TreeWAS – Variant ID: rs13154291

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
E70-E90 Metabolic disorders	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
# Top node	1.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000
I30-I52 Other forms of heart disease	1.000	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.999	0.001
I35 Nonrheumatic aortic valve disorders	0.998	0.002
E86 Volume depletion	0.993	0.007
I05-I09 Chronic rheumatic heart diseases	0.992	0.008
Chapter XV Pregnancy, childbirth and the puerperium	0.990	0.010
I35.0 Aortic (valve) stenosis	0.990	0.010
E87 Other disorders of fluid, electrolyte and acid-base balance	0.990	0.010
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.988	0.012
E78.0 Pure hypercholesterolaemia	0.987	0.013
T81 Complications of procedures, not elsewhere classified	0.983	0.017
I08 Multiple valve diseases	0.979	0.021
Chapter VIII Diseases of the ear and mastoid process	0.978	0.022
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified	0.978	0.022
O60-O75 Complications of labour and delivery	0.978	0.022
Chapter VI Diseases of the nervous system	0.967	0.033
I50 Heart failure	0.966	0.034
Chapter X Diseases of the respiratory system	0.964	0.036
I08.1 Disorders of both mitral and tricuspid valves	0.962	0.038
E78.5 Hyperlipidaemia, unspecified	0.961	0.039
I51 Complications and ill-defined descriptions of heart disease	0.958	0.042
S10-S19 Injuries to the neck	0.950	0.050
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.944	0.056
J90-J94 Other diseases of pleura	0.936	0.064
O63 Long labour	0.935	0.065
I51.9 Heart disease, unspecified	0.933	0.067
S80-S89 Injuries to the knee and lower leg	0.931	0.069
E65-E68 Obesity and other hyperalimentation	0.931	0.069
J90 Pleural effusion, not elsewhere classified	0.927	0.073
I10-I15 Hypertensive diseases	0.926	0.074
D50-D53 Nutritional anaemias	0.925	0.075
I35.1 Aortic (valve) insufficiency	0.924	0.076
T81.3 Disruption of operation wound, not elsewhere classified	0.921	0.079
I47 Paroxysmal tachycardia	0.919	0.081
O63.1 Prolonged second stage (of labour)	0.914	0.086
S60-S69 Injuries to the wrist and hand	0.907	0.093
G30-G32 Other degenerative diseases of the nervous system	0.905	0.095
T66-T78 Other and unspecified effects of external causes	0.904	0.096
O61 Failed induction of labour	0.898	0.102
E20-E35 Disorders of other endocrine glands	0.895	0.105
I50.9 Heart failure, unspecified	0.892	0.108
D51 Vitamin B12 deficiency anaemia	0.890	0.110
I31 Other diseases of pericardium	0.887	0.113
E87.0 Hyperosmolality and hypernatraemia	0.886	0.114
E87.2 Acidosis	0.884	0.116
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.882	0.118
E66 Obesity	0.881	0.119
I50.1 Left ventricular failure	0.878	0.122
H90-H95 Other disorders of ear	0.873	0.127
T36-T50 Poisoning by drugs, medicaments and biological substances	0.871	0.129
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.870	0.130
E78.1 Pure hyperglyceridaemia	0.868	0.132
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.866	0.134
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.866	0.134
O20-O29 Other maternal disorders predominantly related to pregnancy	0.865	0.135
O85-O92 Complications predominantly related to the puerperium	0.863	0.137
I70-I79 Diseases of arteries, arterioles and capillaries	0.862	0.138
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.861	0.139
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.858	0.142
J95-J99 Other diseases of the respiratory system	0.858	0.142
T79-T79 Certain early complications of trauma	0.857	0.143
I37 Pulmonary valve disorders	0.856	0.144
Chapter XX External causes of morbidity and mortality	0.856	0.144
S19 Other and unspecified injuries of neck	0.856	0.144
J80-J84 Other respiratory diseases principally affecting the interstitium	0.855	0.145
T85 Complications of other internal prosthetic devices, implants and grafts	0.852	0.148
S62 Fracture at wrist and hand level	0.850	0.150
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.845	0.155
I46 Cardiac arrest	0.844	0.156
H65-H75 Diseases of middle ear and mastoid	0.843	0.157
E87.1 Hypo-osmolality and hyponatraemia	0.842	0.158
O61.0 Failed medical induction of labour	0.841	0.159
I95-I99 Other and unspecified disorders of the circulatory system	0.840	0.160
T78 Adverse effects, not elsewhere classified	0.840	0.160
O73 Retained placenta and membranes, without haemorrhage	0.839	0.161
H80-H83 Diseases of inner ear	0.839	0.161
E87.5 Hyperkalaemia	0.832	0.168
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.829	0.171
S40-S49 Injuries to the shoulder and upper arm	0.827	0.173
D50 Iron deficiency anaemia	0.826	0.174
I47.1 Supraventricular tachycardia	0.825	0.175
I07 Rheumatic tricuspid valve diseases	0.821	0.179
I08.2 Disorders of both aortic and tricuspid valves	0.819	0.181
G80-G83 Cerebral palsy and other paralytic syndromes	0.817	0.183
J09-J18 Influenza and pneumonia	0.814	0.186
H60-H62 Diseases of external ear	0.814	0.186
I31.9 Disease of pericardium, unspecified	0.812	0.188
T20-T25 Burns and corrosions of external body surface, specified by site	0.811	0.189
H92 Otalgia and effusion of ear	0.811	0.189
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.810	0.190
I10 Essential (primary) hypertension	0.805	0.195
G31.9 Degenerative disease of nervous system, unspecified	0.802	0.198
S83.2 Tear of meniscus, current	0.802	0.198
E87.6 Hypokalaemia	0.801	0.199
O71 Other obstetric trauma	0.801	0.199
T86 Failure and rejection of transplanted organs and tissues	0.798	0.202
E40-E46 Malnutrition	0.797	0.203
S86 Injury of muscle and tendon at lower leg level	0.796	0.204
I08.0 Disorders of both mitral and aortic valves	0.795	0.205
J81 Pulmonary oedema	0.793	0.207
E78.2 Mixed hyperlipidaemia	0.789	0.210
E21.3 Hyperparathyroidism, unspecified	0.789	0.211
S19.9 Unspecified injury of neck	0.788	0.212
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.787	0.213
I05 Rheumatic mitral valve diseases	0.786	0.214
J98 Other respiratory disorders	0.786	0.214
O72 Postpartum haemorrhage	0.784	0.216
I35.8 Other aortic valve disorders	0.784	0.216
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.780	0.220
E66.9 Obesity, unspecified	0.779	0.221
I33 Acute and subacute endocarditis	0.778	0.222
S62.2 Fracture of first metacarpal bone	0.775	0.225
O47 False labour	0.774	0.226
I35.2 Aortic (valve) stenosis with insufficiency	0.771	0.229
I51.7 Cardiomegaly	0.770	0.230
O24 Diabetes mellitus in pregnancy	0.768	0.232
S42 Fracture of shoulder and upper arm	0.768	0.232
S10 Superficial injury of neck	0.765	0.235
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.765	0.235
T78.4 Allergy, unspecified	0.762	0.238
G62 Other polyneuropathies	0.760	0.240
G31.2 Degeneration of nervous system due to alcohol	0.760	0.240
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.760	0.240
S14 Injury of nerves and spinal cord at neck level	0.757	0.242
T81.9 Unspecified complication of procedure	0.757	0.243
E78.4 Other hyperlipidaemia	0.756	0.244
H74 Other disorders of middle ear and mastoid	0.756	0.244
T79 Certain early complications of trauma, not elsewhere classified	0.755	0.245
S30 Superficial injury of abdomen, lower back and pelvis	0.755	0.245
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.754	0.246
I37.1 Pulmonary valve insufficiency	0.753	0.247
J60-J70 Lung diseases due to external agents	0.751	0.249
I11 Hypertensive heart disease	0.748	0.252
E50-E64 Other nutritional deficiencies	0.746	0.254
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.743	0.256
H92.0 Otalgia	0.741	0.259
J18 Pneumonia, organism unspecified	0.740	0.260
D50.9 Iron deficiency anaemia, unspecified	0.740	0.260
I47.9 Paroxysmal tachycardia, unspecified	0.739	0.261
T81.7 Vascular complications following a procedure, not elsewhere classified	0.739	0.261
I34 Nonrheumatic mitral valve disorders	0.732	0.268
T87 Complications peculiar to reattachment and amputation	0.731	0.269
T88 Other complications of surgical and medical care, not elsewhere classified	0.731	0.269
G20-G26 Extrapyramidal and movement disorders	0.730	0.270
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.730	0.270
O70 Perineal laceration during delivery	0.730	0.270
I30 Acute pericarditis	0.730	0.270
X20-X29 Contact with venomous animals and plants	0.727	0.273
H80 Otosclerosis	0.727	0.273
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.725	0.274
I51.6 Cardiovascular disease, unspecified	0.725	0.275
I95 Hypotension	0.724	0.276
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.722	0.278
S62.20 Fracture of first metacarpal bone (closed)	0.721	0.279
S42.2 Fracture of upper end of humerus	0.721	0.279
I12 Hypertensive renal disease	0.719	0.281
G90-G99 Other disorders of the nervous system	0.717	0.283
E85 Amyloidosis	0.717	0.283
E84 Cystic fibrosis	0.717	0.283
E79 Disorders of purine and pyrimidine metabolism	0.717	0.283
E77 Disorders of glycoprotein metabolism	0.717	0.283
E76 Disorders of glycosaminoglycan metabolism	0.717	0.283
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.717	0.283
E74 Other disorders of carbohydrate metabolism	0.717	0.283
E73 Lactose intolerance	0.717	0.283
E72 Other disorders of amino-acid metabolism	0.717	0.283
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.717	0.283
E70 Disorders of aromatic amino-acid metabolism	0.717	0.283
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.717	0.283
I00-I02 Acute rheumatic fever	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
I52 Other heart disorders in diseases classified elsewhere	0.717	0.283
I48 Atrial fibrillation and flutter	0.717	0.283
I43 Cardiomyopathy in diseases classified elsewhere	0.717	0.283
I41 Myocarditis in diseases classified elsewhere	0.717	0.283
I40 Acute myocarditis	0.717	0.283
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.717	0.283
I32 Pericarditis in diseases classified elsewhere	0.717	0.283
J18.9 Pneumonia, unspecified	0.717	0.283
E78.6 Lipoprotein deficiency	0.716	0.284
E78.3 Hyperchylomicronaemia	0.716	0.284
E78.8 Other disorders of lipoprotein metabolism	0.716	0.284
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.715	0.285
S66 Injury of muscle and tendon at wrist and hand level	0.715	0.285
I72 Other aneurysm	0.715	0.285
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.714	0.286
D55-D59 Haemolytic anaemias	0.714	0.286
H71 Cholesteatoma of middle ear	0.714	0.286
E66.8 Other obesity	0.714	0.286
T59 Toxic effect of other gases, fumes and vapours	0.713	0.287
T93 Sequelae of injuries of lower limb	0.712	0.288
O90 Complications of the puerperium, not elsewhere classified	0.712	0.288
E27 Other disorders of adrenal gland	0.712	0.288
G70-G73 Diseases of myoneural junction and muscle	0.711	0.288
H61 Other disorders of external ear	0.711	0.289
I09 Other rheumatic heart diseases	0.711	0.289
I06 Rheumatic aortic valve diseases	0.711	0.289
O64 Obstructed labour due to malposition and malpresentation of foetus	0.711	0.289
O47.1 False labour at or after 37 completed weeks of gestation	0.711	0.289
I15 Secondary hypertension	0.710	0.290
G50-G59 Nerve, nerve root and plexus disorders	0.710	0.290
E87.4 Mixed disorder of acid-base balance	0.709	0.290
E87.3 Alkalosis	0.709	0.290
W50-W64 Exposure to animate mechanical forces	0.708	0.292
H81 Disorders of vestibular function	0.708	0.292
I74 Arterial embolism and thrombosis	0.708	0.292
E66.0 Obesity due to excess calories	0.708	0.292
I46.0 Cardiac arrest with successful resuscitation	0.707	0.293
E22 Hyperfunction of pituitary gland	0.707	0.293
D50.8 Other iron deficiency anaemias	0.707	0.293
O73.0 Retained placenta, without haemorrhage	0.706	0.294
I47.0 Reentry ventricular arrhythmia	0.706	0.294
T81.6 Acute reaction to foreign substance accidentally left during a procedure	0.705	0.295
T81.1 Shock during or resulting from a procedure, not elsewhere classified	0.705	0.295
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.704	0.296
O68 Labour and delivery complicated by foetal stress [distress]	0.704	0.296
I08.9 Multiple valve disease, unspecified	0.702	0.298
S64 Injury of nerves at wrist and hand level	0.702	0.298
O74 Complications of anaesthesia during labour and delivery	0.701	0.299
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.701	0.299
O65 Obstructed labour due to maternal pelvic abnormality	0.701	0.299
O60 Preterm delivery	0.701	0.299
O87 Venous complications in the puerperium	0.701	0.299
T46 Poisoning by agents primarily affecting the cardiovascular system	0.700	0.300
I51.0 Cardiac septal defect, acquired	0.700	0.300
I07.1 Tricuspid insufficiency	0.698	0.302
H93 Other disorders of ear, not elsewhere classified	0.697	0.303
J98.1 Pulmonary collapse	0.697	0.303
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.696	0.304
O66 Other obstructed labour	0.696	0.304
G82 Paraplegia and tetraplegia	0.695	0.305
G83 Other paralytic syndromes	0.695	0.305
D80-D89 Certain disorders involving the immune mechanism	0.695	0.305
E66.2 Extreme obesity with alveolar hypoventilation	0.693	0.307
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.691	0.309
I36 Nonrheumatic tricuspid valve disorders	0.690	0.310
S68 Traumatic amputation of wrist and hand	0.689	0.311
I95.9 Hypotension, unspecified	0.689	0.311
O26 Maternal care for other conditions predominantly related to pregnancy	0.689	0.311
S42.20 Fracture of upper end of humerus (closed)	0.688	0.312
I51.5 Myocardial degeneration	0.687	0.313
I51.3 Intracardiac thrombosis, not elsewhere classified	0.687	0.313
I51.2 Rupture of papillary muscle, not elsewhere classified	0.687	0.313
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.687	0.313
O34 Maternal care for known or suspected abnormality of pelvic organs	0.687	0.313
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.687	0.313
I77 Other disorders of arteries and arterioles	0.686	0.314
T86.8 Failure and rejection of other transplanted organs and tissues	0.685	0.315
I50.0 Congestive heart failure	0.685	0.315
I98 Other disorders of circulatory system in diseases classified elsewhere	0.683	0.317
S62.7 Multiple fractures of fingers	0.683	0.317
O70.1 Second degree perineal laceration during delivery	0.682	0.318
G63 Polyneuropathy in diseases classified elsewhere	0.682	0.318
H73 Other disorders of tympanic membrane	0.681	0.319
S17 Crushing injury of neck	0.681	0.319
S15 Injury of blood vessels at neck level	0.681	0.319
S11 Open wound of neck	0.681	0.319
S18 Traumatic amputation at neck level	0.681	0.319
S16 Injury of muscle and tendon at neck level	0.681	0.319
O47.0 False labour before 37 completed weeks of gestation	0.681	0.319
S82 Fracture of lower leg, including ankle	0.679	0.321
E78.9 Disorder of lipoprotein metabolism, unspecified	0.679	0.321
T80 Complications following infusion, transfusion and therapeutic injection	0.679	0.321
T63 Toxic effect of contact with venomous animals	0.679	0.321
O23 Infections of genito-urinary tract in pregnancy	0.679	0.321
T79.3 Post-traumatic wound infection, not elsewhere classified	0.678	0.322
I51.4 Myocarditis, unspecified	0.678	0.322
J93 Pneumothorax	0.677	0.323
O48 Prolonged pregnancy	0.673	0.327
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.673	0.327
T92 Sequelae of injuries of upper limb	0.672	0.328
Y60-Y69 Misadventures to patients during surgical and medical care	0.672	0.328
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.671	0.329
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.671	0.329
O72.1 Other immediate postpartum haemorrhage	0.670	0.330
O63.2 Delayed delivery of second twin, triplet, etc.	0.670	0.330
T91 Sequelae of injuries of neck and trunk	0.670	0.330
T78.0 Anaphylactic shock due to adverse food reaction	0.669	0.331
S90-S99 Injuries to the ankle and foot	0.668	0.332
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.668	0.332
G00-G09 Inflammatory diseases of the central nervous system	0.668	0.332
S88 Traumatic amputation of lower leg	0.667	0.332
S87 Crushing injury of lower leg	0.667	0.332
S85 Injury of blood vessels at lower leg level	0.667	0.332
S84 Injury of nerves at lower leg level	0.667	0.332
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.668	0.332
E67 Other hyperalimentation	0.667	0.333
E68 Sequelae of hyperalimentation	0.667	0.333
E65 Localised adiposity	0.667	0.333
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.667	0.333
T78.2 Anaphylactic shock, unspecified	0.666	0.334
I38 Endocarditis, valve unspecified	0.666	0.334
I13 Hypertensive heart and renal disease	0.664	0.336
D53 Other nutritional anaemias	0.663	0.336
H92.1 Otorrhoea	0.663	0.337
O71.8 Other specified obstetric trauma	0.663	0.337
V10-V19 Pedal cyclist injured in transport accident	0.663	0.337
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.663	0.337
I70 Atherosclerosis	0.661	0.339
E34 Other endocrine disorders	0.660	0.340
E24 Cushing's syndrome	0.660	0.340
T56 Toxic effect of metals	0.660	0.340
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.660	0.340
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.659	0.341
S60 Superficial injury of wrist and hand	0.658	0.342
V20-V29 Motorcycle rider injured in transport accident	0.658	0.342
V80-V89 Other land transport accidents	0.658	0.342
S13.4 Sprain and strain of cervical spine	0.657	0.342
D52 Folate deficiency anaemia	0.657	0.343
T36 Poisoning by systemic antibiotics	0.656	0.344
J00-J06 Acute upper respiratory infections	0.656	0.344
H61.8 Other specified disorders of external ear	0.656	0.344
S83.6 Sprain and strain of other and unspecified parts of knee	0.655	0.345
O45 Premature separation of placenta [abruptio placentae]	0.654	0.346
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.653	0.347
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.653	0.347
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.653	0.347
T51 Toxic effect of alcohol	0.652	0.348
E46 Unspecified protein-energy malnutrition	0.652	0.348
I08.8 Other multiple valve diseases	0.652	0.348
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.652	0.348
X50-X57 Overexertion, travel and privation	0.651	0.349
S65 Injury of blood vessels at wrist and hand level	0.650	0.350
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.649	0.351
T75 Effects of other external causes	0.648	0.351
T74 Maltreatment syndromes	0.648	0.351
T73 Effects of other deprivation	0.648	0.351
T70 Effects of air pressure and water pressure	0.648	0.351
T69 Other effects of reduced temperature	0.648	0.351
T67 Effects of heat and light	0.648	0.351
T71 Asphyxiation	0.648	0.351
T66 Unspecified effects of radiation	0.648	0.351
I73 Other peripheral vascular diseases	0.648	0.352
I46.9 Cardiac arrest, unspecified	0.648	0.352
S80 Superficial injury of lower leg	0.647	0.353
H80.9 Otosclerosis, unspecified	0.646	0.354
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.646	0.354
E80 Disorders of porphyrin and bilirubin metabolism	0.646	0.354
S67 Crushing injury of wrist and hand	0.646	0.354
O80-O84 Delivery	0.646	0.354
S00-S09 Injuries to the head	0.645	0.355
O61.9 Failed induction of labour, unspecified	0.644	0.356
O61.8 Other failed induction of labour	0.644	0.356
O61.1 Failed instrumental induction of labour	0.644	0.356
O24.4 Diabetes mellitus arising in pregnancy	0.643	0.357
O86 Other puerperal infections	0.642	0.357
S62.6 Fracture of other finger	0.642	0.358
E35 Disorders of endocrine glands in diseases classified elsewhere	0.642	0.358
E32 Diseases of thymus	0.642	0.358
E31 Polyglandular dysfunction	0.642	0.358
E30 Disorders of puberty, not elsewhere classified	0.642	0.358
E26 Hyperaldosteronism	0.642	0.358
E25 Adrenogenital disorders	0.642	0.358
E20 Hypoparathyroidism	0.642	0.358
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.641	0.359
J95 Postprocedural respiratory disorders, not elsewhere classified	0.640	0.360
J94 Other pleural conditions	0.639	0.361
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.639	0.361
D51.8 Other vitamin B12 deficiency anaemias	0.638	0.361
D51.3 Other dietary vitamin B12 deficiency anaemia	0.638	0.361
D51.2 Transcobalamin II deficiency	0.638	0.361
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.638	0.361
S32 Fracture of lumbar spine and pelvis	0.637	0.363
G60 Hereditary and idiopathic neuropathy	0.637	0.363
H70 Mastoiditis and related conditions	0.637	0.363
G62.1 Alcoholic polyneuropathy	0.637	0.363
I31.8 Other specified diseases of pericardium	0.636	0.364
I31.2 Haemopericardium, not elsewhere classified	0.636	0.364
I31.1 Chronic constrictive pericarditis	0.636	0.364
I31.0 Chronic adhesive pericarditis	0.636	0.364
X23 Contact with hornets, wasps and bees	0.635	0.365
X58-X59 Accidental exposure to other and unspecified factors	0.635	0.365
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.635	0.365
J84 Other interstitial pulmonary diseases	0.634	0.366
T68 Hypothermia	0.634	0.366
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.634	0.366
O30 Multiple gestation	0.633	0.366
T94 Sequelae of injuries involving multiple and unspecified body regions	0.633	0.367
H74.4 Polyp of middle ear	0.633	0.367
S10.9 Superficial injury of neck, part unspecified	0.633	0.367
S62.3 Fracture of other metacarpal bone	0.632	0.368
S83.7 Injury to multiple structures of knee	0.632	0.368
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.632	0.368
S83.3 Tear of articular cartilage of knee, current	0.632	0.368
S83.1 Dislocation of knee	0.632	0.368
S83.0 Dislocation of patella	0.632	0.368
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.632	0.368
E66.1 Drug-induced obesity	0.631	0.368
I47.2 Ventricular tachycardia	0.631	0.369
X10-X19 Contact with heat and hot substances	0.630	0.370
G62.9 Polyneuropathy, unspecified	0.629	0.371
G24 Dystonia	0.629	0.371
H94 Other disorders of ear in diseases classified elsewhere	0.626	0.374
S62.4 Multiple fractures of metacarpal bones	0.625	0.375
S20-S29 Injuries to the thorax	0.625	0.375
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.624	0.375
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.624	0.375
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.624	0.375
T41 Poisoning by anaesthetics and therapeutic gases	0.624	0.375
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.624	0.375
S12 Fracture of neck	0.624	0.376
T65 Toxic effect of other and unspecified substances	0.624	0.376
T62 Toxic effect of other noxious substances eaten as food	0.624	0.376
T61 Toxic effect of noxious substances eaten as seafood	0.624	0.376
T60 Toxic effect of pesticides	0.624	0.376
T57 Toxic effect of other inorganic substances	0.624	0.376
T54 Toxic effect of corrosive substances	0.624	0.376
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.624	0.376
T52 Toxic effect of organic solvents	0.624	0.376
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.624	0.376
T58 Toxic effect of carbon monoxide	0.624	0.376
T55 Toxic effect of soaps and detergents	0.624	0.376
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.624	0.376
H81.0 Meniere's disease	0.623	0.377
G31.8 Other specified degenerative diseases of nervous system	0.623	0.377
T81.4 Infection following a procedure, not elsewhere classified	0.623	0.377
S86.8 Injury of other muscles and tendons at lower leg level	0.622	0.378
T21 Burn and corrosion of trunk	0.622	0.378
T39.1 4-Aminophenol derivatives	0.621	0.379
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.621	0.379
G31.1 Senile degeneration of brain, not elsewhere classified	0.621	0.379
G31.0 Circumscribed brain atrophy	0.621	0.379
I11.9 Hypertensive heart disease without (congestive) heart failure	0.621	0.379
O29 Complications of anaesthesia during pregnancy	0.620	0.379
O28 Abnormal findings on antenatal screening of mother	0.620	0.379
O22 Venous complications in pregnancy	0.620	0.379
O25 Malnutrition in pregnancy	0.620	0.379
H66 Suppurative and unspecified otitis media	0.621	0.379
J98.9 Respiratory disorder, unspecified	0.620	0.380
S14.1 Other and unspecified injuries of cervical spinal cord	0.619	0.380
O92 Other disorders of breast and lactation associated with childbirth	0.619	0.381
O91 Infections of breast associated with childbirth	0.619	0.381
O89 Complications of anaesthesia during the puerperium	0.619	0.381
O88 Obstetric embolism	0.619	0.381
O85 Puerperal sepsis	0.619	0.381
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.619	0.381
I33.0 Acute and subacute infective endocarditis	0.619	0.381
E87.7 Fluid overload	0.619	0.381
S62.5 Fracture of thumb	0.619	0.381
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.619	0.381
S70-S79 Injuries to the hip and thigh	0.618	0.382
O63.9 Long labour, unspecified	0.618	0.382
O21 Excessive vomiting in pregnancy	0.618	0.382
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.617	0.383
S37 Injury of urinary and pelvic organs	0.617	0.383
S36 Injury of intra-abdominal organs	0.617	0.383
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.617	0.383
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.617	0.383
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.617	0.383
S31 Open wound of abdomen, lower back and pelvis	0.617	0.383
I31.3 Pericardial effusion (noninflammatory)	0.617	0.383
T23 Burn and corrosion of wrist and hand	0.617	0.383
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.617	0.383
T98 Sequelae of other and unspecified effects of external causes	0.616	0.384
T15-T19 Effects of foreign body entering through natural orifice	0.616	0.384
J15 Bacterial pneumonia, not elsewhere classified	0.616	0.384
T95 Sequelae of burns, corrosions and frostbite	0.615	0.384
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.615	0.384
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.615	0.384
X40-X49 Accidental poisoning by and exposure to noxious substances	0.615	0.385
J96 Respiratory failure, not elsewhere classified	0.615	0.385
Chapter XXII Codes for special purposes	0.614	0.386
I05.1 Rheumatic mitral insufficiency	0.614	0.386
I37.9 Pulmonary valve disorder, unspecified	0.614	0.386
I37.8 Other pulmonary valve disorders	0.614	0.386
I37.2 Pulmonary valve stenosis with insufficiency	0.614	0.386
I37.0 Pulmonary valve stenosis	0.614	0.386
Y35-Y36 Legal intervention and operations of war	0.614	0.386
Y10-Y34 Event of undetermined intent	0.614	0.386
Y00-Y09 Assault	0.614	0.386
X85-X99 Assault	0.614	0.386
X30-X39 Exposure to forces of nature	0.614	0.386
X00-X09 Exposure to smoke, fire and flames	0.614	0.386
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.614	0.386
W75-W84 Other accidental threats to breathing	0.614	0.386
W65-W74 Accidental drowning and submersion	0.614	0.386
V98-V99 Other and unspecified transport accidents	0.614	0.386
V95-V97 Air and space transport accidents	0.614	0.386
V90-V94 Water transport accidents	0.614	0.386
V70-V79 Bus occupant injured in transport accident	0.614	0.386
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.614	0.386
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.614	0.386
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.614	0.386
V01-V09 Pedestrian injured in transport accident	0.614	0.386
H95.1 Other disorders following mastoidectomy	0.614	0.386
S19.8 Other specified injuries of neck	0.613	0.386
S19.7 Multiple injuries of neck	0.613	0.386
J82 Pulmonary eosinophilia, not elsewhere classified	0.613	0.387
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.613	0.387
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.613	0.387
S62.8 Fracture of other and unspecified parts of wrist and hand	0.612	0.388
I35.9 Aortic valve disorder, unspecified	0.611	0.388

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations