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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117549422
log Bayes Factor = 15.8527
Chromosome 19   position 3,415,481  (GRCh37) Explore rs117549422 on Ensembl!
Variant rs117549422 is part of Cluster X0181

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
M45-M49 Spondylopathies
0.998 0.002 0.000
M05-M14 Inflammatory polyarthropathies
0.997 0.003 0.000
M47 Spondylosis
0.997 0.003 0.000
M20-M25 Other joint disorders
0.995 0.005 0.000
M47.9 Spondylosis, unspecified
0.995 0.005 0.000
Chapter XXI Factors influencing health status and contact with health services
0.995 0.005 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.988 0.012 0.000
E65-E68 Obesity and other hyperalimentation
0.988 0.012 0.000
Z50 Care involving use of rehabilitation procedures
0.985 0.015 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.985 0.015 0.000
Chapter XX External causes of morbidity and mortality
0.984 0.016 0.000
E66 Obesity
0.979 0.021 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.977 0.023 0.000
Chapter IX Diseases of the circulatory system
0.977 0.023 0.000
Chapter I Certain infectious and parasitic diseases
0.977 0.023 0.000
Z50.1 Other physical therapy
0.977 0.023 0.000
M13 Other arthritis
0.975 0.025 0.000
Chapter VIII Diseases of the ear and mastoid process
0.974 0.026 0.000
M25 Other joint disorders, not elsewhere classified
0.974 0.026 0.000
M25.5 Pain in joint
0.967 0.033 0.000
M23 Internal derangement of knee
0.964 0.036 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.963 0.037 0.000
Chapter VI Diseases of the nervous system
0.959 0.041 0.000
M13.9 Arthritis, unspecified
0.956 0.044 0.000
E66.9 Obesity, unspecified
0.955 0.045 0.000
Chapter V Mental and behavioural disorders
0.953 0.047 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.952 0.048 0.000
I60-I69 Cerebrovascular diseases
0.950 0.050 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.949 0.051 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.948 0.052 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.948 0.052 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.945 0.055 0.000
E20-E35 Disorders of other endocrine glands
0.944 0.056 0.000
F30-F39 Mood [affective] disorders
0.940 0.060 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.940 0.060 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.938 0.062 0.000
Z09.9 Follow-up examination after unspecified treatment for other conditions
0.936 0.064 0.000
M10 Gout
0.932 0.068 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.932 0.068 0.000
I05-I09 Chronic rheumatic heart diseases
0.932 0.068 0.000
E70-E90 Metabolic disorders
0.925 0.075 0.000
H65-H75 Diseases of middle ear and mastoid
0.918 0.082 0.000
G40-G47 Episodic and paroxysmal disorders
0.916 0.084 0.000
M70-M79 Other soft tissue disorders
0.911 0.089 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.911 0.089 0.000
E66.8 Other obesity
0.911 0.089 0.000
M50-M54 Other dorsopathies
0.910 0.090 0.000
Chapter VII Diseases of the eye and adnexa
0.909 0.091 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.907 0.093 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.907 0.093 0.000
A30-A49 Other bacterial diseases
0.907 0.093 0.000
S40-S49 Injuries to the shoulder and upper arm
0.904 0.096 0.000
E87.6 Hypokalaemia
0.904 0.096 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.901 0.099 0.000
Z03.4 Observation for suspected myocardial infarction
0.899 0.101 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.898 0.102 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.898 0.102 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.896 0.104 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.893 0.107 0.000
B95-B98 Bacterial, viral and other infectious agents
0.893 0.107 0.000
G40 Epilepsy
0.893 0.107 0.000
F33 Recurrent depressive disorder
0.890 0.110 0.000
I73 Other peripheral vascular diseases
0.888 0.112 0.000
I08 Multiple valve diseases
0.888 0.112 0.000
M10.9 Gout, unspecified
0.886 0.114 0.000
M25.51 Pain in joint (Shoulder region)
0.879 0.121 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.879 0.121 0.000
F31 Bipolar affective disorder
0.871 0.129 0.000
Z41 Procedures for purposes other than remedying health state
0.870 0.130 0.000
M47.8 Other spondylosis
0.865 0.135 0.000
G90-G99 Other disorders of the nervous system
0.864 0.136 0.000
M40-M43 Deforming dorsopathies
0.864 0.136 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.862 0.138 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.861 0.139 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.860 0.140 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.857 0.143 0.000
M10.99 Gout, unspecified (Site unspecified)
0.853 0.147 0.000
F33.9 Recurrent depressive disorder, unspecified
0.853 0.147 0.000
H04 Disorders of lachrymal system
0.852 0.148 0.000
G40.9 Epilepsy, unspecified
0.851 0.149 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.851 0.149 0.000
M21 Other acquired deformities of limbs
0.850 0.150 0.000
E10-E14 Diabetes mellitus
0.850 0.150 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.847 0.153 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.846 0.154 0.000
M86-M90 Other osteopathies
0.845 0.155 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.841 0.159 0.000
I71 Aortic aneurysm and dissection
0.840 0.160 0.000
M06 Other rheumatoid arthritis
0.838 0.162 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.837 0.163 0.000
A41 Other septicaemia
0.834 0.166 0.000
E27 Other disorders of adrenal gland
0.834 0.166 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.831 0.169 0.000
M51 Other intervertebral disk disorders
0.828 0.172 0.000
H02 Other disorders of eyelid
0.825 0.175 0.000
T92 Sequelae of injuries of upper limb
0.824 0.176 0.000
Z09.2 Follow-up examination after chemotherapy for other conditions
0.824 0.176 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.822 0.178 0.000
G30-G32 Other degenerative diseases of the nervous system
0.821 0.179 0.000
H04.2 Epiphora
0.821 0.179 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.820 0.180 0.000
I69 Sequelae of cerebrovascular disease
0.818 0.182 0.000
Y85 Sequelae of transport accidents
0.815 0.185 0.000
I63 Cerebral infarction
0.814 0.186 0.000
I73.9 Peripheral vascular disease, unspecified
0.813 0.187 0.000
M25.56 Pain in joint (Lower leg)
0.811 0.189 0.000
H80-H83 Diseases of inner ear
0.810 0.190 0.000
E23 Hypofunction and other disorders of pituitary gland
0.810 0.190 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.809 0.191 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.808 0.192 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.807 0.193 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.807 0.193 0.000
S70-S79 Injuries to the hip and thigh
0.807 0.193 0.000
X60-X84 Intentional self-harm
0.806 0.194 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.805 0.195 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.805 0.195 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.802 0.198 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.802 0.198 0.000
M25.50 Pain in joint (Multiple sites)
0.799 0.201 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.798 0.202 0.000
Z50.8 Care involving use of rehabilitation procedures
0.797 0.203 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.797 0.203 0.000
Z44 Fitting and adjustment of external prosthetic device
0.797 0.203 0.000
M91-M94 Chondropathies
0.796 0.204 0.000
Z49 Care involving dialysis
0.795 0.205 0.000
M25.54 Pain in joint (Hand)
0.794 0.205 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.794 0.206 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.792 0.208 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.791 0.208 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.790 0.210 0.000
H90-H95 Other disorders of ear
0.789 0.211 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.789 0.211 0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance
0.788 0.212 0.000
Z03.6 Observation for suspected toxic effect from ingested substance
0.786 0.214 0.000
M25.57 Pain in joint (Ankle and foot)
0.784 0.216 0.000
Z50.5 Speech therapy
0.784 0.216 0.000
M47.86 Other spondylosis (Lumbar region)
0.784 0.216 0.000
A80-A89 Viral infections of the central nervous system
0.782 0.218 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.780 0.220 0.000
M24 Other specific joint derangements
0.780 0.220 0.000
M46 Other inflammatory spondylopathies
0.779 0.221 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.777 0.223 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.775 0.225 0.000
E14 Unspecified diabetes mellitus
0.775 0.225 0.000
Z09.8 Follow-up examination after other treatment for other conditions
0.774 0.226 0.000
T81 Complications of procedures, not elsewhere classified
0.774 0.226 0.000
G44 Other headache syndromes
0.773 0.227 0.000
I67 Other cerebrovascular diseases
0.773 0.227 0.000
S10-S19 Injuries to the neck
0.771 0.229 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.770 0.230 0.000
M07 Psoriatic and enteropathic arthropathies
0.770 0.230 0.000
I77 Other disorders of arteries and arterioles
0.768 0.232 0.000
I05 Rheumatic mitral valve diseases
0.768 0.232 0.000
S60-S69 Injuries to the wrist and hand
0.767 0.233 0.000
B99-B99 Other infectious diseases
0.765 0.235 0.000
S20-S29 Injuries to the thorax
0.764 0.236 0.000
S80-S89 Injuries to the knee and lower leg
0.764 0.236 0.000
E24 Cushing's syndrome
0.763 0.237 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.763 0.237 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.762 0.238 0.000
E50-E64 Other nutritional deficiencies
0.762 0.238 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.761 0.239 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.761 0.239 0.000
V40-V49 Car occupant injured in transport accident
0.761 0.239 0.000
S50-S59 Injuries to the elbow and forearm
0.760 0.240 0.000
X50-X57 Overexertion, travel and privation
0.758 0.242 0.000
H71 Cholesteatoma of middle ear
0.757 0.243 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.757 0.243 0.000
H02.3 Blepharochalasis
0.755 0.245 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.755 0.245 0.000
I60 Subarachnoid haemorrhage
0.755 0.245 0.000
M25.59 Pain in joint (Site unspecified)
0.753 0.247 0.000
H65 Nonsuppurative otitis media
0.752 0.248 0.000
H74 Other disorders of middle ear and mastoid
0.752 0.248 0.000
F32 Depressive episode
0.750 0.250 0.000
M25.53 Pain in joint (Forearm)
0.750 0.250 0.000
H02.0 Entropion and trichiasis of eyelid
0.750 0.250 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.749 0.251 0.000
Z47 Other orthopaedic follow-up care
0.749 0.251 0.000
Z42 Follow-up care involving plastic surgery
0.749 0.251 0.000
H60-H62 Diseases of external ear
0.748 0.252 0.000
M13.0 Polyarthritis, unspecified
0.747 0.253 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.747 0.253 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.747 0.253 0.000
G93 Other disorders of brain
0.746 0.254 0.000
M43 Other deforming dorsopathies
0.745 0.255 0.000
I73.0 Raynaud's syndrome
0.745 0.255 0.000
M13.98 Arthritis, unspecified (Other)
0.744 0.255 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.744 0.256 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.743 0.257 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.742 0.258 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.742 0.258 0.000
W20-W49 Exposure to inanimate mechanical forces
0.741 0.259 0.000
Z54 Convalescence
0.741 0.259 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.741 0.259 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.739 0.261 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.739 0.261 0.000
A39 Meningococcal infection
0.739 0.261 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.738 0.262 0.000
V80-V89 Other land transport accidents
0.738 0.262 0.000
H72 Perforation of tympanic membrane
0.737 0.263 0.000
F60-F69 Disorders of adult personality and behaviour
0.737 0.263 0.000
L60-L75 Disorders of skin appendages
0.736 0.264 0.000
M47.2 Other spondylosis with radiculopathy
0.735 0.264 0.000
M80-M85 Disorders of bone density and structure
0.734 0.266 0.000
Y85.0 Sequelae of motor-vehicle accident
0.733 0.267 0.000
A41.8 Other specified septicaemia
0.733 0.267 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.733 0.267 0.000
M05 Seropositive rheumatoid arthritis
0.732 0.267 0.000
B25-B34 Other viral diseases
0.732 0.268 0.000
F20 Schizophrenia
0.732 0.268 0.000
M65-M68 Disorders of synovium and tendon
0.731 0.269 0.000
M06.9 Rheumatoid arthritis, unspecified
0.731 0.269 0.000
E22 Hyperfunction of pituitary gland
0.730 0.270 0.000
S43.0 Dislocation of shoulder joint
0.730 0.270 0.000
E78.5 Hyperlipidaemia, unspecified
0.728 0.272 0.000
W00-W19 Falls
0.727 0.272 0.000
M11 Other crystal arthropathies
0.725 0.274 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.725 0.275 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.725 0.275 0.000
T92.1 Sequelae of fracture of arm
0.725 0.275 0.000
Y86 Sequelae of other accidents
0.724 0.276 0.000
E14.9 Without complications
0.723 0.277 0.000
I69.3 Sequelae of cerebral infarction
0.723 0.277 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.722 0.277 0.000
I78 Diseases of capillaries
0.720 0.280 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.720 0.280 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.719 0.281 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.718 0.281 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.717 0.282 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
G95 Other diseases of spinal cord
0.717 0.283 0.000
E40-E46 Malnutrition
0.716 0.283 0.000
M49 Spondylopathies in diseases classified elsewhere
0.716 0.284 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.715 0.285 0.000
M14 Arthropathies in other diseases classified elsewhere
0.715 0.285 0.000
M12 Other specific arthropathies
0.715 0.285 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.715 0.285 0.000
M08 Juvenile arthritis
0.715 0.285 0.000
M47.1 Other spondylosis with myelopathy
0.715 0.285 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.715 0.285 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.714 0.286 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.714 0.286 0.000
M34 Systemic sclerosis
0.714 0.286 0.000
M33 Dermatopolymyositis
0.714 0.286 0.000
M32 Systemic lupus erythematosus
0.714 0.286 0.000
M30 Polyarteritis nodosa and related conditions
0.714 0.286 0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)
0.714 0.286 0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)
0.714 0.286 0.000
M47.94 Spondylosis, unspecified (Thoracic region)
0.714 0.286 0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)
0.714 0.286 0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)
0.714 0.286 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.713 0.286 0.000
M35 Other systemic involvement of connective tissue
0.713 0.286 0.000
E23.0 Hypopituitarism
0.713 0.287 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.713 0.287 0.000
T91 Sequelae of injuries of neck and trunk
0.713 0.287 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.713 0.287 0.000
Z50.2 Alcohol rehabilitation
0.712 0.288 0.000
T87 Complications peculiar to reattachment and amputation
0.709 0.291 0.000
T86 Failure and rejection of transplanted organs and tissues
0.709 0.291 0.000
E67 Other hyperalimentation
0.708 0.292 0.000
E68 Sequelae of hyperalimentation
0.708 0.292 0.000
E65 Localised adiposity
0.708 0.292 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.707 0.293 0.000
Z50.6 Orthoptic training
0.706 0.293 0.000
Z50.3 Drug rehabilitation
0.706 0.293 0.000
Z52 Donors of organs and tissues
0.706 0.294 0.000
H69 Other disorders of Eustachian tube
0.706 0.294 0.000
B35-B49 Mycoses
0.705 0.294 0.000
Y35-Y36 Legal intervention and operations of war
0.705 0.295 0.000
Y10-Y34 Event of undetermined intent
0.705 0.295 0.000
Y00-Y09 Assault
0.705 0.295 0.000
X85-X99 Assault
0.705 0.295 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.705 0.295 0.000
X30-X39 Exposure to forces of nature
0.705 0.295 0.000
X20-X29 Contact with venomous animals and plants
0.705 0.295 0.000
X10-X19 Contact with heat and hot substances
0.705 0.295 0.000
X00-X09 Exposure to smoke, fire and flames
0.705 0.295 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.705 0.295 0.000
W75-W84 Other accidental threats to breathing
0.705 0.295 0.000
W65-W74 Accidental drowning and submersion
0.705 0.295 0.000
W50-W64 Exposure to animate mechanical forces
0.705 0.295 0.000
V98-V99 Other and unspecified transport accidents
0.705 0.295 0.000
V95-V97 Air and space transport accidents
0.705 0.295 0.000
V90-V94 Water transport accidents
0.705 0.295 0.000
V70-V79 Bus occupant injured in transport accident
0.705 0.295 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.705 0.295 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.705 0.295 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.705 0.295 0.000
V01-V09 Pedestrian injured in transport accident
0.705 0.295 0.000
I65.2 Occlusion and stenosis of carotid artery
0.705 0.295 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.704 0.296 0.000
M79.6 Pain in limb
0.704 0.296 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.703 0.297 0.000
M77 Other enthesopathies
0.703 0.297 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.702 0.298 0.000
F99-F99 Unspecified mental disorder
0.702 0.298 0.000
F22 Persistent delusional disorders
0.702 0.298 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.702 0.298 0.000
E66.1 Drug-induced obesity
0.702 0.298 0.000
E66.0 Obesity due to excess calories
0.702 0.298 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.701 0.298 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.701 0.299 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.701 0.299 0.000
Z10 Routine general health check-up of defined subpopulation
0.701 0.299 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.701 0.299 0.000
I00-I02 Acute rheumatic fever
0.701 0.299 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.700 0.300 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.700 0.300 0.000
B65-B83 Helminthiases
0.700 0.300 0.000
B50-B64 Protozoal diseases
0.700 0.300 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.700 0.300 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.700 0.300 0.000
A75-A79 Rickettsioses
0.700 0.300 0.000
A70-A74 Other diseases caused by chlamydiae
0.700 0.300 0.000
A65-A69 Other spirochaetal diseases
0.700 0.300 0.000
A20-A28 Certain zoonotic bacterial diseases
0.700 0.300 0.000
A15-A19 Tuberculosis
0.700 0.300 0.000
M13.8 Other specified arthritis
0.699 0.301 0.000
M13.1 Monoarthritis, not elsewhere classified
0.699 0.301 0.000
H10-H13 Disorders of conjunctiva
0.699 0.301 0.000
M25.9 Joint disorder, unspecified
0.698 0.302 0.000
M25.3 Other instability of joint
0.698 0.302 0.000
M25.2 Flail joint
0.698 0.302 0.000
M25.1 Fistula of joint
0.698 0.302 0.000
M25.0 Haemarthrosis
0.698 0.302 0.000
T39.0 Salicylates
0.698 0.302 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.698 0.302 0.000
H83 Other diseases of inner ear
0.697 0.302 0.000
T66-T78 Other and unspecified effects of external causes
0.697 0.302 0.000
M79.1 Myalgia
0.697 0.303 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.695 0.305 0.000
Chapter XXII Codes for special purposes
0.694 0.306 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.694 0.306 0.000
E87.3 Alkalosis
0.694 0.306 0.000
T90 Sequelae of injuries of head
0.694 0.306 0.000
M54 Dorsalgia
0.694 0.306 0.000
M25.58 Pain in joint (Other)
0.694 0.306 0.000
M25.52 Pain in joint (Upper arm)
0.694 0.306 0.000
M53 Other dorsopathies, not elsewhere classified
0.694 0.306 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.693 0.307 0.000
M23.9 Internal derangement of knee, unspecified
0.691 0.309 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.691 0.309 0.000
M23.5 Chronic instability of knee
0.691 0.309 0.000
M23.1 Discoid meniscus (congenital)
0.691 0.309 0.000
M23.0 Cystic meniscus
0.691 0.309 0.000
G70-G73 Diseases of myoneural junction and muscle
0.691 0.309 0.000
E29 Testicular dysfunction
0.691 0.309 0.000
Z09.7 Follow-up examination after combined treatment for other conditions
0.690 0.309 0.000
Z09.4 Follow-up examination after treatment of fracture
0.690 0.309 0.000
Z09.3 Follow-up examination after psychotherapy
0.690 0.309 0.000
Z09.1 Follow-up examination after radiotherapy for other conditions
0.690 0.309 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.690 0.310 0.000
Z74 Problems related to care-provider dependency
0.690 0.310 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.688 0.312 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.686 0.314 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.686 0.314 0.000
M13.93 Arthritis, unspecified (Forearm)
0.686 0.314 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.686 0.314 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.686 0.314 0.000
I08.0 Disorders of both mitral and aortic valves
0.686 0.314 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.685 0.315 0.000
S42 Fracture of shoulder and upper arm
0.684 0.316 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.683 0.317 0.000
F70-F79 Mental retardation
0.683 0.317 0.000
H01 Other inflammation of eyelid
0.683 0.317 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.682 0.317 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.682 0.317 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.682 0.317 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.682 0.317 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.682 0.317 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.682 0.317 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.682 0.317 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.682 0.317 0.000
T36 Poisoning by systemic antibiotics
0.682 0.317 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.682 0.318 0.000
M25.8 Other specified joint disorders
0.682 0.318 0.000
Y52 Agents primarily affecting the cardiovascular system
0.681 0.319 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.681 0.319 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.681 0.319 0.000
B15-B19 Viral hepatitis
0.681 0.319 0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular
0.681 0.319 0.000
E28 Ovarian dysfunction
0.681 0.319 0.000
S00-S09 Injuries to the head
0.680 0.320 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.680 0.320 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.679 0.321 0.000
M48 Other spondylopathies
0.679 0.321 0.000
T92.2 Sequelae of fracture at wrist and hand level
0.679 0.321 0.000
V20-V29 Motorcycle rider injured in transport accident
0.678 0.322 0.000
F80-F89 Disorders of psychological development
0.678 0.322 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.678 0.322 0.000
T79-T79 Certain early complications of trauma
0.677 0.322 0.000
H04.3 Acute and unspecified inflammation of lachrymal passages
0.677 0.323 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.677 0.323 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.677 0.323 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.677 0.323 0.000
E34 Other endocrine disorders
0.677 0.323 0.000
E32 Diseases of thymus
0.677 0.323 0.000
E31 Polyglandular dysfunction
0.677 0.323 0.000
E30 Disorders of puberty, not elsewhere classified
0.677 0.323 0.000
E26 Hyperaldosteronism
0.677 0.323 0.000
E25 Adrenogenital disorders
0.677 0.323 0.000
E20 Hypoparathyroidism
0.677 0.323 0.000
Y57 Other and unspecified drugs and medicaments
0.676 0.323 0.000
Z01.6 Radiological examination, not elsewhere classified
0.676 0.324 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.676 0.324 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.676 0.324 0.000
Z40 Prophylactic surgery
0.675 0.325 0.000
M88 Paget's disease of bone [osteitis deformans]
0.674 0.326 0.000
M21.2 Flexion deformity
0.674 0.326 0.000
F38 Other mood [affective] disorders
0.674 0.326 0.000
F34 Persistent mood [affective] disorders
0.674 0.326 0.000
F30 Manic episode
0.674 0.326 0.000
F39 Unspecified mood [affective] disorder
0.674 0.326 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.673 0.327 0.000
G44.2 Tension-type headache
0.671 0.329 0.000
H55-H59 Other disorders of eye and adnexa
0.671 0.329 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.671 0.329 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.670 0.329 0.000
G20-G26 Extrapyramidal and movement disorders
0.670 0.329 0.000
Z09.0 Follow-up examination after surgery for other conditions
0.670 0.330 0.000
S80 Superficial injury of lower leg
0.670 0.330 0.000
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified
0.670 0.330 0.000
M10.4 Other secondary gout
0.668 0.331 0.000
M10.3 Gout due to impairment of renal function
0.668 0.331 0.000
M10.2 Drug-induced gout
0.668 0.331 0.000
M10.1 Lead-induced gout
0.668 0.331 0.000
M10.0 Idiopathic gout
0.668 0.331 0.000
Z03.2 Observation for suspected mental and behavioural disorders
0.668 0.331 0.000
Z03.0 Observation for suspected tuberculosis
0.668 0.331 0.000
F31.9 Bipolar affective disorder, unspecified
0.668 0.332 0.000
M79.7 Fibromyalgia
0.668 0.332 0.000
I09 Other rheumatic heart diseases
0.668 0.332 0.000
I06 Rheumatic aortic valve diseases
0.668 0.332 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.667 0.332 0.000
M45 Ankylosing spondylitis
0.666 0.334 0.000
I72 Other aneurysm
0.666 0.334 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.666 0.334 0.000
M72 Fibroblastic disorders
0.666 0.334 0.000
V10-V19 Pedal cyclist injured in transport accident
0.665 0.334 0.000
I67.9 Cerebrovascular disease, unspecified
0.665 0.335 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.665 0.335 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.664 0.336 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.664 0.336 0.000
E85 Amyloidosis
0.663 0.337 0.000
E84 Cystic fibrosis
0.663 0.337 0.000
E79 Disorders of purine and pyrimidine metabolism
0.663 0.337 0.000
E77 Disorders of glycoprotein metabolism
0.663 0.337 0.000
E76 Disorders of glycosaminoglycan metabolism
0.663 0.337 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.663 0.337 0.000
E74 Other disorders of carbohydrate metabolism
0.663 0.337 0.000
E73 Lactose intolerance
0.663 0.337 0.000
E72 Other disorders of amino-acid metabolism
0.663 0.337 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.663 0.337 0.000
E70 Disorders of aromatic amino-acid metabolism
0.663 0.337 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.663 0.337 0.000
I70 Atherosclerosis
0.663 0.337 0.000
M21.3 Wrist or foot drop (acquired)
0.663 0.337 0.000
M41 Scoliosis
0.662 0.338 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.662 0.338 0.000
H05 Disorders of orbit
0.662 0.338 0.000
Z44.3 Fitting and adjustment of external breast prosthesis
0.661 0.339 0.000
M43.1 Spondylolisthesis
0.660 0.340 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.659 0.341 0.000
E87.2 Acidosis
0.658 0.342 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.658 0.342 0.000
H70 Mastoiditis and related conditions
0.658 0.342 0.000
H68 Eustachian salpingitis and obstruction
0.658 0.342 0.000
H67 Otitis media in diseases classified elsewhere
0.658 0.342 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.658 0.342 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.657 0.343 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.656 0.343 0.000
G41 Status epilepticus
0.656 0.343 0.000
M23.3 Other meniscus derangements
0.656 0.344 0.000
G90 Disorders of autonomic nervous system
0.656 0.344 0.000
M90 Osteopathies in diseases classified elsewhere
0.656 0.344 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.655 0.345 0.000
M21.1 Varus deformity, not elsewhere classified
0.655 0.345 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.655 0.345 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.654 0.346 0.000
M23.4 Loose body in knee
0.654 0.346 0.000
E27.8 Other specified disorders of adrenal gland
0.654 0.346 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.654 0.346 0.000
M76 Enthesopathies of lower limb, excluding foot
0.653 0.347 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.653 0.347 0.000
M71 Other bursopathies
0.653 0.347 0.000
T98 Sequelae of other and unspecified effects of external causes
0.653 0.347 0.000
T95 Sequelae of burns, corrosions and frostbite
0.653 0.347 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.653 0.347 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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