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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs60164086
log Bayes Factor = 8.49074
Chromosome 19   position 19,300,192  (GRCh37) Explore rs60164086 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter VIII Diseases of the ear and mastoid process
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
1.000 0.000 0.000
G40-G47 Episodic and paroxysmal disorders
0.999 0.001 0.000
G47 Sleep disorders
0.998 0.002 0.000
H65-H75 Diseases of middle ear and mastoid
0.998 0.002 0.000
G47.9 Sleep disorder, unspecified
0.997 0.003 0.000
E10-E14 Diabetes mellitus
0.997 0.003 0.000
E20-E35 Disorders of other endocrine glands
0.994 0.006 0.000
H90-H95 Other disorders of ear
0.991 0.009 0.000
E10 Insulin-dependent diabetes mellitus
0.991 0.009 0.000
H65 Nonsuppurative otitis media
0.985 0.015 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.985 0.015 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.982 0.018 0.000
B35-B49 Mycoses
0.977 0.023 0.000
H65.3 Chronic mucoid otitis media
0.974 0.026 0.000
A00-A09 Intestinal infectious diseases
0.974 0.026 0.000
B07 Viral warts
0.973 0.027 0.000
A04 Other bacterial intestinal infections
0.970 0.030 0.000
Chapter IX Diseases of the circulatory system
0.967 0.033 0.000
I05-I09 Chronic rheumatic heart diseases
0.964 0.036 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.963 0.037 0.000
B37 Candidiasis
0.959 0.041 0.000
I08 Multiple valve diseases
0.955 0.045 0.000
E10.3 With ophthalmic complications
0.954 0.046 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.954 0.046 0.000
H80-H83 Diseases of inner ear
0.947 0.053 0.000
H92 Otalgia and effusion of ear
0.944 0.056 0.000
A04.5 Campylobacter enteritis
0.935 0.065 0.000
E10.9 Without complications
0.932 0.068 0.000
E21.0 Primary hyperparathyroidism
0.932 0.068 0.000
E27 Other disorders of adrenal gland
0.932 0.068 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.931 0.069 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.931 0.069 0.000
A04.7 Enterocolitis due to Clostridium difficile
0.930 0.070 0.000
H92.0 Otalgia
0.923 0.077 0.000
I08.0 Disorders of both mitral and aortic valves
0.918 0.082 0.000
H90 Conductive and sensorineural hearing loss
0.917 0.083 0.000
E21.3 Hyperparathyroidism, unspecified
0.914 0.086 0.000
G47.3 Sleep apnoea
0.905 0.095 0.000
G35 Multiple sclerosis
0.904 0.096 0.000
E00-E07 Disorders of thyroid gland
0.899 0.101 0.000
B37.0 Candidal stomatitis
0.898 0.102 0.000
H81 Disorders of vestibular function
0.895 0.105 0.000
H66 Suppurative and unspecified otitis media
0.895 0.105 0.000
I05 Rheumatic mitral valve diseases
0.893 0.107 0.000
G50 Disorders of trigeminal nerve
0.892 0.108 0.000
G51 Facial nerve disorders
0.891 0.109 0.000
E11 Non-insulin-dependent diabetes mellitus
0.889 0.111 0.000
B37.3 Candidiasis of vulva and vagina
0.883 0.117 0.000
E10.2 With renal complications
0.881 0.119 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.879 0.121 0.000
H72 Perforation of tympanic membrane
0.876 0.124 0.000
E70-E90 Metabolic disorders
0.867 0.133 0.000
H93 Other disorders of ear, not elsewhere classified
0.864 0.136 0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
0.853 0.147 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.853 0.147 0.000
H71 Cholesteatoma of middle ear
0.849 0.151 0.000
B37.8 Candidiasis of other sites
0.847 0.153 0.000
B25-B34 Other viral diseases
0.844 0.156 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.844 0.156 0.000
G57 Mononeuropathies of lower limb
0.837 0.163 0.000
G43 Migraine
0.831 0.169 0.000
G50.0 Trigeminal neuralgia
0.829 0.171 0.000
I71 Aortic aneurysm and dissection
0.825 0.175 0.000
Q50-Q56 Congenital malformations of genital organs
0.825 0.175 0.000
G40 Epilepsy
0.824 0.176 0.000
G51.0 Bell's palsy
0.820 0.180 0.000
H81.1 Benign paroxysmal vertigo
0.820 0.180 0.000
A04.8 Other specified bacterial intestinal infections
0.812 0.188 0.000
E11.3 With ophthalmic complications
0.810 0.190 0.000
I08.8 Other multiple valve diseases
0.809 0.191 0.000
G70-G73 Diseases of myoneural junction and muscle
0.809 0.191 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.805 0.195 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.804 0.196 0.000
Q80-Q89 Other congenital malformations
0.803 0.197 0.000
H83 Other diseases of inner ear
0.802 0.198 0.000
E05.9 Thyrotoxicosis, unspecified
0.801 0.199 0.000
B35 Dermatophytosis
0.796 0.204 0.000
B15-B19 Viral hepatitis
0.793 0.207 0.000
H72.0 Central perforation of tympanic membrane
0.792 0.208 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.788 0.212 0.000
H65.9 Nonsuppurative otitis media, unspecified
0.783 0.217 0.000
Chapter XX External causes of morbidity and mortality
0.781 0.219 0.000
E27.9 Disorder of adrenal gland, unspecified
0.781 0.219 0.000
I05.0 Mitral stenosis
0.777 0.223 0.000
G37 Other demyelinating diseases of central nervous system
0.776 0.224 0.000
H73 Other disorders of tympanic membrane
0.774 0.226 0.000
H60-H62 Diseases of external ear
0.771 0.229 0.000
B00 Herpesviral [herpes simplex] infections
0.771 0.229 0.000
E27.2 Addisonian crisis
0.770 0.230 0.000
H66.9 Otitis media, unspecified
0.768 0.232 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.767 0.233 0.000
E11.8 With unspecified complications
0.767 0.233 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.766 0.234 0.000
E11.1 With ketoacidosis
0.766 0.234 0.000
H81.0 Meniere's disease
0.763 0.237 0.000
E34 Other endocrine disorders
0.762 0.238 0.000
Chapter XXII Codes for special purposes
0.761 0.238 0.000
I09 Other rheumatic heart diseases
0.759 0.241 0.000
E27.1 Primary adrenocortical insufficiency
0.758 0.242 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.756 0.244 0.000
E86 Volume depletion
0.755 0.245 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.755 0.245 0.000
E10.5 With peripheral circulatory complications
0.752 0.248 0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral
0.752 0.248 0.000
H66.3 Other chronic suppurative otitis media
0.748 0.252 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.745 0.255 0.000
E06 Thyroiditis
0.743 0.257 0.000
I60-I69 Cerebrovascular diseases
0.739 0.261 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.736 0.264 0.000
E10.8 With unspecified complications
0.736 0.264 0.000
H93.1 Tinnitus
0.735 0.265 0.000
I05.1 Rheumatic mitral insufficiency
0.734 0.266 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.733 0.267 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.732 0.268 0.000
Q82 Other congenital malformations of skin
0.726 0.274 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.726 0.274 0.000
E50-E64 Other nutritional deficiencies
0.725 0.274 0.000
B25 Cytomegaloviral disease
0.724 0.276 0.000
E28 Ovarian dysfunction
0.721 0.278 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.719 0.281 0.000
G00 Bacterial meningitis, not elsewhere classified
0.718 0.282 0.000
H72.1 Attic perforation of tympanic membrane
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.717 0.283 0.000
B50-B64 Protozoal diseases
0.717 0.283 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.717 0.283 0.000
A75-A79 Rickettsioses
0.717 0.283 0.000
A70-A74 Other diseases caused by chlamydiae
0.717 0.283 0.000
A65-A69 Other spirochaetal diseases
0.717 0.283 0.000
A20-A28 Certain zoonotic bacterial diseases
0.717 0.283 0.000
A15-A19 Tuberculosis
0.717 0.283 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.716 0.284 0.000
G47.4 Narcolepsy and cataplexy
0.716 0.284 0.000
G47.2 Disorders of the sleep-wake schedule
0.716 0.284 0.000
A30-A49 Other bacterial diseases
0.716 0.284 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.715 0.284 0.000
H68 Eustachian salpingitis and obstruction
0.715 0.284 0.000
H67 Otitis media in diseases classified elsewhere
0.715 0.284 0.000
H65.4 Other chronic nonsuppurative otitis media
0.715 0.285 0.000
E12 Malnutrition-related diabetes mellitus
0.714 0.285 0.000
G57.6 Lesion of plantar nerve
0.713 0.287 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.712 0.288 0.000
E32 Diseases of thymus
0.712 0.288 0.000
E31 Polyglandular dysfunction
0.712 0.288 0.000
E30 Disorders of puberty, not elsewhere classified
0.712 0.288 0.000
E26 Hyperaldosteronism
0.712 0.288 0.000
E25 Adrenogenital disorders
0.712 0.288 0.000
G47.8 Other sleep disorders
0.712 0.288 0.000
E14 Unspecified diabetes mellitus
0.712 0.288 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.711 0.289 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.711 0.289 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.710 0.290 0.000
E10.7 With multiple complications
0.710 0.290 0.000
E10.6 With other specified complications
0.710 0.290 0.000
E10.0 With coma
0.710 0.290 0.000
E20 Hypoparathyroidism
0.708 0.292 0.000
G90-G99 Other disorders of the nervous system
0.707 0.293 0.000
H65.1 Other acute nonsuppurative otitis media
0.706 0.294 0.000
H65.0 Acute serous otitis media
0.706 0.294 0.000
B06 Rubella [German measles]
0.706 0.294 0.000
B05 Measles
0.706 0.294 0.000
B01 Varicella [chickenpox]
0.706 0.294 0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions
0.706 0.294 0.000
B04 Monkeypox
0.706 0.294 0.000
B03 Smallpox
0.706 0.294 0.000
E11.6 With other specified complications
0.706 0.294 0.000
G43.9 Migraine, unspecified
0.705 0.295 0.000
G54 Nerve root and plexus disorders
0.704 0.296 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.704 0.296 0.000
E21.4 Other specified disorders of parathyroid gland
0.704 0.296 0.000
E21.2 Other hyperparathyroidism
0.704 0.296 0.000
E27.8 Other specified disorders of adrenal gland
0.703 0.297 0.000
H70 Mastoiditis and related conditions
0.701 0.299 0.000
G51.8 Other disorders of facial nerve
0.700 0.299 0.000
B48 Other mycoses, not elsewhere classified
0.700 0.300 0.000
B47 Mycetoma
0.700 0.300 0.000
B46 Zygomycosis
0.700 0.300 0.000
B45 Cryptococcosis
0.700 0.300 0.000
B43 Chromomycosis and phaeomycotic abscess
0.700 0.300 0.000
B42 Sporotrichosis
0.700 0.300 0.000
B41 Paracoccidioidomycosis
0.700 0.300 0.000
B40 Blastomycosis
0.700 0.300 0.000
B39 Histoplasmosis
0.700 0.300 0.000
B38 Coccidioidomycosis
0.700 0.300 0.000
B36 Other superficial mycoses
0.700 0.300 0.000
E13 Other specified diabetes mellitus
0.699 0.301 0.000
A07 Other protozoal intestinal diseases
0.698 0.302 0.000
A06 Amoebiasis
0.698 0.302 0.000
A05 Other bacterial foodborne intoxications
0.698 0.302 0.000
A03 Shigellosis
0.698 0.302 0.000
A01 Typhoid and paratyphoid fevers
0.698 0.302 0.000
A00 Cholera
0.698 0.302 0.000
H83.0 Labyrinthitis
0.698 0.302 0.000
I95 Hypotension
0.698 0.302 0.000
H69 Other disorders of Eustachian tube
0.697 0.303 0.000
A04.9 Bacterial intestinal infection, unspecified
0.696 0.304 0.000
A04.6 Enteritis due to Yersinia enterocolitica
0.696 0.304 0.000
A04.4 Other intestinal Escherichia coli infections
0.696 0.304 0.000
A04.3 Enterohaemorrhagic Escherichia coli infection
0.696 0.304 0.000
A04.2 Enteroinvasive Escherichia coli infection
0.696 0.304 0.000
A04.1 Enterotoxigenic Escherichia coli infection
0.696 0.304 0.000
A04.0 Enteropathogenic Escherichia coli infection
0.696 0.304 0.000
I00-I02 Acute rheumatic fever
0.693 0.307 0.000
I78 Diseases of capillaries
0.693 0.307 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.692 0.307 0.000
G50.1 Atypical facial pain
0.692 0.308 0.000
I06 Rheumatic aortic valve diseases
0.691 0.309 0.000
G58 Other mononeuropathies
0.691 0.309 0.000
H93.9 Disorder of ear, unspecified
0.691 0.309 0.000
E23 Hypofunction and other disorders of pituitary gland
0.690 0.310 0.000
G52 Disorders of other cranial nerves
0.690 0.310 0.000
E87.7 Fluid overload
0.689 0.311 0.000
B37.7 Candidal septicaemia
0.688 0.312 0.000
B37.6 Candidal endocarditis
0.688 0.312 0.000
B37.5 Candidal meningitis
0.688 0.312 0.000
B37.4 Candidiasis of other urogenital sites
0.688 0.312 0.000
B37.2 Candidiasis of skin and nail
0.688 0.312 0.000
B37.1 Pulmonary candidiasis
0.688 0.312 0.000
G71 Primary disorders of muscles
0.685 0.315 0.000
I05.9 Mitral valve disease, unspecified
0.685 0.315 0.000
I08.9 Multiple valve disease, unspecified
0.685 0.315 0.000
B02 Zoster [herpes zoster]
0.684 0.316 0.000
G36 Other acute disseminated demyelination
0.684 0.316 0.000
B35.3 Tinea pedis
0.682 0.318 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.682 0.318 0.000
A80-A89 Viral infections of the central nervous system
0.681 0.319 0.000
H82 Vertiginous syndromes in diseases classified elsewhere
0.679 0.321 0.000
I05.2 Mitral stenosis with insufficiency
0.678 0.322 0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.677 0.323 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.677 0.323 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.677 0.323 0.000
H92.2 Otorrhagia
0.676 0.323 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.676 0.323 0.000
I62 Other nontraumatic intracranial haemorrhage
0.676 0.324 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.675 0.325 0.000
I77 Other disorders of arteries and arterioles
0.674 0.326 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.674 0.326 0.000
I63 Cerebral infarction
0.673 0.327 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.673 0.327 0.000
B49 Unspecified mycosis
0.672 0.328 0.000
E29 Testicular dysfunction
0.670 0.330 0.000
B99-B99 Other infectious diseases
0.669 0.331 0.000
E04 Other non-toxic goitre
0.668 0.332 0.000
E27.5 Adrenomedullary hyperfunction
0.668 0.332 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.668 0.332 0.000
E27.0 Other adrenocortical overactivity
0.668 0.332 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.668 0.332 0.000
Q35-Q37 Cleft lip and cleft palate
0.668 0.332 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.668 0.332 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.666 0.334 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.664 0.336 0.000
G57.5 Tarsal tunnel syndrome
0.663 0.337 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.659 0.341 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.658 0.342 0.000
Q60-Q64 Congenital malformations of the urinary system
0.658 0.342 0.000
Q82.8 Other specified congenital malformations of skin
0.658 0.342 0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.657 0.343 0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.657 0.343 0.000
H90.0 Conductive hearing loss, bilateral
0.657 0.343 0.000
H65.2 Chronic serous otitis media
0.656 0.344 0.000
H90.5 Sensorineural hearing loss, unspecified
0.655 0.344 0.000
E24 Cushing's syndrome
0.654 0.346 0.000
H81.2 Vestibular neuronitis
0.654 0.346 0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified
0.654 0.346 0.000
G41 Status epilepticus
0.653 0.347 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.652 0.348 0.000
E73 Lactose intolerance
0.652 0.348 0.000
D80-D89 Certain disorders involving the immune mechanism
0.651 0.349 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.650 0.350 0.000
G51.9 Disorder of facial nerve, unspecified
0.650 0.350 0.000
B65-B83 Helminthiases
0.648 0.352 0.000
E85 Amyloidosis
0.646 0.354 0.000
G93 Other disorders of brain
0.645 0.355 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.644 0.356 0.000
E00 Congenital iodine-deficiency syndrome
0.644 0.356 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.644 0.356 0.000
E87.5 Hyperkalaemia
0.644 0.356 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.644 0.356 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.644 0.356 0.000
Q50.4 Embryonic cyst of Fallopian tube
0.644 0.356 0.000
E40-E46 Malnutrition
0.642 0.357 0.000
H81.9 Disorder of vestibular function, unspecified
0.642 0.358 0.000
H81.8 Other disorders of vestibular function
0.642 0.358 0.000
H81.4 Vertigo of central origin
0.642 0.358 0.000
H81.3 Other peripheral vertigo
0.642 0.358 0.000
H66.4 Suppurative otitis media, unspecified
0.642 0.358 0.000
H66.2 Chronic atticoantral suppurative otitis media
0.642 0.358 0.000
H66.1 Chronic tubotympanic suppurative otitis media
0.642 0.358 0.000
H66.0 Acute suppurative otitis media
0.642 0.358 0.000
I95.9 Hypotension, unspecified
0.642 0.358 0.000
Q51 Congenital malformations of uterus and cervix
0.641 0.359 0.000
I05.8 Other mitral valve diseases
0.640 0.360 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.640 0.360 0.000
G50.9 Disorder of trigeminal nerve, unspecified
0.640 0.360 0.000
G50.8 Other disorders of trigeminal nerve
0.640 0.360 0.000
B18 Chronic viral hepatitis
0.639 0.361 0.000
G51.4 Facial myokymia
0.639 0.361 0.000
G51.3 Clonic hemifacial spasm
0.639 0.361 0.000
G51.2 Melkersson's syndrome
0.639 0.361 0.000
G51.1 Geniculate ganglionitis
0.639 0.361 0.000
E11.7 With multiple complications
0.637 0.362 0.000
B25.9 Cytomegaloviral disease, unspecified
0.638 0.362 0.000
Q53 Undescended testicle
0.635 0.365 0.000
A41 Other septicaemia
0.635 0.365 0.000
A02 Other Salmonella infections
0.632 0.368 0.000
E06.3 Autoimmune thyroiditis
0.631 0.369 0.000
I27 Other pulmonary heart diseases
0.630 0.370 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.630 0.370 0.000
G03 Meningitis due to other and unspecified causes
0.630 0.370 0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.630 0.370 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.630 0.370 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.630 0.370 0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.630 0.370 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.630 0.370 0.000
H90.3 Sensorineural hearing loss, bilateral
0.629 0.370 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.629 0.371 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.628 0.372 0.000
G56 Mononeuropathies of upper limb
0.628 0.372 0.000
H72.2 Other marginal perforations of tympanic membrane
0.628 0.372 0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified
0.627 0.373 0.000
Y43 Primarily systemic agents
0.626 0.373 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.624 0.376 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.624 0.376 0.000
G43.1 Migraine with aura [classical migraine]
0.624 0.376 0.000
B34 Viral infection of unspecified site
0.623 0.377 0.000
E84 Cystic fibrosis
0.622 0.378 0.000
E79 Disorders of purine and pyrimidine metabolism
0.622 0.378 0.000
E77 Disorders of glycoprotein metabolism
0.622 0.378 0.000
E76 Disorders of glycosaminoglycan metabolism
0.622 0.378 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.622 0.378 0.000
E72 Other disorders of amino-acid metabolism
0.622 0.378 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.622 0.378 0.000
E70 Disorders of aromatic amino-acid metabolism
0.622 0.378 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.622 0.378 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.622 0.378 0.000
V20-V29 Motorcycle rider injured in transport accident
0.620 0.380 0.000
E10.4 With neurological complications
0.620 0.380 0.000
H93.8 Other specified disorders of ear
0.619 0.381 0.000
H93.3 Disorders of acoustic nerve
0.619 0.381 0.000
H93.2 Other abnormal auditory perceptions
0.619 0.381 0.000
H93.0 Degenerative and vascular disorders of ear
0.619 0.381 0.000
Y40 Systemic antibiotics
0.619 0.381 0.000
I07 Rheumatic tricuspid valve diseases
0.618 0.381 0.000
B00.9 Herpesviral infection, unspecified
0.618 0.382 0.000
E53 Deficiency of other B group vitamins
0.618 0.382 0.000
B44 Aspergillosis
0.617 0.382 0.000
B95-B98 Bacterial, viral and other infectious agents
0.617 0.383 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.616 0.384 0.000
G44 Other headache syndromes
0.616 0.384 0.000
H90.2 Conductive hearing loss, unspecified
0.615 0.385 0.000
E11.0 With coma
0.614 0.386 0.000
E74 Other disorders of carbohydrate metabolism
0.613 0.387 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.613 0.387 0.000
H73.8 Other specified disorders of tympanic membrane
0.613 0.387 0.000
I09.9 Rheumatic heart disease, unspecified
0.613 0.387 0.000
Q00-Q07 Congenital malformations of the nervous system
0.612 0.387 0.000
H61 Other disorders of external ear
0.610 0.390 0.000
D68 Other coagulation defects
0.610 0.390 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.608 0.391 0.000
G40.8 Other epilepsy
0.608 0.392 0.000
Q39 Congenital malformations of oesophagus
0.607 0.393 0.000
E14.1 With ketoacidosis
0.606 0.394 0.000
B33 Other viral diseases, not elsewhere classified
0.605 0.395 0.000
B30 Viral conjunctivitis
0.605 0.395 0.000
B27 Infectious mononucleosis
0.605 0.395 0.000
B26 Mumps
0.605 0.395 0.000
E05.8 Other thyrotoxicosis
0.605 0.395 0.000
E05.5 Thyroid crisis or storm
0.605 0.395 0.000
E05.4 Thyrotoxicosis factitia
0.605 0.395 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.605 0.395 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.605 0.395 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.605 0.395 0.000
X10-X19 Contact with heat and hot substances
0.605 0.395 0.000
H95.1 Other disorders following mastoidectomy
0.604 0.396 0.000
E10.1 With ketoacidosis
0.604 0.396 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.604 0.396 0.000
G00.1 Pneumococcal meningitis
0.603 0.397 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.602 0.398 0.000
G57.8 Other mononeuropathies of lower limb
0.602 0.398 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.601 0.399 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.601 0.399 0.000
G71.0 Muscular dystrophy
0.601 0.399 0.000
G57.9 Mononeuropathy of lower limb, unspecified
0.600 0.400 0.000
G57.4 Lesion of medial popliteal nerve
0.600 0.400 0.000
G57.3 Lesion of lateral popliteal nerve
0.600 0.400 0.000
G57.2 Lesion of femoral nerve
0.600 0.400 0.000
G57.0 Lesion of sciatic nerve
0.600 0.400 0.000
G57.1 Meralgia paraesthetica
0.599 0.401 0.000
E07 Other disorders of thyroid
0.597 0.403 0.000
E88 Other metabolic disorders
0.596 0.404 0.000
E34.9 Endocrine disorder, unspecified
0.596 0.404 0.000
G43.3 Complicated migraine
0.595 0.404 0.000
G43.2 Status migrainosus
0.595 0.404 0.000
G43.0 Migraine without aura [common migraine]
0.595 0.404 0.000
X20-X29 Contact with venomous animals and plants
0.594 0.406 0.000
X50-X57 Overexertion, travel and privation
0.593 0.407 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.592 0.408 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.592 0.408 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.592 0.408 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.592 0.408 0.000
Q56 Indeterminate sex and pseudohermaphroditism
0.592 0.408 0.000
Q55 Other congenital malformations of male genital organs
0.592 0.408 0.000
Q52 Other congenital malformations of female genitalia
0.592 0.408 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.591 0.409 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.591 0.409 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.590 0.410 0.000
Chapter VII Diseases of the eye and adnexa
0.588 0.412 0.000
W50-W64 Exposure to animate mechanical forces
0.585 0.414 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.585 0.415 0.000
H80 Otosclerosis
0.584 0.416 0.000
E28.3 Primary ovarian failure
0.584 0.416 0.000
G70 Myasthenia gravis and other myoneural disorders
0.584 0.416 0.000
E22 Hyperfunction of pituitary gland
0.584 0.416 0.000
E87.0 Hyperosmolality and hypernatraemia
0.583 0.416 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.583 0.417 0.000
I77.6 Arteritis, unspecified
0.583 0.417 0.000
B17 Other acute viral hepatitis
0.582 0.418 0.000
H91 Other hearing loss
0.582 0.418 0.000
G40.5 Special epileptic syndromes
0.580 0.420 0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.580 0.420 0.000
Q89 Other congenital malformations, not elsewhere classified
0.580 0.420 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.578 0.422 0.000
V10-V19 Pedal cyclist injured in transport accident
0.577 0.423 0.000
V80-V89 Other land transport accidents
0.577 0.423 0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems
0.576 0.424 0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified
0.576 0.424 0.000
Q84 Other congenital malformations of integument
0.576 0.424 0.000
Q83 Congenital malformations of breast
0.576 0.424 0.000
Q81 Epidermolysis bullosa
0.576 0.424 0.000
Q80 Congenital ichthyosis
0.576 0.424 0.000
D55-D59 Haemolytic anaemias
0.576 0.424 0.000
G30-G32 Other degenerative diseases of the nervous system
0.575 0.425 0.000
D68.2 Hereditary deficiency of other clotting factors
0.575 0.425 0.000
H83.9 Disease of inner ear, unspecified
0.575 0.425 0.000
H83.8 Other specified diseases of inner ear
0.575 0.425 0.000
H83.3 Noise effects on inner ear
0.575 0.425 0.000
H83.2 Labyrinthine dysfunction
0.575 0.425 0.000
H83.1 Labyrinthine fistula
0.575 0.425 0.000
I61 Intracerebral haemorrhage
0.575 0.425 0.000
G43.8 Other migraine
0.574 0.425 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.574 0.426 0.000
I95.0 Idiopathic hypotension
0.572 0.428 0.000
B16 Acute hepatitis B
0.571 0.428 0.000
I74 Arterial embolism and thrombosis
0.571 0.429 0.000
E83 Disorders of mineral metabolism
0.571 0.429 0.000
B35.9 Dermatophytosis, unspecified
0.571 0.429 0.000
B35.8 Other dermatophytoses
0.571 0.429 0.000
B35.6 Tinea cruris
0.571 0.429 0.000
B35.5 Tinea imbricata
0.571 0.429 0.000
B35.4 Tinea corporis
0.571 0.429 0.000
B35.2 Tinea manuum
0.571 0.429 0.000
B35.0 Tinea barbae and tinea capitis
0.571 0.429 0.000
I63.9 Cerebral infarction, unspecified
0.570 0.430 0.000
Y00-Y09 Assault
0.570 0.430 0.000
B19 Unspecified viral hepatitis
0.568 0.432 0.000
I78.1 Naevus, nonneoplastic
0.568 0.432 0.000
Q54 Hypospadias
0.564 0.436 0.000
Chapter V Mental and behavioural disorders
0.564 0.436 0.000
Y44 Agents primarily affecting blood constituents
0.563 0.437 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.563 0.437 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.562 0.438 0.000
Y35-Y36 Legal intervention and operations of war
0.560 0.440 0.000
Y10-Y34 Event of undetermined intent
0.560 0.440 0.000
X85-X99 Assault
0.560 0.440 0.000
X30-X39 Exposure to forces of nature
0.560 0.440 0.000
X00-X09 Exposure to smoke, fire and flames
0.560 0.440 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.560 0.440 0.000
W75-W84 Other accidental threats to breathing
0.560 0.440 0.000
W65-W74 Accidental drowning and submersion
0.560 0.440 0.000
V98-V99 Other and unspecified transport accidents
0.560 0.440 0.000
V95-V97 Air and space transport accidents
0.560 0.440 0.000
V90-V94 Water transport accidents
0.560 0.440 0.000
V70-V79 Bus occupant injured in transport accident
0.560 0.440 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.560 0.440 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.560 0.440 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.560 0.440 0.000
V01-V09 Pedestrian injured in transport accident
0.560 0.440 0.000
H55-H59 Other disorders of eye and adnexa
0.560 0.440 0.000
E11.2 With renal complications
0.560 0.440 0.000
Q82.5 Congenital nonneoplastic naevus
0.559 0.441 0.000
E65-E68 Obesity and other hyperalimentation
0.558 0.441 0.000
E78.0 Pure hypercholesterolaemia
0.558 0.442 0.000
D86 Sarcoidosis
0.558 0.442 0.000
V40-V49 Car occupant injured in transport accident
0.558 0.442 0.000
B15 Acute hepatitis A
0.558 0.442 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.558 0.442 0.000
I27.2 Other secondary pulmonary hypertension
0.557 0.443 0.000
I95.8 Other hypotension
0.557 0.443 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.557 0.443 0.000
G37.8 Other specified demyelinating diseases of central nervous system
0.557 0.443 0.000
G37.5 Concentric sclerosis [Balo]
0.557 0.443 0.000
G37.4 Subacute necrotising myelitis
0.557 0.443 0.000
G37.2 Central pontine myelinolysis
0.557 0.443 0.000
G37.1 Central demyelination of corpus callosum
0.557 0.443 0.000
G37.0 Diffuse sclerosis
0.557 0.443 0.000
G56.2 Lesion of ulnar nerve
0.555 0.445 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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