TreeWAS – Variant ID: rs34308307

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter IX Diseases of the circulatory system	1.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
# Top node	1.000	0.000
I30-I52 Other forms of heart disease	0.999	0.001
M20-M25 Other joint disorders	0.998	0.002
M25.5 Pain in joint	0.998	0.002
M25 Other joint disorders, not elsewhere classified	0.997	0.003
M25.56 Pain in joint (Lower leg)	0.997	0.003
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.997	0.003
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.996	0.004
M15-M19 Arthrosis	0.995	0.005
T36-T50 Poisoning by drugs, medicaments and biological substances	0.995	0.005
I26 Pulmonary embolism	0.992	0.008
M16 Coxarthrosis [arthrosis of hip]	0.991	0.009
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.989	0.011
M16.1 Other primary coxarthrosis	0.989	0.011
Chapter I Certain infectious and parasitic diseases	0.976	0.024
I46 Cardiac arrest	0.966	0.034
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.961	0.039
I05-I09 Chronic rheumatic heart diseases	0.960	0.040
Chapter XX External causes of morbidity and mortality	0.949	0.051
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.948	0.052
M65-M68 Disorders of synovium and tendon	0.942	0.058
I50 Heart failure	0.938	0.062
I46.9 Cardiac arrest, unspecified	0.936	0.064
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.935	0.065
I70-I79 Diseases of arteries, arterioles and capillaries	0.931	0.069
M17 Gonarthrosis [arthrosis of knee]	0.928	0.072
M91-M94 Chondropathies	0.926	0.074
M25.59 Pain in joint (Site unspecified)	0.926	0.074
I08 Multiple valve diseases	0.925	0.075
T43.0 Tricyclic and tetracyclic antidepressants	0.920	0.080
A30-A49 Other bacterial diseases	0.917	0.083
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.914	0.086
I95-I99 Other and unspecified disorders of the circulatory system	0.911	0.089
I31 Other diseases of pericardium	0.907	0.093
M65 Synovitis and tenosynovitis	0.892	0.108
B25-B34 Other viral diseases	0.890	0.110
Y52 Agents primarily affecting the cardiovascular system	0.889	0.111
Chapter IV Endocrine, nutritional and metabolic diseases	0.888	0.112
S10-S19 Injuries to the neck	0.878	0.122
T39.1 4-Aminophenol derivatives	0.877	0.123
I45 Other conduction disorders	0.872	0.128
M16.7 Other secondary coxarthrosis	0.872	0.128
E65-E68 Obesity and other hyperalimentation	0.869	0.131
I20-I25 Ischaemic heart diseases	0.863	0.137
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.863	0.137
A41 Other septicaemia	0.858	0.142
I49 Other cardiac arrhythmias	0.858	0.142
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.857	0.143
I50.1 Left ventricular failure	0.855	0.145
E66 Obesity	0.853	0.147
M17.1 Other primary gonarthrosis	0.853	0.147
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.851	0.149
I36 Nonrheumatic tricuspid valve disorders	0.851	0.149
M65.9 Synovitis and tenosynovitis, unspecified	0.851	0.149
S60-S69 Injuries to the wrist and hand	0.848	0.152
I27 Other pulmonary heart diseases	0.845	0.155
M86-M90 Other osteopathies	0.843	0.157
Y52.4 Angiotensin-converting-enzyme inhibitors	0.842	0.158
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.842	0.158
Chapter VI Diseases of the nervous system	0.841	0.159
S70-S79 Injuries to the hip and thigh	0.841	0.159
I08.0 Disorders of both mitral and aortic valves	0.837	0.163
I24 Other acute ischaemic heart diseases	0.835	0.165
Chapter VII Diseases of the eye and adnexa	0.834	0.166
I95 Hypotension	0.833	0.167
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.832	0.168
E66.8 Other obesity	0.831	0.169
Y40 Systemic antibiotics	0.828	0.172
M23 Internal derangement of knee	0.827	0.173
M25.55 Pain in joint (Pelvic region and thigh)	0.826	0.174
I31.3 Pericardial effusion (noninflammatory)	0.818	0.182
B07 Viral warts	0.817	0.183
M92 Other juvenile osteochondrosis	0.816	0.184
M24 Other specific joint derangements	0.812	0.188
B34 Viral infection of unspecified site	0.808	0.192
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.805	0.195
M60-M63 Disorders of muscles	0.804	0.196
M34 Systemic sclerosis	0.800	0.200
I95.2 Hypotension due to drugs	0.800	0.200
I35 Nonrheumatic aortic valve disorders	0.800	0.200
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.799	0.201
I24.9 Acute ischaemic heart disease, unspecified	0.798	0.202
H10-H13 Disorders of conjunctiva	0.795	0.205
G00-G09 Inflammatory diseases of the central nervous system	0.793	0.207
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.793	0.207
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.792	0.208
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.791	0.209
M16.0 Primary coxarthrosis, bilateral	0.789	0.211
I07 Rheumatic tricuspid valve diseases	0.788	0.212
M25.9 Joint disorder, unspecified	0.787	0.213
I78 Diseases of capillaries	0.786	0.214
T40.2 Other opioids	0.785	0.215
I45.1 Other and unspecified right bundle-branch block	0.785	0.215
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.777	0.223
I72 Other aneurysm	0.777	0.223
W00-W19 Falls	0.775	0.225
M65.4 Radial styloid tenosynovitis [de Quervain]	0.775	0.225
Y41 Other systemic anti-infectives and antiparasitics	0.774	0.226
T39.0 Salicylates	0.771	0.229
M23.8 Other internal derangements of knee	0.771	0.229
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.770	0.230
M94 Other disorders of cartilage	0.770	0.230
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.769	0.231
M31 Other necrotising vasculopathies	0.769	0.231
H46-H48 Disorders of optic nerve and visual pathways	0.768	0.232
I49.9 Cardiac arrhythmia, unspecified	0.766	0.234
M25.51 Pain in joint (Shoulder region)	0.763	0.237
M17.3 Other posttraumatic gonarthrosis	0.763	0.237
S64 Injury of nerves at wrist and hand level	0.761	0.239
H11 Other disorders of conjunctiva	0.761	0.239
Chapter XXI Factors influencing health status and contact with health services	0.759	0.241
M70-M79 Other soft tissue disorders	0.757	0.243
Y00-Y09 Assault	0.754	0.246
B02 Zoster [herpes zoster]	0.752	0.248
I46.0 Cardiac arrest with successful resuscitation	0.751	0.249
T00-T07 Injuries involving multiple body regions	0.750	0.250
M25.57 Pain in joint (Ankle and foot)	0.750	0.250
I50.0 Congestive heart failure	0.750	0.250
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.749	0.251
B34.9 Viral infection, unspecified	0.749	0.251
T93 Sequelae of injuries of lower limb	0.747	0.253
A49 Bacterial infection of unspecified site	0.746	0.254
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.745	0.255
X40-X49 Accidental poisoning by and exposure to noxious substances	0.745	0.255
G20-G26 Extrapyramidal and movement disorders	0.744	0.256
M67 Other disorders of synovium and tendon	0.744	0.256
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.742	0.258
I50.9 Heart failure, unspecified	0.741	0.259
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.741	0.259
G90-G99 Other disorders of the nervous system	0.740	0.260
M16.5 Other posttraumatic coxarthrosis	0.738	0.262
A41.8 Other specified septicaemia	0.737	0.263
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.737	0.263
I74 Arterial embolism and thrombosis	0.736	0.264
T46 Poisoning by agents primarily affecting the cardiovascular system	0.735	0.265
D69 Purpura and other haemorrhagic conditions	0.734	0.266
A41.0 Septicaemia due to Staphylococcus aureus	0.733	0.267
T20-T25 Burns and corrosions of external body surface, specified by site	0.732	0.268
M25.0 Haemarthrosis	0.729	0.271
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.728	0.272
X60-X84 Intentional self-harm	0.725	0.274
I71 Aortic aneurysm and dissection	0.725	0.275
Y40.9 Systemic antibiotic, unspecified	0.725	0.275
M25.3 Other instability of joint	0.725	0.275
Y51 Drugs primarily affecting the autonomic nervous system	0.724	0.276
I30 Acute pericarditis	0.723	0.277
M25.54 Pain in joint (Hand)	0.722	0.278
Y46 Antiepileptics and anti-Parkinsonism drugs	0.721	0.279
X58-X59 Accidental exposure to other and unspecified factors	0.720	0.280
T43.5 Other and unspecified antipsychotics and neuroleptics	0.720	0.280
I22 Subsequent myocardial infarction	0.720	0.280
S71 Open wound of hip and thigh	0.720	0.280
I31.9 Disease of pericardium, unspecified	0.719	0.281
Z60 Problems related to social environment	0.718	0.282
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.717	0.283
I44 Atrioventricular and left bundle-branch block	0.717	0.283
I00-I02 Acute rheumatic fever	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
A39 Meningococcal infection	0.717	0.283
I08.1 Disorders of both mitral and tricuspid valves	0.716	0.284
I52 Other heart disorders in diseases classified elsewhere	0.716	0.284
I48 Atrial fibrillation and flutter	0.716	0.284
I43 Cardiomyopathy in diseases classified elsewhere	0.716	0.284
I41 Myocarditis in diseases classified elsewhere	0.716	0.284
I40 Acute myocarditis	0.716	0.284
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.716	0.284
I32 Pericarditis in diseases classified elsewhere	0.716	0.284
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.716	0.284
M33 Dermatopolymyositis	0.716	0.284
M32 Systemic lupus erythematosus	0.716	0.284
M30 Polyarteritis nodosa and related conditions	0.716	0.284
Y60-Y69 Misadventures to patients during surgical and medical care	0.715	0.284
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.715	0.285
M25.58 Pain in joint (Other)	0.715	0.285
M25.53 Pain in joint (Forearm)	0.715	0.285
M25.2 Flail joint	0.715	0.285
M25.1 Fistula of joint	0.715	0.285
I28 Other diseases of pulmonary vessels	0.714	0.285
Y48 Anaesthetics and therapeutic gases	0.714	0.286
T33-T35 Frostbite	0.714	0.286
T26-T28 Burns and corrosions confined to eye and internal organs	0.714	0.286
M15 Polyarthrosis	0.713	0.286
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.713	0.287
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.713	0.287
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.713	0.287
T41 Poisoning by anaesthetics and therapeutic gases	0.713	0.287
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.713	0.287
T36 Poisoning by systemic antibiotics	0.713	0.287
M93 Other osteochondropathies	0.713	0.287
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.711	0.289
A41.5 Septicaemia due to other Gram-negative organisms	0.711	0.289
M16.6 Other secondary coxarthrosis, bilateral	0.711	0.289
M16.4 Posttraumatic coxarthrosis, bilateral	0.711	0.289
M16.2 Coxarthrosis resulting from dysplasia, bilateral	0.711	0.289
M00-M03 Infectious arthropathies	0.709	0.291
S12 Fracture of neck	0.709	0.291
I70 Atherosclerosis	0.709	0.291
I37 Pulmonary valve disorders	0.709	0.291
T66-T78 Other and unspecified effects of external causes	0.706	0.294
I77 Other disorders of arteries and arterioles	0.706	0.294
S20-S29 Injuries to the thorax	0.706	0.294
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.705	0.294
Z60.2 Living alone	0.705	0.295
H47 Other disorders of optic [2nd] nerve and visual pathways	0.703	0.297
Y53 Agents primarily affecting the gastro-intestinal system	0.703	0.297
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.702	0.298
B25 Cytomegaloviral disease	0.701	0.298
M17.9 Gonarthrosis, unspecified	0.701	0.299
M92.6 Juvenile osteochondrosis of tarsus	0.700	0.300
B99-B99 Other infectious diseases	0.700	0.300
B90-B94 Sequelae of infectious and parasitic diseases	0.700	0.300
B85-B89 Pediculosis, acariasis and other infestations	0.700	0.300
B65-B83 Helminthiases	0.700	0.300
B50-B64 Protozoal diseases	0.700	0.300
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.700	0.300
A75-A79 Rickettsioses	0.700	0.300
A70-A74 Other diseases caused by chlamydiae	0.700	0.300
A65-A69 Other spirochaetal diseases	0.700	0.300
A20-A28 Certain zoonotic bacterial diseases	0.700	0.300
A15-A19 Tuberculosis	0.700	0.300
T90 Sequelae of injuries of head	0.699	0.301
I35.2 Aortic (valve) stenosis with insufficiency	0.698	0.302
I27.2 Other secondary pulmonary hypertension	0.696	0.304
M21 Other acquired deformities of limbs	0.696	0.304
M87 Osteonecrosis	0.695	0.304
B01 Varicella [chickenpox]	0.695	0.305
Y44 Agents primarily affecting blood constituents	0.695	0.305
S66 Injury of muscle and tendon at wrist and hand level	0.695	0.305
G00 Bacterial meningitis, not elsewhere classified	0.695	0.305
B20-B24 Human immunodeficiency virus [HIV] disease	0.694	0.305
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.694	0.306
I45.2 Bifascicular block	0.693	0.307
H11.3 Conjunctival haemorrhage	0.693	0.307
W13 Fall from, out of or through building or structure	0.692	0.308
I46.1 Sudden cardiac death, so described	0.692	0.308
B00 Herpesviral [herpes simplex] infections	0.691	0.309
I47 Paroxysmal tachycardia	0.690	0.310
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.689	0.311
T39.4 Antirheumatics, not elsewhere classified	0.689	0.311
T39.2 Pyrazolone derivatives	0.689	0.311
I09 Other rheumatic heart diseases	0.688	0.312
I06 Rheumatic aortic valve diseases	0.688	0.312
H11.4 Other conjunctival vascular disorders and cysts	0.688	0.312
I78.0 Hereditary haemorrhagic telangiectasia	0.688	0.312
G70-G73 Diseases of myoneural junction and muscle	0.687	0.313
I24.8 Other forms of acute ischaemic heart disease	0.685	0.315
G20 Parkinson's disease	0.684	0.316
V40-V49 Car occupant injured in transport accident	0.683	0.317
M23.4 Loose body in knee	0.683	0.317
M25.52 Pain in joint (Upper arm)	0.683	0.317
I49.3 Ventricular premature depolarisation	0.682	0.318
I99 Other and unspecified disorders of circulatory system	0.682	0.318
Z36 Antenatal screening	0.681	0.319
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.681	0.319
Y35-Y36 Legal intervention and operations of war	0.680	0.320
Y10-Y34 Event of undetermined intent	0.680	0.320
X85-X99 Assault	0.680	0.320
X30-X39 Exposure to forces of nature	0.680	0.320
X10-X19 Contact with heat and hot substances	0.680	0.320
X00-X09 Exposure to smoke, fire and flames	0.680	0.320
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.680	0.320
W75-W84 Other accidental threats to breathing	0.680	0.320
W65-W74 Accidental drowning and submersion	0.680	0.320
V98-V99 Other and unspecified transport accidents	0.680	0.320
V95-V97 Air and space transport accidents	0.680	0.320
V90-V94 Water transport accidents	0.680	0.320
V70-V79 Bus occupant injured in transport accident	0.680	0.320
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.680	0.320
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.680	0.320
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.680	0.320
V01-V09 Pedestrian injured in transport accident	0.680	0.320
T43.9 Psychotropic drug, unspecified	0.680	0.320
T43.8 Other psychotropic drugs, not elsewhere classified	0.680	0.320
T43.6 Psychostimulants with abuse potential	0.680	0.320
T43.4 Butyrophenone and thioxanthene neuroleptics	0.680	0.320
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.680	0.320
T43.3 Phenothiazine antipsychotics and neuroleptics	0.679	0.321
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.679	0.321
X20-X29 Contact with venomous animals and plants	0.678	0.322
T45.5 Anticoagulants	0.678	0.322
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.675	0.325
M25.50 Pain in joint (Multiple sites)	0.675	0.325
I33 Acute and subacute endocarditis	0.675	0.325
I98 Other disorders of circulatory system in diseases classified elsewhere	0.674	0.326
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)	0.674	0.326
M24.8 Other specific joint derangements, not elsewhere classified	0.673	0.327
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.672	0.328
S19 Other and unspecified injuries of neck	0.672	0.328
A80-A89 Viral infections of the central nervous system	0.671	0.329
Y59 Other and unspecified vaccines and biological substances	0.670	0.330
Y58 Bacterial vaccines	0.670	0.330
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.670	0.330
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.670	0.330
Y50 Central nervous system stimulants, not elsewhere classified	0.670	0.330
Y49 Psychotropic drugs, not elsewhere classified	0.670	0.330
Y47 Sedatives, hypnotics and antianxiety drugs	0.670	0.330
E66.9 Obesity, unspecified	0.670	0.330
Y40.1 Cefalosporins and other -lactam antibiotics	0.670	0.330
D68 Other coagulation defects	0.668	0.332
W07 Fall involving chair	0.668	0.332
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.667	0.332
S65 Injury of blood vessels at wrist and hand level	0.667	0.333
X50-X57 Overexertion, travel and privation	0.666	0.334
M89 Other disorders of bone	0.666	0.334
I85 Oesophageal varices	0.665	0.334
M17.4 Other secondary gonarthrosis, bilateral	0.665	0.335
M17.2 Posttraumatic gonarthrosis, bilateral	0.665	0.335
I07.1 Tricuspid insufficiency	0.665	0.335
M91 Juvenile osteochondrosis of hip and pelvis	0.664	0.336
E65 Localised adiposity	0.663	0.337
I08.9 Multiple valve disease, unspecified	0.663	0.337
I08.8 Other multiple valve diseases	0.663	0.337
I08.2 Disorders of both aortic and tricuspid valves	0.663	0.337
E66.0 Obesity due to excess calories	0.663	0.337
S14 Injury of nerves and spinal cord at neck level	0.662	0.337
S69 Other and unspecified injuries of wrist and hand	0.662	0.338
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.661	0.339
E10-E14 Diabetes mellitus	0.660	0.340
M92.7 Juvenile osteochondrosis of metatarsus	0.659	0.341
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.659	0.341
W50-W64 Exposure to animate mechanical forces	0.659	0.341
S90-S99 Injuries to the ankle and foot	0.658	0.342
M77 Other enthesopathies	0.658	0.342
A48 Other bacterial diseases, not elsewhere classified	0.658	0.342
A44 Bartonellosis	0.658	0.342
A43 Nocardiosis	0.658	0.342
A42 Actinomycosis	0.658	0.342
A37 Whooping cough	0.658	0.342
A36 Diphtheria	0.658	0.342
A32 Listeriosis	0.658	0.342
A31 Infection due to other mycobacteria	0.658	0.342
A30 Leprosy [Hansen's disease]	0.658	0.342
A38 Scarlet fever	0.658	0.342
A35 Other tetanus	0.658	0.342
A34 Obstetrical tetanus	0.658	0.342
A33 Tetanus neonatorum	0.658	0.342
A41.1 Septicaemia due to other specified staphylococcus	0.657	0.343
M16.3 Other dysplastic coxarthrosis	0.657	0.343
Y52.3 Coronary vasodilators, not elsewhere classified	0.656	0.344
S64.4 Injury of digital nerve of other finger	0.656	0.344
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified	0.655	0.345
B06 Rubella [German measles]	0.655	0.345
B05 Measles	0.655	0.345
B09 Unspecified viral infection characterised by skin and mucous membrane lesions	0.655	0.345
B04 Monkeypox	0.655	0.345
B03 Smallpox	0.655	0.345
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.655	0.345
A50-A64 Infections with a predominantly sexual mode of transmission	0.655	0.345
S32 Fracture of lumbar spine and pelvis	0.654	0.346
I51 Complications and ill-defined descriptions of heart disease	0.654	0.346
Y52.1 Calcium-channel blockers	0.652	0.348
T45.1 Antineoplastic and immunosuppressive drugs	0.652	0.348
I31.8 Other specified diseases of pericardium	0.650	0.349
I31.2 Haemopericardium, not elsewhere classified	0.650	0.349
I31.1 Chronic constrictive pericarditis	0.650	0.349
I31.0 Chronic adhesive pericarditis	0.650	0.349
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.650	0.350
M25.4 Effusion of joint	0.650	0.350
Chapter XII Diseases of the skin and subcutaneous tissue	0.649	0.351
S68 Traumatic amputation of wrist and hand	0.649	0.351
I72.0 Aneurysm of carotid artery	0.648	0.352
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.648	0.352
E66.2 Extreme obesity with alveolar hypoventilation	0.648	0.352
M17.0 Primary gonarthrosis, bilateral	0.647	0.353
M67.8 Other specified disorders of synovium and tendon	0.647	0.353
M25.7 Osteophyte	0.646	0.354
I87 Other disorders of veins	0.646	0.354
S50-S59 Injuries to the elbow and forearm	0.644	0.356
M94.8 Other specified disorders of cartilage	0.644	0.356
D69.3 Idiopathic thrombocytopenic purpura	0.644	0.356
B15-B19 Viral hepatitis	0.643	0.357
M66 Spontaneous rupture of synovium and tendon	0.642	0.357
T45.0 Antiallergic and antiemetic drugs	0.642	0.358
I27.9 Pulmonary heart disease, unspecified	0.642	0.358
I49.1 Atrial premature depolarisation	0.641	0.359
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.641	0.359
G01 Meningitis in bacterial diseases classified elsewhere	0.639	0.361
M65.2 Calcific tendinitis	0.639	0.361
M65.1 Other infective (teno)synovitis	0.639	0.361
M65.0 Abscess of tendon sheath	0.639	0.361
W10 Fall on and from stairs and steps	0.639	0.361
V10-V19 Pedal cyclist injured in transport accident	0.639	0.361
I49.5 Sick sinus syndrome	0.639	0.361
M17.5 Other secondary gonarthrosis	0.639	0.361
I74.5 Embolism and thrombosis of iliac artery	0.639	0.361
B33 Other viral diseases, not elsewhere classified	0.638	0.362
B30 Viral conjunctivitis	0.638	0.362
B27 Infectious mononucleosis	0.638	0.362
B26 Mumps	0.638	0.362
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.637	0.363
Y52.8 Antivaricose drugs, including sclerosing agents	0.637	0.363
Y52.7 Peripheral vasodilators	0.637	0.363
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.637	0.363
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.637	0.363
Chapter XXII Codes for special purposes	0.637	0.363
M25.96 Joint disorder, unspecified (Lower leg)	0.637	0.363
S79 Other and unspecified injuries of hip and thigh	0.637	0.363
S36 Injury of intra-abdominal organs	0.635	0.365
V20-V29 Motorcycle rider injured in transport accident	0.635	0.365
M86 Osteomyelitis	0.634	0.366
H40-H42 Glaucoma	0.634	0.366
Z34 Supervision of normal pregnancy	0.633	0.367
W13.9 Unspecified place	0.633	0.367
M65.8 Other synovitis and tenosynovitis	0.633	0.367
S71.1 Open wound of thigh	0.633	0.367
M31.3 Wegener's granulomatosis	0.633	0.367
M34.9 Systemic sclerosis, unspecified	0.633	0.367
T51 Toxic effect of alcohol	0.633	0.367
I35.0 Aortic (valve) stenosis	0.632	0.368
Z36.8 Other antenatal screening	0.632	0.368
S60 Superficial injury of wrist and hand	0.631	0.368
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.631	0.368
M60 Myositis	0.631	0.369
S10 Superficial injury of neck	0.631	0.369
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.630	0.369
H47.3 Other disorders of optic disk	0.630	0.370
S17 Crushing injury of neck	0.629	0.371
S15 Injury of blood vessels at neck level	0.629	0.371
S11 Open wound of neck	0.629	0.371
S18 Traumatic amputation at neck level	0.629	0.371
S16 Injury of muscle and tendon at neck level	0.629	0.371
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.629	0.371
I27.0 Primary pulmonary hypertension	0.629	0.371
A49.8 Other bacterial infections of unspecified site	0.627	0.373
G03 Meningitis due to other and unspecified causes	0.626	0.374
A40 Streptococcal septicaemia	0.626	0.374
D55-D59 Haemolytic anaemias	0.626	0.374
T79-T79 Certain early complications of trauma	0.625	0.374
I45.4 Nonspecific intraventricular block	0.625	0.375
I45.3 Trifascicular block	0.625	0.375
I45.0 Right fascicular block	0.625	0.375
T42.0 Hydantoin derivatives	0.624	0.375
Y57 Other and unspecified drugs and medicaments	0.624	0.376
I45.8 Other specified conduction disorders	0.623	0.377
E67 Other hyperalimentation	0.623	0.377
E68 Sequelae of hyperalimentation	0.623	0.377
M22 Disorders of patella	0.623	0.377
M25.6 Stiffness of joint, not elsewhere classified	0.622	0.377
E50-E64 Other nutritional deficiencies	0.622	0.378
V80-V89 Other land transport accidents	0.622	0.378
I72.3 Aneurysm of iliac artery	0.622	0.378
W20-W49 Exposure to inanimate mechanical forces	0.621	0.379
S72 Fracture of femur	0.620	0.380
M62 Other disorders of muscle	0.620	0.380
B02.9 Zoster without complication	0.619	0.381
I23 Certain current complications following acute myocardial infarction	0.619	0.381
T95 Sequelae of burns, corrosions and frostbite	0.619	0.381
T94 Sequelae of injuries involving multiple and unspecified body regions	0.619	0.381
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.619	0.381
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.619	0.381
I45.5 Other specified heart block	0.618	0.381
M24.2 Disorder of ligament	0.617	0.382
G06 Intracranial and intraspinal abscess and granuloma	0.617	0.382
Z58 Problems related to physical environment	0.617	0.383
I27.8 Other specified pulmonary heart diseases	0.617	0.383
Z36.9 Antenatal screening, unspecified	0.616	0.384
M40-M43 Deforming dorsopathies	0.616	0.384
M34.8 Other forms of systemic sclerosis	0.616	0.384
A41.4 Septicaemia due to anaerobes	0.615	0.384
A41.3 Septicaemia due to Haemophilus influenzae	0.615	0.384
A41.2 Septicaemia due to unspecified staphylococcus	0.615	0.384
I49.2 Junctional premature depolarisation	0.615	0.385
T91 Sequelae of injuries of neck and trunk	0.615	0.385
Y43 Primarily systemic agents	0.615	0.385
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.614	0.385
T40.8 Lysergide [LSD]	0.614	0.385
T40.7 Cannabis (derivatives)	0.614	0.385
T40.6 Other and unspecified narcotics	0.614	0.385
T40.5 Cocaine	0.614	0.385
T40.3 Methadone	0.614	0.385
T40.1 Heroin	0.614	0.385
T40.0 Opium	0.614	0.385
D69.5 Secondary thrombocytopenia	0.614	0.386
S31 Open wound of abdomen, lower back and pelvis	0.614	0.386
I77.1 Stricture of artery	0.613	0.387
T93.9 Sequelae of unspecified injury of lower limb	0.613	0.387
A00-A09 Intestinal infectious diseases	0.612	0.388
E66.1 Drug-induced obesity	0.612	0.388
H46 Optic neuritis	0.612	0.388
I44.1 Atrioventricular block, second degree	0.612	0.388
G91 Hydrocephalus	0.611	0.389
T93.1 Sequelae of fracture of femur	0.611	0.389
G96 Other disorders of central nervous system	0.611	0.389
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.610	0.390
I36.8 Other nonrheumatic tricuspid valve disorders	0.610	0.390
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.610	0.390
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.610	0.390
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)	0.610	0.390
M65.98 Synovitis and tenosynovitis, unspecified (Other)	0.610	0.390
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)	0.610	0.390
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)	0.610	0.390
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)	0.610	0.390
H10 Conjunctivitis	0.610	0.390
Y40.0 Penicillins	0.609	0.391
G09 Sequelae of inflammatory diseases of central nervous system	0.608	0.391
G93 Other disorders of brain	0.608	0.392
I49.4 Other and unspecified premature depolarisation	0.607	0.392
T90.9 Sequelae of unspecified injury of head	0.606	0.393

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations