TreeWAS – Variant ID: rs79565709

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
Chapter IX Diseases of the circulatory system	1.000	0.000
# Top node	1.000	0.000
I30-I52 Other forms of heart disease	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.997	0.003
S00-S09 Injuries to the head	0.994	0.006
I05-I09 Chronic rheumatic heart diseases	0.992	0.008
Chapter IV Endocrine, nutritional and metabolic diseases	0.991	0.009
I45 Other conduction disorders	0.990	0.010
Chapter I Certain infectious and parasitic diseases	0.987	0.013
S02 Fracture of skull and facial bones	0.985	0.015
Chapter XI Diseases of the digestive system	0.981	0.019
Chapter XII Diseases of the skin and subcutaneous tissue	0.980	0.020
K70-K77 Diseases of liver	0.979	0.021
Chapter XXI Factors influencing health status and contact with health services	0.979	0.021
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.976	0.024
B95-B98 Bacterial, viral and other infectious agents	0.976	0.024
I60-I69 Cerebrovascular diseases	0.974	0.026
I46 Cardiac arrest	0.972	0.028
I70-I79 Diseases of arteries, arterioles and capillaries	0.971	0.029
L00-L08 Infections of the skin and subcutaneous tissue	0.969	0.031
L02 Cutaneous abscess, furuncle and carbuncle	0.967	0.033
K65-K67 Diseases of peritoneum	0.965	0.035
I50 Heart failure	0.965	0.035
I08 Multiple valve diseases	0.964	0.036
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.962	0.038
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.957	0.043
L02.4 Cutaneous abscess, furuncle and carbuncle of limb	0.956	0.044
K66 Other disorders of peritoneum	0.955	0.045
Z95 Presence of cardiac and vascular implants and grafts	0.953	0.047
Chapter XXII Codes for special purposes	0.952	0.048
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances	0.950	0.050
I45.1 Other and unspecified right bundle-branch block	0.947	0.053
K76 Other diseases of liver	0.944	0.056
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.944	0.056
K66.0 Peritoneal adhesions	0.943	0.057
S02.1 Fracture of base of skull	0.942	0.058
I46.0 Cardiac arrest with successful resuscitation	0.942	0.058
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.935	0.065
I67 Other cerebrovascular diseases	0.935	0.065
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.934	0.066
E70-E90 Metabolic disorders	0.933	0.067
Z89 Acquired absence of limb	0.928	0.072
E10-E14 Diabetes mellitus	0.928	0.072
I73 Other peripheral vascular diseases	0.923	0.077
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.922	0.078
Z95.0 Presence of cardiac pacemaker	0.918	0.082
M05-M14 Inflammatory polyarthropathies	0.914	0.086
Z88.5 Personal history of allergy to narcotic agent	0.912	0.088
I50.9 Heart failure, unspecified	0.911	0.089
S02.10 Fracture of base of skull (closed)	0.911	0.089
Chapter VII Diseases of the eye and adnexa	0.910	0.090
Z95.4 Presence of other heart-valve replacement	0.909	0.091
K76.0 Fatty (change of) liver, not elsewhere classified	0.908	0.092
K74 Fibrosis and cirrhosis of liver	0.908	0.092
I05 Rheumatic mitral valve diseases	0.907	0.093
E11 Non-insulin-dependent diabetes mellitus	0.903	0.097
I73.0 Raynaud's syndrome	0.899	0.101
Z90 Acquired absence of organs, not elsewhere classified	0.897	0.103
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.897	0.103
L80-L99 Other disorders of the skin and subcutaneous tissue	0.897	0.103
M13 Other arthritis	0.896	0.104
Z94 Transplanted organ and tissue status	0.896	0.104
E87 Other disorders of fluid, electrolyte and acid-base balance	0.894	0.106
S10-S19 Injuries to the neck	0.892	0.108
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.890	0.110
M13.9 Arthritis, unspecified	0.883	0.117
S02.8 Fractures of other skull and facial bones	0.883	0.117
I08.0 Disorders of both mitral and aortic valves	0.883	0.117
I49 Other cardiac arrhythmias	0.879	0.121
Z90.7 Acquired absence of genital organ(s)	0.878	0.122
Z29 Need for other prophylactic measures	0.875	0.125
S00 Superficial injury of head	0.873	0.127
I62 Other nontraumatic intracranial haemorrhage	0.871	0.129
L97 Ulcer of lower limb, not elsewhere classified	0.870	0.130
M80-M85 Disorders of bone density and structure	0.870	0.130
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.870	0.130
K76.6 Portal hypertension	0.869	0.131
K70 Alcoholic liver disease	0.866	0.134
Z89.5 Acquired absence of leg at or below knee	0.866	0.134
S06 Intracranial injury	0.861	0.139
Chapter XX External causes of morbidity and mortality	0.859	0.141
I70 Atherosclerosis	0.857	0.143
I67.8 Other specified cerebrovascular diseases	0.856	0.144
I08.1 Disorders of both mitral and tricuspid valves	0.855	0.145
I69 Sequelae of cerebrovascular disease	0.855	0.145
Z80 Family history of malignant neoplasm	0.854	0.146
Z92 Personal history of medical treatment	0.853	0.147
M13.99 Arthritis, unspecified (Site unspecified)	0.850	0.150
I45.4 Nonspecific intraventricular block	0.849	0.150
Z22 Carrier of infectious disease	0.845	0.155
Z92.6 Personal history of chemotherapy for neoplastic disease	0.844	0.156
K74.6 Other and unspecified cirrhosis of liver	0.843	0.157
E00-E07 Disorders of thyroid gland	0.842	0.158
A30-A49 Other bacterial diseases	0.841	0.159
H25-H28 Disorders of lens	0.840	0.160
I38 Endocarditis, valve unspecified	0.839	0.161
U88 Agent resistant to multiple antibiotics	0.838	0.162
I45.3 Trifascicular block	0.838	0.162
S02.4 Fracture of malar and maxillary bones	0.838	0.162
L89 Decubitus ulcer	0.836	0.164
T15-T19 Effects of foreign body entering through natural orifice	0.835	0.165
M13.90 Arthritis, unspecified (Multiple sites)	0.834	0.166
S40-S49 Injuries to the shoulder and upper arm	0.830	0.170
E87.6 Hypokalaemia	0.828	0.172
I05.9 Mitral valve disease, unspecified	0.826	0.174
H18 Other disorders of cornea	0.825	0.175
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.822	0.178
H26 Other cataract	0.822	0.178
E11.4 With neurological complications	0.822	0.178
Z89.4 Acquired absence of foot and ankle	0.820	0.180
I67.9 Cerebrovascular disease, unspecified	0.819	0.181
Z80.4 Family history of malignant neoplasm of genital organs	0.818	0.182
I36 Nonrheumatic tricuspid valve disorders	0.818	0.182
K73 Chronic hepatitis, not elsewhere classified	0.818	0.182
S20-S29 Injuries to the thorax	0.818	0.182
E87.5 Hyperkalaemia	0.817	0.183
Z94.8 Other transplanted organ and tissue status	0.814	0.186
I45.5 Other specified heart block	0.813	0.187
S09 Other and unspecified injuries of head	0.812	0.188
E88 Other metabolic disorders	0.812	0.188
S02.80 Fractures of other skull and facial bones (closed)	0.810	0.190
E11.5 With peripheral circulatory complications	0.807	0.193
M13.91 Arthritis, unspecified (Shoulder region)	0.805	0.195
M86-M90 Other osteopathies	0.805	0.195
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.805	0.195
I50.0 Congestive heart failure	0.805	0.195
B97 Viral agents as the cause of diseases classified to other chapters	0.804	0.196
L20-L30 Dermatitis and eczema	0.804	0.196
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.804	0.196
S00.9 Superficial injury of head, part unspecified	0.803	0.197
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified	0.802	0.198
I08.8 Other multiple valve diseases	0.801	0.199
K72 Hepatic failure, not elsewhere classified	0.801	0.199
E40-E46 Malnutrition	0.799	0.201
A49 Bacterial infection of unspecified site	0.799	0.201
S90-S99 Injuries to the ankle and foot	0.798	0.202
H26.9 Cataract, unspecified	0.798	0.202
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.798	0.202
K66.9 Disorder of peritoneum, unspecified	0.797	0.203
E05 Thyrotoxicosis [hyperthyroidism]	0.797	0.203
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.796	0.204
I47 Paroxysmal tachycardia	0.795	0.205
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.794	0.206
S02.3 Fracture of orbital floor	0.792	0.207
Z22.3 Carrier of other specified bacterial diseases	0.790	0.210
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters	0.790	0.210
I46.9 Cardiac arrest, unspecified	0.790	0.210
H18.5 Hereditary corneal dystrophies	0.790	0.210
Z95.8 Presence of other cardiac and vascular implants and grafts	0.790	0.210
I33 Acute and subacute endocarditis	0.789	0.211
B99-B99 Other infectious diseases	0.788	0.211
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.788	0.212
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters	0.787	0.213
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters	0.787	0.213
D50-D53 Nutritional anaemias	0.787	0.213
K70.9 Alcoholic liver disease, unspecified	0.786	0.214
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.784	0.216
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.784	0.216
R26.8 Other and unspecified abnormalities of gait and mobility	0.783	0.217
R26 Abnormalities of gait and mobility	0.783	0.217
Z92.3 Personal history of irradiation	0.783	0.217
M85 Other disorders of bone density and structure	0.782	0.218
I42 Cardiomyopathy	0.782	0.218
I49.1 Atrial premature depolarisation	0.781	0.219
L81 Other disorders of pigmentation	0.780	0.220
I35 Nonrheumatic aortic valve disorders	0.780	0.220
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.780	0.220
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.779	0.221
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.779	0.221
S02.0 Fracture of vault of skull	0.779	0.221
I71 Aortic aneurysm and dissection	0.779	0.221
M84 Disorders of continuity of bone	0.778	0.222
I07 Rheumatic tricuspid valve diseases	0.776	0.224
I45.6 Preexcitation syndrome	0.773	0.227
E11.3 With ophthalmic complications	0.769	0.231
Z94.0 Kidney transplant status	0.766	0.234
E11.2 With renal complications	0.766	0.234
I78 Diseases of capillaries	0.763	0.237
S70-S79 Injuries to the hip and thigh	0.763	0.237
E83 Disorders of mineral metabolism	0.762	0.238
Z29.2 Other prophylactic chemotherapy	0.761	0.239
Q50-Q56 Congenital malformations of genital organs	0.761	0.239
I09 Other rheumatic heart diseases	0.761	0.239
Z29.8 Other specified prophylactic measures	0.760	0.240
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.756	0.244
Z95.2 Presence of prosthetic heart valve	0.754	0.246
T00-T07 Injuries involving multiple body regions	0.753	0.247
H55-H59 Other disorders of eye and adnexa	0.752	0.248
Z88.3 Personal history of allergy to other anti-infective agents	0.752	0.248
Chapter XIV Diseases of the genitourinary system	0.751	0.249
N10-N16 Renal tubulo-interstitial diseases	0.750	0.250
Q20-Q28 Congenital malformations of the circulatory system	0.749	0.251
L89.1 Stage II decubitus ulcer	0.749	0.251
I50.1 Left ventricular failure	0.749	0.251
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.747	0.253
B65-B83 Helminthiases	0.745	0.254
I49.4 Other and unspecified premature depolarisation	0.745	0.255
Y60-Y69 Misadventures to patients during surgical and medical care	0.745	0.255
I45.8 Other specified conduction disorders	0.743	0.257
E05.9 Thyrotoxicosis, unspecified	0.743	0.257
N13 Obstructive and reflux uropathy	0.742	0.258
D50 Iron deficiency anaemia	0.739	0.261
Z83 Family history of other specific disorders	0.738	0.262
K75 Other inflammatory liver diseases	0.737	0.263
K35-K38 Diseases of appendix	0.735	0.265
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.734	0.266
Q80-Q89 Other congenital malformations	0.734	0.266
I63 Cerebral infarction	0.734	0.266
S80-S89 Injuries to the knee and lower leg	0.733	0.267
S00.3 Superficial injury of nose	0.733	0.267
S02.40 Fracture of malar and maxillary bones (closed)	0.732	0.268
I51 Complications and ill-defined descriptions of heart disease	0.732	0.268
M13.94 Arthritis, unspecified (Hand)	0.731	0.269
B20-B24 Human immunodeficiency virus [HIV] disease	0.731	0.269
S12 Fracture of neck	0.728	0.272
S60-S69 Injuries to the wrist and hand	0.728	0.272
M00-M03 Infectious arthropathies	0.727	0.273
A49.8 Other bacterial infections of unspecified site	0.727	0.273
D51 Vitamin B12 deficiency anaemia	0.725	0.275
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.725	0.275
I61 Intracerebral haemorrhage	0.725	0.275
B35-B49 Mycoses	0.725	0.275
Z88.7 Personal history of allergy to serum and vaccine	0.724	0.276
D50.8 Other iron deficiency anaemias	0.724	0.276
L02.1 Cutaneous abscess, furuncle and carbuncle of neck	0.724	0.276
Z90.4 Acquired absence of other parts of digestive tract	0.723	0.277
A80-A89 Viral infections of the central nervous system	0.722	0.278
S05 Injury of eye and orbit	0.722	0.278
K74.3 Primary biliary cirrhosis	0.721	0.279
K01 Embedded and impacted teeth	0.721	0.279
M45-M49 Spondylopathies	0.721	0.279
I70.0 Atherosclerosis of aorta	0.720	0.280
S00.7 Multiple superficial injuries of head	0.720	0.280
H10-H13 Disorders of conjunctiva	0.720	0.280
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.719	0.281
M84.1 Nonunion of fracture [pseudarthrosis]	0.718	0.282
I00-I02 Acute rheumatic fever	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
I52 Other heart disorders in diseases classified elsewhere	0.717	0.283
I48 Atrial fibrillation and flutter	0.717	0.283
I43 Cardiomyopathy in diseases classified elsewhere	0.717	0.283
I41 Myocarditis in diseases classified elsewhere	0.717	0.283
I40 Acute myocarditis	0.717	0.283
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.717	0.283
I32 Pericarditis in diseases classified elsewhere	0.717	0.283
E85 Amyloidosis	0.717	0.283
H20 Iridocyclitis	0.716	0.284
T17 Foreign body in respiratory tract	0.716	0.284
S02.2 Fracture of nasal bones	0.716	0.284
T33-T35 Frostbite	0.715	0.285
T26-T28 Burns and corrosions confined to eye and internal organs	0.715	0.285
T20-T25 Burns and corrosions of external body surface, specified by site	0.715	0.285
I49.8 Other specified cardiac arrhythmias	0.713	0.287
S08 Traumatic amputation of part of head	0.713	0.287
S07 Crushing injury of head	0.713	0.287
S04 Injury of cranial nerves	0.713	0.287
S03 Dislocation, sprain and strain of joints and ligaments of head	0.713	0.287
E20-E35 Disorders of other endocrine glands	0.712	0.288
N17-N19 Renal failure	0.712	0.288
I06 Rheumatic aortic valve diseases	0.711	0.288
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters	0.710	0.290
I45.0 Right fascicular block	0.710	0.290
L89.9 Decubitus ulcer and pressure area, unspecified	0.710	0.290
B85-B89 Pediculosis, acariasis and other infestations	0.707	0.292
B50-B64 Protozoal diseases	0.707	0.292
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.707	0.292
A75-A79 Rickettsioses	0.707	0.292
A70-A74 Other diseases caused by chlamydiae	0.707	0.292
A65-A69 Other spirochaetal diseases	0.707	0.292
A20-A28 Certain zoonotic bacterial diseases	0.707	0.292
A15-A19 Tuberculosis	0.707	0.292
S02.9 Fracture of skull and facial bones, part unspecified	0.706	0.294
S02.7 Multiple fractures involving skull and facial bones	0.706	0.294
I34 Nonrheumatic mitral valve disorders	0.706	0.294
I35.2 Aortic (valve) stenosis with insufficiency	0.705	0.295
E11.6 With other specified complications	0.704	0.295
M85.8 Other specified disorders of bone density and structure	0.704	0.296
I42.9 Cardiomyopathy, unspecified	0.703	0.297
L10-L14 Bullous disorders	0.703	0.297
K77 Liver disorders in diseases classified elsewhere	0.702	0.298
K71 Toxic liver disease	0.702	0.298
I49.0 Ventricular fibrillation and flutter	0.702	0.298
S06.2 Diffuse brain injury	0.701	0.299
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.701	0.299
M60-M63 Disorders of muscles	0.700	0.300
Z29.0 Isolation	0.700	0.300
N13.8 Other obstructive and reflux uropathy	0.699	0.301
I68 Cerebrovascular disorders in diseases classified elsewhere	0.698	0.301
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.698	0.301
S06.3 Focal brain injury	0.698	0.302
B15-B19 Viral hepatitis	0.698	0.302
I67.1 Cerebral aneurysm, nonruptured	0.697	0.303
I46.1 Sudden cardiac death, so described	0.697	0.303
S02.5 Fracture of tooth	0.697	0.303
B90-B94 Sequelae of infectious and parasitic diseases	0.696	0.304
H46-H48 Disorders of optic nerve and visual pathways	0.696	0.304
I37 Pulmonary valve disorders	0.696	0.304
A50-A64 Infections with a predominantly sexual mode of transmission	0.696	0.304
E50-E64 Other nutritional deficiencies	0.696	0.304
K76.7 Hepatorenal syndrome	0.695	0.305
K70.0 Alcoholic fatty liver	0.695	0.305
E87.0 Hyperosmolality and hypernatraemia	0.695	0.305
M13.92 Arthritis, unspecified (Upper arm)	0.695	0.305
L04 Acute lymphadenitis	0.694	0.305
L01 Impetigo	0.694	0.305
L00 Staphylococcal scalded skin syndrome	0.694	0.305
Z98 Other postsurgical states	0.693	0.307
I67.2 Cerebral atherosclerosis	0.693	0.307
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites	0.693	0.307
L02.0 Cutaneous abscess, furuncle and carbuncle of face	0.693	0.307
K67 Disorders of peritoneum in infectious diseases classified elsewhere	0.692	0.308
K73.9 Chronic hepatitis, unspecified	0.692	0.308
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters	0.692	0.308
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.692	0.308
I08.9 Multiple valve disease, unspecified	0.691	0.309
I08.2 Disorders of both aortic and tricuspid valves	0.691	0.309
E80 Disorders of porphyrin and bilirubin metabolism	0.690	0.310
X20-X29 Contact with venomous animals and plants	0.689	0.311
K70.1 Alcoholic hepatitis	0.688	0.312
H53-H54 Visual disturbances and blindness	0.688	0.312
U80 Agent resistant to penicillin and related antibiotics	0.688	0.312
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.688	0.312
V10-V19 Pedal cyclist injured in transport accident	0.687	0.313
E65-E68 Obesity and other hyperalimentation	0.686	0.314
S09.9 Unspecified injury of head	0.686	0.314
S10 Superficial injury of neck	0.685	0.314
K66.1 Haemoperitoneum	0.685	0.315
K66.8 Other specified disorders of peritoneum	0.684	0.316
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters	0.683	0.317
M14 Arthropathies in other diseases classified elsewhere	0.682	0.318
I05.0 Mitral stenosis	0.682	0.318
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.682	0.318
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.682	0.318
S40 Superficial injury of shoulder and upper arm	0.681	0.319
K65 Peritonitis	0.681	0.319
H26.4 After-cataract	0.681	0.319
L81.4 Other melanin hyperpigmentation	0.680	0.320
M10 Gout	0.680	0.320
T09 Other injuries of spine and trunk, level unspecified	0.680	0.320
S20 Superficial injury of thorax	0.679	0.321
Z88.2 Personal history of allergy to sulphonamides	0.679	0.321
I74 Arterial embolism and thrombosis	0.679	0.321
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.679	0.321
K06 Other disorders of gingiva and edentulous alveolar ridge	0.679	0.321
N18 Chronic renal failure	0.679	0.321
L95 Vasculitis limited to skin, not elsewhere classified	0.679	0.321
M06 Other rheumatoid arthritis	0.678	0.322
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.678	0.322
S14 Injury of nerves and spinal cord at neck level	0.678	0.322
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.678	0.322
I70.1 Atherosclerosis of renal artery	0.678	0.322
I05.2 Mitral stenosis with insufficiency	0.678	0.322
Z84 Family history of other conditions	0.677	0.323
K76.5 Hepatic veno-occlusive disease	0.677	0.323
K76.4 Peliosis hepatis	0.677	0.323
K76.3 Infarction of liver	0.677	0.323
K76.2 Central haemorrhagic necrosis of liver	0.677	0.323
K76.1 Chronic passive congestion of liver	0.677	0.323
Z28 Immunisation not carried out	0.677	0.323
Z27 Need for immunisation against combinations of infectious diseases	0.677	0.323
Z26 Need for immunisation against other single infectious diseases	0.677	0.323
Z25 Need for immunisation against other single viral diseases	0.677	0.323
Z24 Need for immunisation against certain single viral diseases	0.677	0.323
Z23 Need for immunisation against single bacterial diseases	0.677	0.323
Z20 Contact with and exposure to communicable diseases	0.677	0.323
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status	0.677	0.323
S02.11 Fracture of base of skull (open)	0.675	0.325
S19 Other and unspecified injuries of neck	0.675	0.325
V01-V09 Pedestrian injured in transport accident	0.675	0.325
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.675	0.325
I45.9 Conduction disorder, unspecified	0.673	0.327
L80 Vitiligo	0.673	0.327
K72.9 Hepatic failure, unspecified	0.673	0.327
A00-A09 Intestinal infectious diseases	0.672	0.328
E83.3 Disorders of phosphorus metabolism	0.671	0.329
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.671	0.329
U89 Agent resistant to other and unspecified antibiotics	0.671	0.329
E13 Other specified diabetes mellitus	0.671	0.329
I67.7 Cerebral arteritis, not elsewhere classified	0.670	0.330
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.670	0.330
I67.5 Moyamoya disease	0.670	0.330
I67.4 Hypertensive encephalopathy	0.670	0.330
I67.3 Progressive vascular leukoencephalopathy	0.670	0.330
I67.0 Dissection of cerebral arteries, nonruptured	0.670	0.330
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.670	0.330
E07 Other disorders of thyroid	0.669	0.331
E84 Cystic fibrosis	0.669	0.331
E79 Disorders of purine and pyrimidine metabolism	0.669	0.331
E77 Disorders of glycoprotein metabolism	0.669	0.331
E76 Disorders of glycosaminoglycan metabolism	0.669	0.331
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.669	0.331
E74 Other disorders of carbohydrate metabolism	0.669	0.331
E72 Other disorders of amino-acid metabolism	0.669	0.331
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.669	0.331
E70 Disorders of aromatic amino-acid metabolism	0.669	0.331
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.669	0.331
M86 Osteomyelitis	0.668	0.332
E10 Insulin-dependent diabetes mellitus	0.667	0.333
S06.5 Traumatic subdural haemorrhage	0.666	0.334
S49 Other and unspecified injuries of shoulder and upper arm	0.666	0.334
Z89.9 Acquired absence of limb, unspecified	0.666	0.334
Z89.8 Acquired absence of upper and lower limbs [any level]	0.666	0.334
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]	0.666	0.334
Z89.3 Acquired absence of both upper limbs [any level]	0.666	0.334
Z89.2 Acquired absence of upper limb above wrist	0.666	0.334
Z89.1 Acquired absence of hand and wrist	0.666	0.334
Z89.0 Acquired absence of finger(s) [including thumb], unilateral	0.666	0.334
E12 Malnutrition-related diabetes mellitus	0.665	0.334
M11 Other crystal arthropathies	0.665	0.334
Q00-Q07 Congenital malformations of the nervous system	0.665	0.334
W50-W64 Exposure to animate mechanical forces	0.665	0.335
L89.2 Stage III decubitus ulcer	0.664	0.335
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.664	0.336
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.664	0.336
I05.1 Rheumatic mitral insufficiency	0.662	0.338
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.662	0.338
N18.3 Chronic kidney disease, stage 3	0.662	0.338
E46 Unspecified protein-energy malnutrition	0.662	0.338
Q65 Congenital deformities of hip	0.662	0.338
I73.8 Other specified peripheral vascular diseases	0.661	0.338
I73.1 Thromboangiitis obliterans [Buerger]	0.661	0.338
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.661	0.339
Q35-Q37 Cleft lip and cleft palate	0.661	0.339
Q30-Q34 Congenital malformations of the respiratory system	0.661	0.339
W20-W49 Exposure to inanimate mechanical forces	0.661	0.339
I70.2 Atherosclerosis of arteries of the extremities	0.659	0.341
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.659	0.341
L30 Other dermatitis	0.659	0.341
X50-X57 Overexertion, travel and privation	0.658	0.341
M13.98 Arthritis, unspecified (Other)	0.658	0.342
I45.2 Bifascicular block	0.658	0.342
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.657	0.343
I30 Acute pericarditis	0.657	0.343
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters	0.656	0.344
M12 Other specific arthropathies	0.655	0.344
M09 Juvenile arthritis in diseases classified elsewhere	0.655	0.344
M08 Juvenile arthritis	0.655	0.344
I60 Subarachnoid haemorrhage	0.654	0.345
R41 Other symptoms and signs involving cognitive functions and awareness	0.655	0.345
S02.30 Fracture of orbital floor (closed)	0.654	0.346
H40-H42 Glaucoma	0.654	0.346
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.654	0.346
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.654	0.346
Z99.1 Dependence on respirator	0.654	0.346
Z90.8 Acquired absence of other organs	0.653	0.346
N13.4 Hydroureter	0.653	0.347
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.653	0.347
S66 Injury of muscle and tendon at wrist and hand level	0.653	0.347
H18.1 Bullous keratopathy	0.652	0.347
R42 Dizziness and giddiness	0.653	0.347
N13.5 Kinking and stricture of ureter without hydronephrosis	0.652	0.348
S81 Open wound of lower leg	0.651	0.349
A49.0 Staphylococcal infection, unspecified	0.651	0.349
Z81 Family history of mental and behavioural disorders	0.651	0.349
Y95 Nosocomial condition	0.651	0.349
K74.5 Biliary cirrhosis, unspecified	0.651	0.349
K74.4 Secondary biliary cirrhosis	0.651	0.349
K74.2 Hepatic fibrosis with hepatic sclerosis	0.651	0.349
K74.1 Hepatic sclerosis	0.651	0.349
N00-N08 Glomerular diseases	0.651	0.349
I05.8 Other mitral valve diseases	0.650	0.349
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.650	0.350
Z80.8 Family history of malignant neoplasm of other organs or systems	0.650	0.350
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.649	0.351
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.648	0.352
Z80.3 Family history of malignant neoplasm of breast	0.648	0.352
E11.8 With unspecified complications	0.648	0.352
E11.7 With multiple complications	0.648	0.352
E11.1 With ketoacidosis	0.648	0.352
E11.0 With coma	0.648	0.352
Z83.7 Family history of diseases of the digestive system	0.648	0.352
I10-I15 Hypertensive diseases	0.648	0.352
Q21 Congenital malformations of cardiac septa	0.647	0.353
A49.9 Bacterial infection, unspecified	0.647	0.353
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock	0.647	0.353
Chapter VIII Diseases of the ear and mastoid process	0.646	0.354
B99 Other and unspecified infectious diseases	0.646	0.354
M07 Psoriatic and enteropathic arthropathies	0.646	0.354
D52 Folate deficiency anaemia	0.645	0.355
Q38-Q45 Other congenital malformations of the digestive system	0.644	0.355
B97.8 Other viral agents as the cause of diseases classified to other chapters	0.644	0.356
K01.1 Impacted teeth	0.644	0.356
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.644	0.356
K04 Diseases of pulp and periapical tissues	0.644	0.356
K76.9 Liver disease, unspecified	0.643	0.357
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.643	0.357
L94 Other localised connective tissue disorders	0.643	0.357
L87 Transepidermal elimination disorders	0.643	0.357
L88 Pyoderma gangrenosum	0.643	0.357
L86 Keratoderma in diseases classified elsewhere	0.643	0.357
S41 Open wound of shoulder and upper arm	0.642	0.357
M13.8 Other specified arthritis	0.642	0.357
M13.1 Monoarthritis, not elsewhere classified	0.642	0.357
Z94.9 Transplanted organ and tissue status, unspecified	0.642	0.358
Z94.6 Bone transplant status	0.642	0.358
Z94.5 Skin transplant status	0.642	0.358
Z94.3 Heart and lungs transplant status	0.642	0.358
Z94.2 Lung transplant status	0.642	0.358
Z94.1 Heart transplant status	0.642	0.358
E87.4 Mixed disorder of acid-base balance	0.641	0.359

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations