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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs75038438
log Bayes Factor = 18.8448
Chromosome 14   position 60,996,166  (GRCh37) Explore rs75038438 on Ensembl!
Variant rs75038438 is part of Cluster X0277

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
J40-J47 Chronic lower respiratory diseases
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
J45 Asthma
0.999 0.001 0.000
Chapter XXI Factors influencing health status and contact with health services
0.998 0.002 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.998 0.002 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.998 0.002 0.000
Chapter VII Diseases of the eye and adnexa
0.996 0.004 0.000
Chapter V Mental and behavioural disorders
0.996 0.004 0.000
J45.9 Asthma, unspecified
0.995 0.005 0.000
Chapter I Certain infectious and parasitic diseases
0.994 0.006 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.993 0.007 0.000
J44 Other chronic obstructive pulmonary disease
0.991 0.009 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.990 0.010 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.987 0.013 0.000
Z93 Artificial opening status
0.987 0.013 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.983 0.017 0.000
I35 Nonrheumatic aortic valve disorders
0.983 0.017 0.000
B95-B98 Bacterial, viral and other infectious agents
0.976 0.024 0.000
H30-H36 Disorders of choroid and retina
0.975 0.025 0.000
E70-E90 Metabolic disorders
0.974 0.026 0.000
I45 Other conduction disorders
0.967 0.033 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.957 0.043 0.000
O60-O75 Complications of labour and delivery
0.947 0.053 0.000
Z93.2 Ileostomy status
0.945 0.055 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.943 0.057 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.942 0.058 0.000
I35.0 Aortic (valve) stenosis
0.940 0.060 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.939 0.061 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.938 0.062 0.000
I50 Heart failure
0.934 0.066 0.000
I45.1 Other and unspecified right bundle-branch block
0.931 0.069 0.000
J45.0 Predominantly allergic asthma
0.927 0.073 0.000
F30-F39 Mood [affective] disorders
0.926 0.074 0.000
Z36 Antenatal screening
0.924 0.076 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.921 0.079 0.000
H43-H45 Disorders of vitreous body and globe
0.919 0.081 0.000
E00-E07 Disorders of thyroid gland
0.917 0.083 0.000
I05-I09 Chronic rheumatic heart diseases
0.916 0.084 0.000
H35 Other retinal disorders
0.914 0.086 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.909 0.091 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.909 0.091 0.000
H33 Retinal detachments and breaks
0.903 0.097 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.902 0.098 0.000
M50-M54 Other dorsopathies
0.893 0.107 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.893 0.107 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.890 0.110 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.889 0.111 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.889 0.111 0.000
E86 Volume depletion
0.886 0.114 0.000
Chapter VI Diseases of the nervous system
0.883 0.117 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.882 0.118 0.000
T81 Complications of procedures, not elsewhere classified
0.882 0.118 0.000
E83 Disorders of mineral metabolism
0.881 0.119 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.879 0.121 0.000
O62 Abnormalities of forces of labour
0.878 0.122 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.876 0.124 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.876 0.124 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.875 0.125 0.000
I50.0 Congestive heart failure
0.868 0.132 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.868 0.132 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.868 0.132 0.000
Z85 Personal history of malignant neoplasm
0.867 0.133 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.866 0.134 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.865 0.135 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.865 0.135 0.000
Chapter XI Diseases of the digestive system
0.865 0.135 0.000
A30-A49 Other bacterial diseases
0.863 0.137 0.000
I42 Cardiomyopathy
0.863 0.137 0.000
Z93.5 Cystostomy status
0.861 0.139 0.000
Z93.3 Colostomy status
0.860 0.140 0.000
O42 Premature rupture of membranes
0.860 0.140 0.000
K90-K93 Other diseases of the digestive system
0.859 0.141 0.000
R41.0 Disorientation, unspecified
0.858 0.142 0.000
H43 Disorders of vitreous body
0.858 0.142 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.855 0.145 0.000
I35.1 Aortic (valve) insufficiency
0.854 0.146 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.853 0.147 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.852 0.148 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.851 0.149 0.000
I60-I69 Cerebrovascular diseases
0.851 0.149 0.000
J46 Status asthmaticus
0.846 0.154 0.000
Z93.1 Gastrostomy status
0.845 0.155 0.000
Z36.8 Other antenatal screening
0.842 0.158 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.841 0.159 0.000
S00-S09 Injuries to the head
0.840 0.160 0.000
I51 Complications and ill-defined descriptions of heart disease
0.837 0.163 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.836 0.164 0.000
Z89 Acquired absence of limb
0.835 0.165 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.831 0.169 0.000
F33 Recurrent depressive disorder
0.831 0.169 0.000
Z95.4 Presence of other heart-valve replacement
0.828 0.172 0.000
M54 Dorsalgia
0.825 0.175 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.825 0.175 0.000
S32 Fracture of lumbar spine and pelvis
0.824 0.176 0.000
F31 Bipolar affective disorder
0.822 0.178 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.820 0.180 0.000
S20-S29 Injuries to the thorax
0.820 0.180 0.000
E83.5 Disorders of calcium metabolism
0.817 0.182 0.000
Chapter XXII Codes for special purposes
0.816 0.184 0.000
O36 Maternal care for other known or suspected foetal problems
0.816 0.184 0.000
Z83 Family history of other specific disorders
0.815 0.185 0.000
H33.0 Retinal detachment with retinal break
0.814 0.186 0.000
O47 False labour
0.812 0.188 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.811 0.189 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.811 0.189 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.811 0.189 0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods
0.810 0.190 0.000
F40 Phobic anxiety disorders
0.808 0.192 0.000
J81 Pulmonary oedema
0.806 0.194 0.000
I38 Endocarditis, valve unspecified
0.804 0.196 0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems
0.803 0.197 0.000
E04 Other non-toxic goitre
0.803 0.197 0.000
M80-M85 Disorders of bone density and structure
0.802 0.198 0.000
O62.2 Other uterine inertia
0.800 0.200 0.000
O41 Other disorders of amniotic fluid and membranes
0.800 0.200 0.000
I95 Hypotension
0.799 0.201 0.000
I08 Multiple valve diseases
0.798 0.202 0.000
H10-H13 Disorders of conjunctiva
0.798 0.202 0.000
R42 Dizziness and giddiness
0.793 0.207 0.000
I50.1 Left ventricular failure
0.793 0.207 0.000
F99-F99 Unspecified mental disorder
0.792 0.208 0.000
M45-M49 Spondylopathies
0.791 0.209 0.000
F80-F89 Disorders of psychological development
0.791 0.209 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.789 0.211 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.788 0.212 0.000
M51 Other intervertebral disk disorders
0.787 0.213 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.787 0.213 0.000
K90 Intestinal malabsorption
0.786 0.214 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.784 0.216 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.783 0.217 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.782 0.218 0.000
I45.5 Other specified heart block
0.782 0.218 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.781 0.219 0.000
Z39 Postpartum care and examination
0.781 0.219 0.000
R30-R39 Symptoms and signs involving the urinary system
0.781 0.219 0.000
A41 Other septicaemia
0.781 0.219 0.000
O00-O08 Pregnancy with abortive outcome
0.781 0.219 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.780 0.220 0.000
O66 Other obstructed labour
0.778 0.221 0.000
J00-J06 Acute upper respiratory infections
0.778 0.222 0.000
O63 Long labour
0.777 0.223 0.000
S40-S49 Injuries to the shoulder and upper arm
0.777 0.223 0.000
H35.8 Other specified retinal disorders
0.777 0.223 0.000
H33.3 Retinal breaks without detachment
0.776 0.224 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.776 0.224 0.000
I49 Other cardiac arrhythmias
0.776 0.224 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.773 0.227 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.773 0.227 0.000
B25-B34 Other viral diseases
0.773 0.227 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.772 0.228 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.771 0.229 0.000
Z92 Personal history of medical treatment
0.770 0.230 0.000
O43 Placental disorders
0.770 0.230 0.000
K55-K64 Other diseases of intestines
0.770 0.230 0.000
J40 Bronchitis, not specified as acute or chronic
0.770 0.230 0.000
I31 Other diseases of pericardium
0.769 0.231 0.000
M54.5 Low back pain
0.769 0.231 0.000
H55-H59 Other disorders of eye and adnexa
0.769 0.231 0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters
0.769 0.231 0.000
J20-J22 Other acute lower respiratory infections
0.768 0.232 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.768 0.232 0.000
I05 Rheumatic mitral valve diseases
0.767 0.233 0.000
E05.9 Thyrotoxicosis, unspecified
0.767 0.233 0.000
E20-E35 Disorders of other endocrine glands
0.767 0.233 0.000
I33 Acute and subacute endocarditis
0.766 0.234 0.000
I51.8 Other ill-defined heart diseases
0.766 0.234 0.000
H43.8 Other disorders of vitreous body
0.763 0.237 0.000
K91.4 Colostomy and enterostomy malfunction
0.763 0.237 0.000
H35.0 Background retinopathy and retinal vascular changes
0.762 0.238 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.762 0.238 0.000
Z60 Problems related to social environment
0.761 0.239 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.761 0.239 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.760 0.240 0.000
K92 Other diseases of digestive system
0.758 0.242 0.000
J90-J94 Other diseases of pleura
0.758 0.242 0.000
F41 Other anxiety disorders
0.757 0.243 0.000
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods
0.756 0.244 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.755 0.245 0.000
Z35 Supervision of high-risk pregnancy
0.755 0.245 0.000
H53-H54 Visual disturbances and blindness
0.754 0.246 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.753 0.247 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.753 0.247 0.000
E40-E46 Malnutrition
0.750 0.250 0.000
T79-T79 Certain early complications of trauma
0.749 0.251 0.000
J47 Bronchiectasis
0.749 0.251 0.000
Z93.0 Tracheostomy status
0.748 0.252 0.000
F31.9 Bipolar affective disorder, unspecified
0.747 0.253 0.000
T86 Failure and rejection of transplanted organs and tissues
0.746 0.254 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.745 0.255 0.000
H43.1 Vitreous haemorrhage
0.745 0.255 0.000
O72 Postpartum haemorrhage
0.744 0.256 0.000
S32.0 Fracture of lumbar vertebra
0.744 0.256 0.000
A80-A89 Viral infections of the central nervous system
0.743 0.257 0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.743 0.257 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.742 0.258 0.000
R40 Somnolence, stupor and coma
0.742 0.258 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.738 0.262 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.736 0.263 0.000
J43 Emphysema
0.734 0.266 0.000
K90.0 Coeliac disease
0.734 0.266 0.000
Z92.3 Personal history of irradiation
0.734 0.266 0.000
G20-G26 Extrapyramidal and movement disorders
0.733 0.267 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.733 0.267 0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours
0.733 0.267 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.732 0.268 0.000
H34 Retinal vascular occlusions
0.730 0.270 0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.729 0.271 0.000
F40.2 Specific (isolated) phobias
0.728 0.272 0.000
M86-M90 Other osteopathies
0.727 0.273 0.000
F43 Reaction to severe stress, and adjustment disorders
0.726 0.274 0.000
B15-B19 Viral hepatitis
0.726 0.274 0.000
H35.6 Retinal haemorrhage
0.726 0.274 0.000
R32 Unspecified urinary incontinence
0.725 0.275 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.725 0.275 0.000
A41.9 Septicaemia, unspecified
0.723 0.277 0.000
H35.3 Degeneration of macula and posterior pole
0.722 0.278 0.000
O62.3 Precipitate labour
0.721 0.279 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.721 0.279 0.000
S90-S99 Injuries to the ankle and foot
0.721 0.279 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.721 0.279 0.000
M51.2 Other specified intervertebral disk displacement
0.720 0.280 0.000
J60-J70 Lung diseases due to external agents
0.720 0.280 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.719 0.280 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.718 0.281 0.000
J09-J18 Influenza and pneumonia
0.718 0.282 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
J41 Simple and mucopurulent chronic bronchitis
0.717 0.283 0.000
J42 Unspecified chronic bronchitis
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I30 Acute pericarditis
0.717 0.283 0.000
J45.8 Mixed asthma
0.716 0.284 0.000
J45.1 Nonallergic asthma
0.716 0.284 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.716 0.284 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.716 0.284 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.716 0.284 0.000
O85-O92 Complications predominantly related to the puerperium
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
S10-S19 Injuries to the neck
0.716 0.284 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.715 0.285 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.715 0.285 0.000
Z36.0 Antenatal screening for chromosomal anomalies
0.714 0.286 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.714 0.286 0.000
F70-F79 Mental retardation
0.714 0.286 0.000
F60-F69 Disorders of adult personality and behaviour
0.714 0.286 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.713 0.287 0.000
B99-B99 Other infectious diseases
0.712 0.288 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.712 0.288 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.712 0.288 0.000
B65-B83 Helminthiases
0.712 0.288 0.000
B50-B64 Protozoal diseases
0.712 0.288 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.712 0.288 0.000
A75-A79 Rickettsioses
0.712 0.288 0.000
A70-A74 Other diseases caused by chlamydiae
0.712 0.288 0.000
A65-A69 Other spirochaetal diseases
0.712 0.288 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.712 0.288 0.000
A20-A28 Certain zoonotic bacterial diseases
0.712 0.288 0.000
A15-A19 Tuberculosis
0.712 0.288 0.000
I95.9 Hypotension, unspecified
0.712 0.288 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.712 0.288 0.000
Z84 Family history of other conditions
0.712 0.288 0.000
Z81 Family history of mental and behavioural disorders
0.712 0.288 0.000
Z95.3 Presence of xenogenic heart valve
0.710 0.290 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.710 0.290 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.710 0.290 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.709 0.291 0.000
Z33 Pregnant state, incidental
0.708 0.291 0.000
O45 Premature separation of placenta [abruptio placentae]
0.708 0.292 0.000
O44 Placenta praevia
0.708 0.292 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.708 0.292 0.000
O33 Maternal care for known or suspected disproportion
0.708 0.292 0.000
O31 Complications specific to multiple gestation
0.708 0.292 0.000
O40 Polyhydramnios
0.708 0.292 0.000
Z93.9 Artificial opening status, unspecified
0.707 0.292 0.000
Z93.8 Other artificial opening status
0.707 0.292 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.707 0.292 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.707 0.293 0.000
I47 Paroxysmal tachycardia
0.707 0.293 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.706 0.294 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.706 0.294 0.000
T87 Complications peculiar to reattachment and amputation
0.705 0.295 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.705 0.295 0.000
I35.9 Aortic valve disorder, unspecified
0.705 0.295 0.000
I35.8 Other aortic valve disorders
0.705 0.295 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.704 0.295 0.000
T66-T78 Other and unspecified effects of external causes
0.704 0.296 0.000
F33.9 Recurrent depressive disorder, unspecified
0.703 0.297 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.703 0.297 0.000
O30 Multiple gestation
0.702 0.298 0.000
M81 Osteoporosis without pathological fracture
0.702 0.298 0.000
H18 Other disorders of cornea
0.701 0.299 0.000
M20-M25 Other joint disorders
0.700 0.300 0.000
Z89.5 Acquired absence of leg at or below knee
0.699 0.301 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.699 0.301 0.000
H31 Other disorders of choroid
0.699 0.301 0.000
H30 Chorioretinal inflammation
0.699 0.301 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.699 0.301 0.000
S70-S79 Injuries to the hip and thigh
0.699 0.301 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.699 0.301 0.000
E88 Other metabolic disorders
0.698 0.302 0.000
E85 Amyloidosis
0.698 0.302 0.000
E84 Cystic fibrosis
0.698 0.302 0.000
E79 Disorders of purine and pyrimidine metabolism
0.698 0.302 0.000
E77 Disorders of glycoprotein metabolism
0.698 0.302 0.000
E76 Disorders of glycosaminoglycan metabolism
0.698 0.302 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.698 0.302 0.000
E74 Other disorders of carbohydrate metabolism
0.698 0.302 0.000
E73 Lactose intolerance
0.698 0.302 0.000
E72 Other disorders of amino-acid metabolism
0.698 0.302 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.698 0.302 0.000
E70 Disorders of aromatic amino-acid metabolism
0.698 0.302 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.698 0.302 0.000
Z95.2 Presence of prosthetic heart valve
0.697 0.303 0.000
Z83.5 Family history of eye and ear disorders
0.697 0.303 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.696 0.304 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.696 0.304 0.000
E89.0 Postprocedural hypothyroidism
0.695 0.305 0.000
Chapter XX External causes of morbidity and mortality
0.694 0.306 0.000
S02 Fracture of skull and facial bones
0.694 0.306 0.000
G81 Hemiplegia
0.694 0.306 0.000
I42.0 Dilated cardiomyopathy
0.693 0.307 0.000
I45.9 Conduction disorder, unspecified
0.693 0.307 0.000
I45.8 Other specified conduction disorders
0.693 0.307 0.000
I45.6 Preexcitation syndrome
0.693 0.307 0.000
I45.4 Nonspecific intraventricular block
0.693 0.307 0.000
I45.3 Trifascicular block
0.693 0.307 0.000
I45.2 Bifascicular block
0.693 0.307 0.000
I45.0 Right fascicular block
0.693 0.307 0.000
E04.2 Non-toxic multinodular goitre
0.693 0.307 0.000
O42.9 Premature rupture of membranes, unspecified
0.693 0.307 0.000
G70-G73 Diseases of myoneural junction and muscle
0.692 0.307 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.692 0.307 0.000
H20 Iridocyclitis
0.692 0.308 0.000
J80 Adult respiratory distress syndrome
0.692 0.308 0.000
Z97 Presence of other devices
0.691 0.309 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.689 0.311 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.689 0.311 0.000
M54.56 Low back pain (Lumbar region)
0.689 0.311 0.000
S80-S89 Injuries to the knee and lower leg
0.688 0.312 0.000
Z34 Supervision of normal pregnancy
0.686 0.313 0.000
E06 Thyroiditis
0.686 0.314 0.000
S32.00 Fracture of lumbar vertebra (closed)
0.686 0.314 0.000
Z38 Liveborn infants according to place of birth
0.686 0.314 0.000
Z32 Pregnancy examination and test
0.686 0.314 0.000
Z31 Procreative management
0.686 0.314 0.000
Z95.0 Presence of cardiac pacemaker
0.685 0.315 0.000
O24 Diabetes mellitus in pregnancy
0.685 0.315 0.000
K92.2 Gastro-intestinal haemorrhage, unspecified
0.685 0.315 0.000
M40-M43 Deforming dorsopathies
0.684 0.316 0.000
I07 Rheumatic tricuspid valve diseases
0.684 0.316 0.000
K50-K52 Noninfective enteritis and colitis
0.684 0.316 0.000
Z60.2 Living alone
0.683 0.316 0.000
L60-L75 Disorders of skin appendages
0.683 0.317 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.683 0.317 0.000
O48 Prolonged pregnancy
0.682 0.318 0.000
H44 Disorders of globe
0.682 0.318 0.000
M54.59 Low back pain (Site unspecified)
0.680 0.320 0.000
I42.2 Other hypertrophic cardiomyopathy
0.680 0.320 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.679 0.321 0.000
O74 Complications of anaesthesia during labour and delivery
0.679 0.321 0.000
O73 Retained placenta and membranes, without haemorrhage
0.679 0.321 0.000
O71 Other obstetric trauma
0.679 0.321 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.679 0.321 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.679 0.321 0.000
O61 Failed induction of labour
0.679 0.321 0.000
O60 Preterm delivery
0.679 0.321 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.678 0.322 0.000
H36 Retinal disorders in diseases classified elsewhere
0.678 0.322 0.000
H25-H28 Disorders of lens
0.677 0.323 0.000
I42.9 Cardiomyopathy, unspecified
0.676 0.324 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.676 0.324 0.000
M91-M94 Chondropathies
0.675 0.324 0.000
M60-M63 Disorders of muscles
0.675 0.324 0.000
M00-M03 Infectious arthropathies
0.675 0.324 0.000
E83.4 Disorders of magnesium metabolism
0.674 0.326 0.000
J84 Other interstitial pulmonary diseases
0.674 0.326 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.673 0.326 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.672 0.328 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.672 0.328 0.000
T85.2 Mechanical complication of intraocular lens
0.672 0.328 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.672 0.328 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.672 0.328 0.000
K63 Other diseases of intestine
0.671 0.329 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.671 0.329 0.000
K59 Other functional intestinal disorders
0.669 0.331 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.669 0.331 0.000
Chapter VIII Diseases of the ear and mastoid process
0.668 0.332 0.000
H21 Other disorders of iris and ciliary body
0.668 0.332 0.000
O20 Haemorrhage in early pregnancy
0.667 0.333 0.000
I34 Nonrheumatic mitral valve disorders
0.667 0.333 0.000
K92.0 Haematemesis
0.666 0.334 0.000
E04.9 Non-toxic goitre, unspecified
0.666 0.334 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.666 0.334 0.000
O41.0 Oligohydramnios
0.666 0.334 0.000
L81 Other disorders of pigmentation
0.666 0.334 0.000
M54.3 Sciatica
0.665 0.335 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.665 0.335 0.000
F38 Other mood [affective] disorders
0.664 0.336 0.000
F34 Persistent mood [affective] disorders
0.664 0.336 0.000
F30 Manic episode
0.664 0.336 0.000
F39 Unspecified mood [affective] disorder
0.664 0.336 0.000
M54.2 Cervicalgia
0.664 0.336 0.000
R45 Symptoms and signs involving emotional state
0.662 0.338 0.000
Z36.5 Antenatal screening for isoimmunisation
0.662 0.338 0.000
Z36.2 Other antenatal screening based on amniocentesis
0.662 0.338 0.000
Z36.1 Antenatal screening for raised alphafetoprotein level
0.662 0.338 0.000
B35-B49 Mycoses
0.662 0.338 0.000
R40.0 Somnolence
0.662 0.338 0.000
I05.9 Mitral valve disease, unspecified
0.661 0.339 0.000
Z93.6 Other artificial openings of urinary tract status
0.660 0.340 0.000
F48 Other neurotic disorders
0.660 0.340 0.000
F44 Dissociative [conversion] disorders
0.660 0.340 0.000
F42 Obsessive-compulsive disorder
0.660 0.340 0.000
R39 Other symptoms and signs involving the urinary system
0.659 0.341 0.000
Z94 Transplanted organ and tissue status
0.659 0.341 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.659 0.341 0.000
S32.1 Fracture of sacrum
0.659 0.341 0.000
I46 Cardiac arrest
0.658 0.342 0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified
0.658 0.342 0.000
I49.9 Cardiac arrhythmia, unspecified
0.658 0.342 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.658 0.342 0.000
E00 Congenital iodine-deficiency syndrome
0.658 0.342 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.658 0.342 0.000
F45 Somatoform disorders
0.657 0.343 0.000
M70-M79 Other soft tissue disorders
0.657 0.343 0.000
I09 Other rheumatic heart diseases
0.657 0.343 0.000
I06 Rheumatic aortic valve diseases
0.657 0.343 0.000
H11 Other disorders of conjunctiva
0.656 0.344 0.000
Z57 Occupational exposure to risk-factors
0.656 0.344 0.000
Z39.0 Care and examination immediately after delivery
0.655 0.344 0.000
H35.9 Retinal disorder, unspecified
0.655 0.345 0.000
H35.7 Separation of retinal layers
0.655 0.345 0.000
H35.5 Hereditary retinal dystrophy
0.655 0.345 0.000
H35.4 Peripheral retinal degeneration
0.655 0.345 0.000
H35.2 Other proliferative retinopathy
0.655 0.345 0.000
H35.1 Retinopathy of prematurity
0.655 0.345 0.000
L89 Decubitus ulcer
0.655 0.345 0.000
M48 Other spondylopathies
0.654 0.346 0.000
S00 Superficial injury of head
0.653 0.347 0.000
E87.2 Acidosis
0.652 0.348 0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified
0.652 0.348 0.000
O34.8 Maternal care for other abnormalities of pelvic organs
0.652 0.348 0.000
O34.7 Maternal care for abnormality of vulva and perineum
0.652 0.348 0.000
O34.6 Maternal care for abnormality of vagina
0.652 0.348 0.000
O34.5 Maternal care for other abnormalities of gravid uterus
0.652 0.348 0.000
O34.4 Maternal care for other abnormalities of cervix
0.652 0.348 0.000
O34.3 Maternal care for cervical incompetence
0.652 0.348 0.000
O34.1 Maternal care for tumour of corpus uteri
0.652 0.348 0.000
O34.0 Maternal care for congenital malformation of uterus
0.652 0.348 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.652 0.348 0.000
S37 Injury of urinary and pelvic organs
0.652 0.348 0.000
S36 Injury of intra-abdominal organs
0.652 0.348 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.652 0.348 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.652 0.348 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.652 0.348 0.000
S31 Open wound of abdomen, lower back and pelvis
0.652 0.348 0.000
L40-L45 Papulosquamous disorders
0.652 0.348 0.000
J95-J99 Other diseases of the respiratory system
0.651 0.349 0.000
A00-A09 Intestinal infectious diseases
0.651 0.349 0.000
I95.2 Hypotension due to drugs
0.650 0.350 0.000
O36.8 Maternal care for other specified foetal problems
0.650 0.350 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.648 0.352 0.000
O80-O84 Delivery
0.648 0.352 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.648 0.352 0.000
H33.5 Other retinal detachments
0.647 0.352 0.000
H33.4 Traction detachment of retina
0.647 0.352 0.000
H33.1 Retinoschisis and retinal cysts
0.647 0.352 0.000
I08.0 Disorders of both mitral and aortic valves
0.647 0.353 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.647 0.353 0.000
R30 Pain associated with micturition
0.647 0.353 0.000
F99 Mental disorder, not otherwise specified
0.646 0.354 0.000
R34 Anuria and oliguria
0.644 0.356 0.000
E50-E64 Other nutritional deficiencies
0.644 0.356 0.000
O63.1 Prolonged second stage (of labour)
0.644 0.356 0.000
F81 Specific developmental disorders of scholastic skills
0.644 0.356 0.000
Z43 Attention to artificial openings
0.643 0.357 0.000
M53 Other dorsopathies, not elsewhere classified
0.640 0.360 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.640 0.360 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.640 0.360 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.640 0.360 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.640 0.360 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.640 0.360 0.000
M65-M68 Disorders of synovium and tendon
0.640 0.360 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.639 0.361 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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