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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs11743835
log Bayes Factor = 13.1859
Chromosome 5   position 111,979,658  (GRCh37) Explore rs11743835 on Ensembl!
Variant rs11743835 is part of Cluster X0258

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter II Neoplasms
0.999 0.001 0.000
Chapter V Mental and behavioural disorders
0.999 0.001 0.000
Chapter XIV Diseases of the genitourinary system
0.998 0.002 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.997 0.003 0.000
S60-S69 Injuries to the wrist and hand
0.995 0.005 0.000
I51 Complications and ill-defined descriptions of heart disease
0.995 0.005 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.994 0.006 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.992 0.008 0.000
I51.8 Other ill-defined heart diseases
0.991 0.009 0.000
N92 Excessive, frequent and irregular menstruation
0.989 0.011 0.000
H40-H42 Glaucoma
0.988 0.012 0.000
I60-I69 Cerebrovascular diseases
0.984 0.016 0.000
H30-H36 Disorders of choroid and retina
0.982 0.018 0.000
H40 Glaucoma
0.980 0.020 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.980 0.020 0.000
H35 Other retinal disorders
0.978 0.022 0.000
F10.1 Harmful use
0.974 0.026 0.000
N92.1 Excessive and frequent menstruation with irregular cycle
0.974 0.026 0.000
S64 Injury of nerves at wrist and hand level
0.971 0.029 0.000
C15-C26 Malignant neoplasms of digestive organs
0.966 0.034 0.000
H35.3 Degeneration of macula and posterior pole
0.966 0.034 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.966 0.034 0.000
N84 Polyp of female genital tract
0.964 0.036 0.000
I44 Atrioventricular and left bundle-branch block
0.963 0.037 0.000
N87 Dysplasia of cervix uteri
0.958 0.042 0.000
H40.1 Primary open-angle glaucoma
0.954 0.046 0.000
C18 Malignant neoplasm of colon
0.951 0.049 0.000
Chapter VI Diseases of the nervous system
0.951 0.049 0.000
I35 Nonrheumatic aortic valve disorders
0.950 0.050 0.000
S40-S49 Injuries to the shoulder and upper arm
0.950 0.050 0.000
Chapter I Certain infectious and parasitic diseases
0.942 0.058 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.939 0.061 0.000
Chapter VIII Diseases of the ear and mastoid process
0.937 0.063 0.000
N92.3 Ovulation bleeding
0.924 0.076 0.000
I45 Other conduction disorders
0.923 0.077 0.000
I69 Sequelae of cerebrovascular disease
0.919 0.081 0.000
I44.0 Atrioventricular block, first degree
0.917 0.083 0.000
S90-S99 Injuries to the ankle and foot
0.916 0.084 0.000
H55-H59 Other disorders of eye and adnexa
0.914 0.086 0.000
H40.0 Glaucoma suspect
0.914 0.086 0.000
N84.0 Polyp of corpus uteri
0.913 0.087 0.000
C77.1 Intrathoracic lymph nodes
0.910 0.090 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.906 0.094 0.000
D00-D09 In situ neoplasms
0.905 0.095 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.905 0.095 0.000
S42 Fracture of shoulder and upper arm
0.905 0.095 0.000
G90-G99 Other disorders of the nervous system
0.904 0.096 0.000
F10.0 Acute intoxication
0.899 0.101 0.000
S64.0 Injury of ulnar nerve at wrist and hand level
0.898 0.102 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.895 0.105 0.000
N17-N19 Renal failure
0.892 0.108 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.892 0.108 0.000
I05-I09 Chronic rheumatic heart diseases
0.890 0.110 0.000
N60-N64 Disorders of breast
0.890 0.110 0.000
I35.0 Aortic (valve) stenosis
0.887 0.113 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.885 0.115 0.000
N87.0 Mild cervical dysplasia
0.884 0.116 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.883 0.117 0.000
C51-C58 Malignant neoplasms of female genital organs
0.882 0.118 0.000
H65-H75 Diseases of middle ear and mastoid
0.879 0.121 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.872 0.128 0.000
N81 Female genital prolapse
0.870 0.130 0.000
C18.9 Colon, unspecified
0.869 0.131 0.000
I51.9 Heart disease, unspecified
0.866 0.134 0.000
B07 Viral warts
0.860 0.140 0.000
C18.5 Splenic flexure
0.859 0.141 0.000
H35.6 Retinal haemorrhage
0.859 0.141 0.000
G93 Other disorders of brain
0.857 0.143 0.000
C77.9 Lymph node, unspecified
0.856 0.144 0.000
S80-S89 Injuries to the knee and lower leg
0.856 0.144 0.000
F10.2 Dependence syndrome
0.853 0.147 0.000
N84.1 Polyp of cervix uteri
0.852 0.148 0.000
I44.7 Left bundle-branch block, unspecified
0.851 0.149 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.850 0.150 0.000
I61 Intracerebral haemorrhage
0.848 0.152 0.000
S42.3 Fracture of shaft of humerus
0.845 0.155 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.844 0.156 0.000
H40.2 Primary angle-closure glaucoma
0.843 0.157 0.000
C77.3 Axillary and upper limb lymph nodes
0.840 0.160 0.000
G30-G32 Other degenerative diseases of the nervous system
0.840 0.160 0.000
S64.4 Injury of digital nerve of other finger
0.838 0.162 0.000
H35.8 Other specified retinal disorders
0.836 0.164 0.000
I31 Other diseases of pericardium
0.827 0.173 0.000
S64.1 Injury of median nerve at wrist and hand level
0.826 0.173 0.000
I45.6 Preexcitation syndrome
0.825 0.175 0.000
G81 Hemiplegia
0.820 0.180 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.819 0.181 0.000
I67 Other cerebrovascular diseases
0.817 0.183 0.000
F10.3 Withdrawal state
0.814 0.186 0.000
F40 Phobic anxiety disorders
0.813 0.187 0.000
H55 Nystagmus and other irregular eye movements
0.812 0.188 0.000
I08 Multiple valve diseases
0.811 0.189 0.000
H66 Suppurative and unspecified otitis media
0.811 0.189 0.000
C43 Malignant melanoma of skin
0.811 0.189 0.000
I46 Cardiac arrest
0.809 0.191 0.000
H25-H28 Disorders of lens
0.809 0.191 0.000
N93 Other abnormal uterine and vaginal bleeding
0.808 0.192 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.806 0.194 0.000
S42.30 Fracture of shaft of humerus (closed)
0.802 0.198 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.802 0.198 0.000
F20 Schizophrenia
0.801 0.199 0.000
S65 Injury of blood vessels at wrist and hand level
0.800 0.200 0.000
N87.9 Dysplasia of cervix uteri, unspecified
0.800 0.200 0.000
Chapter XX External causes of morbidity and mortality
0.799 0.201 0.000
C18.7 Sigmoid colon
0.797 0.203 0.000
A30-A49 Other bacterial diseases
0.794 0.206 0.000
G93.3 Postviral fatigue syndrome
0.793 0.207 0.000
N18 Chronic renal failure
0.792 0.208 0.000
S69 Other and unspecified injuries of wrist and hand
0.790 0.210 0.000
N92.4 Excessive bleeding in the premenopausal period
0.790 0.210 0.000
N81.5 Vaginal enterocele
0.789 0.211 0.000
N63 Unspecified lump in breast
0.788 0.212 0.000
I42 Cardiomyopathy
0.787 0.213 0.000
I62 Other nontraumatic intracranial haemorrhage
0.786 0.214 0.000
I63 Cerebral infarction
0.786 0.214 0.000
N87.2 Severe cervical dysplasia, not elsewhere classified
0.785 0.215 0.000
N81.3 Complete uterovaginal prolapse
0.785 0.215 0.000
N25-N29 Other disorders of kidney and ureter
0.784 0.216 0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.783 0.217 0.000
N17 Acute renal failure
0.782 0.218 0.000
C18.3 Hepatic flexure
0.782 0.218 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.782 0.218 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.778 0.222 0.000
N81.8 Other female genital prolapse
0.778 0.222 0.000
D04 Carcinoma in situ of skin
0.778 0.222 0.000
H72 Perforation of tympanic membrane
0.776 0.224 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.775 0.225 0.000
G81.9 Hemiplegia, unspecified
0.774 0.226 0.000
H10-H13 Disorders of conjunctiva
0.771 0.229 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.771 0.229 0.000
C77.5 Intrapelvic lymph nodes
0.771 0.229 0.000
F40.2 Specific (isolated) phobias
0.770 0.230 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.767 0.233 0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level
0.766 0.234 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.765 0.235 0.000
B65-B83 Helminthiases
0.765 0.235 0.000
T79-T79 Certain early complications of trauma
0.763 0.237 0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level
0.761 0.239 0.000
H34 Retinal vascular occlusions
0.761 0.239 0.000
D03 Melanoma in situ
0.757 0.243 0.000
H16 Keratitis
0.756 0.244 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.755 0.245 0.000
S92 Fracture of foot, except ankle
0.753 0.247 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.752 0.248 0.000
S91 Open wound of ankle and foot
0.751 0.249 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.750 0.250 0.000
F99-F99 Unspecified mental disorder
0.750 0.250 0.000
I50 Heart failure
0.750 0.250 0.000
H57 Other disorders of eye and adnexa
0.749 0.251 0.000
G20-G26 Extrapyramidal and movement disorders
0.749 0.251 0.000
I36 Nonrheumatic tricuspid valve disorders
0.746 0.254 0.000
H20 Iridocyclitis
0.742 0.258 0.000
C50-C50 Malignant neoplasm of breast
0.741 0.259 0.000
F80-F89 Disorders of psychological development
0.740 0.260 0.000
H90-H95 Other disorders of ear
0.740 0.260 0.000
I35.8 Other aortic valve disorders
0.739 0.261 0.000
N88 Other noninflammatory disorders of cervix uteri
0.737 0.263 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.737 0.263 0.000
N92.5 Other specified irregular menstruation
0.736 0.264 0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level
0.735 0.264 0.000
N81.2 Incomplete uterovaginal prolapse
0.735 0.265 0.000
F60-F69 Disorders of adult personality and behaviour
0.735 0.265 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.734 0.266 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.734 0.266 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.734 0.266 0.000
I60 Subarachnoid haemorrhage
0.733 0.267 0.000
I45.1 Other and unspecified right bundle-branch block
0.733 0.267 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.732 0.268 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.732 0.268 0.000
N94.1 Dyspareunia
0.730 0.270 0.000
I31.3 Pericardial effusion (noninflammatory)
0.730 0.270 0.000
T66-T78 Other and unspecified effects of external causes
0.730 0.270 0.000
C79 Secondary malignant neoplasm of other sites
0.728 0.272 0.000
S42.1 Fracture of scapula
0.726 0.273 0.000
S82 Fracture of lower leg, including ankle
0.726 0.274 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.724 0.276 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.724 0.276 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.723 0.277 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.723 0.277 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.721 0.279 0.000
S99 Other and unspecified injuries of ankle and foot
0.721 0.279 0.000
I44.6 Other and unspecified fascicular block
0.720 0.279 0.000
I45.3 Trifascicular block
0.720 0.280 0.000
N18.4 Chronic kidney disease, stage 4
0.720 0.280 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.719 0.281 0.000
H25 Senile cataract
0.719 0.281 0.000
H18 Other disorders of cornea
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
N61 Inflammatory disorders of breast
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.716 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.283 0.000
S67 Crushing injury of wrist and hand
0.716 0.284 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.716 0.284 0.000
F70-F79 Mental retardation
0.716 0.284 0.000
N99-N99 Other disorders of the genitourinary system
0.716 0.284 0.000
G93.9 Disorder of brain, unspecified
0.715 0.284 0.000
C15 Malignant neoplasm of oesophagus
0.715 0.285 0.000
N98 Complications associated with artificial fertilisation
0.715 0.285 0.000
N91 Absent, scanty and rare menstruation
0.715 0.285 0.000
N82 Fistulae involving female genital tract
0.715 0.285 0.000
N96 Habitual aborter
0.715 0.285 0.000
S90 Superficial injury of ankle and foot
0.715 0.285 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.714 0.286 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.714 0.286 0.000
N20-N23 Urolithiasis
0.714 0.286 0.000
I51.6 Cardiovascular disease, unspecified
0.714 0.286 0.000
I51.5 Myocardial degeneration
0.714 0.286 0.000
I51.4 Myocarditis, unspecified
0.714 0.286 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.714 0.286 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.714 0.286 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.714 0.286 0.000
I51.0 Cardiac septal defect, acquired
0.714 0.286 0.000
N94.8 Other specified conditions associated with female genital organs and menstrual cycle
0.713 0.286 0.000
S40 Superficial injury of shoulder and upper arm
0.713 0.287 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.713 0.287 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.713 0.287 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.713 0.287 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.713 0.287 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.713 0.287 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.713 0.287 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.713 0.287 0.000
F11 Mental and behavioural disorders due to use of opioids
0.713 0.287 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.713 0.287 0.000
C56 Malignant neoplasm of ovary
0.712 0.288 0.000
H35.9 Retinal disorder, unspecified
0.712 0.288 0.000
C77.4 Inguinal and lower limb lymph nodes
0.712 0.288 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.711 0.289 0.000
F10.9 Unspecified mental and behavioural disorder
0.711 0.289 0.000
F10.8 Other mental and behavioural disorders
0.711 0.289 0.000
F10.7 Residual and late-onset psychotic disorder
0.711 0.289 0.000
F10.6 Amnesic syndrome
0.711 0.289 0.000
F10.5 Psychotic disorder
0.711 0.289 0.000
F10.4 Withdrawal state with delirium
0.711 0.289 0.000
I05 Rheumatic mitral valve diseases
0.711 0.289 0.000
Q60-Q64 Congenital malformations of the urinary system
0.711 0.289 0.000
N92.2 Excessive menstruation at puberty
0.709 0.291 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.709 0.291 0.000
H66.3 Other chronic suppurative otitis media
0.709 0.291 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.709 0.291 0.000
H42 Glaucoma in diseases classified elsewhere
0.709 0.291 0.000
H74 Other disorders of middle ear and mastoid
0.708 0.292 0.000
H53-H54 Visual disturbances and blindness
0.707 0.293 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.706 0.294 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.706 0.294 0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)
0.705 0.295 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.704 0.296 0.000
H31 Other disorders of choroid
0.704 0.296 0.000
H30 Chorioretinal inflammation
0.704 0.296 0.000
C77.8 Lymph nodes of multiple regions
0.703 0.296 0.000
N17.9 Acute renal failure, unspecified
0.704 0.296 0.000
G95 Other diseases of spinal cord
0.704 0.296 0.000
S64.3 Injury of digital nerve of thumb
0.703 0.297 0.000
H60-H62 Diseases of external ear
0.703 0.297 0.000
F20.9 Schizophrenia, unspecified
0.703 0.297 0.000
H40.8 Other glaucoma
0.703 0.297 0.000
H40.6 Glaucoma secondary to drugs
0.703 0.297 0.000
H40.4 Glaucoma secondary to eye inflammation
0.703 0.297 0.000
H40.3 Glaucoma secondary to eye trauma
0.703 0.297 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.702 0.298 0.000
N93.9 Abnormal uterine and vaginal bleeding, unspecified
0.702 0.298 0.000
I44.1 Atrioventricular block, second degree
0.702 0.298 0.000
I67.1 Cerebral aneurysm, nonruptured
0.702 0.298 0.000
H66.9 Otitis media, unspecified
0.701 0.299 0.000
C16 Malignant neoplasm of stomach
0.701 0.299 0.000
H35.7 Separation of retinal layers
0.701 0.299 0.000
H35.5 Hereditary retinal dystrophy
0.701 0.299 0.000
H35.2 Other proliferative retinopathy
0.701 0.299 0.000
H35.1 Retinopathy of prematurity
0.701 0.299 0.000
I61.8 Other intracerebral haemorrhage
0.701 0.299 0.000
G83 Other paralytic syndromes
0.699 0.301 0.000
N86 Erosion and ectropion of cervix uteri
0.699 0.301 0.000
C18.0 Caecum
0.698 0.302 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.698 0.302 0.000
I35.9 Aortic valve disorder, unspecified
0.697 0.303 0.000
S42.0 Fracture of clavicle
0.696 0.304 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.696 0.304 0.000
S64.9 Injury of unspecified nerve at wrist and hand level
0.696 0.304 0.000
S64.8 Injury of other nerves at wrist and hand level
0.696 0.304 0.000
S64.7 Injury of multiple nerves at wrist and hand level
0.696 0.304 0.000
S64.2 Injury of radial nerve at wrist and hand level
0.696 0.304 0.000
N00-N08 Glomerular diseases
0.695 0.305 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.694 0.305 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.693 0.307 0.000
C43.7 Malignant melanoma of lower limb, including hip
0.693 0.307 0.000
C21 Malignant neoplasm of anus and anal canal
0.693 0.307 0.000
C17 Malignant neoplasm of small intestine
0.693 0.307 0.000
C23 Malignant neoplasm of gallbladder
0.693 0.307 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.693 0.307 0.000
N84.9 Polyp of female genital tract, unspecified
0.691 0.309 0.000
N84.8 Polyp of other parts of female genital tract
0.691 0.309 0.000
N84.3 Polyp of vulva
0.691 0.309 0.000
I44.5 Left posterior fascicular block
0.691 0.309 0.000
I44.4 Left anterior fascicular block
0.691 0.309 0.000
I44.3 Other and unspecified atrioventricular block
0.691 0.309 0.000
I08.8 Other multiple valve diseases
0.690 0.310 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.689 0.311 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.689 0.311 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.688 0.312 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.687 0.312 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.685 0.315 0.000
I45.5 Other specified heart block
0.684 0.316 0.000
C54 Malignant neoplasm of corpus uteri
0.684 0.316 0.000
S60 Superficial injury of wrist and hand
0.684 0.316 0.000
N87.1 Moderate cervical dysplasia
0.684 0.316 0.000
C18.8 Overlapping lesion of colon
0.682 0.318 0.000
C18.1 Appendix
0.682 0.318 0.000
Q50-Q56 Congenital malformations of genital organs
0.681 0.319 0.000
S48 Traumatic amputation of shoulder and upper arm
0.681 0.319 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.681 0.319 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.681 0.319 0.000
S44 Injury of nerves at shoulder and upper arm level
0.681 0.319 0.000
S41 Open wound of shoulder and upper arm
0.681 0.319 0.000
S47 Crushing injury of shoulder and upper arm
0.681 0.319 0.000
G30 Alzheimer's disease
0.681 0.319 0.000
H35.0 Background retinopathy and retinal vascular changes
0.680 0.320 0.000
H69 Other disorders of Eustachian tube
0.679 0.321 0.000
H40.5 Glaucoma secondary to other eye disorders
0.679 0.321 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.679 0.321 0.000
C18.2 Ascending colon
0.678 0.322 0.000
S63.6 Sprain and strain of finger(s)
0.677 0.323 0.000
D05 Carcinoma in situ of breast
0.677 0.323 0.000
C43.4 Malignant melanoma of scalp and neck
0.676 0.323 0.000
C18.6 Descending colon
0.676 0.324 0.000
B99-B99 Other infectious diseases
0.675 0.325 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.675 0.325 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.675 0.325 0.000
B50-B64 Protozoal diseases
0.675 0.325 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.675 0.325 0.000
A80-A89 Viral infections of the central nervous system
0.675 0.325 0.000
A75-A79 Rickettsioses
0.675 0.325 0.000
A70-A74 Other diseases caused by chlamydiae
0.675 0.325 0.000
A65-A69 Other spirochaetal diseases
0.675 0.325 0.000
A20-A28 Certain zoonotic bacterial diseases
0.675 0.325 0.000
A15-A19 Tuberculosis
0.675 0.325 0.000
S66.8 Injury of other muscles and tendons at wrist and hand level
0.673 0.326 0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level
0.673 0.326 0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level
0.673 0.326 0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level
0.673 0.326 0.000
F30-F39 Mood [affective] disorders
0.673 0.327 0.000
N60 Benign mammary dysplasia
0.673 0.327 0.000
S80 Superficial injury of lower leg
0.672 0.328 0.000
C43.6 Malignant melanoma of upper limb, including shoulder
0.672 0.328 0.000
C64-C68 Malignant neoplasms of urinary tract
0.672 0.328 0.000
G96 Other disorders of central nervous system
0.671 0.328 0.000
F43 Reaction to severe stress, and adjustment disorders
0.671 0.329 0.000
I33 Acute and subacute endocarditis
0.671 0.329 0.000
I30 Acute pericarditis
0.671 0.329 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.671 0.329 0.000
Q00-Q07 Congenital malformations of the nervous system
0.670 0.329 0.000
N93.0 Postcoital and contact bleeding
0.670 0.330 0.000
H25.0 Senile incipient cataract
0.670 0.330 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.670 0.330 0.000
C44 Other malignant neoplasms of skin
0.669 0.331 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.669 0.331 0.000
S00-S09 Injuries to the head
0.669 0.331 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.668 0.331 0.000
D09 Carcinoma in situ of other and unspecified sites
0.668 0.332 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.667 0.333 0.000
I46.9 Cardiac arrest, unspecified
0.666 0.334 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.666 0.334 0.000
Chapter XXII Codes for special purposes
0.664 0.336 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.662 0.338 0.000
I50.0 Congestive heart failure
0.662 0.338 0.000
I45.8 Other specified conduction disorders
0.662 0.338 0.000
I45.4 Nonspecific intraventricular block
0.662 0.338 0.000
I45.2 Bifascicular block
0.662 0.338 0.000
I45.0 Right fascicular block
0.662 0.338 0.000
F20.0 Paranoid schizophrenia
0.661 0.339 0.000
S65.5 Injury of blood vessel(s) of other finger
0.660 0.340 0.000
A00-A09 Intestinal infectious diseases
0.660 0.340 0.000
S42.2 Fracture of upper end of humerus
0.660 0.340 0.000
S20-S29 Injuries to the thorax
0.660 0.340 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.659 0.341 0.000
C18.4 Transverse colon
0.659 0.341 0.000
G91 Hydrocephalus
0.658 0.341 0.000
H25.8 Other senile cataract
0.658 0.342 0.000
N84.2 Polyp of vagina
0.657 0.343 0.000
S98 Traumatic amputation of ankle and foot
0.657 0.343 0.000
S97 Crushing injury of ankle and foot
0.657 0.343 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.657 0.343 0.000
S95 Injury of blood vessels at ankle and foot level
0.657 0.343 0.000
S94 Injury of nerves at ankle and foot level
0.657 0.343 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.657 0.343 0.000
C53 Malignant neoplasm of cervix uteri
0.656 0.344 0.000
T93 Sequelae of injuries of lower limb
0.656 0.344 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.656 0.344 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.655 0.345 0.000
C51 Malignant neoplasm of vulva
0.655 0.345 0.000
S92.3 Fracture of metatarsal bone
0.655 0.345 0.000
I35.1 Aortic (valve) insufficiency
0.655 0.345 0.000
C77.0 Lymph nodes of head, face and neck
0.654 0.346 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.654 0.346 0.000
G70-G73 Diseases of myoneural junction and muscle
0.653 0.347 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.653 0.347 0.000
H10 Conjunctivitis
0.652 0.348 0.000
G93.8 Other specified disorders of brain
0.652 0.348 0.000
N94.9 Unspecified condition associated with female genital organs and menstrual cycle
0.652 0.348 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.651 0.348 0.000
H21 Other disorders of iris and ciliary body
0.651 0.349 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.651 0.349 0.000
D03.3 Melanoma in situ of other and unspecified parts of face
0.650 0.350 0.000
I67.8 Other specified cerebrovascular diseases
0.650 0.350 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.649 0.350 0.000
Q80-Q89 Other congenital malformations
0.649 0.350 0.000
Q35-Q37 Cleft lip and cleft palate
0.649 0.350 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.649 0.350 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.649 0.350 0.000
C26.0 Intestinal tract, part unspecified
0.649 0.351 0.000
H16.0 Corneal ulcer
0.649 0.351 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.649 0.351 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.649 0.351 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.649 0.351 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.649 0.351 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.649 0.351 0.000
H17 Corneal scars and opacities
0.649 0.351 0.000
H15 Disorders of sclera
0.649 0.351 0.000
S42.9 Fracture of shoulder girdle, part unspecified
0.649 0.351 0.000
S42.8 Fracture of other parts of shoulder and upper arm
0.649 0.351 0.000
S42.7 Multiple fractures of clavicle, scapula and humerus
0.649 0.351 0.000
S42.4 Fracture of lower end of humerus
0.649 0.351 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.648 0.352 0.000
G90 Disorders of autonomic nervous system
0.648 0.352 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.648 0.352 0.000
G92 Toxic encephalopathy
0.648 0.352 0.000
S62 Fracture at wrist and hand level
0.648 0.352 0.000
S86 Injury of muscle and tendon at lower leg level
0.648 0.352 0.000
H35.4 Peripheral retinal degeneration
0.647 0.352 0.000
H36 Retinal disorders in diseases classified elsewhere
0.645 0.355 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.645 0.355 0.000
D04.4 Skin of scalp and neck
0.644 0.356 0.000
S69.9 Unspecified injury of wrist and hand
0.643 0.357 0.000
N94.3 Premenstrual tension syndrome
0.643 0.357 0.000
S70-S79 Injuries to the hip and thigh
0.643 0.357 0.000
G80 Infantile cerebral palsy
0.643 0.357 0.000
I45.9 Conduction disorder, unspecified
0.642 0.358 0.000
F22 Persistent delusional disorders
0.641 0.359 0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.639 0.360 0.000
B06 Rubella [German measles]
0.639 0.360 0.000
B05 Measles
0.639 0.360 0.000
B01 Varicella [chickenpox]
0.639 0.360 0.000
B00 Herpesviral [herpes simplex] infections
0.639 0.360 0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions
0.639 0.360 0.000
B04 Monkeypox
0.639 0.360 0.000
B03 Smallpox
0.639 0.360 0.000
V20-V29 Motorcycle rider injured in transport accident
0.639 0.361 0.000
I09 Other rheumatic heart diseases
0.638 0.362 0.000
I06 Rheumatic aortic valve diseases
0.638 0.362 0.000
B80 Enterobiasis
0.638 0.362 0.000
A48 Other bacterial diseases, not elsewhere classified
0.637 0.363 0.000
C80 Malignant neoplasm without specification of site
0.636 0.363 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.636 0.364 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.636 0.364 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.636 0.364 0.000
F25 Schizoaffective disorders
0.634 0.365 0.000
F23 Acute and transient psychotic disorders
0.634 0.365 0.000
F29 Unspecified nonorganic psychosis
0.634 0.365 0.000
F28 Other nonorganic psychotic disorders
0.634 0.365 0.000
F24 Induced delusional disorder
0.634 0.365 0.000
F21 Schizotypal disorder
0.634 0.365 0.000
I69.3 Sequelae of cerebral infarction
0.634 0.366 0.000
N10-N16 Renal tubulo-interstitial diseases
0.633 0.366 0.000
S91.3 Open wound of other parts of foot
0.633 0.367 0.000
D10-D36 Benign neoplasms
0.633 0.367 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.632 0.367 0.000
C58 Malignant neoplasm of placenta
0.632 0.367 0.000
C52 Malignant neoplasm of vagina
0.632 0.367 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.632 0.368 0.000
W20-W49 Exposure to inanimate mechanical forces
0.632 0.368 0.000
S68 Traumatic amputation of wrist and hand
0.632 0.368 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.631 0.368 0.000
H80-H83 Diseases of inner ear
0.631 0.369 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.631 0.369 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.630 0.370 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.630 0.370 0.000
H70 Mastoiditis and related conditions
0.630 0.370 0.000
H68 Eustachian salpingitis and obstruction
0.630 0.370 0.000
H67 Otitis media in diseases classified elsewhere
0.630 0.370 0.000
H43-H45 Disorders of vitreous body and globe
0.629 0.370 0.000
I42.9 Cardiomyopathy, unspecified
0.629 0.371 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.626 0.374 0.000
I42.6 Alcoholic cardiomyopathy
0.626 0.374 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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