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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs200876443
log Bayes Factor = 17.0144
Chromosome 19   position 50,363,585  (GRCh37) Explore rs200876443 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
N80-N98 Noninflammatory disorders of female genital tract
1.000 0.000 0.000
G40-G47 Episodic and paroxysmal disorders
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
Chapter XIV Diseases of the genitourinary system
0.999 0.001 0.000
G40 Epilepsy
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
Chapter X Diseases of the respiratory system
0.997 0.003 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.996 0.004 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.995 0.005 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.992 0.008 0.000
I84 Haemorrhoids
0.991 0.009 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.988 0.012 0.000
M20-M25 Other joint disorders
0.985 0.015 0.000
N87 Dysplasia of cervix uteri
0.982 0.018 0.000
I84.2 Internal haemorrhoids without complication
0.978 0.022 0.000
G40.9 Epilepsy, unspecified
0.978 0.022 0.000
I10-I15 Hypertensive diseases
0.977 0.023 0.000
N83.2 Other and unspecified ovarian cysts
0.974 0.026 0.000
D60-D64 Aplastic and other anaemias
0.971 0.029 0.000
J00-J06 Acute upper respiratory infections
0.968 0.032 0.000
Chapter VIII Diseases of the ear and mastoid process
0.963 0.037 0.000
G90-G99 Other disorders of the nervous system
0.963 0.037 0.000
Chapter II Neoplasms
0.960 0.040 0.000
N95 Menopausal and other perimenopausal disorders
0.958 0.042 0.000
Chapter XX External causes of morbidity and mortality
0.957 0.043 0.000
I10 Essential (primary) hypertension
0.951 0.049 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.949 0.051 0.000
N93 Other abnormal uterine and vaginal bleeding
0.947 0.053 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.943 0.057 0.000
I05-I09 Chronic rheumatic heart diseases
0.941 0.059 0.000
M80-M85 Disorders of bone density and structure
0.940 0.060 0.000
C64-C68 Malignant neoplasms of urinary tract
0.937 0.063 0.000
D64 Other anaemias
0.937 0.063 0.000
N93.9 Abnormal uterine and vaginal bleeding, unspecified
0.935 0.065 0.000
S00-S09 Injuries to the head
0.934 0.066 0.000
N97 Female infertility
0.934 0.066 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.934 0.066 0.000
I84.6 Residual haemorrhoidal skin tags
0.932 0.068 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.931 0.069 0.000
M25 Other joint disorders, not elsewhere classified
0.930 0.070 0.000
N25-N29 Other disorders of kidney and ureter
0.929 0.071 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.927 0.073 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.926 0.074 0.000
S40-S49 Injuries to the shoulder and upper arm
0.925 0.075 0.000
N95.2 Postmenopausal atrophic vaginitis
0.912 0.088 0.000
D64.9 Anaemia, unspecified
0.912 0.088 0.000
I84.7 Unspecified thrombosed haemorrhoids
0.911 0.089 0.000
S00 Superficial injury of head
0.910 0.090 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.908 0.092 0.000
J40-J47 Chronic lower respiratory diseases
0.908 0.092 0.000
I27 Other pulmonary heart diseases
0.906 0.094 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.905 0.095 0.000
J09-J18 Influenza and pneumonia
0.905 0.095 0.000
S20-S29 Injuries to the thorax
0.903 0.097 0.000
I08 Multiple valve diseases
0.903 0.097 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.900 0.100 0.000
Chapter I Certain infectious and parasitic diseases
0.897 0.103 0.000
M24 Other specific joint derangements
0.896 0.104 0.000
N87.0 Mild cervical dysplasia
0.893 0.107 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.891 0.109 0.000
M65-M68 Disorders of synovium and tendon
0.891 0.109 0.000
H60-H62 Diseases of external ear
0.891 0.109 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.889 0.111 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.889 0.111 0.000
N97.9 Female infertility, unspecified
0.887 0.113 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.886 0.114 0.000
I84.5 External haemorrhoids without complication
0.877 0.123 0.000
E00-E07 Disorders of thyroid gland
0.875 0.125 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.873 0.127 0.000
D10-D36 Benign neoplasms
0.870 0.130 0.000
N87.2 Severe cervical dysplasia, not elsewhere classified
0.868 0.132 0.000
J02 Acute pharyngitis
0.867 0.133 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.866 0.134 0.000
I83 Varicose veins of lower extremities
0.866 0.134 0.000
D41.4 Bladder
0.866 0.134 0.000
J06.9 Acute upper respiratory infection, unspecified
0.861 0.139 0.000
N87.9 Dysplasia of cervix uteri, unspecified
0.861 0.139 0.000
C67 Malignant neoplasm of bladder
0.859 0.141 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.859 0.141 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.857 0.143 0.000
M60-M63 Disorders of muscles
0.857 0.143 0.000
E04 Other non-toxic goitre
0.856 0.144 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.855 0.145 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.855 0.145 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.852 0.148 0.000
J84 Other interstitial pulmonary diseases
0.852 0.148 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.852 0.148 0.000
G30-G32 Other degenerative diseases of the nervous system
0.851 0.149 0.000
J47 Bronchiectasis
0.850 0.150 0.000
D68 Other coagulation defects
0.846 0.154 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.845 0.155 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.843 0.157 0.000
M86-M90 Other osteopathies
0.840 0.160 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.840 0.160 0.000
D27 Benign neoplasm of ovary
0.838 0.162 0.000
E20-E35 Disorders of other endocrine glands
0.838 0.162 0.000
I27.0 Primary pulmonary hypertension
0.836 0.164 0.000
G90 Disorders of autonomic nervous system
0.835 0.165 0.000
I12 Hypertensive renal disease
0.834 0.166 0.000
M25.8 Other specified joint disorders
0.834 0.166 0.000
J20-J22 Other acute lower respiratory infections
0.833 0.167 0.000
M91-M94 Chondropathies
0.831 0.169 0.000
E04.1 Non-toxic single thyroid nodule
0.831 0.169 0.000
I27.2 Other secondary pulmonary hypertension
0.829 0.171 0.000
G44 Other headache syndromes
0.829 0.171 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.828 0.172 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.828 0.172 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.828 0.172 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.826 0.174 0.000
H90-H95 Other disorders of ear
0.826 0.174 0.000
M21 Other acquired deformities of limbs
0.825 0.175 0.000
M70-M79 Other soft tissue disorders
0.824 0.176 0.000
N10-N16 Renal tubulo-interstitial diseases
0.823 0.177 0.000
S00.1 Contusion of eyelid and periocular area
0.822 0.178 0.000
M22 Disorders of patella
0.821 0.179 0.000
G93 Other disorders of brain
0.820 0.180 0.000
N95.0 Postmenopausal bleeding
0.819 0.181 0.000
D61 Other aplastic anaemias
0.817 0.183 0.000
J80 Adult respiratory distress syndrome
0.817 0.183 0.000
G62 Other polyneuropathies
0.814 0.186 0.000
N60-N64 Disorders of breast
0.814 0.186 0.000
S00.9 Superficial injury of head, part unspecified
0.814 0.186 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.812 0.188 0.000
G95 Other diseases of spinal cord
0.812 0.188 0.000
M80 Osteoporosis with pathological fracture
0.811 0.189 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.808 0.192 0.000
G47 Sleep disorders
0.807 0.193 0.000
W00-W19 Falls
0.806 0.194 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.805 0.195 0.000
I87 Other disorders of veins
0.803 0.197 0.000
I84.1 Internal haemorrhoids with other complications
0.803 0.197 0.000
T90 Sequelae of injuries of head
0.802 0.198 0.000
G40.5 Special epileptic syndromes
0.802 0.198 0.000
N99-N99 Other disorders of the genitourinary system
0.802 0.198 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.800 0.199 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.800 0.200 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.799 0.201 0.000
D25 Leiomyoma of uterus
0.797 0.203 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.797 0.203 0.000
S10-S19 Injuries to the neck
0.796 0.204 0.000
J00 Acute nasopharyngitis [common cold]
0.796 0.204 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.795 0.205 0.000
J02.9 Acute pharyngitis, unspecified
0.795 0.205 0.000
M85 Other disorders of bone density and structure
0.795 0.205 0.000
S06 Intracranial injury
0.794 0.206 0.000
M84 Disorders of continuity of bone
0.793 0.207 0.000
S22.0 Fracture of thoracic vertebra
0.792 0.208 0.000
M20 Acquired deformities of fingers and toes
0.792 0.208 0.000
B95-B98 Bacterial, viral and other infectious agents
0.792 0.208 0.000
J46 Status asthmaticus
0.786 0.214 0.000
H60 Otitis externa
0.785 0.215 0.000
T00-T07 Injuries involving multiple body regions
0.785 0.215 0.000
O60-O75 Complications of labour and delivery
0.783 0.217 0.000
N89 Other noninflammatory disorders of vagina
0.782 0.218 0.000
N28.9 Disorder of kidney and ureter, unspecified
0.781 0.219 0.000
Chapter XXII Codes for special purposes
0.781 0.219 0.000
N25 Disorders resulting from impaired renal tubular function
0.780 0.220 0.000
D80-D89 Certain disorders involving the immune mechanism
0.780 0.220 0.000
T93 Sequelae of injuries of lower limb
0.778 0.222 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.777 0.223 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.777 0.223 0.000
G40.8 Other epilepsy
0.777 0.223 0.000
M25.84 Other specified joint disorders (Hand)
0.777 0.223 0.000
N95.8 Other specified menopausal and perimenopausal disorders
0.776 0.224 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.775 0.225 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.774 0.226 0.000
N83.1 Corpus luteum cyst
0.774 0.226 0.000
G62.9 Polyneuropathy, unspecified
0.774 0.226 0.000
M67 Other disorders of synovium and tendon
0.773 0.227 0.000
N88 Other noninflammatory disorders of cervix uteri
0.772 0.228 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.772 0.228 0.000
D26 Other benign neoplasms of uterus
0.771 0.229 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.770 0.230 0.000
J18 Pneumonia, organism unspecified
0.770 0.230 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.769 0.231 0.000
N83.5 Torsion of ovary, ovarian pedicle and Fallopian tube
0.768 0.232 0.000
I82 Other venous embolism and thrombosis
0.767 0.233 0.000
H61 Other disorders of external ear
0.766 0.234 0.000
W50-W64 Exposure to animate mechanical forces
0.766 0.234 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.764 0.235 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.764 0.236 0.000
D46 Myelodysplastic syndromes
0.764 0.236 0.000
N87.1 Moderate cervical dysplasia
0.763 0.237 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.762 0.238 0.000
I85 Oesophageal varices
0.761 0.238 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.761 0.239 0.000
H65-H75 Diseases of middle ear and mastoid
0.761 0.239 0.000
M24.1 Other articular cartilage disorders
0.760 0.240 0.000
S42 Fracture of shoulder and upper arm
0.760 0.240 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.760 0.240 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.758 0.242 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.757 0.243 0.000
G96 Other disorders of central nervous system
0.757 0.243 0.000
M62 Other disorders of muscle
0.755 0.245 0.000
J81 Pulmonary oedema
0.753 0.247 0.000
J42 Unspecified chronic bronchitis
0.752 0.248 0.000
O85-O92 Complications predominantly related to the puerperium
0.752 0.248 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.751 0.249 0.000
T79-T79 Certain early complications of trauma
0.749 0.251 0.000
S22.00 Fracture of thoracic vertebra (closed)
0.749 0.251 0.000
D75 Other diseases of blood and blood-forming organs
0.748 0.252 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.748 0.252 0.000
I08.8 Other multiple valve diseases
0.747 0.253 0.000
N13 Obstructive and reflux uropathy
0.744 0.256 0.000
G90.0 Idiopathic peripheral autonomic neuropathy
0.743 0.257 0.000
B02 Zoster [herpes zoster]
0.743 0.257 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.742 0.258 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.742 0.258 0.000
N82 Fistulae involving female genital tract
0.742 0.258 0.000
M31 Other necrotising vasculopathies
0.742 0.258 0.000
S90-S99 Injuries to the ankle and foot
0.741 0.259 0.000
D68.5 Primary Thrombophilia
0.741 0.259 0.000
Y40 Systemic antibiotics
0.741 0.259 0.000
N85.9 Noninflammatory disorder of uterus, unspecified
0.740 0.260 0.000
X60-X84 Intentional self-harm
0.740 0.260 0.000
M25.5 Pain in joint
0.740 0.260 0.000
E04.2 Non-toxic multinodular goitre
0.739 0.261 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.738 0.261 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.738 0.262 0.000
C67.9 Bladder, unspecified
0.737 0.263 0.000
N63 Unspecified lump in breast
0.737 0.263 0.000
M40-M43 Deforming dorsopathies
0.736 0.264 0.000
J18.1 Lobar pneumonia, unspecified
0.736 0.264 0.000
G03 Meningitis due to other and unspecified causes
0.735 0.264 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.735 0.265 0.000
N85.6 Intra-uterine synechiae
0.735 0.265 0.000
C66 Malignant neoplasm of ureter
0.733 0.267 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.730 0.270 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.730 0.270 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.730 0.270 0.000
D68.2 Hereditary deficiency of other clotting factors
0.730 0.270 0.000
I89.0 Lymphoedema, not elsewhere classified
0.729 0.271 0.000
N94.1 Dyspareunia
0.728 0.272 0.000
E40-E46 Malnutrition
0.728 0.272 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.728 0.272 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.728 0.272 0.000
M00-M03 Infectious arthropathies
0.727 0.273 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.727 0.273 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.726 0.274 0.000
M25.3 Other instability of joint
0.726 0.274 0.000
J22 Unspecified acute lower respiratory infection
0.725 0.275 0.000
D25.1 Intramural leiomyoma of uterus
0.724 0.276 0.000
Y60.0 During surgical operation
0.723 0.277 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.723 0.277 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.723 0.277 0.000
D35.0 Adrenal gland
0.723 0.277 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.721 0.279 0.000
S43.0 Dislocation of shoulder joint
0.719 0.281 0.000
G93.3 Postviral fatigue syndrome
0.719 0.281 0.000
D72 Other disorders of white blood cells
0.718 0.282 0.000
B25-B34 Other viral diseases
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
N98 Complications associated with artificial fertilisation
0.717 0.283 0.000
N91 Absent, scanty and rare menstruation
0.717 0.283 0.000
N96 Habitual aborter
0.717 0.283 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.716 0.283 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.716 0.283 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.716 0.283 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.716 0.283 0.000
H90 Conductive and sensorineural hearing loss
0.716 0.284 0.000
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.715 0.285 0.000
I88 Nonspecific lymphadenitis
0.714 0.286 0.000
T33-T35 Frostbite
0.714 0.286 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.714 0.286 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.713 0.287 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.713 0.287 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.713 0.287 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.712 0.288 0.000
N83.0 Follicular cyst of ovary
0.711 0.288 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.711 0.289 0.000
M82 Osteoporosis in diseases classified elsewhere
0.710 0.290 0.000
M25.4 Effusion of joint
0.710 0.290 0.000
N83.9 Noninflammatory disorder of ovary, Fallopian tube and broad ligament, unspecified
0.708 0.292 0.000
N83.7 Haematoma of broad ligament
0.708 0.292 0.000
N83.6 Haematosalpinx
0.708 0.292 0.000
N83.4 Prolapse and hernia of ovary and Fallopian tube
0.708 0.292 0.000
D61.9 Aplastic anaemia, unspecified
0.706 0.294 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.706 0.294 0.000
M33 Dermatopolymyositis
0.706 0.294 0.000
M32 Systemic lupus erythematosus
0.706 0.294 0.000
M30 Polyarteritis nodosa and related conditions
0.706 0.294 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.706 0.294 0.000
T91 Sequelae of injuries of neck and trunk
0.705 0.294 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.704 0.295 0.000
S00.8 Superficial injury of other parts of head
0.704 0.295 0.000
D55-D59 Haemolytic anaemias
0.704 0.295 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.703 0.297 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.703 0.297 0.000
Q50-Q56 Congenital malformations of genital organs
0.702 0.297 0.000
M65 Synovitis and tenosynovitis
0.702 0.298 0.000
H80-H83 Diseases of inner ear
0.701 0.299 0.000
E27 Other disorders of adrenal gland
0.701 0.299 0.000
I13 Hypertensive heart and renal disease
0.700 0.300 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.699 0.301 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.698 0.302 0.000
D25.9 Leiomyoma of uterus, unspecified
0.698 0.302 0.000
I87.2 Venous insufficiency (chronic) (peripheral)
0.698 0.302 0.000
M21.4 Flat foot [pes planus] (acquired)
0.698 0.302 0.000
N28.1 Cyst of kidney, acquired
0.698 0.302 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.697 0.302 0.000
N85.4 Malposition of uterus
0.697 0.303 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.696 0.303 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.696 0.303 0.000
C71 Malignant neoplasm of brain
0.696 0.304 0.000
S09 Other and unspecified injuries of head
0.696 0.304 0.000
C65 Malignant neoplasm of renal pelvis
0.696 0.304 0.000
N60 Benign mammary dysplasia
0.696 0.304 0.000
H60.1 Cellulitis of external ear
0.695 0.305 0.000
I12.0 Hypertensive renal disease with renal failure
0.695 0.305 0.000
N83.3 Acquired atrophy of ovary and Fallopian tube
0.694 0.305 0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)
0.694 0.305 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.692 0.308 0.000
S05 Injury of eye and orbit
0.692 0.308 0.000
N00-N08 Glomerular diseases
0.692 0.308 0.000
M22.4 Chondromalacia patellae
0.691 0.309 0.000
M85.8 Other specified disorders of bone density and structure
0.691 0.309 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.691 0.309 0.000
T93.9 Sequelae of unspecified injury of lower limb
0.691 0.309 0.000
B99-B99 Other infectious diseases
0.690 0.310 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.690 0.310 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.690 0.310 0.000
G92 Toxic encephalopathy
0.690 0.310 0.000
I86 Varicose veins of other sites
0.690 0.310 0.000
V80-V89 Other land transport accidents
0.689 0.311 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.689 0.311 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.688 0.311 0.000
D63.0 Anaemia in neoplastic disease
0.688 0.312 0.000
S00.3 Superficial injury of nose
0.688 0.312 0.000
G00 Bacterial meningitis, not elsewhere classified
0.688 0.312 0.000
B00 Herpesviral [herpes simplex] infections
0.687 0.313 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.687 0.313 0.000
N95.9 Menopausal and perimenopausal disorder, unspecified
0.687 0.313 0.000
G44.2 Tension-type headache
0.687 0.313 0.000
I15 Secondary hypertension
0.686 0.313 0.000
Y35-Y36 Legal intervention and operations of war
0.686 0.314 0.000
Y10-Y34 Event of undetermined intent
0.686 0.314 0.000
Y00-Y09 Assault
0.686 0.314 0.000
X85-X99 Assault
0.686 0.314 0.000
X50-X57 Overexertion, travel and privation
0.686 0.314 0.000
X30-X39 Exposure to forces of nature
0.686 0.314 0.000
X20-X29 Contact with venomous animals and plants
0.686 0.314 0.000
X10-X19 Contact with heat and hot substances
0.686 0.314 0.000
X00-X09 Exposure to smoke, fire and flames
0.686 0.314 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.686 0.314 0.000
W75-W84 Other accidental threats to breathing
0.686 0.314 0.000
W65-W74 Accidental drowning and submersion
0.686 0.314 0.000
V98-V99 Other and unspecified transport accidents
0.686 0.314 0.000
V95-V97 Air and space transport accidents
0.686 0.314 0.000
V90-V94 Water transport accidents
0.686 0.314 0.000
V70-V79 Bus occupant injured in transport accident
0.686 0.314 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.686 0.314 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.686 0.314 0.000
V40-V49 Car occupant injured in transport accident
0.686 0.314 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.686 0.314 0.000
V01-V09 Pedestrian injured in transport accident
0.686 0.314 0.000
T92 Sequelae of injuries of upper limb
0.686 0.314 0.000
J45 Asthma
0.685 0.315 0.000
G41 Status epilepticus
0.685 0.315 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.684 0.316 0.000
D26.1 Corpus uteri
0.684 0.316 0.000
B02.9 Zoster without complication
0.684 0.316 0.000
J60-J70 Lung diseases due to external agents
0.684 0.316 0.000
L08 Other local infections of skin and subcutaneous tissue
0.684 0.316 0.000
D35.1 Parathyroid gland
0.684 0.316 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.684 0.316 0.000
M62.8 Other specified disorders of muscle
0.682 0.318 0.000
M67.8 Other specified disorders of synovium and tendon
0.681 0.319 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.680 0.320 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.680 0.320 0.000
M05-M14 Inflammatory polyarthropathies
0.680 0.320 0.000
D16 Benign neoplasm of bone and articular cartilage
0.680 0.320 0.000
T90.4 Sequelae of injury of eye and orbit
0.679 0.321 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.679 0.321 0.000
S40 Superficial injury of shoulder and upper arm
0.679 0.321 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.678 0.321 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.678 0.322 0.000
D68.9 Coagulation defect, unspecified
0.677 0.323 0.000
G30 Alzheimer's disease
0.676 0.323 0.000
M25.0 Haemarthrosis
0.676 0.324 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.676 0.324 0.000
I07 Rheumatic tricuspid valve diseases
0.676 0.324 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.676 0.324 0.000
G95.9 Disease of spinal cord, unspecified
0.675 0.325 0.000
E50-E64 Other nutritional deficiencies
0.675 0.325 0.000
G47.9 Sleep disorder, unspecified
0.675 0.325 0.000
J01 Acute sinusitis
0.675 0.325 0.000
I09 Other rheumatic heart diseases
0.675 0.325 0.000
I06 Rheumatic aortic valve diseases
0.675 0.325 0.000
L40-L45 Papulosquamous disorders
0.675 0.325 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.674 0.326 0.000
M83 Adult osteomalacia
0.674 0.326 0.000
N25.8 Other disorders resulting from impaired renal tubular function
0.674 0.326 0.000
D66 Hereditary factor VIII deficiency
0.673 0.327 0.000
S06.5 Traumatic subdural haemorrhage
0.673 0.327 0.000
C67.0 Trigone of bladder
0.672 0.328 0.000
N85.1 Endometrial adenomatous hyperplasia
0.672 0.328 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.672 0.328 0.000
D64.8 Other specified anaemias
0.671 0.328 0.000
D64.4 Congenital dyserythropoietic anaemia
0.671 0.328 0.000
D64.3 Other sideroblastic anaemias
0.671 0.328 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.671 0.328 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.671 0.328 0.000
D64.0 Hereditary sideroblastic anaemia
0.671 0.328 0.000
J84.9 Interstitial pulmonary disease, unspecified
0.671 0.329 0.000
V20-V29 Motorcycle rider injured in transport accident
0.671 0.329 0.000
M20.4 Other hammer toe(s) (acquired)
0.671 0.329 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.670 0.330 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.670 0.330 0.000
D17 Benign lipomatous neoplasm
0.670 0.330 0.000
C67.6 Ureteric orifice
0.670 0.330 0.000
S08 Traumatic amputation of part of head
0.670 0.330 0.000
S07 Crushing injury of head
0.670 0.330 0.000
S04 Injury of cranial nerves
0.670 0.330 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.670 0.330 0.000
N97.8 Female infertility of other origin
0.669 0.331 0.000
N97.4 Female infertility associated with male factors
0.669 0.331 0.000
N97.3 Female infertility of cervical origin
0.669 0.331 0.000
N97.2 Female infertility of uterine origin
0.669 0.331 0.000
N97.0 Female infertility associated with anovulation
0.669 0.331 0.000
I28 Other diseases of pulmonary vessels
0.669 0.331 0.000
M66 Spontaneous rupture of synovium and tendon
0.669 0.331 0.000
M21.2 Flexion deformity
0.669 0.331 0.000
D29 Benign neoplasm of male genital organs
0.669 0.331 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.669 0.331 0.000
M90 Osteopathies in diseases classified elsewhere
0.669 0.331 0.000
D23 Other benign neoplasms of skin
0.668 0.332 0.000
E26 Hyperaldosteronism
0.668 0.332 0.000
I84.0 Internal thrombosed haemorrhoids
0.668 0.332 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.667 0.333 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.667 0.333 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.667 0.333 0.000
M25.2 Flail joint
0.667 0.333 0.000
M25.1 Fistula of joint
0.667 0.333 0.000
I27.9 Pulmonary heart disease, unspecified
0.666 0.333 0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere
0.666 0.334 0.000
N27 Small kidney of unknown cause
0.666 0.334 0.000
N97.1 Female infertility of tubal origin
0.666 0.334 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.665 0.335 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.665 0.335 0.000
T98 Sequelae of other and unspecified effects of external causes
0.664 0.335 0.000
T95 Sequelae of burns, corrosions and frostbite
0.664 0.335 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.664 0.335 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.664 0.335 0.000
S22.1 Multiple fractures of thoracic spine
0.664 0.336 0.000
H93 Other disorders of ear, not elsewhere classified
0.664 0.336 0.000
S48 Traumatic amputation of shoulder and upper arm
0.663 0.337 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.663 0.337 0.000
S44 Injury of nerves at shoulder and upper arm level
0.663 0.337 0.000
S41 Open wound of shoulder and upper arm
0.663 0.337 0.000
S47 Crushing injury of shoulder and upper arm
0.663 0.337 0.000
S22.2 Fracture of sternum
0.663 0.337 0.000
J04 Acute laryngitis and tracheitis
0.662 0.338 0.000
M89 Other disorders of bone
0.662 0.338 0.000
I12.9 Hypertensive renal disease without renal failure
0.662 0.338 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.661 0.338 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.661 0.339 0.000
C51-C58 Malignant neoplasms of female genital organs
0.661 0.339 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.661 0.339 0.000
W14 Fall from tree
0.661 0.339 0.000
C69 Malignant neoplasm of eye and adnexa
0.661 0.339 0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)
0.660 0.340 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.660 0.340 0.000
M25.9 Joint disorder, unspecified
0.660 0.340 0.000
C67.4 Posterior wall of bladder
0.660 0.340 0.000
D75.2 Essential thrombocytosis
0.659 0.341 0.000
S70-S79 Injuries to the hip and thigh
0.659 0.341 0.000
G47.3 Sleep apnoea
0.658 0.342 0.000
M25.87 Other specified joint disorders (Ankle and foot)
0.657 0.343 0.000
G95.0 Syringomyelia and syringobulbia
0.655 0.345 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.655 0.345 0.000
D25.2 Subserosal leiomyoma of uterus
0.654 0.346 0.000
H92 Otalgia and effusion of ear
0.654 0.346 0.000
S20 Superficial injury of thorax
0.653 0.347 0.000
S00.0 Superficial injury of scalp
0.653 0.347 0.000
S42.0 Fracture of clavicle
0.653 0.347 0.000
N90.5 Atrophy of vulva
0.653 0.347 0.000
S00.7 Multiple superficial injuries of head
0.652 0.348 0.000
S00.5 Superficial injury of lip and oral cavity
0.652 0.348 0.000
S00.4 Superficial injury of ear
0.652 0.348 0.000
M20.1 Hallux valgus (acquired)
0.652 0.348 0.000
I84.4 External haemorrhoids with other complications
0.652 0.348 0.000
T66-T78 Other and unspecified effects of external causes
0.652 0.348 0.000
M24.5 Contracture of joint
0.652 0.348 0.000
D31 Benign neoplasm of eye and adnexa
0.651 0.349 0.000
G64 Other disorders of peripheral nervous system
0.651 0.349 0.000
G61 Inflammatory polyneuropathy
0.651 0.349 0.000
J41 Simple and mucopurulent chronic bronchitis
0.651 0.349 0.000
Y40.0 Penicillins
0.650 0.350 0.000
C88 Malignant immunoproliferative diseases
0.650 0.350 0.000
M93 Other osteochondropathies
0.650 0.350 0.000
I27.8 Other specified pulmonary heart diseases
0.650 0.350 0.000
I27.1 Kyphoscoliotic heart disease
0.650 0.350 0.000
I11 Hypertensive heart disease
0.650 0.350 0.000
N13.4 Hydroureter
0.650 0.350 0.000
D63.8 Anaemia in other chronic diseases classified elsewhere
0.649 0.350 0.000
J06.8 Other acute upper respiratory infections of multiple sites
0.649 0.351 0.000
J06.0 Acute laryngopharyngitis
0.649 0.351 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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