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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2215614
log Bayes Factor = 7.56312
Chromosome 7   position 35,277,093  (GRCh37) Explore rs2215614 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
I20 Angina pectoris
0.000 0.000 1.000
I25.2 Old myocardial infarction
0.000 0.002 0.998
I25.1 Atherosclerotic heart disease
0.000 0.003 0.997
I20.8 Other forms of angina pectoris
0.000 0.004 0.996
I20.0 Unstable angina
0.000 0.010 0.990
I30-I52 Other forms of heart disease
0.000 0.012 0.988
Chapter IX Diseases of the circulatory system
0.000 0.014 0.986
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.016 0.984
I35 Nonrheumatic aortic valve disorders
0.000 0.017 0.983
I21 Acute myocardial infarction
0.000 0.018 0.982
I21.9 Acute myocardial infarction, unspecified
0.000 0.019 0.981
I51.8 Other ill-defined heart diseases
0.000 0.023 0.977
I05-I09 Chronic rheumatic heart diseases
0.000 0.023 0.977
I51 Complications and ill-defined descriptions of heart disease
0.000 0.025 0.975
I25.5 Ischaemic cardiomyopathy
0.000 0.027 0.973
I05 Rheumatic mitral valve diseases
0.000 0.032 0.968
I35.1 Aortic (valve) insufficiency
0.000 0.039 0.961
I47 Paroxysmal tachycardia
0.000 0.050 0.950
I35.0 Aortic (valve) stenosis
0.000 0.051 0.949
I05.9 Mitral valve disease, unspecified
0.000 0.051 0.949
I47.2 Ventricular tachycardia
0.000 0.073 0.927
I45 Other conduction disorders
0.000 0.074 0.926
I35.8 Other aortic valve disorders
0.000 0.119 0.881
I44 Atrioventricular and left bundle-branch block
0.000 0.120 0.880
I45.1 Other and unspecified right bundle-branch block
0.000 0.155 0.845
I44.7 Left bundle-branch block, unspecified
0.000 0.159 0.841
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.172 0.828
I05.2 Mitral stenosis with insufficiency
0.000 0.180 0.820
I45.2 Bifascicular block
0.000 0.185 0.815
I00-I02 Acute rheumatic fever
0.000 0.196 0.804
I45.8 Other specified conduction disorders
0.000 0.199 0.801
I22 Subsequent myocardial infarction
0.000 0.207 0.793
I36 Nonrheumatic tricuspid valve disorders
0.000 0.208 0.792
I06 Rheumatic aortic valve diseases
0.000 0.211 0.789
I09 Other rheumatic heart diseases
0.000 0.216 0.784
I05.0 Mitral stenosis
0.000 0.216 0.784
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.220 0.780
I44.6 Other and unspecified fascicular block
0.000 0.227 0.773
I45.5 Other specified heart block
0.000 0.233 0.766
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.244 0.756
I45.3 Trifascicular block
0.000 0.250 0.750
I44.3 Other and unspecified atrioventricular block
0.000 0.259 0.741
I42 Cardiomyopathy
0.000 0.266 0.734
I05.1 Rheumatic mitral insufficiency
0.000 0.271 0.729
I23 Certain current complications following acute myocardial infarction
0.000 0.278 0.722
I37 Pulmonary valve disorders
0.000 0.280 0.720
I52 Other heart disorders in diseases classified elsewhere
0.000 0.291 0.708
I48 Atrial fibrillation and flutter
0.000 0.291 0.708
I41 Myocarditis in diseases classified elsewhere
0.000 0.291 0.708
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.291 0.708
I32 Pericarditis in diseases classified elsewhere
0.000 0.291 0.708
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.296 0.704
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.297 0.703
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.297 0.703
I47.0 Reentry ventricular arrhythmia
0.000 0.299 0.701
I25.6 Silent myocardial ischaemia
0.000 0.300 0.700
I51.5 Myocardial degeneration
0.000 0.301 0.699
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.301 0.699
I47.1 Supraventricular tachycardia
0.000 0.302 0.698
I05.8 Other mitral valve diseases
0.000 0.306 0.694
I00 Rheumatic fever without mention of heart involvement
0.000 0.327 0.673
I42.6 Alcoholic cardiomyopathy
0.000 0.346 0.654
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.346 0.653
I20.9 Angina pectoris, unspecified
0.000 0.349 0.651
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.349 0.651
I20.1 Angina pectoris with documented spasm
0.000 0.349 0.651
I40 Acute myocarditis
0.000 0.350 0.649
I09.9 Rheumatic heart disease, unspecified
0.000 0.354 0.646
I07 Rheumatic tricuspid valve diseases
0.000 0.356 0.644
I06.0 Rheumatic aortic stenosis
0.000 0.358 0.642
I49 Other cardiac arrhythmias
0.000 0.362 0.638
I22.8 Subsequent myocardial infarction of other sites
0.000 0.364 0.636
I44.5 Left posterior fascicular block
0.000 0.369 0.631
I45.0 Right fascicular block
0.000 0.373 0.626
I10-I15 Hypertensive diseases
0.000 0.376 0.624
I45.4 Nonspecific intraventricular block
0.000 0.382 0.618
I44.4 Left anterior fascicular block
0.000 0.389 0.611
I21.4 Acute subendocardial myocardial infarction
0.000 0.396 0.604
I08 Multiple valve diseases
0.000 0.398 0.602
I33 Acute and subacute endocarditis
0.000 0.399 0.600
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.401 0.599
I49.1 Atrial premature depolarisation
0.000 0.412 0.588
I44.0 Atrioventricular block, first degree
0.000 0.413 0.587
I06.1 Rheumatic aortic insufficiency
0.000 0.416 0.584
I23.8 Other current complications following acute myocardial infarction
0.000 0.422 0.578
I02 Rheumatic chorea
0.000 0.423 0.576
I01 Rheumatic fever with heart involvement
0.000 0.423 0.576
I50 Heart failure
0.000 0.429 0.571
I34 Nonrheumatic mitral valve disorders
0.000 0.431 0.569
I42.9 Cardiomyopathy, unspecified
0.000 0.432 0.568
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.432 0.568
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.432 0.568
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.432 0.568
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.432 0.568
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.434 0.565
I06.8 Other rheumatic aortic valve diseases
0.000 0.434 0.565
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.434 0.565
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.436 0.564
I51.7 Cardiomegaly
0.000 0.436 0.564
I09.8 Other specified rheumatic heart diseases
0.000 0.438 0.562
I09.2 Chronic rheumatic pericarditis
0.000 0.438 0.562
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.438 0.562
I09.0 Rheumatic myocarditis
0.000 0.438 0.562
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.439 0.561
I51.9 Heart disease, unspecified
0.000 0.442 0.558
I25.4 Coronary artery aneurysm
0.000 0.444 0.556
I30 Acute pericarditis
0.000 0.451 0.549
I42.8 Other cardiomyopathies
0.000 0.455 0.545
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.459 0.541
I42.4 Endocardial fibroelastosis
0.000 0.460 0.540
I10 Essential (primary) hypertension
0.000 0.462 0.538
I37.0 Pulmonary valve stenosis
0.000 0.465 0.535
I49.3 Ventricular premature depolarisation
0.000 0.465 0.535
I49.0 Ventricular fibrillation and flutter
0.000 0.466 0.534
I42.5 Other restrictive cardiomyopathy
0.000 0.473 0.526
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.473 0.526
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.482 0.518
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.482 0.518
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.482 0.518
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.482 0.518
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.482 0.518
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.482 0.518
I37.9 Pulmonary valve disorder, unspecified
0.000 0.484 0.516
I37.8 Other pulmonary valve disorders
0.000 0.484 0.516
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.484 0.516
I46 Cardiac arrest
0.000 0.485 0.515
I50.0 Congestive heart failure
0.000 0.486 0.514
I37.1 Pulmonary valve insufficiency
0.000 0.491 0.509
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.492 0.508
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.492 0.508
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.492 0.508
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.492 0.508
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.492 0.508
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.492 0.508
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.492 0.508
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.492 0.508
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.492 0.508
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.492 0.508
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.492 0.508
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.492 0.508
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.492 0.508
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.492 0.508
I48.4 Atypical atrial flutter
0.000 0.492 0.508
I48.3 Typical atrial flutter
0.000 0.492 0.508
I48.2 Chronic atrial fibrillation
0.000 0.492 0.508
I48.1 Persistent atrial fibrillation
0.000 0.492 0.508
I48.0 Paroxysmal atrial fibrillation
0.000 0.492 0.508
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.492 0.508
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.492 0.508
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.492 0.508
I24 Other acute ischaemic heart diseases
0.000 0.496 0.504
I51.0 Cardiac septal defect, acquired
0.000 0.498 0.502
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.506 0.494
I42.2 Other hypertrophic cardiomyopathy
0.000 0.508 0.492
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.516 0.484
I34.2 Nonrheumatic mitral (valve) stenosis
0.000 0.524 0.476
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.526 0.474
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.531 0.469
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.531 0.469
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.534 0.466
I40.8 Other acute myocarditis
0.000 0.534 0.466
I40.1 Isolated myocarditis
0.000 0.534 0.466
I07.9 Tricuspid valve disease, unspecified
0.000 0.538 0.462
I07.8 Other tricuspid valve diseases
0.000 0.538 0.462
I07.2 Tricuspid stenosis with insufficiency
0.000 0.538 0.462
I07.0 Tricuspid stenosis
0.000 0.538 0.462
I49.2 Junctional premature depolarisation
0.000 0.542 0.458
I40.0 Infective myocarditis
0.000 0.548 0.451
I25.3 Aneurysm of heart
0.000 0.549 0.451
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.552 0.448
I08.0 Disorders of both mitral and aortic valves
0.000 0.552 0.448
I13 Hypertensive heart and renal disease
0.000 0.553 0.447
I51.6 Cardiovascular disease, unspecified
0.000 0.559 0.440
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.561 0.439
I24.8 Other forms of acute ischaemic heart disease
0.000 0.573 0.427
I40.9 Acute myocarditis, unspecified
0.000 0.576 0.424
I33.9 Acute endocarditis, unspecified
0.000 0.578 0.422
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.583 0.417
I08.9 Multiple valve disease, unspecified
0.000 0.586 0.414
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.586 0.413
I01.8 Other acute rheumatic heart disease
0.000 0.586 0.413
I01.2 Acute rheumatic myocarditis
0.000 0.586 0.413
I01.1 Acute rheumatic endocarditis
0.000 0.586 0.413
I01.0 Acute rheumatic pericarditis
0.000 0.586 0.413
I02.9 Rheumatic chorea without heart involvement
0.000 0.586 0.413
I02.0 Rheumatic chorea with heart involvement
0.000 0.586 0.413
I07.1 Tricuspid insufficiency
0.000 0.595 0.405
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.597 0.403
I45.6 Preexcitation syndrome
0.000 0.597 0.402
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.601 0.399
I12 Hypertensive renal disease
0.000 0.606 0.394
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.606 0.394
I30.1 Infective pericarditis
0.000 0.607 0.392
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.611 0.389
I46.9 Cardiac arrest, unspecified
0.000 0.611 0.389
I49.8 Other specified cardiac arrhythmias
0.000 0.619 0.381
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.622 0.378
I46.1 Sudden cardiac death, so described
0.000 0.630 0.370
I11 Hypertensive heart disease
0.000 0.634 0.366
I44.1 Atrioventricular block, second degree
0.000 0.636 0.364
I08.8 Other multiple valve diseases
0.000 0.644 0.355
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.646 0.354
I24.1 Dressler's syndrome
0.000 0.647 0.353
I30.8 Other forms of acute pericarditis
0.000 0.653 0.347
I35.9 Aortic valve disorder, unspecified
0.000 0.654 0.345
I15 Secondary hypertension
0.000 0.660 0.340
I33.0 Acute and subacute infective endocarditis
0.000 0.664 0.336
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.679 0.321
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.679 0.321
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.679 0.321
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.679 0.321
I30.9 Acute pericarditis, unspecified
0.000 0.691 0.309
I34.0 Mitral (valve) insufficiency
0.000 0.695 0.305
I49.9 Cardiac arrhythmia, unspecified
0.000 0.697 0.303
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.713 0.287
I22.0 Subsequent myocardial infarction of anterior wall
0.001 0.718 0.281
I50.1 Left ventricular failure
0.000 0.721 0.279
I12.0 Hypertensive renal disease with renal failure
0.000 0.728 0.272
I45.9 Conduction disorder, unspecified
0.001 0.731 0.268
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.732 0.268
I31 Other diseases of pericardium
0.000 0.738 0.262
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.747 0.253
I49.5 Sick sinus syndrome
0.000 0.749 0.251
I15.8 Other secondary hypertension
0.000 0.756 0.244
I12.9 Hypertensive renal disease without renal failure
0.000 0.756 0.244
I15.9 Seconday hypertension, unspecified
0.000 0.758 0.242
I15.1 Hypertension secondary to other renal disorders
0.000 0.761 0.239
I51.4 Myocarditis, unspecified
0.003 0.766 0.230
I15.0 Renovascular hypertension
0.000 0.773 0.226
I34.1 Mitral (valve) prolapse
0.000 0.792 0.208
I42.0 Dilated cardiomyopathy
0.000 0.794 0.206
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.802 0.197
I31.8 Other specified diseases of pericardium
0.000 0.812 0.188
I31.2 Haemopericardium, not elsewhere classified
0.000 0.812 0.188
I15.2 Hypertension secondary to endocrine disorders
0.001 0.819 0.180
I28 Other diseases of pulmonary vessels
0.000 0.823 0.176
I38 Endocarditis, valve unspecified
0.000 0.825 0.175
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.829 0.171
I31.1 Chronic constrictive pericarditis
0.000 0.832 0.168
I49.4 Other and unspecified premature depolarisation
0.000 0.836 0.164
I31.0 Chronic adhesive pericarditis
0.000 0.837 0.162
I31.9 Disease of pericardium, unspecified
0.000 0.853 0.147
J98.4 Other disorders of lung
0.000 0.855 0.145
J98 Other respiratory disorders
0.000 0.860 0.140
J98.0 Diseases of bronchus, not elsewhere classified
0.000 0.863 0.137
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.873 0.127
I28.1 Aneurysm of pulmonary artery
0.000 0.873 0.127
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.873 0.127
J98.2 Interstitial emphysema
0.000 0.874 0.126
I46.0 Cardiac arrest with successful resuscitation
0.000 0.875 0.125
J98.9 Respiratory disorder, unspecified
0.000 0.879 0.121
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.888 0.112
I28.8 Other specified diseases of pulmonary vessels
0.000 0.889 0.111
I26 Pulmonary embolism
0.000 0.889 0.111
J95-J99 Other diseases of the respiratory system
0.000 0.893 0.107
I50.9 Heart failure, unspecified
0.000 0.897 0.103
J98.5 Diseases of mediastinum, not elsewhere classified
0.000 0.899 0.101
J99 Respiratory disorders in diseases classified elsewhere
0.000 0.899 0.101
J98.3 Compensatory emphysema
0.000 0.899 0.101
I99 Other and unspecified disorders of circulatory system
0.000 0.902 0.098
J98.8 Other specified respiratory disorders
0.000 0.902 0.097
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.906 0.094
J99.8 Respiratory disorders in other diseases classified elsewhere
0.000 0.906 0.094
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.907 0.093
I97.1 Other functional disturbances following cardiac surgery
0.000 0.909 0.091
I44.2 Atrioventricular block, complete
0.000 0.911 0.089
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.914 0.086
I74 Arterial embolism and thrombosis
0.000 0.917 0.083
J99.0 Rheumatoid lung disease
0.000 0.919 0.081
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.920 0.080
I97.0 Postcardiotomy syndrome
0.000 0.920 0.080
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.922 0.078
J96 Respiratory failure, not elsewhere classified
0.000 0.923 0.077
I72 Other aneurysm
0.000 0.924 0.076
J99.1 Respiratory disorders in other diffuse connective tissue disorders
0.000 0.925 0.075
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.928 0.072
J98.6 Disorders of diaphragm
0.000 0.928 0.072
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.930 0.070
J95.9 Postprocedural respiratory disorder, unspecified
0.000 0.930 0.070
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.931 0.069
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.931 0.069
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.931 0.069
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.933 0.067
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.933 0.067
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.933 0.067
I72.2 Aneurysm of renal artery
0.000 0.934 0.065
I31.3 Pericardial effusion (noninflammatory)
0.000 0.935 0.065
I72.8 Aneurysm of other specified arteries
0.000 0.938 0.062
I27 Other pulmonary heart diseases
0.000 0.939 0.061
I72.0 Aneurysm of carotid artery
0.000 0.942 0.058
I71 Aortic aneurysm and dissection
0.000 0.942 0.058
I72.1 Aneurysm of artery of upper extremity
0.000 0.943 0.057
I98 Other disorders of circulatory system in diseases classified elsewhere
0.001 0.944 0.056
J95.4 Mendelson's syndrome
0.000 0.944 0.056
J95.3 Chronic pulmonary insufficiency following surgery
0.000 0.944 0.056
J95.2 Acute pulmonary insufficiency following nonthoracic surgery
0.000 0.944 0.056
J95.1 Acute pulmonary insufficiency following thoracic surgery
0.000 0.944 0.056
J96.9 Respiratory failure, unspecified
0.000 0.944 0.055
J96.1 Chronic respiratory failure
0.000 0.944 0.055
J96.0 Acute respiratory failure
0.000 0.944 0.055
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.945 0.055
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.945 0.055
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.945 0.055
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.945 0.055
I72.9 Aneurysm of unspecified site
0.000 0.945 0.054
I72.4 Aneurysm of artery of lower extremity
0.000 0.946 0.054
J95.5 Postprocedural subglottic stenosis
0.000 0.946 0.053
I74.8 Embolism and thrombosis of other arteries
0.000 0.947 0.053
J95.0 Tracheostomy malfunction
0.000 0.949 0.051
I70 Atherosclerosis
0.000 0.953 0.047
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.954 0.046
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.955 0.045
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.955 0.045
I27.1 Kyphoscoliotic heart disease
0.000 0.956 0.044
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.957 0.042
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.958 0.042
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.958 0.042
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.958 0.042
I71.0 Dissection of aorta [any part]
0.000 0.958 0.042
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.959 0.041
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.001 0.959 0.040
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.001 0.959 0.040
I98.0 Cardiovascular syphilis
0.001 0.959 0.040
J96.09 Acute respiratory failure; Type unspecified
0.000 0.960 0.040
J96.01 Acute respiratory failure; Type II [hypercapnic]
0.000 0.960 0.040
J96.00 Acute respiratory failure; Type I [hypoxic]
0.000 0.960 0.040
J96.19 Chronic respiratory failure; Type unspecified
0.000 0.960 0.040
J96.11 Chronic respiratory failure; Type II [hypercapnic]
0.000 0.960 0.040
J96.10 Chronic respiratory failure; Type I [hypoxic]
0.000 0.960 0.040
J96.99 Respiratory failure, unspecified; Type unspecified
0.000 0.960 0.040
J96.91 Respiratory failure unspecified; Type II [hypercapnic]
0.000 0.960 0.040
J96.90 Respiratory failure, unspecified; Type I [hypoxic]
0.000 0.960 0.040
I79.1 Aortitis in diseases classified elsewhere
0.000 0.960 0.040
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.960 0.040
J95.8 Other postprocedural respiratory disorders
0.000 0.961 0.039
I27.9 Pulmonary heart disease, unspecified
0.000 0.961 0.039
I27.8 Other specified pulmonary heart diseases
0.000 0.961 0.038
I95 Hypotension
0.000 0.962 0.038
I70.8 Atherosclerosis of other arteries
0.000 0.966 0.034
I70.9 Generalised and unspecified atherosclerosis
0.000 0.966 0.034
G47.3 Sleep apnoea
0.033 0.967 0.000
I27.0 Primary pulmonary hypertension
0.000 0.967 0.033
I72.3 Aneurysm of iliac artery
0.000 0.968 0.032
I70.1 Atherosclerosis of renal artery
0.000 0.969 0.031
I95.8 Other hypotension
0.000 0.970 0.030
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.971 0.029
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.972 0.028
I70.0 Atherosclerosis of aorta
0.000 0.973 0.027
I95.2 Hypotension due to drugs
0.000 0.973 0.027
I95.0 Idiopathic hypotension
0.000 0.973 0.026
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.001 0.975 0.024
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.975 0.024
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.975 0.024
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.975 0.024
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.975 0.024
I74.5 Embolism and thrombosis of iliac artery
0.000 0.976 0.023
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.977 0.022
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.978 0.022
I78 Diseases of capillaries
0.000 0.979 0.021
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.980 0.019
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.980 0.019
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.981 0.019
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.981 0.018
I98.2 Oesophageal varices in diseases classified elsewhere
0.001 0.985 0.014
Z95.5 Presence of coronary angioplasty implant and graft
0.000 0.985 0.015
I86.4 Gastric varices
0.014 0.986 0.000
I78.9 Disease of capillaries, unspecified
0.000 0.987 0.013
I78.8 Other diseases of capillaries
0.000 0.987 0.013
Y84.0 Cardiac catheterisation
0.000 0.987 0.013
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.987 0.012
H43.8 Other disorders of vitreous body
0.000 0.988 0.012
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.000 0.988 0.012
I73 Other peripheral vascular diseases
0.000 0.989 0.011
H43.1 Vitreous haemorrhage
0.000 0.989 0.011
I86 Varicose veins of other sites
0.011 0.989 0.000
H43 Disorders of vitreous body
0.000 0.989 0.011
I86.1 Scrotal varices
0.011 0.989 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.000 0.991 0.009
N13 Obstructive and reflux uropathy
0.000 0.991 0.009
N13.8 Other obstructive and reflux uropathy
0.000 0.991 0.009
I86.2 Pelvic varices
0.009 0.991 0.000
N13.3 Other and unspecified hydronephrosis
0.000 0.991 0.009
H43.3 Other vitreous opacities
0.000 0.991 0.009
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
0.000 0.991 0.009
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.000 0.991 0.009
H43.9 Disorder of vitreous body, unspecified
0.000 0.991 0.009
I86.3 Vulval varices
0.008 0.992 0.000
H43.2 Crystalline deposits in vitreous body
0.000 0.992 0.008
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.000 0.992 0.008
J98.1 Pulmonary collapse
0.000 0.992 0.008
I86.0 Sublingual varices
0.008 0.992 0.000
I78.0 Hereditary haemorrhagic telangiectasia
0.001 0.992 0.008
I78.1 Naevus, nonneoplastic
0.000 0.992 0.008
N13.5 Kinking and stricture of ureter without hydronephrosis
0.000 0.992 0.008
Z95.2 Presence of prosthetic heart valve
0.000 0.992 0.008
H43.0 Vitreous prolapse
0.000 0.992 0.008
I86.8 Varicose veins of other specified sites
0.008 0.992 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.000 0.992 0.008
D11.0 Parotid gland
0.000 0.992 0.008
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.993 0.007
I73.8 Other specified peripheral vascular diseases
0.000 0.993 0.007
Z95.3 Presence of xenogenic heart valve
0.000 0.993 0.007
N13.6 Pyonephrosis
0.000 0.993 0.007
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
0.000 0.993 0.007
I27.2 Other secondary pulmonary hypertension
0.001 0.993 0.006
Z95.8 Presence of other cardiac and vascular implants and grafts
0.000 0.993 0.007
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
0.000 0.993 0.007
M62.89 Other specified disorders of muscle (Site unspecified)
0.007 0.993 0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
0.000 0.993 0.007
M62.88 Other specified disorders of muscle (Other)
0.007 0.993 0.000
G47 Sleep disorders
0.007 0.993 0.000
M62.8 Other specified disorders of muscle
0.006 0.993 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.000 0.994 0.006
K51.0 Ulcerative (chronic) enterocolitis
0.000 0.994 0.006
M62.82 Other specified disorders of muscle (Upper arm)
0.006 0.994 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.000 0.994 0.006
Q54.0 Hypospadias, balanic
0.006 0.994 0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
0.000 0.994 0.006
J32.2 Chronic ethmoidal sinusitis
0.000 0.994 0.006
J32.4 Chronic pansinusitis
0.000 0.994 0.006
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium
0.000 0.994 0.006
J32 Chronic sinusitis
0.000 0.994 0.006
M62.87 Other specified disorders of muscle (Ankle and foot)
0.005 0.994 0.000
Z95.4 Presence of other heart-valve replacement
0.000 0.994 0.006
I95.9 Hypotension, unspecified
0.000 0.995 0.005
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium
0.000 0.995 0.005
M62.83 Other specified disorders of muscle (Forearm)
0.005 0.995 0.000
Q54 Hypospadias
0.005 0.995 0.000
N13.4 Hydroureter
0.000 0.995 0.005
Q54.9 Hypospadias, unspecified
0.005 0.995 0.000
R07.4 Chest pain, unspecified
0.000 0.995 0.005
M62.84 Other specified disorders of muscle (Hand)
0.005 0.995 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.005 0.995 0.000
G47.9 Sleep disorder, unspecified
0.005 0.995 0.000
J32.0 Chronic maxillary sinusitis
0.000 0.995 0.005
M62 Other disorders of muscle
0.005 0.995 0.000
G47.2 Disorders of the sleep-wake schedule
0.005 0.995 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.000 0.995 0.005
J32.3 Chronic sphenoidal sinusitis
0.000 0.995 0.005
J32.1 Chronic frontal sinusitis
0.000 0.995 0.005
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.995 0.005
N76.0 Acute vaginitis
0.000 0.995 0.005
Q54.1 Hypospadias, penile
0.004 0.996 0.000
D13.1 Stomach
0.000 0.996 0.004
Z92.4 Personal history of major surgery, not elsewhere classified
0.000 0.996 0.004
M62.80 Other specified disorders of muscle (Multiple sites)
0.004 0.996 0.000
H83.0 Labyrinthitis
0.004 0.996 0.000
M62.1 Other rupture of muscle (nontraumatic)
0.004 0.996 0.000
J32.9 Chronic sinusitis, unspecified
0.000 0.996 0.004
M62.85 Other specified disorders of muscle (Pelvic region and thigh)
0.004 0.996 0.000
D11 Benign neoplasm of major salivary glands
0.000 0.996 0.004
H81.1 Benign paroxysmal vertigo
0.004 0.996 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.004 0.996 0.000
Q54.8 Other hypospadias
0.004 0.996 0.000
Q54.4 Congenital chordee
0.004 0.996 0.000
Q54.3 Hypospadias, perineal
0.004 0.996 0.000
Q54.2 Hypospadias, penoscrotal
0.004 0.996 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.004 0.996 0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus
0.004 0.996 0.000
S70.9 Superficial injury of hip and thigh, unspecified
0.000 0.996 0.004
G47.4 Narcolepsy and cataplexy
0.004 0.996 0.000
N76.2 Acute vulvitis
0.000 0.996 0.004
C71.1 Frontal lobe
0.000 0.996 0.004
M62.11 Other rupture of muscle (nontraumatic) (Shoulder region)
0.004 0.996 0.000
M62.86 Other specified disorders of muscle (Lower leg)
0.004 0.996 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.996 0.004
R61.9 Hyperhidrosis, unspecified
0.000 0.996 0.004
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.004 0.996 0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified
0.004 0.996 0.000
N76 Other inflammation of vagina and vulva
0.000 0.996 0.004
D11.7 Other major salivary glands
0.000 0.996 0.004
O26.9 Pregnancy-related condition, unspecified
0.004 0.996 0.000
G47.8 Other sleep disorders
0.004 0.996 0.000
H81.0 Meniere's disease
0.004 0.996 0.000
M62.9 Disorder of muscle, unspecified
0.004 0.996 0.000
M62.0 Diastasis of muscle
0.004 0.996 0.000
J32.8 Other chronic sinusitis
0.000 0.996 0.004
M62.4 Contracture of muscle
0.004 0.996 0.000
M62.3 Immobility syndrome (paraplegic)
0.004 0.996 0.000
M62.2 Ischaemic infarction of muscle
0.004 0.996 0.000
C71.0 Cerebrum, except lobes and ventricles
0.000 0.996 0.004
C71 Malignant neoplasm of brain
0.000 0.996 0.004
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.996 0.004
E80.4 Gilbert's syndrome
0.004 0.996 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.000 0.996 0.004
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.996 0.003
K86.8 Other specified diseases of pancreas
0.000 0.996 0.003
M62.81 Other specified disorders of muscle (Shoulder region)
0.003 0.997 0.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.997 0.003
S12.70 Multiple fractures of cervical spine (closed)
0.000 0.997 0.003
N76.4 Abscess of vulva
0.000 0.997 0.003
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.997 0.003
M62.19 Other rupture of muscle (nontraumatic) (Site unspecified)
0.003 0.997 0.000
M62.18 Other rupture of muscle (nontraumatic) (Other)
0.003 0.997 0.000
M62.17 Other rupture of muscle (nontraumatic) (Ankle and foot)
0.003 0.997 0.000
M62.16 Other rupture of muscle (nontraumatic) (Lower leg)
0.003 0.997 0.000
M62.15 Other rupture of muscle (nontraumatic) (Pelvic region and thigh)
0.003 0.997 0.000
M62.14 Other rupture of muscle (nontraumatic) (Hand)
0.003 0.997 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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