TreeWAS – Variant ID: rs79300279

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
S00-S09 Injuries to the head	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
S02 Fracture of skull and facial bones	1.000	0.000
Chapter XX External causes of morbidity and mortality	1.000	0.000
# Top node	0.999	0.001
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.997	0.003
S02.4 Fracture of malar and maxillary bones	0.996	0.004
S02.40 Fracture of malar and maxillary bones (closed)	0.993	0.007
Chapter X Diseases of the respiratory system	0.987	0.013
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.982	0.018
S60-S69 Injuries to the wrist and hand	0.974	0.026
J09-J18 Influenza and pneumonia	0.965	0.035
S20-S29 Injuries to the thorax	0.960	0.040
S66 Injury of muscle and tendon at wrist and hand level	0.955	0.045
S00 Superficial injury of head	0.952	0.048
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.949	0.051
Chapter XV Pregnancy, childbirth and the puerperium	0.946	0.054
M86-M90 Other osteopathies	0.943	0.057
S90-S99 Injuries to the ankle and foot	0.929	0.071
Y52 Agents primarily affecting the cardiovascular system	0.925	0.075
M40-M43 Deforming dorsopathies	0.923	0.077
S06 Intracranial injury	0.922	0.078
Y44 Agents primarily affecting blood constituents	0.919	0.081
Y40 Systemic antibiotics	0.916	0.084
J00-J06 Acute upper respiratory infections	0.915	0.085
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.915	0.085
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.913	0.087
J90-J94 Other diseases of pleura	0.907	0.093
S02.2 Fracture of nasal bones	0.901	0.099
S22 Fracture of rib(s), sternum and thoracic spine	0.900	0.100
J17 Pneumonia in diseases classified elsewhere	0.896	0.104
Y52.4 Angiotensin-converting-enzyme inhibitors	0.893	0.107
Y57 Other and unspecified drugs and medicaments	0.893	0.107
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.893	0.107
J03 Acute tonsillitis	0.883	0.117
O85-O92 Complications predominantly related to the puerperium	0.880	0.120
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.875	0.125
Y60-Y69 Misadventures to patients during surgical and medical care	0.868	0.132
S02.8 Fractures of other skull and facial bones	0.867	0.133
M90 Osteopathies in diseases classified elsewhere	0.866	0.134
S69 Other and unspecified injuries of wrist and hand	0.865	0.135
M00-M03 Infectious arthropathies	0.862	0.138
J86 Pyothorax	0.860	0.140
J03.9 Acute tonsillitis, unspecified	0.860	0.140
O00-O08 Pregnancy with abortive outcome	0.859	0.141
S01 Open wound of head	0.859	0.141
J10 Influenza due to identified influenza virus	0.855	0.145
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.851	0.149
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.848	0.152
S00.7 Multiple superficial injuries of head	0.848	0.152
S01.1 Open wound of eyelid and periocular area	0.847	0.153
M43 Other deforming dorsopathies	0.847	0.153
J91 Pleural effusion in conditions classified elsewhere	0.841	0.159
Y40.9 Systemic antibiotic, unspecified	0.840	0.160
S00.9 Superficial injury of head, part unspecified	0.839	0.161
S92 Fracture of foot, except ankle	0.838	0.162
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.836	0.164
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.834	0.166
S00.0 Superficial injury of scalp	0.834	0.166
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.833	0.166
Y44.2 Anticoagulants	0.833	0.167
M60-M63 Disorders of muscles	0.830	0.170
S02.20 Fracture of nasal bones (closed)	0.830	0.170
Chapter I Certain infectious and parasitic diseases	0.829	0.171
S20 Superficial injury of thorax	0.828	0.172
J86.9 Pyothorax without fistula	0.822	0.178
W20-W49 Exposure to inanimate mechanical forces	0.821	0.179
Y57.9 Drug or medicament, unspecified	0.818	0.182
Y84.2 Radiological procedure and radiotherapy	0.817	0.183
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.817	0.183
M89 Other disorders of bone	0.815	0.185
S67 Crushing injury of wrist and hand	0.815	0.185
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.815	0.185
S10-S19 Injuries to the neck	0.814	0.186
Y40.1 Cefalosporins and other -lactam antibiotics	0.813	0.187
Chapter V Mental and behavioural disorders	0.812	0.188
M90.7 Fracture of bone in neoplastic disease	0.811	0.189
X40-X49 Accidental poisoning by and exposure to noxious substances	0.810	0.190
S02.1 Fracture of base of skull	0.809	0.191
D50-D53 Nutritional anaemias	0.808	0.192
X58-X59 Accidental exposure to other and unspecified factors	0.808	0.192
Y84.0 Cardiac catheterisation	0.808	0.192
J17.2 Pneumonia in mycoses	0.804	0.196
V20-V29 Motorcycle rider injured in transport accident	0.803	0.197
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.802	0.198
O00 Ectopic pregnancy	0.802	0.198
M05-M14 Inflammatory polyarthropathies	0.800	0.200
Chapter XXII Codes for special purposes	0.799	0.201
M43.1 Spondylolisthesis	0.795	0.205
S02.0 Fracture of vault of skull	0.794	0.206
S02.5 Fracture of tooth	0.794	0.206
M65-M68 Disorders of synovium and tendon	0.793	0.207
O20-O29 Other maternal disorders predominantly related to pregnancy	0.793	0.207
S02.3 Fracture of orbital floor	0.791	0.209
S22.2 Fracture of sternum	0.790	0.210
S50-S59 Injuries to the elbow and forearm	0.790	0.210
S69.9 Unspecified injury of wrist and hand	0.787	0.213
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.787	0.213
M50-M54 Other dorsopathies	0.787	0.213
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.782	0.218
Y00-Y09 Assault	0.781	0.219
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.780	0.220
J93 Pneumothorax	0.779	0.221
J14 Pneumonia due to Haemophilus influenzae	0.778	0.222
J10.1 Influenza with other respiratory manifestations, influenza virus identified	0.775	0.225
M00 Pyogenic arthritis	0.775	0.225
S02.9 Fracture of skull and facial bones, part unspecified	0.774	0.226
M06 Other rheumatoid arthritis	0.774	0.226
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.773	0.227
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.773	0.227
S02.80 Fractures of other skull and facial bones (closed)	0.773	0.227
Y41 Other systemic anti-infectives and antiparasitics	0.772	0.228
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.772	0.228
M45-M49 Spondylopathies	0.770	0.230
M43.16 Spondylolisthesis (Lumbar region)	0.770	0.230
D52 Folate deficiency anaemia	0.769	0.231
S06.2 Diffuse brain injury	0.768	0.232
Y83.6 Removal of other organ (partial) (total)	0.768	0.232
S27 Injury of other and unspecified intrathoracic organs	0.765	0.235
T20-T25 Burns and corrosions of external body surface, specified by site	0.764	0.236
X60-X84 Intentional self-harm	0.764	0.236
S22.3 Fracture of rib	0.763	0.237
V98-V99 Other and unspecified transport accidents	0.762	0.238
S02.7 Multiple fractures involving skull and facial bones	0.762	0.238
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.762	0.238
J17.0 Pneumonia in bacterial diseases classified elsewhere	0.761	0.239
O92 Other disorders of breast and lactation associated with childbirth	0.756	0.243
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.755	0.245
S06.6 Traumatic subarachnoid haemorrhage	0.753	0.247
M06.9 Rheumatoid arthritis, unspecified	0.751	0.249
Y44.5 Thrombolytic drugs	0.750	0.250
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.749	0.251
Y84.6 Urinary catheterisation	0.749	0.251
Y49 Psychotropic drugs, not elsewhere classified	0.748	0.252
Y46 Antiepileptics and anti-Parkinsonism drugs	0.747	0.253
S91 Open wound of ankle and foot	0.746	0.254
T00-T07 Injuries involving multiple body regions	0.746	0.254
O86 Other puerperal infections	0.744	0.256
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.743	0.257
S00.5 Superficial injury of lip and oral cavity	0.742	0.258
S70-S79 Injuries to the hip and thigh	0.741	0.259
D52.9 Folate deficiency anaemia, unspecified	0.741	0.259
S92.0 Fracture of calcaneus	0.740	0.259
J15 Bacterial pneumonia, not elsewhere classified	0.740	0.260
O94-O99 Other obstetric conditions, not elsewhere classified	0.738	0.262
S22.0 Fracture of thoracic vertebra	0.736	0.264
J60-J70 Lung diseases due to external agents	0.736	0.264
S05 Injury of eye and orbit	0.735	0.265
T90 Sequelae of injuries of head	0.733	0.267
M41 Scoliosis	0.732	0.268
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.730	0.270
S68 Traumatic amputation of wrist and hand	0.729	0.271
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.728	0.272
X20-X29 Contact with venomous animals and plants	0.728	0.272
O00.1 Tubal pregnancy	0.725	0.275
M86 Osteomyelitis	0.723	0.277
F20 Schizophrenia	0.723	0.277
J13 Pneumonia due to Streptococcus pneumoniae	0.721	0.279
M40 Kyphosis and lordosis	0.720	0.280
J11 Influenza, virus not identified	0.717	0.282
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.717	0.283
S08 Traumatic amputation of part of head	0.717	0.283
S07 Crushing injury of head	0.717	0.283
S04 Injury of cranial nerves	0.717	0.283
S03 Dislocation, sprain and strain of joints and ligaments of head	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
Y35-Y36 Legal intervention and operations of war	0.717	0.283
Y10-Y34 Event of undetermined intent	0.717	0.283
X85-X99 Assault	0.717	0.283
X30-X39 Exposure to forces of nature	0.717	0.283
X10-X19 Contact with heat and hot substances	0.717	0.283
X00-X09 Exposure to smoke, fire and flames	0.717	0.283
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.717	0.283
W75-W84 Other accidental threats to breathing	0.717	0.283
W65-W74 Accidental drowning and submersion	0.717	0.283
V95-V97 Air and space transport accidents	0.717	0.283
V90-V94 Water transport accidents	0.717	0.283
V70-V79 Bus occupant injured in transport accident	0.717	0.283
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.717	0.283
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.717	0.283
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.717	0.283
V01-V09 Pedestrian injured in transport accident	0.717	0.283
O46 Antepartum haemorrhage, not elsewhere classified	0.717	0.283
D69 Purpura and other haemorrhagic conditions	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.716	0.284
S90 Superficial injury of ankle and foot	0.716	0.284
W29 Contact with other powered hand tools and household machinery	0.716	0.284
Y59 Other and unspecified vaccines and biological substances	0.715	0.285
Y58 Bacterial vaccines	0.715	0.285
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.715	0.285
Y53 Agents primarily affecting the gastro-intestinal system	0.715	0.285
Y50 Central nervous system stimulants, not elsewhere classified	0.715	0.285
Y48 Anaesthetics and therapeutic gases	0.715	0.285
Y47 Sedatives, hypnotics and antianxiety drugs	0.715	0.285
S00.2 Other superficial injuries of eyelid and periocular area	0.715	0.285
S02.6 Fracture of mandible	0.714	0.285
Y40.8 Other systemic antibiotics	0.714	0.286
S02.41 Fracture of malar and maxillary bones (open)	0.714	0.286
M00.9 Pyogenic arthritis, unspecified	0.713	0.287
S06.5 Traumatic subdural haemorrhage	0.713	0.287
A30-A49 Other bacterial diseases	0.713	0.287
V40-V49 Car occupant injured in transport accident	0.712	0.288
Q50-Q56 Congenital malformations of genital organs	0.712	0.288
S22.20 Fracture of sternum (closed)	0.712	0.288
W00-W19 Falls	0.709	0.291
J90 Pleural effusion, not elsewhere classified	0.708	0.292
M90.72 Fracture of bone in neoplastic disease (Upper arm)	0.707	0.293
W50-W64 Exposure to animate mechanical forces	0.705	0.295
Y60.0 During surgical operation	0.705	0.295
Y57.8 Other drugs and medicaments	0.704	0.296
F25 Schizoaffective disorders	0.702	0.298
S67.0 Crushing injury of thumb and other finger(s)	0.702	0.298
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.701	0.299
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.701	0.299
O90 Complications of the puerperium, not elsewhere classified	0.700	0.300
S06.0 Concussion	0.699	0.301
T66-T78 Other and unspecified effects of external causes	0.698	0.302
S65 Injury of blood vessels at wrist and hand level	0.698	0.302
X50-X57 Overexertion, travel and privation	0.698	0.302
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.698	0.302
S20.1 Other and unspecified superficial injuries of breast	0.698	0.302
Y76 Obstetric and gynaecological devices associated with adverse incidents	0.697	0.303
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.696	0.304
S96 Injury of muscle and tendon at ankle and foot level	0.695	0.305
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.693	0.307
M45 Ankylosing spondylitis	0.693	0.307
S00.3 Superficial injury of nose	0.693	0.307
S01.4 Open wound of cheek and temporomandibular area	0.693	0.307
Q80-Q89 Other congenital malformations	0.692	0.308
S92.5 Fracture of other toe	0.692	0.308
M60 Myositis	0.692	0.308
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.692	0.308
J12 Viral pneumonia, not elsewhere classified	0.692	0.308
J09 Influenza due to certain identified influenza virus	0.692	0.308
V80-V89 Other land transport accidents	0.691	0.309
S06.8 Other intracranial injuries	0.689	0.310
S99 Other and unspecified injuries of ankle and foot	0.689	0.311
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.688	0.311
S26 Injury of heart	0.688	0.311
S25 Injury of blood vessels of thorax	0.688	0.311
S24 Injury of nerves and spinal cord at thorax level	0.688	0.311
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.688	0.311
S21 Open wound of thorax	0.688	0.311
S01.2 Open wound of nose	0.687	0.313
A00-A09 Intestinal infectious diseases	0.686	0.314
Y85 Sequelae of transport accidents	0.686	0.314
M89.8 Other specified disorders of bone	0.686	0.314
J04 Acute laryngitis and tracheitis	0.686	0.314
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.685	0.315
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.685	0.315
V10-V19 Pedal cyclist injured in transport accident	0.685	0.315
M87 Osteonecrosis	0.684	0.315
S00.4 Superficial injury of ear	0.683	0.317
M88 Paget's disease of bone [osteitis deformans]	0.682	0.318
O04 Medical abortion	0.682	0.318
Q60-Q64 Congenital malformations of the urinary system	0.680	0.320
J01 Acute sinusitis	0.680	0.320
O46.9 Antepartum haemorrhage, unspecified	0.680	0.320
S06.3 Focal brain injury	0.680	0.320
M66 Spontaneous rupture of synovium and tendon	0.679	0.321
O00.9 Ectopic pregnancy, unspecified	0.679	0.321
Y83.3 Surgical operation with formation of external stoma	0.678	0.322
J93.1 Other spontaneous pneumothorax	0.676	0.324
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.675	0.324
B25-B34 Other viral diseases	0.675	0.325
S02.10 Fracture of base of skull (closed)	0.673	0.327
S80-S89 Injuries to the knee and lower leg	0.672	0.328
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.672	0.328
Y84.1 Kidney dialysis	0.670	0.329
S92.00 Fracture of calcaneus (closed)	0.670	0.330
S20.3 Other superficial injuries of front wall of thorax	0.668	0.332
W21 Striking against or struck by sports equipment	0.668	0.332
S98 Traumatic amputation of ankle and foot	0.666	0.334
S97 Crushing injury of ankle and foot	0.666	0.334
S95 Injury of blood vessels at ankle and foot level	0.666	0.334
S94 Injury of nerves at ankle and foot level	0.666	0.334
S22.30 Fracture of rib (closed)	0.665	0.335
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.664	0.336
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.663	0.337
Y52.8 Antivaricose drugs, including sclerosing agents	0.663	0.337
Y52.7 Peripheral vasodilators	0.663	0.337
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.663	0.337
M89.0 Algoneurodystrophy	0.663	0.337
D51 Vitamin B12 deficiency anaemia	0.662	0.338
T15-T19 Effects of foreign body entering through natural orifice	0.662	0.338
M42 Spinal osteochondrosis	0.661	0.338
V23 Motorcycle rider injured in collision with car, pick-up truck or van	0.661	0.338
S06.9 Intracranial injury, unspecified	0.661	0.339
S06.7 Intracranial injury with prolonged coma	0.661	0.339
S06.4 Epidural haemorrhage	0.661	0.339
S06.1 Traumatic cerebral oedema	0.661	0.339
J95-J99 Other diseases of the respiratory system	0.660	0.340
Y44.9 Other and unspecified agents affecting blood constituents	0.659	0.341
Y44.7 Plasma substitutes	0.659	0.341
Y44.6 Natural blood and blood products	0.659	0.341
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.659	0.341
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.659	0.341
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.659	0.341
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.659	0.341
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.659	0.341
S22.5 Flail chest	0.658	0.342
S06.20 Diffuse brain injury (without open intracranial wound)	0.658	0.342
O34 Maternal care for known or suspected abnormality of pelvic organs	0.657	0.343
Y40.7 Antifungal antibiotics, systemically used	0.657	0.343
Y40.6 Rifamycins	0.657	0.343
Y40.5 Aminoglycosides	0.657	0.343
Y40.4 Tetracyclines	0.657	0.343
Y40.2 Chloramphenicol group	0.657	0.343
S36 Injury of intra-abdominal organs	0.656	0.344
M00.96 Pyogenic arthritis, unspecified (Lower leg)	0.656	0.344
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.655	0.344
O86.1 Other infection of genital tract following delivery	0.655	0.345
J85 Abscess of lung and mediastinum	0.655	0.345
F50 Eating disorders	0.655	0.345
S64 Injury of nerves at wrist and hand level	0.654	0.345
F20.9 Schizophrenia, unspecified	0.654	0.346
T91 Sequelae of injuries of neck and trunk	0.653	0.347
S56 Injury of muscle and tendon at forearm level	0.651	0.349
O48 Prolonged pregnancy	0.651	0.349
J05 Acute obstructive laryngitis [croup] and epiglottitis	0.650	0.350
W27 Contact with nonpowered hand tool	0.649	0.351
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.647	0.352
S02.00 Fracture of vault of skull (closed)	0.647	0.353
M91-M94 Chondropathies	0.646	0.354
S02.21 Fracture of nasal bones (open)	0.646	0.354
S02.50 Fracture of tooth (closed)	0.646	0.354
S22.9 Fracture of bony thorax, part unspecified	0.645	0.355
S22.8 Fracture of other parts of bony thorax	0.645	0.355
M62 Other disorders of muscle	0.645	0.355
S30 Superficial injury of abdomen, lower back and pelvis	0.645	0.355
S61 Open wound of wrist and hand	0.644	0.355
O87 Venous complications in the puerperium	0.643	0.357
J17.8 Pneumonia in other diseases classified elsewhere	0.643	0.357
J17.3 Pneumonia in parasitic diseases	0.643	0.357
J17.1 Pneumonia in viral diseases classified elsewhere	0.643	0.357
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.642	0.357
S02.30 Fracture of orbital floor (closed)	0.642	0.358
S09 Other and unspecified injuries of head	0.641	0.359
B99-B99 Other infectious diseases	0.640	0.360
W29.9 Unspecified place	0.640	0.360
Y57.7 Vitamins, not elsewhere classified	0.640	0.360
Y57.6 Other diagnostic agents	0.640	0.360
Y57.4 Pharmaceutical excipients	0.640	0.360
Y57.3 Alcohol deterrents	0.640	0.360
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.640	0.360
Y57.1 Lipotropic drugs	0.640	0.360
Y57.0 Appetite depressants [anorectics]	0.640	0.360
Y84.9 Medical procedure, unspecified	0.640	0.360
Y84.7 Blood-sampling	0.640	0.360
Y84.5 Insertion of gastric or duodenal sound	0.640	0.360
Y84.3 Shock therapy	0.640	0.360
X59 Exposure to unspecified factor	0.639	0.361
O21 Excessive vomiting in pregnancy	0.638	0.362
O80-O84 Delivery	0.638	0.362
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified	0.636	0.364
S22.1 Multiple fractures of thoracic spine	0.635	0.365
O92.2 Other and unspecified disorders of breast associated with childbirth	0.635	0.365
O28 Abnormal findings on antenatal screening of mother	0.634	0.366
O03 Spontaneous abortion	0.634	0.366
J03.8 Acute tonsillitis due to other specified organisms	0.633	0.367
J03.0 Streptococcal tonsillitis	0.633	0.367
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.632	0.368
T90.5 Sequelae of intracranial injury	0.632	0.368
Y00 Assault by blunt object	0.632	0.368
M53 Other dorsopathies, not elsewhere classified	0.632	0.368
O91 Infections of breast associated with childbirth	0.631	0.369
O89 Complications of anaesthesia during the puerperium	0.631	0.369
O88 Obstetric embolism	0.631	0.369
O85 Puerperal sepsis	0.631	0.369
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances	0.631	0.369
J02 Acute pharyngitis	0.630	0.370
Y79 Orthopaedic devices associated with adverse incidents	0.630	0.370
F25.9 Schizoaffective disorder, unspecified	0.630	0.370
S31 Open wound of abdomen, lower back and pelvis	0.628	0.372
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.628	0.372
Q35-Q37 Cleft lip and cleft palate	0.628	0.372
Q30-Q34 Congenital malformations of the respiratory system	0.628	0.372
T93 Sequelae of injuries of lower limb	0.628	0.372
X69 Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances	0.627	0.373
O32 Maternal care for known or suspected malpresentation of foetus	0.626	0.374
S12 Fracture of neck	0.625	0.375
D69.3 Idiopathic thrombocytopenic purpura	0.623	0.377
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.623	0.377
F40-F48 Neurotic, stress-related and somatoform disorders	0.623	0.377
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.623	0.377
Y40.3 Macrolides	0.623	0.377
X58 Exposure to other specified factors	0.622	0.378
Y65 Other misadventures during surgical and medical care	0.622	0.378
Y64 Contaminated medical or biological substances	0.622	0.378
Y63 Failure in dosage during surgical and medical care	0.622	0.378
Y62 Failure of sterile precautions during surgical and medical care	0.622	0.378
Y61 Foreign object accidentally left in body during surgical and medical care	0.622	0.378
Y69 Unspecified misadventure during surgical and medical care	0.622	0.378
Y66 Nonadministration of surgical and medical care	0.622	0.378
Q66 Congenital deformities of feet	0.622	0.378
S02.81 Fractures of other skull and facial bones (open)	0.622	0.378
W23 Caught, crushed, jammed or pinched in or between objects	0.621	0.379
M90.8 Osteopathy in other diseases classified elsewhere	0.621	0.379
M90.6 Osteitis deformans in neoplastic disease	0.621	0.379
M90.5 Osteonecrosis in other diseases classified elsewhere	0.621	0.379
M90.4 Osteonecrosis due to heamoglobinopathy	0.621	0.379
M90.3 Osteonecrosis in caisson disease	0.621	0.379
M90.2 Osteopathy in other infectious diseases classified elsewhere	0.621	0.379
M90.1 Periostitis in other infectious diseases classified elsewhere	0.621	0.379
M90.0 Tuberculosis of bone	0.621	0.379
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.620	0.379
S69.8 Other specified injuries of wrist and hand	0.620	0.380
S69.7 Multiple injuries of wrist and hand	0.620	0.380
Y52.1 Calcium-channel blockers	0.620	0.380
J93.9 Pneumothorax, unspecified	0.620	0.380
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.620	0.380
J18 Pneumonia, organism unspecified	0.620	0.380
Y86 Sequelae of other accidents	0.619	0.381
S22.00 Fracture of thoracic vertebra (closed)	0.619	0.381
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.618	0.382
F20.0 Paranoid schizophrenia	0.618	0.382
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.618	0.382
M02 Reactive arthropathies	0.618	0.382
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.618	0.382
T94 Sequelae of injuries involving multiple and unspecified body regions	0.618	0.382
S27.3 Other injuries of lung	0.617	0.383
S40-S49 Injuries to the shoulder and upper arm	0.617	0.383
J86.0 Pyothorax with fistula	0.617	0.383
S70 Superficial injury of hip and thigh	0.616	0.384
O08 Complications following abortion and ectopic and molar pregnancy	0.616	0.384
O07 Failed attempted abortion	0.616	0.384
O06 Unspecified abortion	0.616	0.384
O05 Other abortion	0.616	0.384
O01 Hydatidiform mole	0.616	0.384
J67 Hypersensitivity pneumonitis due to organic dust	0.615	0.385
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.614	0.386
U51 Admission status on psychiatric patients	0.614	0.386
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.613	0.387
J10.8 Influenza with other manifestations, influenza virus identified	0.613	0.387
J10.0 Influenza with pneumonia, influenza virus identified	0.613	0.387
W20 Struck by thrown, projected or falling object	0.613	0.387
Y51 Drugs primarily affecting the autonomic nervous system	0.612	0.387
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.612	0.388
S66.8 Injury of other muscles and tendons at wrist and hand level	0.612	0.388
Q60 Renal agenesis and other reduction defects of kidney	0.611	0.388
S81 Open wound of lower leg	0.611	0.388
Y84.4 Aspiration of fluid	0.611	0.389
Y42.7 Androgens and anabolic congeners	0.611	0.389
F50.0 Anorexia nervosa	0.611	0.389
Y54.3 Benzothiadiazine derivatives	0.611	0.389
S01.3 Open wound of ear	0.610	0.390
M45.X9 Ankylosing spondylitis (Site unspecified)	0.610	0.390
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.608	0.392
D68 Other coagulation defects	0.608	0.392
M43.9 Deforming dorsopathy, unspecified	0.607	0.393
M43.8 Other specified deforming dorsopathies	0.607	0.393
M43.6 Torticollis	0.607	0.393
M43.5 Other recurrent vertebral subluxation	0.607	0.393
M43.4 Other recurrent atlantoaxial subluxation	0.607	0.393
M43.3 Recurrent atlantoaxial subluxation with myelopathy	0.607	0.393
M43.2 Other fusion of spine	0.607	0.393
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.607	0.393
S11 Open wound of neck	0.607	0.393
Y41.0 Sulphonamides	0.606	0.393
O24 Diabetes mellitus in pregnancy	0.606	0.394
B35-B49 Mycoses	0.606	0.394
M54 Dorsalgia	0.606	0.394
S92.2 Fracture of other tarsal bone(s)	0.606	0.394
J20-J22 Other acute lower respiratory infections	0.604	0.396
D69.9 Haemorrhagic condition, unspecified	0.601	0.398
S91.0 Open wound of ankle	0.601	0.398
S92.9 Fracture of foot, unspecified	0.601	0.399
S92.7 Multiple fractures of foot	0.601	0.399
S92.4 Fracture of great toe	0.601	0.399
S22.4 Multiple fractures of ribs	0.601	0.399
O92.1 Cracked nipple associated with childbirth	0.600	0.399
M51 Other intervertebral disk disorders	0.601	0.399
S92.1 Fracture of talus	0.600	0.400
D55-D59 Haemolytic anaemias	0.600	0.400
M06.4 Inflammatory polyarthropathy	0.600	0.400
Y42.5 Other oestrogens and progestogens	0.600	0.400
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.599	0.401
S37 Injury of urinary and pelvic organs	0.599	0.401
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.599	0.401
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.599	0.401
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.599	0.401
Y76.2 Prosthetic and other implants, materials and accessory devices	0.599	0.401
A09 Diarrhoea and gastro-enteritis of presumed infectious origin	0.598	0.402
M43.0 Spondylolysis	0.598	0.402
J15.0 Pneumonia due to Klebsiella pneumoniae	0.598	0.402
S29 Other and unspecified injuries of thorax	0.598	0.402
Y82 Other and unspecified medical devices associated with adverse incidents	0.598	0.402
Y81 General- and plastic-surgery devices associated with adverse incidents	0.598	0.402
Y80 Physical medicine devices associated with adverse incidents	0.598	0.402
Y78 Radiological devices associated with adverse incidents	0.598	0.402
Y77 Ophthalmic devices associated with adverse incidents	0.598	0.402
Y75 Neurological devices associated with adverse incidents	0.598	0.402
Y74 General hospital and personal-use devices associated with adverse incidents	0.598	0.402
Y73 Gastro-enterology and urology devices associated with adverse incidents	0.598	0.402
Y72 Otorhinolaryngological devices associated with adverse incidents	0.598	0.402
Y71 Cardiovascular devices associated with adverse incidents	0.598	0.402
Y70 Anaesthesiology devices associated with adverse incidents	0.598	0.402
M06.3 Rheumatoid nodule	0.598	0.402

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations