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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs74986892
log Bayes Factor = 9.97307
Chromosome 17   position 12,326,683  (GRCh37) Explore rs74986892 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.999 0.001 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.993 0.007 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.993 0.007 0.000
Chapter XI Diseases of the digestive system
0.992 0.008 0.000
Chapter I Certain infectious and parasitic diseases
0.988 0.012 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.974 0.026 0.000
Chapter IX Diseases of the circulatory system
0.971 0.029 0.000
S80-S89 Injuries to the knee and lower leg
0.968 0.032 0.000
K86 Other diseases of pancreas
0.966 0.034 0.000
K90-K93 Other diseases of the digestive system
0.958 0.042 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.957 0.043 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.957 0.043 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.952 0.048 0.000
I60-I69 Cerebrovascular diseases
0.950 0.050 0.000
S80 Superficial injury of lower leg
0.948 0.052 0.000
K50-K52 Noninfective enteritis and colitis
0.944 0.056 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.943 0.057 0.000
K86.1 Other chronic pancreatitis
0.938 0.062 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.938 0.062 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.938 0.062 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.932 0.068 0.000
B95-B98 Bacterial, viral and other infectious agents
0.929 0.071 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.928 0.072 0.000
K50 Crohn's disease [regional enteritis]
0.925 0.075 0.000
S80.9 Superficial injury of lower leg, unspecified
0.920 0.080 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.920 0.080 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.919 0.081 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.918 0.082 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.916 0.084 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.915 0.085 0.000
L40-L45 Papulosquamous disorders
0.912 0.088 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.911 0.089 0.000
L50-L54 Urticaria and erythema
0.906 0.094 0.000
S60-S69 Injuries to the wrist and hand
0.901 0.099 0.000
T86 Failure and rejection of transplanted organs and tissues
0.900 0.100 0.000
S40-S49 Injuries to the shoulder and upper arm
0.896 0.104 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.895 0.105 0.000
K50.9 Crohn's disease, unspecified
0.895 0.105 0.000
I77 Other disorders of arteries and arterioles
0.890 0.110 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.889 0.111 0.000
Chapter II Neoplasms
0.883 0.117 0.000
I67 Other cerebrovascular diseases
0.883 0.117 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.883 0.117 0.000
W20-W49 Exposure to inanimate mechanical forces
0.881 0.119 0.000
K91.3 Postoperative intestinal obstruction
0.881 0.119 0.000
Q80-Q89 Other congenital malformations
0.878 0.122 0.000
K65-K67 Diseases of peritoneum
0.877 0.123 0.000
K90 Intestinal malabsorption
0.875 0.124 0.000
T87 Complications peculiar to reattachment and amputation
0.875 0.125 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.869 0.131 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.868 0.132 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.866 0.134 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.864 0.136 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.863 0.137 0.000
T66-T78 Other and unspecified effects of external causes
0.862 0.138 0.000
L40 Psoriasis
0.861 0.139 0.000
Y95 Nosocomial condition
0.860 0.140 0.000
T81 Complications of procedures, not elsewhere classified
0.857 0.143 0.000
S90-S99 Injuries to the ankle and foot
0.853 0.147 0.000
A30-A49 Other bacterial diseases
0.852 0.148 0.000
Y83.3 Surgical operation with formation of external stoma
0.847 0.153 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.847 0.153 0.000
K86.8 Other specified diseases of pancreas
0.846 0.154 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.846 0.154 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.845 0.155 0.000
Y83.5 Amputation of limb(s)
0.844 0.156 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.843 0.157 0.000
Y83.8 Other surgical procedures
0.839 0.161 0.000
Q60-Q64 Congenital malformations of the urinary system
0.838 0.162 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.838 0.162 0.000
L90 Atrophic disorders of skin
0.837 0.163 0.000
I74 Arterial embolism and thrombosis
0.832 0.168 0.000
L89 Decubitus ulcer
0.830 0.170 0.000
B07 Viral warts
0.829 0.171 0.000
D00-D09 In situ neoplasms
0.829 0.171 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.828 0.172 0.000
T93 Sequelae of injuries of lower limb
0.826 0.174 0.000
K90.0 Coeliac disease
0.825 0.175 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.823 0.177 0.000
K83 Other diseases of biliary tract
0.822 0.178 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.816 0.184 0.000
K50.8 Other Crohn's disease
0.814 0.185 0.000
Y88 Sequelae of surgical and medical care as external cause
0.812 0.188 0.000
C15-C26 Malignant neoplasms of digestive organs
0.810 0.190 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.810 0.190 0.000
Y52 Agents primarily affecting the cardiovascular system
0.807 0.193 0.000
L40.5 Arthropathic psoriasis
0.806 0.194 0.000
Chapter X Diseases of the respiratory system
0.806 0.194 0.000
X50-X57 Overexertion, travel and privation
0.804 0.195 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.804 0.196 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.801 0.199 0.000
Y83.4 Other reconstructive surgery
0.799 0.201 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.799 0.201 0.000
I77.1 Stricture of artery
0.796 0.204 0.000
K35-K38 Diseases of appendix
0.796 0.204 0.000
L53 Other erythematous conditions
0.796 0.204 0.000
J09-J18 Influenza and pneumonia
0.796 0.204 0.000
Q50-Q56 Congenital malformations of genital organs
0.795 0.205 0.000
I70 Atherosclerosis
0.795 0.205 0.000
S80.8 Other superficial injuries of lower leg
0.795 0.205 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.792 0.208 0.000
Chapter VI Diseases of the nervous system
0.791 0.209 0.000
S64 Injury of nerves at wrist and hand level
0.791 0.209 0.000
K86.2 Cyst of pancreas
0.789 0.210 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.784 0.216 0.000
T91 Sequelae of injuries of neck and trunk
0.782 0.218 0.000
L08 Other local infections of skin and subcutaneous tissue
0.782 0.218 0.000
L84 Corns and callosities
0.780 0.220 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.780 0.220 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.780 0.220 0.000
K70-K77 Diseases of liver
0.778 0.222 0.000
K65 Peritonitis
0.778 0.222 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.777 0.223 0.000
J18 Pneumonia, organism unspecified
0.777 0.223 0.000
T78 Adverse effects, not elsewhere classified
0.776 0.224 0.000
A00-A09 Intestinal infectious diseases
0.773 0.227 0.000
Chapter XXII Codes for special purposes
0.773 0.227 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.772 0.228 0.000
B35-B49 Mycoses
0.771 0.229 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.768 0.231 0.000
T86.1 Kidney transplant failure and rejection
0.766 0.234 0.000
D05 Carcinoma in situ of breast
0.766 0.234 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.765 0.235 0.000
W29 Contact with other powered hand tools and household machinery
0.764 0.236 0.000
I62 Other nontraumatic intracranial haemorrhage
0.764 0.236 0.000
Y85 Sequelae of transport accidents
0.763 0.237 0.000
I67.1 Cerebral aneurysm, nonruptured
0.763 0.237 0.000
J18.9 Pneumonia, unspecified
0.762 0.238 0.000
V40-V49 Car occupant injured in transport accident
0.762 0.238 0.000
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure
0.761 0.239 0.000
K91.0 Vomiting following gastro-intestinal surgery
0.759 0.241 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.757 0.243 0.000
L52 Erythema nodosum
0.756 0.244 0.000
K81 Cholecystitis
0.756 0.244 0.000
E70-E90 Metabolic disorders
0.756 0.244 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.755 0.245 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.754 0.245 0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.753 0.247 0.000
I78 Diseases of capillaries
0.750 0.250 0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems
0.749 0.251 0.000
L80 Vitiligo
0.749 0.251 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.749 0.251 0.000
L20-L30 Dermatitis and eczema
0.748 0.252 0.000
K86.3 Pseudocyst of pancreas
0.748 0.252 0.000
T92 Sequelae of injuries of upper limb
0.747 0.253 0.000
T18 Foreign body in alimentary tract
0.747 0.253 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.746 0.254 0.000
I77.6 Arteritis, unspecified
0.745 0.255 0.000
C64-C68 Malignant neoplasms of urinary tract
0.744 0.256 0.000
Y83.9 Surgical procedure, unspecified
0.744 0.256 0.000
S10-S19 Injuries to the neck
0.743 0.256 0.000
V20-V29 Motorcycle rider injured in transport accident
0.743 0.257 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.742 0.257 0.000
S66.8 Injury of other muscles and tendons at wrist and hand level
0.742 0.258 0.000
T82.3 Mechanical complication of other vascular grafts
0.741 0.258 0.000
T21 Burn and corrosion of trunk
0.740 0.260 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.740 0.260 0.000
T78.4 Allergy, unspecified
0.738 0.262 0.000
K91.4 Colostomy and enterostomy malfunction
0.738 0.262 0.000
B99-B99 Other infectious diseases
0.738 0.262 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.737 0.263 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.737 0.263 0.000
I72 Other aneurysm
0.737 0.263 0.000
K35 Acute appendicitis
0.735 0.265 0.000
V80-V89 Other land transport accidents
0.734 0.266 0.000
Y83.0 Surgical operation with transplant of whole organ
0.734 0.266 0.000
I67.8 Other specified cerebrovascular diseases
0.734 0.266 0.000
X60-X84 Intentional self-harm
0.734 0.266 0.000
C34 Malignant neoplasm of bronchus and lung
0.732 0.268 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.732 0.268 0.000
W50-W64 Exposure to animate mechanical forces
0.730 0.270 0.000
I27 Other pulmonary heart diseases
0.730 0.270 0.000
I26 Pulmonary embolism
0.729 0.271 0.000
K86.0 Alcohol-induced chronic pancreatitis
0.728 0.272 0.000
S89 Other and unspecified injuries of lower leg
0.728 0.272 0.000
Chapter XIV Diseases of the genitourinary system
0.725 0.275 0.000
T87.4 Infection of amputation stump
0.725 0.275 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.725 0.275 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.724 0.276 0.000
S41 Open wound of shoulder and upper arm
0.724 0.276 0.000
L40.9 Psoriasis, unspecified
0.723 0.277 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.723 0.277 0.000
K50.1 Crohn's disease of large intestine
0.721 0.279 0.000
T86.8 Failure and rejection of other transplanted organs and tissues
0.721 0.279 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.721 0.279 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.720 0.280 0.000
B15-B19 Viral hepatitis
0.719 0.281 0.000
D09 Carcinoma in situ of other and unspecified sites
0.718 0.282 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.717 0.283 0.000
Y10-Y34 Event of undetermined intent
0.717 0.283 0.000
Y00-Y09 Assault
0.717 0.283 0.000
X85-X99 Assault
0.717 0.283 0.000
X30-X39 Exposure to forces of nature
0.717 0.283 0.000
X10-X19 Contact with heat and hot substances
0.717 0.283 0.000
X00-X09 Exposure to smoke, fire and flames
0.717 0.283 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.717 0.283 0.000
W75-W84 Other accidental threats to breathing
0.717 0.283 0.000
W65-W74 Accidental drowning and submersion
0.717 0.283 0.000
V98-V99 Other and unspecified transport accidents
0.717 0.283 0.000
V95-V97 Air and space transport accidents
0.717 0.283 0.000
V90-V94 Water transport accidents
0.717 0.283 0.000
V70-V79 Bus occupant injured in transport accident
0.717 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.717 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.717 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.717 0.283 0.000
V01-V09 Pedestrian injured in transport accident
0.717 0.283 0.000
Q65 Congenital deformities of hip
0.716 0.284 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.715 0.285 0.000
L89.2 Stage III decubitus ulcer
0.714 0.286 0.000
T87.3 Neuroma of amputation stump
0.713 0.287 0.000
Q00-Q07 Congenital malformations of the nervous system
0.713 0.287 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.713 0.287 0.000
L10-L14 Bullous disorders
0.712 0.288 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.712 0.288 0.000
Q35-Q37 Cleft lip and cleft palate
0.712 0.288 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.712 0.288 0.000
L90.5 Scar conditions and fibrosis of skin
0.711 0.289 0.000
T86.0 Bone-marrow transplant rejection
0.710 0.290 0.000
Q61 Cystic kidney disease
0.710 0.290 0.000
V10-V19 Pedal cyclist injured in transport accident
0.710 0.290 0.000
L90.0 Lichen sclerosus et atrophicus
0.709 0.291 0.000
K83.8 Other specified diseases of biliary tract
0.709 0.291 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.708 0.292 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.708 0.292 0.000
B65-B83 Helminthiases
0.708 0.292 0.000
B50-B64 Protozoal diseases
0.708 0.292 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.708 0.292 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.708 0.292 0.000
A75-A79 Rickettsioses
0.708 0.292 0.000
A70-A74 Other diseases caused by chlamydiae
0.708 0.292 0.000
A65-A69 Other spirochaetal diseases
0.708 0.292 0.000
A20-A28 Certain zoonotic bacterial diseases
0.708 0.292 0.000
A15-A19 Tuberculosis
0.708 0.292 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.708 0.292 0.000
S80.1 Contusion of other and unspecified parts of lower leg
0.708 0.292 0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level
0.708 0.292 0.000
Y42.7 Androgens and anabolic congeners
0.707 0.293 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.706 0.293 0.000
D06 Carcinoma in situ of cervix uteri
0.706 0.294 0.000
K86.9 Disease of pancreas, unspecified
0.705 0.295 0.000
Q27 Other congenital malformations of peripheral vascular system
0.704 0.296 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.704 0.296 0.000
I61 Intracerebral haemorrhage
0.703 0.297 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.703 0.297 0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.702 0.298 0.000
X20-X29 Contact with venomous animals and plants
0.700 0.299 0.000
A49 Bacterial infection of unspecified site
0.699 0.301 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.699 0.301 0.000
K35.0 Acute appendicitis with generalised peritonitis
0.699 0.301 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.698 0.302 0.000
G30-G32 Other degenerative diseases of the nervous system
0.698 0.302 0.000
S50-S59 Injuries to the elbow and forearm
0.698 0.302 0.000
L53.9 Erythematous condition, unspecified
0.697 0.303 0.000
K70 Alcoholic liver disease
0.697 0.303 0.000
I05-I09 Chronic rheumatic heart diseases
0.696 0.304 0.000
I00-I02 Acute rheumatic fever
0.696 0.304 0.000
Q82 Other congenital malformations of skin
0.696 0.304 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.696 0.304 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.694 0.305 0.000
Q66 Congenital deformities of feet
0.694 0.306 0.000
S88 Traumatic amputation of lower leg
0.694 0.306 0.000
S87 Crushing injury of lower leg
0.694 0.306 0.000
S86 Injury of muscle and tendon at lower leg level
0.694 0.306 0.000
S85 Injury of blood vessels at lower leg level
0.694 0.306 0.000
S84 Injury of nerves at lower leg level
0.694 0.306 0.000
S91 Open wound of ankle and foot
0.694 0.306 0.000
L83 Acanthosis nigricans
0.693 0.306 0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.693 0.307 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.692 0.308 0.000
I77.0 Arteriovenous fistula, acquired
0.692 0.308 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.691 0.309 0.000
I67.2 Cerebral atherosclerosis
0.691 0.309 0.000
C17 Malignant neoplasm of small intestine
0.691 0.309 0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level
0.691 0.309 0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue
0.690 0.310 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.689 0.311 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.688 0.312 0.000
T90 Sequelae of injuries of head
0.687 0.313 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.687 0.313 0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft
0.686 0.314 0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract
0.686 0.314 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.686 0.314 0.000
T83.2 Mechanical complication of graft of urinary organ
0.686 0.314 0.000
S40 Superficial injury of shoulder and upper arm
0.686 0.314 0.000
I60 Subarachnoid haemorrhage
0.685 0.314 0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level
0.682 0.317 0.000
B00 Herpesviral [herpes simplex] infections
0.681 0.318 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.681 0.319 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.681 0.319 0.000
S65 Injury of blood vessels at wrist and hand level
0.681 0.319 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.681 0.319 0.000
C34.3 Lower lobe, bronchus or lung
0.680 0.320 0.000
W29.9 Unspecified place
0.680 0.320 0.000
S80.7 Multiple superficial injuries of lower leg
0.680 0.320 0.000
S80.0 Contusion of knee
0.680 0.320 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.679 0.321 0.000
E16 Other disorders of pancreatic internal secretion
0.678 0.322 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.678 0.322 0.000
T18.1 Foreign body in oesophagus
0.678 0.322 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.677 0.323 0.000
Y85.0 Sequelae of motor-vehicle accident
0.677 0.323 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.676 0.323 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.676 0.323 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.676 0.323 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.676 0.323 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.676 0.323 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.676 0.324 0.000
W21 Striking against or struck by sports equipment
0.676 0.324 0.000
T79-T79 Certain early complications of trauma
0.676 0.324 0.000
Q23 Congenital malformations of aortic and mitral valves
0.675 0.325 0.000
L89.3 Stage IV decubitus ulcer
0.674 0.326 0.000
X59 Exposure to unspecified factor
0.673 0.326 0.000
C25 Malignant neoplasm of pancreas
0.673 0.327 0.000
T98 Sequelae of other and unspecified effects of external causes
0.672 0.327 0.000
T95 Sequelae of burns, corrosions and frostbite
0.672 0.327 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.672 0.327 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.672 0.327 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.672 0.327 0.000
K66 Other disorders of peritoneum
0.672 0.328 0.000
Q21 Congenital malformations of cardiac septa
0.672 0.328 0.000
N60-N64 Disorders of breast
0.670 0.330 0.000
T24.2 Burn of second degree of hip and lower limb, except ankle and foot
0.670 0.330 0.000
Q89 Other congenital malformations, not elsewhere classified
0.670 0.330 0.000
Y43 Primarily systemic agents
0.669 0.331 0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics
0.669 0.331 0.000
Q24 Other congenital malformations of heart
0.669 0.331 0.000
A41 Other septicaemia
0.669 0.331 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.668 0.332 0.000
L94 Other localised connective tissue disorders
0.668 0.332 0.000
L87 Transepidermal elimination disorders
0.668 0.332 0.000
L88 Pyoderma gangrenosum
0.668 0.332 0.000
L86 Keratoderma in diseases classified elsewhere
0.668 0.332 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.666 0.334 0.000
Y59 Other and unspecified vaccines and biological substances
0.665 0.334 0.000
Y58 Bacterial vaccines
0.665 0.334 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.665 0.334 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.665 0.334 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.665 0.334 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.665 0.334 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.665 0.334 0.000
Y48 Anaesthetics and therapeutic gases
0.665 0.334 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.665 0.334 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.665 0.334 0.000
G20-G26 Extrapyramidal and movement disorders
0.665 0.335 0.000
S20-S29 Injuries to the thorax
0.665 0.335 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.665 0.335 0.000
X50 Overexertion and strenuous or repetitive movements
0.665 0.335 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.664 0.336 0.000
T24.3 Burn of third degree of hip and lower limb, except ankle and foot
0.664 0.336 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.664 0.336 0.000
K65.0 Acute peritonitis
0.663 0.337 0.000
T93.1 Sequelae of fracture of femur
0.662 0.338 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.662 0.338 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.662 0.338 0.000
S64.3 Injury of digital nerve of thumb
0.661 0.339 0.000
T25 Burn and corrosion of ankle and foot
0.659 0.341 0.000
T23 Burn and corrosion of wrist and hand
0.659 0.341 0.000
T20 Burn and corrosion of head and neck
0.659 0.341 0.000
A80-A89 Viral infections of the central nervous system
0.659 0.341 0.000
S92 Fracture of foot, except ankle
0.659 0.341 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.658 0.342 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.658 0.342 0.000
Y98 Lifestyle-related condition
0.658 0.342 0.000
Y97 Environmental-pollution-related condition
0.658 0.342 0.000
Y96 Work-related condition
0.658 0.342 0.000
C16 Malignant neoplasm of stomach
0.658 0.342 0.000
S82 Fracture of lower leg, including ankle
0.658 0.342 0.000
K91.9 Postprocedural disorder of digestive system, unspecified
0.657 0.343 0.000
K91.5 Postcholecystectomy syndrome
0.657 0.343 0.000
K91.2 Postsurgical malabsorption, not elsewhere classified
0.657 0.343 0.000
K91.1 Postgastric surgery syndromes
0.657 0.343 0.000
Q87.4 Marfan's syndrome
0.657 0.343 0.000
L50 Urticaria
0.657 0.343 0.000
I69 Sequelae of cerebrovascular disease
0.657 0.343 0.000
W25 Contact with sharp glass
0.656 0.344 0.000
N25-N29 Other disorders of kidney and ureter
0.656 0.344 0.000
S90 Superficial injury of ankle and foot
0.655 0.345 0.000
C15 Malignant neoplasm of oesophagus
0.654 0.346 0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level
0.654 0.346 0.000
L44 Other papulosquamous disorders
0.654 0.346 0.000
L41 Parapsoriasis
0.654 0.346 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.654 0.346 0.000
L42 Pityriasis rosea
0.654 0.346 0.000
E88 Other metabolic disorders
0.654 0.346 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.653 0.347 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.653 0.347 0.000
T87.6 Other and unspecified complications of amputation stump
0.653 0.347 0.000
Y44 Agents primarily affecting blood constituents
0.652 0.348 0.000
J18.0 Bronchopneumonia, unspecified
0.652 0.348 0.000
W00-W19 Falls
0.651 0.349 0.000
E20-E35 Disorders of other endocrine glands
0.651 0.349 0.000
E86 Volume depletion
0.651 0.349 0.000
L54 Erythema in diseases classified elsewhere
0.649 0.350 0.000
L51 Erythema multiforme
0.649 0.350 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.648 0.352 0.000
A46 Erysipelas
0.648 0.352 0.000
W44 Foreign body entering into or through eye or natural orifice
0.647 0.353 0.000
E40-E46 Malnutrition
0.647 0.353 0.000
W49 Exposure to other and unspecified inanimate mechanical forces
0.647 0.353 0.000
K51 Ulcerative colitis
0.646 0.354 0.000
K83.0 Cholangitis
0.646 0.354 0.000
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified
0.646 0.354 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.646 0.354 0.000
Y52.1 Calcium-channel blockers
0.646 0.354 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.646 0.354 0.000
T86.9 Failure and rejection of unspecified transplanted organ and tissue
0.645 0.354 0.000
T86.4 Liver transplant failure and rejection
0.645 0.354 0.000
T86.3 Heart-lung transplant failure and rejection
0.645 0.354 0.000
T86.2 Heart transplant failure and rejection
0.645 0.354 0.000
L89.9 Decubitus ulcer and pressure area, unspecified
0.644 0.356 0.000
S48 Traumatic amputation of shoulder and upper arm
0.642 0.358 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.642 0.358 0.000
S44 Injury of nerves at shoulder and upper arm level
0.642 0.358 0.000
S47 Crushing injury of shoulder and upper arm
0.642 0.358 0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.642 0.358 0.000
B06 Rubella [German measles]
0.642 0.358 0.000
B05 Measles
0.642 0.358 0.000
B01 Varicella [chickenpox]
0.642 0.358 0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions
0.642 0.358 0.000
B04 Monkeypox
0.642 0.358 0.000
B03 Smallpox
0.642 0.358 0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.641 0.358 0.000
Y57 Other and unspecified drugs and medicaments
0.641 0.359 0.000
O00-O08 Pregnancy with abortive outcome
0.641 0.359 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.641 0.359 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.640 0.360 0.000
Y40 Systemic antibiotics
0.640 0.360 0.000
L93 Lupus erythematosus
0.640 0.360 0.000
I77.5 Necrosis of artery
0.638 0.362 0.000
I77.4 Coeliac artery compression syndrome
0.638 0.362 0.000
I77.3 Arterial fibromuscular dysplasia
0.638 0.362 0.000
I77.2 Rupture of artery
0.638 0.362 0.000
K65.9 Peritonitis, unspecified
0.638 0.362 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.638 0.362 0.000
D09.0 Bladder
0.638 0.362 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.636 0.363 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.636 0.364 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.636 0.364 0.000
L08.8 Other specified local infections of skin and subcutaneous tissue
0.636 0.364 0.000
C66 Malignant neoplasm of ureter
0.634 0.366 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.633 0.367 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.633 0.367 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.633 0.367 0.000
I67.5 Moyamoya disease
0.633 0.367 0.000
I67.4 Hypertensive encephalopathy
0.633 0.367 0.000
I67.3 Progressive vascular leukoencephalopathy
0.633 0.367 0.000
A04 Other bacterial intestinal infections
0.633 0.367 0.000
T92.2 Sequelae of fracture at wrist and hand level
0.633 0.367 0.000
Y89 Sequelae of other external causes
0.633 0.367 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.633 0.367 0.000
Q63 Other congenital malformations of kidney
0.633 0.367 0.000
S43.0 Dislocation of shoulder joint
0.633 0.367 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.632 0.368 0.000
W46 Contact with hypodermic needle
0.632 0.368 0.000
W45 Foreign body or object entering through skin
0.632 0.368 0.000
W43 Exposure to vibration
0.632 0.368 0.000
W42 Exposure to noise
0.632 0.368 0.000
W41 Exposure to high-pressure jet
0.632 0.368 0.000
W40 Explosion of other materials
0.632 0.368 0.000
W39 Discharge of firework
0.632 0.368 0.000
W38 Explosion and rupture of other specified pressurised devices
0.632 0.368 0.000
W37 Explosion and rupture of pressurised tyre, pipe or hose
0.632 0.368 0.000
W36 Explosion and rupture of gas cylinder
0.632 0.368 0.000
W35 Explosion and rupture of boiler
0.632 0.368 0.000
W34 Discharge from other and unspecified firearms
0.632 0.368 0.000
W33 Rifle, shotgun and larger firearm discharge
0.632 0.368 0.000
W32 Handgun discharge
0.632 0.368 0.000
W31 Contact with other and unspecified machinery
0.632 0.368 0.000
W30 Contact with agricultural machinery
0.632 0.368 0.000
W28 Contact with powered lawn mower
0.632 0.368 0.000
W27 Contact with nonpowered hand tool
0.632 0.368 0.000
W26 Contact with knife, sword or dagger
0.632 0.368 0.000
W24 Contact with lifting and transmission devices, not elsewhere classified
0.632 0.368 0.000
W23 Caught, crushed, jammed or pinched in or between objects
0.632 0.368 0.000
W20 Struck by thrown, projected or falling object
0.632 0.368 0.000
T93.2 Sequelae of other fractures of lower limb
0.632 0.368 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.632 0.368 0.000
I77.8 Other specified disorders of arteries and arterioles
0.632 0.368 0.000
S81 Open wound of lower leg
0.630 0.370 0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified
0.629 0.370 0.000
Q84 Other congenital malformations of integument
0.629 0.370 0.000
Q83 Congenital malformations of breast
0.629 0.370 0.000
Q81 Epidermolysis bullosa
0.629 0.370 0.000
Q80 Congenital ichthyosis
0.629 0.370 0.000
C60-C63 Malignant neoplasms of male genital organs
0.629 0.371 0.000
I73 Other peripheral vascular diseases
0.629 0.371 0.000
K67 Disorders of peritoneum in infectious diseases classified elsewhere
0.629 0.371 0.000
Q51 Congenital malformations of uterus and cervix
0.629 0.371 0.000
L89.0 Stage I decubitus ulcer and pressure area
0.629 0.371 0.000
O85-O92 Complications predominantly related to the puerperium
0.628 0.371 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.628 0.372 0.000
K70.9 Alcoholic liver disease, unspecified
0.628 0.372 0.000
K90.8 Other intestinal malabsorption
0.628 0.372 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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