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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs11088859
log Bayes Factor = 14.6883
Chromosome 21   position 22,689,344  (GRCh37) Explore rs11088859 on Ensembl!
Variant rs11088859 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
0.999 0.001 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.999 0.001 0.000
Chapter XI Diseases of the digestive system
0.999 0.001 0.000
K80.1 Calculus of gallbladder with other cholecystitis
0.998 0.002 0.000
K80 Cholelithiasis
0.998 0.002 0.000
Chapter VI Diseases of the nervous system
0.996 0.004 0.000
Chapter II Neoplasms
0.996 0.004 0.000
Chapter I Certain infectious and parasitic diseases
0.996 0.004 0.000
Chapter IX Diseases of the circulatory system
0.994 0.006 0.000
Chapter XIV Diseases of the genitourinary system
0.993 0.007 0.000
A00-A09 Intestinal infectious diseases
0.992 0.008 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.989 0.011 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.986 0.014 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.984 0.016 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.978 0.022 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.978 0.022 0.000
N20-N23 Urolithiasis
0.971 0.029 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.965 0.035 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.964 0.036 0.000
I30-I52 Other forms of heart disease
0.963 0.037 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.962 0.038 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.961 0.039 0.000
C15-C26 Malignant neoplasms of digestive organs
0.945 0.055 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.943 0.057 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.941 0.059 0.000
I77 Other disorders of arteries and arterioles
0.937 0.063 0.000
I74 Arterial embolism and thrombosis
0.934 0.066 0.000
N20 Calculus of kidney and ureter
0.933 0.067 0.000
K83 Other diseases of biliary tract
0.925 0.075 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.923 0.077 0.000
N17-N19 Renal failure
0.914 0.086 0.000
I49 Other cardiac arrhythmias
0.913 0.087 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.911 0.089 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.910 0.090 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.910 0.090 0.000
Z92 Personal history of medical treatment
0.904 0.096 0.000
G40-G47 Episodic and paroxysmal disorders
0.903 0.097 0.000
Z45 Adjustment and management of implanted device
0.902 0.098 0.000
N60-N64 Disorders of breast
0.896 0.104 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.894 0.106 0.000
I77.1 Stricture of artery
0.893 0.107 0.000
D00-D09 In situ neoplasms
0.892 0.108 0.000
I05-I09 Chronic rheumatic heart diseases
0.892 0.108 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.891 0.109 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.888 0.112 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.888 0.112 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.887 0.113 0.000
M20-M25 Other joint disorders
0.886 0.114 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.885 0.115 0.000
Chapter X Diseases of the respiratory system
0.885 0.115 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.885 0.115 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.883 0.117 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.882 0.118 0.000
S60-S69 Injuries to the wrist and hand
0.876 0.124 0.000
Z42 Follow-up care involving plastic surgery
0.875 0.125 0.000
N20.1 Calculus of ureter
0.874 0.126 0.000
Chapter VIII Diseases of the ear and mastoid process
0.872 0.128 0.000
G56 Mononeuropathies of upper limb
0.866 0.134 0.000
Z02 Examination and encounter for administrative purposes
0.862 0.138 0.000
M70-M79 Other soft tissue disorders
0.862 0.138 0.000
N23 Unspecified renal colic
0.859 0.141 0.000
I49.9 Cardiac arrhythmia, unspecified
0.859 0.141 0.000
A08 Viral and other specified intestinal infections
0.857 0.143 0.000
C18 Malignant neoplasm of colon
0.852 0.148 0.000
Z93 Artificial opening status
0.851 0.149 0.000
E70-E90 Metabolic disorders
0.849 0.151 0.000
N19 Unspecified renal failure
0.849 0.151 0.000
K05 Gingivitis and periodontal diseases
0.848 0.151 0.000
M35 Other systemic involvement of connective tissue
0.845 0.155 0.000
C44 Other malignant neoplasms of skin
0.844 0.156 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.844 0.156 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.841 0.159 0.000
K50-K52 Noninfective enteritis and colitis
0.838 0.162 0.000
E87.6 Hypokalaemia
0.838 0.162 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.837 0.163 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.837 0.163 0.000
B95-B98 Bacterial, viral and other infectious agents
0.836 0.164 0.000
Chapter XXII Codes for special purposes
0.834 0.165 0.000
Z45.2 Adjustment and management of vascular access device
0.834 0.166 0.000
N10-N16 Renal tubulo-interstitial diseases
0.834 0.166 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.831 0.169 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.824 0.176 0.000
K86 Other diseases of pancreas
0.824 0.176 0.000
M72 Fibroblastic disorders
0.823 0.177 0.000
C44.5 Skin of trunk
0.822 0.178 0.000
I70 Atherosclerosis
0.822 0.178 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.821 0.179 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.821 0.179 0.000
K82 Other diseases of gallbladder
0.820 0.180 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.819 0.181 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.819 0.181 0.000
G56.0 Carpal tunnel syndrome
0.819 0.181 0.000
I78 Diseases of capillaries
0.818 0.182 0.000
G62 Other polyneuropathies
0.818 0.182 0.000
M35.3 Polymyalgia rheumatica
0.817 0.183 0.000
G20-G26 Extrapyramidal and movement disorders
0.815 0.185 0.000
I51 Complications and ill-defined descriptions of heart disease
0.814 0.186 0.000
K14 Diseases of tongue
0.814 0.186 0.000
Z86 Personal history of certain other diseases
0.813 0.187 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.813 0.187 0.000
K04 Diseases of pulp and periapical tissues
0.809 0.191 0.000
R14 Flatulence and related conditions
0.807 0.193 0.000
I46 Cardiac arrest
0.806 0.194 0.000
K08 Other disorders of teeth and supporting structures
0.806 0.194 0.000
N62 Hypertrophy of breast
0.802 0.198 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.802 0.198 0.000
Z01.6 Radiological examination, not elsewhere classified
0.801 0.199 0.000
K85 Acute pancreatitis
0.797 0.202 0.000
G47 Sleep disorders
0.797 0.203 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.797 0.203 0.000
K10 Other diseases of jaws
0.795 0.205 0.000
G90-G99 Other disorders of the nervous system
0.794 0.206 0.000
K80.4 Calculus of bile duct with cholecystitis
0.794 0.206 0.000
Z46 Fitting and adjustment of other devices
0.793 0.207 0.000
I71 Aortic aneurysm and dissection
0.792 0.208 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.791 0.209 0.000
H90-H95 Other disorders of ear
0.790 0.210 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.786 0.214 0.000
Z42.1 Follow-up care involving plastic surgery of breast
0.785 0.215 0.000
Z97 Presence of other devices
0.783 0.217 0.000
C20 Malignant neoplasm of rectum
0.782 0.218 0.000
A04 Other bacterial intestinal infections
0.782 0.218 0.000
Z40 Prophylactic surgery
0.782 0.218 0.000
S80-S89 Injuries to the knee and lower leg
0.779 0.221 0.000
T66-T78 Other and unspecified effects of external causes
0.778 0.222 0.000
K83.1 Obstruction of bile duct
0.778 0.222 0.000
Z02.8 Other examinations for administrative purposes
0.774 0.226 0.000
R42 Dizziness and giddiness
0.774 0.226 0.000
M05-M14 Inflammatory polyarthropathies
0.773 0.227 0.000
L60-L75 Disorders of skin appendages
0.773 0.227 0.000
K83.0 Cholangitis
0.772 0.228 0.000
Z03.1 Observation for suspected malignant neoplasm
0.771 0.229 0.000
C18.7 Sigmoid colon
0.771 0.229 0.000
N20.2 Calculus of kidney with calculus of ureter
0.769 0.230 0.000
I34 Nonrheumatic mitral valve disorders
0.769 0.231 0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.768 0.232 0.000
I72 Other aneurysm
0.768 0.232 0.000
I50 Heart failure
0.768 0.232 0.000
Z41 Procedures for purposes other than remedying health state
0.766 0.234 0.000
A30-A49 Other bacterial diseases
0.766 0.234 0.000
S20-S29 Injuries to the thorax
0.766 0.234 0.000
Z43 Attention to artificial openings
0.765 0.235 0.000
C44.7 Skin of lower limb, including hip
0.765 0.235 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.764 0.236 0.000
J40-J47 Chronic lower respiratory diseases
0.764 0.236 0.000
K83.8 Other specified diseases of biliary tract
0.762 0.238 0.000
C78.0 Secondary malignant neoplasm of lung
0.762 0.238 0.000
K70-K77 Diseases of liver
0.761 0.239 0.000
R26 Abnormalities of gait and mobility
0.761 0.239 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.760 0.240 0.000
Z93.2 Ileostomy status
0.759 0.241 0.000
N72 Inflammatory disease of cervix uteri
0.758 0.242 0.000
I33 Acute and subacute endocarditis
0.757 0.242 0.000
S62 Fracture at wrist and hand level
0.757 0.242 0.000
E20-E35 Disorders of other endocrine glands
0.757 0.243 0.000
R12 Heartburn
0.755 0.245 0.000
Z03.9 Observation for suspected disease or condition, unspecified
0.754 0.246 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.754 0.246 0.000
N63 Unspecified lump in breast
0.753 0.247 0.000
Z80 Family history of malignant neoplasm
0.753 0.247 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.752 0.248 0.000
M30 Polyarteritis nodosa and related conditions
0.751 0.249 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.751 0.249 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.751 0.249 0.000
E87.5 Hyperkalaemia
0.749 0.251 0.000
I05 Rheumatic mitral valve diseases
0.748 0.252 0.000
B35-B49 Mycoses
0.745 0.255 0.000
G25 Other extrapyramidal and movement disorders
0.745 0.255 0.000
K05.6 Periodontal disease, unspecified
0.743 0.256 0.000
L40-L45 Papulosquamous disorders
0.742 0.258 0.000
N25-N29 Other disorders of kidney and ureter
0.742 0.258 0.000
I08 Multiple valve diseases
0.741 0.259 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.741 0.259 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.740 0.260 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.740 0.260 0.000
Z90.0 Acquired absence of part of head and neck
0.740 0.260 0.000
Z49 Care involving dialysis
0.740 0.260 0.000
K51 Ulcerative colitis
0.740 0.260 0.000
J95-J99 Other diseases of the respiratory system
0.739 0.261 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.739 0.261 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.738 0.262 0.000
N99-N99 Other disorders of the genitourinary system
0.737 0.263 0.000
N20.0 Calculus of kidney
0.735 0.265 0.000
N60 Benign mammary dysplasia
0.734 0.266 0.000
D68 Other coagulation defects
0.733 0.267 0.000
C78.2 Secondary malignant neoplasm of pleura
0.733 0.267 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.731 0.269 0.000
Z90.5 Acquired absence of kidney
0.730 0.270 0.000
A08.4 Viral intestinal infection, unspecified
0.730 0.270 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.729 0.271 0.000
C16 Malignant neoplasm of stomach
0.728 0.272 0.000
Z94 Transplanted organ and tissue status
0.727 0.273 0.000
I49.4 Other and unspecified premature depolarisation
0.727 0.273 0.000
Z86.1 Personal history of infectious and parasitic diseases
0.727 0.273 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.727 0.273 0.000
G62.8 Other specified polyneuropathies
0.727 0.273 0.000
I74.5 Embolism and thrombosis of iliac artery
0.726 0.274 0.000
Z42.2 Follow-up care involving plastic surgery of other parts of trunk
0.723 0.277 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.723 0.277 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.723 0.277 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.722 0.278 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.721 0.279 0.000
Z86.7 Personal history of diseases of the circulatory system
0.719 0.281 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.719 0.281 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.718 0.282 0.000
L50-L54 Urticaria and erythema
0.718 0.282 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.718 0.282 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
G30-G32 Other degenerative diseases of the nervous system
0.717 0.283 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.716 0.284 0.000
K80.3 Calculus of bile duct with cholangitis
0.716 0.284 0.000
K80.8 Other cholelithiasis
0.716 0.284 0.000
S61 Open wound of wrist and hand
0.715 0.285 0.000
D46 Myelodysplastic syndromes
0.714 0.286 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.714 0.286 0.000
G58 Other mononeuropathies
0.714 0.286 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.714 0.286 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.714 0.286 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.714 0.286 0.000
B99-B99 Other infectious diseases
0.714 0.286 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.714 0.286 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.714 0.286 0.000
B65-B83 Helminthiases
0.714 0.286 0.000
B50-B64 Protozoal diseases
0.714 0.286 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.714 0.286 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.714 0.286 0.000
A80-A89 Viral infections of the central nervous system
0.714 0.286 0.000
A75-A79 Rickettsioses
0.714 0.286 0.000
A70-A74 Other diseases caused by chlamydiae
0.714 0.286 0.000
A65-A69 Other spirochaetal diseases
0.714 0.286 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.714 0.286 0.000
A20-A28 Certain zoonotic bacterial diseases
0.714 0.286 0.000
A15-A19 Tuberculosis
0.714 0.286 0.000
I77.6 Arteritis, unspecified
0.714 0.286 0.000
Z52 Donors of organs and tissues
0.714 0.286 0.000
G70-G73 Diseases of myoneural junction and muscle
0.713 0.287 0.000
S00-S09 Injuries to the head
0.713 0.287 0.000
N18 Chronic renal failure
0.713 0.287 0.000
I00-I02 Acute rheumatic fever
0.713 0.287 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.712 0.288 0.000
Chapter XX External causes of morbidity and mortality
0.712 0.288 0.000
Z89 Acquired absence of limb
0.712 0.288 0.000
H91 Other hearing loss
0.712 0.288 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.712 0.288 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.711 0.289 0.000
A07 Other protozoal intestinal diseases
0.711 0.289 0.000
A06 Amoebiasis
0.711 0.289 0.000
A05 Other bacterial foodborne intoxications
0.711 0.289 0.000
A03 Shigellosis
0.711 0.289 0.000
A02 Other Salmonella infections
0.711 0.289 0.000
A01 Typhoid and paratyphoid fevers
0.711 0.289 0.000
A00 Cholera
0.711 0.289 0.000
I49.1 Atrial premature depolarisation
0.710 0.290 0.000
M80-M85 Disorders of bone density and structure
0.710 0.290 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.709 0.291 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.709 0.291 0.000
S70-S79 Injuries to the hip and thigh
0.709 0.291 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.708 0.292 0.000
Z04 Examination and observation for other reasons
0.708 0.292 0.000
Z11.0 Special screening examination for intestinal infectious diseases
0.708 0.292 0.000
M50-M54 Other dorsopathies
0.708 0.292 0.000
Z50 Care involving use of rehabilitation procedures
0.707 0.293 0.000
Z10 Routine general health check-up of defined subpopulation
0.707 0.293 0.000
M86-M90 Other osteopathies
0.706 0.294 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.706 0.294 0.000
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin
0.705 0.295 0.000
D09 Carcinoma in situ of other and unspecified sites
0.705 0.295 0.000
I51.7 Cardiomegaly
0.705 0.295 0.000
C15 Malignant neoplasm of oesophagus
0.703 0.296 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.702 0.298 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.702 0.298 0.000
Z54 Convalescence
0.701 0.298 0.000
Z44 Fitting and adjustment of external prosthetic device
0.701 0.298 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.701 0.299 0.000
E86 Volume depletion
0.701 0.299 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.701 0.299 0.000
I49.8 Other specified cardiac arrhythmias
0.700 0.300 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.699 0.301 0.000
C60-C63 Malignant neoplasms of male genital organs
0.698 0.302 0.000
B15-B19 Viral hepatitis
0.698 0.302 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.698 0.302 0.000
Z03.4 Observation for suspected myocardial infarction
0.698 0.302 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.698 0.302 0.000
I38 Endocarditis, valve unspecified
0.697 0.303 0.000
C50-C50 Malignant neoplasm of breast
0.697 0.303 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.696 0.304 0.000
I78.1 Naevus, nonneoplastic
0.695 0.305 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.695 0.305 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.694 0.306 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.693 0.307 0.000
T33-T35 Frostbite
0.692 0.308 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.692 0.308 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.692 0.308 0.000
T00-T07 Injuries involving multiple body regions
0.692 0.308 0.000
S10-S19 Injuries to the neck
0.692 0.308 0.000
Z86.4 Personal history of psychoactive substance abuse
0.692 0.308 0.000
M91-M94 Chondropathies
0.691 0.309 0.000
M60-M63 Disorders of muscles
0.691 0.309 0.000
M00-M03 Infectious arthropathies
0.691 0.309 0.000
I52 Other heart disorders in diseases classified elsewhere
0.691 0.309 0.000
I48 Atrial fibrillation and flutter
0.691 0.309 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.691 0.309 0.000
I41 Myocarditis in diseases classified elsewhere
0.691 0.309 0.000
I40 Acute myocarditis
0.691 0.309 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.691 0.309 0.000
I37 Pulmonary valve disorders
0.691 0.309 0.000
I36 Nonrheumatic tricuspid valve disorders
0.691 0.309 0.000
I32 Pericarditis in diseases classified elsewhere
0.691 0.309 0.000
I30 Acute pericarditis
0.691 0.309 0.000
D45 Polycythaemia vera
0.690 0.310 0.000
Z03.6 Observation for suspected toxic effect from ingested substance
0.689 0.310 0.000
Z03.2 Observation for suspected mental and behavioural disorders
0.689 0.310 0.000
Z03.0 Observation for suspected tuberculosis
0.689 0.310 0.000
K09 Cysts of oral region, not elsewhere classified
0.689 0.311 0.000
K03 Other diseases of hard tissues of teeth
0.689 0.311 0.000
K00 Disorders of tooth development and eruption
0.689 0.311 0.000
J30-J39 Other diseases of upper respiratory tract
0.689 0.311 0.000
E65-E68 Obesity and other hyperalimentation
0.689 0.311 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.688 0.312 0.000
K07 Dentofacial anomalies [including malocclusion]
0.688 0.312 0.000
Q60-Q64 Congenital malformations of the urinary system
0.688 0.312 0.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.688 0.312 0.000
I35 Nonrheumatic aortic valve disorders
0.687 0.313 0.000
N21 Calculus of lower urinary tract
0.687 0.313 0.000
Z48 Other surgical follow-up care
0.687 0.313 0.000
G43 Migraine
0.687 0.313 0.000
D06 Carcinoma in situ of cervix uteri
0.686 0.313 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.686 0.314 0.000
R27 Other lack of coordination
0.686 0.314 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.686 0.314 0.000
S90-S99 Injuries to the ankle and foot
0.686 0.314 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.684 0.316 0.000
Z01.5 Diagnostic skin and sensitisation tests
0.684 0.316 0.000
M65-M68 Disorders of synovium and tendon
0.684 0.316 0.000
C25 Malignant neoplasm of pancreas
0.683 0.317 0.000
T92 Sequelae of injuries of upper limb
0.683 0.317 0.000
G25.8 Other specified extrapyramidal and movement disorders
0.682 0.318 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.682 0.318 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.681 0.319 0.000
G47.3 Sleep apnoea
0.681 0.319 0.000
M22 Disorders of patella
0.681 0.319 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.681 0.319 0.000
Z80.3 Family history of malignant neoplasm of breast
0.680 0.320 0.000
L60 Nail disorders
0.680 0.320 0.000
I49.5 Sick sinus syndrome
0.680 0.320 0.000
K08.1 Loss of teeth due to accident, extraction or local periodontal disease
0.680 0.320 0.000
S80 Superficial injury of lower leg
0.680 0.320 0.000
M31 Other necrotising vasculopathies
0.680 0.320 0.000
M15-M19 Arthrosis
0.680 0.320 0.000
T79-T79 Certain early complications of trauma
0.679 0.321 0.000
I50.1 Left ventricular failure
0.679 0.321 0.000
K82.4 Cholesterolosis of gallbladder
0.679 0.321 0.000
I47 Paroxysmal tachycardia
0.679 0.321 0.000
C79 Secondary malignant neoplasm of other sites
0.678 0.322 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.677 0.323 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.677 0.323 0.000
C21 Malignant neoplasm of anus and anal canal
0.677 0.323 0.000
C17 Malignant neoplasm of small intestine
0.677 0.323 0.000
C23 Malignant neoplasm of gallbladder
0.677 0.323 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.677 0.323 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.677 0.323 0.000
R17 Unspecified jaundice
0.676 0.324 0.000
Z84 Family history of other conditions
0.676 0.324 0.000
Z81 Family history of mental and behavioural disorders
0.676 0.324 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.676 0.324 0.000
I07 Rheumatic tricuspid valve diseases
0.676 0.324 0.000
N13 Obstructive and reflux uropathy
0.675 0.324 0.000
K10.8 Other specified diseases of jaws
0.675 0.325 0.000
K35-K38 Diseases of appendix
0.674 0.326 0.000
A08.1 Acute gastro-enteropathy due to Norwalk agent
0.673 0.327 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.672 0.328 0.000
I77.8 Other specified disorders of arteries and arterioles
0.672 0.328 0.000
I77.5 Necrosis of artery
0.672 0.328 0.000
I77.4 Coeliac artery compression syndrome
0.672 0.328 0.000
I77.3 Arterial fibromuscular dysplasia
0.672 0.328 0.000
I77.2 Rupture of artery
0.672 0.328 0.000
I77.0 Arteriovenous fistula, acquired
0.672 0.328 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.672 0.328 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.670 0.330 0.000
I74.8 Embolism and thrombosis of other arteries
0.670 0.330 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.670 0.330 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.670 0.330 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.670 0.330 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.670 0.330 0.000
Chapter VII Diseases of the eye and adnexa
0.670 0.330 0.000
K04.8 Radicular cyst
0.670 0.330 0.000
N20.9 Urinary calculus, unspecified
0.669 0.331 0.000
K14.0 Glossitis
0.669 0.331 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.668 0.332 0.000
Z93.0 Tracheostomy status
0.668 0.332 0.000
S50-S59 Injuries to the elbow and forearm
0.667 0.333 0.000
I46.9 Cardiac arrest, unspecified
0.665 0.335 0.000
S69 Other and unspecified injuries of wrist and hand
0.665 0.335 0.000
D07.5 Prostate
0.665 0.335 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.664 0.336 0.000
K05.3 Chronic periodontitis
0.663 0.337 0.000
K83.9 Disease of biliary tract, unspecified
0.663 0.337 0.000
K83.5 Biliary cyst
0.663 0.337 0.000
K83.4 Spasm of sphincter of Oddi
0.663 0.337 0.000
K83.3 Fistula of bile duct
0.663 0.337 0.000
K83.2 Perforation of bile duct
0.663 0.337 0.000
S40-S49 Injuries to the shoulder and upper arm
0.663 0.337 0.000
I31 Other diseases of pericardium
0.662 0.338 0.000
G54 Nerve root and plexus disorders
0.662 0.338 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.662 0.338 0.000
G52 Disorders of other cranial nerves
0.662 0.338 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.662 0.338 0.000
D68.8 Other specified coagulation defects
0.662 0.338 0.000
H60-H62 Diseases of external ear
0.662 0.338 0.000
Z45.8 Adjustment and management of other implanted devices
0.661 0.338 0.000
C44.1 Skin of eyelid, including canthus
0.661 0.339 0.000
S67 Crushing injury of wrist and hand
0.661 0.339 0.000
Z46.6 Fitting and adjustment of urinary device
0.660 0.340 0.000
K12 Stomatitis and related lesions
0.659 0.341 0.000
M24 Other specific joint derangements
0.659 0.341 0.000
I42 Cardiomyopathy
0.659 0.341 0.000
Z45.1 Adjustment and management of infusion pump
0.658 0.342 0.000
S64 Injury of nerves at wrist and hand level
0.657 0.343 0.000
C18.6 Descending colon
0.656 0.344 0.000
H91.9 Hearing loss, unspecified
0.656 0.344 0.000
K04.5 Chronic apical periodontitis
0.655 0.345 0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.655 0.345 0.000
I49.2 Junctional premature depolarisation
0.654 0.346 0.000
I49.0 Ventricular fibrillation and flutter
0.654 0.346 0.000
K11 Diseases of salivary glands
0.654 0.346 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.653 0.347 0.000
J60-J70 Lung diseases due to external agents
0.653 0.347 0.000
M45-M49 Spondylopathies
0.653 0.347 0.000
D05 Carcinoma in situ of breast
0.653 0.347 0.000
G61 Inflammatory polyneuropathy
0.653 0.347 0.000
G60 Hereditary and idiopathic neuropathy
0.653 0.347 0.000
G64 Other disorders of peripheral nervous system
0.653 0.347 0.000
K13 Other diseases of lip and oral mucosa
0.653 0.347 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.653 0.347 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.653 0.347 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.653 0.347 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.653 0.347 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.653 0.347 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.651 0.348 0.000
C18.2 Ascending colon
0.651 0.349 0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.651 0.349 0.000
G56.2 Lesion of ulnar nerve
0.651 0.349 0.000
J20-J22 Other acute lower respiratory infections
0.651 0.349 0.000
Z92.0 Personal history of contraception
0.650 0.349 0.000
K51.9 Ulcerative colitis, unspecified
0.650 0.350 0.000
M71 Other bursopathies
0.650 0.350 0.000
L40 Psoriasis
0.650 0.350 0.000
C51-C58 Malignant neoplasms of female genital organs
0.650 0.350 0.000
Z90.3 Acquired absence of part of stomach
0.649 0.351 0.000
H80-H83 Diseases of inner ear
0.649 0.351 0.000
G62.9 Polyneuropathy, unspecified
0.648 0.351 0.000
K80.2 Calculus of gallbladder without cholecystitis
0.648 0.352 0.000
Z92.9 Personal history of medical treatment, unspecified
0.648 0.352 0.000
Z92.8 Personal history of other medical treatment
0.648 0.352 0.000
Z92.5 Personal history of rehabilitation measures
0.648 0.352 0.000
Z93.5 Cystostomy status
0.648 0.352 0.000
M25 Other joint disorders, not elsewhere classified
0.648 0.352 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.647 0.353 0.000
G41 Status epilepticus
0.647 0.353 0.000
Z45.9 Adjustment and management of unspecified implanted device
0.647 0.353 0.000
Z45.3 Adjustment and management of implanted hearing device
0.647 0.353 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.646 0.353 0.000
Z92.3 Personal history of irradiation
0.646 0.354 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.646 0.354 0.000
N10 Acute tubulo-interstitial nephritis
0.645 0.355 0.000
N71 Inflammatory disease of uterus, except cervix
0.645 0.355 0.000
K08.8 Other specified disorders of teeth and supporting structures
0.645 0.355 0.000
T78 Adverse effects, not elsewhere classified
0.644 0.355 0.000
D80-D89 Certain disorders involving the immune mechanism
0.644 0.356 0.000
K86.1 Other chronic pancreatitis
0.644 0.356 0.000
D04 Carcinoma in situ of skin
0.644 0.356 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.643 0.357 0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
0.643 0.357 0.000
C44.6 Skin of upper limb, including shoulder
0.643 0.357 0.000
I34.0 Mitral (valve) insufficiency
0.643 0.357 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.642 0.358 0.000
Z43.3 Attention to colostomy
0.641 0.359 0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms
0.641 0.359 0.000
N00-N08 Glomerular diseases
0.640 0.359 0.000
Z97.8 Presence of other specified devices
0.640 0.360 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.640 0.360 0.000
T93 Sequelae of injuries of lower limb
0.640 0.360 0.000
D03 Melanoma in situ
0.640 0.360 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.640 0.360 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.640 0.360 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.640 0.360 0.000
M77 Other enthesopathies
0.640 0.360 0.000
I09 Other rheumatic heart diseases
0.639 0.361 0.000
I06 Rheumatic aortic valve diseases
0.639 0.361 0.000
K85.1 Biliary acute pancreatitis
0.639 0.361 0.000
E40-E46 Malnutrition
0.639 0.361 0.000
G96 Other disorders of central nervous system
0.638 0.362 0.000
M50 Cervical disk disorders
0.638 0.362 0.000
C80 Malignant neoplasm without specification of site
0.638 0.362 0.000
S62.6 Fracture of other finger
0.637 0.363 0.000
G50 Disorders of trigeminal nerve
0.637 0.363 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.637 0.363 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.637 0.363 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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