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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77943567
log Bayes Factor = 12.8021
Chromosome 4   position 802,144  (GRCh37) Explore rs77943567 on Ensembl!
Variant rs77943567 is part of Cluster X0258

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.999 0.001 0.000
N73 Other female pelvic inflammatory diseases
0.997 0.003 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.996 0.004 0.000
I50 Heart failure
0.996 0.004 0.000
I42 Cardiomyopathy
0.996 0.004 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.995 0.005 0.000
M23 Internal derangement of knee
0.992 0.008 0.000
N73.6 Female pelvic peritoneal adhesions
0.991 0.009 0.000
N72 Inflammatory disease of cervix uteri
0.990 0.010 0.000
Chapter II Neoplasms
0.988 0.012 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.981 0.019 0.000
N10-N16 Renal tubulo-interstitial diseases
0.981 0.019 0.000
C79 Secondary malignant neoplasm of other sites
0.980 0.020 0.000
C78.7 Secondary malignant neoplasm of liver
0.973 0.027 0.000
I50.0 Congestive heart failure
0.972 0.028 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.971 0.029 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.965 0.035 0.000
N13 Obstructive and reflux uropathy
0.964 0.036 0.000
M05-M14 Inflammatory polyarthropathies
0.962 0.038 0.000
I35 Nonrheumatic aortic valve disorders
0.959 0.041 0.000
I34 Nonrheumatic mitral valve disorders
0.956 0.044 0.000
M20 Acquired deformities of fingers and toes
0.952 0.048 0.000
M06 Other rheumatoid arthritis
0.949 0.051 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.948 0.052 0.000
M25 Other joint disorders, not elsewhere classified
0.947 0.053 0.000
I42.9 Cardiomyopathy, unspecified
0.944 0.056 0.000
I50.9 Heart failure, unspecified
0.937 0.063 0.000
M70-M79 Other soft tissue disorders
0.937 0.063 0.000
N17-N19 Renal failure
0.935 0.065 0.000
C78.2 Secondary malignant neoplasm of pleura
0.934 0.066 0.000
I51 Complications and ill-defined descriptions of heart disease
0.931 0.069 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.930 0.070 0.000
M06.9 Rheumatoid arthritis, unspecified
0.929 0.071 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.927 0.073 0.000
N20-N23 Urolithiasis
0.926 0.074 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.924 0.076 0.000
I51.9 Heart disease, unspecified
0.921 0.079 0.000
Q80-Q89 Other congenital malformations
0.917 0.083 0.000
I42.0 Dilated cardiomyopathy
0.916 0.084 0.000
N13.3 Other and unspecified hydronephrosis
0.908 0.092 0.000
I05-I09 Chronic rheumatic heart diseases
0.901 0.099 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.900 0.100 0.000
I95 Hypotension
0.899 0.101 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.898 0.102 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.897 0.103 0.000
N20 Calculus of kidney and ureter
0.896 0.104 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.896 0.104 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.895 0.105 0.000
M24 Other specific joint derangements
0.894 0.106 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.894 0.106 0.000
I34.1 Mitral (valve) prolapse
0.894 0.106 0.000
I35.1 Aortic (valve) insufficiency
0.893 0.107 0.000
I27 Other pulmonary heart diseases
0.893 0.107 0.000
C78.0 Secondary malignant neoplasm of lung
0.892 0.108 0.000
I38 Endocarditis, valve unspecified
0.891 0.109 0.000
N85.2 Hypertrophy of uterus
0.888 0.112 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.887 0.113 0.000
N73.9 Female pelvic inflammatory disease, unspecified
0.887 0.113 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.886 0.114 0.000
M91-M94 Chondropathies
0.886 0.114 0.000
S00-S09 Injuries to the head
0.883 0.117 0.000
Chapter XX External causes of morbidity and mortality
0.882 0.118 0.000
M23.8 Other internal derangements of knee
0.873 0.127 0.000
M20.4 Other hammer toe(s) (acquired)
0.869 0.131 0.000
N25-N29 Other disorders of kidney and ureter
0.861 0.139 0.000
I42.2 Other hypertrophic cardiomyopathy
0.860 0.140 0.000
E20-E35 Disorders of other endocrine glands
0.859 0.141 0.000
M77 Other enthesopathies
0.857 0.143 0.000
N18 Chronic renal failure
0.855 0.145 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.855 0.145 0.000
O60-O75 Complications of labour and delivery
0.851 0.149 0.000
M20.1 Hallux valgus (acquired)
0.848 0.152 0.000
I42.8 Other cardiomyopathies
0.847 0.153 0.000
N20.1 Calculus of ureter
0.846 0.154 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.844 0.156 0.000
S05 Injury of eye and orbit
0.843 0.157 0.000
M79.6 Pain in limb
0.842 0.158 0.000
I08 Multiple valve diseases
0.842 0.158 0.000
I50.1 Left ventricular failure
0.837 0.163 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.837 0.163 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.836 0.164 0.000
N19 Unspecified renal failure
0.833 0.167 0.000
M65-M68 Disorders of synovium and tendon
0.829 0.171 0.000
C64-C68 Malignant neoplasms of urinary tract
0.829 0.171 0.000
M21 Other acquired deformities of limbs
0.829 0.171 0.000
N13.8 Other obstructive and reflux uropathy
0.829 0.171 0.000
M23.9 Internal derangement of knee, unspecified
0.829 0.171 0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems
0.829 0.171 0.000
M31 Other necrotising vasculopathies
0.823 0.177 0.000
Q60-Q64 Congenital malformations of the urinary system
0.822 0.178 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.820 0.180 0.000
C15-C26 Malignant neoplasms of digestive organs
0.819 0.181 0.000
M25.7 Osteophyte
0.819 0.181 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.817 0.183 0.000
M80-M85 Disorders of bone density and structure
0.816 0.184 0.000
I27.0 Primary pulmonary hypertension
0.815 0.185 0.000
N18.9 Chronic renal failure, unspecified
0.814 0.186 0.000
S00 Superficial injury of head
0.814 0.186 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.813 0.187 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.813 0.187 0.000
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.811 0.189 0.000
I34.0 Mitral (valve) insufficiency
0.810 0.190 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.808 0.191 0.000
M25.5 Pain in joint
0.806 0.194 0.000
N89 Other noninflammatory disorders of vagina
0.805 0.195 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.805 0.195 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.804 0.196 0.000
I35.0 Aortic (valve) stenosis
0.802 0.198 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.801 0.199 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.800 0.200 0.000
I95.9 Hypotension, unspecified
0.800 0.200 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.800 0.200 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.800 0.200 0.000
N99-N99 Other disorders of the genitourinary system
0.799 0.201 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.799 0.201 0.000
I27.2 Other secondary pulmonary hypertension
0.798 0.202 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.796 0.204 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.794 0.206 0.000
M94 Other disorders of cartilage
0.792 0.208 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.791 0.209 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.789 0.211 0.000
Q82 Other congenital malformations of skin
0.788 0.212 0.000
N84 Polyp of female genital tract
0.787 0.213 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.785 0.215 0.000
E00-E07 Disorders of thyroid gland
0.783 0.217 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.782 0.218 0.000
Y60.0 During surgical operation
0.782 0.218 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.780 0.220 0.000
M06.0 Seronegative rheumatoid arthritis
0.778 0.222 0.000
Chapter V Mental and behavioural disorders
0.777 0.223 0.000
Q00-Q07 Congenital malformations of the nervous system
0.773 0.227 0.000
M00-M03 Infectious arthropathies
0.773 0.227 0.000
M25.3 Other instability of joint
0.772 0.228 0.000
M79.7 Fibromyalgia
0.772 0.228 0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)
0.770 0.230 0.000
I31 Other diseases of pericardium
0.769 0.231 0.000
N26 Unspecified contracted kidney
0.769 0.231 0.000
Q87.4 Marfan's syndrome
0.765 0.235 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.765 0.235 0.000
C67 Malignant neoplasm of bladder
0.764 0.236 0.000
M23.5 Chronic instability of knee
0.764 0.236 0.000
I46 Cardiac arrest
0.763 0.237 0.000
M34 Systemic sclerosis
0.763 0.237 0.000
N71 Inflammatory disease of uterus, except cervix
0.762 0.238 0.000
Q50-Q56 Congenital malformations of genital organs
0.762 0.238 0.000
N83.2 Other and unspecified ovarian cysts
0.761 0.239 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.761 0.239 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.759 0.241 0.000
N85.8 Other specified noninflammatory disorders of uterus
0.758 0.242 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.758 0.242 0.000
C16 Malignant neoplasm of stomach
0.757 0.243 0.000
M06.4 Inflammatory polyarthropathy
0.756 0.244 0.000
C79.2 Secondary malignant neoplasm of skin
0.753 0.247 0.000
S01 Open wound of head
0.753 0.247 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.752 0.248 0.000
V80-V89 Other land transport accidents
0.750 0.250 0.000
M79.62 Pain in limb (Upper arm)
0.749 0.251 0.000
N13.4 Hydroureter
0.748 0.252 0.000
N85.1 Endometrial adenomatous hyperplasia
0.747 0.253 0.000
I44 Atrioventricular and left bundle-branch block
0.747 0.253 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.745 0.255 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.745 0.255 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.744 0.256 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.744 0.256 0.000
I95.2 Hypotension due to drugs
0.744 0.256 0.000
O66 Other obstructed labour
0.744 0.256 0.000
M45-M49 Spondylopathies
0.743 0.256 0.000
O61 Failed induction of labour
0.743 0.257 0.000
M79.67 Pain in limb (Ankle and foot)
0.742 0.258 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.741 0.259 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.741 0.259 0.000
M23.4 Loose body in knee
0.738 0.262 0.000
M60-M63 Disorders of muscles
0.738 0.262 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.738 0.262 0.000
N82 Fistulae involving female genital tract
0.737 0.263 0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified
0.737 0.263 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.737 0.263 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.736 0.264 0.000
N20.0 Calculus of kidney
0.734 0.266 0.000
I95.1 Orthostatic hypotension
0.734 0.266 0.000
S05.1 Contusion of eyeball and orbital tissues
0.734 0.266 0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body
0.734 0.266 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.733 0.267 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.732 0.268 0.000
I42.6 Alcoholic cardiomyopathy
0.732 0.268 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.731 0.269 0.000
O85-O92 Complications predominantly related to the puerperium
0.731 0.269 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.730 0.270 0.000
I36 Nonrheumatic tricuspid valve disorders
0.730 0.270 0.000
S00.9 Superficial injury of head, part unspecified
0.730 0.270 0.000
I37 Pulmonary valve disorders
0.729 0.271 0.000
M79.69 Pain in limb (Site unspecified)
0.728 0.272 0.000
M24.2 Disorder of ligament
0.725 0.275 0.000
M86-M90 Other osteopathies
0.725 0.275 0.000
N84.0 Polyp of corpus uteri
0.724 0.276 0.000
M77.1 Lateral epicondylitis
0.722 0.277 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.721 0.278 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.720 0.280 0.000
S06 Intracranial injury
0.719 0.281 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.718 0.282 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
M33 Dermatopolymyositis
0.717 0.283 0.000
M32 Systemic lupus erythematosus
0.717 0.283 0.000
M30 Polyarteritis nodosa and related conditions
0.717 0.283 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.717 0.283 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.716 0.284 0.000
N73.8 Other specified female pelvic inflammatory diseases
0.714 0.285 0.000
N73.5 Female pelvic peritonitis, unspecified
0.714 0.285 0.000
N73.4 Female chronic pelvic peritonitis
0.714 0.285 0.000
N73.3 Female acute pelvic peritonitis
0.714 0.285 0.000
N73.2 Unspecified parametritis and pelvic cellulitis
0.714 0.285 0.000
N73.1 Chronic parametritis and pelvic cellulitis
0.714 0.285 0.000
N73.0 Acute parametritis and pelvic cellulitis
0.714 0.285 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.714 0.286 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.714 0.286 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.714 0.286 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.714 0.286 0.000
I42.5 Other restrictive cardiomyopathy
0.714 0.286 0.000
I42.4 Endocardial fibroelastosis
0.714 0.286 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.714 0.286 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.713 0.287 0.000
M20.2 Hallux rigidus
0.713 0.287 0.000
M76 Enthesopathies of lower limb, excluding foot
0.713 0.287 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.712 0.288 0.000
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)
0.712 0.288 0.000
M23.1 Discoid meniscus (congenital)
0.711 0.289 0.000
M23.0 Cystic meniscus
0.711 0.289 0.000
M25.56 Pain in joint (Lower leg)
0.711 0.289 0.000
N13.6 Pyonephrosis
0.710 0.290 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.709 0.291 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.708 0.292 0.000
M65 Synovitis and tenosynovitis
0.708 0.292 0.000
M25.0 Haemarthrosis
0.708 0.292 0.000
E28 Ovarian dysfunction
0.708 0.292 0.000
S05.3 Ocular laceration without prolapse or loss of intraocular tissue
0.708 0.292 0.000
N11 Chronic tubulo-interstitial nephritis
0.707 0.293 0.000
N20.9 Urinary calculus, unspecified
0.707 0.293 0.000
M25.9 Joint disorder, unspecified
0.707 0.293 0.000
N85.9 Noninflammatory disorder of uterus, unspecified
0.707 0.293 0.000
M13 Other arthritis
0.707 0.293 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.706 0.294 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.705 0.295 0.000
I51.4 Myocarditis, unspecified
0.705 0.295 0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.705 0.295 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.704 0.296 0.000
M24.1 Other articular cartilage disorders
0.704 0.296 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.703 0.296 0.000
Q35-Q37 Cleft lip and cleft palate
0.703 0.296 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.703 0.296 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.703 0.296 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.703 0.297 0.000
N15 Other renal tubulo-interstitial diseases
0.703 0.297 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.703 0.297 0.000
N85.6 Intra-uterine synechiae
0.703 0.297 0.000
C79.6 Secondary malignant neoplasm of ovary
0.703 0.297 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.703 0.297 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.703 0.297 0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)
0.703 0.297 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.701 0.299 0.000
M94.8 Other specified disorders of cartilage
0.701 0.299 0.000
M79.61 Pain in limb (Shoulder region)
0.701 0.299 0.000
M05 Seropositive rheumatoid arthritis
0.701 0.299 0.000
F10.3 Withdrawal state
0.701 0.299 0.000
E21.0 Primary hyperparathyroidism
0.700 0.300 0.000
C80 Malignant neoplasm without specification of site
0.700 0.300 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.698 0.302 0.000
N89.8 Other specified noninflammatory disorders of vagina
0.698 0.302 0.000
E24 Cushing's syndrome
0.698 0.302 0.000
F10.2 Dependence syndrome
0.697 0.303 0.000
Q63 Other congenital malformations of kidney
0.697 0.303 0.000
M72 Fibroblastic disorders
0.695 0.305 0.000
I33 Acute and subacute endocarditis
0.695 0.305 0.000
N70 Salpingitis and oophoritis
0.694 0.306 0.000
O70 Perineal laceration during delivery
0.694 0.306 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.692 0.308 0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular
0.692 0.308 0.000
M77.4 Metatarsalgia
0.691 0.309 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.691 0.309 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.691 0.309 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.690 0.309 0.000
M14 Arthropathies in other diseases classified elsewhere
0.690 0.310 0.000
M12 Other specific arthropathies
0.690 0.310 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.690 0.310 0.000
M08 Juvenile arthritis
0.690 0.310 0.000
M25.72 Osteophyte (Upper arm)
0.690 0.310 0.000
I05 Rheumatic mitral valve diseases
0.689 0.311 0.000
M23.80 Other internal derangements of knee (Multiple sites)
0.689 0.311 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.688 0.312 0.000
N18.3 Chronic kidney disease, stage 3
0.688 0.312 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.688 0.312 0.000
E21.3 Hyperparathyroidism, unspecified
0.688 0.312 0.000
X20-X29 Contact with venomous animals and plants
0.686 0.314 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.686 0.314 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.686 0.314 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.686 0.314 0.000
C25 Malignant neoplasm of pancreas
0.685 0.315 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.684 0.316 0.000
O16 Unspecified maternal hypertension
0.684 0.316 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.684 0.316 0.000
I35.9 Aortic valve disorder, unspecified
0.683 0.317 0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis
0.682 0.318 0.000
L20-L30 Dermatitis and eczema
0.681 0.319 0.000
M06.8 Other specified rheumatoid arthritis
0.680 0.319 0.000
M06.3 Rheumatoid nodule
0.680 0.319 0.000
M06.2 Rheumatoid bursitis
0.680 0.319 0.000
M06.1 Adult-onset Still's disease
0.680 0.319 0.000
X60-X84 Intentional self-harm
0.680 0.320 0.000
C16.9 Stomach, unspecified
0.680 0.320 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.679 0.321 0.000
M25.2 Flail joint
0.679 0.321 0.000
M25.1 Fistula of joint
0.679 0.321 0.000
M25.77 Osteophyte (Ankle and foot)
0.679 0.321 0.000
I35.8 Other aortic valve disorders
0.677 0.322 0.000
I08.0 Disorders of both mitral and aortic valves
0.675 0.325 0.000
M31.6 Other giant cell arteritis
0.674 0.326 0.000
M07 Psoriatic and enteropathic arthropathies
0.674 0.326 0.000
C71 Malignant neoplasm of brain
0.673 0.327 0.000
M40-M43 Deforming dorsopathies
0.673 0.327 0.000
S10-S19 Injuries to the neck
0.673 0.327 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.672 0.328 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.672 0.328 0.000
O73 Retained placenta and membranes, without haemorrhage
0.672 0.328 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.672 0.328 0.000
N20.2 Calculus of kidney with calculus of ureter
0.671 0.329 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.670 0.329 0.000
N91 Absent, scanty and rare menstruation
0.669 0.330 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.669 0.330 0.000
M25.4 Effusion of joint
0.669 0.331 0.000
C67.6 Ureteric orifice
0.669 0.331 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.668 0.331 0.000
I51.6 Cardiovascular disease, unspecified
0.668 0.331 0.000
M23.3 Other meniscus derangements
0.668 0.332 0.000
N27 Small kidney of unknown cause
0.668 0.332 0.000
I51.5 Myocardial degeneration
0.668 0.332 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.668 0.332 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.668 0.332 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.668 0.332 0.000
I51.0 Cardiac septal defect, acquired
0.668 0.332 0.000
M77.9 Enthesopathy, unspecified
0.667 0.332 0.000
E70-E90 Metabolic disorders
0.668 0.332 0.000
S00.8 Superficial injury of other parts of head
0.667 0.333 0.000
I95.8 Other hypotension
0.667 0.333 0.000
I28 Other diseases of pulmonary vessels
0.667 0.333 0.000
M77.0 Medial epicondylitis
0.666 0.333 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.666 0.334 0.000
O61.0 Failed medical induction of labour
0.666 0.334 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.666 0.334 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.666 0.334 0.000
E05.9 Thyrotoxicosis, unspecified
0.666 0.334 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.665 0.335 0.000
I27.9 Pulmonary heart disease, unspecified
0.664 0.335 0.000
M25.74 Osteophyte (Hand)
0.664 0.336 0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified
0.664 0.336 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.664 0.336 0.000
S00.3 Superficial injury of nose
0.664 0.336 0.000
S90-S99 Injuries to the ankle and foot
0.663 0.337 0.000
L40-L45 Papulosquamous disorders
0.663 0.337 0.000
M79.2 Neuralgia and neuritis, unspecified
0.663 0.337 0.000
I47 Paroxysmal tachycardia
0.663 0.337 0.000
Y44 Agents primarily affecting blood constituents
0.662 0.338 0.000
M21.0 Valgus deformity, not elsewhere classified
0.662 0.338 0.000
M20.0 Deformity of finger(s)
0.661 0.339 0.000
Q85 Phakomatoses, not elsewhere classified
0.661 0.339 0.000
Q82.8 Other specified congenital malformations of skin
0.661 0.339 0.000
E22 Hyperfunction of pituitary gland
0.660 0.340 0.000
M92 Other juvenile osteochondrosis
0.659 0.341 0.000
Chapter XXII Codes for special purposes
0.658 0.341 0.000
I30 Acute pericarditis
0.658 0.342 0.000
T00-T07 Injuries involving multiple body regions
0.658 0.342 0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified
0.657 0.342 0.000
Q84 Other congenital malformations of integument
0.657 0.342 0.000
Q83 Congenital malformations of breast
0.657 0.342 0.000
Q81 Epidermolysis bullosa
0.657 0.342 0.000
Q80 Congenital ichthyosis
0.657 0.342 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.655 0.345 0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified
0.655 0.345 0.000
N89.5 Stricture and atresia of vagina
0.653 0.347 0.000
S01.8 Open wound of other parts of head
0.653 0.347 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.652 0.348 0.000
O71 Other obstetric trauma
0.652 0.348 0.000
M94.86 Other specified disorders of cartilage (Lower leg)
0.651 0.349 0.000
L30 Other dermatitis
0.651 0.349 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.650 0.349 0.000
M84 Disorders of continuity of bone
0.650 0.350 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.650 0.350 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.649 0.351 0.000
E40-E46 Malnutrition
0.649 0.351 0.000
M79.8 Other specified soft tissue disorders
0.649 0.351 0.000
M79.79 Fibromyalgia (Site unspecified)
0.649 0.351 0.000
M93 Other osteochondropathies
0.647 0.353 0.000
M25.37 Other instability of joint (Ankle and foot)
0.647 0.353 0.000
I09 Other rheumatic heart diseases
0.646 0.354 0.000
I06 Rheumatic aortic valve diseases
0.646 0.354 0.000
I46.9 Cardiac arrest, unspecified
0.646 0.354 0.000
E07 Other disorders of thyroid
0.646 0.354 0.000
N18.5 Chronic kidney disease, stage 5
0.646 0.354 0.000
I95.0 Idiopathic hypotension
0.644 0.356 0.000
N98 Complications associated with artificial fertilisation
0.644 0.356 0.000
N96 Habitual aborter
0.644 0.356 0.000
M46 Other inflammatory spondylopathies
0.644 0.356 0.000
N85.4 Malposition of uterus
0.643 0.357 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.643 0.357 0.000
I44.7 Left bundle-branch block, unspecified
0.642 0.358 0.000
T33-T35 Frostbite
0.642 0.358 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.642 0.358 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.642 0.358 0.000
M21.2 Flexion deformity
0.642 0.358 0.000
N85.7 Haematometra
0.642 0.358 0.000
N85.5 Inversion of uterus
0.642 0.358 0.000
N85.3 Subinvolution of uterus
0.642 0.358 0.000
C67.2 Lateral wall of bladder
0.642 0.358 0.000
C23 Malignant neoplasm of gallbladder
0.641 0.359 0.000
M24.9 Joint derangement, unspecified
0.641 0.359 0.000
M24.7 Protrusio acetabuli
0.641 0.359 0.000
M24.6 Ankylosis of joint
0.641 0.359 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.641 0.359 0.000
X50-X57 Overexertion, travel and privation
0.641 0.359 0.000
Q89 Other congenital malformations, not elsewhere classified
0.641 0.359 0.000
M79.9 Soft tissue disorder, unspecified
0.641 0.359 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.641 0.359 0.000
M79.3 Panniculitis, unspecified
0.641 0.359 0.000
I27.8 Other specified pulmonary heart diseases
0.640 0.360 0.000
I27.1 Kyphoscoliotic heart disease
0.640 0.360 0.000
C67.4 Posterior wall of bladder
0.640 0.360 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.639 0.361 0.000
I45 Other conduction disorders
0.638 0.362 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.637 0.363 0.000
I31.9 Disease of pericardium, unspecified
0.637 0.363 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.637 0.363 0.000
M21.4 Flat foot [pes planus] (acquired)
0.637 0.363 0.000
M25.59 Pain in joint (Site unspecified)
0.636 0.364 0.000
E23 Hypofunction and other disorders of pituitary gland
0.636 0.364 0.000
M25.57 Pain in joint (Ankle and foot)
0.636 0.364 0.000
M91 Juvenile osteochondrosis of hip and pelvis
0.635 0.365 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.634 0.366 0.000
W20-W49 Exposure to inanimate mechanical forces
0.634 0.366 0.000
S08 Traumatic amputation of part of head
0.633 0.367 0.000
S07 Crushing injury of head
0.633 0.367 0.000
S04 Injury of cranial nerves
0.633 0.367 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.633 0.367 0.000
V40-V49 Car occupant injured in transport accident
0.633 0.367 0.000
N83.1 Corpus luteum cyst
0.632 0.367 0.000
M79.5 Residual foreign body in soft tissue
0.632 0.368 0.000
Y35-Y36 Legal intervention and operations of war
0.632 0.368 0.000
Y10-Y34 Event of undetermined intent
0.632 0.368 0.000
Y00-Y09 Assault
0.632 0.368 0.000
X85-X99 Assault
0.632 0.368 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.632 0.368 0.000
X30-X39 Exposure to forces of nature
0.632 0.368 0.000
X10-X19 Contact with heat and hot substances
0.632 0.368 0.000
X00-X09 Exposure to smoke, fire and flames
0.632 0.368 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.632 0.368 0.000
W75-W84 Other accidental threats to breathing
0.632 0.368 0.000
W65-W74 Accidental drowning and submersion
0.632 0.368 0.000
V98-V99 Other and unspecified transport accidents
0.632 0.368 0.000
V95-V97 Air and space transport accidents
0.632 0.368 0.000
V90-V94 Water transport accidents
0.632 0.368 0.000
V70-V79 Bus occupant injured in transport accident
0.632 0.368 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.632 0.368 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.632 0.368 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.632 0.368 0.000
V01-V09 Pedestrian injured in transport accident
0.632 0.368 0.000
M24.5 Contracture of joint
0.631 0.368 0.000
C67.1 Dome of bladder
0.631 0.369 0.000
N71.9 Inflammatory disease of uterus, unspecified
0.631 0.369 0.000
Q07 Other congenital malformations of nervous system
0.631 0.369 0.000
L30.9 Dermatitis, unspecified
0.629 0.371 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.629 0.371 0.000
M99 Biomechanical lesions, not elsewhere classified
0.627 0.373 0.000
M25.78 Osteophyte (Other)
0.627 0.373 0.000
M20.3 Other deformity of hallux (acquired)
0.627 0.373 0.000
Q82.5 Congenital nonneoplastic naevus
0.627 0.373 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.626 0.373 0.000
M31.3 Wegener's granulomatosis
0.626 0.374 0.000
M23.87 Other internal derangements of knee (Capsular ligament)
0.626 0.374 0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)
0.626 0.374 0.000
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)
0.626 0.374 0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.626 0.374 0.000
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.626 0.374 0.000
M77.12 Lateral epicondylitis (Upper arm)
0.626 0.374 0.000
M25.8 Other specified joint disorders
0.624 0.375 0.000
M25.71 Osteophyte (Shoulder region)
0.624 0.376 0.000
M71 Other bursopathies
0.623 0.377 0.000
N82.3 Fistula of vagina to large intestine
0.622 0.378 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.621 0.379 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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