TreeWAS – Variant ID: rs78643014

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter IX Diseases of the circulatory system	1.000	0.000
# Top node	1.000	0.000
I60-I69 Cerebrovascular diseases	1.000	0.000
I30-I52 Other forms of heart disease	0.999	0.001
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.999	0.001
I69 Sequelae of cerebrovascular disease	0.997	0.003
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.996	0.004
Chapter II Neoplasms	0.992	0.008
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.991	0.009
Chapter VI Diseases of the nervous system	0.991	0.009
D10-D36 Benign neoplasms	0.988	0.012
I42 Cardiomyopathy	0.987	0.013
G80-G83 Cerebral palsy and other paralytic syndromes	0.979	0.021
Chapter XV Pregnancy, childbirth and the puerperium	0.970	0.030
I20-I25 Ischaemic heart diseases	0.965	0.035
G81 Hemiplegia	0.964	0.036
C43-C44 Melanoma and other malignant neoplasms of skin	0.964	0.036
I05-I09 Chronic rheumatic heart diseases	0.956	0.044
C44 Other malignant neoplasms of skin	0.956	0.044
G81.9 Hemiplegia, unspecified	0.953	0.047
I35 Nonrheumatic aortic valve disorders	0.949	0.051
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.949	0.051
M20-M25 Other joint disorders	0.949	0.051
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.941	0.059
M70-M79 Other soft tissue disorders	0.937	0.063
Chapter I Certain infectious and parasitic diseases	0.930	0.070
Chapter VII Diseases of the eye and adnexa	0.929	0.071
I20 Angina pectoris	0.924	0.076
I42.0 Dilated cardiomyopathy	0.923	0.077
O20-O29 Other maternal disorders predominantly related to pregnancy	0.920	0.080
I08 Multiple valve diseases	0.912	0.088
I42.9 Cardiomyopathy, unspecified	0.908	0.092
I69.3 Sequelae of cerebral infarction	0.907	0.093
I20.0 Unstable angina	0.901	0.099
I60 Subarachnoid haemorrhage	0.900	0.100
D27 Benign neoplasm of ovary	0.899	0.101
C44.3 Skin of other and unspecified parts of face	0.897	0.103
C44.6 Skin of upper limb, including shoulder	0.893	0.107
T66-T78 Other and unspecified effects of external causes	0.892	0.108
M23 Internal derangement of knee	0.890	0.110
D13.1 Stomach	0.888	0.112
I45 Other conduction disorders	0.882	0.118
C51-C58 Malignant neoplasms of female genital organs	0.882	0.118
N17-N19 Renal failure	0.881	0.119
N18 Chronic renal failure	0.881	0.119
N18.9 Chronic renal failure, unspecified	0.878	0.122
D34 Benign neoplasm of thyroid gland	0.875	0.125
S90-S99 Injuries to the ankle and foot	0.871	0.129
M24 Other specific joint derangements	0.871	0.129
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.870	0.129
M75 Shoulder lesions	0.869	0.131
I51 Complications and ill-defined descriptions of heart disease	0.866	0.134
Chapter V Mental and behavioural disorders	0.863	0.137
Chapter XIV Diseases of the genitourinary system	0.861	0.139
O94-O99 Other obstetric conditions, not elsewhere classified	0.857	0.143
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.857	0.143
S32 Fracture of lumbar spine and pelvis	0.854	0.146
D32 Benign neoplasm of meninges	0.854	0.146
I35.2 Aortic (valve) stenosis with insufficiency	0.852	0.148
O20 Haemorrhage in early pregnancy	0.850	0.150
I67 Other cerebrovascular diseases	0.850	0.150
M15-M19 Arthrosis	0.850	0.150
C44.4 Skin of scalp and neck	0.848	0.152
M05-M14 Inflammatory polyarthropathies	0.846	0.154
I63 Cerebral infarction	0.845	0.155
B35-B49 Mycoses	0.845	0.155
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.844	0.156
D29 Benign neoplasm of male genital organs	0.843	0.157
G00-G09 Inflammatory diseases of the central nervous system	0.839	0.161
G70-G73 Diseases of myoneural junction and muscle	0.837	0.163
M21 Other acquired deformities of limbs	0.835	0.165
D18 Haemangioma and lymphangioma, any site	0.834	0.166
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.834	0.166
I22 Subsequent myocardial infarction	0.831	0.169
I35.9 Aortic valve disorder, unspecified	0.829	0.171
N17 Acute renal failure	0.829	0.171
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.828	0.172
N18.3 Chronic kidney disease, stage 3	0.827	0.173
M79 Other soft tissue disorders, not elsewhere classified	0.826	0.174
D16 Benign neoplasm of bone and articular cartilage	0.825	0.175
I35.0 Aortic (valve) stenosis	0.824	0.176
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.823	0.177
C44.5 Skin of trunk	0.820	0.180
I46 Cardiac arrest	0.819	0.181
I31 Other diseases of pericardium	0.818	0.182
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.812	0.188
I08.0 Disorders of both mitral and aortic valves	0.810	0.190
T81 Complications of procedures, not elsewhere classified	0.810	0.190
M45-M49 Spondylopathies	0.810	0.190
I25 Chronic ischaemic heart disease	0.809	0.191
G40-G47 Episodic and paroxysmal disorders	0.808	0.192
G82 Paraplegia and tetraplegia	0.805	0.195
S80-S89 Injuries to the knee and lower leg	0.804	0.196
H25-H28 Disorders of lens	0.802	0.198
H46-H48 Disorders of optic nerve and visual pathways	0.801	0.199
M19 Other arthrosis	0.800	0.200
M60-M63 Disorders of muscles	0.800	0.200
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.800	0.200
F00-F09 Organic, including symptomatic, mental disorders	0.796	0.204
A30-A49 Other bacterial diseases	0.796	0.204
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.794	0.206
F30-F39 Mood [affective] disorders	0.793	0.207
C44.7 Skin of lower limb, including hip	0.793	0.207
I08.1 Disorders of both mitral and tricuspid valves	0.793	0.207
N17.9 Acute renal failure, unspecified	0.792	0.208
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.790	0.210
M23.2 Derangement of meniscus due to old tear or injury	0.788	0.212
D11 Benign neoplasm of major salivary glands	0.787	0.213
C56 Malignant neoplasm of ovary	0.787	0.213
N19 Unspecified renal failure	0.787	0.213
B44 Aspergillosis	0.786	0.214
M86-M90 Other osteopathies	0.786	0.214
T68 Hypothermia	0.784	0.216
T20-T25 Burns and corrosions of external body surface, specified by site	0.782	0.218
I49 Other cardiac arrhythmias	0.782	0.218
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.782	0.218
I62 Other nontraumatic intracranial haemorrhage	0.780	0.220
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.777	0.223
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.774	0.226
D13.0 Oesophagus	0.773	0.227
D21 Other benign neoplasms of connective and other soft tissue	0.772	0.228
T36-T50 Poisoning by drugs, medicaments and biological substances	0.772	0.228
M75.1 Rotator cuff syndrome	0.772	0.228
S40-S49 Injuries to the shoulder and upper arm	0.771	0.229
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.770	0.230
I42.8 Other cardiomyopathies	0.770	0.230
M24.1 Other articular cartilage disorders	0.769	0.231
S10-S19 Injuries to the neck	0.769	0.231
M22 Disorders of patella	0.768	0.232
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.768	0.232
M19.0 Primary arthrosis of other joints	0.768	0.232
Chapter XXII Codes for special purposes	0.766	0.233
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.766	0.234
G90-G99 Other disorders of the nervous system	0.765	0.235
I42.2 Other hypertrophic cardiomyopathy	0.765	0.235
I50 Heart failure	0.764	0.236
M23.3 Other meniscus derangements	0.762	0.238
M75.3 Calcific tendinitis of shoulder	0.761	0.239
I34 Nonrheumatic mitral valve disorders	0.761	0.239
I51.9 Heart disease, unspecified	0.760	0.240
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.759	0.241
D13.5 Extrahepatic bile ducts	0.759	0.241
S91 Open wound of ankle and foot	0.759	0.241
O20.0 Threatened abortion	0.758	0.242
I42.1 Obstructive hypertrophic cardiomyopathy	0.758	0.242
D33 Benign neoplasm of brain and other parts of central nervous system	0.753	0.246
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.753	0.247
G20-G26 Extrapyramidal and movement disorders	0.753	0.247
G80 Infantile cerebral palsy	0.750	0.250
G43 Migraine	0.749	0.251
S70-S79 Injuries to the hip and thigh	0.748	0.252
I45.1 Other and unspecified right bundle-branch block	0.748	0.252
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.747	0.253
D17 Benign lipomatous neoplasm	0.745	0.255
D14 Benign neoplasm of middle ear and respiratory system	0.744	0.256
T81.3 Disruption of operation wound, not elsewhere classified	0.744	0.256
M75.5 Bursitis of shoulder	0.743	0.257
H43-H45 Disorders of vitreous body and globe	0.743	0.257
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.742	0.258
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.741	0.259
O80-O84 Delivery	0.741	0.259
C53 Malignant neoplasm of cervix uteri	0.740	0.260
I07 Rheumatic tricuspid valve diseases	0.740	0.260
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.739	0.261
N18.8 Other chronic renal failure	0.738	0.262
M65-M68 Disorders of synovium and tendon	0.738	0.262
O00-O08 Pregnancy with abortive outcome	0.737	0.263
F33 Recurrent depressive disorder	0.737	0.263
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.734	0.266
Chapter VIII Diseases of the ear and mastoid process	0.733	0.267
O26 Maternal care for other conditions predominantly related to pregnancy	0.732	0.268
I20.8 Other forms of angina pectoris	0.731	0.268
M21.0 Valgus deformity, not elsewhere classified	0.731	0.269
I67.9 Cerebrovascular disease, unspecified	0.731	0.269
D32.0 Cerebral meninges	0.729	0.271
I69.1 Sequelae of intracerebral haemorrhage	0.728	0.272
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.728	0.272
M23.9 Internal derangement of knee, unspecified	0.728	0.272
D28 Benign neoplasm of other and unspecified female genital organs	0.727	0.273
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.727	0.273
I25.2 Old myocardial infarction	0.727	0.273
B95-B98 Bacterial, viral and other infectious agents	0.727	0.273
D30 Benign neoplasm of urinary organs	0.727	0.273
I64 Stroke, not specified as haemorrhage or infarction	0.726	0.274
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.724	0.276
T14 Injury of unspecified body region	0.724	0.276
D18.0 Haemangioma, any site	0.723	0.277
I60.9 Subarachnoid haemorrhage, unspecified	0.722	0.278
A49 Bacterial infection of unspecified site	0.721	0.279
S32.4 Fracture of acetabulum	0.721	0.279
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.720	0.280
T85 Complications of other internal prosthetic devices, implants and grafts	0.719	0.281
O20.9 Haemorrhage in early pregnancy, unspecified	0.718	0.282
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.717	0.283
I00-I02 Acute rheumatic fever	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
I05 Rheumatic mitral valve diseases	0.717	0.283
I68 Cerebrovascular disorders in diseases classified elsewhere	0.717	0.283
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.717	0.283
I52 Other heart disorders in diseases classified elsewhere	0.716	0.283
I48 Atrial fibrillation and flutter	0.716	0.283
I43 Cardiomyopathy in diseases classified elsewhere	0.716	0.283
I41 Myocarditis in diseases classified elsewhere	0.716	0.283
I40 Acute myocarditis	0.716	0.283
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.716	0.283
I37 Pulmonary valve disorders	0.716	0.283
I36 Nonrheumatic tricuspid valve disorders	0.716	0.283
I32 Pericarditis in diseases classified elsewhere	0.716	0.283
I30 Acute pericarditis	0.716	0.283
T33-T35 Frostbite	0.716	0.284
T26-T28 Burns and corrosions confined to eye and internal organs	0.716	0.284
T00-T07 Injuries involving multiple body regions	0.716	0.284
T13 Other injuries of lower limb, level unspecified	0.716	0.284
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.715	0.285
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.715	0.285
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.715	0.285
M91-M94 Chondropathies	0.714	0.286
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.714	0.286
T78 Adverse effects, not elsewhere classified	0.714	0.286
O34 Maternal care for known or suspected abnormality of pelvic organs	0.713	0.287
O21 Excessive vomiting in pregnancy	0.712	0.288
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.711	0.289
C40-C41 Malignant neoplasms of bone and articular cartilage	0.711	0.289
C73 Malignant neoplasm of thyroid gland	0.711	0.289
M00-M03 Infectious arthropathies	0.710	0.290
I69.0 Sequelae of subarachnoid haemorrhage	0.709	0.291
D31 Benign neoplasm of eye and adnexa	0.709	0.291
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.709	0.291
D19 Benign neoplasm of mesothelial tissue	0.709	0.291
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.709	0.291
D29.4 Scrotum	0.707	0.292
I42.7 Cardiomyopathy due to drugs and other external agents	0.707	0.292
I42.6 Alcoholic cardiomyopathy	0.707	0.292
I42.5 Other restrictive cardiomyopathy	0.707	0.292
I42.4 Endocardial fibroelastosis	0.707	0.292
I42.3 Endomyocardial (eosinophilic) disease	0.707	0.292
M18 Arthrosis of first carpometacarpal joint	0.706	0.294
O32 Maternal care for known or suspected malpresentation of foetus	0.706	0.294
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.706	0.294
B44.1 Other pulmonary aspergillosis	0.706	0.294
S30 Superficial injury of abdomen, lower back and pelvis	0.705	0.295
I46.9 Cardiac arrest, unspecified	0.704	0.296
I25.9 Chronic ischaemic heart disease, unspecified	0.703	0.297
I45.9 Conduction disorder, unspecified	0.703	0.297
B25-B34 Other viral diseases	0.703	0.297
I60.8 Other subarachnoid haemorrhage	0.701	0.299
I50.0 Congestive heart failure	0.700	0.300
I31.9 Disease of pericardium, unspecified	0.700	0.300
I22.0 Subsequent myocardial infarction of anterior wall	0.700	0.300
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.700	0.300
O24 Diabetes mellitus in pregnancy	0.699	0.301
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.698	0.302
S32.3 Fracture of ilium	0.698	0.302
G70 Myasthenia gravis and other myoneural disorders	0.697	0.303
T79-T79 Certain early complications of trauma	0.696	0.304
M34 Systemic sclerosis	0.696	0.304
G43.9 Migraine, unspecified	0.696	0.304
O85-O92 Complications predominantly related to the puerperium	0.695	0.305
H02 Other disorders of eyelid	0.694	0.306
M22.4 Chondromalacia patellae	0.694	0.306
S32.5 Fracture of pubis	0.694	0.306
D10 Benign neoplasm of mouth and pharynx	0.693	0.307
I23 Certain current complications following acute myocardial infarction	0.692	0.308
H47 Other disorders of optic [2nd] nerve and visual pathways	0.692	0.308
S20-S29 Injuries to the thorax	0.692	0.308
G81.1 Spastic hemiplegia	0.691	0.309
G81.0 Flaccid hemiplegia	0.691	0.309
I51.7 Cardiomegaly	0.690	0.310
D35 Benign neoplasm of other and unspecified endocrine glands	0.688	0.312
S89 Other and unspecified injuries of lower leg	0.688	0.312
I49.8 Other specified cardiac arrhythmias	0.686	0.314
G83 Other paralytic syndromes	0.686	0.314
I09 Other rheumatic heart diseases	0.686	0.314
I06 Rheumatic aortic valve diseases	0.686	0.314
C44.9 Malignant neoplasm of skin, unspecified	0.686	0.314
C44.8 Overlapping lesion of skin	0.686	0.314
D26 Other benign neoplasms of uterus	0.685	0.314
M24.2 Disorder of ligament	0.685	0.315
M13 Other arthritis	0.685	0.315
M19.1 Posttraumatic arthrosis of other joints	0.683	0.317
M70 Soft tissue disorders related to use, overuse and pressure	0.683	0.317
M79.0 Rheumatism, unspecified	0.683	0.317
G30-G32 Other degenerative diseases of the nervous system	0.682	0.318
M80-M85 Disorders of bone density and structure	0.681	0.319
M75.9 Shoulder lesion, unspecified	0.681	0.319
Q60-Q64 Congenital malformations of the urinary system	0.680	0.320
Q00-Q07 Congenital malformations of the nervous system	0.680	0.320
D13.9 Ill-defined sites within the digestive system	0.680	0.320
D13.7 Endocrine pancreas	0.680	0.320
D13.6 Pancreas	0.680	0.320
D13.4 Liver	0.680	0.320
D13.3 Other and unspecified parts of small intestine	0.680	0.320
D13.2 Duodenum	0.680	0.320
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.680	0.320
M33 Dermatopolymyositis	0.680	0.320
M32 Systemic lupus erythematosus	0.680	0.320
M30 Polyarteritis nodosa and related conditions	0.680	0.320
D16.3 Short bones of lower limb	0.680	0.320
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.680	0.320
I45.5 Other specified heart block	0.679	0.321
G03 Meningitis due to other and unspecified causes	0.678	0.322
G04 Encephalitis, myelitis and encephalomyelitis	0.678	0.322
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.678	0.322
H55-H59 Other disorders of eye and adnexa	0.677	0.323
S80 Superficial injury of lower leg	0.677	0.323
M79.8 Other specified soft tissue disorders	0.676	0.324
M23.5 Chronic instability of knee	0.676	0.324
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.675	0.325
S37 Injury of urinary and pelvic organs	0.675	0.325
S36 Injury of intra-abdominal organs	0.675	0.325
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.675	0.325
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.675	0.325
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.675	0.325
S31 Open wound of abdomen, lower back and pelvis	0.675	0.325
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites	0.673	0.327
M76 Enthesopathies of lower limb, excluding foot	0.672	0.328
M73 Soft tissue disorders in diseases classified elsewhere	0.672	0.328
S92 Fracture of foot, except ankle	0.671	0.329
M06 Other rheumatoid arthritis	0.671	0.329
I24 Other acute ischaemic heart diseases	0.670	0.330
B44.9 Aspergillosis, unspecified	0.670	0.330
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.669	0.331
I38 Endocarditis, valve unspecified	0.668	0.332
I33 Acute and subacute endocarditis	0.668	0.332
T51 Toxic effect of alcohol	0.668	0.332
D22 Melanocytic naevi	0.668	0.332
M48 Other spondylopathies	0.667	0.333
M15 Polyarthrosis	0.667	0.333
B99-B99 Other infectious diseases	0.666	0.333
B85-B89 Pediculosis, acariasis and other infestations	0.666	0.333
B65-B83 Helminthiases	0.666	0.333
B50-B64 Protozoal diseases	0.666	0.333
B20-B24 Human immunodeficiency virus [HIV] disease	0.666	0.333
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.666	0.333
A75-A79 Rickettsioses	0.666	0.333
A70-A74 Other diseases caused by chlamydiae	0.666	0.333
A65-A69 Other spirochaetal diseases	0.666	0.333
A20-A28 Certain zoonotic bacterial diseases	0.666	0.333
A15-A19 Tuberculosis	0.666	0.333
S00-S09 Injuries to the head	0.666	0.334
D32.9 Meninges, unspecified	0.666	0.334
M21.2 Flexion deformity	0.665	0.334
T58 Toxic effect of carbon monoxide	0.665	0.335
M24.5 Contracture of joint	0.664	0.336
M71 Other bursopathies	0.664	0.336
M79.6 Pain in limb	0.663	0.337
D80-D89 Certain disorders involving the immune mechanism	0.663	0.337
I35.8 Other aortic valve disorders	0.662	0.338
S32.1 Fracture of sacrum	0.662	0.338
H25 Senile cataract	0.662	0.338
M46 Other inflammatory spondylopathies	0.661	0.339
D29.1 Prostate	0.661	0.339
C49 Malignant neoplasm of other connective and soft tissue	0.660	0.340
O29 Complications of anaesthesia during pregnancy	0.660	0.340
O28 Abnormal findings on antenatal screening of mother	0.660	0.340
O22 Venous complications in pregnancy	0.660	0.340
O25 Malnutrition in pregnancy	0.660	0.340
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.660	0.340
T81.7 Vascular complications following a procedure, not elsewhere classified	0.659	0.340
C02 Malignant neoplasm of other and unspecified parts of tongue	0.659	0.340
M62 Other disorders of muscle	0.659	0.340
B90-B94 Sequelae of infectious and parasitic diseases	0.659	0.341
M40-M43 Deforming dorsopathies	0.658	0.342
G61 Inflammatory polyneuropathy	0.657	0.343
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.657	0.343
H27 Other disorders of lens	0.657	0.343
T80 Complications following infusion, transfusion and therapeutic injection	0.657	0.343
Q38-Q45 Other congenital malformations of the digestive system	0.657	0.343
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.657	0.343
M10 Gout	0.657	0.343
M18.1 Other primary arthrosis of first carpometacarpal joint	0.657	0.343
S60-S69 Injuries to the wrist and hand	0.656	0.344
I22.8 Subsequent myocardial infarction of other sites	0.656	0.344
G82.5 Tetraplegia, unspecified	0.656	0.344
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.656	0.344
H05 Disorders of orbit	0.655	0.345
A50-A64 Infections with a predominantly sexual mode of transmission	0.654	0.345
I08.9 Multiple valve disease, unspecified	0.654	0.346
I08.8 Other multiple valve diseases	0.654	0.346
I08.2 Disorders of both aortic and tricuspid valves	0.654	0.346
O81 Single delivery by forceps and vacuum extractor	0.654	0.346
O23 Infections of genito-urinary tract in pregnancy	0.653	0.346
D11.9 Major salivary gland, unspecified	0.652	0.348
I20.1 Angina pectoris with documented spasm	0.652	0.348
M24.4 Recurrent dislocation and subluxation of joint	0.651	0.348
G72 Other myopathies	0.651	0.348
F03 Unspecified dementia	0.650	0.350
D36 Benign neoplasm of other and unspecified sites	0.649	0.351
Chapter XII Diseases of the skin and subcutaneous tissue	0.649	0.351
D12.5 Sigmoid colon	0.649	0.351
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.648	0.352
I61 Intracerebral haemorrhage	0.647	0.352
A49.0 Staphylococcal infection, unspecified	0.646	0.354
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.645	0.355
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.645	0.355
I60.5 Subarachnoid haemorrhage from vertebral artery	0.645	0.355
I60.4 Subarachnoid haemorrhage from basilar artery	0.645	0.355
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.645	0.355
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.645	0.355
F80-F89 Disorders of psychological development	0.644	0.356
I67.1 Cerebral aneurysm, nonruptured	0.644	0.356
H65-H75 Diseases of middle ear and mastoid	0.644	0.356
D00-D09 In situ neoplasms	0.644	0.356
F99-F99 Unspecified mental disorder	0.643	0.357
C55 Malignant neoplasm of uterus, part unspecified	0.643	0.357
G24 Dystonia	0.643	0.357
F01 Vascular dementia	0.642	0.358
I25.0 Atherosclerotic cardiovascular disease, so described	0.641	0.359
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.641	0.359
O02 Other abnormal products of conception	0.640	0.360
M79.1 Myalgia	0.640	0.360
T75 Effects of other external causes	0.640	0.360
T74 Maltreatment syndromes	0.640	0.360
T73 Effects of other deprivation	0.640	0.360
T70 Effects of air pressure and water pressure	0.640	0.360
T69 Other effects of reduced temperature	0.640	0.360
T67 Effects of heat and light	0.640	0.360
T71 Asphyxiation	0.640	0.360
T66 Unspecified effects of radiation	0.640	0.360
F60-F69 Disorders of adult personality and behaviour	0.640	0.360
A80-A89 Viral infections of the central nervous system	0.639	0.361
C07 Malignant neoplasm of parotid gland	0.639	0.361
T86 Failure and rejection of transplanted organs and tissues	0.639	0.361
M23.6 Other spontaneous disruption of ligament(s) of knee	0.638	0.362
M23.1 Discoid meniscus (congenital)	0.638	0.362
M23.0 Cystic meniscus	0.638	0.362
H25.8 Other senile cataract	0.638	0.362
C53.9 Cervix uteri, unspecified	0.638	0.362
I27 Other pulmonary heart diseases	0.638	0.362
F33.9 Recurrent depressive disorder, unspecified	0.637	0.363
D16.4 Bones of skull and face	0.637	0.363
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.636	0.364
A00-A09 Intestinal infectious diseases	0.636	0.364
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.635	0.365
M19.01 Primary arthrosis of other joints (Shoulder region)	0.635	0.365
S09 Other and unspecified injuries of head	0.634	0.366
H02.9 Disorder of eyelid, unspecified	0.634	0.366
S91.1 Open wound of toe(s) without damage to nail	0.633	0.367
H04 Disorders of lachrymal system	0.633	0.367
I45.8 Other specified conduction disorders	0.632	0.367
I45.4 Nonspecific intraventricular block	0.632	0.367
I45.3 Trifascicular block	0.632	0.367
I45.2 Bifascicular block	0.632	0.367
I45.0 Right fascicular block	0.632	0.367
F30 Manic episode	0.633	0.367
C57 Malignant neoplasm of other and unspecified female genital organs	0.632	0.367
C51 Malignant neoplasm of vulva	0.632	0.367
C58 Malignant neoplasm of placenta	0.632	0.367
C52 Malignant neoplasm of vagina	0.632	0.367
N18.1 Chronic kidney disease, stage 1	0.632	0.368
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.631	0.369
G62 Other polyneuropathies	0.630	0.370
M24.0 Loose body in joint	0.630	0.370
T15-T19 Effects of foreign body entering through natural orifice	0.629	0.370
S50-S59 Injuries to the elbow and forearm	0.629	0.371
C09 Malignant neoplasm of tonsil	0.629	0.371
C44.1 Skin of eyelid, including canthus	0.629	0.371
M23.30 Other meniscus derangements (Multiple sites)	0.628	0.372
H53-H54 Visual disturbances and blindness	0.628	0.372
S49 Other and unspecified injuries of shoulder and upper arm	0.627	0.372
H49 Paralytic strabismus	0.627	0.373
T21 Burn and corrosion of trunk	0.627	0.373
I67.2 Cerebral atherosclerosis	0.627	0.373
M05 Seropositive rheumatoid arthritis	0.627	0.373
O34.2 Maternal care due to uterine scar from previous surgery	0.626	0.374
S32.40 Fracture of acetabulum (closed)	0.625	0.375
S99 Other and unspecified injuries of ankle and foot	0.625	0.375
S98 Traumatic amputation of ankle and foot	0.625	0.375
S97 Crushing injury of ankle and foot	0.625	0.375
S96 Injury of muscle and tendon at ankle and foot level	0.625	0.375
S95 Injury of blood vessels at ankle and foot level	0.625	0.375
S94 Injury of nerves at ankle and foot level	0.625	0.375
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.625	0.375
S90 Superficial injury of ankle and foot	0.625	0.375
M24.9 Joint derangement, unspecified	0.624	0.376
M24.8 Other specific joint derangements, not elsewhere classified	0.624	0.376
M24.7 Protrusio acetabuli	0.624	0.376
M24.6 Ankylosis of joint	0.624	0.376
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.624	0.376
T11 Other injuries of upper limb, level unspecified	0.624	0.376
T09 Other injuries of spine and trunk, level unspecified	0.624	0.376
T12.X1 Fracture of lower limb, level unspecified (open)	0.624	0.376
T12.X0 Fracture of lower limb, level unspecified (closed)	0.624	0.376
T12 Fracture of lower limb, level unspecified	0.624	0.376
T10.X1 Fracture of upper limb, level unspecified (open)	0.624	0.376
T10.X0 Fracture of upper limb, level unspecified (closed)	0.624	0.376
T10 Fracture of upper limb, level unspecified	0.624	0.376
T08.X1 Fracture of spine, level unspecified (open)	0.624	0.376
T08.X0 Fracture of spine, level unspecified (closed)	0.624	0.376
T08 Fracture of spine, level unspecified	0.624	0.376
M75.8 Other shoulder lesions	0.623	0.377
O47 False labour	0.623	0.377
D12.4 Descending colon	0.623	0.377
M45 Ankylosing spondylitis	0.622	0.378
M24.16 Other articular cartilage disorders (Lower leg)	0.622	0.378
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.622	0.378
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.621	0.379
I51.6 Cardiovascular disease, unspecified	0.621	0.379
I51.5 Myocardial degeneration	0.621	0.379
I51.4 Myocarditis, unspecified	0.621	0.379

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations