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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs61734876
log Bayes Factor = 12.131
Chromosome 14   position 20,874,411  (GRCh37) Explore rs61734876 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
1.000 0.000 0.000
M20-M25 Other joint disorders
0.999 0.001 0.000
I60-I69 Cerebrovascular diseases
0.998 0.002 0.000
M23 Internal derangement of knee
0.997 0.003 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.996 0.004 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.992 0.008 0.000
M23.3 Other meniscus derangements
0.989 0.011 0.000
Chapter XX External causes of morbidity and mortality
0.985 0.015 0.000
Chapter VI Diseases of the nervous system
0.983 0.017 0.000
I20-I25 Ischaemic heart diseases
0.983 0.017 0.000
M50-M54 Other dorsopathies
0.981 0.019 0.000
D50-D53 Nutritional anaemias
0.974 0.026 0.000
M05-M14 Inflammatory polyarthropathies
0.973 0.027 0.000
M54 Dorsalgia
0.973 0.027 0.000
T43.2 Other and unspecified antidepressants
0.971 0.029 0.000
D51 Vitamin B12 deficiency anaemia
0.967 0.033 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.961 0.039 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.959 0.041 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.954 0.046 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.952 0.048 0.000
M54.5 Low back pain
0.949 0.051 0.000
M15-M19 Arthrosis
0.947 0.053 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.946 0.054 0.000
I30-I52 Other forms of heart disease
0.945 0.055 0.000
M06 Other rheumatoid arthritis
0.943 0.057 0.000
Chapter VIII Diseases of the ear and mastoid process
0.941 0.059 0.000
M80-M85 Disorders of bone density and structure
0.937 0.063 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.936 0.064 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.931 0.069 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.930 0.070 0.000
I25 Chronic ischaemic heart disease
0.928 0.072 0.000
M22 Disorders of patella
0.921 0.079 0.000
I21 Acute myocardial infarction
0.920 0.080 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.916 0.084 0.000
I21.9 Acute myocardial infarction, unspecified
0.913 0.087 0.000
M54.56 Low back pain (Lumbar region)
0.912 0.088 0.000
M17 Gonarthrosis [arthrosis of knee]
0.909 0.091 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.907 0.093 0.000
G35 Multiple sclerosis
0.906 0.094 0.000
I47 Paroxysmal tachycardia
0.903 0.097 0.000
S20-S29 Injuries to the thorax
0.903 0.097 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.902 0.098 0.000
H60-H62 Diseases of external ear
0.901 0.099 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.901 0.099 0.000
I50 Heart failure
0.901 0.099 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.897 0.103 0.000
I60 Subarachnoid haemorrhage
0.894 0.106 0.000
M17.9 Gonarthrosis, unspecified
0.893 0.107 0.000
I05-I09 Chronic rheumatic heart diseases
0.893 0.107 0.000
I26 Pulmonary embolism
0.891 0.109 0.000
G62 Other polyneuropathies
0.890 0.110 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.886 0.114 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.883 0.117 0.000
M23.8 Other internal derangements of knee
0.882 0.118 0.000
M06.9 Rheumatoid arthritis, unspecified
0.880 0.120 0.000
X60-X84 Intentional self-harm
0.874 0.126 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.874 0.126 0.000
M23.4 Loose body in knee
0.871 0.129 0.000
M07 Psoriatic and enteropathic arthropathies
0.871 0.129 0.000
I67 Other cerebrovascular diseases
0.868 0.132 0.000
S80-S89 Injuries to the knee and lower leg
0.867 0.133 0.000
H61 Other disorders of external ear
0.866 0.134 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.863 0.137 0.000
T42.4 Benzodiazepines
0.860 0.140 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.859 0.141 0.000
G62.9 Polyneuropathy, unspecified
0.855 0.145 0.000
S40-S49 Injuries to the shoulder and upper arm
0.854 0.146 0.000
I30 Acute pericarditis
0.854 0.146 0.000
I69 Sequelae of cerebrovascular disease
0.854 0.146 0.000
G20-G26 Extrapyramidal and movement disorders
0.854 0.146 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.853 0.147 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.850 0.150 0.000
H65-H75 Diseases of middle ear and mastoid
0.848 0.152 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.848 0.152 0.000
I62 Other nontraumatic intracranial haemorrhage
0.846 0.154 0.000
M54.1 Radiculopathy
0.833 0.167 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.833 0.167 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.832 0.167 0.000
T51 Toxic effect of alcohol
0.832 0.168 0.000
S90-S99 Injuries to the ankle and foot
0.830 0.170 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.830 0.170 0.000
M06.0 Seronegative rheumatoid arthritis
0.829 0.171 0.000
I47.2 Ventricular tachycardia
0.825 0.175 0.000
M45-M49 Spondylopathies
0.821 0.179 0.000
I67.8 Other specified cerebrovascular diseases
0.820 0.180 0.000
I50.1 Left ventricular failure
0.818 0.182 0.000
H61.2 Impacted cerumen
0.814 0.186 0.000
M54.57 Low back pain (Lumbosacral region)
0.810 0.190 0.000
S81 Open wound of lower leg
0.809 0.191 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.805 0.195 0.000
I22 Subsequent myocardial infarction
0.805 0.195 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.805 0.195 0.000
M54.4 Lumbago with sciatica
0.803 0.196 0.000
M30 Polyarteritis nodosa and related conditions
0.802 0.198 0.000
M85 Other disorders of bone density and structure
0.802 0.198 0.000
M07.3 Other psoriatic arthropathies
0.798 0.202 0.000
M22.4 Chondromalacia patellae
0.796 0.204 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.794 0.206 0.000
I50.0 Congestive heart failure
0.794 0.206 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.793 0.207 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.792 0.208 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.789 0.211 0.000
M84 Disorders of continuity of bone
0.787 0.213 0.000
M54.2 Cervicalgia
0.786 0.214 0.000
T51.0 Ethanol
0.785 0.215 0.000
D60-D64 Aplastic and other anaemias
0.784 0.216 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.783 0.217 0.000
I05 Rheumatic mitral valve diseases
0.782 0.218 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.782 0.218 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.781 0.219 0.000
M23.49 Loose body in knee-Unspec lig/men
0.781 0.219 0.000
V20-V29 Motorcycle rider injured in transport accident
0.779 0.221 0.000
S00-S09 Injuries to the head
0.778 0.222 0.000
M46 Other inflammatory spondylopathies
0.778 0.222 0.000
Q50-Q56 Congenital malformations of genital organs
0.777 0.223 0.000
M60-M63 Disorders of muscles
0.777 0.223 0.000
G25 Other extrapyramidal and movement disorders
0.776 0.224 0.000
M81 Osteoporosis without pathological fracture
0.774 0.226 0.000
T66-T78 Other and unspecified effects of external causes
0.773 0.227 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.772 0.228 0.000
Y48 Anaesthetics and therapeutic gases
0.772 0.228 0.000
T92 Sequelae of injuries of upper limb
0.771 0.229 0.000
M54.50 Low back pain (Multiple sites in spine)
0.770 0.230 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.769 0.231 0.000
G61 Inflammatory polyneuropathy
0.768 0.232 0.000
M54.8 Other dorsalgia
0.766 0.234 0.000
G70-G73 Diseases of myoneural junction and muscle
0.762 0.238 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.762 0.238 0.000
I47.1 Supraventricular tachycardia
0.761 0.239 0.000
I08 Multiple valve diseases
0.761 0.239 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.760 0.240 0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system
0.760 0.240 0.000
H61.0 Perichondritis of external ear
0.760 0.240 0.000
S29 Other and unspecified injuries of thorax
0.758 0.242 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.758 0.242 0.000
M21 Other acquired deformities of limbs
0.758 0.242 0.000
X50-X57 Overexertion, travel and privation
0.756 0.244 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.755 0.245 0.000
S10-S19 Injuries to the neck
0.755 0.245 0.000
Y52 Agents primarily affecting the cardiovascular system
0.754 0.246 0.000
M25 Other joint disorders, not elsewhere classified
0.752 0.248 0.000
M24 Other specific joint derangements
0.752 0.248 0.000
D80-D89 Certain disorders involving the immune mechanism
0.752 0.248 0.000
I25.5 Ischaemic cardiomyopathy
0.751 0.248 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.751 0.249 0.000
M34 Systemic sclerosis
0.751 0.249 0.000
T79-T79 Certain early complications of trauma
0.750 0.250 0.000
Y95 Nosocomial condition
0.750 0.250 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.749 0.251 0.000
M23.9 Internal derangement of knee, unspecified
0.749 0.251 0.000
M22.2 Patellofemoral disorders
0.747 0.253 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.746 0.254 0.000
S40 Superficial injury of shoulder and upper arm
0.746 0.254 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.746 0.254 0.000
V10-V19 Pedal cyclist injured in transport accident
0.745 0.255 0.000
I45 Other conduction disorders
0.745 0.255 0.000
M86-M90 Other osteopathies
0.744 0.256 0.000
I24 Other acute ischaemic heart diseases
0.744 0.256 0.000
M15 Polyarthrosis
0.743 0.257 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.742 0.258 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.742 0.258 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.742 0.258 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.742 0.258 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.737 0.263 0.000
W50-W64 Exposure to animate mechanical forces
0.735 0.264 0.000
I31 Other diseases of pericardium
0.735 0.265 0.000
M22.8 Other disorders of patella
0.734 0.266 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.733 0.267 0.000
M17.1 Other primary gonarthrosis
0.732 0.268 0.000
I30.9 Acute pericarditis, unspecified
0.731 0.269 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.730 0.270 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.730 0.270 0.000
M54.6 Pain in thoracic spine
0.729 0.271 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.729 0.271 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.728 0.272 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.728 0.272 0.000
G90-G99 Other disorders of the nervous system
0.727 0.273 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.726 0.274 0.000
M40-M43 Deforming dorsopathies
0.726 0.274 0.000
I30.1 Infective pericarditis
0.725 0.275 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.725 0.275 0.000
I36 Nonrheumatic tricuspid valve disorders
0.725 0.275 0.000
I69.3 Sequelae of cerebral infarction
0.725 0.275 0.000
I25.2 Old myocardial infarction
0.724 0.276 0.000
S81.9 Open wound of lower leg, part unspecified
0.723 0.277 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.722 0.278 0.000
W20-W49 Exposure to inanimate mechanical forces
0.722 0.278 0.000
V40-V49 Car occupant injured in transport accident
0.721 0.278 0.000
M54.3 Sciatica
0.721 0.279 0.000
Q00-Q07 Congenital malformations of the nervous system
0.719 0.281 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.719 0.281 0.000
M31 Other necrotising vasculopathies
0.719 0.281 0.000
M11 Other crystal arthropathies
0.718 0.282 0.000
I61 Intracerebral haemorrhage
0.717 0.283 0.000
S22.0 Fracture of thoracic vertebra
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.717 0.283 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.717 0.283 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.717 0.283 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.717 0.283 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.717 0.283 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.717 0.283 0.000
T36 Poisoning by systemic antibiotics
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.716 0.284 0.000
M33 Dermatopolymyositis
0.716 0.284 0.000
M32 Systemic lupus erythematosus
0.716 0.284 0.000
H65 Nonsuppurative otitis media
0.716 0.284 0.000
D64 Other anaemias
0.716 0.284 0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.715 0.285 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.715 0.285 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.715 0.285 0.000
M23.1 Discoid meniscus (congenital)
0.715 0.285 0.000
M23.0 Cystic meniscus
0.715 0.285 0.000
I37 Pulmonary valve disorders
0.715 0.285 0.000
M06.4 Inflammatory polyarthropathy
0.714 0.285 0.000
T43.9 Psychotropic drug, unspecified
0.714 0.286 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.714 0.286 0.000
T43.6 Psychostimulants with abuse potential
0.714 0.286 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.714 0.286 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.714 0.286 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.713 0.287 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.712 0.287 0.000
M05 Seropositive rheumatoid arthritis
0.712 0.288 0.000
D55-D59 Haemolytic anaemias
0.711 0.289 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.711 0.289 0.000
X20-X29 Contact with venomous animals and plants
0.710 0.290 0.000
M23.37 Other meniscus derangements-Capsular lig
0.709 0.291 0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.709 0.291 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.706 0.294 0.000
Y35-Y36 Legal intervention and operations of war
0.706 0.294 0.000
Y10-Y34 Event of undetermined intent
0.706 0.294 0.000
Y00-Y09 Assault
0.706 0.294 0.000
X85-X99 Assault
0.706 0.294 0.000
X30-X39 Exposure to forces of nature
0.706 0.294 0.000
X10-X19 Contact with heat and hot substances
0.706 0.294 0.000
X00-X09 Exposure to smoke, fire and flames
0.706 0.294 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.706 0.294 0.000
W75-W84 Other accidental threats to breathing
0.706 0.294 0.000
W65-W74 Accidental drowning and submersion
0.706 0.294 0.000
V98-V99 Other and unspecified transport accidents
0.706 0.294 0.000
V95-V97 Air and space transport accidents
0.706 0.294 0.000
V90-V94 Water transport accidents
0.706 0.294 0.000
V70-V79 Bus occupant injured in transport accident
0.706 0.294 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.706 0.294 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.706 0.294 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.706 0.294 0.000
V01-V09 Pedestrian injured in transport accident
0.706 0.294 0.000
M25.8 Other specified joint disorders
0.706 0.294 0.000
I23 Certain current complications following acute myocardial infarction
0.704 0.295 0.000
M91-M94 Chondropathies
0.704 0.295 0.000
I25.1 Atherosclerotic heart disease
0.704 0.296 0.000
Q28 Other congenital malformations of circulatory system
0.703 0.297 0.000
S01 Open wound of head
0.700 0.300 0.000
S92 Fracture of foot, except ankle
0.699 0.301 0.000
S81.0 Open wound of knee
0.699 0.301 0.000
Y57 Other and unspecified drugs and medicaments
0.699 0.301 0.000
D53 Other nutritional anaemias
0.698 0.302 0.000
M14 Arthropathies in other diseases classified elsewhere
0.698 0.302 0.000
M12 Other specific arthropathies
0.698 0.302 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.698 0.302 0.000
M08 Juvenile arthritis
0.698 0.302 0.000
M54.0 Panniculitis affecting regions of neck and back
0.698 0.302 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.697 0.303 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.696 0.303 0.000
M23.5 Chronic instability of knee
0.695 0.305 0.000
H60 Otitis externa
0.695 0.305 0.000
M06.3 Rheumatoid nodule
0.695 0.305 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.695 0.305 0.000
T39.1 4-Aminophenol derivatives
0.694 0.306 0.000
M82 Osteoporosis in diseases classified elsewhere
0.694 0.306 0.000
H74 Other disorders of middle ear and mastoid
0.694 0.306 0.000
M00-M03 Infectious arthropathies
0.693 0.306 0.000
G30-G32 Other degenerative diseases of the nervous system
0.693 0.307 0.000
D51.8 Other vitamin B12 deficiency anaemias
0.693 0.307 0.000
D51.3 Other dietary vitamin B12 deficiency anaemia
0.693 0.307 0.000
D51.2 Transcobalamin II deficiency
0.693 0.307 0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.693 0.307 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.692 0.308 0.000
T39.0 Salicylates
0.691 0.309 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.688 0.312 0.000
I60.8 Other subarachnoid haemorrhage
0.688 0.312 0.000
T93 Sequelae of injuries of lower limb
0.687 0.313 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.686 0.314 0.000
V80-V89 Other land transport accidents
0.685 0.315 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.684 0.316 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.684 0.316 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.684 0.316 0.000
T42.3 Barbiturates
0.684 0.316 0.000
T42.2 Succinimides and oxazolidinediones
0.684 0.316 0.000
T42.1 Iminostilbenes
0.684 0.316 0.000
T42.0 Hydantoin derivatives
0.684 0.316 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.684 0.316 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.683 0.317 0.000
Q35-Q37 Cleft lip and cleft palate
0.683 0.317 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.683 0.317 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.682 0.317 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.681 0.319 0.000
Q80-Q89 Other congenital malformations
0.681 0.319 0.000
M65-M68 Disorders of synovium and tendon
0.681 0.319 0.000
M54.55 Low back pain (Thoracolumbar region)
0.680 0.320 0.000
M54.54 Low back pain-Thoracic
0.680 0.320 0.000
M54.53 Low back pain-Cervicothoracic
0.680 0.320 0.000
M54.52 Low back pain-Cervical
0.680 0.320 0.000
M54.51 Low back pain-Occipit-atl-axl
0.680 0.320 0.000
M51 Other intervertebral disk disorders
0.680 0.320 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.680 0.320 0.000
M16 Coxarthrosis [arthrosis of hip]
0.680 0.320 0.000
Y48.3 Local anaesthetics
0.679 0.321 0.000
D75 Other diseases of blood and blood-forming organs
0.679 0.321 0.000
X63.0 Home
0.678 0.322 0.000
Y84.8 Other medical procedures
0.678 0.322 0.000
I52 Other heart disorders in diseases classified elsewhere
0.677 0.323 0.000
I48 Atrial fibrillation and flutter
0.677 0.323 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.677 0.323 0.000
I41 Myocarditis in diseases classified elsewhere
0.677 0.323 0.000
I40 Acute myocarditis
0.677 0.323 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.677 0.323 0.000
I32 Pericarditis in diseases classified elsewhere
0.677 0.323 0.000
G25.8 Other specified extrapyramidal and movement disorders
0.677 0.323 0.000
M22.3 Other derangements of patella
0.676 0.323 0.000
S89 Other and unspecified injuries of lower leg
0.676 0.324 0.000
M06.8 Other specified rheumatoid arthritis
0.676 0.324 0.000
M06.2 Rheumatoid bursitis
0.676 0.324 0.000
M06.1 Adult-onset Still's disease
0.676 0.324 0.000
G62.8 Other specified polyneuropathies
0.676 0.324 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.673 0.326 0.000
I35 Nonrheumatic aortic valve disorders
0.673 0.327 0.000
M23.80 Other internal derangements of knee (Multiple sites)
0.673 0.327 0.000
M53 Other dorsopathies, not elsewhere classified
0.672 0.327 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.672 0.328 0.000
M85.8 Other specified disorders of bone density and structure
0.672 0.328 0.000
M83 Adult osteomalacia
0.671 0.328 0.000
G36 Other acute disseminated demyelination
0.671 0.329 0.000
S22.00 Fracture of thoracic vertebra (closed)
0.670 0.330 0.000
I50.9 Heart failure, unspecified
0.669 0.331 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.668 0.332 0.000
M18 Arthrosis of first carpometacarpal joint
0.668 0.332 0.000
G60 Hereditary and idiopathic neuropathy
0.667 0.332 0.000
G64 Other disorders of peripheral nervous system
0.667 0.332 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.667 0.333 0.000
D64.9 Anaemia, unspecified
0.667 0.333 0.000
I28 Other diseases of pulmonary vessels
0.667 0.333 0.000
I25.6 Silent myocardial ischaemia
0.666 0.334 0.000
I25.4 Coronary artery aneurysm
0.666 0.334 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.666 0.334 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.665 0.335 0.000
D52 Folate deficiency anaemia
0.665 0.335 0.000
T92.2 Sequelae of fracture at wrist and hand level
0.663 0.337 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.663 0.337 0.000
S27 Injury of other and unspecified intrathoracic organs
0.663 0.337 0.000
H73 Other disorders of tympanic membrane
0.662 0.338 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.662 0.338 0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.662 0.338 0.000
M54.17 Radiculopathy (Lumbosacral region)
0.662 0.338 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.661 0.338 0.000
Q43 Other congenital malformations of intestine
0.661 0.339 0.000
M22.1 Recurrent subluxation of patella
0.660 0.340 0.000
M22.9 Disorder of patella, unspecified
0.660 0.340 0.000
M22.0 Recurrent dislocation of patella
0.660 0.340 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.660 0.340 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.660 0.340 0.000
I42 Cardiomyopathy
0.660 0.340 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.659 0.340 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.659 0.341 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.659 0.341 0.000
Chapter XXII Codes for special purposes
0.659 0.341 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.656 0.344 0.000
I63 Cerebral infarction
0.656 0.344 0.000
M54.16 Radiculopathy (Lumbar region)
0.656 0.344 0.000
S29.9 Unspecified injury of thorax
0.655 0.345 0.000
M81.9 Osteoporosis, unspecified
0.655 0.345 0.000
I67.2 Cerebral atherosclerosis
0.654 0.346 0.000
M80 Osteoporosis with pathological fracture
0.654 0.346 0.000
I05.2 Mitral stenosis with insufficiency
0.652 0.348 0.000
M17.5 Other secondary gonarthrosis
0.652 0.348 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.652 0.348 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.652 0.348 0.000
G61.0 Guillain-Barre syndrome
0.652 0.348 0.000
I05.0 Mitral stenosis
0.652 0.348 0.000
Q21 Congenital malformations of cardiac septa
0.649 0.351 0.000
S50-S59 Injuries to the elbow and forearm
0.648 0.352 0.000
D73 Diseases of spleen
0.648 0.352 0.000
I47.0 Reentry ventricular arrhythmia
0.648 0.352 0.000
G37 Other demyelinating diseases of central nervous system
0.647 0.352 0.000
Q39 Congenital malformations of oesophagus
0.647 0.353 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.647 0.353 0.000
S26 Injury of heart
0.647 0.353 0.000
S25 Injury of blood vessels of thorax
0.647 0.353 0.000
S24 Injury of nerves and spinal cord at thorax level
0.647 0.353 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.647 0.353 0.000
S21 Open wound of thorax
0.647 0.353 0.000
I45.5 Other specified heart block
0.647 0.353 0.000
T65 Toxic effect of other and unspecified substances
0.647 0.353 0.000
T62 Toxic effect of other noxious substances eaten as food
0.647 0.353 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.647 0.353 0.000
T60 Toxic effect of pesticides
0.647 0.353 0.000
T59 Toxic effect of other gases, fumes and vapours
0.647 0.353 0.000
T57 Toxic effect of other inorganic substances
0.647 0.353 0.000
T56 Toxic effect of metals
0.647 0.353 0.000
T54 Toxic effect of corrosive substances
0.647 0.353 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.647 0.353 0.000
T52 Toxic effect of organic solvents
0.647 0.353 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.647 0.353 0.000
T58 Toxic effect of carbon monoxide
0.647 0.353 0.000
T55 Toxic effect of soaps and detergents
0.647 0.353 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.646 0.354 0.000
I33 Acute and subacute endocarditis
0.646 0.354 0.000
H62 Disorders of external ear in diseases classified elsewhere
0.646 0.354 0.000
Y59 Other and unspecified vaccines and biological substances
0.646 0.354 0.000
Y58 Bacterial vaccines
0.646 0.354 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.646 0.354 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.646 0.354 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.646 0.354 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.646 0.354 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.646 0.354 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.646 0.354 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.646 0.354 0.000
H69 Other disorders of Eustachian tube
0.645 0.355 0.000
T63 Toxic effect of contact with venomous animals
0.645 0.355 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.644 0.356 0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)
0.643 0.357 0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.641 0.359 0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.641 0.359 0.000
I60.5 Subarachnoid haemorrhage from vertebral artery
0.641 0.359 0.000
I60.4 Subarachnoid haemorrhage from basilar artery
0.641 0.359 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.641 0.359 0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.641 0.359 0.000
I09 Other rheumatic heart diseases
0.640 0.360 0.000
I06 Rheumatic aortic valve diseases
0.640 0.360 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.639 0.361 0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.639 0.361 0.000
I25.3 Aneurysm of heart
0.639 0.361 0.000
M85.6 Other cyst of bone
0.638 0.362 0.000
G62.2 Polyneuropathy due to other toxic agents
0.638 0.362 0.000
G62.1 Alcoholic polyneuropathy
0.638 0.362 0.000
G62.0 Drug-induced polyneuropathy
0.638 0.362 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.638 0.362 0.000
X78 Intentional self-harm by sharp object
0.638 0.362 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.637 0.363 0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)
0.637 0.363 0.000
D68 Other coagulation defects
0.637 0.363 0.000
M84.0 Malunion of fracture
0.637 0.363 0.000
T98 Sequelae of other and unspecified effects of external causes
0.637 0.363 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.636 0.363 0.000
I21.4 Acute subendocardial myocardial infarction
0.636 0.364 0.000
Y84.1 Kidney dialysis
0.636 0.364 0.000
M25.87 Other specified joint disorders (Ankle and foot)
0.636 0.364 0.000
T50.8 Diagnostic agents
0.635 0.364 0.000
T50.7 Analeptics and opioid receptor antagonists
0.635 0.364 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.635 0.364 0.000
T50.5 Appetite depressants
0.635 0.364 0.000
T50.4 Drugs affecting uric acid metabolism
0.635 0.364 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.635 0.364 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.635 0.364 0.000
T50.1 Loop [high-ceiling] diuretics
0.635 0.364 0.000
T50.0 Mineralocorticoids and their antagonists
0.635 0.364 0.000
M54.19 Radiculopathy (Site unspecified)
0.634 0.365 0.000
S01.8 Open wound of other parts of head
0.634 0.366 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.634 0.366 0.000
T95 Sequelae of burns, corrosions and frostbite
0.633 0.367 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.633 0.367 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.633 0.367 0.000
H70 Mastoiditis and related conditions
0.633 0.367 0.000
M23.87 Other internal derangements of knee (Capsular ligament)
0.633 0.367 0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)
0.633 0.367 0.000
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)
0.633 0.367 0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.633 0.367 0.000
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.633 0.367 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.631 0.369 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.631 0.369 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.630 0.370 0.000
H61.3 Acquired stenosis of external ear canal
0.630 0.370 0.000
D66 Hereditary factor VIII deficiency
0.630 0.370 0.000
S86 Injury of muscle and tendon at lower leg level
0.629 0.371 0.000
T91 Sequelae of injuries of neck and trunk
0.629 0.371 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.627 0.373 0.000
X84 Intentional self-harm by unspecified means
0.627 0.373 0.000
X83 Intentional self-harm by other specified means
0.627 0.373 0.000
X82 Intentional self-harm by crashing of motor vehicle
0.627 0.373 0.000
X81 Intentional self-harm by jumping or lying before moving object
0.627 0.373 0.000
X80 Intentional self-harm by jumping from a high place
0.627 0.373 0.000
X79 Intentional self-harm by blunt object
0.627 0.373 0.000
X77 Intentional self-harm by steam, hot vapours and hot objects
0.627 0.373 0.000
X76 Intentional self-harm by smoke, fire and flames
0.627 0.373 0.000
X75 Intentional self-harm by explosive material
0.627 0.373 0.000
X74 Intentional self-harm by other and unspecified firearm discharge
0.627 0.373 0.000
X73 Intentional self-harm by rifle, shotgun and larger firearm discharge
0.627 0.373 0.000
X72 Intentional self-harm by handgun discharge
0.627 0.373 0.000
X71 Intentional self-harm by drowning and submersion
0.627 0.373 0.000
X70 Intentional self-harm by hanging, strangulation and suffocation
0.627 0.373 0.000
X69 Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
0.627 0.373 0.000
X68 Intentional self-poisoning by and exposure to pesticides
0.627 0.373 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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