.923 0.077 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.920 0.080 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.918 0.082 0.000
B25-B34 Other viral diseases
0.914 0.086 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.914 0.086 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.908 0.092 0.000
J40-J47 Chronic lower respiratory diseases
0.906 0.094 0.000
T90 Sequelae of injuries of head
0.905 0.095 0.000
C18 Malignant neoplasm of colon
0.905 0.095 0.000
C18.9 Colon, unspecified
0.899 0.101 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.897 0.103 0.000
M10 Gout
0.896 0.104 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.896 0.104 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.894 0.106 0.000
W00-W19 Falls
0.894 0.106 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.891 0.109 0.000
Y43 Primarily systemic agents
0.889 0.111 0.000
F31.9 Bipolar affective disorder, unspecified
0.880 0.120 0.000
T79-T79 Certain early complications of trauma
0.880 0.120 0.000
M40-M43 Deforming dorsopathies
0.879 0.121 0.000
O42 Premature rupture of membranes
0.877 0.123 0.000
M05 Seropositive rheumatoid arthritis
0.876 0.124 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.875 0.125 0.000
J09-J18 Influenza and pneumonia
0.871 0.129 0.000
M06.3 Rheumatoid nodule
0.871 0.129 0.000
J60-J70 Lung diseases due to external agents
0.870 0.130 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.866 0.134 0.000
M48 Other spondylopathies
0.863 0.137 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.861 0.139 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.861 0.139 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.852 0.148 0.000
T90.2 Sequelae of fracture of skull and facial bones
0.851 0.149 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.850 0.150 0.000
Chapter XXII Codes for special purposes
0.849 0.151 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.846 0.154 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.846 0.154 0.000
Y52 Agents primarily affecting the cardiovascular system
0.845 0.155 0.000
Y44 Agents primarily affecting blood constituents
0.844 0.156 0.000
A41.8 Other specified septicaemia
0.842 0.158 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.838 0.162 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.835 0.165 0.000
A49.8 Other bacterial infections of unspecified site
0.835 0.165 0.000
B34 Viral infection of unspecified site
0.831 0.169 0.000
A00-A09 Intestinal infectious diseases
0.831 0.169 0.000
C25 Malignant neoplasm of pancreas
0.831 0.169 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.828 0.172 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.824 0.176 0.000
M10.9 Gout, unspecified
0.823 0.177 0.000
F60-F69 Disorders of adult personality and behaviour
0.822 0.178 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.822 0.178 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.821 0.179 0.000
Y45.0 Opioids and related analgesics
0.820 0.180 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.820 0.180 0.000
S90-S99 Injuries to the ankle and foot
0.819 0.181 0.000
M07 Psoriatic and enteropathic arthropathies
0.819 0.181 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.819 0.181 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.818 0.182 0.000
B35-B49 Mycoses
0.816 0.184 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.814 0.186 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.812 0.188 0.000
X20-X29 Contact with venomous animals and plants
0.812 0.188 0.000
A46 Erysipelas
0.811 0.189 0.000
A49.1 Streptococcal infection, unspecified
0.811 0.189 0.000
R26 Abnormalities of gait and mobility
0.810 0.190 0.000
V80-V89 Other land transport accidents
0.810 0.190 0.000
J90-J94 Other diseases of pleura
0.810 0.190 0.000
R80 Isolated proteinuria
0.806 0.194 0.000
C18.5 Splenic flexure
0.806 0.194 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.805 0.195 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.804 0.196 0.000
S10-S19 Injuries to the neck
0.800 0.200 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.799 0.201 0.000
M06.4 Inflammatory polyarthropathy
0.798 0.202 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.797 0.203 0.000
O61 Failed induction of labour
0.797 0.203 0.000
Y40 Systemic antibiotics
0.797 0.203 0.000
O74 Complications of anaesthesia during labour and delivery
0.797 0.203 0.000
B65-B83 Helminthiases
0.797 0.203 0.000
O71 Other obstetric trauma
0.796 0.204 0.000
J43 Emphysema
0.795 0.204 0.000
A40 Streptococcal septicaemia
0.795 0.205 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.795 0.205 0.000
J42 Unspecified chronic bronchitis
0.794 0.206 0.000
Y00-Y09 Assault
0.794 0.206 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.793 0.207 0.000
R25 Abnormal involuntary movements
0.793 0.207 0.000
Y57 Other and unspecified drugs and medicaments
0.793 0.207 0.000
Y43.3 Other antineoplastic drugs
0.793 0.207 0.000
J30-J39 Other diseases of upper respiratory tract
0.792 0.208 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.792 0.208 0.000
O47 False labour
0.791 0.209 0.000
C34 Malignant neoplasm of bronchus and lung
0.790 0.210 0.000
O30 Multiple gestation
0.789 0.211 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.789 0.211 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.789 0.211 0.000
W75-W84 Other accidental threats to breathing
0.788 0.212 0.000
S32 Fracture of lumbar spine and pelvis
0.787 0.213 0.000
O63.0 Prolonged first stage (of labour)
0.787 0.213 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.787 0.213 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.786 0.214 0.000
S20-S29 Injuries to the thorax
0.786 0.214 0.000
C09 Malignant neoplasm of tonsil
0.783 0.217 0.000
B34.9 Viral infection, unspecified
0.777 0.223 0.000
S02 Fracture of skull and facial bones
0.776 0.224 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.776 0.224 0.000
J44 Other chronic obstructive pulmonary disease
0.774 0.226 0.000
T66-T78 Other and unspecified effects of external causes
0.773 0.227 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.772 0.228 0.000
M10.97 Gout, unspecified (Ankle and foot)
0.772 0.228 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.770 0.230 0.000
S00 Superficial injury of head
0.770 0.230 0.000
Y48 Anaesthetics and therapeutic gases
0.770 0.230 0.000
J95-J99 Other diseases of the respiratory system
0.769 0.231 0.000
M41 Scoliosis
0.768 0.232 0.000
O73 Retained placenta and membranes, without haemorrhage
0.768 0.232 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.768 0.232 0.000
M86-M90 Other osteopathies
0.768 0.232 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.767 0.233 0.000
C16 Malignant neoplasm of stomach
0.766 0.234 0.000
F30 Manic episode
0.764 0.236 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.764 0.236 0.000
O45 Premature separation of placenta [abruptio placentae]
0.764 0.236 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.763 0.236 0.000
M06.0 Seronegative rheumatoid arthritis
0.761 0.239 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.759 0.240 0.000
M80-M85 Disorders of bone density and structure
0.759 0.241 0.000
A49.0 Staphylococcal infection, unspecified
0.758 0.242 0.000
X60-X84 Intentional self-harm
0.757 0.243 0.000
T39.1 4-Aminophenol derivatives
0.756 0.244 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.756 0.244 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.756 0.244 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.755 0.245 0.000
J69 Pneumonitis due to solids and liquids
0.755 0.245 0.000
M91-M94 Chondropathies
0.755 0.245 0.000
B99-B99 Other infectious diseases
0.754 0.246 0.000
R82 Other abnormal findings in urine
0.754 0.246 0.000
O66 Other obstructed labour
0.753 0.247 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.753 0.247 0.000
M60-M63 Disorders of muscles
0.753 0.247 0.000
F34 Persistent mood [affective] disorders
0.752 0.248 0.000
W50-W64 Exposure to animate mechanical forces
0.752 0.248 0.000
O43 Placental disorders
0.752 0.248 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.751 0.249 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.750 0.250 0.000
R42 Dizziness and giddiness
0.750 0.250 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.749 0.251 0.000
M11 Other crystal arthropathies
0.748 0.252 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.748 0.252 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.747 0.253 0.000
T90.9 Sequelae of unspecified injury of head
0.747 0.253 0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
0.746 0.254 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.743 0.257 0.000
F99-F99 Unspecified mental disorder
0.742 0.258 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.742 0.258 0.000
Y45.8 Other analgesics and antipyretics
0.740 0.260 0.000
O85-O92 Complications predominantly related to the puerperium
0.737 0.262 0.000
S32.0 Fracture of lumbar vertebra
0.737 0.263 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.737 0.263 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.737 0.263 0.000
Y44.2 Anticoagulants
0.735 0.265 0.000
A49.9 Bacterial infection, unspecified
0.735 0.265 0.000
R25.1 Tremor, unspecified
0.735 0.265 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.734 0.266 0.000
Y45.5 4-Aminophenol derivatives
0.734 0.266 0.000
O42.9 Premature rupture of membranes, unspecified
0.734 0.266 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.733 0.267 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.733 0.267 0.000
T90.1 Sequelae of open wound of head
0.732 0.268 0.000
T46.1 Calcium-channel blockers
0.732 0.268 0.000
A08 Viral and other specified intestinal infections
0.731 0.269 0.000
M00-M03 Infectious arthropathies
0.730 0.269 0.000
M14 Arthropathies in other diseases classified elsewhere
0.730 0.270 0.000
C25.9 Pancreas, unspecified
0.730 0.270 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.730 0.270 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.729 0.271 0.000
M47 Spondylosis
0.729 0.271 0.000
J34 Other disorders of nose and nasal sinuses
0.728 0.272 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.727 0.273 0.000
T98 Sequelae of other and unspecified effects of external causes
0.724 0.276 0.000
C01 Malignant neoplasm of base of tongue
0.724 0.276 0.000
B25 Cytomegaloviral disease
0.724 0.276 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.723 0.277 0.000
F80-F89 Disorders of psychological development
0.722 0.277 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.722 0.278 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.722 0.278 0.000
C18.0 Caecum
0.722 0.278 0.000
A04 Other bacterial intestinal infections
0.721 0.279 0.000
C07 Malignant neoplasm of parotid gland
0.721 0.279 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.720 0.280 0.000
W06 Fall involving bed
0.720 0.280 0.000
M46 Other inflammatory spondylopathies
0.718 0.281 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
F32.0 Mild depressive episode
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.717 0.283 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.717 0.283 0.000
B50-B64 Protozoal diseases
0.717 0.283 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.717 0.283 0.000
A75-A79 Rickettsioses
0.717 0.283 0.000
A70-A74 Other diseases caused by chlamydiae
0.717 0.283 0.000
A65-A69 Other spirochaetal diseases
0.717 0.283 0.000
A20-A28 Certain zoonotic bacterial diseases
0.717 0.283 0.000
A15-A19 Tuberculosis
0.717 0.283 0.000
M12 Other specific arthropathies
0.717 0.283 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.717 0.283 0.000
M08 Juvenile arthritis
0.717 0.283 0.000
A48 Other bacterial diseases, not elsewhere classified
0.716 0.284 0.000
A44 Bartonellosis
0.716 0.284 0.000
A43 Nocardiosis
0.716 0.284 0.000
A42 Actinomycosis
0.716 0.284 0.000
A39 Meningococcal infection
0.716 0.284 0.000
A37 Whooping cough
0.716 0.284 0.000
A36 Diphtheria
0.716 0.284 0.000
A32 Listeriosis
0.716 0.284 0.000
A31 Infection due to other mycobacteria
0.716 0.284 0.000
A30 Leprosy [Hansen's disease]
0.716 0.284 0.000
A38 Scarlet fever
0.716 0.284 0.000
A35 Other tetanus
0.716 0.284 0.000
A34 Obstetrical tetanus
0.716 0.284 0.000
A33 Tetanus neonatorum
0.716 0.284 0.000
M06.8 Other specified rheumatoid arthritis
0.716 0.284 0.000
M06.2 Rheumatoid bursitis
0.716 0.284 0.000
M06.1 Adult-onset Still's disease
0.716 0.284 0.000
Y35-Y36 Legal intervention and operations of war
0.716 0.284 0.000
Y10-Y34 Event of undetermined intent
0.716 0.284 0.000
X85-X99 Assault
0.716 0.284 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.716 0.284 0.000
X30-X39 Exposure to forces of nature
0.716 0.284 0.000
X10-X19 Contact with heat and hot substances
0.716 0.284 0.000
X00-X09 Exposure to smoke, fire and flames
0.716 0.284 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.716 0.284 0.000
W65-W74 Accidental drowning and submersion
0.716 0.284 0.000
V98-V99 Other and unspecified transport accidents
0.716 0.284 0.000
V95-V97 Air and space transport accidents
0.716 0.284 0.000
V90-V94 Water transport accidents
0.716 0.284 0.000
V70-V79 Bus occupant injured in transport accident
0.716 0.284 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.716 0.284 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.716 0.284 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.716 0.284 0.000
V01-V09 Pedestrian injured in transport accident
0.716 0.284 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.716 0.284 0.000
F29 Unspecified nonorganic psychosis
0.716 0.284 0.000
W11 Fall on and from ladder
0.716 0.284 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.716 0.284 0.000
J00-J06 Acute upper respiratory infections
0.715 0.285 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.715 0.285 0.000
Y59 Other and unspecified vaccines and biological substances
0.715 0.285 0.000
Y58 Bacterial vaccines
0.715 0.285 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.715 0.285 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.715 0.285 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.715 0.285 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.715 0.285 0.000
J45 Asthma
0.714 0.286 0.000
M48.0 Spinal stenosis
0.714 0.286 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.713 0.287 0.000
F70-F79 Mental retardation
0.713 0.287 0.000
J34.3 Hypertrophy of nasal turbinates
0.713 0.287 0.000
F38 Other mood [affective] disorders
0.713 0.287 0.000
F39 Unspecified mood [affective] disorder
0.713 0.287 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.713 0.287 0.000
A80-A89 Viral infections of the central nervous system
0.712 0.288 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.712 0.288 0.000
A41.4 Septicaemia due to anaerobes
0.712 0.288 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.712 0.288 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.712 0.288 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.711 0.289 0.000
F31.8 Other bipolar affective disorders
0.710 0.290 0.000
F31.7 Bipolar affective disorder, currently in remission
0.710 0.290 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.710 0.290 0.000
T79.6 Traumatic ischaemia of muscle
0.708 0.292 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.708 0.292 0.000
O60 Preterm delivery
0.708 0.292 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.707 0.292 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.705 0.295 0.000
T31 Burns classified according to extent of body surface involved
0.705 0.295 0.000
M06.34 Rheumatoid nodule (Hand)
0.704 0.295 0.000
J92 Pleural plaque
0.704 0.296 0.000
J30 Vasomotor and allergic rhinitis
0.704 0.296 0.000
O46.9 Antepartum haemorrhage, unspecified
0.703 0.297 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.703 0.297 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.702 0.298 0.000
C09.9 Tonsil, unspecified
0.702 0.298 0.000
S32.00 Fracture of lumbar vertebra (closed)
0.701 0.299 0.000
C04 Malignant neoplasm of floor of mouth
0.701 0.299 0.000
O44 Placenta praevia
0.701 0.299 0.000
M49 Spondylopathies in diseases classified elsewhere
0.700 0.300 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.700 0.300 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.700 0.300 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.700 0.300 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.700 0.300 0.000
T36 Poisoning by systemic antibiotics
0.700 0.300 0.000
Y42.5 Other oestrogens and progestogens
0.700 0.300 0.000
T23 Burn and corrosion of wrist and hand
0.699 0.301 0.000
Y43.1 Antineoplastic antimetabolites
0.699 0.301 0.000
S20 Superficial injury of thorax
0.699 0.301 0.000
Y79 Orthopaedic devices associated with adverse incidents
0.699 0.301 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.697 0.303 0.000
C18.2 Ascending colon
0.696 0.304 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.696 0.304 0.000
W19 Unspecified fall
0.695 0.304 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.695 0.305 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.695 0.305 0.000
J43.9 Emphysema, unspecified
0.694 0.306 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.694 0.306 0.000
Y52.1 Calcium-channel blockers
0.693 0.307 0.000
O63.9 Long labour, unspecified
0.693 0.307 0.000
S05 Injury of eye and orbit
0.693 0.307 0.000
B15-B19 Viral hepatitis
0.693 0.307 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.693 0.307 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.692 0.308 0.000
W07 Fall involving chair
0.692 0.308 0.000
S02.2 Fracture of nasal bones
0.692 0.308 0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
0.692 0.308 0.000
V20-V29 Motorcycle rider injured in transport accident
0.692 0.308 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.691 0.308 0.000
R82.9 Other and unspecified abnormal finding in urine
0.691 0.309 0.000
Y49.5 Other antipsychotics and neuroleptics
0.691 0.309 0.000
F32.8 Other depressive episodes
0.691 0.309 0.000
S08 Traumatic amputation of part of head
0.691 0.309 0.000
S07 Crushing injury of head
0.691 0.309 0.000
S04 Injury of cranial nerves
0.691 0.309 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.691 0.309 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.690 0.310 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.689 0.311 0.000
O63.2 Delayed delivery of second twin, triplet, etc.
0.689 0.311 0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
0.689 0.311 0.000
M07.3 Other psoriatic arthropathies
0.689 0.311 0.000
R47-R49 Symptoms and signs involving speech and voice
0.689 0.311 0.000
M41.9 Scoliosis, unspecified
0.689 0.311 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.688 0.312 0.000
O62 Abnormalities of forces of labour
0.688 0.312 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.688 0.312 0.000
B35 Dermatophytosis
0.688 0.312 0.000
T92 Sequelae of injuries of upper limb
0.687 0.313 0.000
O30.0 Twin pregnancy
0.687 0.313 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.687 0.313 0.000
O97 Death from sequelae of direct obstetric causes
0.687 0.313 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.687 0.313 0.000
O95 Obstetric death of unspecified cause
0.687 0.313 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.687 0.313 0.000
T90.8 Sequelae of other specified injuries of head
0.687 0.313 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.687 0.313 0.000
X50-X57 Overexertion, travel and privation
0.686 0.314 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.685 0.314 0.000
U80 Agent resistant to penicillin and related antibiotics
0.685 0.314 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.685 0.314 0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours
0.685 0.315 0.000
C17 Malignant neoplasm of small intestine
0.685 0.315 0.000
M48.06 Spinal stenosis (Lumbar region)
0.683 0.317 0.000
A49.3 Mycoplasma infection, unspecified
0.682 0.318 0.000
A49.2 Haemophilus influenzae infection, unspecified
0.682 0.318 0.000
R81 Glycosuria
0.681 0.319 0.000
W18 Other fall on same level
0.681 0.319 0.000
Y45.2 Propionic acid derivatives
0.681 0.319 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.680 0.320 0.000
J91 Pleural effusion in conditions classified elsewhere
0.680 0.320 0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium
0.679 0.320 0.000
J11 Influenza, virus not identified
0.679 0.321 0.000
T16 Foreign body in ear
0.679 0.321 0.000
X23 Contact with hornets, wasps and bees
0.678 0.322 0.000
C34.9 Bronchus or lung, unspecified
0.677 0.323 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.677 0.323 0.000
S00.7 Multiple superficial injuries of head
0.676 0.324 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.676 0.324 0.000
S09.7 Multiple injuries of head
0.675 0.325 0.000
S09.2 Traumatic rupture of ear drum
0.675 0.325 0.000
S09.1 Injury of muscle and tendon of head
0.675 0.325 0.000
S09.0 Injury of blood vessels of head, not elsewhere classified
0.675 0.325 0.000
T95 Sequelae of burns, corrosions and frostbite
0.675 0.325 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.675 0.325 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.675 0.325 0.000
V40-V49 Car occupant injured in transport accident
0.675 0.325 0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified
0.674 0.326 0.000
J45.0 Predominantly allergic asthma
0.674 0.326 0.000
Y57.9 Drug or medicament, unspecified
0.673 0.327 0.000
J69.0 Pneumonitis due to food and vomit
0.673 0.327 0.000
Y40.8 Other systemic antibiotics
0.671 0.329 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.671 0.329 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.670 0.330 0.000
T91 Sequelae of injuries of neck and trunk
0.669 0.330 0.000
F60 Specific personality disorders
0.669 0.331 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.668 0.332 0.000
R26.2 Difficulty in walking, not elsewhere classified
0.668 0.332 0.000
W17 Other fall from one level to another
0.668 0.332 0.000
O33 Maternal care for known or suspected disproportion
0.668 0.332 0.000
O31 Complications specific to multiple gestation
0.668 0.332 0.000
T17 Foreign body in respiratory tract
0.667 0.332 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.667 0.333 0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium
0.667 0.333 0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
0.667 0.333 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.666 0.334 0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.665 0.335 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.665 0.335 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.665 0.335 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.665 0.335 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.665 0.335 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.665 0.335 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.665 0.335 0.000
C21 Malignant neoplasm of anus and anal canal
0.665 0.335 0.000
M40 Kyphosis and lordosis
0.665 0.335 0.000
O00-O08 Pregnancy with abortive outcome
0.664 0.336 0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.664 0.336 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.663 0.336 0.000
J92.0 Pleural plaque with presence of asbestos
0.663 0.337 0.000
J30.1 Allergic rhinitis due to pollen
0.663 0.337 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.662 0.338 0.000
C23 Malignant neoplasm of gallbladder
0.662 0.338 0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
0.661 0.338 0.000
R25.3 Fasciculation
0.661 0.339 0.000
O61.0 Failed medical induction of labour
0.661 0.339 0.000
O74.6 Other complications of spinal and epidural anaesthesia during labour and delivery
0.661 0.339 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.660 0.340 0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified
0.659 0.340 0.000
Y45.4 Antirheumatics
0.659 0.340 0.000
C92 Myeloid leukaemia
0.656 0.343 0.000
C24.1 Ampulla of Vater
0.656 0.344 0.000
B33 Other viral diseases, not elsewhere classified
0.655 0.344 0.000
B30 Viral conjunctivitis
0.655 0.344 0.000
B27 Infectious mononucleosis
0.655 0.344 0.000
B26 Mumps
0.655 0.344 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.655 0.344 0.000
C10 Malignant neoplasm of oropharynx
0.655 0.345 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.655 0.345 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.654 0.346 0.000
M43 Other deforming dorsopathies
0.654 0.346 0.000
T78 Adverse effects, not elsewhere classified
0.653 0.347 0.000
C25.0 Head of pancreas
0.653 0.347 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.653 0.347 0.000
C18.1 Appendix
0.653 0.347 0.000
C34.1 Upper lobe, bronchus or lung
0.653 0.347 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.652 0.348 0.000
B80 Enterobiasis
0.651 0.349 0.000
J41 Simple and mucopurulent chronic bronchitis
0.650 0.350 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.649 0.351 0.000
S90 Superficial injury of ankle and foot
0.649 0.351 0.000
T20 Burn and corrosion of head and neck
0.649 0.351 0.000
T90.3 Sequelae of injury of cranial nerves
0.649 0.351 0.000
T90.0 Sequelae of superficial injury of head
0.649 0.351 0.000
C15 Malignant neoplasm of oesophagus
0.649 0.351 0.000
C18.8 Overlapping lesion of colon
0.649 0.351 0.000
T63 Toxic effect of contact with venomous animals
0.649 0.351 0.000
Q00-Q07 Congenital malformations of the nervous system
0.647 0.353 0.000
Y04 Assault by bodily force
0.647 0.353 0.000
R26.3 Immobility
0.647 0.353 0.000
M10.99 Gout, unspecified (Site unspecified)
0.646 0.353 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.646 0.354 0.000
S09.8 Other specified injuries of head
0.646 0.354 0.000
S37 Injury of urinary and pelvic organs
0.645 0.355 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.644 0.356 0.000
S92 Fracture of foot, except ankle
0.644 0.356 0.000
O45.9 Premature separation of placenta, unspecified
0.643 0.356 0.000
T90.5 Sequelae of intracranial injury
0.643 0.357 0.000
M10.4 Other secondary gout
0.643 0.357 0.000
M10.3 Gout due to impairment of renal function
0.643 0.357 0.000
M10.2 Drug-induced gout
0.643 0.357 0.000
M10.1 Lead-induced gout
0.643 0.357 0.000
M10.0 Idiopathic gout
0.643 0.357 0.000
C13 Malignant neoplasm of hypopharynx
0.643 0.357 0.000
C11 Malignant neoplasm of nasopharynx
0.643 0.357 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.643 0.357 0.000
C06 Malignant neoplasm of other and unspecified parts of mouth
0.643 0.357 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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