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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs116448368
log Bayes Factor = 23.9738
Chromosome 15   position 52,600,590  (GRCh37) Explore rs116448368 on Ensembl!
Variant rs116448368 is part of Cluster X0055

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
K55-K64 Other diseases of intestines
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
1.000 0.000 0.000
B95-B98 Bacterial, viral and other infectious agents
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.999 0.001 0.000
K59 Other functional intestinal disorders
0.999 0.001 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.999 0.001 0.000
K59.0 Constipation
0.998 0.002 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.998 0.002 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.997 0.003 0.000
K80 Cholelithiasis
0.996 0.004 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.995 0.005 0.000
K80.2 Calculus of gallbladder without cholecystitis
0.992 0.008 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.984 0.016 0.000
K56.6 Other and unspecified intestinal obstruction
0.982 0.018 0.000
T81 Complications of procedures, not elsewhere classified
0.981 0.019 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.975 0.025 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.974 0.026 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.969 0.031 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.967 0.033 0.000
I34 Nonrheumatic mitral valve disorders
0.964 0.036 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.964 0.036 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.963 0.037 0.000
K50-K52 Noninfective enteritis and colitis
0.962 0.038 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.962 0.038 0.000
K35-K38 Diseases of appendix
0.962 0.038 0.000
Z45 Adjustment and management of implanted device
0.959 0.041 0.000
R00 Abnormalities of heart beat
0.958 0.042 0.000
Z85 Personal history of malignant neoplasm
0.954 0.046 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.952 0.048 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.950 0.050 0.000
R00.0 Tachycardia, unspecified
0.948 0.052 0.000
Z96 Presence of other functional implants
0.947 0.053 0.000
I51 Complications and ill-defined descriptions of heart disease
0.944 0.056 0.000
Z45.2 Adjustment and management of vascular access device
0.938 0.062 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.936 0.064 0.000
Chapter VIII Diseases of the ear and mastoid process
0.934 0.066 0.000
K35 Acute appendicitis
0.932 0.068 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.931 0.069 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.926 0.074 0.000
R04 Haemorrhage from respiratory passages
0.925 0.075 0.000
Chapter XX External causes of morbidity and mortality
0.924 0.076 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.922 0.078 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.919 0.081 0.000
I05-I09 Chronic rheumatic heart diseases
0.918 0.082 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.918 0.082 0.000
K65-K67 Diseases of peritoneum
0.917 0.083 0.000
K63 Other diseases of intestine
0.917 0.083 0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.917 0.083 0.000
I46 Cardiac arrest
0.916 0.084 0.000
Z95.1 Presence of aortocoronary bypass graft
0.915 0.085 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.914 0.086 0.000
I35 Nonrheumatic aortic valve disorders
0.914 0.086 0.000
Chapter XIV Diseases of the genitourinary system
0.914 0.086 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.910 0.090 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.908 0.092 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.907 0.093 0.000
H90-H95 Other disorders of ear
0.896 0.104 0.000
Z96.8 Presence of other specified functional implants
0.895 0.105 0.000
K51 Ulcerative colitis
0.893 0.107 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.891 0.109 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.887 0.113 0.000
R04.0 Epistaxis
0.886 0.114 0.000
I34.0 Mitral (valve) insufficiency
0.886 0.114 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.879 0.121 0.000
Z93 Artificial opening status
0.877 0.123 0.000
K35.9 Acute appendicitis, unspecified
0.877 0.123 0.000
A30-A49 Other bacterial diseases
0.877 0.123 0.000
I34.1 Mitral (valve) prolapse
0.876 0.124 0.000
Chapter XXII Codes for special purposes
0.874 0.126 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.872 0.128 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.869 0.131 0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems
0.869 0.131 0.000
Z90.7 Acquired absence of genital organ(s)
0.867 0.133 0.000
N10-N16 Renal tubulo-interstitial diseases
0.865 0.135 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.865 0.135 0.000
H91 Other hearing loss
0.863 0.137 0.000
K70-K77 Diseases of liver
0.863 0.137 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.862 0.138 0.000
R00.1 Bradycardia, unspecified
0.861 0.139 0.000
I08 Multiple valve diseases
0.859 0.141 0.000
N60-N64 Disorders of breast
0.858 0.142 0.000
Z96.0 Presence of urogenital implants
0.857 0.143 0.000
K50 Crohn's disease [regional enteritis]
0.855 0.145 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.852 0.148 0.000
Z97 Presence of other devices
0.852 0.148 0.000
K56.5 Intestinal adhesions [bands] with obstruction
0.852 0.148 0.000
Z92 Personal history of medical treatment
0.850 0.150 0.000
K55 Vascular disorders of intestine
0.849 0.151 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.847 0.153 0.000
Z48 Other surgical follow-up care
0.846 0.153 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.845 0.155 0.000
S60-S69 Injuries to the wrist and hand
0.843 0.157 0.000
N13 Obstructive and reflux uropathy
0.842 0.158 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.841 0.159 0.000
H91.9 Hearing loss, unspecified
0.840 0.160 0.000
K83 Other diseases of biliary tract
0.839 0.161 0.000
Chapter V Mental and behavioural disorders
0.839 0.161 0.000
Z90.5 Acquired absence of kidney
0.838 0.162 0.000
I51.7 Cardiomegaly
0.838 0.162 0.000
K56.0 Paralytic ileus
0.838 0.162 0.000
Z45.1 Adjustment and management of infusion pump
0.838 0.162 0.000
S80-S89 Injuries to the knee and lower leg
0.836 0.164 0.000
I38 Endocarditis, valve unspecified
0.834 0.166 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.831 0.169 0.000
Z46 Fitting and adjustment of other devices
0.831 0.169 0.000
I50 Heart failure
0.831 0.169 0.000
I46.0 Cardiac arrest with successful resuscitation
0.831 0.169 0.000
I45 Other conduction disorders
0.830 0.170 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.830 0.170 0.000
Z83 Family history of other specific disorders
0.828 0.172 0.000
I35.0 Aortic (valve) stenosis
0.823 0.177 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.823 0.177 0.000
K86 Other diseases of pancreas
0.820 0.180 0.000
N63 Unspecified lump in breast
0.820 0.180 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.819 0.181 0.000
K63.9 Disease of intestine, unspecified
0.819 0.181 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.814 0.186 0.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.814 0.186 0.000
K40-K46 Hernia
0.809 0.191 0.000
I33 Acute and subacute endocarditis
0.809 0.191 0.000
Z57 Occupational exposure to risk-factors
0.808 0.192 0.000
K66 Other disorders of peritoneum
0.807 0.193 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.806 0.194 0.000
L08 Other local infections of skin and subcutaneous tissue
0.806 0.194 0.000
I49 Other cardiac arrhythmias
0.805 0.195 0.000
K56.1 Intussusception
0.803 0.197 0.000
T79-T79 Certain early complications of trauma
0.801 0.199 0.000
N25-N29 Other disorders of kidney and ureter
0.800 0.200 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.799 0.201 0.000
Z87 Personal history of other diseases and conditions
0.799 0.201 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.798 0.202 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.798 0.202 0.000
K60 Fissure and fistula of anal and rectal regions
0.798 0.202 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.797 0.203 0.000
I51.8 Other ill-defined heart diseases
0.794 0.206 0.000
Chapter VI Diseases of the nervous system
0.794 0.206 0.000
Z90.2 Acquired absence of lung [part of]
0.794 0.206 0.000
N64 Other disorders of breast
0.793 0.207 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.792 0.208 0.000
Z50 Care involving use of rehabilitation procedures
0.791 0.209 0.000
Z48.9 Surgical follow-up care, unspecified
0.790 0.210 0.000
K75 Other inflammatory liver diseases
0.789 0.211 0.000
Z96.2 Presence of otological and audiological implants
0.788 0.212 0.000
I47 Paroxysmal tachycardia
0.786 0.214 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.785 0.215 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.785 0.215 0.000
V10-V19 Pedal cyclist injured in transport accident
0.783 0.217 0.000
K58 Irritable bowel syndrome
0.780 0.220 0.000
Z89 Acquired absence of limb
0.779 0.220 0.000
Z90.3 Acquired absence of part of stomach
0.779 0.221 0.000
K65 Peritonitis
0.778 0.222 0.000
Z60 Problems related to social environment
0.778 0.222 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.778 0.222 0.000
W00-W19 Falls
0.777 0.223 0.000
Z43 Attention to artificial openings
0.776 0.224 0.000
I36 Nonrheumatic tricuspid valve disorders
0.776 0.224 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.775 0.225 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.774 0.226 0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.774 0.226 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.773 0.227 0.000
Z42 Follow-up care involving plastic surgery
0.772 0.228 0.000
B99-B99 Other infectious diseases
0.772 0.228 0.000
S10-S19 Injuries to the neck
0.771 0.229 0.000
K59.8 Other specified functional intestinal disorders
0.770 0.229 0.000
K35.8 Acute appendicitis, other and unspecified
0.770 0.230 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.770 0.230 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.767 0.233 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
0.767 0.233 0.000
L20-L30 Dermatitis and eczema
0.767 0.233 0.000
K61 Abscess of anal and rectal regions
0.767 0.233 0.000
S50-S59 Injuries to the elbow and forearm
0.765 0.235 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.765 0.235 0.000
Z49 Care involving dialysis
0.764 0.236 0.000
I51.9 Heart disease, unspecified
0.764 0.236 0.000
N17-N19 Renal failure
0.763 0.237 0.000
K59.9 Functional intestinal disorder, unspecified
0.762 0.237 0.000
Z95.0 Presence of cardiac pacemaker
0.762 0.238 0.000
L50-L54 Urticaria and erythema
0.761 0.239 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.758 0.242 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.758 0.242 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.758 0.242 0.000
K80.4 Calculus of bile duct with cholecystitis
0.756 0.244 0.000
E65-E68 Obesity and other hyperalimentation
0.756 0.244 0.000
B02 Zoster [herpes zoster]
0.755 0.245 0.000
K51.9 Ulcerative colitis, unspecified
0.754 0.246 0.000
K38 Other diseases of appendix
0.754 0.246 0.000
H93 Other disorders of ear, not elsewhere classified
0.753 0.247 0.000
A41 Other septicaemia
0.753 0.247 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.753 0.247 0.000
S70-S79 Injuries to the hip and thigh
0.752 0.248 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.750 0.250 0.000
K63.8 Other specified diseases of intestine
0.749 0.251 0.000
I42 Cardiomyopathy
0.748 0.252 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.748 0.252 0.000
Z94 Transplanted organ and tissue status
0.744 0.256 0.000
Z95.3 Presence of xenogenic heart valve
0.743 0.257 0.000
R04.2 Haemoptysis
0.743 0.257 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.742 0.258 0.000
K63.3 Ulcer of intestine
0.742 0.258 0.000
K56.2 Volvulus
0.741 0.259 0.000
N99-N99 Other disorders of the genitourinary system
0.741 0.259 0.000
I20-I25 Ischaemic heart diseases
0.740 0.260 0.000
K35.3 Acute appendicitis with localized peritonitis
0.740 0.260 0.000
Z57.2 Occupational exposure to dust
0.737 0.263 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.734 0.266 0.000
I30 Acute pericarditis
0.733 0.267 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.733 0.267 0.000
I46.9 Cardiac arrest, unspecified
0.732 0.267 0.000
W20-W49 Exposure to inanimate mechanical forces
0.731 0.269 0.000
I50.9 Heart failure, unspecified
0.730 0.270 0.000
I35.1 Aortic (valve) insufficiency
0.730 0.270 0.000
R03.1 Nonspecific low blood-pressure reading
0.730 0.270 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.729 0.271 0.000
K55.9 Vascular disorder of intestine, unspecified
0.729 0.271 0.000
E20-E35 Disorders of other endocrine glands
0.729 0.271 0.000
K63.1 Perforation of intestine (nontraumatic)
0.728 0.272 0.000
Z97.8 Presence of other specified devices
0.728 0.272 0.000
K72 Hepatic failure, not elsewhere classified
0.726 0.274 0.000
Z87.4 Personal history of diseases of the genito-urinary system
0.726 0.274 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.724 0.276 0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified
0.724 0.276 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.724 0.276 0.000
R01 Cardiac murmurs and other cardiac sounds
0.723 0.277 0.000
K55.0 Acute vascular disorders of intestine
0.722 0.278 0.000
S64 Injury of nerves at wrist and hand level
0.721 0.279 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.720 0.280 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.718 0.282 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.718 0.282 0.000
F41 Other anxiety disorders
0.718 0.282 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.717 0.283 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.717 0.283 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
Z81 Family history of mental and behavioural disorders
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.717 0.283 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.717 0.283 0.000
B65-B83 Helminthiases
0.717 0.283 0.000
B50-B64 Protozoal diseases
0.717 0.283 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.717 0.283 0.000
B15-B19 Viral hepatitis
0.717 0.283 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.717 0.283 0.000
A75-A79 Rickettsioses
0.717 0.283 0.000
A70-A74 Other diseases caused by chlamydiae
0.717 0.283 0.000
A65-A69 Other spirochaetal diseases
0.717 0.283 0.000
A20-A28 Certain zoonotic bacterial diseases
0.717 0.283 0.000
A15-A19 Tuberculosis
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.716 0.283 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.716 0.284 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.716 0.284 0.000
Z91.6 Personal history of other physical trauma
0.716 0.284 0.000
K59.4 Anal spasm
0.716 0.284 0.000
K59.2 Neurogenic bowel, not elsewhere classified
0.716 0.284 0.000
T87 Complications peculiar to reattachment and amputation
0.716 0.284 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.716 0.284 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.715 0.284 0.000
A80-A89 Viral infections of the central nervous system
0.715 0.284 0.000
R02 Gangrene, not elsewhere classified
0.715 0.285 0.000
K83.0 Cholangitis
0.715 0.285 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.715 0.285 0.000
T86 Failure and rejection of transplanted organs and tissues
0.714 0.286 0.000
K80.3 Calculus of bile duct with cholangitis
0.714 0.286 0.000
K80.8 Other cholelithiasis
0.714 0.286 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.714 0.286 0.000
K56.3 Gallstone ileus
0.713 0.287 0.000
K63.2 Fistula of intestine
0.713 0.287 0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.712 0.288 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.711 0.289 0.000
K66.0 Peritoneal adhesions
0.710 0.290 0.000
R00.2 Palpitations
0.708 0.292 0.000
S40-S49 Injuries to the shoulder and upper arm
0.708 0.292 0.000
K42 Umbilical hernia
0.708 0.292 0.000
E66 Obesity
0.708 0.292 0.000
Z40 Prophylactic surgery
0.707 0.293 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.707 0.293 0.000
S20-S29 Injuries to the thorax
0.707 0.293 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.706 0.294 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.706 0.294 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.706 0.294 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.706 0.294 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.705 0.295 0.000
I45.1 Other and unspecified right bundle-branch block
0.705 0.295 0.000
T66-T78 Other and unspecified effects of external causes
0.704 0.295 0.000
T82.1 Mechanical complication of cardiac electronic device
0.703 0.296 0.000
T81.9 Unspecified complication of procedure
0.703 0.297 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.703 0.297 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.703 0.297 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.703 0.297 0.000
S90-S99 Injuries to the ankle and foot
0.703 0.297 0.000
U80 Agent resistant to penicillin and related antibiotics
0.703 0.297 0.000
K85 Acute pancreatitis
0.703 0.297 0.000
K75.9 Inflammatory liver disease, unspecified
0.703 0.297 0.000
Z93.2 Ileostomy status
0.703 0.297 0.000
X50-X57 Overexertion, travel and privation
0.702 0.298 0.000
N64.5 Other signs and symptoms in breast
0.702 0.298 0.000
L03 Cellulitis
0.701 0.299 0.000
N13.8 Other obstructive and reflux uropathy
0.701 0.299 0.000
K51.8 Other ulcerative colitis
0.701 0.299 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.701 0.299 0.000
H80-H83 Diseases of inner ear
0.701 0.299 0.000
K35.1 Acute appendicitis with peritoneal abscess
0.700 0.299 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.700 0.300 0.000
Y43 Primarily systemic agents
0.699 0.300 0.000
Z93.5 Cystostomy status
0.699 0.301 0.000
Z54 Convalescence
0.699 0.301 0.000
Z52 Donors of organs and tissues
0.699 0.301 0.000
Z44 Fitting and adjustment of external prosthetic device
0.699 0.301 0.000
K50.1 Crohn's disease of large intestine
0.698 0.302 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.698 0.302 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.698 0.302 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.698 0.302 0.000
T82.3 Mechanical complication of other vascular grafts
0.698 0.302 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.698 0.302 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.698 0.302 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.698 0.302 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.698 0.302 0.000
Z46.6 Fitting and adjustment of urinary device
0.698 0.302 0.000
H60-H62 Diseases of external ear
0.696 0.304 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.696 0.304 0.000
K52 Other non-infective gastro-enteritis and colitis
0.695 0.305 0.000
I31 Other diseases of pericardium
0.695 0.305 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.695 0.305 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.695 0.305 0.000
Z97.4 Presence of external hearing-aid
0.695 0.305 0.000
Z93.6 Other artificial openings of urinary tract status
0.695 0.305 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.694 0.306 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.694 0.306 0.000
L10-L14 Bullous disorders
0.693 0.307 0.000
Z98 Other postsurgical states
0.693 0.307 0.000
K51.4 Pseudopolyposis of colon
0.693 0.307 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.692 0.308 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.691 0.308 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.691 0.308 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.691 0.308 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.691 0.309 0.000
K36 Other appendicitis
0.689 0.310 0.000
Z45.9 Adjustment and management of unspecified implanted device
0.687 0.313 0.000
Z45.3 Adjustment and management of implanted hearing device
0.687 0.313 0.000
Z95.4 Presence of other heart-valve replacement
0.687 0.313 0.000
I49.5 Sick sinus syndrome
0.686 0.314 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.686 0.314 0.000
N18 Chronic renal failure
0.686 0.314 0.000
K50.9 Crohn's disease, unspecified
0.685 0.315 0.000
Z85.0 Personal history of malignant neoplasm of digestive organs
0.684 0.316 0.000
Z85.9 Personal history of malignant neoplasm, unspecified
0.684 0.316 0.000
Z92.8 Personal history of other medical treatment
0.684 0.316 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.684 0.316 0.000
Z85.5 Personal history of malignant neoplasm of urinary tract
0.684 0.316 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.682 0.318 0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures
0.682 0.318 0.000
N00-N08 Glomerular diseases
0.682 0.318 0.000
N13.3 Other and unspecified hydronephrosis
0.680 0.320 0.000
Z90.0 Acquired absence of part of head and neck
0.680 0.320 0.000
A46 Erysipelas
0.679 0.321 0.000
Z96.9 Presence of functional implant, unspecified
0.679 0.321 0.000
Z96.7 Presence of other bone and tendon implants
0.679 0.321 0.000
Z96.5 Presence of tooth-root and mandibular implants
0.679 0.321 0.000
Z96.4 Presence of endocrine implants
0.679 0.321 0.000
Z96.3 Presence of artificial larynx
0.679 0.321 0.000
Z33 Pregnant state, incidental
0.679 0.321 0.000
B02.9 Zoster without complication
0.679 0.321 0.000
K41 Femoral hernia
0.679 0.321 0.000
K65.0 Acute peritonitis
0.678 0.322 0.000
Z60.2 Living alone
0.678 0.322 0.000
I51.6 Cardiovascular disease, unspecified
0.677 0.323 0.000
I51.5 Myocardial degeneration
0.677 0.323 0.000
I51.4 Myocarditis, unspecified
0.677 0.323 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.677 0.323 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.677 0.323 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.677 0.323 0.000
I51.0 Cardiac septal defect, acquired
0.677 0.323 0.000
E66.8 Other obesity
0.677 0.323 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.676 0.324 0.000
N13.6 Pyonephrosis
0.676 0.324 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.676 0.324 0.000
Z93.1 Gastrostomy status
0.675 0.325 0.000
S89 Other and unspecified injuries of lower leg
0.675 0.325 0.000
X60-X84 Intentional self-harm
0.673 0.327 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.673 0.327 0.000
S82 Fracture of lower leg, including ankle
0.673 0.327 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.673 0.327 0.000
K60.1 Chronic anal fissure
0.673 0.327 0.000
I33.0 Acute and subacute infective endocarditis
0.672 0.328 0.000
K50.0 Crohn's disease of small intestine
0.672 0.328 0.000
L04 Acute lymphadenitis
0.671 0.329 0.000
L01 Impetigo
0.671 0.329 0.000
L00 Staphylococcal scalded skin syndrome
0.671 0.329 0.000
I05 Rheumatic mitral valve diseases
0.671 0.329 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.671 0.329 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.671 0.329 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.670 0.330 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.670 0.330 0.000
K86.1 Other chronic pancreatitis
0.669 0.331 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.668 0.332 0.000
K35.2 Acute appendicitis with generalized peritonitis
0.668 0.332 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.667 0.333 0.000
L05 Pilonidal cyst
0.666 0.333 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.666 0.334 0.000
I49.0 Ventricular fibrillation and flutter
0.666 0.334 0.000
Z83.5 Family history of eye and ear disorders
0.665 0.335 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.664 0.336 0.000
K35.0 Acute appendicitis with generalised peritonitis
0.664 0.336 0.000
K56.4 Other impaction of intestine
0.664 0.336 0.000
Z83.7 Family history of diseases of the digestive system
0.663 0.337 0.000
R04.9 Haemorrhage from respiratory passages, unspecified
0.663 0.337 0.000
R04.8 Haemorrhage from other sites in respiratory passages
0.663 0.337 0.000
R04.1 Haemorrhage from throat
0.663 0.337 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.663 0.337 0.000
Y35-Y36 Legal intervention and operations of war
0.663 0.337 0.000
Y10-Y34 Event of undetermined intent
0.663 0.337 0.000
Y00-Y09 Assault
0.663 0.337 0.000
X85-X99 Assault
0.663 0.337 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.663 0.337 0.000
X30-X39 Exposure to forces of nature
0.663 0.337 0.000
X20-X29 Contact with venomous animals and plants
0.663 0.337 0.000
X10-X19 Contact with heat and hot substances
0.663 0.337 0.000
X00-X09 Exposure to smoke, fire and flames
0.663 0.337 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.663 0.337 0.000
W75-W84 Other accidental threats to breathing
0.663 0.337 0.000
W65-W74 Accidental drowning and submersion
0.663 0.337 0.000
W50-W64 Exposure to animate mechanical forces
0.663 0.337 0.000
V98-V99 Other and unspecified transport accidents
0.663 0.337 0.000
V95-V97 Air and space transport accidents
0.663 0.337 0.000
V90-V94 Water transport accidents
0.663 0.337 0.000
V80-V89 Other land transport accidents
0.663 0.337 0.000
V70-V79 Bus occupant injured in transport accident
0.663 0.337 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.663 0.337 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.663 0.337 0.000
V40-V49 Car occupant injured in transport accident
0.663 0.337 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.663 0.337 0.000
V20-V29 Motorcycle rider injured in transport accident
0.663 0.337 0.000
V01-V09 Pedestrian injured in transport accident
0.663 0.337 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.662 0.338 0.000
R79 Other abnormal findings of blood chemistry
0.661 0.339 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.661 0.339 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.660 0.340 0.000
A41.9 Septicaemia, unspecified
0.660 0.340 0.000
K46 Unspecified abdominal hernia
0.660 0.340 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.659 0.341 0.000
K59.3 Megacolon, not elsewhere classified
0.659 0.341 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.659 0.341 0.000
T85.2 Mechanical complication of intraocular lens
0.659 0.341 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.659 0.341 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.659 0.341 0.000
I09 Other rheumatic heart diseases
0.658 0.342 0.000
I06 Rheumatic aortic valve diseases
0.658 0.342 0.000
Z65 Problems related to other psychosocial circumstances
0.658 0.342 0.000
Z64 Problems related to certain psychosocial circumstances
0.658 0.342 0.000
Z63 Other problems related to primary support group, including family circumstances
0.658 0.342 0.000
Z62 Other problems related to upbringing
0.658 0.342 0.000
Z61 Problems related to negative life events in childhood
0.658 0.342 0.000
Z59 Problems related to housing and economic circumstances
0.658 0.342 0.000
Z58 Problems related to physical environment
0.658 0.342 0.000
Z56 Problems related to employment and unemployment
0.658 0.342 0.000
Z55 Problems related to education and literacy
0.658 0.342 0.000
K67 Disorders of peritoneum in infectious diseases classified elsewhere
0.658 0.342 0.000
K63.4 Enteroptosis
0.657 0.342 0.000
K63.0 Abscess of intestine
0.657 0.342 0.000
I46.1 Sudden cardiac death, so described
0.657 0.343 0.000
Z96.1 Presence of intraocular lens
0.656 0.344 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.655 0.344 0.000
K83.8 Other specified diseases of biliary tract
0.655 0.345 0.000
I35.9 Aortic valve disorder, unspecified
0.655 0.345 0.000
I35.8 Other aortic valve disorders
0.655 0.345 0.000
I08.0 Disorders of both mitral and aortic valves
0.655 0.345 0.000
N28.8 Other specified disorders of kidney and ureter
0.655 0.345 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.655 0.345 0.000
A49 Bacterial infection of unspecified site
0.654 0.345 0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters
0.654 0.346 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.653 0.347 0.000
N64.8 Other specified disorders of breast
0.653 0.347 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.653 0.347 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.652 0.348 0.000
F41.2 Mixed anxiety and depressive disorder
0.652 0.348 0.000
H93.1 Tinnitus
0.651 0.349 0.000
Z43.2 Attention to ileostomy
0.650 0.350 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.649 0.351 0.000
Z90.8 Acquired absence of other organs
0.648 0.351 0.000
R47-R49 Symptoms and signs involving speech and voice
0.648 0.352 0.000
Y40 Systemic antibiotics
0.647 0.353 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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