TreeWAS – Variant ID: rs16893349

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter XV Pregnancy, childbirth and the puerperium	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
Chapter VII Diseases of the eye and adnexa	1.000	0.000
Chapter II Neoplasms	1.000	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.999	0.001
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.996	0.004
C15-C26 Malignant neoplasms of digestive organs	0.994	0.006
H30-H36 Disorders of choroid and retina	0.993	0.007
Chapter IV Endocrine, nutritional and metabolic diseases	0.992	0.008
H43-H45 Disorders of vitreous body and globe	0.991	0.009
S20-S29 Injuries to the thorax	0.984	0.016
H35 Other retinal disorders	0.984	0.016
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.983	0.017
C18 Malignant neoplasm of colon	0.983	0.017
O20-O29 Other maternal disorders predominantly related to pregnancy	0.980	0.020
O60-O75 Complications of labour and delivery	0.978	0.022
Chapter IX Diseases of the circulatory system	0.971	0.029
H43 Disorders of vitreous body	0.969	0.031
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.968	0.032
Chapter X Diseases of the respiratory system	0.966	0.034
I30-I52 Other forms of heart disease	0.963	0.037
H35.3 Degeneration of macula and posterior pole	0.962	0.038
E70-E90 Metabolic disorders	0.960	0.040
Chapter XX External causes of morbidity and mortality	0.957	0.043
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.956	0.044
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.949	0.051
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.948	0.052
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.944	0.056
H43.8 Other disorders of vitreous body	0.943	0.057
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.941	0.059
C34 Malignant neoplasm of bronchus and lung	0.938	0.062
T81 Complications of procedures, not elsewhere classified	0.937	0.063
O00-O08 Pregnancy with abortive outcome	0.935	0.065
C78.0 Secondary malignant neoplasm of lung	0.931	0.069
O20 Haemorrhage in early pregnancy	0.931	0.069
E87 Other disorders of fluid, electrolyte and acid-base balance	0.931	0.069
C64-C68 Malignant neoplasms of urinary tract	0.926	0.074
I05-I09 Chronic rheumatic heart diseases	0.921	0.079
S22 Fracture of rib(s), sternum and thoracic spine	0.918	0.082
I50 Heart failure	0.914	0.086
E87.6 Hypokalaemia	0.914	0.086
O36 Maternal care for other known or suspected foetal problems	0.911	0.089
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.911	0.089
H25-H28 Disorders of lens	0.910	0.090
H44 Disorders of globe	0.907	0.093
J90-J94 Other diseases of pleura	0.906	0.094
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.905	0.095
I35 Nonrheumatic aortic valve disorders	0.897	0.103
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.894	0.106
C18.0 Caecum	0.891	0.109
T83.0 Mechanical complication of urinary (indwelling) catheter	0.890	0.110
O63 Long labour	0.886	0.114
C67 Malignant neoplasm of bladder	0.883	0.117
I46 Cardiac arrest	0.883	0.117
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.881	0.119
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified	0.879	0.121
E86 Volume depletion	0.878	0.122
S20 Superficial injury of thorax	0.877	0.123
Chapter XXI Factors influencing health status and contact with health services	0.873	0.127
C50-C50 Malignant neoplasm of breast	0.871	0.129
Y40 Systemic antibiotics	0.866	0.134
C18.2 Ascending colon	0.866	0.134
C78.7 Secondary malignant neoplasm of liver	0.866	0.134
E10-E14 Diabetes mellitus	0.866	0.134
O03 Spontaneous abortion	0.865	0.135
S10-S19 Injuries to the neck	0.864	0.136
C34.3 Lower lobe, bronchus or lung	0.863	0.137
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.862	0.138
J90 Pleural effusion, not elsewhere classified	0.862	0.138
C77.2 Intra-abdominal lymph nodes	0.860	0.140
H10-H13 Disorders of conjunctiva	0.859	0.141
S27 Injury of other and unspecified intrathoracic organs	0.859	0.141
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.856	0.144
I08 Multiple valve diseases	0.856	0.144
O24 Diabetes mellitus in pregnancy	0.851	0.149
I42 Cardiomyopathy	0.850	0.150
Z96 Presence of other functional implants	0.849	0.151
O20.0 Threatened abortion	0.849	0.151
T85 Complications of other internal prosthetic devices, implants and grafts	0.849	0.151
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.846	0.154
Q60-Q64 Congenital malformations of the urinary system	0.844	0.156
Z96.1 Presence of intraocular lens	0.843	0.157
H35.6 Retinal haemorrhage	0.843	0.157
S22.4 Multiple fractures of ribs	0.841	0.159
T79-T79 Certain early complications of trauma	0.837	0.163
S90-S99 Injuries to the ankle and foot	0.837	0.163
T86 Failure and rejection of transplanted organs and tissues	0.836	0.164
H36 Retinal disorders in diseases classified elsewhere	0.836	0.164
E10 Insulin-dependent diabetes mellitus	0.835	0.165
Chapter VI Diseases of the nervous system	0.834	0.166
O03.4 Incomplete, without complication	0.832	0.168
I51 Complications and ill-defined descriptions of heart disease	0.830	0.170
C25 Malignant neoplasm of pancreas	0.829	0.171
C21 Malignant neoplasm of anus and anal canal	0.829	0.171
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.829	0.171
I50.1 Left ventricular failure	0.828	0.172
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.826	0.174
E40-E46 Malnutrition	0.826	0.174
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.825	0.175
E85 Amyloidosis	0.825	0.175
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.825	0.175
Z96.0 Presence of urogenital implants	0.821	0.179
C18.9 Colon, unspecified	0.821	0.179
O72 Postpartum haemorrhage	0.820	0.180
I50.0 Congestive heart failure	0.816	0.184
E10.9 Without complications	0.814	0.186
Z93 Artificial opening status	0.813	0.187
E20-E35 Disorders of other endocrine glands	0.813	0.187
O63.1 Prolonged second stage (of labour)	0.810	0.190
O36.0 Maternal care for rhesus isoimmunisation	0.809	0.191
C34.2 Middle lobe, bronchus or lung	0.806	0.194
H46-H48 Disorders of optic nerve and visual pathways	0.805	0.195
C67.2 Lateral wall of bladder	0.803	0.197
O94-O99 Other obstetric conditions, not elsewhere classified	0.802	0.198
H20 Iridocyclitis	0.802	0.198
C26 Malignant neoplasm of other and ill-defined digestive organs	0.802	0.198
H26 Other cataract	0.801	0.199
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.798	0.202
C16 Malignant neoplasm of stomach	0.796	0.204
Chapter XII Diseases of the skin and subcutaneous tissue	0.796	0.204
D37-D48 Neoplasms of uncertain or unknown behaviour	0.796	0.204
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.795	0.205
O47 False labour	0.795	0.205
J09-J18 Influenza and pneumonia	0.794	0.206
E87.7 Fluid overload	0.793	0.207
J60-J70 Lung diseases due to external agents	0.793	0.207
I46.9 Cardiac arrest, unspecified	0.791	0.209
M50-M54 Other dorsopathies	0.791	0.209
I70-I79 Diseases of arteries, arterioles and capillaries	0.791	0.209
H33 Retinal detachments and breaks	0.789	0.211
O69 Labour and delivery complicated by umbilical cord complications	0.788	0.211
C34.1 Upper lobe, bronchus or lung	0.787	0.213
S20.8 Superficial injuries of other and unspecified parts of thorax	0.785	0.215
S22.40 Multiple fractures of ribs (closed)	0.785	0.215
O70 Perineal laceration during delivery	0.784	0.216
J95-J99 Other diseases of the respiratory system	0.784	0.216
I51.8 Other ill-defined heart diseases	0.783	0.217
C18.5 Splenic flexure	0.783	0.217
C18.4 Transverse colon	0.782	0.218
O23 Infections of genito-urinary tract in pregnancy	0.782	0.218
M51 Other intervertebral disk disorders	0.779	0.221
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.778	0.222
H35.5 Hereditary retinal dystrophy	0.778	0.222
C50 Malignant neoplasm of breast	0.778	0.222
H53-H54 Visual disturbances and blindness	0.778	0.222
C77.4 Inguinal and lower limb lymph nodes	0.778	0.222
O36.6 Maternal care for excessive foetal growth	0.777	0.223
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.777	0.223
C18.3 Hepatic flexure	0.777	0.223
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.775	0.225
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.775	0.225
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.773	0.227
T20-T25 Burns and corrosions of external body surface, specified by site	0.772	0.228
Chapter V Mental and behavioural disorders	0.770	0.230
S60-S69 Injuries to the wrist and hand	0.770	0.230
H44.0 Purulent endophthalmitis	0.770	0.230
O21 Excessive vomiting in pregnancy	0.769	0.230
J80-J84 Other respiratory diseases principally affecting the interstitium	0.769	0.231
C77.0 Lymph nodes of head, face and neck	0.769	0.231
J92 Pleural plaque	0.769	0.231
O20.9 Haemorrhage in early pregnancy, unspecified	0.768	0.232
E50-E64 Other nutritional deficiencies	0.767	0.233
O40 Polyhydramnios	0.767	0.233
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.766	0.234
V20-V29 Motorcycle rider injured in transport accident	0.766	0.234
O00 Ectopic pregnancy	0.766	0.234
J00-J06 Acute upper respiratory infections	0.766	0.234
H43.3 Other vitreous opacities	0.765	0.235
G90-G99 Other disorders of the nervous system	0.765	0.235
C32 Malignant neoplasm of larynx	0.765	0.235
Y40.1 Cefalosporins and other -lactam antibiotics	0.764	0.236
I35.1 Aortic (valve) insufficiency	0.762	0.238
O61 Failed induction of labour	0.762	0.238
M51.2 Other specified intervertebral disk displacement	0.760	0.240
I05 Rheumatic mitral valve diseases	0.759	0.241
O16 Unspecified maternal hypertension	0.759	0.241
C18.6 Descending colon	0.759	0.241
H35.0 Background retinopathy and retinal vascular changes	0.758	0.242
O36.5 Maternal care for poor foetal growth	0.757	0.243
T80 Complications following infusion, transfusion and therapeutic injection	0.757	0.243
H43.1 Vitreous haemorrhage	0.753	0.247
I49 Other cardiac arrhythmias	0.753	0.247
H11 Other disorders of conjunctiva	0.753	0.247
H35.7 Separation of retinal layers	0.752	0.248
H44.1 Other endophthalmitis	0.751	0.248
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.750	0.250
Chapter XXII Codes for special purposes	0.750	0.250
O20.8 Other haemorrhage in early pregnancy	0.749	0.251
C19 Malignant neoplasm of rectosigmoid junction	0.749	0.251
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.749	0.251
H25 Senile cataract	0.748	0.252
I37 Pulmonary valve disorders	0.748	0.252
Q61 Cystic kidney disease	0.748	0.252
T82.4 Mechanical complication of vascular dialysis catheter	0.747	0.253
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.746	0.253
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.746	0.254
H35.9 Retinal disorder, unspecified	0.746	0.254
T81.7 Vascular complications following a procedure, not elsewhere classified	0.745	0.255
C77.9 Lymph node, unspecified	0.744	0.256
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.742	0.258
I35.9 Aortic valve disorder, unspecified	0.741	0.259
O44 Placenta praevia	0.740	0.260
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.739	0.261
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.739	0.261
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.738	0.262
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.738	0.262
T82.1 Mechanical complication of cardiac electronic device	0.738	0.262
O63.0 Prolonged first stage (of labour)	0.738	0.262
C50.3 Lower-inner quadrant of breast	0.738	0.262
O68 Labour and delivery complicated by foetal stress [distress]	0.738	0.262
T81.1 Shock during or resulting from a procedure, not elsewhere classified	0.738	0.262
Z93.1 Gastrostomy status	0.738	0.262
O02 Other abnormal products of conception	0.736	0.264
Q38-Q45 Other congenital malformations of the digestive system	0.735	0.265
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.731	0.269
S40-S49 Injuries to the shoulder and upper arm	0.731	0.269
C79 Secondary malignant neoplasm of other sites	0.730	0.270
C67.6 Ureteric orifice	0.730	0.270
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.725	0.275
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.725	0.275
I46.0 Cardiac arrest with successful resuscitation	0.725	0.275
J20-J22 Other acute lower respiratory infections	0.725	0.275
Q20-Q28 Congenital malformations of the circulatory system	0.725	0.275
T81.9 Unspecified complication of procedure	0.725	0.275
Y40.3 Macrolides	0.724	0.276
C77.5 Intrapelvic lymph nodes	0.724	0.276
T82.0 Mechanical complication of heart valve prosthesis	0.723	0.277
H36.0 Diabetic retinopathy	0.723	0.277
H44.2 Degenerative myopia	0.723	0.277
D00-D09 In situ neoplasms	0.721	0.278
T79 Certain early complications of trauma, not elsewhere classified	0.721	0.279
H35.4 Peripheral retinal degeneration	0.720	0.280
H26.4 After-cataract	0.719	0.281
Y53 Agents primarily affecting the gastro-intestinal system	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
C40-C41 Malignant neoplasms of bone and articular cartilage	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
O85-O92 Complications predominantly related to the puerperium	0.717	0.283
Y40.8 Other systemic antibiotics	0.717	0.283
S27.1 Traumatic haemothorax	0.717	0.283
X58-X59 Accidental exposure to other and unspecified factors	0.716	0.284
T87 Complications peculiar to reattachment and amputation	0.716	0.284
H25.1 Senile nuclear cataract	0.716	0.284
S29 Other and unspecified injuries of thorax	0.716	0.284
Y57 Other and unspecified drugs and medicaments	0.715	0.285
O41 Other disorders of amniotic fluid and membranes	0.715	0.285
S50-S59 Injuries to the elbow and forearm	0.714	0.286
C76 Malignant neoplasm of other and ill-defined sites	0.714	0.286
E65-E68 Obesity and other hyperalimentation	0.713	0.287
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.713	0.287
C17 Malignant neoplasm of small intestine	0.713	0.287
C23 Malignant neoplasm of gallbladder	0.713	0.287
O43 Placental disorders	0.713	0.287
H32 Chorioretinal disorders in diseases classified elsewhere	0.712	0.288
H31 Other disorders of choroid	0.712	0.288
H30 Chorioretinal inflammation	0.712	0.288
C77.3 Axillary and upper limb lymph nodes	0.712	0.288
T88 Other complications of surgical and medical care, not elsewhere classified	0.712	0.288
O24.4 Diabetes mellitus arising in pregnancy	0.711	0.289
S22.3 Fracture of rib	0.711	0.289
O69.2 Labour and delivery complicated by other cord entanglement	0.711	0.289
H26.8 Other specified cataract	0.711	0.289
O62 Abnormalities of forces of labour	0.711	0.289
Q80-Q89 Other congenital malformations	0.711	0.289
I42.9 Cardiomyopathy, unspecified	0.711	0.289
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.710	0.289
O75 Other complications of labour and delivery, not elsewhere classified	0.709	0.290
I35.0 Aortic (valve) stenosis	0.709	0.291
C67.5 Bladder neck	0.708	0.291
E16 Other disorders of pancreatic internal secretion	0.707	0.293
E46 Unspecified protein-energy malnutrition	0.707	0.293
C50.8 Overlapping lesion of breast	0.707	0.293
C66 Malignant neoplasm of ureter	0.706	0.293
C25.0 Head of pancreas	0.706	0.294
O35 Maternal care for known or suspected foetal abnormality and damage	0.706	0.294
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.706	0.294
S26 Injury of heart	0.706	0.294
S25 Injury of blood vessels of thorax	0.706	0.294
S24 Injury of nerves and spinal cord at thorax level	0.706	0.294
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.706	0.294
S21 Open wound of thorax	0.706	0.294
H35.2 Other proliferative retinopathy	0.706	0.294
H35.1 Retinopathy of prematurity	0.706	0.294
I74 Arterial embolism and thrombosis	0.705	0.295
C78.4 Secondary malignant neoplasm of small intestine	0.705	0.295
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.705	0.295
C78.1 Secondary malignant neoplasm of mediastinum	0.705	0.295
C18.8 Overlapping lesion of colon	0.705	0.295
C18.1 Appendix	0.705	0.295
H33.3 Retinal breaks without detachment	0.704	0.296
Z80 Family history of malignant neoplasm	0.703	0.297
O29 Complications of anaesthesia during pregnancy	0.702	0.298
O28 Abnormal findings on antenatal screening of mother	0.702	0.298
O22 Venous complications in pregnancy	0.702	0.298
O25 Malnutrition in pregnancy	0.702	0.298
C51-C58 Malignant neoplasms of female genital organs	0.702	0.298
E87.1 Hypo-osmolality and hyponatraemia	0.702	0.298
S19 Other and unspecified injuries of neck	0.701	0.299
O74 Complications of anaesthesia during labour and delivery	0.701	0.299
O73 Retained placenta and membranes, without haemorrhage	0.701	0.299
O71 Other obstetric trauma	0.701	0.299
O65 Obstructed labour due to maternal pelvic abnormality	0.701	0.299
O60 Preterm delivery	0.701	0.299
I35.2 Aortic (valve) stenosis with insufficiency	0.701	0.299
G70-G73 Diseases of myoneural junction and muscle	0.701	0.299
T92 Sequelae of injuries of upper limb	0.700	0.300
O80-O84 Delivery	0.700	0.300
O46 Antepartum haemorrhage, not elsewhere classified	0.699	0.301
C97 Malignant neoplasms of independent (primary) multiple sites	0.699	0.301
E83 Disorders of mineral metabolism	0.698	0.302
T90 Sequelae of injuries of head	0.697	0.303
G20-G26 Extrapyramidal and movement disorders	0.697	0.303
J14 Pneumonia due to Haemophilus influenzae	0.697	0.303
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.696	0.304
I00-I02 Acute rheumatic fever	0.696	0.304
L80-L99 Other disorders of the skin and subcutaneous tissue	0.696	0.304
I30 Acute pericarditis	0.695	0.305
T91 Sequelae of injuries of neck and trunk	0.695	0.305
H43.9 Disorder of vitreous body, unspecified	0.695	0.305
H43.2 Crystalline deposits in vitreous body	0.695	0.305
H43.0 Vitreous prolapse	0.695	0.305
S27.0 Traumatic pneumothorax	0.694	0.305
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.694	0.306
C38 Malignant neoplasm of heart, mediastinum and pleura	0.694	0.306
C31 Malignant neoplasm of accessory sinuses	0.694	0.306
C30 Malignant neoplasm of nasal cavity and middle ear	0.694	0.306
C37 Malignant neoplasm of thymus	0.694	0.306
C33 Malignant neoplasm of trachea	0.694	0.306
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.694	0.306
O64 Obstructed labour due to malposition and malpresentation of foetus	0.693	0.307
W00-W19 Falls	0.692	0.308
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.692	0.308
Y60-Y69 Misadventures to patients during surgical and medical care	0.691	0.309
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.691	0.309
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.691	0.309
I52 Other heart disorders in diseases classified elsewhere	0.690	0.309
I48 Atrial fibrillation and flutter	0.690	0.309
I43 Cardiomyopathy in diseases classified elsewhere	0.690	0.309
I41 Myocarditis in diseases classified elsewhere	0.690	0.309
I40 Acute myocarditis	0.690	0.309
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.690	0.309
I36 Nonrheumatic tricuspid valve disorders	0.690	0.309
I32 Pericarditis in diseases classified elsewhere	0.690	0.309
O47.1 False labour at or after 37 completed weeks of gestation	0.690	0.310
I42.0 Dilated cardiomyopathy	0.690	0.310
M05-M14 Inflammatory polyarthropathies	0.690	0.310
E84 Cystic fibrosis	0.688	0.312
E79 Disorders of purine and pyrimidine metabolism	0.688	0.312
E77 Disorders of glycoprotein metabolism	0.688	0.312
E76 Disorders of glycosaminoglycan metabolism	0.688	0.312
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.688	0.312
E74 Other disorders of carbohydrate metabolism	0.688	0.312
E73 Lactose intolerance	0.688	0.312
E72 Other disorders of amino-acid metabolism	0.688	0.312
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.688	0.312
E70 Disorders of aromatic amino-acid metabolism	0.688	0.312
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.688	0.312
I07 Rheumatic tricuspid valve diseases	0.688	0.312
Q50-Q56 Congenital malformations of genital organs	0.687	0.312
E85.9 Amyloidosis, unspecified	0.687	0.313
T83.1 Mechanical complication of other urinary devices and implants	0.687	0.313
S22.2 Fracture of sternum	0.687	0.313
T86.0 Bone-marrow transplant rejection	0.687	0.313
Z96.2 Presence of otological and audiological implants	0.687	0.313
Y35-Y36 Legal intervention and operations of war	0.686	0.314
Y10-Y34 Event of undetermined intent	0.686	0.314
Y00-Y09 Assault	0.686	0.314
X85-X99 Assault	0.686	0.314
X50-X57 Overexertion, travel and privation	0.686	0.314
X30-X39 Exposure to forces of nature	0.686	0.314
X20-X29 Contact with venomous animals and plants	0.686	0.314
X10-X19 Contact with heat and hot substances	0.686	0.314
X00-X09 Exposure to smoke, fire and flames	0.686	0.314
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.686	0.314
W75-W84 Other accidental threats to breathing	0.686	0.314
W65-W74 Accidental drowning and submersion	0.686	0.314
W50-W64 Exposure to animate mechanical forces	0.686	0.314
V98-V99 Other and unspecified transport accidents	0.686	0.314
V95-V97 Air and space transport accidents	0.686	0.314
V90-V94 Water transport accidents	0.686	0.314
V80-V89 Other land transport accidents	0.686	0.314
V70-V79 Bus occupant injured in transport accident	0.686	0.314
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.686	0.314
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.686	0.314
V40-V49 Car occupant injured in transport accident	0.686	0.314
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.686	0.314
V01-V09 Pedestrian injured in transport accident	0.686	0.314
O45 Premature separation of placenta [abruptio placentae]	0.686	0.314
O33 Maternal care for known or suspected disproportion	0.686	0.314
O31 Complications specific to multiple gestation	0.686	0.314
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.686	0.314
H18 Other disorders of cornea	0.685	0.315
O70.2 Third degree perineal laceration during delivery	0.683	0.317
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.683	0.317
C67.9 Bladder, unspecified	0.682	0.318
O32 Maternal care for known or suspected malpresentation of foetus	0.681	0.319
F40-F48 Neurotic, stress-related and somatoform disorders	0.681	0.319
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.680	0.320
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.680	0.320
T83.2 Mechanical complication of graft of urinary organ	0.680	0.320
Q00-Q07 Congenital malformations of the nervous system	0.679	0.321
S22.1 Multiple fractures of thoracic spine	0.679	0.321
I71 Aortic aneurysm and dissection	0.679	0.321
V10-V19 Pedal cyclist injured in transport accident	0.679	0.321
S99 Other and unspecified injuries of ankle and foot	0.678	0.322
L20-L30 Dermatitis and eczema	0.677	0.323
S10 Superficial injury of neck	0.677	0.323
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.677	0.323
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.677	0.323
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.676	0.323
Q35-Q37 Cleft lip and cleft palate	0.676	0.323
Q30-Q34 Congenital malformations of the respiratory system	0.676	0.323
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.676	0.323
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.676	0.324
Q61.3 Polycystic kidney, unspecified	0.676	0.324
J81 Pulmonary oedema	0.675	0.325
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.675	0.325
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.675	0.325
T82.3 Mechanical complication of other vascular grafts	0.675	0.325
S22.0 Fracture of thoracic vertebra	0.674	0.325
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.673	0.327
I08.0 Disorders of both mitral and aortic valves	0.673	0.327
F30-F39 Mood [affective] disorders	0.673	0.327
C34.8 Overlapping lesion of bronchus and lung	0.672	0.328
T81.6 Acute reaction to foreign substance accidentally left during a procedure	0.672	0.328
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.672	0.328
H20.9 Iridocyclitis, unspecified	0.671	0.328
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.671	0.329
I08.1 Disorders of both mitral and tricuspid valves	0.671	0.329
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.671	0.329
S14 Injury of nerves and spinal cord at neck level	0.671	0.329
E88 Other metabolic disorders	0.671	0.329
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.671	0.329
T36-T50 Poisoning by drugs, medicaments and biological substances	0.671	0.329
O08 Complications following abortion and ectopic and molar pregnancy	0.670	0.330
O07 Failed attempted abortion	0.670	0.330
O06 Unspecified abortion	0.670	0.330
O05 Other abortion	0.670	0.330
O01 Hydatidiform mole	0.670	0.330
H27 Other disorders of lens	0.670	0.330
I42.8 Other cardiomyopathies	0.670	0.330
C50.0 Nipple and areola	0.670	0.330
S62 Fracture at wrist and hand level	0.669	0.331
S20.2 Contusion of thorax	0.669	0.331
M65-M68 Disorders of synovium and tendon	0.668	0.331
C34.9 Bronchus or lung, unspecified	0.668	0.332
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.667	0.333
E87.4 Mixed disorder of acid-base balance	0.667	0.333
E87.3 Alkalosis	0.667	0.333
E22 Hyperfunction of pituitary gland	0.667	0.333
C18.7 Sigmoid colon	0.667	0.333
C21.1 Anal canal	0.667	0.333
C25.1 Body of pancreas	0.667	0.333
E10.1 With ketoacidosis	0.666	0.334
G96 Other disorders of central nervous system	0.666	0.334
I38 Endocarditis, valve unspecified	0.666	0.334
C34.0 Main bronchus	0.665	0.335
T93 Sequelae of injuries of lower limb	0.665	0.335
S60 Superficial injury of wrist and hand	0.665	0.335
C68 Malignant neoplasm of other and unspecified urinary organs	0.664	0.336
C65 Malignant neoplasm of renal pelvis	0.664	0.336
C26.0 Intestinal tract, part unspecified	0.664	0.336
O66 Other obstructed labour	0.663	0.337
E87.0 Hyperosmolality and hypernatraemia	0.663	0.337
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.663	0.337
H49 Paralytic strabismus	0.662	0.338
O34 Maternal care for known or suspected abnormality of pelvic organs	0.662	0.338
X40-X49 Accidental poisoning by and exposure to noxious substances	0.661	0.338
J92.9 Pleural plaque without asbestos	0.661	0.339
O72.1 Other immediate postpartum haemorrhage	0.661	0.339
L91 Hypertrophic disorders of skin	0.661	0.339
J98 Other respiratory disorders	0.661	0.339
I49.8 Other specified cardiac arrhythmias	0.661	0.339
E85.4 Organ-limited amyloidosis	0.661	0.339
Z98 Other postsurgical states	0.661	0.339
O36.9 Maternal care for foetal problem, unspecified	0.660	0.340
I09 Other rheumatic heart diseases	0.660	0.340
I06 Rheumatic aortic valve diseases	0.660	0.340
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.660	0.340
S22.9 Fracture of bony thorax, part unspecified	0.658	0.342
S22.8 Fracture of other parts of bony thorax	0.658	0.342
S22.5 Flail chest	0.658	0.342
H55-H59 Other disorders of eye and adnexa	0.658	0.342
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.657	0.343
C21.0 Anus, unspecified	0.657	0.343
H47 Other disorders of optic [2nd] nerve and visual pathways	0.656	0.344
T86.8 Failure and rejection of other transplanted organs and tissues	0.656	0.344
O72.0 Third-stage haemorrhage	0.656	0.344
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.656	0.344
Chapter VIII Diseases of the ear and mastoid process	0.654	0.346
Z96.8 Presence of other specified functional implants	0.654	0.346
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.653	0.347
O36.4 Maternal care for intra-uterine death	0.653	0.347
O36.3 Maternal care for signs of foetal hypoxia	0.653	0.347
O36.2 Maternal care for hydrops foetalis	0.653	0.347
O36.1 Maternal care for other isoimmunisation	0.653	0.347
Y52 Agents primarily affecting the cardiovascular system	0.653	0.347

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations