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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs114987466
log Bayes Factor = 13.887
Chromosome 1   position 21,632,046  (GRCh37) Explore rs114987466 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Chapter II Neoplasms
0.999 0.001 0.000
D10-D36 Benign neoplasms
0.996 0.004 0.000
Chapter IX Diseases of the circulatory system
0.992 0.008 0.000
M05-M14 Inflammatory polyarthropathies
0.991 0.009 0.000
M50-M54 Other dorsopathies
0.991 0.009 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.988 0.012 0.000
M10 Gout
0.987 0.013 0.000
D23 Other benign neoplasms of skin
0.986 0.014 0.000
M10.9 Gout, unspecified
0.984 0.016 0.000
M10.99 Gout, unspecified (Site unspecified)
0.981 0.019 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.981 0.019 0.000
Chapter XX External causes of morbidity and mortality
0.980 0.020 0.000
Chapter I Certain infectious and parasitic diseases
0.974 0.026 0.000
I05-I09 Chronic rheumatic heart diseases
0.971 0.029 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.968 0.032 0.000
Chapter VI Diseases of the nervous system
0.964 0.036 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.954 0.046 0.000
Chapter XXI Factors influencing health status and contact with health services
0.953 0.047 0.000
D22 Melanocytic naevi
0.950 0.050 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.949 0.051 0.000
O48 Prolonged pregnancy
0.948 0.052 0.000
I30-I52 Other forms of heart disease
0.944 0.056 0.000
M54 Dorsalgia
0.944 0.056 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.939 0.061 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.934 0.066 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.934 0.066 0.000
D23.5 Skin of trunk
0.918 0.082 0.000
B95-B98 Bacterial, viral and other infectious agents
0.914 0.086 0.000
Z46 Fitting and adjustment of other devices
0.914 0.086 0.000
E70-E90 Metabolic disorders
0.904 0.096 0.000
Chapter VII Diseases of the eye and adnexa
0.901 0.099 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.901 0.099 0.000
M54.5 Low back pain
0.899 0.101 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.897 0.103 0.000
Chapter X Diseases of the respiratory system
0.896 0.104 0.000
M50 Cervical disk disorders
0.895 0.105 0.000
Z50 Care involving use of rehabilitation procedures
0.893 0.107 0.000
S32 Fracture of lumbar spine and pelvis
0.892 0.108 0.000
I07 Rheumatic tricuspid valve diseases
0.891 0.109 0.000
S70-S79 Injuries to the hip and thigh
0.890 0.110 0.000
E20-E35 Disorders of other endocrine glands
0.887 0.113 0.000
G90-G99 Other disorders of the nervous system
0.886 0.114 0.000
Chapter XXII Codes for special purposes
0.884 0.116 0.000
Z46.6 Fitting and adjustment of urinary device
0.884 0.116 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.883 0.117 0.000
M51 Other intervertebral disk disorders
0.882 0.118 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.879 0.121 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.877 0.123 0.000
D22.5 Melanocytic naevi of trunk
0.876 0.124 0.000
I60-I69 Cerebrovascular diseases
0.874 0.126 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.872 0.128 0.000
O60-O75 Complications of labour and delivery
0.872 0.128 0.000
D11 Benign neoplasm of major salivary glands
0.870 0.130 0.000
J20-J22 Other acute lower respiratory infections
0.870 0.130 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.866 0.134 0.000
I05 Rheumatic mitral valve diseases
0.866 0.134 0.000
D23.6 Skin of upper limb, including shoulder
0.865 0.135 0.000
I50 Heart failure
0.863 0.137 0.000
M54.56 Low back pain (Lumbar region)
0.863 0.137 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.860 0.140 0.000
Y43 Primarily systemic agents
0.857 0.143 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.855 0.145 0.000
I35 Nonrheumatic aortic valve disorders
0.855 0.145 0.000
G35 Multiple sclerosis
0.853 0.147 0.000
D23.1 Skin of eyelid, including canthus
0.850 0.150 0.000
J22 Unspecified acute lower respiratory infection
0.849 0.151 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.846 0.154 0.000
D10 Benign neoplasm of mouth and pharynx
0.845 0.155 0.000
S20-S29 Injuries to the thorax
0.845 0.155 0.000
S90-S99 Injuries to the ankle and foot
0.843 0.157 0.000
B35-B49 Mycoses
0.843 0.157 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.841 0.159 0.000
J90-J94 Other diseases of pleura
0.841 0.159 0.000
D23.4 Skin of scalp and neck
0.839 0.161 0.000
I08 Multiple valve diseases
0.837 0.163 0.000
M91-M94 Chondropathies
0.835 0.165 0.000
I07.1 Tricuspid insufficiency
0.834 0.166 0.000
W00-W19 Falls
0.834 0.166 0.000
Z40 Prophylactic surgery
0.833 0.167 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.831 0.169 0.000
D25 Leiomyoma of uterus
0.829 0.171 0.000
M10.97 Gout, unspecified (Ankle and foot)
0.823 0.177 0.000
I61 Intracerebral haemorrhage
0.820 0.180 0.000
O44 Placenta praevia
0.819 0.181 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.817 0.183 0.000
Z50.8 Care involving use of rehabilitation procedures
0.817 0.183 0.000
H04 Disorders of lachrymal system
0.816 0.184 0.000
M54.1 Radiculopathy
0.815 0.185 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.815 0.185 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.813 0.187 0.000
D22.3 Melanocytic naevi of other and unspecified parts of face
0.809 0.191 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.808 0.191 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.808 0.192 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.808 0.192 0.000
A30-A49 Other bacterial diseases
0.808 0.192 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.806 0.193 0.000
D25.9 Leiomyoma of uterus, unspecified
0.803 0.197 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.803 0.197 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.802 0.198 0.000
I60 Subarachnoid haemorrhage
0.800 0.200 0.000
S32.4 Fracture of acetabulum
0.799 0.201 0.000
I47 Paroxysmal tachycardia
0.799 0.201 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.798 0.202 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.797 0.203 0.000
D70 Agranulocytosis
0.797 0.203 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.795 0.205 0.000
M65-M68 Disorders of synovium and tendon
0.793 0.207 0.000
Z45 Adjustment and management of implanted device
0.791 0.209 0.000
I35.0 Aortic (valve) stenosis
0.790 0.210 0.000
O30 Multiple gestation
0.789 0.211 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.786 0.214 0.000
C79 Secondary malignant neoplasm of other sites
0.786 0.214 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.784 0.216 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.783 0.217 0.000
E10-E14 Diabetes mellitus
0.783 0.217 0.000
M06 Other rheumatoid arthritis
0.782 0.218 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.781 0.219 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.779 0.221 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.779 0.221 0.000
Y43.3 Other antineoplastic drugs
0.779 0.221 0.000
D11.0 Parotid gland
0.779 0.221 0.000
O63 Long labour
0.775 0.225 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.775 0.225 0.000
Y52 Agents primarily affecting the cardiovascular system
0.775 0.225 0.000
M51.2 Other specified intervertebral disk displacement
0.774 0.226 0.000
S80-S89 Injuries to the knee and lower leg
0.774 0.226 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.772 0.228 0.000
D22.4 Melanocytic naevi of scalp and neck
0.770 0.229 0.000
M40-M43 Deforming dorsopathies
0.770 0.230 0.000
Z50.1 Other physical therapy
0.770 0.230 0.000
D32 Benign neoplasm of meninges
0.769 0.231 0.000
G30-G32 Other degenerative diseases of the nervous system
0.769 0.231 0.000
E87.5 Hyperkalaemia
0.768 0.232 0.000
Z50.0 Cardiac rehabilitation
0.768 0.232 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.766 0.234 0.000
S10-S19 Injuries to the neck
0.762 0.238 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.761 0.239 0.000
W20-W49 Exposure to inanimate mechanical forces
0.761 0.239 0.000
I45 Other conduction disorders
0.759 0.241 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.758 0.242 0.000
I05.2 Mitral stenosis with insufficiency
0.756 0.244 0.000
D34 Benign neoplasm of thyroid gland
0.756 0.244 0.000
I50.9 Heart failure, unspecified
0.755 0.245 0.000
Z49 Care involving dialysis
0.755 0.245 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.752 0.248 0.000
H55-H59 Other disorders of eye and adnexa
0.752 0.248 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.751 0.249 0.000
D46 Myelodysplastic syndromes
0.750 0.250 0.000
S70 Superficial injury of hip and thigh
0.749 0.251 0.000
D23.2 Skin of ear and external auricular canal
0.748 0.252 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.747 0.253 0.000
O42 Premature rupture of membranes
0.746 0.253 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.746 0.254 0.000
M50.1 Cervical disk disorder with radiculopathy
0.745 0.255 0.000
C60-C63 Malignant neoplasms of male genital organs
0.745 0.255 0.000
D00-D09 In situ neoplasms
0.745 0.255 0.000
Chapter VIII Diseases of the ear and mastoid process
0.744 0.256 0.000
W50-W64 Exposure to animate mechanical forces
0.744 0.256 0.000
Z51 Other medical care
0.744 0.256 0.000
T79-T79 Certain early complications of trauma
0.744 0.256 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.743 0.257 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.743 0.257 0.000
H04.2 Epiphora
0.743 0.257 0.000
O43 Placental disorders
0.743 0.257 0.000
T66-T78 Other and unspecified effects of external causes
0.742 0.258 0.000
I47.1 Supraventricular tachycardia
0.741 0.259 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.741 0.259 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.741 0.259 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.735 0.265 0.000
O40 Polyhydramnios
0.735 0.265 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.735 0.265 0.000
O36 Maternal care for other known or suspected foetal problems
0.734 0.266 0.000
I63 Cerebral infarction
0.733 0.267 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.733 0.267 0.000
I51 Complications and ill-defined descriptions of heart disease
0.733 0.267 0.000
S32.40 Fracture of acetabulum (closed)
0.733 0.267 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.732 0.268 0.000
J95-J99 Other diseases of the respiratory system
0.732 0.268 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.732 0.268 0.000
I08.0 Disorders of both mitral and aortic valves
0.728 0.272 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.728 0.272 0.000
M80-M85 Disorders of bone density and structure
0.727 0.273 0.000
S92 Fracture of foot, except ankle
0.727 0.273 0.000
E28 Ovarian dysfunction
0.726 0.274 0.000
O32.1 Maternal care for breech presentation
0.726 0.274 0.000
D68 Other coagulation defects
0.725 0.275 0.000
D22.6 Melanocytic naevi of upper limb, including shoulder
0.724 0.276 0.000
Y44 Agents primarily affecting blood constituents
0.724 0.276 0.000
S32.3 Fracture of ilium
0.723 0.276 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.723 0.277 0.000
L20-L30 Dermatitis and eczema
0.723 0.277 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.722 0.278 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.722 0.278 0.000
A80-A89 Viral infections of the central nervous system
0.721 0.279 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.720 0.280 0.000
D10.3 Other and unspecified parts of mouth
0.720 0.280 0.000
Chapter XIV Diseases of the genitourinary system
0.720 0.280 0.000
M20-M25 Other joint disorders
0.719 0.280 0.000
M50.0 Cervical disk disorder with myelopathy
0.719 0.281 0.000
M94 Other disorders of cartilage
0.718 0.282 0.000
Z41 Procedures for purposes other than remedying health state
0.718 0.282 0.000
E88 Other metabolic disorders
0.717 0.282 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M50.3 Other cervical disk degeneration
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
T33-T35 Frostbite
0.716 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.716 0.284 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.284 0.000
Z45.2 Adjustment and management of vascular access device
0.716 0.284 0.000
M86-M90 Other osteopathies
0.715 0.285 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.715 0.285 0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms
0.715 0.285 0.000
D31 Benign neoplasm of eye and adnexa
0.714 0.286 0.000
D30 Benign neoplasm of urinary organs
0.714 0.286 0.000
D29 Benign neoplasm of male genital organs
0.714 0.286 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.714 0.286 0.000
D26 Other benign neoplasms of uterus
0.714 0.286 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.714 0.286 0.000
D19 Benign neoplasm of mesothelial tissue
0.714 0.286 0.000
D16 Benign neoplasm of bone and articular cartilage
0.714 0.286 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.714 0.286 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.714 0.286 0.000
M54.2 Cervicalgia
0.714 0.286 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.714 0.286 0.000
X60-X84 Intentional self-harm
0.714 0.286 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.714 0.286 0.000
T87 Complications peculiar to reattachment and amputation
0.712 0.287 0.000
W10 Fall on and from stairs and steps
0.712 0.288 0.000
M54.16 Radiculopathy (Lumbar region)
0.712 0.288 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.712 0.288 0.000
I00-I02 Acute rheumatic fever
0.711 0.289 0.000
V20-V29 Motorcycle rider injured in transport accident
0.711 0.289 0.000
V10-V19 Pedal cyclist injured in transport accident
0.710 0.289 0.000
M14 Arthropathies in other diseases classified elsewhere
0.710 0.290 0.000
M12 Other specific arthropathies
0.710 0.290 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.710 0.290 0.000
M08 Juvenile arthritis
0.710 0.290 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.710 0.290 0.000
E22 Hyperfunction of pituitary gland
0.709 0.290 0.000
J92 Pleural plaque
0.709 0.291 0.000
M05 Seropositive rheumatoid arthritis
0.709 0.291 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.709 0.291 0.000
G96 Other disorders of central nervous system
0.708 0.292 0.000
S29 Other and unspecified injuries of thorax
0.708 0.292 0.000
O85-O92 Complications predominantly related to the puerperium
0.708 0.292 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.708 0.292 0.000
M10.4 Other secondary gout
0.708 0.292 0.000
M10.3 Gout due to impairment of renal function
0.708 0.292 0.000
M10.2 Drug-induced gout
0.708 0.292 0.000
M10.1 Lead-induced gout
0.708 0.292 0.000
M10.0 Idiopathic gout
0.708 0.292 0.000
I05.0 Mitral stenosis
0.708 0.292 0.000
D23.9 Skin, unspecified
0.707 0.293 0.000
D23.0 Skin of lip
0.707 0.293 0.000
I34 Nonrheumatic mitral valve disorders
0.706 0.294 0.000
O47 False labour
0.706 0.294 0.000
M10.98 Gout, unspecified (Other)
0.706 0.294 0.000
M10.96 Gout, unspecified (Lower leg)
0.706 0.294 0.000
M10.95 Gout, unspecified (Pelvic region and thigh)
0.706 0.294 0.000
M10.94 Gout, unspecified (Hand)
0.706 0.294 0.000
M10.93 Gout, unspecified (Forearm)
0.706 0.294 0.000
M10.92 Gout, unspecified (Upper arm)
0.706 0.294 0.000
M10.91 Gout, unspecified (Shoulder region)
0.706 0.294 0.000
M10.90 Gout, unspecified (Multiple sites)
0.706 0.294 0.000
E40-E46 Malnutrition
0.705 0.295 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.705 0.295 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.705 0.295 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.705 0.295 0.000
T81 Complications of procedures, not elsewhere classified
0.705 0.295 0.000
O41 Other disorders of amniotic fluid and membranes
0.704 0.296 0.000
D27 Benign neoplasm of ovary
0.704 0.296 0.000
S32.0 Fracture of lumbar vertebra
0.704 0.296 0.000
O45 Premature separation of placenta [abruptio placentae]
0.703 0.297 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.703 0.297 0.000
O33 Maternal care for known or suspected disproportion
0.703 0.297 0.000
O31 Complications specific to multiple gestation
0.703 0.297 0.000
I50.1 Left ventricular failure
0.703 0.297 0.000
Y35-Y36 Legal intervention and operations of war
0.703 0.297 0.000
Y10-Y34 Event of undetermined intent
0.703 0.297 0.000
Y00-Y09 Assault
0.703 0.297 0.000
X85-X99 Assault
0.703 0.297 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.703 0.297 0.000
X50-X57 Overexertion, travel and privation
0.703 0.297 0.000
X30-X39 Exposure to forces of nature
0.703 0.297 0.000
X20-X29 Contact with venomous animals and plants
0.703 0.297 0.000
X10-X19 Contact with heat and hot substances
0.703 0.297 0.000
X00-X09 Exposure to smoke, fire and flames
0.703 0.297 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.703 0.297 0.000
W75-W84 Other accidental threats to breathing
0.703 0.297 0.000
W65-W74 Accidental drowning and submersion
0.703 0.297 0.000
V98-V99 Other and unspecified transport accidents
0.703 0.297 0.000
V95-V97 Air and space transport accidents
0.703 0.297 0.000
V90-V94 Water transport accidents
0.703 0.297 0.000
V80-V89 Other land transport accidents
0.703 0.297 0.000
V70-V79 Bus occupant injured in transport accident
0.703 0.297 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.703 0.297 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.703 0.297 0.000
V40-V49 Car occupant injured in transport accident
0.703 0.297 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.703 0.297 0.000
V01-V09 Pedestrian injured in transport accident
0.703 0.297 0.000
M53 Other dorsopathies, not elsewhere classified
0.702 0.298 0.000
D72 Other disorders of white blood cells
0.702 0.298 0.000
E11 Non-insulin-dependent diabetes mellitus
0.702 0.298 0.000
M51.9 Intervertebral disk disorder, unspecified
0.701 0.299 0.000
Chapter XI Diseases of the digestive system
0.700 0.300 0.000
K90-K93 Other diseases of the digestive system
0.699 0.301 0.000
D23.3 Skin of other and unspecified parts of face
0.699 0.301 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.699 0.301 0.000
B99-B99 Other infectious diseases
0.698 0.302 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.698 0.302 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.698 0.302 0.000
B65-B83 Helminthiases
0.698 0.302 0.000
B50-B64 Protozoal diseases
0.698 0.302 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.698 0.302 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.698 0.302 0.000
A75-A79 Rickettsioses
0.698 0.302 0.000
A70-A74 Other diseases caused by chlamydiae
0.698 0.302 0.000
A65-A69 Other spirochaetal diseases
0.698 0.302 0.000
A20-A28 Certain zoonotic bacterial diseases
0.698 0.302 0.000
A15-A19 Tuberculosis
0.698 0.302 0.000
E50-E64 Other nutritional deficiencies
0.698 0.302 0.000
Y40 Systemic antibiotics
0.698 0.302 0.000
Z46.8 Fitting and adjustment of other specified devices
0.697 0.302 0.000
G20-G26 Extrapyramidal and movement disorders
0.697 0.303 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.697 0.303 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.697 0.303 0.000
I09 Other rheumatic heart diseases
0.696 0.303 0.000
I06 Rheumatic aortic valve diseases
0.696 0.303 0.000
M54.57 Low back pain (Lumbosacral region)
0.696 0.304 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.696 0.304 0.000
E26 Hyperaldosteronism
0.695 0.305 0.000
K92 Other diseases of digestive system
0.694 0.306 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.691 0.309 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.691 0.309 0.000
Z48 Other surgical follow-up care
0.691 0.309 0.000
S72 Fracture of femur
0.691 0.309 0.000
B35 Dermatophytosis
0.690 0.310 0.000
C92 Myeloid leukaemia
0.689 0.311 0.000
H00 Hordeolum and chalazion
0.688 0.311 0.000
L29 Pruritus
0.688 0.312 0.000
G70-G73 Diseases of myoneural junction and muscle
0.688 0.312 0.000
M07 Psoriatic and enteropathic arthropathies
0.688 0.312 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.688 0.312 0.000
Y43.4 Immunosuppressive agents
0.687 0.313 0.000
D80-D89 Certain disorders involving the immune mechanism
0.687 0.313 0.000
I10-I15 Hypertensive diseases
0.687 0.313 0.000
J94 Other pleural conditions
0.686 0.313 0.000
E23 Hypofunction and other disorders of pituitary gland
0.686 0.314 0.000
S71 Open wound of hip and thigh
0.685 0.315 0.000
G95 Other diseases of spinal cord
0.685 0.315 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.684 0.316 0.000
S37 Injury of urinary and pelvic organs
0.684 0.316 0.000
S36 Injury of intra-abdominal organs
0.684 0.316 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.684 0.316 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.684 0.316 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.684 0.316 0.000
S31 Open wound of abdomen, lower back and pelvis
0.684 0.316 0.000
A41 Other septicaemia
0.684 0.316 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.684 0.316 0.000
J93 Pneumothorax
0.684 0.316 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.684 0.316 0.000
O63.1 Prolonged second stage (of labour)
0.683 0.317 0.000
K92.1 Melaena
0.682 0.318 0.000
B37 Candidiasis
0.682 0.318 0.000
D22.9 Melanocytic naevi, unspecified
0.681 0.319 0.000
D22.2 Melanocytic naevi of ear and external auricular canal
0.681 0.319 0.000
D22.1 Melanocytic naevi of eyelid, including canthus
0.681 0.319 0.000
D22.0 Melanocytic naevi of lip
0.681 0.319 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.681 0.319 0.000
Z54 Convalescence
0.680 0.320 0.000
Z44 Fitting and adjustment of external prosthetic device
0.680 0.320 0.000
W18 Other fall on same level
0.680 0.320 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.680 0.320 0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.680 0.320 0.000
C71 Malignant neoplasm of brain
0.679 0.321 0.000
D23.7 Skin of lower limb, including hip
0.679 0.321 0.000
B97.8 Other viral agents as the cause of diseases classified to other chapters
0.679 0.321 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.679 0.321 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.678 0.322 0.000
I52 Other heart disorders in diseases classified elsewhere
0.677 0.323 0.000
I48 Atrial fibrillation and flutter
0.677 0.323 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.677 0.323 0.000
I41 Myocarditis in diseases classified elsewhere
0.677 0.323 0.000
I40 Acute myocarditis
0.677 0.323 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.677 0.323 0.000
I37 Pulmonary valve disorders
0.677 0.323 0.000
I36 Nonrheumatic tricuspid valve disorders
0.677 0.323 0.000
I32 Pericarditis in diseases classified elsewhere
0.677 0.323 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.677 0.323 0.000
M54.8 Other dorsalgia
0.677 0.323 0.000
M54.6 Pain in thoracic spine
0.677 0.323 0.000
M54.0 Panniculitis affecting regions of neck and back
0.677 0.323 0.000
J90 Pleural effusion, not elsewhere classified
0.676 0.324 0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.674 0.325 0.000
M51.8 Other specified intervertebral disk disorders
0.673 0.326 0.000
D55-D59 Haemolytic anaemias
0.673 0.327 0.000
C80 Malignant neoplasm without specification of site
0.672 0.328 0.000
C09 Malignant neoplasm of tonsil
0.672 0.328 0.000
M54.50 Low back pain (Multiple sites in spine)
0.671 0.329 0.000
G03 Meningitis due to other and unspecified causes
0.671 0.329 0.000
S79 Other and unspecified injuries of hip and thigh
0.671 0.329 0.000
C45 Mesothelioma
0.671 0.329 0.000
Y59 Other and unspecified vaccines and biological substances
0.670 0.330 0.000
Y58 Bacterial vaccines
0.670 0.330 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.670 0.330 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.670 0.330 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.670 0.330 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.670 0.330 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.670 0.330 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.670 0.330 0.000
Y48 Anaesthetics and therapeutic gases
0.670 0.330 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.670 0.330 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.670 0.330 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.670 0.330 0.000
I61.5 Intracerebral haemorrhage, intraventricular
0.670 0.330 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.669 0.330 0.000
S32.7 Multiple fractures of lumbar spine and pelvis
0.669 0.330 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.669 0.331 0.000
O63.9 Long labour, unspecified
0.669 0.331 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.669 0.331 0.000
T51 Toxic effect of alcohol
0.668 0.332 0.000
Z40.8 Other prophylactic surgery
0.668 0.332 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.667 0.332 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.667 0.333 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.666 0.333 0.000
C81 Hodgkin's disease
0.666 0.334 0.000
Z51.5 Palliative care
0.666 0.334 0.000
B15-B19 Viral hepatitis
0.666 0.334 0.000
O44.1 Placenta praevia with haemorrhage
0.665 0.335 0.000
D24 Benign neoplasm of breast
0.665 0.335 0.000
M11 Other crystal arthropathies
0.665 0.335 0.000
I30 Acute pericarditis
0.664 0.335 0.000
M25 Other joint disorders, not elsewhere classified
0.663 0.337 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.663 0.337 0.000
T31 Burns classified according to extent of body surface involved
0.663 0.337 0.000
I50.0 Congestive heart failure
0.661 0.338 0.000
G37 Other demyelinating diseases of central nervous system
0.661 0.339 0.000
T86 Failure and rejection of transplanted organs and tissues
0.660 0.340 0.000
M54.59 Low back pain (Site unspecified)
0.660 0.340 0.000
S70.0 Contusion of hip
0.660 0.340 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.659 0.341 0.000
E87.0 Hyperosmolality and hypernatraemia
0.659 0.341 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.658 0.342 0.000
E78.5 Hyperlipidaemia, unspecified
0.657 0.343 0.000
I33 Acute and subacute endocarditis
0.657 0.343 0.000
S40-S49 Injuries to the shoulder and upper arm
0.656 0.344 0.000
N10-N16 Renal tubulo-interstitial diseases
0.656 0.344 0.000
D14.0 Middle ear, nasal cavity and accessory sinuses
0.655 0.345 0.000
Z46.9 Fitting and adjustment of other unspecified device
0.655 0.345 0.000
Z46.7 Fitting and adjustment of orthopaedic device
0.655 0.345 0.000
Z46.5 Fitting and adjustment of ileostomy and other intestinal appliances
0.655 0.345 0.000
Z46.4 Fitting and adjustment of orthodontic device
0.655 0.345 0.000
Z46.3 Fitting and adjustment of dental prosthetic device
0.655 0.345 0.000
Z46.2 Fitting and adjustment of other devices related to nervous system and special senses
0.655 0.345 0.000
Z46.1 Fitting and adjustment of hearing aid
0.655 0.345 0.000
Z46.0 Fitting and adjustment of spectacles and contact lenses
0.655 0.345 0.000
D46.9 Myelodysplastic syndrome, unspecified
0.655 0.345 0.000
O32.0 Maternal care for unstable lie
0.655 0.345 0.000
M50.2 Other cervical disk displacement
0.654 0.346 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.654 0.346 0.000
H40-H42 Glaucoma
0.653 0.347 0.000
B25-B34 Other viral diseases
0.653 0.347 0.000
Z51.1 Chemotherapy session for neoplasm
0.653 0.347 0.000
D60-D64 Aplastic and other anaemias
0.652 0.348 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.652 0.348 0.000
I49 Other cardiac arrhythmias
0.652 0.348 0.000
H18 Other disorders of cornea
0.652 0.348 0.000
O30.0 Twin pregnancy
0.651 0.349 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.651 0.349 0.000
H43-H45 Disorders of vitreous body and globe
0.651 0.349 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.650 0.350 0.000
Y57 Other and unspecified drugs and medicaments
0.650 0.350 0.000
O80-O84 Delivery
0.649 0.351 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.649 0.351 0.000
C83.3 Large cell (diffuse)
0.649 0.351 0.000
E85 Amyloidosis
0.648 0.352 0.000
E84 Cystic fibrosis
0.648 0.352 0.000
E79 Disorders of purine and pyrimidine metabolism
0.648 0.352 0.000
E77 Disorders of glycoprotein metabolism
0.648 0.352 0.000
E76 Disorders of glycosaminoglycan metabolism
0.648 0.352 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.648 0.352 0.000
E74 Other disorders of carbohydrate metabolism
0.648 0.352 0.000
E73 Lactose intolerance
0.648 0.352 0.000
E72 Other disorders of amino-acid metabolism
0.648 0.352 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.648 0.352 0.000
E70 Disorders of aromatic amino-acid metabolism
0.648 0.352 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.648 0.352 0.000
D18 Haemangioma and lymphangioma, any site
0.646 0.354 0.000
E16 Other disorders of pancreatic internal secretion
0.646 0.354 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.646 0.354 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.646 0.354 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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