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Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs76984655
log Bayes Factor = 7.79218
Chromosome 14   position 51,045,350  (GRCh37) Explore rs76984655 on Ensembl!
Variant rs76984655 is part of Cluster X0052

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
0.999 0.001 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.998 0.002 0.000
Chapter VI Diseases of the nervous system
0.996 0.004 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.993 0.007 0.000
M50-M54 Other dorsopathies
0.992 0.008 0.000
H30-H36 Disorders of choroid and retina
0.991 0.009 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.990 0.010 0.000
H35 Other retinal disorders
0.983 0.017 0.000
M54 Dorsalgia
0.980 0.020 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.980 0.020 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.977 0.023 0.000
Chapter IX Diseases of the circulatory system
0.976 0.024 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.975 0.025 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.967 0.033 0.000
G90-G99 Other disorders of the nervous system
0.965 0.035 0.000
O36 Maternal care for other known or suspected foetal problems
0.962 0.038 0.000
H35.8 Other specified retinal disorders
0.960 0.040 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.956 0.044 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.951 0.049 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.948 0.052 0.000
M50 Cervical disk disorders
0.946 0.054 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.942 0.058 0.000
S10-S19 Injuries to the neck
0.941 0.059 0.000
O36.8 Maternal care for other specified foetal problems
0.940 0.060 0.000
E20-E35 Disorders of other endocrine glands
0.939 0.061 0.000
H25-H28 Disorders of lens
0.935 0.065 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.932 0.068 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.926 0.074 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.923 0.077 0.000
I77 Other disorders of arteries and arterioles
0.917 0.083 0.000
I35 Nonrheumatic aortic valve disorders
0.916 0.084 0.000
I30-I52 Other forms of heart disease
0.916 0.084 0.000
M50.0 Cervical disk disorder with myelopathy
0.915 0.085 0.000
M54.3 Sciatica
0.915 0.085 0.000
O47 False labour
0.908 0.092 0.000
I35.0 Aortic (valve) stenosis
0.907 0.093 0.000
L82 Seborrhoeic keratosis
0.906 0.094 0.000
M86-M90 Other osteopathies
0.906 0.094 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.905 0.095 0.000
I60-I69 Cerebrovascular diseases
0.905 0.095 0.000
I77.1 Stricture of artery
0.905 0.095 0.000
I05-I09 Chronic rheumatic heart diseases
0.901 0.099 0.000
L89 Decubitus ulcer
0.900 0.100 0.000
Q60-Q64 Congenital malformations of the urinary system
0.898 0.102 0.000
M65-M68 Disorders of synovium and tendon
0.891 0.109 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.890 0.110 0.000
M54.9 Dorsalgia, unspecified
0.885 0.115 0.000
H34 Retinal vascular occlusions
0.884 0.116 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.879 0.121 0.000
I67 Other cerebrovascular diseases
0.875 0.125 0.000
I70 Atherosclerosis
0.870 0.130 0.000
L20-L30 Dermatitis and eczema
0.870 0.130 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.870 0.130 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.865 0.135 0.000
I51 Complications and ill-defined descriptions of heart disease
0.864 0.136 0.000
D80-D89 Certain disorders involving the immune mechanism
0.864 0.136 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.863 0.137 0.000
H26 Other cataract
0.859 0.141 0.000
G30-G32 Other degenerative diseases of the nervous system
0.856 0.144 0.000
T90 Sequelae of injuries of head
0.856 0.144 0.000
L85 Other epidermal thickening
0.854 0.146 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.849 0.151 0.000
Q61 Cystic kidney disease
0.847 0.153 0.000
G95 Other diseases of spinal cord
0.845 0.155 0.000
H53-H54 Visual disturbances and blindness
0.844 0.156 0.000
H26.8 Other specified cataract
0.843 0.157 0.000
I67.8 Other specified cerebrovascular diseases
0.841 0.159 0.000
I35.1 Aortic (valve) insufficiency
0.839 0.161 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.838 0.162 0.000
H10-H13 Disorders of conjunctiva
0.837 0.163 0.000
G56 Mononeuropathies of upper limb
0.836 0.164 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.833 0.167 0.000
M54.5 Low back pain
0.831 0.169 0.000
M15-M19 Arthrosis
0.830 0.170 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.830 0.170 0.000
G96 Other disorders of central nervous system
0.829 0.171 0.000
Chapter XX External causes of morbidity and mortality
0.829 0.171 0.000
O36.0 Maternal care for rhesus isoimmunisation
0.828 0.172 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.827 0.173 0.000
E10-E14 Diabetes mellitus
0.827 0.173 0.000
I07 Rheumatic tricuspid valve diseases
0.827 0.173 0.000
E70-E90 Metabolic disorders
0.825 0.175 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.825 0.175 0.000
O60-O75 Complications of labour and delivery
0.825 0.175 0.000
G70-G73 Diseases of myoneural junction and muscle
0.824 0.176 0.000
M60-M63 Disorders of muscles
0.822 0.178 0.000
T93 Sequelae of injuries of lower limb
0.822 0.178 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.821 0.179 0.000
M54.36 Sciatica (Lumbar region)
0.821 0.179 0.000
I47 Paroxysmal tachycardia
0.821 0.179 0.000
S40-S49 Injuries to the shoulder and upper arm
0.819 0.181 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.818 0.182 0.000
M65 Synovitis and tenosynovitis
0.816 0.184 0.000
S32 Fracture of lumbar spine and pelvis
0.816 0.184 0.000
E27 Other disorders of adrenal gland
0.815 0.185 0.000
H35.2 Other proliferative retinopathy
0.814 0.186 0.000
L88 Pyoderma gangrenosum
0.814 0.186 0.000
H34.8 Other retinal vascular occlusions
0.813 0.187 0.000
S14 Injury of nerves and spinal cord at neck level
0.812 0.188 0.000
M91-M94 Chondropathies
0.812 0.188 0.000
H35.3 Degeneration of macula and posterior pole
0.811 0.189 0.000
Q50-Q56 Congenital malformations of genital organs
0.809 0.191 0.000
S12 Fracture of neck
0.809 0.191 0.000
H25 Senile cataract
0.807 0.193 0.000
S20-S29 Injuries to the thorax
0.805 0.195 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.804 0.196 0.000
L29 Pruritus
0.802 0.198 0.000
M89 Other disorders of bone
0.802 0.198 0.000
H40-H42 Glaucoma
0.799 0.201 0.000
M54.1 Radiculopathy
0.796 0.204 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.796 0.204 0.000
M50.3 Other cervical disk degeneration
0.796 0.204 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.795 0.205 0.000
D86 Sarcoidosis
0.792 0.208 0.000
E86 Volume depletion
0.791 0.209 0.000
I51.7 Cardiomegaly
0.790 0.210 0.000
E40-E46 Malnutrition
0.789 0.211 0.000
H35.0 Background retinopathy and retinal vascular changes
0.789 0.211 0.000
I74 Arterial embolism and thrombosis
0.788 0.212 0.000
L50-L54 Urticaria and erythema
0.788 0.212 0.000
L81 Other disorders of pigmentation
0.787 0.213 0.000
M54.6 Pain in thoracic spine
0.786 0.213 0.000
O85-O92 Complications predominantly related to the puerperium
0.786 0.214 0.000
L89.2 Stage III decubitus ulcer
0.784 0.216 0.000
L83 Acanthosis nigricans
0.784 0.216 0.000
T91 Sequelae of injuries of neck and trunk
0.780 0.220 0.000
I35.8 Other aortic valve disorders
0.780 0.220 0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium
0.778 0.221 0.000
O42 Premature rupture of membranes
0.775 0.225 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.775 0.225 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.775 0.225 0.000
E50-E64 Other nutritional deficiencies
0.774 0.226 0.000
I07.1 Tricuspid insufficiency
0.774 0.226 0.000
H54 Blindness and low vision
0.773 0.226 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.770 0.230 0.000
L85.9 Epidermal thickening, unspecified
0.768 0.232 0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
0.768 0.232 0.000
S19 Other and unspecified injuries of neck
0.764 0.236 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.764 0.236 0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
0.763 0.237 0.000
E29 Testicular dysfunction
0.761 0.239 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.760 0.240 0.000
Q61.3 Polycystic kidney, unspecified
0.759 0.241 0.000
L89.3 Stage IV decubitus ulcer
0.758 0.242 0.000
D55-D59 Haemolytic anaemias
0.756 0.243 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.756 0.244 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.750 0.250 0.000
H11 Other disorders of conjunctiva
0.750 0.250 0.000
O72 Postpartum haemorrhage
0.749 0.251 0.000
O80-O84 Delivery
0.749 0.251 0.000
G97.0 Cerebrospinal fluid leak from spinal puncture
0.749 0.251 0.000
D86.9 Sarcoidosis, unspecified
0.749 0.251 0.000
M54.39 Sciatica (Site unspecified)
0.749 0.251 0.000
T39.1 4-Aminophenol derivatives
0.747 0.253 0.000
I08 Multiple valve diseases
0.746 0.254 0.000
M45-M49 Spondylopathies
0.746 0.254 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.745 0.255 0.000
I70.0 Atherosclerosis of aorta
0.744 0.256 0.000
H25.8 Other senile cataract
0.744 0.256 0.000
I60 Subarachnoid haemorrhage
0.743 0.257 0.000
O30 Multiple gestation
0.743 0.257 0.000
H35.6 Retinal haemorrhage
0.742 0.258 0.000
O36.4 Maternal care for intra-uterine death
0.741 0.259 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.741 0.259 0.000
G50 Disorders of trigeminal nerve
0.739 0.261 0.000
E23 Hypofunction and other disorders of pituitary gland
0.739 0.261 0.000
L89.0 Stage I decubitus ulcer and pressure area
0.737 0.263 0.000
M18 Arthrosis of first carpometacarpal joint
0.735 0.265 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.734 0.266 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.734 0.266 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.732 0.268 0.000
E34 Other endocrine disorders
0.731 0.269 0.000
L27 Dermatitis due to substances taken internally
0.731 0.269 0.000
M90 Osteopathies in diseases classified elsewhere
0.731 0.269 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.731 0.269 0.000
H35.7 Separation of retinal layers
0.729 0.271 0.000
G97.8 Other postprocedural disorders of nervous system
0.728 0.272 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.727 0.273 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.725 0.275 0.000
E28 Ovarian dysfunction
0.725 0.275 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.724 0.276 0.000
G56.2 Lesion of ulnar nerve
0.723 0.277 0.000
G56.1 Other lesions of median nerve
0.723 0.277 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.723 0.277 0.000
E24 Cushing's syndrome
0.722 0.278 0.000
M65.3 Trigger finger
0.722 0.278 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.722 0.278 0.000
M54.56 Low back pain (Lumbar region)
0.721 0.279 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.721 0.279 0.000
T90.2 Sequelae of fracture of skull and facial bones
0.721 0.279 0.000
O43 Placental disorders
0.720 0.280 0.000
S14.1 Other and unspecified injuries of cervical spinal cord
0.720 0.280 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.720 0.280 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.717 0.283 0.000
H21 Other disorders of iris and ciliary body
0.717 0.283 0.000
E11 Non-insulin-dependent diabetes mellitus
0.717 0.283 0.000
O47.0 False labour before 37 completed weeks of gestation
0.716 0.284 0.000
S70-S79 Injuries to the hip and thigh
0.716 0.284 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.715 0.285 0.000
H20 Iridocyclitis
0.714 0.286 0.000
L94 Other localised connective tissue disorders
0.714 0.286 0.000
H43-H45 Disorders of vitreous body and globe
0.714 0.286 0.000
Q00-Q07 Congenital malformations of the nervous system
0.714 0.286 0.000
M54.37 Sciatica (Lumbosacral region)
0.713 0.286 0.000
T66-T78 Other and unspecified effects of external causes
0.713 0.287 0.000
S10 Superficial injury of neck
0.712 0.288 0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
0.712 0.288 0.000
O45 Premature separation of placenta [abruptio placentae]
0.712 0.288 0.000
O33 Maternal care for known or suspected disproportion
0.712 0.288 0.000
O31 Complications specific to multiple gestation
0.712 0.288 0.000
O40 Polyhydramnios
0.712 0.288 0.000
M89.8 Other specified disorders of bone
0.712 0.288 0.000
H35.4 Peripheral retinal degeneration
0.712 0.288 0.000
O21 Excessive vomiting in pregnancy
0.711 0.289 0.000
G95.2 Cord compression, unspecified
0.711 0.289 0.000
I67.9 Cerebrovascular disease, unspecified
0.710 0.290 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.710 0.290 0.000
H31 Other disorders of choroid
0.710 0.290 0.000
H30 Chorioretinal inflammation
0.710 0.290 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.710 0.290 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.710 0.290 0.000
T33-T35 Frostbite
0.709 0.290 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.709 0.290 0.000
T00-T07 Injuries involving multiple body regions
0.709 0.290 0.000
Q61.2 Polycystic kidney, adult type
0.709 0.291 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.708 0.292 0.000
M40-M43 Deforming dorsopathies
0.708 0.292 0.000
H25.1 Senile nuclear cataract
0.708 0.292 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.707 0.293 0.000
G54 Nerve root and plexus disorders
0.707 0.293 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.707 0.293 0.000
E10 Insulin-dependent diabetes mellitus
0.705 0.295 0.000
H35.1 Retinopathy of prematurity
0.705 0.295 0.000
M88 Paget's disease of bone [osteitis deformans]
0.704 0.296 0.000
O34.7 Maternal care for abnormality of vulva and perineum
0.703 0.297 0.000
M54.8 Other dorsalgia
0.703 0.297 0.000
M54.0 Panniculitis affecting regions of neck and back
0.703 0.297 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.702 0.298 0.000
S32.5 Fracture of pubis
0.702 0.298 0.000
M00-M03 Infectious arthropathies
0.702 0.298 0.000
L10-L14 Bullous disorders
0.700 0.300 0.000
I00-I02 Acute rheumatic fever
0.699 0.300 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.699 0.301 0.000
Q35-Q37 Cleft lip and cleft palate
0.699 0.301 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.699 0.301 0.000
E22 Hyperfunction of pituitary gland
0.699 0.301 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.699 0.301 0.000
O23 Infections of genito-urinary tract in pregnancy
0.698 0.302 0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.698 0.302 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.697 0.303 0.000
S60-S69 Injuries to the wrist and hand
0.697 0.303 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.697 0.303 0.000
T92 Sequelae of injuries of upper limb
0.697 0.303 0.000
Q76 Congenital malformations of spine and bony thorax
0.696 0.304 0.000
M62 Other disorders of muscle
0.696 0.304 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.695 0.305 0.000
G91 Hydrocephalus
0.695 0.305 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.695 0.305 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.695 0.305 0.000
L29.0 Pruritus ani
0.694 0.306 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.694 0.306 0.000
L87 Transepidermal elimination disorders
0.694 0.306 0.000
L86 Keratoderma in diseases classified elsewhere
0.694 0.306 0.000
L80 Vitiligo
0.694 0.306 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.694 0.306 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.693 0.307 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.692 0.308 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.692 0.308 0.000
G92 Toxic encephalopathy
0.692 0.308 0.000
T90.8 Sequelae of other specified injuries of head
0.691 0.309 0.000
G71 Primary disorders of muscles
0.691 0.309 0.000
T90.5 Sequelae of intracranial injury
0.691 0.309 0.000
Q80-Q89 Other congenital malformations
0.690 0.310 0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy
0.690 0.310 0.000
O36.3 Maternal care for signs of foetal hypoxia
0.690 0.310 0.000
O36.2 Maternal care for hydrops foetalis
0.690 0.310 0.000
O36.1 Maternal care for other isoimmunisation
0.690 0.310 0.000
G58 Other mononeuropathies
0.690 0.310 0.000
G96.1 Disorders of meninges, not elsewhere classified
0.689 0.311 0.000
E26 Hyperaldosteronism
0.689 0.311 0.000
D80 Immunodeficiency with predominantly antibody defects
0.687 0.313 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.686 0.314 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.685 0.314 0.000
O97 Death from sequelae of direct obstetric causes
0.685 0.314 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.685 0.314 0.000
O95 Obstetric death of unspecified cause
0.685 0.314 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.685 0.314 0.000
H35.5 Hereditary retinal dystrophy
0.685 0.315 0.000
G59.0 Diabetic mononeuropathy
0.685 0.315 0.000
M54.4 Lumbago with sciatica
0.683 0.316 0.000
H54.4 Blindness, one eye
0.683 0.317 0.000
E83 Disorders of mineral metabolism
0.683 0.317 0.000
T98 Sequelae of other and unspecified effects of external causes
0.682 0.318 0.000
T95 Sequelae of burns, corrosions and frostbite
0.682 0.318 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.682 0.318 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.682 0.318 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.682 0.318 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.682 0.318 0.000
V40-V49 Car occupant injured in transport accident
0.682 0.318 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.681 0.319 0.000
G52 Disorders of other cranial nerves
0.680 0.320 0.000
G30 Alzheimer's disease
0.680 0.320 0.000
I50 Heart failure
0.679 0.321 0.000
M50.9 Cervical disk disorder, unspecified
0.678 0.321 0.000
M50.8 Other cervical disk disorders
0.678 0.321 0.000
I67.1 Cerebral aneurysm, nonruptured
0.678 0.322 0.000
M66 Spontaneous rupture of synovium and tendon
0.678 0.322 0.000
E53 Deficiency of other B group vitamins
0.677 0.323 0.000
G90 Disorders of autonomic nervous system
0.677 0.323 0.000
S42 Fracture of shoulder and upper arm
0.677 0.323 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.675 0.325 0.000
I47.2 Ventricular tachycardia
0.675 0.325 0.000
S17 Crushing injury of neck
0.675 0.325 0.000
S15 Injury of blood vessels at neck level
0.675 0.325 0.000
S11 Open wound of neck
0.675 0.325 0.000
S18 Traumatic amputation at neck level
0.675 0.325 0.000
S16 Injury of muscle and tendon at neck level
0.675 0.325 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.673 0.326 0.000
E32 Diseases of thymus
0.673 0.326 0.000
E31 Polyglandular dysfunction
0.673 0.326 0.000
E30 Disorders of puberty, not elsewhere classified
0.673 0.326 0.000
E25 Adrenogenital disorders
0.673 0.326 0.000
E20 Hypoparathyroidism
0.673 0.326 0.000
L29.9 Pruritus, unspecified
0.673 0.327 0.000
S27 Injury of other and unspecified intrathoracic organs
0.673 0.327 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.672 0.328 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.671 0.329 0.000
H17 Corneal scars and opacities
0.671 0.329 0.000
G51 Facial nerve disorders
0.671 0.329 0.000
M54.16 Radiculopathy (Lumbar region)
0.671 0.329 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.670 0.329 0.000
O36.5 Maternal care for poor foetal growth
0.670 0.330 0.000
Y45.2 Propionic acid derivatives
0.669 0.331 0.000
O47.9 False labour, unspecified
0.669 0.331 0.000
Q61.0 Congenital single renal cyst
0.669 0.331 0.000
M16 Coxarthrosis [arthrosis of hip]
0.669 0.331 0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified
0.668 0.332 0.000
O34.8 Maternal care for other abnormalities of pelvic organs
0.668 0.332 0.000
O34.6 Maternal care for abnormality of vagina
0.668 0.332 0.000
O34.5 Maternal care for other abnormalities of gravid uterus
0.668 0.332 0.000
O34.4 Maternal care for other abnormalities of cervix
0.668 0.332 0.000
O34.3 Maternal care for cervical incompetence
0.668 0.332 0.000
O34.0 Maternal care for congenital malformation of uterus
0.668 0.332 0.000
T23 Burn and corrosion of wrist and hand
0.668 0.332 0.000
I51.0 Cardiac septal defect, acquired
0.668 0.332 0.000
I36 Nonrheumatic tricuspid valve disorders
0.668 0.332 0.000
H35.9 Retinal disorder, unspecified
0.667 0.333 0.000
I51.9 Heart disease, unspecified
0.666 0.334 0.000
S32.1 Fracture of sacrum
0.666 0.334 0.000
S32.3 Fracture of ilium
0.666 0.334 0.000
I47.1 Supraventricular tachycardia
0.666 0.334 0.000
G95.0 Syringomyelia and syringobulbia
0.665 0.334 0.000
G96.0 Cerebrospinal fluid leak
0.665 0.335 0.000
D68 Other coagulation defects
0.665 0.335 0.000
O72.1 Other immediate postpartum haemorrhage
0.664 0.336 0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium
0.664 0.336 0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
0.664 0.336 0.000
I31 Other diseases of pericardium
0.663 0.337 0.000
D50-D53 Nutritional anaemias
0.663 0.337 0.000
E11.4 With neurological complications
0.662 0.338 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.662 0.338 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.661 0.339 0.000
S32.0 Fracture of lumbar vertebra
0.660 0.340 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.659 0.341 0.000
H54.7 Unspecified visual loss
0.659 0.341 0.000
L52 Erythema nodosum
0.658 0.341 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.657 0.342 0.000
I77.5 Necrosis of artery
0.657 0.343 0.000
I77.4 Coeliac artery compression syndrome
0.657 0.343 0.000
I77.3 Arterial fibromuscular dysplasia
0.657 0.343 0.000
I77.2 Rupture of artery
0.657 0.343 0.000
I77.0 Arteriovenous fistula, acquired
0.657 0.343 0.000
M80-M85 Disorders of bone density and structure
0.657 0.343 0.000
I52 Other heart disorders in diseases classified elsewhere
0.657 0.343 0.000
I48 Atrial fibrillation and flutter
0.657 0.343 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.657 0.343 0.000
I41 Myocarditis in diseases classified elsewhere
0.657 0.343 0.000
I40 Acute myocarditis
0.657 0.343 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.657 0.343 0.000
I37 Pulmonary valve disorders
0.657 0.343 0.000
I32 Pericarditis in diseases classified elsewhere
0.657 0.343 0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
0.656 0.343 0.000
L89.9 Decubitus ulcer and pressure area, unspecified
0.656 0.343 0.000
L93 Lupus erythematosus
0.656 0.344 0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue
0.656 0.344 0.000
T20 Burn and corrosion of head and neck
0.656 0.344 0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)
0.656 0.344 0.000
M54.35 Sciatica (Thoracolumbar region)
0.656 0.344 0.000
M54.34 Sciatica-Thoracic
0.656 0.344 0.000
M54.33 Sciatica-Cervicothoracic
0.656 0.344 0.000
M54.32 Sciatica-Cervical
0.656 0.344 0.000
M54.31 Sciatica-Occipit-atl-axl
0.656 0.344 0.000
M54.30 Sciatica (Multiple sites in spine)
0.656 0.344 0.000
H40 Glaucoma
0.655 0.345 0.000
O44 Placenta praevia
0.655 0.345 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.655 0.345 0.000
I51.4 Myocarditis, unspecified
0.655 0.345 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.655 0.345 0.000
T93.9 Sequelae of unspecified injury of lower limb
0.655 0.345 0.000
M65.34 Trigger finger-Hand
0.654 0.346 0.000
S12.2 Fracture of other specified cervical vertebra
0.654 0.346 0.000
G55.3 Nerve root and plexus compressions in other dorsopathies
0.654 0.346 0.000
I70.00 Atherosclerosis of aorta (without gangrene)
0.654 0.346 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.652 0.348 0.000
E46 Unspecified protein-energy malnutrition
0.652 0.348 0.000
H16 Keratitis
0.651 0.348 0.000
L81.4 Other melanin hyperpigmentation
0.651 0.349 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.650 0.350 0.000
Q55 Other congenital malformations of male genital organs
0.650 0.350 0.000
M53 Other dorsopathies, not elsewhere classified
0.649 0.350 0.000
M05-M14 Inflammatory polyarthropathies
0.649 0.351 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.649 0.351 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.649 0.351 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.649 0.351 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.649 0.351 0.000
T36 Poisoning by systemic antibiotics
0.649 0.351 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.649 0.351 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.649 0.351 0.000
G55.0 Nerve root and plexus compressions in neoplastic disease
0.649 0.351 0.000
E27.2 Addisonian crisis
0.648 0.351 0.000
M54.64 Pain in thoracic spine (Thoracic region)
0.648 0.352 0.000
V80-V89 Other land transport accidents
0.647 0.353 0.000
Q53 Undescended testicle
0.646 0.354 0.000
I09 Other rheumatic heart diseases
0.646 0.354 0.000
I06 Rheumatic aortic valve diseases
0.646 0.354 0.000
E73 Lactose intolerance
0.646 0.354 0.000
I51.8 Other ill-defined heart diseases
0.646 0.354 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.645 0.355 0.000
S12.7 Multiple fractures of cervical spine
0.644 0.356 0.000
Q64 Other congenital malformations of urinary system
0.644 0.356 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.644 0.356 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.644 0.356 0.000
M92 Other juvenile osteochondrosis
0.644 0.356 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.643 0.357 0.000
S20 Superficial injury of thorax
0.643 0.357 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.642 0.358 0.000
W50-W64 Exposure to animate mechanical forces
0.642 0.358 0.000
O26.8 Other specified pregnancy-related conditions
0.641 0.359 0.000
M50.1 Cervical disk disorder with radiculopathy
0.640 0.360 0.000
E27.1 Primary adrenocortical insufficiency
0.640 0.360 0.000
S40 Superficial injury of shoulder and upper arm
0.639 0.361 0.000
T91.1 Sequelae of fracture of spine
0.639 0.361 0.000
G63.2 Diabetic polyneuropathy
0.639 0.361 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.639 0.361 0.000
H33 Retinal detachments and breaks
0.638 0.362 0.000
M87 Osteonecrosis
0.638 0.362 0.000
S19.9 Unspecified injury of neck
0.637 0.363 0.000
D59 Acquired haemolytic anaemia
0.637 0.363 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.637 0.363 0.000
M47 Spondylosis
0.637 0.363 0.000
G95.8 Other specified diseases of spinal cord
0.636 0.363 0.000
I62 Other nontraumatic intracranial haemorrhage
0.636 0.364 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.635 0.365 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.634 0.366 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.634 0.366 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.634 0.366 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.634 0.366 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.634 0.366 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.634 0.366 0.000
T90.4 Sequelae of injury of eye and orbit
0.634 0.366 0.000
H34.9 Retinal vascular occlusion, unspecified
0.634 0.366 0.000
H34.1 Central retinal artery occlusion
0.634 0.366 0.000
H34.0 Transient retinal artery occlusion
0.634 0.366 0.000
T93.2 Sequelae of other fractures of lower limb
0.634 0.366 0.000
E29.1 Testicular hypofunction
0.634 0.366 0.000
O86 Other puerperal infections
0.633 0.367 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.633 0.367 0.000
L27.0 Generalised skin eruption due to drugs and medicaments
0.632 0.368 0.000
Y45.0 Opioids and related analgesics
0.632 0.368 0.000
G72 Other myopathies
0.631 0.369 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.630 0.370 0.000
S37 Injury of urinary and pelvic organs
0.630 0.370 0.000
S36 Injury of intra-abdominal organs
0.630 0.370 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.630 0.370 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.630 0.370 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.630 0.370 0.000
S31 Open wound of abdomen, lower back and pelvis
0.630 0.370 0.000
L92.8 Other granulomatous disorders of skin and subcutaneous tissue
0.630 0.370 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.629 0.371 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.629 0.371 0.000
G60 Hereditary and idiopathic neuropathy
0.628 0.371 0.000
X10-X19 Contact with heat and hot substances
0.628 0.372 0.000
L85.8 Other specified epidermal thickening
0.628 0.372 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.628 0.372 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.628 0.372 0.000
I67.5 Moyamoya disease
0.628 0.372 0.000
I67.4 Hypertensive encephalopathy
0.628 0.372 0.000
I67.3 Progressive vascular leukoencephalopathy
0.628 0.372 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.628 0.372 0.000
I72 Other aneurysm
0.627 0.372 0.000
E65-E68 Obesity and other hyperalimentation
0.627 0.373 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.627 0.373 0.000
Q63 Other congenital malformations of kidney
0.627 0.373 0.000
O32.2 Maternal care for transverse and oblique lie
0.626 0.374 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.625 0.375 0.000
L29.2 Pruritus vulvae
0.625 0.375 0.000
I70.9 Generalised and unspecified atherosclerosis
0.624 0.376 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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