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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs75585141
log Bayes Factor = 14.4069
Chromosome 9   position 13,387,483  (GRCh37) Explore rs75585141 on Ensembl!
Variant rs75585141 is part of Cluster X0070

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.998 0.002 0.000
Chapter V Mental and behavioural disorders
0.997 0.003 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.997 0.003 0.000
W00-W19 Falls
0.996 0.004 0.000
K70-K77 Diseases of liver
0.996 0.004 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.991 0.009 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.990 0.010 0.000
E70-E90 Metabolic disorders
0.990 0.010 0.000
Chapter XIV Diseases of the genitourinary system
0.988 0.012 0.000
K50-K52 Noninfective enteritis and colitis
0.986 0.014 0.000
W19 Unspecified fall
0.986 0.014 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.984 0.016 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.984 0.016 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.981 0.019 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.973 0.027 0.000
K52 Other non-infective gastro-enteritis and colitis
0.973 0.027 0.000
N17-N19 Renal failure
0.971 0.029 0.000
K55-K64 Other diseases of intestines
0.968 0.032 0.000
F10.2 Dependence syndrome
0.967 0.033 0.000
K57 Diverticular disease of intestine
0.964 0.036 0.000
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.962 0.038 0.000
N10-N16 Renal tubulo-interstitial diseases
0.958 0.042 0.000
R15 Faecal incontinence
0.956 0.044 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.956 0.044 0.000
W19.9 Unspecified place
0.955 0.045 0.000
Chapter I Certain infectious and parasitic diseases
0.952 0.048 0.000
K57.3 Diverticular disease of large intestine without perforation or abscess
0.949 0.051 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.945 0.055 0.000
E87.6 Hypokalaemia
0.945 0.055 0.000
R17 Unspecified jaundice
0.944 0.056 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.941 0.059 0.000
R19.5 Other fecal abnormalities
0.939 0.061 0.000
N13 Obstructive and reflux uropathy
0.929 0.071 0.000
Chapter VII Diseases of the eye and adnexa
0.929 0.071 0.000
K76 Other diseases of liver
0.925 0.075 0.000
K70 Alcoholic liver disease
0.917 0.083 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.917 0.083 0.000
S00-S09 Injuries to the head
0.912 0.088 0.000
K74 Fibrosis and cirrhosis of liver
0.906 0.094 0.000
W19.4 Street and highway
0.904 0.095 0.000
E87.5 Hyperkalaemia
0.904 0.096 0.000
E83 Disorders of mineral metabolism
0.901 0.099 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.899 0.101 0.000
F10.1 Harmful use
0.897 0.103 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.897 0.103 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.895 0.105 0.000
N18 Chronic renal failure
0.892 0.108 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.885 0.115 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.884 0.116 0.000
N17 Acute renal failure
0.883 0.117 0.000
M05-M14 Inflammatory polyarthropathies
0.882 0.118 0.000
R14 Flatulence and related conditions
0.878 0.122 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.871 0.129 0.000
K51 Ulcerative colitis
0.869 0.131 0.000
S70-S79 Injuries to the hip and thigh
0.867 0.133 0.000
K65-K67 Diseases of peritoneum
0.866 0.134 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.861 0.139 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.861 0.139 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.861 0.139 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.858 0.142 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.858 0.142 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.857 0.143 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.856 0.144 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.856 0.144 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.850 0.150 0.000
K75 Other inflammatory liver diseases
0.849 0.151 0.000
N25-N29 Other disorders of kidney and ureter
0.848 0.152 0.000
K86 Other diseases of pancreas
0.847 0.153 0.000
A30-A49 Other bacterial diseases
0.845 0.155 0.000
K57.2 Diverticular disease of large intestine with perforation and abscess
0.844 0.156 0.000
N19 Unspecified renal failure
0.844 0.156 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.843 0.157 0.000
K74.6 Other and unspecified cirrhosis of liver
0.841 0.159 0.000
K85 Acute pancreatitis
0.836 0.164 0.000
K76.6 Portal hypertension
0.836 0.164 0.000
Y95 Nosocomial condition
0.827 0.173 0.000
K82 Other diseases of gallbladder
0.822 0.178 0.000
N17.9 Acute renal failure, unspecified
0.819 0.181 0.000
W06 Fall involving bed
0.818 0.182 0.000
N99-N99 Other disorders of the genitourinary system
0.818 0.182 0.000
K65 Peritonitis
0.811 0.189 0.000
A00-A09 Intestinal infectious diseases
0.810 0.190 0.000
R47-R49 Symptoms and signs involving speech and voice
0.808 0.192 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.806 0.194 0.000
M06 Other rheumatoid arthritis
0.805 0.195 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.803 0.197 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.802 0.198 0.000
Chapter IX Diseases of the circulatory system
0.800 0.200 0.000
S80-S89 Injuries to the knee and lower leg
0.800 0.200 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.800 0.200 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.799 0.201 0.000
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess
0.799 0.201 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.799 0.201 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.798 0.202 0.000
W13 Fall from, out of or through building or structure
0.793 0.207 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.790 0.210 0.000
S06 Intracranial injury
0.789 0.211 0.000
M86-M90 Other osteopathies
0.789 0.211 0.000
N18.3 Chronic kidney disease, stage 3
0.788 0.212 0.000
H55-H59 Other disorders of eye and adnexa
0.787 0.213 0.000
N13.3 Other and unspecified hydronephrosis
0.786 0.214 0.000
W10 Fall on and from stairs and steps
0.786 0.214 0.000
F30-F39 Mood [affective] disorders
0.785 0.215 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.782 0.218 0.000
R18 Ascites
0.782 0.218 0.000
K70.3 Alcoholic cirrhosis of liver
0.780 0.220 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.780 0.220 0.000
K55 Vascular disorders of intestine
0.778 0.222 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.777 0.223 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.775 0.225 0.000
E83.5 Disorders of calcium metabolism
0.774 0.225 0.000
K51.9 Ulcerative colitis, unspecified
0.774 0.226 0.000
X50-X57 Overexertion, travel and privation
0.774 0.226 0.000
R16.1 Splenomegaly, not elsewhere classified
0.772 0.228 0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation
0.771 0.229 0.000
S40-S49 Injuries to the shoulder and upper arm
0.770 0.230 0.000
F10.0 Acute intoxication
0.770 0.230 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.769 0.231 0.000
R19.0 Intra-abdominal and pelvic swelling, mass and lump
0.767 0.233 0.000
T43.2 Other and unspecified antidepressants
0.766 0.234 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.764 0.236 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.763 0.237 0.000
M20-M25 Other joint disorders
0.763 0.237 0.000
S00 Superficial injury of head
0.763 0.237 0.000
K52.1 Toxic gastro-enteritis and colitis
0.759 0.241 0.000
K65.0 Acute peritonitis
0.759 0.241 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.758 0.242 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.757 0.243 0.000
K70.9 Alcoholic liver disease, unspecified
0.757 0.243 0.000
K76.8 Other specified diseases of liver
0.756 0.244 0.000
K86.1 Other chronic pancreatitis
0.755 0.245 0.000
R05 Cough
0.753 0.247 0.000
W19.2 School, other institution and public administrative area
0.752 0.247 0.000
S50-S59 Injuries to the elbow and forearm
0.752 0.248 0.000
M06.9 Rheumatoid arthritis, unspecified
0.750 0.250 0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum
0.750 0.250 0.000
H43-H45 Disorders of vitreous body and globe
0.749 0.251 0.000
F60-F69 Disorders of adult personality and behaviour
0.749 0.251 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.748 0.252 0.000
K72 Hepatic failure, not elsewhere classified
0.748 0.252 0.000
H53-H54 Visual disturbances and blindness
0.747 0.253 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.747 0.253 0.000
M65-M68 Disorders of synovium and tendon
0.747 0.253 0.000
N10 Acute tubulo-interstitial nephritis
0.745 0.255 0.000
K90-K93 Other diseases of the digestive system
0.744 0.256 0.000
K70.4 Alcoholic hepatic failure
0.744 0.256 0.000
N00-N08 Glomerular diseases
0.744 0.256 0.000
K57.1 Diverticular disease of small intestine without perforation or abscess
0.744 0.256 0.000
E83.4 Disorders of magnesium metabolism
0.743 0.257 0.000
X60-X84 Intentional self-harm
0.742 0.258 0.000
H30-H36 Disorders of choroid and retina
0.742 0.258 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.742 0.258 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.742 0.258 0.000
A41 Other septicaemia
0.740 0.260 0.000
F41 Other anxiety disorders
0.739 0.261 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.739 0.261 0.000
V10-V19 Pedal cyclist injured in transport accident
0.738 0.261 0.000
S02 Fracture of skull and facial bones
0.738 0.262 0.000
F10.3 Withdrawal state
0.737 0.263 0.000
S20-S29 Injuries to the thorax
0.736 0.264 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.735 0.265 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.735 0.265 0.000
Y84.2 Radiological procedure and radiotherapy
0.733 0.267 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.733 0.267 0.000
E87.7 Fluid overload
0.733 0.267 0.000
A80-A89 Viral infections of the central nervous system
0.733 0.267 0.000
N13.4 Hydroureter
0.732 0.268 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.732 0.268 0.000
F99-F99 Unspecified mental disorder
0.731 0.269 0.000
M11 Other crystal arthropathies
0.731 0.269 0.000
M25 Other joint disorders, not elsewhere classified
0.731 0.269 0.000
E87.2 Acidosis
0.731 0.269 0.000
S09 Other and unspecified injuries of head
0.731 0.269 0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension
0.730 0.270 0.000
N13.8 Other obstructive and reflux uropathy
0.728 0.272 0.000
K56.6 Other and unspecified intestinal obstruction
0.726 0.274 0.000
S79 Other and unspecified injuries of hip and thigh
0.725 0.275 0.000
N18.4 Chronic kidney disease, stage 4
0.724 0.276 0.000
T40.4 Other synthetic narcotics
0.723 0.277 0.000
K85.9 Acute pancreatitis, unspecified
0.723 0.277 0.000
K14 Diseases of tongue
0.722 0.278 0.000
F43 Reaction to severe stress, and adjustment disorders
0.721 0.279 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.720 0.280 0.000
H10-H13 Disorders of conjunctiva
0.719 0.280 0.000
E10-E14 Diabetes mellitus
0.719 0.281 0.000
W07 Fall involving chair
0.718 0.282 0.000
T39.1 4-Aminophenol derivatives
0.718 0.282 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.718 0.282 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.718 0.282 0.000
K82.8 Other specified diseases of gallbladder
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.717 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.717 0.283 0.000
Y10-Y34 Event of undetermined intent
0.717 0.283 0.000
Y00-Y09 Assault
0.717 0.283 0.000
X85-X99 Assault
0.717 0.283 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.717 0.283 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.717 0.283 0.000
X30-X39 Exposure to forces of nature
0.717 0.283 0.000
X20-X29 Contact with venomous animals and plants
0.717 0.283 0.000
X10-X19 Contact with heat and hot substances
0.717 0.283 0.000
X00-X09 Exposure to smoke, fire and flames
0.717 0.283 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.717 0.283 0.000
W75-W84 Other accidental threats to breathing
0.717 0.283 0.000
W65-W74 Accidental drowning and submersion
0.717 0.283 0.000
W50-W64 Exposure to animate mechanical forces
0.717 0.283 0.000
V98-V99 Other and unspecified transport accidents
0.717 0.283 0.000
V95-V97 Air and space transport accidents
0.717 0.283 0.000
V90-V94 Water transport accidents
0.717 0.283 0.000
V80-V89 Other land transport accidents
0.717 0.283 0.000
V70-V79 Bus occupant injured in transport accident
0.717 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.717 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.717 0.283 0.000
V40-V49 Car occupant injured in transport accident
0.717 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.717 0.283 0.000
V01-V09 Pedestrian injured in transport accident
0.717 0.283 0.000
T79-T79 Certain early complications of trauma
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
S10-S19 Injuries to the neck
0.716 0.284 0.000
I30-I52 Other forms of heart disease
0.716 0.284 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.715 0.284 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.715 0.284 0.000
Chapter XXII Codes for special purposes
0.715 0.285 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.715 0.285 0.000
F80-F89 Disorders of psychological development
0.715 0.285 0.000
F70-F79 Mental retardation
0.715 0.285 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.715 0.285 0.000
W18 Other fall on same level
0.714 0.286 0.000
W17 Other fall from one level to another
0.714 0.286 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.714 0.286 0.000
W15 Fall from cliff
0.714 0.286 0.000
W14 Fall from tree
0.714 0.286 0.000
W12 Fall on and from scaffolding
0.714 0.286 0.000
W11 Fall on and from ladder
0.714 0.286 0.000
W09 Fall involving playground equipment
0.714 0.286 0.000
W08 Fall involving other furniture
0.714 0.286 0.000
W05 Fall involving wheelchair
0.714 0.286 0.000
W04 Fall while being carried or supported by other persons
0.714 0.286 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.714 0.286 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.714 0.286 0.000
W00 Fall on same level involving ice and snow
0.714 0.286 0.000
K77 Liver disorders in diseases classified elsewhere
0.714 0.286 0.000
K73 Chronic hepatitis, not elsewhere classified
0.714 0.286 0.000
K71 Toxic liver disease
0.714 0.286 0.000
R13 Dysphagia
0.712 0.288 0.000
E40-E46 Malnutrition
0.711 0.289 0.000
E88 Other metabolic disorders
0.710 0.290 0.000
E85 Amyloidosis
0.710 0.290 0.000
E84 Cystic fibrosis
0.710 0.290 0.000
E79 Disorders of purine and pyrimidine metabolism
0.710 0.290 0.000
E77 Disorders of glycoprotein metabolism
0.710 0.290 0.000
E76 Disorders of glycosaminoglycan metabolism
0.710 0.290 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.710 0.290 0.000
E74 Other disorders of carbohydrate metabolism
0.710 0.290 0.000
E73 Lactose intolerance
0.710 0.290 0.000
E72 Other disorders of amino-acid metabolism
0.710 0.290 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.710 0.290 0.000
E70 Disorders of aromatic amino-acid metabolism
0.710 0.290 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.710 0.290 0.000
E87.4 Mixed disorder of acid-base balance
0.710 0.290 0.000
E87.3 Alkalosis
0.710 0.290 0.000
E87.0 Hyperosmolality and hypernatraemia
0.710 0.290 0.000
W20-W49 Exposure to inanimate mechanical forces
0.710 0.290 0.000
K13 Other diseases of lip and oral mucosa
0.709 0.291 0.000
B35-B49 Mycoses
0.709 0.291 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.708 0.292 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.708 0.292 0.000
N18.5 Chronic kidney disease, stage 5
0.707 0.293 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.707 0.293 0.000
N18.0 End-stage renal disease
0.707 0.293 0.000
W19.8 Other specified place
0.707 0.293 0.000
W19.5 Trade and service area
0.707 0.293 0.000
W19.0 Home
0.707 0.293 0.000
W19.7 Farm
0.707 0.293 0.000
W19.6 Industrial and construction area
0.707 0.293 0.000
W19.3 Sports and athletics area
0.707 0.293 0.000
W19.1 Residential institution
0.707 0.293 0.000
M50-M54 Other dorsopathies
0.706 0.294 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.706 0.294 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.706 0.294 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.706 0.294 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.706 0.294 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.706 0.294 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.706 0.294 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.706 0.294 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.706 0.294 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.706 0.294 0.000
T36 Poisoning by systemic antibiotics
0.706 0.294 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.706 0.294 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.706 0.294 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.706 0.294 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.706 0.294 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.706 0.294 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.706 0.294 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.706 0.294 0.000
F11 Mental and behavioural disorders due to use of opioids
0.706 0.294 0.000
Y57 Other and unspecified drugs and medicaments
0.705 0.295 0.000
T40.2 Other opioids
0.704 0.296 0.000
M05 Seropositive rheumatoid arthritis
0.703 0.297 0.000
F10.9 Unspecified mental and behavioural disorder
0.703 0.297 0.000
F10.8 Other mental and behavioural disorders
0.703 0.297 0.000
F10.7 Residual and late-onset psychotic disorder
0.703 0.297 0.000
F10.6 Amnesic syndrome
0.703 0.297 0.000
F10.5 Psychotic disorder
0.703 0.297 0.000
F10.4 Withdrawal state with delirium
0.703 0.297 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.703 0.297 0.000
V20-V29 Motorcycle rider injured in transport accident
0.703 0.297 0.000
K75.8 Other specified inflammatory liver diseases
0.702 0.298 0.000
K56.7 Ileus, unspecified
0.701 0.299 0.000
T39.0 Salicylates
0.700 0.300 0.000
K86.2 Cyst of pancreas
0.699 0.301 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.699 0.301 0.000
S90-S99 Injuries to the ankle and foot
0.698 0.301 0.000
K52.3 Indeterminate colitis
0.697 0.303 0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.697 0.303 0.000
K52.0 Gastro-enteritis and colitis due to radiation
0.697 0.303 0.000
R07 Pain in throat and chest
0.697 0.303 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.695 0.304 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.694 0.306 0.000
E83.1 Disorders of iron metabolism
0.692 0.307 0.000
A41.9 Septicaemia, unspecified
0.692 0.308 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.692 0.308 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.692 0.308 0.000
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess
0.691 0.309 0.000
K57.5 Diverticular disease of both small and large intestine without perforation or abscess
0.691 0.309 0.000
K57.4 Diverticular disease of both small and large intestine with perforation and abscess
0.691 0.309 0.000
K57.0 Diverticular disease of small intestine with perforation and abscess
0.691 0.309 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.690 0.310 0.000
W06.0 Home
0.690 0.310 0.000
F45 Somatoform disorders
0.690 0.310 0.000
S89 Other and unspecified injuries of lower leg
0.689 0.311 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.689 0.311 0.000
M40-M43 Deforming dorsopathies
0.689 0.311 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.687 0.313 0.000
N15 Other renal tubulo-interstitial diseases
0.687 0.313 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.687 0.313 0.000
N11 Chronic tubulo-interstitial nephritis
0.687 0.313 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.686 0.314 0.000
H57 Other disorders of eye and adnexa
0.686 0.314 0.000
B95-B98 Bacterial, viral and other infectious agents
0.686 0.314 0.000
K08 Other disorders of teeth and supporting structures
0.686 0.314 0.000
Y42.5 Other oestrogens and progestogens
0.685 0.314 0.000
K51.8 Other ulcerative colitis
0.685 0.315 0.000
R19.6 Halitosis
0.685 0.315 0.000
R19.3 Abdominal rigidity
0.685 0.315 0.000
R19.2 Visible peristalsis
0.685 0.315 0.000
R19.1 Abnormal bowel sounds
0.685 0.315 0.000
S00.9 Superficial injury of head, part unspecified
0.685 0.315 0.000
T66-T78 Other and unspecified effects of external causes
0.684 0.316 0.000
B99-B99 Other infectious diseases
0.683 0.317 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.683 0.317 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.683 0.317 0.000
B65-B83 Helminthiases
0.683 0.317 0.000
B50-B64 Protozoal diseases
0.683 0.317 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.683 0.317 0.000
B15-B19 Viral hepatitis
0.683 0.317 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.683 0.317 0.000
A75-A79 Rickettsioses
0.683 0.317 0.000
A70-A74 Other diseases caused by chlamydiae
0.683 0.317 0.000
A65-A69 Other spirochaetal diseases
0.683 0.317 0.000
A20-A28 Certain zoonotic bacterial diseases
0.683 0.317 0.000
A15-A19 Tuberculosis
0.683 0.317 0.000
S06.5 Traumatic subdural haemorrhage
0.682 0.318 0.000
D60-D64 Aplastic and other anaemias
0.682 0.318 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.681 0.319 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.681 0.319 0.000
K59 Other functional intestinal disorders
0.681 0.319 0.000
S72 Fracture of femur
0.679 0.320 0.000
F40 Phobic anxiety disorders
0.679 0.321 0.000
Y52 Agents primarily affecting the cardiovascular system
0.679 0.321 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.677 0.323 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.676 0.324 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.675 0.325 0.000
M70-M79 Other soft tissue disorders
0.675 0.325 0.000
M91-M94 Chondropathies
0.674 0.325 0.000
M60-M63 Disorders of muscles
0.674 0.325 0.000
M00-M03 Infectious arthropathies
0.674 0.325 0.000
H01 Other inflammation of eyelid
0.673 0.327 0.000
K85.1 Biliary acute pancreatitis
0.673 0.327 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.673 0.327 0.000
R49 Voice disturbances
0.672 0.328 0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified
0.672 0.328 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.672 0.328 0.000
M10 Gout
0.672 0.328 0.000
D68 Other coagulation defects
0.672 0.328 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.671 0.329 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.671 0.329 0.000
B25-B34 Other viral diseases
0.671 0.329 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.670 0.330 0.000
A49 Bacterial infection of unspecified site
0.669 0.331 0.000
M25.4 Effusion of joint
0.669 0.331 0.000
K51.4 Pseudopolyposis of colon
0.669 0.331 0.000
R00 Abnormalities of heart beat
0.669 0.331 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.666 0.334 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.666 0.334 0.000
N13.6 Pyonephrosis
0.666 0.334 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.666 0.334 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.666 0.334 0.000
K55.2 Angiodysplasia of colon
0.665 0.335 0.000
K76.7 Hepatorenal syndrome
0.663 0.337 0.000
K76.5 Hepatic veno-occlusive disease
0.663 0.337 0.000
K76.4 Peliosis hepatis
0.663 0.337 0.000
K76.3 Infarction of liver
0.663 0.337 0.000
K76.2 Central haemorrhagic necrosis of liver
0.663 0.337 0.000
K76.1 Chronic passive congestion of liver
0.663 0.337 0.000
M25.5 Pain in joint
0.662 0.338 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.662 0.338 0.000
M90 Osteopathies in diseases classified elsewhere
0.662 0.338 0.000
N28.8 Other specified disorders of kidney and ureter
0.661 0.339 0.000
K80 Cholelithiasis
0.660 0.340 0.000
K70.2 Alcoholic fibrosis and sclerosis of liver
0.658 0.342 0.000
K70.1 Alcoholic hepatitis
0.658 0.342 0.000
K70.0 Alcoholic fatty liver
0.658 0.342 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.658 0.342 0.000
N20-N23 Urolithiasis
0.658 0.342 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.658 0.342 0.000
T43.9 Psychotropic drug, unspecified
0.657 0.343 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.657 0.343 0.000
T43.6 Psychostimulants with abuse potential
0.657 0.343 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.657 0.343 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.657 0.343 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.657 0.343 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.657 0.343 0.000
F20 Schizophrenia
0.656 0.343 0.000
E20-E35 Disorders of other endocrine glands
0.656 0.344 0.000
S08 Traumatic amputation of part of head
0.654 0.346 0.000
S07 Crushing injury of head
0.654 0.346 0.000
S05 Injury of eye and orbit
0.654 0.346 0.000
S04 Injury of cranial nerves
0.654 0.346 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.654 0.346 0.000
S70 Superficial injury of hip and thigh
0.653 0.347 0.000
E86 Volume depletion
0.652 0.348 0.000
M07 Psoriatic and enteropathic arthropathies
0.651 0.349 0.000
L20-L30 Dermatitis and eczema
0.650 0.350 0.000
K12 Stomatitis and related lesions
0.650 0.350 0.000
K74.5 Biliary cirrhosis, unspecified
0.649 0.351 0.000
K74.4 Secondary biliary cirrhosis
0.649 0.351 0.000
K74.3 Primary biliary cirrhosis
0.649 0.351 0.000
K74.2 Hepatic fibrosis with hepatic sclerosis
0.649 0.351 0.000
K74.1 Hepatic sclerosis
0.649 0.351 0.000
K74.0 Hepatic fibrosis
0.649 0.351 0.000
H35 Other retinal disorders
0.649 0.351 0.000
K52.8 Other specified non-infective gastro-enteritis and colitis
0.648 0.352 0.000
R16.0 Hepatomegaly, not elsewhere classified
0.647 0.352 0.000
W13.9 Unspecified place
0.647 0.353 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.647 0.353 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.646 0.354 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.646 0.354 0.000
E83.8 Other disorders of mineral metabolism
0.646 0.354 0.000
E83.3 Disorders of phosphorus metabolism
0.646 0.354 0.000
E83.2 Disorders of zinc metabolism
0.646 0.354 0.000
E83.0 Disorders of copper metabolism
0.646 0.354 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.644 0.355 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.644 0.355 0.000
Y98 Lifestyle-related condition
0.644 0.355 0.000
Y97 Environmental-pollution-related condition
0.644 0.355 0.000
Y96 Work-related condition
0.644 0.355 0.000
K05 Gingivitis and periodontal diseases
0.644 0.356 0.000
K61 Abscess of anal and rectal regions
0.643 0.356 0.000
W02.9 Unspecified place
0.643 0.357 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.642 0.358 0.000
I60-I69 Cerebrovascular diseases
0.642 0.358 0.000
F48 Other neurotic disorders
0.642 0.358 0.000
F44 Dissociative [conversion] disorders
0.642 0.358 0.000
F42 Obsessive-compulsive disorder
0.642 0.358 0.000
T92 Sequelae of injuries of upper limb
0.642 0.358 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.641 0.359 0.000
K65.9 Peritonitis, unspecified
0.640 0.360 0.000
N18.8 Other chronic renal failure
0.639 0.360 0.000
N18.2 Chronic kidney disease, stage 2
0.639 0.360 0.000
N18.1 Chronic kidney disease, stage 1
0.639 0.360 0.000
R01 Cardiac murmurs and other cardiac sounds
0.639 0.361 0.000
R10 Abdominal and pelvic pain
0.638 0.362 0.000
K75.9 Inflammatory liver disease, unspecified
0.637 0.363 0.000
I38 Endocarditis, valve unspecified
0.637 0.363 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.637 0.363 0.000
K56.5 Intestinal adhesions [bands] with obstruction
0.637 0.363 0.000
W10.8 Other specified place
0.636 0.364 0.000
H05 Disorders of orbit
0.636 0.364 0.000
R07.4 Chest pain, unspecified
0.635 0.365 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.635 0.365 0.000
T87 Complications peculiar to reattachment and amputation
0.635 0.365 0.000
T86 Failure and rejection of transplanted organs and tissues
0.635 0.365 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.634 0.366 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.634 0.366 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.634 0.366 0.000
R00.1 Bradycardia, unspecified
0.633 0.367 0.000
N17.8 Other acute renal failure
0.633 0.367 0.000
N17.2 Acute renal failure with medullary necrosis
0.633 0.367 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.633 0.367 0.000
N17.0 Acute renal failure with tubular necrosis
0.633 0.367 0.000
N93 Other abnormal uterine and vaginal bleeding
0.633 0.367 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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