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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs6698528
log Bayes Factor = 13.1015
Chromosome 1   position 193,503,444  (GRCh37) Explore rs6698528 on Ensembl!
Variant rs6698528 is part of Cluster X0093

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
I25.9 Chronic ischaemic heart disease, unspecified
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
0.999 0.001 0.000
Chapter X Diseases of the respiratory system
0.999 0.001 0.000
B95-B98 Bacterial, viral and other infectious agents
0.998 0.002 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.998 0.002 0.000
J30-J39 Other diseases of upper respiratory tract
0.997 0.003 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.996 0.004 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.995 0.005 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.993 0.007 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.991 0.009 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.987 0.013 0.000
Chapter II Neoplasms
0.987 0.013 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.986 0.014 0.000
I30-I52 Other forms of heart disease
0.980 0.020 0.000
O60-O75 Complications of labour and delivery
0.980 0.020 0.000
J34 Other disorders of nose and nasal sinuses
0.976 0.024 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.956 0.044 0.000
S00-S09 Injuries to the head
0.949 0.051 0.000
J40-J47 Chronic lower respiratory diseases
0.948 0.052 0.000
I49 Other cardiac arrhythmias
0.943 0.057 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.934 0.066 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.933 0.067 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.931 0.069 0.000
M20-M25 Other joint disorders
0.930 0.070 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.926 0.074 0.000
S40-S49 Injuries to the shoulder and upper arm
0.921 0.079 0.000
S00 Superficial injury of head
0.919 0.081 0.000
I74 Arterial embolism and thrombosis
0.908 0.092 0.000
J30 Vasomotor and allergic rhinitis
0.908 0.092 0.000
I21 Acute myocardial infarction
0.906 0.094 0.000
I05-I09 Chronic rheumatic heart diseases
0.906 0.094 0.000
I35 Nonrheumatic aortic valve disorders
0.906 0.094 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.898 0.102 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.897 0.103 0.000
B35-B49 Mycoses
0.892 0.108 0.000
M15-M19 Arthrosis
0.885 0.115 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.884 0.116 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.876 0.124 0.000
M65-M68 Disorders of synovium and tendon
0.870 0.130 0.000
C64-C68 Malignant neoplasms of urinary tract
0.869 0.131 0.000
I38 Endocarditis, valve unspecified
0.868 0.132 0.000
I49.0 Ventricular fibrillation and flutter
0.866 0.134 0.000
C51-C58 Malignant neoplasms of female genital organs
0.864 0.135 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.863 0.137 0.000
I49.5 Sick sinus syndrome
0.860 0.140 0.000
J44 Other chronic obstructive pulmonary disease
0.859 0.141 0.000
M45-M49 Spondylopathies
0.859 0.141 0.000
J43 Emphysema
0.857 0.143 0.000
D80-D89 Certain disorders involving the immune mechanism
0.855 0.145 0.000
I78 Diseases of capillaries
0.854 0.146 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.854 0.146 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.852 0.148 0.000
J33 Nasal polyp
0.847 0.153 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.845 0.155 0.000
J34.3 Hypertrophy of nasal turbinates
0.845 0.155 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.842 0.158 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.841 0.159 0.000
M91-M94 Chondropathies
0.837 0.163 0.000
I35.0 Aortic (valve) stenosis
0.836 0.164 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.835 0.165 0.000
I46 Cardiac arrest
0.834 0.166 0.000
M17 Gonarthrosis [arthrosis of knee]
0.833 0.167 0.000
A30-A49 Other bacterial diseases
0.832 0.168 0.000
O73 Retained placenta and membranes, without haemorrhage
0.830 0.170 0.000
S00.8 Superficial injury of other parts of head
0.830 0.170 0.000
C67 Malignant neoplasm of bladder
0.829 0.171 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.828 0.172 0.000
J90-J94 Other diseases of pleura
0.827 0.173 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.825 0.175 0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified
0.824 0.176 0.000
M23 Internal derangement of knee
0.823 0.177 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.823 0.177 0.000
M17.9 Gonarthrosis, unspecified
0.822 0.178 0.000
J20-J22 Other acute lower respiratory infections
0.821 0.179 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.819 0.181 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.818 0.182 0.000
I21.9 Acute myocardial infarction, unspecified
0.814 0.186 0.000
J34.2 Deviated nasal septum
0.814 0.186 0.000
I72 Other aneurysm
0.810 0.190 0.000
S00.3 Superficial injury of nose
0.809 0.191 0.000
I71 Aortic aneurysm and dissection
0.808 0.192 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.806 0.194 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.806 0.194 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.806 0.194 0.000
I49.3 Ventricular premature depolarisation
0.804 0.196 0.000
J36 Peritonsillar abscess
0.803 0.197 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.803 0.197 0.000
S01 Open wound of head
0.802 0.198 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.801 0.199 0.000
D86 Sarcoidosis
0.801 0.199 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.799 0.201 0.000
M47 Spondylosis
0.799 0.201 0.000
I31 Other diseases of pericardium
0.796 0.204 0.000
O63 Long labour
0.793 0.207 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.792 0.208 0.000
J43.9 Emphysema, unspecified
0.792 0.208 0.000
I30 Acute pericarditis
0.792 0.208 0.000
M23.3 Other meniscus derangements
0.792 0.208 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.792 0.208 0.000
J42 Unspecified chronic bronchitis
0.791 0.209 0.000
J35 Chronic diseases of tonsils and adenoids
0.790 0.210 0.000
J34.0 Abscess, furuncle and carbuncle of nose
0.790 0.210 0.000
J37 Chronic laryngitis and laryngotracheitis
0.789 0.211 0.000
J46 Status asthmaticus
0.788 0.212 0.000
I25.5 Ischaemic cardiomyopathy
0.787 0.213 0.000
I08 Multiple valve diseases
0.787 0.213 0.000
S90-S99 Injuries to the ankle and foot
0.785 0.215 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.780 0.220 0.000
S00.9 Superficial injury of head, part unspecified
0.778 0.222 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.778 0.222 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.778 0.222 0.000
C78.7 Secondary malignant neoplasm of liver
0.778 0.222 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.778 0.222 0.000
D00-D09 In situ neoplasms
0.777 0.223 0.000
M21 Other acquired deformities of limbs
0.777 0.223 0.000
I42 Cardiomyopathy
0.776 0.223 0.000
S50-S59 Injuries to the elbow and forearm
0.776 0.224 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.775 0.225 0.000
A80-A89 Viral infections of the central nervous system
0.775 0.225 0.000
I25.3 Aneurysm of heart
0.773 0.227 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.772 0.228 0.000
Chapter VI Diseases of the nervous system
0.771 0.229 0.000
T79-T79 Certain early complications of trauma
0.769 0.231 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.768 0.232 0.000
I70 Atherosclerosis
0.765 0.234 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.764 0.236 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.762 0.237 0.000
Chapter VII Diseases of the eye and adnexa
0.762 0.238 0.000
I22 Subsequent myocardial infarction
0.762 0.238 0.000
B15-B19 Viral hepatitis
0.761 0.239 0.000
J30.4 Allergic rhinitis, unspecified
0.758 0.242 0.000
A41 Other septicaemia
0.758 0.242 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.758 0.242 0.000
D45 Polycythaemia vera
0.757 0.243 0.000
B37 Candidiasis
0.757 0.243 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.757 0.243 0.000
J30.1 Allergic rhinitis due to pollen
0.756 0.244 0.000
O16 Unspecified maternal hypertension
0.755 0.245 0.000
O69.2 Labour and delivery complicated by other cord entanglement
0.754 0.246 0.000
Chapter XX External causes of morbidity and mortality
0.754 0.246 0.000
M40-M43 Deforming dorsopathies
0.753 0.247 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.753 0.247 0.000
Chapter XXII Codes for special purposes
0.750 0.250 0.000
C56 Malignant neoplasm of ovary
0.749 0.251 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.748 0.252 0.000
I74.5 Embolism and thrombosis of iliac artery
0.748 0.252 0.000
S05 Injury of eye and orbit
0.747 0.253 0.000
I77 Other disorders of arteries and arterioles
0.746 0.254 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.746 0.254 0.000
T92 Sequelae of injuries of upper limb
0.745 0.255 0.000
D86.9 Sarcoidosis, unspecified
0.744 0.256 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.743 0.257 0.000
O85-O92 Complications predominantly related to the puerperium
0.742 0.258 0.000
M25 Other joint disorders, not elsewhere classified
0.742 0.258 0.000
M67 Other disorders of synovium and tendon
0.741 0.259 0.000
C79 Secondary malignant neoplasm of other sites
0.740 0.260 0.000
S10-S19 Injuries to the neck
0.739 0.261 0.000
C77.1 Intrathoracic lymph nodes
0.739 0.261 0.000
S01.5 Open wound of lip and oral cavity
0.737 0.263 0.000
T66-T78 Other and unspecified effects of external causes
0.735 0.265 0.000
M50-M54 Other dorsopathies
0.735 0.265 0.000
I20 Angina pectoris
0.735 0.265 0.000
Chapter VIII Diseases of the ear and mastoid process
0.734 0.266 0.000
I05 Rheumatic mitral valve diseases
0.733 0.267 0.000
S70-S79 Injuries to the hip and thigh
0.732 0.268 0.000
I46.0 Cardiac arrest with successful resuscitation
0.732 0.268 0.000
O48 Prolonged pregnancy
0.731 0.269 0.000
S40 Superficial injury of shoulder and upper arm
0.730 0.270 0.000
J95-J99 Other diseases of the respiratory system
0.729 0.270 0.000
J32 Chronic sinusitis
0.728 0.272 0.000
J33.8 Other polyp of sinus
0.727 0.273 0.000
M86-M90 Other osteopathies
0.725 0.275 0.000
S46.0 Injury of tendon of the rotator cuff of shoulder
0.724 0.276 0.000
B44 Aspergillosis
0.723 0.277 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.723 0.277 0.000
O73.0 Retained placenta, without haemorrhage
0.723 0.277 0.000
I78.1 Naevus, nonneoplastic
0.723 0.277 0.000
D41.4 Bladder
0.722 0.278 0.000
J30.3 Other allergic rhinitis
0.722 0.278 0.000
I73 Other peripheral vascular diseases
0.721 0.279 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.721 0.279 0.000
M22 Disorders of patella
0.719 0.281 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.718 0.282 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.718 0.282 0.000
C67.8 Overlapping lesion of bladder
0.718 0.282 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.718 0.282 0.000
M80-M85 Disorders of bone density and structure
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
C77.3 Axillary and upper limb lymph nodes
0.717 0.283 0.000
S06 Intracranial injury
0.717 0.283 0.000
B99-B99 Other infectious diseases
0.716 0.283 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.716 0.283 0.000
B65-B83 Helminthiases
0.716 0.283 0.000
B50-B64 Protozoal diseases
0.716 0.283 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.716 0.283 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.716 0.283 0.000
A75-A79 Rickettsioses
0.716 0.283 0.000
A70-A74 Other diseases caused by chlamydiae
0.716 0.283 0.000
A65-A69 Other spirochaetal diseases
0.716 0.283 0.000
A20-A28 Certain zoonotic bacterial diseases
0.716 0.283 0.000
A15-A19 Tuberculosis
0.716 0.283 0.000
M47.8 Other spondylosis
0.716 0.284 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.716 0.284 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.715 0.285 0.000
I33 Acute and subacute endocarditis
0.715 0.285 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.715 0.285 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.715 0.285 0.000
I31.3 Pericardial effusion (noninflammatory)
0.715 0.285 0.000
O47 False labour
0.715 0.285 0.000
T93 Sequelae of injuries of lower limb
0.715 0.285 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.714 0.286 0.000
T33-T35 Frostbite
0.714 0.286 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.714 0.286 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.714 0.286 0.000
T00-T07 Injuries involving multiple body regions
0.714 0.286 0.000
M60-M63 Disorders of muscles
0.712 0.288 0.000
M00-M03 Infectious arthropathies
0.712 0.288 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.710 0.290 0.000
S42 Fracture of shoulder and upper arm
0.709 0.291 0.000
C44 Other malignant neoplasms of skin
0.708 0.292 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.707 0.293 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.707 0.293 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.707 0.293 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.707 0.293 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.706 0.293 0.000
C67.4 Posterior wall of bladder
0.705 0.295 0.000
S20-S29 Injuries to the thorax
0.703 0.297 0.000
M65 Synovitis and tenosynovitis
0.703 0.297 0.000
I52 Other heart disorders in diseases classified elsewhere
0.703 0.297 0.000
I48 Atrial fibrillation and flutter
0.703 0.297 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.703 0.297 0.000
I41 Myocarditis in diseases classified elsewhere
0.703 0.297 0.000
I40 Acute myocarditis
0.703 0.297 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.703 0.297 0.000
I37 Pulmonary valve disorders
0.703 0.297 0.000
I36 Nonrheumatic tricuspid valve disorders
0.703 0.297 0.000
I32 Pericarditis in diseases classified elsewhere
0.703 0.297 0.000
O74 Complications of anaesthesia during labour and delivery
0.702 0.297 0.000
O71 Other obstetric trauma
0.702 0.297 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.702 0.297 0.000
O61 Failed induction of labour
0.702 0.297 0.000
O60 Preterm delivery
0.702 0.297 0.000
M05-M14 Inflammatory polyarthropathies
0.702 0.298 0.000
O62 Abnormalities of forces of labour
0.702 0.298 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.702 0.298 0.000
J34.1 Cyst and mucocele of nose and nasal sinus
0.700 0.300 0.000
G40-G47 Episodic and paroxysmal disorders
0.698 0.302 0.000
O63.9 Long labour, unspecified
0.697 0.303 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.696 0.303 0.000
C78.0 Secondary malignant neoplasm of lung
0.695 0.305 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.695 0.305 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.694 0.306 0.000
M24 Other specific joint derangements
0.691 0.309 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.691 0.309 0.000
I07 Rheumatic tricuspid valve diseases
0.690 0.310 0.000
G90-G99 Other disorders of the nervous system
0.688 0.312 0.000
D72 Other disorders of white blood cells
0.688 0.312 0.000
I45 Other conduction disorders
0.687 0.313 0.000
J91 Pleural effusion in conditions classified elsewhere
0.686 0.314 0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress
0.686 0.314 0.000
M47.9 Spondylosis, unspecified
0.685 0.315 0.000
O45 Premature separation of placenta [abruptio placentae]
0.684 0.316 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.684 0.316 0.000
C44.1 Skin of eyelid, including canthus
0.684 0.316 0.000
D73 Diseases of spleen
0.682 0.318 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.682 0.318 0.000
D75 Other diseases of blood and blood-forming organs
0.682 0.318 0.000
I49.1 Atrial premature depolarisation
0.681 0.318 0.000
J22 Unspecified acute lower respiratory infection
0.681 0.319 0.000
I78.0 Hereditary haemorrhagic telangiectasia
0.681 0.319 0.000
S08 Traumatic amputation of part of head
0.680 0.320 0.000
S07 Crushing injury of head
0.680 0.320 0.000
S04 Injury of cranial nerves
0.680 0.320 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.680 0.320 0.000
J41 Simple and mucopurulent chronic bronchitis
0.680 0.320 0.000
M47.86 Other spondylosis (Lumbar region)
0.679 0.321 0.000
B35 Dermatophytosis
0.678 0.322 0.000
H80-H83 Diseases of inner ear
0.677 0.323 0.000
I49.2 Junctional premature depolarisation
0.676 0.323 0.000
T87 Complications peculiar to reattachment and amputation
0.675 0.325 0.000
B37.3 Candidiasis of vulva and vagina
0.674 0.326 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.673 0.327 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.673 0.327 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.671 0.329 0.000
J90 Pleural effusion, not elsewhere classified
0.671 0.329 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.670 0.330 0.000
I49.8 Other specified cardiac arrhythmias
0.669 0.331 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.669 0.331 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.669 0.331 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.669 0.331 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.669 0.331 0.000
M94 Other disorders of cartilage
0.669 0.331 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.669 0.331 0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters
0.669 0.331 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.669 0.331 0.000
I08.0 Disorders of both mitral and aortic valves
0.669 0.331 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.668 0.331 0.000
T90 Sequelae of injuries of head
0.668 0.331 0.000
G40 Epilepsy
0.669 0.331 0.000
C73 Malignant neoplasm of thyroid gland
0.668 0.332 0.000
J33.9 Nasal polyp, unspecified
0.668 0.332 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.667 0.333 0.000
M34 Systemic sclerosis
0.667 0.333 0.000
M33 Dermatopolymyositis
0.667 0.333 0.000
M32 Systemic lupus erythematosus
0.667 0.333 0.000
M30 Polyarteritis nodosa and related conditions
0.667 0.333 0.000
H53-H54 Visual disturbances and blindness
0.667 0.333 0.000
M21.1 Varus deformity, not elsewhere classified
0.666 0.334 0.000
S01.0 Open wound of scalp
0.665 0.335 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.664 0.336 0.000
D55-D59 Haemolytic anaemias
0.664 0.336 0.000
C67.6 Ureteric orifice
0.663 0.337 0.000
C15-C26 Malignant neoplasms of digestive organs
0.663 0.337 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.661 0.339 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.661 0.339 0.000
M92 Other juvenile osteochondrosis
0.660 0.340 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.660 0.340 0.000
S48 Traumatic amputation of shoulder and upper arm
0.660 0.340 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.660 0.340 0.000
S44 Injury of nerves at shoulder and upper arm level
0.660 0.340 0.000
S41 Open wound of shoulder and upper arm
0.660 0.340 0.000
S47 Crushing injury of shoulder and upper arm
0.660 0.340 0.000
D68 Other coagulation defects
0.660 0.340 0.000
I35.9 Aortic valve disorder, unspecified
0.659 0.341 0.000
S00.7 Multiple superficial injuries of head
0.659 0.341 0.000
S00.5 Superficial injury of lip and oral cavity
0.659 0.341 0.000
S00.4 Superficial injury of ear
0.659 0.341 0.000
D41.0 Kidney
0.659 0.341 0.000
I30.9 Acute pericarditis, unspecified
0.657 0.343 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.656 0.344 0.000
C53 Malignant neoplasm of cervix uteri
0.655 0.345 0.000
C67.2 Lateral wall of bladder
0.655 0.345 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.655 0.345 0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress
0.654 0.346 0.000
O66 Other obstructed labour
0.652 0.347 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.652 0.347 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.651 0.349 0.000
I74.8 Embolism and thrombosis of other arteries
0.651 0.349 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.651 0.349 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.651 0.349 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.651 0.349 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.651 0.349 0.000
J30.2 Other seasonal allergic rhinitis
0.651 0.349 0.000
J30.0 Vasomotor rhinitis
0.651 0.349 0.000
D05 Carcinoma in situ of breast
0.650 0.350 0.000
O80-O84 Delivery
0.650 0.350 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.650 0.350 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.650 0.350 0.000
I09 Other rheumatic heart diseases
0.649 0.350 0.000
I06 Rheumatic aortic valve diseases
0.649 0.350 0.000
I35.8 Other aortic valve disorders
0.649 0.351 0.000
I20.0 Unstable angina
0.648 0.352 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.647 0.352 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.647 0.353 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.647 0.353 0.000
D86.0 Sarcoidosis of lung
0.647 0.353 0.000
M35 Other systemic involvement of connective tissue
0.646 0.354 0.000
M17.3 Other posttraumatic gonarthrosis
0.646 0.354 0.000
T92.1 Sequelae of fracture of arm
0.646 0.354 0.000
M25.7 Osteophyte
0.646 0.354 0.000
M23.9 Internal derangement of knee, unspecified
0.645 0.355 0.000
C77.9 Lymph node, unspecified
0.644 0.356 0.000
M18 Arthrosis of first carpometacarpal joint
0.643 0.357 0.000
O72 Postpartum haemorrhage
0.643 0.357 0.000
S32 Fracture of lumbar spine and pelvis
0.642 0.358 0.000
J37.0 Chronic laryngitis
0.641 0.359 0.000
O63.0 Prolonged first stage (of labour)
0.641 0.359 0.000
B48 Other mycoses, not elsewhere classified
0.640 0.360 0.000
B47 Mycetoma
0.640 0.360 0.000
B46 Zygomycosis
0.640 0.360 0.000
B45 Cryptococcosis
0.640 0.360 0.000
B43 Chromomycosis and phaeomycotic abscess
0.640 0.360 0.000
B42 Sporotrichosis
0.640 0.360 0.000
B41 Paracoccidioidomycosis
0.640 0.360 0.000
B40 Blastomycosis
0.640 0.360 0.000
B39 Histoplasmosis
0.640 0.360 0.000
B38 Coccidioidomycosis
0.640 0.360 0.000
B36 Other superficial mycoses
0.640 0.360 0.000
B49 Unspecified mycosis
0.640 0.360 0.000
S00.1 Contusion of eyelid and periocular area
0.639 0.361 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.638 0.362 0.000
A41.9 Septicaemia, unspecified
0.638 0.362 0.000
M20 Acquired deformities of fingers and toes
0.638 0.362 0.000
J09-J18 Influenza and pneumonia
0.637 0.363 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.636 0.364 0.000
O69.1 Labour and delivery complicated by cord around neck, with compression
0.635 0.365 0.000
I72.8 Aneurysm of other specified arteries
0.635 0.365 0.000
M15 Polyarthrosis
0.634 0.366 0.000
I72.0 Aneurysm of carotid artery
0.634 0.366 0.000
T98 Sequelae of other and unspecified effects of external causes
0.633 0.366 0.000
T95 Sequelae of burns, corrosions and frostbite
0.633 0.366 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.633 0.366 0.000
T91 Sequelae of injuries of neck and trunk
0.633 0.366 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.633 0.366 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.633 0.366 0.000
D46 Myelodysplastic syndromes
0.633 0.366 0.000
O43 Placental disorders
0.633 0.367 0.000
S00.0 Superficial injury of scalp
0.633 0.367 0.000
M22.2 Patellofemoral disorders
0.632 0.368 0.000
B25-B34 Other viral diseases
0.631 0.369 0.000
V10-V19 Pedal cyclist injured in transport accident
0.631 0.369 0.000
J60-J70 Lung diseases due to external agents
0.631 0.369 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.631 0.369 0.000
C44.0 Skin of lip
0.630 0.370 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.630 0.370 0.000
J94 Other pleural conditions
0.629 0.371 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.629 0.371 0.000
H30-H36 Disorders of choroid and retina
0.628 0.371 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.628 0.372 0.000
I42.0 Dilated cardiomyopathy
0.628 0.372 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.627 0.373 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.627 0.373 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.627 0.373 0.000
A41.8 Other specified septicaemia
0.626 0.373 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.626 0.374 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.625 0.375 0.000
A00-A09 Intestinal infectious diseases
0.625 0.375 0.000
H54 Blindness and low vision
0.624 0.376 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.624 0.376 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.624 0.376 0.000
M66 Spontaneous rupture of synovium and tendon
0.624 0.376 0.000
J35.0 Chronic tonsillitis
0.624 0.376 0.000
S50 Superficial injury of forearm
0.624 0.376 0.000
M93 Other osteochondropathies
0.624 0.376 0.000
S91 Open wound of ankle and foot
0.623 0.376 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.623 0.377 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.623 0.377 0.000
C66 Malignant neoplasm of ureter
0.623 0.377 0.000
C65 Malignant neoplasm of renal pelvis
0.623 0.377 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.622 0.378 0.000
M31 Other necrotising vasculopathies
0.621 0.378 0.000
T23 Burn and corrosion of wrist and hand
0.621 0.378 0.000
J31.0 Chronic rhinitis
0.621 0.379 0.000
T86 Failure and rejection of transplanted organs and tissues
0.620 0.380 0.000
H83 Other diseases of inner ear
0.620 0.380 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.620 0.380 0.000
C51 Malignant neoplasm of vulva
0.620 0.380 0.000
C58 Malignant neoplasm of placenta
0.620 0.380 0.000
C52 Malignant neoplasm of vagina
0.620 0.380 0.000
M23.5 Chronic instability of knee
0.620 0.380 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.620 0.380 0.000
Q50-Q56 Congenital malformations of genital organs
0.619 0.380 0.000
J39 Other diseases of upper respiratory tract
0.619 0.380 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.619 0.381 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.619 0.381 0.000
O15 Eclampsia
0.618 0.381 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.618 0.381 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.618 0.381 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.618 0.381 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.617 0.383 0.000
C80 Malignant neoplasm without specification of site
0.617 0.383 0.000
S40.0 Contusion of shoulder and upper arm
0.617 0.383 0.000
G93 Other disorders of brain
0.616 0.384 0.000
O67.9 Intrapartum haemorrhage, unspecified
0.616 0.384 0.000
M50 Cervical disk disorders
0.616 0.384 0.000
I21.4 Acute subendocardial myocardial infarction
0.616 0.384 0.000
M49 Spondylopathies in diseases classified elsewhere
0.616 0.384 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.616 0.384 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.615 0.384 0.000
M16 Coxarthrosis [arthrosis of hip]
0.615 0.385 0.000
C67.9 Bladder, unspecified
0.615 0.385 0.000
J43.8 Other emphysema
0.615 0.385 0.000
J43.2 Centrilobular emphysema
0.615 0.385 0.000
J43.1 Panlobular emphysema
0.615 0.385 0.000
J43.0 MacLeod's syndrome
0.615 0.385 0.000
A87 Viral meningitis
0.614 0.386 0.000
Q80-Q89 Other congenital malformations
0.614 0.386 0.000
G40.9 Epilepsy, unspecified
0.613 0.387 0.000
D84 Other immunodeficiencies
0.613 0.387 0.000
D83 Common variable immunodeficiency
0.613 0.387 0.000
D82 Immunodeficiency associated with other major defects
0.613 0.387 0.000
D81 Combined immunodeficiencies
0.613 0.387 0.000
D80 Immunodeficiency with predominantly antibody defects
0.613 0.387 0.000
M25.4 Effusion of joint
0.613 0.387 0.000
I78.9 Disease of capillaries, unspecified
0.613 0.387 0.000
I78.8 Other diseases of capillaries
0.613 0.387 0.000
J93 Pneumothorax
0.612 0.388 0.000
O69.9 Labour and delivery complicated by cord complication, unspecified
0.612 0.388 0.000
O69.8 Labour and delivery complicated by other cord complications
0.612 0.388 0.000
O69.5 Labour and delivery complicated by vascular lesion of cord
0.612 0.388 0.000
O69.4 Labour and delivery complicated by vasa praevia
0.612 0.388 0.000
O69.3 Labour and delivery complicated by short cord
0.612 0.388 0.000
O69.0 Labour and delivery complicated by prolapse of cord
0.612 0.388 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.612 0.388 0.000
D39.1 Ovary
0.611 0.389 0.000
O44 Placenta praevia
0.611 0.389 0.000
O41 Other disorders of amniotic fluid and membranes
0.611 0.389 0.000
O33 Maternal care for known or suspected disproportion
0.611 0.389 0.000
O31 Complications specific to multiple gestation
0.611 0.389 0.000
O40 Polyhydramnios
0.611 0.389 0.000
I05.9 Mitral valve disease, unspecified
0.610 0.390 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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