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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs62445717
log Bayes Factor = 5.47231
Chromosome 7   position 52,371,416  (GRCh37) Explore rs62445717 on Ensembl!
Variant rs62445717 is part of Cluster X0007

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I30-I52 Other forms of heart disease
1.000 0.000 0.000
I50 Heart failure
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
I50.0 Congestive heart failure
0.997 0.003 0.000
I51 Complications and ill-defined descriptions of heart disease
0.995 0.005 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.992 0.008 0.000
I51.8 Other ill-defined heart diseases
0.985 0.015 0.000
I34 Nonrheumatic mitral valve disorders
0.982 0.018 0.000
I50.1 Left ventricular failure
0.972 0.028 0.000
I34.0 Mitral (valve) insufficiency
0.972 0.028 0.000
# Top node
0.966 0.034 0.000
Chapter XX External causes of morbidity and mortality
0.964 0.036 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.960 0.040 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.952 0.048 0.000
I77 Other disorders of arteries and arterioles
0.945 0.055 0.000
Chapter V Mental and behavioural disorders
0.943 0.057 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.937 0.063 0.000
I27 Other pulmonary heart diseases
0.935 0.065 0.000
I77.1 Stricture of artery
0.926 0.074 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.923 0.077 0.000
Chapter XXII Codes for special purposes
0.922 0.078 0.000
E10-E14 Diabetes mellitus
0.922 0.078 0.000
Y45.0 Opioids and related analgesics
0.917 0.083 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.916 0.084 0.000
E14 Unspecified diabetes mellitus
0.910 0.090 0.000
I27.2 Other secondary pulmonary hypertension
0.910 0.090 0.000
E14.9 Without complications
0.905 0.095 0.000
Chapter VI Diseases of the nervous system
0.899 0.101 0.000
I05-I09 Chronic rheumatic heart diseases
0.899 0.101 0.000
F30-F39 Mood [affective] disorders
0.897 0.103 0.000
I78 Diseases of capillaries
0.889 0.111 0.000
I50.9 Heart failure, unspecified
0.887 0.113 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.880 0.120 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.875 0.125 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.870 0.130 0.000
W00-W19 Falls
0.868 0.132 0.000
I72 Other aneurysm
0.860 0.140 0.000
Q60-Q64 Congenital malformations of the urinary system
0.854 0.146 0.000
I44 Atrioventricular and left bundle-branch block
0.853 0.147 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.842 0.158 0.000
F20 Schizophrenia
0.833 0.167 0.000
U51 Admission status on psychiatric patients
0.831 0.169 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.830 0.170 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.829 0.170 0.000
V20-V29 Motorcycle rider injured in transport accident
0.829 0.171 0.000
E10 Insulin-dependent diabetes mellitus
0.828 0.172 0.000
I78.1 Naevus, nonneoplastic
0.819 0.180 0.000
I31 Other diseases of pericardium
0.817 0.183 0.000
Y43 Primarily systemic agents
0.817 0.183 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.815 0.185 0.000
G20-G26 Extrapyramidal and movement disorders
0.813 0.187 0.000
F31 Bipolar affective disorder
0.811 0.189 0.000
F20.9 Schizophrenia, unspecified
0.810 0.190 0.000
I44.1 Atrioventricular block, second degree
0.810 0.190 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.808 0.192 0.000
I70 Atherosclerosis
0.803 0.197 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.798 0.202 0.000
F33 Recurrent depressive disorder
0.797 0.203 0.000
I30 Acute pericarditis
0.795 0.205 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.795 0.205 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.787 0.213 0.000
I37 Pulmonary valve disorders
0.786 0.214 0.000
Y48 Anaesthetics and therapeutic gases
0.783 0.217 0.000
I51.4 Myocarditis, unspecified
0.781 0.219 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.780 0.220 0.000
I08 Multiple valve diseases
0.779 0.221 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.775 0.225 0.000
W13 Fall from, out of or through building or structure
0.773 0.227 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.772 0.228 0.000
U51.0 Not Previously admitted to a psyciatric hospital
0.772 0.228 0.000
E13 Other specified diabetes mellitus
0.771 0.229 0.000
Q61 Cystic kidney disease
0.771 0.229 0.000
E10.4 With neurological complications
0.770 0.230 0.000
I27.0 Primary pulmonary hypertension
0.770 0.230 0.000
I74 Arterial embolism and thrombosis
0.768 0.232 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.763 0.237 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.760 0.240 0.000
I51.6 Cardiovascular disease, unspecified
0.759 0.241 0.000
Q50-Q56 Congenital malformations of genital organs
0.758 0.242 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.757 0.243 0.000
W20-W49 Exposure to inanimate mechanical forces
0.757 0.243 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.753 0.246 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.747 0.253 0.000
Chapter VIII Diseases of the ear and mastoid process
0.747 0.253 0.000
I07 Rheumatic tricuspid valve diseases
0.741 0.259 0.000
F25 Schizoaffective disorders
0.739 0.261 0.000
Y45.2 Propionic acid derivatives
0.739 0.261 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.735 0.265 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.730 0.270 0.000
W50-W64 Exposure to animate mechanical forces
0.729 0.271 0.000
W75-W84 Other accidental threats to breathing
0.728 0.272 0.000
I72.4 Aneurysm of artery of lower extremity
0.728 0.272 0.000
U80 Agent resistant to penicillin and related antibiotics
0.728 0.272 0.000
V40-V49 Car occupant injured in transport accident
0.727 0.273 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.725 0.275 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.724 0.275 0.000
I35 Nonrheumatic aortic valve disorders
0.723 0.277 0.000
I27.9 Pulmonary heart disease, unspecified
0.722 0.277 0.000
I31.9 Disease of pericardium, unspecified
0.719 0.281 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.719 0.281 0.000
I51.9 Heart disease, unspecified
0.718 0.282 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.718 0.282 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
Q00-Q07 Congenital malformations of the nervous system
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
I72.8 Aneurysm of other specified arteries
0.716 0.284 0.000
Y45.8 Other analgesics and antipyretics
0.714 0.286 0.000
I51.5 Myocardial degeneration
0.714 0.286 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.714 0.286 0.000
G30-G32 Other degenerative diseases of the nervous system
0.713 0.287 0.000
Y52 Agents primarily affecting the cardiovascular system
0.713 0.287 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.710 0.290 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.710 0.290 0.000
F30 Manic episode
0.710 0.290 0.000
G24 Dystonia
0.709 0.290 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.708 0.292 0.000
I49 Other cardiac arrhythmias
0.707 0.292 0.001
G35 Multiple sclerosis
0.707 0.293 0.000
G54 Nerve root and plexus disorders
0.707 0.293 0.000
X20-X29 Contact with venomous animals and plants
0.706 0.294 0.000
W13.9 Unspecified place
0.705 0.295 0.000
Y57 Other and unspecified drugs and medicaments
0.705 0.295 0.000
V28 Motorcycle rider injured in noncollision transport accident
0.705 0.295 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.704 0.296 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.704 0.296 0.000
E11 Non-insulin-dependent diabetes mellitus
0.704 0.296 0.000
Q80-Q89 Other congenital malformations
0.703 0.297 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.700 0.299 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.700 0.300 0.000
Y00-Y09 Assault
0.698 0.302 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.698 0.302 0.000
I95 Hypotension
0.697 0.303 0.000
Y53.1 Other antacids and anti-gastric-secretion drugs
0.695 0.305 0.000
F70-F79 Mental retardation
0.695 0.305 0.000
I51.7 Cardiomegaly
0.695 0.305 0.000
I42 Cardiomyopathy
0.694 0.305 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.693 0.307 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.693 0.307 0.000
U51.1 Previously admitted to a psychiatric hospital of the provider
0.692 0.307 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.692 0.308 0.000
Y45.1 Salicylates
0.691 0.309 0.000
Y35-Y36 Legal intervention and operations of war
0.691 0.309 0.000
Y10-Y34 Event of undetermined intent
0.691 0.309 0.000
X85-X99 Assault
0.691 0.309 0.000
X50-X57 Overexertion, travel and privation
0.691 0.309 0.000
X30-X39 Exposure to forces of nature
0.691 0.309 0.000
X10-X19 Contact with heat and hot substances
0.691 0.309 0.000
X00-X09 Exposure to smoke, fire and flames
0.691 0.309 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.691 0.309 0.000
W65-W74 Accidental drowning and submersion
0.691 0.309 0.000
V98-V99 Other and unspecified transport accidents
0.691 0.309 0.000
V95-V97 Air and space transport accidents
0.691 0.309 0.000
V90-V94 Water transport accidents
0.691 0.309 0.000
V70-V79 Bus occupant injured in transport accident
0.691 0.309 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.691 0.309 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.691 0.309 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.691 0.309 0.000
V01-V09 Pedestrian injured in transport accident
0.691 0.309 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.689 0.311 0.000
Y59 Other and unspecified vaccines and biological substances
0.688 0.312 0.000
Y58 Bacterial vaccines
0.688 0.312 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.688 0.312 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.688 0.312 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.688 0.312 0.000
I44.2 Atrioventricular block, complete
0.688 0.312 0.000
V10-V19 Pedal cyclist injured in transport accident
0.687 0.313 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.687 0.313 0.000
Y95 Nosocomial condition
0.685 0.315 0.000
F34 Persistent mood [affective] disorders
0.684 0.315 0.000
I28 Other diseases of pulmonary vessels
0.682 0.318 0.000
E11.2 With renal complications
0.681 0.319 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.679 0.321 0.000
I77.5 Necrosis of artery
0.677 0.323 0.000
I77.4 Coeliac artery compression syndrome
0.677 0.323 0.000
I77.3 Arterial fibromuscular dysplasia
0.677 0.323 0.000
I77.2 Rupture of artery
0.677 0.323 0.000
I77.0 Arteriovenous fistula, acquired
0.677 0.323 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.677 0.323 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.676 0.324 0.000
I33 Acute and subacute endocarditis
0.672 0.328 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.672 0.328 0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified
0.672 0.328 0.000
Y45.5 4-Aminophenol derivatives
0.672 0.328 0.000
Y45.4 Antirheumatics
0.672 0.328 0.000
G50 Disorders of trigeminal nerve
0.671 0.329 0.000
I27.8 Other specified pulmonary heart diseases
0.670 0.330 0.000
I27.1 Kyphoscoliotic heart disease
0.670 0.330 0.000
I72.0 Aneurysm of carotid artery
0.670 0.330 0.000
I38 Endocarditis, valve unspecified
0.670 0.330 0.000
W06 Fall involving bed
0.670 0.330 0.000
I49.0 Ventricular fibrillation and flutter
0.669 0.330 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.669 0.331 0.000
Q61.0 Congenital single renal cyst
0.668 0.332 0.000
I78.8 Other diseases of capillaries
0.668 0.332 0.000
I77.6 Arteritis, unspecified
0.667 0.333 0.000
G20 Parkinson's disease
0.667 0.333 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.667 0.333 0.000
Y53.4 Other laxatives
0.667 0.333 0.000
Y43.1 Antineoplastic antimetabolites
0.665 0.335 0.000
F10.3 Withdrawal state
0.665 0.335 0.000
F33.9 Recurrent depressive disorder, unspecified
0.665 0.335 0.000
E13.9 Without complications
0.664 0.336 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.662 0.338 0.000
W03.9 Unspecified place
0.661 0.339 0.000
E12 Malnutrition-related diabetes mellitus
0.661 0.339 0.000
H80-H83 Diseases of inner ear
0.661 0.339 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.660 0.340 0.000
W17 Other fall from one level to another
0.658 0.342 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.657 0.343 0.000
Q35-Q37 Cleft lip and cleft palate
0.657 0.343 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.657 0.343 0.000
I09 Other rheumatic heart diseases
0.657 0.343 0.000
I71 Aortic aneurysm and dissection
0.655 0.345 0.000
W10 Fall on and from stairs and steps
0.654 0.346 0.000
E14.8 With unspecified complications
0.653 0.347 0.000
E14.7 With multiple complications
0.653 0.347 0.000
E14.6 With other specified complications
0.653 0.347 0.000
E14.5 With peripheral circulatory complications
0.653 0.347 0.000
E14.4 With neurological complications
0.653 0.347 0.000
E14.2 Withrenal complications
0.653 0.347 0.000
E14.1 With ketoacidosis
0.653 0.347 0.000
E14.0 With coma
0.653 0.347 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.651 0.349 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.650 0.349 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.650 0.350 0.000
N18 Chronic renal failure
0.650 0.350 0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.648 0.352 0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van
0.648 0.352 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.646 0.354 0.000
N18.9 Chronic renal failure, unspecified
0.646 0.354 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.646 0.354 0.000
I51.0 Cardiac septal defect, acquired
0.645 0.355 0.000
I06 Rheumatic aortic valve diseases
0.645 0.355 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.644 0.356 0.000
E20-E35 Disorders of other endocrine glands
0.644 0.356 0.000
F38 Other mood [affective] disorders
0.643 0.357 0.000
F39 Unspecified mood [affective] disorder
0.643 0.357 0.000
E16 Other disorders of pancreatic internal secretion
0.643 0.357 0.000
I05 Rheumatic mitral valve diseases
0.642 0.358 0.000
U80.8 Agent resistant to other penicillin-related antibiotic
0.641 0.359 0.000
E10.2 With renal complications
0.641 0.359 0.000
E10.6 With other specified complications
0.640 0.360 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.640 0.360 0.000
Q63 Other congenital malformations of kidney
0.640 0.360 0.000
N18.3 Chronic kidney disease, stage 3
0.639 0.361 0.000
Y43.4 Immunosuppressive agents
0.639 0.361 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.638 0.362 0.000
I78.9 Disease of capillaries, unspecified
0.637 0.363 0.000
Y48.4 Anaesthetic, unspecified
0.636 0.364 0.000
W19 Unspecified fall
0.636 0.364 0.000
G24.9 Dystonia, unspecified
0.636 0.364 0.000
Q61.2 Polycystic kidney, adult type
0.635 0.365 0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere
0.635 0.365 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.634 0.366 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.634 0.366 0.000
W20 Struck by thrown, projected or falling object
0.633 0.367 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.633 0.367 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.633 0.367 0.000
I37.1 Pulmonary valve insufficiency
0.633 0.367 0.000
I49.4 Other and unspecified premature depolarisation
0.632 0.367 0.000
U81 Agent resistant to vancomycin and related antibiotics
0.631 0.369 0.000
U50 Level of care administered to neonates
0.631 0.369 0.000
U07 Emergency use of U07
0.631 0.369 0.000
U06 Emergency use of U06
0.631 0.369 0.000
U04 Severe acute respiratory syndrome [SARS]
0.631 0.369 0.000
U52 First in a series of a regular day/night admissions
0.631 0.369 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.630 0.370 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.628 0.371 0.000
I34.1 Mitral (valve) prolapse
0.628 0.371 0.000
I07.1 Tricuspid insufficiency
0.628 0.372 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.625 0.375 0.000
I44.6 Other and unspecified fascicular block
0.624 0.376 0.000
F28 Other nonorganic psychotic disorders
0.624 0.376 0.000
F24 Induced delusional disorder
0.624 0.376 0.000
F21 Schizotypal disorder
0.624 0.376 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.622 0.378 0.000
W15 Fall from cliff
0.622 0.378 0.000
W14 Fall from tree
0.622 0.378 0.000
W12 Fall on and from scaffolding
0.622 0.378 0.000
W11 Fall on and from ladder
0.622 0.378 0.000
W09 Fall involving playground equipment
0.622 0.378 0.000
W05 Fall involving wheelchair
0.622 0.378 0.000
W04 Fall while being carried or supported by other persons
0.622 0.378 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.622 0.378 0.000
W00 Fall on same level involving ice and snow
0.622 0.378 0.000
I70.1 Atherosclerosis of renal artery
0.622 0.378 0.000
H65-H75 Diseases of middle ear and mastoid
0.622 0.378 0.000
Y43.3 Other antineoplastic drugs
0.622 0.378 0.000
I35.0 Aortic (valve) stenosis
0.621 0.379 0.000
W21 Striking against or struck by sports equipment
0.619 0.381 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.619 0.381 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.619 0.381 0.000
F11 Mental and behavioural disorders due to use of opioids
0.617 0.382 0.000
G54.0 Brachial plexus disorders
0.617 0.383 0.000
I72.9 Aneurysm of unspecified site
0.616 0.384 0.000
I72.6 Aneurysm and dissection of vertebral artery
0.616 0.384 0.000
I72.5 Aneurysm and dissection of other precerebral arteries
0.616 0.384 0.000
I72.2 Aneurysm of renal artery
0.616 0.384 0.000
I72.1 Aneurysm of artery of upper extremity
0.616 0.384 0.000
I42.9 Cardiomyopathy, unspecified
0.615 0.385 0.000
I30.9 Acute pericarditis, unspecified
0.614 0.385 0.000
Y44 Agents primarily affecting blood constituents
0.614 0.386 0.000
I30.1 Infective pericarditis
0.612 0.388 0.000
Q64 Other congenital malformations of urinary system
0.612 0.388 0.000
W18 Other fall on same level
0.612 0.388 0.000
I44.5 Left posterior fascicular block
0.611 0.389 0.000
I44.4 Left anterior fascicular block
0.611 0.389 0.000
F01 Vascular dementia
0.611 0.389 0.000
F60-F69 Disorders of adult personality and behaviour
0.610 0.390 0.000
Q07 Other congenital malformations of nervous system
0.610 0.390 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.609 0.391 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.609 0.391 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.609 0.391 0.000
E40-E46 Malnutrition
0.609 0.391 0.000
Q89 Other congenital malformations, not elsewhere classified
0.609 0.391 0.000
I70.0 Atherosclerosis of aorta
0.608 0.391 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.608 0.392 0.000
Q54 Hypospadias
0.607 0.393 0.000
E10.5 With peripheral circulatory complications
0.607 0.393 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.606 0.394 0.000
F25.9 Schizoaffective disorder, unspecified
0.605 0.395 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.604 0.396 0.000
O85-O92 Complications predominantly related to the puerperium
0.603 0.397 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.602 0.398 0.000
I85 Oesophageal varices
0.601 0.399 0.000
Chapter I Certain infectious and parasitic diseases
0.599 0.401 0.000
I99 Other and unspecified disorders of circulatory system
0.599 0.401 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.598 0.402 0.000
F20.8 Other schizophrenia
0.597 0.403 0.000
F20.6 Simple schizophrenia
0.597 0.403 0.000
F20.5 Residual schizophrenia
0.597 0.403 0.000
F20.4 Postschizophrenic depression
0.597 0.403 0.000
F20.3 Undifferentiated schizophrenia
0.597 0.403 0.000
F20.2 Catatonic schizophrenia
0.597 0.403 0.000
F20.1 Hebephrenic schizophrenia
0.597 0.403 0.000
I35.1 Aortic (valve) insufficiency
0.597 0.403 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.596 0.404 0.000
U51.2 Previously admitted to a psychiatric hospital of another provider
0.596 0.404 0.000
G52 Disorders of other cranial nerves
0.595 0.405 0.000
G53.0 Postzoster neuralgia
0.595 0.405 0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.595 0.405 0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system
0.595 0.405 0.000
Y53.7 Emetics
0.595 0.405 0.000
Y53.6 Antidiarrhoeal drugs
0.595 0.405 0.000
Y53.5 Digestants
0.595 0.405 0.000
Y53.3 Saline and osmotic laxatives
0.595 0.405 0.000
Y53.2 Stimulant laxatives
0.595 0.405 0.000
Y53.0 Histamine H2-receptor antagonists
0.595 0.405 0.000
G25 Other extrapyramidal and movement disorders
0.595 0.405 0.000
V29 Motorcycle rider injured in other and unspecified transport accidents
0.595 0.405 0.000
V27 Motorcycle rider injured in collision with fixed or stationary object
0.595 0.405 0.000
V26 Motorcycle rider injured in collision with other nonmotor vehicle
0.595 0.405 0.000
V25 Motorcycle rider injured in collision with railway train or railway vehicle
0.595 0.405 0.000
V24 Motorcycle rider injured in collision with heavy transport vehicle or bus
0.595 0.405 0.000
V22 Motorcycle rider injured in collision with two- or three-wheeled motor vehicle
0.595 0.405 0.000
V21 Motorcycle rider injured in collision with pedal cycle
0.595 0.405 0.000
V20 Motorcycle rider injured in collision with pedestrian or animal
0.595 0.405 0.000
E10.8 With unspecified complications
0.594 0.406 0.000
E10.7 With multiple complications
0.594 0.406 0.000
E10.0 With coma
0.594 0.406 0.000
I36 Nonrheumatic tricuspid valve disorders
0.593 0.406 0.000
V28.2 Unspecified motorcycle rider injured in nontraffic accident
0.593 0.407 0.000
I45 Other conduction disorders
0.593 0.407 0.000
G30 Alzheimer's disease
0.592 0.407 0.000
Y48.2 Other and unspecified general anaesthetics
0.592 0.408 0.000
V80-V89 Other land transport accidents
0.592 0.408 0.000
F25.0 Schizoaffective disorder, manic type
0.592 0.408 0.000
E11.5 With peripheral circulatory complications
0.591 0.409 0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]
0.589 0.411 0.000
Y57.5 X-ray contrast media
0.588 0.411 0.000
F99-F99 Unspecified mental disorder
0.588 0.412 0.000
H83 Other diseases of inner ear
0.588 0.412 0.000
I31.8 Other specified diseases of pericardium
0.586 0.414 0.000
I31.2 Haemopericardium, not elsewhere classified
0.586 0.414 0.000
I31.1 Chronic constrictive pericarditis
0.586 0.414 0.000
I31.0 Chronic adhesive pericarditis
0.586 0.414 0.000
Y43.9 Primarily systemic agent, unspecified
0.586 0.414 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.586 0.414 0.000
Y43.6 Enzymes, not elsewhere classified
0.586 0.414 0.000
Y43.5 Acidifying and alkalising agents
0.586 0.414 0.000
Y43.2 Antineoplastic natural products
0.586 0.414 0.000
E14.3 With ophthalmic complications
0.585 0.414 0.000
I78.0 Hereditary haemorrhagic telangiectasia
0.585 0.415 0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.585 0.415 0.000
I79.1 Aortitis in diseases classified elsewhere
0.585 0.415 0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.585 0.415 0.000
W45 Foreign body or object entering through skin
0.585 0.415 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.583 0.416 0.000
G23 Other degenerative diseases of basal ganglia
0.583 0.417 0.000
G21 Secondary Parkinsonism
0.583 0.417 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.583 0.417 0.000
G22 Parkinsonism in diseases classified elsewhere
0.583 0.417 0.000
F80-F89 Disorders of psychological development
0.582 0.418 0.000
F31.8 Other bipolar affective disorders
0.581 0.419 0.000
F31.7 Bipolar affective disorder, currently in remission
0.581 0.419 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.581 0.419 0.000
G51 Facial nerve disorders
0.580 0.420 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.579 0.420 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.579 0.420 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.579 0.420 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.579 0.420 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.579 0.420 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.579 0.421 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.579 0.421 0.000
Y54.3 Benzothiadiazine derivatives
0.579 0.421 0.000
I77.8 Other specified disorders of arteries and arterioles
0.578 0.422 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.577 0.423 0.000
Y43.0 Antiallergic and antiemetic drugs
0.576 0.423 0.000
I95.1 Orthostatic hypotension
0.576 0.424 0.000
I70.9 Generalised and unspecified atherosclerosis
0.575 0.424 0.000
I70.8 Atherosclerosis of other arteries
0.575 0.424 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.575 0.425 0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.574 0.425 0.000
I89.1 Lymphangitis
0.572 0.427 0.000
F33.8 Other recurrent depressive disorders
0.572 0.428 0.000
F33.4 Recurrent depressive disorder, currently in remission
0.572 0.428 0.000
F33.0 Recurrent depressive disorder, current episode mild
0.572 0.428 0.000
N18.0 End-stage renal disease
0.572 0.428 0.000
U89 Agent resistant to other and unspecified antibiotics
0.570 0.429 0.000
I30.8 Other forms of acute pericarditis
0.570 0.430 0.000
I30.0 Acute nonspecific idiopathic pericarditis
0.570 0.430 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.570 0.430 0.000
Y98 Lifestyle-related condition
0.570 0.430 0.000
Y97 Environmental-pollution-related condition
0.570 0.430 0.000
Y96 Work-related condition
0.570 0.430 0.000
G55.0 Nerve root and plexus compressions in neoplastic disease
0.569 0.430 0.000
W57 Bitten or stung by non-venomous insect and other non-venomous arthropods
0.569 0.431 0.000
G82 Paraplegia and tetraplegia
0.568 0.431 0.000
Q61.3 Polycystic kidney, unspecified
0.568 0.432 0.000
I08.8 Other multiple valve diseases
0.567 0.433 0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.567 0.433 0.000
N18.4 Chronic kidney disease, stage 4
0.566 0.434 0.000
G00 Bacterial meningitis, not elsewhere classified
0.566 0.434 0.000
E65-E68 Obesity and other hyperalimentation
0.565 0.434 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.564 0.436 0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.564 0.436 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.564 0.436 0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.564 0.436 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.564 0.436 0.000
G54.4 Lumbosacral root disorders, not elsewhere classified
0.564 0.436 0.000
F02 Dementia in other diseases classified elsewhere
0.564 0.436 0.000
I37.9 Pulmonary valve disorder, unspecified
0.564 0.436 0.000
I37.8 Other pulmonary valve disorders
0.564 0.436 0.000
I37.2 Pulmonary valve stenosis with insufficiency
0.564 0.436 0.000
I37.0 Pulmonary valve stenosis
0.564 0.436 0.000
I44.3 Other and unspecified atrioventricular block
0.563 0.437 0.000
F10.4 Withdrawal state with delirium
0.563 0.437 0.000
Q14 Congenital malformations of posterior segment of eye
0.562 0.438 0.000
Y49.2 Other and unspecified antidepressants
0.562 0.438 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.562 0.438 0.000
Y48.5 Therapeutic gases
0.561 0.438 0.000
Y48.3 Local anaesthetics
0.561 0.438 0.000
Y48.1 Parenteral anaesthetics
0.561 0.438 0.000
Y48.0 Inhaled anaesthetics
0.561 0.438 0.000
F22 Persistent delusional disorders
0.561 0.439 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.560 0.440 0.000
W84 Unspecified threat to breathing
0.559 0.440 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.559 0.441 0.000
X48 Accidental poisoning by and exposure to pesticides
0.559 0.441 0.000
X47 Accidental poisoning by and exposure to other gases and vapours
0.559 0.441 0.000
X46 Accidental poisoning by and exposure to organic solvents and halogenated hydrocarbons and their vapours
0.559 0.441 0.000
X45 Accidental poisoning by and exposure to alcohol
0.559 0.441 0.000
X44 Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
0.559 0.441 0.000
X43 Accidental poisoning by and exposure to other drugs acting on the autonomic nervous system
0.559 0.441 0.000
X42 Accidental poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.559 0.441 0.000
X40 Accidental poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics
0.559 0.441 0.000
Y54.5 Other diuretics
0.559 0.441 0.000
W19.4 Street and highway
0.559 0.441 0.000
I08.9 Multiple valve disease, unspecified
0.558 0.441 0.000
F20.0 Paranoid schizophrenia
0.558 0.442 0.000
I87 Other disorders of veins
0.558 0.442 0.000
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances
0.558 0.442 0.000
W08 Fall involving other furniture
0.557 0.443 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.555 0.445 0.000
I81 Portal vein thrombosis
0.555 0.445 0.000
F30.9 Manic episode, unspecified
0.554 0.445 0.000
W13.8 Other specified place
0.554 0.445 0.000
W13.0 Home
0.554 0.445 0.000
W13.7 Farm
0.554 0.445 0.000
W13.6 Industrial and construction area
0.554 0.445 0.000
W13.5 Trade and service area
0.554 0.445 0.000
W13.4 Street and highway
0.554 0.445 0.000
W13.3 Sports and athletics area
0.554 0.445 0.000
W13.2 School, other institution and public administrative area
0.554 0.445 0.000
W13.1 Residential institution
0.554 0.445 0.000
X41.9 Unspecified place
0.554 0.446 0.000
Q60.0 Renal agenesis, unilateral
0.554 0.446 0.000
Q53 Undescended testicle
0.554 0.446 0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system
0.554 0.446 0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified
0.554 0.446 0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified
0.554 0.446 0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.554 0.446 0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.554 0.446 0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified
0.554 0.446 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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