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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs116869561
log Bayes Factor = 11.863
Chromosome 13   position 91,230,333  (GRCh37) Explore rs116869561 on Ensembl!
Variant rs116869561 is part of Cluster X0188

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
0.998 0.002 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.998 0.002 0.000
J40-J47 Chronic lower respiratory diseases
0.995 0.005 0.000
M50-M54 Other dorsopathies
0.994 0.006 0.000
J44 Other chronic obstructive pulmonary disease
0.994 0.006 0.000
M45-M49 Spondylopathies
0.993 0.007 0.000
M54 Dorsalgia
0.989 0.011 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.988 0.012 0.000
I30-I52 Other forms of heart disease
0.985 0.015 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.984 0.016 0.000
M54.9 Dorsalgia, unspecified
0.984 0.016 0.000
E70-E90 Metabolic disorders
0.981 0.019 0.000
M47 Spondylosis
0.980 0.020 0.000
J95-J99 Other diseases of the respiratory system
0.978 0.022 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.974 0.026 0.000
S60-S69 Injuries to the wrist and hand
0.974 0.026 0.000
I95 Hypotension
0.968 0.032 0.000
Chapter V Mental and behavioural disorders
0.968 0.032 0.000
S40-S49 Injuries to the shoulder and upper arm
0.968 0.032 0.000
Chapter VI Diseases of the nervous system
0.965 0.035 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.953 0.047 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.952 0.048 0.000
I95.1 Orthostatic hypotension
0.951 0.049 0.000
I45 Other conduction disorders
0.948 0.052 0.000
E20-E35 Disorders of other endocrine glands
0.943 0.057 0.000
J98 Other respiratory disorders
0.942 0.058 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.941 0.059 0.000
S20-S29 Injuries to the thorax
0.935 0.065 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.934 0.066 0.000
M47.9 Spondylosis, unspecified
0.933 0.067 0.000
G40-G47 Episodic and paroxysmal disorders
0.933 0.067 0.000
S00-S09 Injuries to the head
0.929 0.071 0.000
I05-I09 Chronic rheumatic heart diseases
0.924 0.076 0.000
E86 Volume depletion
0.923 0.077 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.923 0.077 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.920 0.080 0.000
S61 Open wound of wrist and hand
0.918 0.082 0.000
D50-D53 Nutritional anaemias
0.916 0.084 0.000
I51 Complications and ill-defined descriptions of heart disease
0.915 0.085 0.000
G62 Other polyneuropathies
0.911 0.089 0.000
J98.1 Pulmonary collapse
0.908 0.092 0.000
E89.0 Postprocedural hypothyroidism
0.908 0.092 0.000
Chapter XXI Factors influencing health status and contact with health services
0.902 0.098 0.000
G62.9 Polyneuropathy, unspecified
0.899 0.101 0.000
S61.0 Open wound of finger(s) without damage to nail
0.899 0.101 0.000
M70-M79 Other soft tissue disorders
0.898 0.102 0.000
J47 Bronchiectasis
0.898 0.102 0.000
J90-J94 Other diseases of pleura
0.897 0.103 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.891 0.109 0.000
S00 Superficial injury of head
0.888 0.112 0.000
D50 Iron deficiency anaemia
0.884 0.116 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.883 0.117 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.883 0.117 0.000
M47.8 Other spondylosis
0.882 0.118 0.000
S42 Fracture of shoulder and upper arm
0.881 0.119 0.000
S64 Injury of nerves at wrist and hand level
0.880 0.120 0.000
F99-F99 Unspecified mental disorder
0.879 0.121 0.000
M51 Other intervertebral disk disorders
0.876 0.124 0.000
S40 Superficial injury of shoulder and upper arm
0.866 0.134 0.000
D50.8 Other iron deficiency anaemias
0.866 0.134 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.865 0.135 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.861 0.139 0.000
G40 Epilepsy
0.857 0.143 0.000
M48 Other spondylopathies
0.857 0.143 0.000
M86-M90 Other osteopathies
0.856 0.143 0.000
E10-E14 Diabetes mellitus
0.856 0.144 0.000
E00-E07 Disorders of thyroid gland
0.854 0.146 0.000
I45.9 Conduction disorder, unspecified
0.850 0.150 0.000
M80-M85 Disorders of bone density and structure
0.846 0.154 0.000
I50 Heart failure
0.845 0.155 0.000
Chapter II Neoplasms
0.844 0.156 0.000
I95.9 Hypotension, unspecified
0.843 0.157 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.840 0.160 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.838 0.162 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.837 0.163 0.000
Z72 Problems related to lifestyle
0.836 0.164 0.000
I51.4 Myocarditis, unspecified
0.835 0.165 0.000
I08 Multiple valve diseases
0.833 0.167 0.000
E29 Testicular dysfunction
0.832 0.168 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.829 0.171 0.000
M60-M63 Disorders of muscles
0.828 0.172 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.828 0.172 0.000
E27 Other disorders of adrenal gland
0.828 0.172 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.828 0.172 0.000
I20-I25 Ischaemic heart diseases
0.827 0.173 0.000
M45 Ankylosing spondylitis
0.824 0.176 0.000
Z74 Problems related to care-provider dependency
0.823 0.177 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.823 0.177 0.000
E10 Insulin-dependent diabetes mellitus
0.822 0.178 0.000
G40.9 Epilepsy, unspecified
0.821 0.179 0.000
I46 Cardiac arrest
0.820 0.180 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.818 0.182 0.000
F99 Mental disorder, not otherwise specified
0.816 0.184 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.812 0.188 0.000
Z72.0 Tobacco use
0.811 0.189 0.000
M47.2 Other spondylosis with radiculopathy
0.810 0.190 0.000
M05-M14 Inflammatory polyarthropathies
0.808 0.192 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.808 0.192 0.000
S64.4 Injury of digital nerve of other finger
0.807 0.193 0.000
T79-T79 Certain early complications of trauma
0.807 0.193 0.000
I45.6 Preexcitation syndrome
0.805 0.195 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.801 0.199 0.000
M51.2 Other specified intervertebral disk displacement
0.800 0.200 0.000
M47.82 Other spondylosis (Cervical region)
0.799 0.201 0.000
Z73 Problems related to life-management difficulty
0.797 0.203 0.000
I99 Other and unspecified disorders of circulatory system
0.796 0.204 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.794 0.206 0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified
0.794 0.206 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.792 0.208 0.000
M54.6 Pain in thoracic spine
0.790 0.210 0.000
S10-S19 Injuries to the neck
0.790 0.210 0.000
E10.9 Without complications
0.789 0.211 0.000
S42.3 Fracture of shaft of humerus
0.788 0.212 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.788 0.212 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.786 0.214 0.000
S27 Injury of other and unspecified intrathoracic organs
0.785 0.215 0.000
I31 Other diseases of pericardium
0.784 0.216 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.783 0.217 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.783 0.217 0.000
M89 Other disorders of bone
0.782 0.218 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.782 0.218 0.000
M54.4 Lumbago with sciatica
0.781 0.219 0.000
C51-C58 Malignant neoplasms of female genital organs
0.779 0.221 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.779 0.221 0.000
Chapter XX External causes of morbidity and mortality
0.779 0.221 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.775 0.225 0.000
I47 Paroxysmal tachycardia
0.773 0.227 0.000
J43 Emphysema
0.773 0.227 0.000
I45.8 Other specified conduction disorders
0.772 0.228 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.771 0.229 0.000
I22 Subsequent myocardial infarction
0.770 0.230 0.000
I73 Other peripheral vascular diseases
0.770 0.230 0.000
F60-F69 Disorders of adult personality and behaviour
0.770 0.230 0.000
I77 Other disorders of arteries and arterioles
0.765 0.235 0.000
J60-J70 Lung diseases due to external agents
0.764 0.236 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.764 0.236 0.000
S00.7 Multiple superficial injuries of head
0.762 0.238 0.000
M77 Other enthesopathies
0.762 0.238 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.761 0.239 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.761 0.239 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.761 0.239 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.760 0.240 0.000
M40-M43 Deforming dorsopathies
0.759 0.241 0.000
I51.6 Cardiovascular disease, unspecified
0.759 0.241 0.000
J93 Pneumothorax
0.758 0.242 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.758 0.242 0.000
E40-E46 Malnutrition
0.758 0.242 0.000
F10.1 Harmful use
0.757 0.243 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.757 0.243 0.000
M54.5 Low back pain
0.757 0.243 0.000
C56 Malignant neoplasm of ovary
0.756 0.244 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.756 0.244 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.755 0.245 0.000
E29.1 Testicular hypofunction
0.753 0.247 0.000
S80-S89 Injuries to the knee and lower leg
0.751 0.249 0.000
I37 Pulmonary valve disorders
0.750 0.250 0.000
E73 Lactose intolerance
0.750 0.250 0.000
M48.0 Spinal stenosis
0.750 0.250 0.000
E88 Other metabolic disorders
0.748 0.252 0.000
I33 Acute and subacute endocarditis
0.748 0.252 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.748 0.252 0.000
M91-M94 Chondropathies
0.746 0.254 0.000
Z74.0 Reduced mobility
0.746 0.254 0.000
M65-M68 Disorders of synovium and tendon
0.745 0.255 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.744 0.256 0.000
G41 Status epilepticus
0.744 0.256 0.000
G43 Migraine
0.743 0.257 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.742 0.257 0.000
J95.8 Other postprocedural respiratory disorders
0.741 0.259 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.740 0.259 0.000
Chapter XXII Codes for special purposes
0.740 0.260 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.740 0.260 0.000
J42 Unspecified chronic bronchitis
0.738 0.262 0.000
I45.2 Bifascicular block
0.738 0.262 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.736 0.264 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.736 0.264 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.736 0.264 0.000
I07 Rheumatic tricuspid valve diseases
0.735 0.265 0.000
M54.1 Radiculopathy
0.735 0.265 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.734 0.266 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.734 0.266 0.000
M72 Fibroblastic disorders
0.734 0.266 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.733 0.267 0.000
S42.1 Fracture of scapula
0.732 0.268 0.000
S09 Other and unspecified injuries of head
0.730 0.270 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.728 0.272 0.000
S05 Injury of eye and orbit
0.728 0.272 0.000
S00.1 Contusion of eyelid and periocular area
0.727 0.273 0.000
Chapter VIII Diseases of the ear and mastoid process
0.727 0.273 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.726 0.274 0.000
J94 Other pleural conditions
0.724 0.276 0.000
J91 Pleural effusion in conditions classified elsewhere
0.724 0.276 0.000
S42.30 Fracture of shaft of humerus (closed)
0.722 0.278 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.721 0.279 0.000
Q60-Q64 Congenital malformations of the urinary system
0.720 0.280 0.000
S20 Superficial injury of thorax
0.720 0.280 0.000
M47.1 Other spondylosis with myelopathy
0.720 0.280 0.000
E23 Hypofunction and other disorders of pituitary gland
0.718 0.282 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.718 0.282 0.000
I08.0 Disorders of both mitral and aortic valves
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.716 0.284 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.716 0.284 0.000
Z63 Other problems related to primary support group, including family circumstances
0.715 0.285 0.000
E89.2 Postprocedural hypoparathyroidism
0.715 0.285 0.000
Z73.3 Stress, not elsewhere classified
0.714 0.286 0.000
J41 Simple and mucopurulent chronic bronchitis
0.714 0.286 0.000
S42.7 Multiple fractures of clavicle, scapula and humerus
0.713 0.287 0.000
M13 Other arthritis
0.713 0.287 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.713 0.287 0.000
M49 Spondylopathies in diseases classified elsewhere
0.712 0.288 0.000
S61.7 Multiple open wounds of wrist and hand
0.711 0.289 0.000
I51.8 Other ill-defined heart diseases
0.710 0.290 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.710 0.290 0.000
I05 Rheumatic mitral valve diseases
0.710 0.290 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.710 0.290 0.000
C81 Hodgkin's disease
0.710 0.290 0.000
E78.8 Other disorders of lipoprotein metabolism
0.709 0.290 0.000
D50.9 Iron deficiency anaemia, unspecified
0.709 0.291 0.000
M54.8 Other dorsalgia
0.709 0.291 0.000
M54.0 Panniculitis affecting regions of neck and back
0.709 0.291 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.709 0.291 0.000
M89.0 Algoneurodystrophy
0.707 0.293 0.000
I52 Other heart disorders in diseases classified elsewhere
0.706 0.293 0.000
I48 Atrial fibrillation and flutter
0.706 0.293 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.706 0.293 0.000
I41 Myocarditis in diseases classified elsewhere
0.706 0.293 0.000
I40 Acute myocarditis
0.706 0.293 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.706 0.293 0.000
I36 Nonrheumatic tricuspid valve disorders
0.706 0.293 0.000
I32 Pericarditis in diseases classified elsewhere
0.706 0.293 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.705 0.295 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.705 0.295 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.705 0.295 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.705 0.295 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.705 0.295 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.705 0.295 0.000
I38 Endocarditis, valve unspecified
0.704 0.296 0.000
I34 Nonrheumatic mitral valve disorders
0.704 0.296 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.703 0.296 0.000
E85 Amyloidosis
0.703 0.297 0.000
E84 Cystic fibrosis
0.703 0.297 0.000
E79 Disorders of purine and pyrimidine metabolism
0.703 0.297 0.000
E77 Disorders of glycoprotein metabolism
0.703 0.297 0.000
E76 Disorders of glycosaminoglycan metabolism
0.703 0.297 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.703 0.297 0.000
E74 Other disorders of carbohydrate metabolism
0.703 0.297 0.000
E72 Other disorders of amino-acid metabolism
0.703 0.297 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.703 0.297 0.000
E70 Disorders of aromatic amino-acid metabolism
0.703 0.297 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.703 0.297 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.703 0.297 0.000
I24 Other acute ischaemic heart diseases
0.703 0.297 0.000
I73.9 Peripheral vascular disease, unspecified
0.702 0.298 0.000
J98.8 Other specified respiratory disorders
0.701 0.298 0.000
J96 Respiratory failure, not elsewhere classified
0.701 0.299 0.000
G60 Hereditary and idiopathic neuropathy
0.700 0.300 0.000
E04 Other non-toxic goitre
0.699 0.301 0.000
S65 Injury of blood vessels at wrist and hand level
0.698 0.302 0.000
I21 Acute myocardial infarction
0.698 0.302 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.697 0.302 0.000
I72 Other aneurysm
0.697 0.303 0.000
S29 Other and unspecified injuries of thorax
0.697 0.303 0.000
M00-M03 Infectious arthropathies
0.695 0.305 0.000
I95.8 Other hypotension
0.694 0.306 0.000
I95.0 Idiopathic hypotension
0.694 0.306 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.694 0.306 0.000
F70-F79 Mental retardation
0.694 0.306 0.000
S48 Traumatic amputation of shoulder and upper arm
0.694 0.306 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.694 0.306 0.000
S44 Injury of nerves at shoulder and upper arm level
0.694 0.306 0.000
S41 Open wound of shoulder and upper arm
0.694 0.306 0.000
S47 Crushing injury of shoulder and upper arm
0.694 0.306 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.694 0.306 0.000
C64-C68 Malignant neoplasms of urinary tract
0.694 0.306 0.000
S69 Other and unspecified injuries of wrist and hand
0.692 0.308 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.692 0.308 0.000
T90 Sequelae of injuries of head
0.692 0.308 0.000
M71 Other bursopathies
0.690 0.310 0.000
D52 Folate deficiency anaemia
0.689 0.311 0.000
S00.3 Superficial injury of nose
0.689 0.311 0.000
M79.8 Other specified soft tissue disorders
0.689 0.311 0.000
S22.2 Fracture of sternum
0.689 0.311 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.689 0.311 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.689 0.311 0.000
M53 Other dorsopathies, not elsewhere classified
0.687 0.312 0.000
M85 Other disorders of bone density and structure
0.686 0.313 0.000
F80-F89 Disorders of psychological development
0.686 0.314 0.000
S60 Superficial injury of wrist and hand
0.685 0.315 0.000
E27.1 Primary adrenocortical insufficiency
0.683 0.317 0.000
D55-D59 Haemolytic anaemias
0.682 0.317 0.000
I50.0 Congestive heart failure
0.680 0.320 0.000
I45.5 Other specified heart block
0.680 0.320 0.000
I45.4 Nonspecific intraventricular block
0.680 0.320 0.000
I45.3 Trifascicular block
0.680 0.320 0.000
I45.0 Right fascicular block
0.680 0.320 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.679 0.321 0.000
I45.1 Other and unspecified right bundle-branch block
0.679 0.321 0.000
J98.9 Respiratory disorder, unspecified
0.678 0.322 0.000
T17 Foreign body in respiratory tract
0.677 0.322 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.676 0.323 0.000
E34 Other endocrine disorders
0.676 0.323 0.000
E32 Diseases of thymus
0.676 0.323 0.000
E31 Polyglandular dysfunction
0.676 0.323 0.000
E30 Disorders of puberty, not elsewhere classified
0.676 0.323 0.000
E26 Hyperaldosteronism
0.676 0.323 0.000
E25 Adrenogenital disorders
0.676 0.323 0.000
E24 Cushing's syndrome
0.676 0.323 0.000
E20 Hypoparathyroidism
0.676 0.323 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.676 0.324 0.000
G30-G32 Other degenerative diseases of the nervous system
0.676 0.324 0.000
J98.6 Disorders of diaphragm
0.676 0.324 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.676 0.324 0.000
J98.3 Compensatory emphysema
0.676 0.324 0.000
J98.2 Interstitial emphysema
0.676 0.324 0.000
E10.3 With ophthalmic complications
0.676 0.324 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.675 0.325 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.675 0.325 0.000
E89.8 Other postprocedural endocrine and metabolic disorders
0.675 0.325 0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.675 0.325 0.000
E89.5 Postprocedural testicular hypofunction
0.675 0.325 0.000
E89.4 Postprocedural ovarian failure
0.675 0.325 0.000
E89.3 Postprocedural hypopituitarism
0.675 0.325 0.000
E89.1 Postprocedural hypoinsulinaemia
0.675 0.325 0.000
G61 Inflammatory polyneuropathy
0.675 0.325 0.000
J92 Pleural plaque
0.674 0.326 0.000
Z76 Persons encountering health services in other circumstances
0.673 0.327 0.000
I21.9 Acute myocardial infarction, unspecified
0.673 0.327 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.673 0.327 0.000
S02 Fracture of skull and facial bones
0.672 0.327 0.000
S00.0 Superficial injury of scalp
0.672 0.328 0.000
I31.9 Disease of pericardium, unspecified
0.672 0.328 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.672 0.328 0.000
S90-S99 Injuries to the ankle and foot
0.671 0.328 0.000
S22.0 Fracture of thoracic vertebra
0.671 0.329 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.670 0.330 0.000
S26 Injury of heart
0.670 0.330 0.000
S25 Injury of blood vessels of thorax
0.670 0.330 0.000
S24 Injury of nerves and spinal cord at thorax level
0.670 0.330 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.670 0.330 0.000
S21 Open wound of thorax
0.670 0.330 0.000
D51 Vitamin B12 deficiency anaemia
0.670 0.330 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.670 0.330 0.000
G64 Other disorders of peripheral nervous system
0.669 0.330 0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)
0.669 0.331 0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)
0.669 0.331 0.000
M47.94 Spondylosis, unspecified (Thoracic region)
0.669 0.331 0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)
0.669 0.331 0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)
0.669 0.331 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.669 0.331 0.000
Z57 Occupational exposure to risk-factors
0.669 0.331 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.669 0.331 0.000
Q50-Q56 Congenital malformations of genital organs
0.669 0.331 0.000
S80 Superficial injury of lower leg
0.669 0.331 0.000
T66-T78 Other and unspecified effects of external causes
0.668 0.332 0.000
D80-D89 Certain disorders involving the immune mechanism
0.668 0.332 0.000
I70 Atherosclerosis
0.668 0.332 0.000
Q80-Q89 Other congenital malformations
0.668 0.332 0.000
M51.9 Intervertebral disk disorder, unspecified
0.668 0.332 0.000
S08 Traumatic amputation of part of head
0.666 0.333 0.000
S07 Crushing injury of head
0.666 0.333 0.000
S04 Injury of cranial nerves
0.666 0.333 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.666 0.333 0.000
I30 Acute pericarditis
0.666 0.334 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.666 0.334 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.665 0.335 0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level
0.665 0.335 0.000
S00.8 Superficial injury of other parts of head
0.664 0.336 0.000
S64.0 Injury of ulnar nerve at wrist and hand level
0.664 0.336 0.000
I50.1 Left ventricular failure
0.664 0.336 0.000
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)
0.663 0.336 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.663 0.337 0.000
M60 Myositis
0.663 0.337 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.663 0.337 0.000
I09 Other rheumatic heart diseases
0.662 0.338 0.000
I06 Rheumatic aortic valve diseases
0.662 0.338 0.000
I46.9 Cardiac arrest, unspecified
0.662 0.338 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.661 0.338 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.661 0.338 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.661 0.338 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.661 0.338 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.661 0.338 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.661 0.338 0.000
F11 Mental and behavioural disorders due to use of opioids
0.661 0.338 0.000
M82 Osteoporosis in diseases classified elsewhere
0.661 0.338 0.000
Z22 Carrier of infectious disease
0.661 0.339 0.000
G70-G73 Diseases of myoneural junction and muscle
0.661 0.339 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.660 0.340 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.660 0.340 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.660 0.340 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.659 0.341 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.659 0.341 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.659 0.341 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.659 0.341 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.659 0.341 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.659 0.341 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.659 0.341 0.000
T36 Poisoning by systemic antibiotics
0.659 0.341 0.000
C85.1 B-cell lymphoma, unspecified
0.658 0.342 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.657 0.342 0.000
D53 Other nutritional anaemias
0.656 0.343 0.000
S27.0 Traumatic pneumothorax
0.656 0.344 0.000
I51.5 Myocardial degeneration
0.656 0.344 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.656 0.344 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.656 0.344 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.656 0.344 0.000
I51.0 Cardiac septal defect, acquired
0.656 0.344 0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)
0.656 0.344 0.000
S46.0 Injury of tendon of the rotator cuff of shoulder
0.655 0.345 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.655 0.345 0.000
G40.8 Other epilepsy
0.654 0.346 0.000
M62 Other disorders of muscle
0.654 0.346 0.000
G62.2 Polyneuropathy due to other toxic agents
0.653 0.346 0.000
G62.1 Alcoholic polyneuropathy
0.653 0.346 0.000
G62.0 Drug-induced polyneuropathy
0.653 0.346 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.653 0.347 0.000
M54.2 Cervicalgia
0.653 0.347 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.653 0.347 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.652 0.348 0.000
J00-J06 Acute upper respiratory infections
0.651 0.349 0.000
I50.9 Heart failure, unspecified
0.651 0.349 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.650 0.350 0.000
E78.0 Pure hypercholesterolaemia
0.650 0.350 0.000
F10.2 Dependence syndrome
0.650 0.350 0.000
J20-J22 Other acute lower respiratory infections
0.650 0.350 0.000
S22.3 Fracture of rib
0.649 0.351 0.000
F17.1 Harmful use
0.648 0.352 0.000
M54.64 Pain in thoracic spine (Thoracic region)
0.648 0.352 0.000
F12.2 Dependence syndrome
0.648 0.352 0.000
M46 Other inflammatory spondylopathies
0.647 0.353 0.000
Z74.8 Other problems related to care-provider dependency
0.647 0.353 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.647 0.353 0.000
I46.0 Cardiac arrest with successful resuscitation
0.645 0.355 0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.645 0.355 0.000
Z63.4 Disappearance and death of family member
0.645 0.355 0.000
M76 Enthesopathies of lower limb, excluding foot
0.644 0.356 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.644 0.356 0.000
E50-E64 Other nutritional deficiencies
0.643 0.357 0.000
Q00-Q07 Congenital malformations of the nervous system
0.643 0.357 0.000
E78.2 Mixed hyperlipidaemia
0.642 0.358 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.642 0.358 0.000
E78.1 Pure hyperglyceridaemia
0.642 0.358 0.000
S61.1 Open wound of finger(s) with damage to nail
0.641 0.359 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.640 0.360 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.639 0.361 0.000
M54.50 Low back pain (Multiple sites in spine)
0.639 0.361 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.638 0.361 0.000
S68 Traumatic amputation of wrist and hand
0.638 0.362 0.000
E22 Hyperfunction of pituitary gland
0.638 0.362 0.000
M54.56 Low back pain (Lumbar region)
0.638 0.362 0.000
G44 Other headache syndromes
0.637 0.363 0.000
M77.4 Metatarsalgia
0.637 0.363 0.000
M81 Osteoporosis without pathological fracture
0.637 0.363 0.000
S00.5 Superficial injury of lip and oral cavity
0.637 0.363 0.000
S00.4 Superficial injury of ear
0.637 0.363 0.000
J80 Adult respiratory distress syndrome
0.636 0.364 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.635 0.365 0.000
Y40 Systemic antibiotics
0.635 0.365 0.000
D50.1 Sideropenic dysphagia
0.634 0.366 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.634 0.366 0.000
M80 Osteoporosis with pathological fracture
0.634 0.366 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.633 0.367 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.633 0.367 0.000
Q35-Q37 Cleft lip and cleft palate
0.633 0.367 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.633 0.367 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.633 0.367 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.633 0.367 0.000
M47.84 Other spondylosis (Thoracic region)
0.633 0.367 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.633 0.367 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.633 0.367 0.000
S42.9 Fracture of shoulder girdle, part unspecified
0.632 0.368 0.000
S42.8 Fracture of other parts of shoulder and upper arm
0.632 0.368 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.631 0.369 0.000
Z74.2 Need for assistance at home and no other household member able to render care
0.631 0.369 0.000
S64.9 Injury of unspecified nerve at wrist and hand level
0.631 0.369 0.000
S64.8 Injury of other nerves at wrist and hand level
0.631 0.369 0.000
S64.7 Injury of multiple nerves at wrist and hand level
0.631 0.369 0.000
S64.2 Injury of radial nerve at wrist and hand level
0.631 0.369 0.000
S64.1 Injury of median nerve at wrist and hand level
0.631 0.369 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.630 0.370 0.000
D00-D09 In situ neoplasms
0.630 0.370 0.000
G20-G26 Extrapyramidal and movement disorders
0.629 0.370 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.629 0.371 0.000
M47.89 Other spondylosis (Site unspecified)
0.629 0.371 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.629 0.371 0.000
S42.2 Fracture of upper end of humerus
0.628 0.372 0.000
C50-C50 Malignant neoplasm of breast
0.628 0.372 0.000
M51.3 Other specified intervertebral disk degeneration
0.628 0.372 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.628 0.372 0.000
M51.4 Schmorl's nodes
0.628 0.372 0.000
F60 Specific personality disorders
0.628 0.372 0.000
I51.9 Heart disease, unspecified
0.627 0.373 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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